Plasma collection system and method

Abstract

The invention discloses a plasma collection system and method. The plasma collection system comprises a blood collection pump, a centrifugal module, a plasma scale clamp, an air detector, a red blood cell detector, an anticoagulant scale, an anticoagulant pump, a filter, a control module and a pressure sensor. According to the scheme, blood can be automatically collected and centrifuged, plasma is separated, red blood cells are returned and transfused, a traditional manual collection mode is replaced, the burden of medical staff is reduced, the blood collection efficiency is improved, the whole blood collection process is completed in a closed circulation environment, and possible cross infection is avoided; meanwhile, the pipeline pressure in the blood sampling process is monitored in real time, and the blood sampling speed is changed according to the change of the pipeline pressure, so that the blood sampling process can adaptively change along with the change of the physiological state of the user, and the discomfort of the user in the blood sampling process is reduced.

Description

Technical Field

[0001] The present invention relates to the technical field of blood collection equipment, and in particular to a plasma collection system and method. Background Art

[0002] The existing automatic blood collection system collects whole blood from the donor's arm vein, and after processing through a centrifugal separation system, plasma is extracted from the whole blood. After multiple cycles of blood collection and processing, a certain amount of plasma is finally extracted. The existing blood collection and processing process does not protect and monitor the status of the blood donor, and the blood drawing speed cannot be adjusted in real time according to the status of the blood donor. Summary of the invention

[0003] In view of this, the present invention provides a plasma collection system and method, which can automatically collect and centrifuge blood, separate plasma, and return red blood cells, replacing the traditional manual collection method, reducing the burden on medical personnel, speeding up the blood collection efficiency, and completing the entire blood collection process in a closed circulation environment to avoid possible cross infection; at the same time, the pipeline pressure during the blood collection process is monitored in real time, and the blood collection speed is changed according to the change in the pipeline pressure, so that the blood collection process can adapt to the changes in the user's physiological state, reducing the user's discomfort during the blood collection process.

[0004] To achieve the above object, the present invention provides the following technical solutions:

[0005] A plasma collection system, comprising:

[0006] A blood sampling pump, used to transport the blood in the user's body to the centrifugal module through a pipeline;

[0007] A centrifugal module, used for separating plasma after centrifuging blood;

[0008] A plasma weighing clamp, used for fixing the plasma container and obtaining the weight of the plasma container;

[0009] an air detector covering a portion of the pipeline between the user and the centrifugal module and used to monitor air bubbles in the pipeline;

[0010] a red blood cell detector, covering a portion of the pipeline between the centrifugal module and the plasma container, and used for monitoring the red blood cell concentration in the blood;

[0011] Anticoagulant scale, used to provide a fixed position for the anticoagulant container and obtain the weight in real time;

[0012] an anticoagulant pump, used for delivering the anticoagulant into the centrifugal module;

[0013] A filter support, used for supporting and replacing a filter of a portion of the pipeline between the blood sampling pump and the centrifugal module;

[0014] A control module, which is in communication with the anticoagulant pump and the blood sampling pump and is used to change the operating speed of the anticoagulant pump and the blood sampling pump;

[0015] The pressure sensor is connected to the control module for real-time acquisition of pipeline pressure. The control module changes the operating speed of the anticoagulant pump and the blood sampling pump according to the pipeline pressure.

[0016] Preferably, it also includes an identity authentication module, which is communicatively connected to the control module and is used to at least obtain the user's identity information and / or biometric information.

[0017] Preferably, a barcode scanning module is further included, which is communicatively connected to the control module and is used to obtain the barcode information of the plasma container and then match the identity information with the barcode information.

[0018] Preferably, the control module is used to change the operating speed of the blood sampling pump according to the identity information and / or biological information of the user.

[0019] Preferably, it also includes a physiological saline scale for providing a fixed position for the physiological saline container and obtaining the weight in real time. The blood sampling pump has a reverse working state. When the blood sampling pump reverses, the physiological saline flushes the centrifugal module through the pipeline and is delivered to the user.

[0020] Preferably, the anticoagulant scale has a first starting weight that is the same as the initial weight of a unit of anticoagulant, and the anticoagulant scale allows the control module to start the blood sampling pump after the consumables having the first starting weight are fixed thereon.

[0021] Preferably, the physiological saline scale has a second starting weight that is the same as the initial weight of a unit of physiological saline. After the physiological saline scale passes through the consumables fixed with the second starting weight, the control module is allowed to start the blood collection pump, and the first starting weight is different from the second starting weight.

[0022] In another aspect, the present invention provides a method for collecting plasma, comprising the following steps:

[0023] S100, confirming the user's identity and biometric information, and matching and selecting a blood donation mode from a preset database;

[0024] S200, detecting and monitoring the user's physiological indicators in real time, and matching blood donation suggestions from a preset database according to the user's current physical condition;

[0025] S300, after blood drawing starts, the blood sampling pump rotates to deliver the blood in the pipeline to the centrifugal module, and the anticoagulant pump delivers the anticoagulant to the centrifugal module, and after centrifugation, the anticoagulant is delivered to the plasma container; the number of revolutions of the blood sampling pump and the anticoagulant pump, as well as the weight change of the remaining anticoagulant are monitored in real time, and the whole blood volume and anticoagulant dosage in the centrifugal module are calculated; the weight of the plasma container is obtained in real time, and when the calculated result differs from the obtained weight of the plasma container by more than a threshold value, blood drawing is stopped;

[0026] S400, after blood drawing begins, real-time monitoring of the pressure in the pipeline;

[0027] When the pipeline pressure exceeds the threshold, the rotation speed of the blood sampling pump is continuously reduced until the pressure returns to normal;

[0028] When the pipeline pressure is less than a threshold value, the rotation speed of the blood sampling pump is continuously increased until the pressure returns to normal;

[0029] When the pipeline pressure is within the expected range, the blood sampling pump operates at the maximum speed;

[0030] After blood drawing starts, if the user's physiological indicators are abnormal, the rotation speeds of the blood drawing pump and the anticoagulant pump are adjusted; when the user's physiological indicators still do not meet expectations, blood drawing is stopped or blood transfusion is started;

[0031] After the blood drawing starts, the pipeline at the outlet of the centrifugal module is monitored in real time, and when overflow of red blood cells is detected, the blood drawing is stopped;

[0032] S500: After a predetermined weight of plasma is detected in the plasma container, blood transfusion is stopped, the centrifugal module is flushed with physiological saline, and the blood collection pump reverses and retransfuses the remaining blood in the pipeline and the centrifugal module.

[0033] Preferably, in step S400: after the blood drawing starts, real-time monitoring of the pressure of the pipeline includes: expressing the pipeline pressure in terms of the height of a mercury column, and setting the initial speed of the blood drawing pump to V (rpm):

[0034] When the line pressure is less than -80 mmHg, stop drawing blood;

[0035] When -79mmHg<the pipeline pressure<-51mmHg, the blood sampling pump is controlled to increase the operating speed, and the speed of the blood sampling pump increases by V / (-51-(-79)) each time the pipeline pressure increases by 1mmHg;

[0036] When -50 mmHg<the pipeline pressure<50 mmHg, the blood sampling pump operates at the initial speed V;

[0037] When 51 mmHg<the pipeline pressure<79 mmHg, the blood sampling pump is controlled to reduce the rotation speed, and the speed of the blood sampling pump is reduced by V / (79-51) each time the pipeline pressure increases by 1 mmHg;

[0038] When the line pressure is ≤80 mmHg, blood drawing is stopped.

[0039] Preferably, in step S500: when the blood sampling pump is reversed and infused, real-time monitoring of the pressure of the pipeline includes: expressing the pipeline pressure in terms of the height of a mercury column, and setting the initial speed of the blood sampling pump to v (rpm):

[0040] When the line pressure is ≥260 mmHg, stop the reinfusion;

[0041] When 101 mmHg<the pipeline pressure<259 mmHg, the blood sampling pump is controlled to reduce the operating speed, and the speed of the blood sampling pump is reduced by V / (259-101) each time the pipeline pressure increases by 1 mmHg;

[0042] When 0 mmHg<line pressure<100 mmHg, the blood sampling pump operates at the maximum speed;

[0043] When the line pressure is less than 0 mmHg, stop the reinfusion.

[0044] It can be seen from the above technical solutions that the plasma collection system provided by the present invention can automatically collect and centrifuge blood, separate plasma, and return red blood cells for transfusion, replacing the traditional manual collection method, reducing the burden on medical personnel, speeding up the efficiency of blood collection, and completing the entire blood collection process in a closed circulation environment to avoid possible cross infection; at the same time, the pipeline pressure during the blood collection process is monitored in real time, and the blood collection speed is changed according to the change in the pipeline pressure, so that the blood collection process can adapt to the changes in the user's physiological state, reducing the user's discomfort during the blood collection process. BRIEF DESCRIPTION OF THE DRAWINGS

[0045] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0046] Figure 1 is a flow chart showing a plasma collection method according to an exemplary embodiment;

[0047] Figure 2 is a schematic diagram showing a plasma collection system according to an exemplary embodiment;

[0048] Figure 3 is a schematic diagram showing the structure of a blood sampling pump according to an exemplary embodiment;

[0049] Figure 4 is a schematic diagram showing a pipe clamp structure according to an exemplary embodiment;

[0050] Figure 5 According to an exemplary embodiment Figure 4 The middle is an enlarged view of part A showing the structure of the pipe sleeve;

[0051] Figure 6 is a schematic diagram showing a plasma weighing clamp structure according to an exemplary embodiment;

[0052] Figure 7 is a view showing the structure of a plasma scale according to an exemplary embodiment;

[0053] Figure 8 According to an exemplary embodiment Figure 7 The middle is an enlarged view of part B showing the structure of the auxiliary arm;

[0054] Fig. 9 is a schematic diagram showing the structure of an anticoagulant according to an exemplary embodiment;

[0055] Fig.10 is a schematic diagram showing the structure of an anticoagulant body according to an exemplary embodiment;

[0056] Fig.11 is a schematic diagram showing a damping metal ring structure according to an exemplary embodiment;

[0057] Fig.12 According to an exemplary embodiment Fig. 9 The middle is an enlarged view of the C part showing the protection plug structure;

[0058] Fig.13 According to an exemplary embodiment Fig.10 The middle is an enlarged view of the D portion showing the structure of the protective cap.

[0059] Reference numerals:

[0060] 1. Machine body; 11. Identity verification module; 12. Barcode scanning module; 13. Control module; 14. Air detector; 15. Filter bracket; 16. Pressure sensor; 2. Blood sampling pump; 3. Anticoagulant pump; 4. Red blood cell detector; 5. Anticoagulant scale; 51. Mounting table; 52. Damping support rod; 53. Physiological saline scale; 54. Anticoagulant scale body; 541. Connecting block; 542. Hook; 543. Pressing plate; 544. Damping metal ring; 545. Bottom plate; 546. Downward pressure trigger alarm; 547. Protective bolt; 548. Protective cap; 55. Extrusion unit; 55 1. Disassembly and assembly pipe mouth; 552. Transition part; 56. Pump body shell; 561. Insertion port; 57. Lifting unit; 58. Pipe clamp; 581. Pipe sleeve; 582. Pipeline; 583. Reduced diameter blocking part; 59. Scale body shell; 6. Centrifugal module; 7. Plasma scale clamp; 71. Plasma scale body; 72. Support body; 721. Second arc surface; 722. Tie end; 73. Secondary support arm; 731. First arc surface; 732. Third arc surface; 733. Torsion spring installation groove; 74. Main support arm; 741. Clamping part; 75. Limiting hanging end; 751. Limiting part; 76. Tension spring. DETAILED DESCRIPTION

[0061] The present invention discloses a plasma collection system and method, which can automatically collect and centrifuge blood, separate plasma, and return red blood cells for transfusion, replacing the traditional manual collection method, reducing the burden on medical personnel, accelerating the blood collection efficiency, and completing the entire blood collection process in a closed circulation environment to avoid possible cross infection; at the same time, the pipeline pressure during the blood collection process is monitored in real time, and the blood collection speed is changed according to the change of the pipeline pressure, so that the blood collection process can adapt to the changes in the user's physiological state, reducing the user's discomfort during the blood collection process.

[0062] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0063] In an exemplary embodiment of the present disclosure, a plasma collection system and method are provided, such as Figure 1 As shown, Figure 1 is a flow chart showing a plasma collection method according to an exemplary embodiment; Figure 2 is a schematic diagram showing a plasma collection system according to an exemplary embodiment; Figure 3 is a schematic diagram showing the structure of a blood sampling pump according to an exemplary embodiment; Figure 4is a schematic diagram showing a pipe clamp structure according to an exemplary embodiment; Figure 5 According to an exemplary embodiment Figure 4 The middle is an enlarged view of part A showing the structure of the pipe sleeve; Figure 6 is a schematic diagram showing a plasma weighing clamp structure according to an exemplary embodiment; Figure 7 is a view showing the structure of a plasma scale according to an exemplary embodiment; Figure 8 According to an exemplary embodiment Figure 7 The middle is an enlarged view of part B showing the structure of the auxiliary arm; Fig. 9 is a schematic diagram showing the structure of an anticoagulant according to an exemplary embodiment; Fig.10 is a schematic diagram showing the structure of an anticoagulant body according to an exemplary embodiment; Fig.11 is a schematic diagram showing a damping metal ring structure according to an exemplary embodiment; Fig.12 According to an exemplary embodiment Fig. 9 The middle is an enlarged view of the C part showing the protection plug structure; Fig.13 According to an exemplary embodiment Fig.10 The middle is an enlarged view of the D part of the protective cap structure. Figures 1 to 13 Provide explanation.

[0064] Some specific implementation modes described below are intended to facilitate those skilled in the art to understand the present embodiment, and the present embodiment is not limited to some specific implementation modes described below.

[0065] Reference Figure 1 and Figure 2 An exemplary embodiment of the present disclosure provides a plasma collection system, the plasma collection system comprising:

[0066] The blood sampling pump 2 is used to transport the blood in the user's body to the centrifugal module 6 through the pipeline 582;

[0067] A centrifugal module 6, used for separating plasma after centrifuging blood;

[0068] A plasma weighing clamp 7, used for fixing the plasma container and obtaining the weight of the plasma container;

[0069] an air detector 14 covering a portion of the pipeline 582 between the user and the centrifugal module 6 and used to monitor air bubbles in the pipeline 582;

[0070] The red blood cell detector 4 covers a portion of the pipeline 582 between the centrifugal module 6 and the plasma container and is used to monitor the red blood cell concentration in the blood;

[0071] An anticoagulant scale 5, used to provide a fixed position for an anticoagulant container and obtain the weight in real time;

[0072] an anticoagulant pump 3, used for delivering the anticoagulant into the centrifugal module 6;

[0073] The filter support 15 is used to support and replace the filter of the part of the pipeline 582 between the blood sampling pump 2 and the centrifugal module 6, and the filter is used to filter the bubbles in the blood in the pipeline 582;

[0074] The control module 13 is in communication with the anticoagulant pump 3 and the blood sampling pump 2 and is used to change the operating speed of the anticoagulant pump 3 and the blood sampling pump 2;

[0075] The pressure sensor 16 is connected to the control module 13 for real-time acquisition of the pipeline pressure. The control module 13 changes the operating speeds of the anticoagulant pump 3 and the blood sampling pump 2 according to the pipeline pressure.

[0076] For example, refer to Figure 1 and Figure 2 The plasma collection system includes a body 1, which is in a cubic shape and is used to be placed at a predetermined blood collection position. A blood collection pump 2 is fixedly connected to the top surface of the body 1 and is located on one side of the body 1, and is used to provide power for the blood in the pipeline 582 to flow along the pipeline 582. Part of the physical structure of the blood collection pump 2 is hidden inside the body 1, and the pipeline 582 connection part of the blood collection pump 2 is exposed above the top surface of the body 1. The blood collection pump 2 is connected to the control module 13 by communication, such as wireless signal connection or cable communication, and the operation of the blood collection pump 2 is regulated by the control module 13.

[0077] Reference Figure 3 and Figure 4 The blood sampling pump 2 is the automatic tube removal device disclosed in the present application, which includes a lifting unit 57 fixedly connected to the inside of the body 1, a tube clamp 58 fixed to the top of the lifting unit 57, a tube sleeve 581 that can be inserted into the tube clamp 58 and laterally clamped with the tube clamp 58, a pump body shell 56 fixed to the top surface of the body 1, and an extrusion unit 55 rotatably connected to the inside of the pump body shell 56. The lifting unit 57 includes an electric push rod fixedly connected to the inner wall of the body 1 in a vertical posture, and the piston rod end of the electric push rod extends upward and can extend from the top surface of the body 1 and above the body 1.

[0078] Reference Figure 3 and Figure 5The pump housing 56 is provided with two insertion openings 561 for the pipeline 582 to pass through. The two insertion openings 561 are located on the same side of the pump housing 56. For example, the two insertion openings 561 are both provided on the side of the pump housing 56 facing the electric push rod. The two insertion openings 561 are spaced apart. The interior of the pump housing 56 is hollow. The two insertion openings 561 penetrate the pump housing 56 in the horizontal direction, so that the pipeline 582 can be inserted from one insertion opening 561 and then extended from the other insertion opening 561. The rotation axis of the extrusion unit 55 is vertically arranged, and the physical structure of the driving part of the extrusion unit 55 is hidden inside the machine body 1. For example, the extrusion unit 55 is realized by a motor to realize fixed-axis rotation inside the pump housing 56. The aforementioned motor is fixedly connected to the inside of the machine body 1 with the output shaft vertically upward. The top edge of the extrusion unit 55 protrudes outward and is close to the pump body shell 56. A space is formed below the top edge of the extrusion unit 55 for the pipeline 582 to extend into. After the pipeline 582 is extended into, it is compressed section by section under the extrusion action of the extrusion unit 55, thereby driving the medium inside the pipeline 582 to flow along the pipeline 582, that is, the extrusion unit 55 is consistent with the peristaltic pump principle. The top edge of the extrusion unit 55 is provided with a disassembly pipe opening 551 for the pipeline 582 to extend vertically into the pump body shell 56. There are two disassembly pipe openings 551 and they are spaced apart. The two disassembly pipe openings 551 can correspond to the two insertion pipe openings 561 respectively after the extrusion unit 55 is rotated to a predetermined position. The disassembly nozzle 551 penetrates part of the top edge of the extrusion unit 55 in the vertical direction and communicates with the interior of the pump housing 56. The gap between the other part of the top edge of the extrusion unit 55 and the outer wall of the pump housing 56 is matched. The gap between the other part of the top edge of the extrusion unit 55 and the outer wall of the pump housing 56 is smaller than the outer diameter of the pipeline 582. For example, if the outer diameter of the pipeline 582 is 1 cm, the gap between the other part of the top edge of the extrusion unit 55 and the outer wall of the pump housing 56 can be 5 mm. The top edge of the extrusion unit 55 on one side of the disassembly nozzle 551 has a transition portion 552 in the shape of an inclined plane. The inclined surface of the transition portion 552 is arranged away from the pump housing 56 in the direction of the disassembly nozzle 551. The transition portion 552 extends from the bottom edge of the disassembly nozzle 551 to the top edge of the disassembly nozzle 551.

[0079] Reference Figure 4 and Figure 6There are two pipe clamps 58, one of which is fixedly connected to the top of the piston rod of the electric push rod as the lifting unit 57, for example, it is threadedly connected to the top of the piston rod of the electric push rod. This pipe clamp 58 is always located above the top surface of the body 1, that is, when the piston rod of the electric push rod is retracted to the maximum extent, the aforementioned pipe clamp 58 is also exposed from the top surface of the body 1. The other pipe clamp 58 is fixedly connected to the top surface of the body 1 on the side of the aforementioned pipe clamp 58 fixed to the electric push rod. In order to achieve the sealing of the body 1, a rubber ring or a sealing rubber sleeve can also be fixed on the body 1 at the bottom end of the pipe clamp 58, which is used to achieve the sealing of the body 1 at this point by squeezing the aforementioned sealing rubber sleeve when the electric push rod is retracted to the maximum extent. The pipe clamp 58 is a C-shaped structure, that is, an opening is opened on the outer wall of the pipe clamp 58 for the pipeline 582 to be inserted into the pipe clamp 58 after being squeezed, that is, the end of the opening on the pipe clamp 58 facing the pump housing 56 has a reduced diameter blocking portion 583. The pipe sleeve 581 is used to be fixedly connected to the pipe 582. For example, when the pipe 582 used is purchased from outside, the pipe sleeve 581 can be sleeved on a predetermined position on the pipe 582 and then fixedly connected to the pipe sleeve 582 by bonding. After the pipe 582 is installed inside the pipe clamp 58, part of the pipe sleeve 581 is also built into the pipe clamp 58, and the end of the pipe sleeve 581 facing the pump housing 56 abuts against the reduced diameter blocking portion 583, and the reduced diameter blocking portion 583 prevents the pipe sleeve 581 from moving toward the pump housing 56. When the pipe 582 moves toward the pump housing 56, that is, when the extrusion unit 55 squeezes the pipe 582 between the pump housing 56 and the extrusion unit 55, the pipe sleeve 581 can overcome the tendency of the pipe 582 to move toward the inside of the pump housing 56 after being rubbed, so that the pipe 582 can maintain the stability of the current position and posture; when the pipe 582 used is used in conjunction with the aforementioned pipe clamp 58, the pipe sleeve 581 is already fixed on the pipe 582, and there is no need to fix the pipe sleeve 581 at a predetermined position on the pipe 582. It should be understood that the two pipe clamps 58 can also be fixed with the lifting units 57 respectively, as long as the two pipe clamps 58 can generate a height difference under the drive of the two lifting units 57.

[0080] When the pipe 582 inside the pump housing 56 is disassembled, the squeezing unit 55 is controlled to rotate to the position where the disassembly pipe opening 551 corresponds to the insertion pipe opening 561. At this time, the two disassembly pipe openings 551 correspond to the positions of the two insertion pipe openings 561 respectively, and the electric push rod is controlled to raise a pipe clamp 58. At this time, the pipe 582 connected to the aforementioned raised pipe clamp 58 is stretched and lifted. The pipe 582 on the pipe clamp 58 is lifted from the inside of the insertion pipe opening 561 to the inside of the disassembly pipe opening 551. As the squeezing unit 55 rotates, the aforementioned part of the pipe 582 is correspondingly The transition part 552 on the disassembly pipe mouth 551 is used to abut and continuously apply extrusion. The aforementioned part of the pipeline 582 can be gradually squeezed out from the gap between the top edge of the extrusion unit 55 and the pump body shell 56 by the transition part 552 as the extrusion unit 55 rotates. After the extrusion unit 55 rotates one circle, the pipeline 582 originally installed between the pump body shell 56 and the top edge of the extrusion unit 55 can be completely squeezed out by the transition part 552. At this time, it is only necessary to remove the pipe sleeve 581 together with the pipeline 582 from the pipe clamp 58 to realize the quick disassembly of the pipeline 582. As for the installation of the pipeline 582, since the aforementioned extrusion unit 55, pump body shell 56, and pipe clamp 58 are all improvements made based on the peristaltic pump and blood sampling pump in the prior art, the installation of the pipeline 582 is consistent with the installation method of the peristaltic pump, blood sampling pump, etc. in the prior art, and will not be repeated here.

[0081] Continue to refer to Figure 1 The centrifugal module 6 is fixed to the top surface of the body 1 and is located at the central position of the body 1. It is used to centrifuge the whole blood gathered at the centrifugal module 6 through the pipeline 582 to separate the plasma. The centrifugal module 6 is communicated with the control module 13, such as a wireless signal connection or a cable communication. The operation of the centrifugal module 6 is regulated by the control module 13.

[0082] Reference Figure 1 and Figure 5 The plasma weighing clamp 7 is fixed to the top surface of the body 1 and extends from one side of the body 1 to the outside of the body 1, and is used to fix the plasma container, for example, it can hang or clamp the plasma container. The plasma weighing clamp 7 has a weighing function and is connected to the control module 13 for communication, such as wireless signal connection or cable communication. The control module 13 can obtain the weight of the plasma in the plasma container according to the signal sent by the plasma weighing clamp 7, and judge whether the blood collection process is normal or not. For example, the signal representing the weight of the plasma inside the plasma container sent by the plasma weighing clamp 7 to the control module 13 is different from the expected plasma weight calculated by the control module 13 through the number of rotations of the blood collection pump 2, or the difference between the two exceeds the threshold value, the control module 13 can choose to control the blood collection pump 2 to stop, or send an alarm signal to prompt the operator to check.

[0083] Reference Figure 6 and Figure 7 The plasma scale clip 7 is a multi-purpose scale bracket that is easy to disassemble and assemble disclosed in the present application, which includes a plasma scale body 71 fixed inside the body 1, a bracket main body 72 fixed to the end of the plasma scale body 71, two main arms 74 hinged to the ends of the bracket main body 72, and two secondary arms 73 hinged to the two main arms 74. The plasma scale body 71 is fixed inside the body 1 in a horizontal position and extends to the outside of the body 1, the bracket main body 72 is fixedly connected to the end of the plasma scale body 71 extending toward the outside of the body 1 in a horizontal position, the bracket main body 72 extends along the length direction of the plasma scale body 71, one end of the bracket main body 72 is fixedly connected to one end of the plasma scale body 71, and the other end of the bracket main body 72 extends from the side wall of the body 1 to the outside of the body 1. The two main arms 74 are relatively distributed on both sides of the end of the bracket body 72 extending outside the machine body 1, one end of the main arm 74 is hinged to the end of the bracket body 72, and the other end extends to the outside of the machine body 1 in a horizontal posture, and the rotation axis of the main arm 74 is vertically arranged. One end of the secondary arm 73 is hinged to the main arm 74, and the other end extends toward the space formed between the two main arms 74 and extends in the direction away from the machine body 1.

[0084] Reference Figure 6 and Figure 8The bracket body 72 is hingedly connected with a tension spring 76, one end of the tension spring 76 is hingedly connected to the bracket body 72, and the other end is hingedly connected to the main support arm 74. The tension spring 76 is in a horizontal position and the rotation axis is vertically arranged. The end of the main support arm 74 hinged to the bracket body 72 extends into the space between the two main support arms 74 and is arranged toward the body 1 to form a tie end 722. The tension spring 76 is hingedly connected to the tie end 722 of the main support arm 74 extending toward the body 1. When the tension spring 76 is in a natural state, the two main support arms 74 are arranged along the length direction of the bracket body 72. The ends of the two main arms 74 away from the body 1 are fixedly connected to the limited suspension ends 75, which are in a horizontal column structure, and the ends of the limited suspension ends 75 away from the support body 72 have a truncated cone-shaped limiting portion 751 with a horizontal axis and coaxially arranged with the limited suspension ends 75, the end of the limiting portion 751 facing the support body 72 is in an expanded diameter shape, and the end of the limiting portion 751 away from the support body 72 is in a reduced diameter shape, so that the limiting portion 751 can be more easily inserted into the mounting hole on the plasma container, and reduce the possibility of the plasma container falling from the limited suspension end 75. When the tension spring 76 is in a natural state, the limited suspension end 75 and the limiting portion 751 are both in a horizontal posture and extend along the length direction of the support body 72. For a cylindrical or box-shaped plasma container, the two main arms 74 and the limiting hanging ends 75 can be separated in a posture away from each other, so that the space between the two main arms 74 is increased, and the cylindrical plasma container can be clamped between the two main arms 74 or the two limiting hanging ends 75, and fixed by the clamping action between the two main arms 74 or the two limiting hanging ends 75, or fixed by clamping and supporting the cylinder through the two main arms 74 or the two limiting hanging ends 75. In order to further reduce the possibility of the plasma container falling off from between the two main arms 74, the ends of the two main arms 74 facing away from the body 1 are close to each other to form a clamping portion 741, which is used to reduce the opening size of the space formed between the two main arms 74. The two secondary arms 73 are provided with a torsion spring installation groove 733, which extends from the end of the secondary arm 73 hinged to the main arm 74 to the other end of the secondary arm 73. The interior of the torsion spring installation groove 733 is used to fix the torsion spring, which is sleeved on the rotating shaft of the secondary arm 73. One end of the torsion spring is fixedly connected to the main arm 74, and the other end is fixedly connected to the secondary arm 73. When the torsion spring is in a natural state, the two secondary arms 73 extend toward the space between the two main arms 74 and away from the body 1. For a cylindrical or box-shaped plasma container, after the plasma container enters the space between the two main arms 74, the two secondary arms 73 are pressed to rotate toward the body 1. At the same time, the two secondary arms 73 exert pressure on the plasma container under the action of the torsion spring, so that the plasma container can stay between the two main arms 74 more stably, increase the contact point of the plasma container between the two main arms 74, and reduce the possibility of the plasma container shaking and falling between the two main arms 74.A first arc surface 731 for adapting to a cylindrical plasma container is provided on the side wall of the secondary arm 73 facing away from the body 1, thereby increasing the contact area between the secondary arm 73 and the plasma container. For a cylindrical plasma container with a smaller volume, a second arc surface 721 is formed at the end of the support body 72 facing away from the body 1, and a third arc surface 732 is provided on the side wall of the secondary arm 73 facing the body 1. The cylindrical plasma container with a smaller volume can continue to enter the space between the two secondary arms 73 after entering the space between the two main arms 74. The two secondary arms 73 rotate outward in a mutually separated posture after being compressed. The second arc surface 721 and the third arc surface 732 respectively increase the contact area with the plasma container, so that the plasma container can be fixed more stably at the current position.

[0085] There are multiple air detectors 14, which can be fixed to the side wall of the body 1 or to the top surface of the body 1. The position of the air detector 14 can be adaptively set according to the pipeline 582 that the air detector 14 needs to detect, wherein at least one air detector 14 is located between the user and the filter bracket 15, and at least one air detector 14 is located between the filter bracket 15 and the blood sampling pump 2. The air detector 14 is connected to the control module 13 by communication, such as wireless signal connection or cable communication. The control module 13 can determine whether there are bubbles that affect the blood sampling process in the pipeline 582 of the current section according to the detection signal sent by the air detector 14, and change the expected plasma weight calculated by the number of rotations of the blood sampling pump 2 in real time according to these signals representing the bubbles. Some bubbles that do not affect the blood sampling process can be ignored. For bubbles that may affect the blood sampling process, the control module 13 can choose to control the blood sampling pump 2 to stop, or send an alarm signal to prompt the operator to check. The operator can set the judgment rules for bubbles that affect the blood sampling process, such as the size of the bubbles, or the total amount of bubbles per unit time.

[0086] The red blood cell detector 4 is fixed to the top surface of the body 1 and is located on one side of the body 1. The red blood cell detector 4 and the blood collection pump 2 are arranged on two opposite sides of the top surface of the body 1, and the red blood cell detector 4 is located between the centrifugal module 6 and the plasma weighing clamp 7. The red blood cell detector 4 can detect the plasma flowing out after centrifugation of the centrifugal module 6, and can alarm in time when red blood cell overflow is detected. The red blood cell detector 4 is connected to the control module 13 for communication, such as wireless signal connection, or through cable communication. The control module 13 can control the blood collection pump 2 to stop in time after obtaining the red blood cell overflow signal sent by the red blood cell detector 4, thereby reducing the possibility of overflowed red blood cells contaminating plasma.

[0087] Reference Fig. 9 and Fig.10The anticoagulant scale 5 is fixed on the body 1 and extends from the top surface of the body 1 to the top of the body 1. The anticoagulant scale 5 has a weighing function and is connected to the control module 13 for communication, such as wireless signal communication or cable communication. The signal emitted by the anticoagulant scale 5 can represent the weight of the remaining anticoagulant, that is, it can represent the weight of the anticoagulant injected into the pipeline 582. Since the anticoagulant enters the centrifugal module 6 together with the whole blood and flows into the plasma container with the plasma after centrifugation, the control module 13 can obtain a more accurate judgment on the weight of the plasma inside the plasma container, thereby reducing the possibility of false alarms or timeout alarms.

[0088] Reference Fig. 9 and Fig.10 The anticoagulant scale 5 is a rotary scale with adjustable height in silence disclosed in the present application, comprising a damping support rod 52 fixedly connected to the body 1, a scale housing 59 rotatably connected to the top of the damping support rod 52, an anticoagulant scale 54 fixed inside the scale housing 59, a hook 542 fixed to the anticoagulant scale 54 and extending outside the scale housing 59, and a protective device fixed inside the scale housing 59 for limiting the maximum deformation position of the anticoagulant scale 54. The anticoagulant scale 54 is the same as the scale used in the blood sampling device in the prior art, so it will not be described in detail. In order to connect the hook 542 to the anticoagulation scale 54 so that the anticoagulation scale 54 can achieve the effects of weighing and the hook 542, the hook-shaped bottom end of the hook 542 extends from the bottom wall of the scale shell 59 to the outside of the scale shell 59, and the top end of the hook 542 extends into the interior of the scale shell 59 and is bolted to a connecting block 541. The connecting block 541 is a horizontal L-shaped structure that fits the anticoagulation scale 54 and is fixed to the anticoagulation scale 54 by bolts.

[0089] Reference Fig.10 and Fig.11The damping support rod 52 is in a vertical posture, the bottom end of the damping support rod 52 extends into the interior of the body 1 and is fixedly connected to the inner wall of the body 1, the top end of the damping support rod 52 extends upward to the top of the body 1, the top end of the damping support rod 52 is coaxially fixedly connected with a horizontal bottom plate 545, the damping support rod 52 penetrates the bottom plate 545 along its own length direction, and a damping metal ring 544 bent in a wave shape is coaxially sleeved on the bottom plate 545, the bottom surface of the scale housing 59 abuts against the damping metal ring 544, the top end of the damping support rod 52 vertically penetrates the scale housing 59 and extends into the interior of the scale housing 59, the scale housing 59 is internally bolted with a pressure plate 543 abutting on the inner bottom wall of the scale housing 59, and the pressure plate 543 is bolted to the inside of the scale housing 59. 43 is fixed to the top end of the damping support rod 52 by bolts, that is, the scale housing 59 and the damping support rod 52 can rotate relative to each other, the scale housing 59 is supported on the damping support rod 52 by the aforementioned wavy-bent damping metal ring 544, the scale housing 59 always applies pressure to the damping metal ring 544, the damping metal ring 544 is always in a deformed state, the material of the damping metal ring 544 can be spring steel or elastic alloy, the damping support rod 52 enables the scale housing 59 together with the anti-coagulation scale 54 to stay at the expected height, the damping metal ring 544 enables the scale housing 59 together with the anti-coagulation scale 54 to rotate relative to the damping support rod 52, and stably stay at the current position to maintain the current posture.

[0090] Reference Fig.12 and Fig.13The inner bottom wall of the scale housing 59 has an upwardly protruding mounting platform 51, the end of the anticoagulation scale 54 away from the hook 542 is fixed on the mounting platform 51, and the protective device is located on the bottom wall of the scale housing 59 on one side of the mounting platform 51. Due to the existence of the mounting platform 51, the protective device can be hidden under the bottom surface of the anticoagulation scale 54. The protective device includes a protective bolt 547 that is threadedly connected to the scale housing 59 and extends to the inside of the scale housing 59. The head of the protective bolt 547 abuts against the bottom wall of the scale housing 59, and the threaded tail end of the protective bolt 547 vertically penetrates the bottom wall of the scale housing 59 and extends to the inside of the scale housing 59. The height of the protective bolt 547 extending into the housing 59 can be changed by rotating the protective bolt 547. The threaded tail end of the protective bolt 547 corresponds to the anticoagulant scale 54 above. When the object weighed by the anticoagulant scale 54 is within the calibrated weighing range, a gap is formed between the threaded tail end of the protective bolt 547 and the bottom surface of the anticoagulant scale 5. When the object weighed by the anticoagulant scale 54 is greater than the calibrated maximum weighable weight, the anticoagulant scale 54 bends toward the hook 542 under the action of gravity. At this time, the protective bolt 547 abuts against the bottom surface of the anticoagulant scale 54 to provide support for the anticoagulant scale 54 and prevent the anticoagulant scale 54 from being damaged by excessive force. In order to enable the protective bolt 547 to be more stably maintained at the current position and the current height, a protective cap 548 with a vertical axis is provided on the bottom wall inside the scale body shell 59. The protective cap 548 is threadedly connected to the protective bolt 547, and the protective cap 548 abuts against the inner bottom wall of the scale body shell 59. The threaded tail end of the protective bolt 547 is exposed from the top of the protective cap 548, and the protective cap 548 is used to fix the protective bolt 547 at the current position.

[0091] Reference Fig.12 and Fig.13 In order to be able to promptly discover when the object weighed by the anticoagulation scale 54 is greater than the calibrated maximum weighable weight, a downward pressure trigger alarm 546 is fixedly connected to the bottom wall inside the scale shell 59. Since the alarm of the downward pressure trigger alarm 546 needs to be pressed down for a certain distance to be triggered, the downward pressure trigger alarm 546 is located between the protective bolt 547 and the hook 542. That is, when the downward pressure trigger alarm 546 sounds an alarm, the protective bolt 547 can just provide support for the anticoagulation scale 54, thereby reducing the possibility of damage to the anticoagulation scale 54.

[0092] The anticoagulant pump 3 is fixed to the top surface of the body 1 and is located on one side of the blood sampling pump 2. The position of the anticoagulant pump 3 corresponds to the position of the anticoagulant scale 5. The anticoagulant pump 3 is connected to the control module 13 in communication, such as wireless signal communication or cable communication. The anticoagulant pump 3 is regulated by the control module 13. The control module 13 can calculate the weight of the anticoagulant injected into the pipeline 582 according to the number of rotations of the anticoagulant pump 3. Combined with the signal emitted by the anticoagulant scale 5 indicating the weight of the anticoagulant injected into the pipeline 582, a more accurate judgment can be obtained on the weight of the plasma inside the plasma container, reducing the possibility of false alarms or timeout alarms. The structure of the anticoagulant pump 3 is the same as that of the aforementioned blood sampling pump 2, so it will not be repeated.

[0093] The filter holder 15 is fixed to the side wall of the body 1 in a vertical posture and is located on one side of the partial air detector 14. The filter holder 15 is used to fix the filter on the consumables, and the filter on the consumables is used to filter the bubbles inside the blood in the pipeline. The air detector 14 is fixed on the outlet end pipeline 582 of the filter on the filter holder 15 to reduce the possibility that bubbles are generated after the blood passes through the filter on the filter holder 15 without being discovered in time, resulting in a negative impact on the blood collection process.

[0094] The pressure sensor 16 is fixed to the side wall of the body 1 and is located on one side of the filter bracket 15. The pressure sensor 16 obtains the pressure inside the pipeline 582 in real time. When the pressure inside the pipeline 582 increases or decreases, the control module 13 can choose to control the speed of the blood sampling pump 2 to decrease or increase according to the signal fed back by the pressure sensor 16. For example, when the pressure of the pipeline 582 exceeds the threshold, the speed of the blood sampling pump 2 is continuously reduced until the pressure returns to normal; when the pressure of the pipeline 582 is less than the threshold, the speed of the blood sampling pump 2 is continuously increased until the pressure returns to normal; when the pressure of the pipeline 582 is within the expected range, the blood sampling pump 2 runs at the maximum speed.

[0095] The control module 13 is fixed on the body 1 and has a touch input display extending from the top surface of the body 1 above the body 1. Through the touch input display, the operator can modify the control logic, parameters and other information of the control module 13, and during the blood collection process, perform real-time adjustment and modification according to the relevant parameters of each component displayed on the touch input display.

[0096] In this embodiment, when blood is collected, a pipeline 582 is connected to the blood collection pump 2, and a blood collection needle is provided at the end of the pipeline 582 and connected to the blood vessel of the user (i.e., the blood donor). The blood collection pump 2 is operated to transport the blood in the pipeline 582. The blood in the pipeline 582 passes through the air detector 14, the filter on the filter bracket 15, the pressure sensor 16, the blood collection pump 2, the centrifugal module 6, and the red blood cell detector 4 in sequence, and then enters the plasma container fixed on the plasma scale clamp 7. In this process, the anticoagulant fixed on the anticoagulant scale 5 is transported to the inside of the centrifugal module 6 under the action of gravity and the anticoagulant pump 3, and is centrifuged together after mixing with the blood, and finally a liquid mixed with plasma and anticoagulant is formed and enters the plasma container. Among them, the pressure sensor 16 monitors the pressure in the pipeline 582 in real time and feeds back to the control module 13, the air detector 14 detects the air bubbles in the current section pipeline 582 in real time and feeds back to the control module 13, the speed and number of rotations of the blood sampling pump 2 are fed back to the control module 13 in real time, the operation of the centrifugal module 6 is fed back to the control module 13 in real time, the red blood cell detector 4 feeds back the red blood cell detection result in the pipeline 582 to the control module 13 in real time, the plasma scale clamp 7 feeds back the weight information to the control module 13 in real time, the anticoagulant scale 5 feeds back the weight information to the control module 13 in real time, and the anticoagulant pump 3 feeds back the rotation speed and number of rotations to the control module 13 in real time. The control module 13 displays the information fed back by the above-mentioned components on the touch input display screen, and calculates whether the current blood sampling process is in the expected state based on the information fed back by the above-mentioned components. When the blood sampling process deviates from the expected state, the control module 13 alarms on the touch input display screen and can choose to control the blood sampling pump 2 and the anticoagulant pump 3 to stop. By automatically collecting and centrifuging blood, separating plasma and red blood cells for transfusion, instead of the traditional manual collection method, the burden on medical staff is reduced, the efficiency of blood collection is accelerated, and the entire blood collection process is completed in a closed circulation environment to avoid possible cross infection. At the same time, the pipeline pressure during the blood collection process is monitored in real time, and the blood collection speed is changed according to the changes in the pipeline pressure, so that the blood collection process can adapt to changes in the user's physiological state, reducing the user's discomfort during the blood collection process.

[0097] In an exemplary embodiment of the present disclosure, referring to Figure 1 , also includes an identity authentication module 11, which is communicated with the control module 13 and is used to at least obtain the user's identity information and / or biometric information.

[0098] For example, refer to Figure 1The identity verification module 11 includes a sensor fixed on the body 1 and having an NFC reading function. The identity verification module 11 is usually arranged at the intersection of the top surface and the side wall of the body 1 to facilitate the use of the user or operator. The identity verification module 11 is connected to the control module 13 in communication, such as wireless signal connection or cable communication. For example, by reading the user's ID card, the user's age and gender can be obtained. The user's height, weight, medical history and other information can also be obtained through networking. After the above information is fed back to the control module 13, the control module 13 can select a blood donation strategy adapted to the current user in the preset database, such as a specific blood collection speed, a specific blood collection volume, etc. In addition, the control module 13 can also display the user information obtained by the identity verification module 11 on a touch input display for the operator (such as a doctor, a nurse) to compare whether the blood donor is consistent with the registered information.

[0099] In this embodiment, the identity authentication module 11 can also be a fingerprint recognition device or a facial recognition device, such as an infrared fingerprint sensor, which obtains the user's identity information and historical physiological health status from the database by scanning the user's fingerprint, and displays it on a touch-input display screen for the operator to compare whether the blood donor is consistent with the registered information.

[0100] In an exemplary embodiment of the present disclosure, referring to Figure 1 , further comprising a barcode scanning module 12, which is in communication with the control module 13 and is used to obtain the barcode information of the plasma container and then match the identity information with the barcode information.

[0101] For example, refer to Figure 1 The barcode scanning module 12 includes a sensor with an infrared scanning function fixed on the body 1, for example, fixed on one side of the identity verification module 11. The barcode scanning module 12 is connected to the control module 13 in communication, such as a wireless signal connection or a cable communication. The barcode scanning module 12 feeds back the current plasma container information to the control module 13 by scanning the barcode on the plasma container. The control module 13 can match the current plasma container information with the user information obtained through the identity verification module 11 to distinguish the plasma obtained from different users. In addition, the barcode scanning module 12 can also scan the barcode on the anticoagulant container and feed it back to the control module 13 for record keeping, and the control module 13 can calculate the expected usage of the anticoagulant according to the blood donation strategy provided to the current user. When the remaining anticoagulant after the previous user completes the blood donation is not enough to support the current user's blood donation process, the control module 13 can display the prompt information on the touch input display screen, or the control module 13 can control the blood collection pump 2 to remain in the parking state and refuse to start blood collection.

[0102] In an exemplary embodiment of the present disclosure, referring to Figure 1The control module 13 is used to change the running speed of the blood sampling pump 2 according to the user's identity information and / or biological information.

[0103] For example, refer to Figure 1 , a vital sign sensor device can also be set on the user, for example, to obtain the heart rate, blood pressure, respiratory rate and other information of the current blood sampling user, and the vital sign sensor device is connected to the control module 13 by communication, such as wireless signal connection or cable communication. The vital sign sensor device transmits the user's vital sign information to the control module 13 in real time, and the control module 13 determines the user's current blood sampling strategy through a pre-built-in blood sampling scheme, and then adjusts the rotation speed of the blood sampling pump 2 and the anticoagulant pump 3 in real time.

[0104] In this embodiment, the pressure sensor 16 can feedback the pipeline pressure to the control module 13, and the control module 13 can regulate the blood sampling pump 2 according to the pipeline pressure feedback from the pressure sensor 16 and the signal feedback from the vital sign sensor device. For example: after the blood drawing starts, the pressure of the pipeline 582 is monitored in real time, and the pipeline pressure is represented by the height of the mercury column. The initial speed of the blood sampling pump 2 is set to 100rpm:

[0105] When the pressure of pipeline 582 is less than -80 mmHg, blood drawing is stopped;

[0106] When -79 mmHg<the pressure of pipeline 582<-51 mmHg, the blood sampling pump 2 is controlled to increase the operating speed. The speed of the blood sampling pump 2 increases by 100 / (-51-(-79)) rpm each time the pressure of pipeline 582 increases by 1 mmHg;

[0107] When -50 mmHg<the pressure of pipeline 582<50 mmHg, the blood sampling pump 2 operates at the initial speed of 100 rpm;

[0108] When 51 mmHg<the pressure of pipeline 582<79 mmHg, the blood sampling pump 2 is controlled to reduce the rotation speed. For every 1 mmHg increase in the pressure of pipeline 582, the speed of the blood sampling pump 2 is reduced by 100 / (79-51) rpm each time.

[0109] When the pressure of pipeline 582 is ≤80 mmHg, blood drawing is stopped.

[0110] In an exemplary embodiment of the present disclosure, referring to Figure 1 It also includes a saline scale 53 for providing a fixed position for the saline container and obtaining the weight in real time. The blood sampling pump 2 has a reverse working state. When the blood sampling pump 2 reverses, the saline flushes the centrifugal module 6 through the pipeline 582 and is delivered to the user.

[0111] For example, refer to Figure 1, the physiological saline scale 53 is fixed on the body 1 and extends from the top surface of the body 1 above the body 1. The physiological saline scale 53 and the anticoagulant scale 5 are arranged on opposite sides of the body 1. The physiological saline scale 53 is connected to the control module 13 for communication, such as wireless signal connection or cable communication. The physiological saline scale 53 feeds back the weight of the remaining physiological saline in the physiological saline container to the control module 13, so that the control module 13 can determine the weight of the physiological saline that has been used, and can judge the progress of the reinfusion process accordingly. It should be understood that the physiological saline flows into the centrifugal module 6 by gravity, so there must be a valve body on the body 1 that is controlled to start or close by the control module 13. The structure of the physiological saline scale 53 is the same as that of the aforementioned anticoagulant scale 5, so it will not be repeated.

[0112] When the blood sampling pump 2 is reversed and infused, the pressure sensor 16 can also monitor the pressure of the pipeline 582 in real time, for example, the pipeline pressure is represented by the height of a mercury column, and the initial speed of the blood sampling pump 2 is set to 100 rpm:

[0113] When the pressure of pipeline 582 is ≥260 mmHg, stop the reinfusion;

[0114] When 101 mmHg<the pressure of pipeline 582<259 mmHg, the blood sampling pump 2 is controlled to reduce the running speed. For every 1 mmHg increase in the pressure of pipeline 582, the speed of the blood sampling pump 2 is reduced by 100 / (259-101) rpm each time.

[0115] When 0 mmHg<the pressure of pipeline 582<100 mmHg, the blood sampling pump 2 runs at 100 rpm;

[0116] When the pressure of pipeline 582 is less than 0 mmHg, the backflow is stopped.

[0117] In an exemplary embodiment of the present disclosure, referring to Figure 1 The anticoagulant scale 5 has a first starting weight that is the same as the initial weight of one unit of anticoagulant. After the anticoagulant scale 5 passes through the consumables fixed with the first starting weight, the control module 13 is allowed to start the blood sampling pump 2.

[0118] For example, refer to Figure 1 The physiological saline 53 weighs a second starting weight that is the same as the initial weight of a unit of physiological saline. After the physiological saline 53 weighs a consumable with the second starting weight, the control module 13 is allowed to start the blood sampling pump 2. The first starting weight is different from the second starting weight.

[0119] In this embodiment, on the other hand, an exemplary embodiment of the present disclosure further discloses a plasma collection method, comprising the following steps:

[0120] S100, confirming the user's identity and biometric information, and matching and selecting a blood donation mode from a preset database;

[0121] S200, detecting and monitoring the user's physiological indicators in real time, and matching blood donation suggestions from a preset database according to the user's current physical condition;

[0122] S300, after the blood drawing starts, the blood sampling pump rotates to deliver the blood in the pipeline to the centrifugal module, and the anticoagulant pump delivers the anticoagulant to the centrifugal module, and after centrifugation, the anticoagulant is delivered to the plasma container; the number of revolutions of the blood sampling pump and the anticoagulant pump, as well as the weight change of the remaining anticoagulant are monitored in real time, and the whole blood volume and anticoagulant dosage in the centrifugal module are calculated; the weight of the plasma container is obtained in real time, and when the calculated result differs from the obtained weight of the plasma container by more than a threshold, the blood drawing is stopped;

[0123] S400, after blood drawing begins, real-time monitoring of the pressure in the pipeline;

[0124] When the line pressure exceeds the threshold, the speed of the blood collection pump is continuously reduced until the pressure returns to normal;

[0125] When the pipeline pressure is lower than the threshold, the speed of the blood sampling pump is continuously increased until the pressure returns to normal;

[0126] When the line pressure is within the expected range, the blood collection pump runs at the maximum speed;

[0127] After blood drawing begins, if the user's physiological indicators are abnormal, adjust the speed of the blood collection pump and the anticoagulant pump; if the user's physiological indicators still do not meet expectations, stop blood drawing or start blood transfusion;

[0128] After blood drawing begins, the pipeline at the outlet of the centrifugal module is monitored in real time, and blood drawing is stopped when red blood cell overflow is detected;

[0129] S500, after the predetermined weight of plasma is detected in the plasma container, the blood transfusion is stopped, the centrifugal module is flushed with physiological saline, and the blood collection pump reverses and retransfuses the remaining blood in the pipeline and the centrifugal module.

[0130] For example, refer to Figure 1 , step S100 specifically includes: reading the user's ID card through an identity authentication module, such as a sensor with NFC function, and obtaining the user's identity information and historical physiological health information from a database, such as historical medical conditions, which can be displayed on a touch-input display screen for operator confirmation, and selecting an adaptive blood donation strategy in the built-in database of the control module for operator confirmation.

[0131] Step S200 specifically includes: setting a vital sign sensing device on the user, for example, obtaining the heart rate, blood pressure, breathing rate and other information of the current blood sampling user, and the vital sign sensing device is connected to the control module in communication, such as wireless signal connection or cable communication. The vital sign sensing device transmits the user's vital sign information to the control module in real time. The control module determines the user's current blood sampling strategy through a pre-built-in blood sampling scheme, and then adjusts the speed of the blood sampling pump and the anticoagulant pump in real time. The pressure sensor can feedback the pipeline pressure to the control module, that is, the pressure sensor can also monitor and feedback the user's real-time physiological indicators. The control module can regulate the blood sampling pump according to the pipeline pressure feedback from the pressure sensor combined with the signal feedback from the vital sign sensing device.

[0132] Step S300 specifically includes: one end of the pipeline connected to the blood collection needle is connected to the user, the blood in the user's body enters the pipeline, and is transported to the centrifugal module under the action of the running blood collection pump. At the same time, the anticoagulant is transported to the centrifugal module under the action of the anticoagulant pump, and mixed with the blood in the pipeline inside the centrifugal module. The mixed whole blood is centrifuged in the centrifugal module to separate the plasma, and the plasma flows into the plasma container along the pipeline.

[0133] Step S400 specifically includes: after the blood drawing starts, the pressure of the pipeline is monitored in real time, the pipeline pressure is represented by the height of the mercury column, and the initial speed of the blood drawing pump is set to V (rpm):

[0134] When the line pressure is less than -80 mmHg, stop drawing blood;

[0135] When -79mmHg<line pressure<-51mmHg, control the blood sampling pump to increase the running speed. The speed of the blood sampling pump increases by V / (-51-(-79)) each time the line pressure increases by 1mmHg.

[0136] When -50mmHg<line pressure<50mmHg, the blood collection pump operates at the initial speed V;

[0137] When 51mmHg<line pressure<79mmHg, control the blood collection pump to reduce the speed. For every 1mmHg increase in line pressure, the speed of the blood collection pump is reduced by V / (79-51) each time.

[0138] When the line pressure is ≤80 mmHg, stop drawing blood.

[0139] Step S500 specifically includes: the plasma container is fixed on the plasma scale clamp, and the plasma scale clamp has a weighing function. By peeling the plasma scale clamp or presetting the weight of the empty plasma container in the control module, the weight of the plasma in the plasma container can be obtained in real time. When the weight signal fed back by the plasma scale clamp to the control module reaches a preset threshold, the control module can decide to stop the blood collection action, that is, control the blood collection pump and the anticoagulant pump to stop, and reverse the blood collection pump. At the same time, the control module can send an opening instruction to the valve body that determines whether the physiological saline enters the inside of the centrifugal module, so that the physiological saline fixed at a position higher than the centrifugal module enters the inside of the centrifugal module, that is, the inside of the centrifugal module is flushed, and the physiological saline and the whole blood after the plasma is separated can be returned to the user's body to replenish the user.

[0140] In this embodiment, in step S400: when the blood sampling pump is reversed and returned, the pressure of the pipeline is monitored in real time, the pipeline pressure is represented by the height of the mercury column, and the initial speed of the blood sampling pump is set to v (rpm):

[0141] When the line pressure is ≥260 mmHg, stop the reinfusion;

[0142] When 101mmHg<line pressure<259mmHg, control the blood collection pump to reduce the running speed. For every 1mmHg increase in line pressure, the speed of the blood collection pump is reduced by V / (259-101) each time.

[0143] When 0mmHg<line pressure<100mmHg, the blood collection pump runs at the maximum speed;

[0144] When the line pressure is less than 0 mmHg, stop the reinfusion.

[0145] The above description of the disclosed embodiments enables one skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to one skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but rather to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A plasma collection system, characterized in that: include: A blood sampling pump (2), used for conveying blood in a user's body to a centrifugal module (6) via a pipeline (582); A centrifugal module (6), used for separating plasma after centrifuging blood; A plasma weighing clamp (7), used for fixing the plasma container and obtaining the weight of the plasma container; An air detector (14), covering a portion of the pipeline (582) between the user and the centrifugal module (6), and used to monitor air bubbles in the pipeline (582); A red blood cell detector (4), covering a portion of the pipeline (582) between the centrifugal module (6) and the plasma container, and used to monitor the red blood cell concentration in the blood; an anticoagulant scale (5), used to provide a fixed position for the anticoagulant container and obtain the weight in real time; An anticoagulant pump (3), used for conveying the anticoagulant into the centrifugal module (6); A filter support (15) for supporting and replacing a filter of a portion of the pipeline (582) between the blood sampling pump (2) and the centrifugal module (6); A control module (13) is connected to the anticoagulant pump (3) and the blood sampling pump (2) for communication and is used to change the operating speed of the anticoagulant pump (3) and the blood sampling pump (2); The pressure sensor (16) is connected to the control module (13) for communication and is used to obtain the pressure of the pipeline (582) in real time. The control module (13) changes the operating speed of the anticoagulant pump (3) and the blood sampling pump (2) according to the pressure of the pipeline (582).

2. The plasma collection system according to claim 1, characterized in that: It also includes an identity verification module (11), which is communicatively connected to the control module (13) and is used to obtain at least the identity information and / or biometric information of the user.

3. The plasma collection system according to claim 2, characterized in that: It also includes a barcode scanning module (12), which is in communication with the control module (13) and is used to obtain the barcode information of the plasma container and then match the identity information with the barcode information.

4. The plasma collection system according to claim 2, characterized in that: The control module (13) is used to change the operating speed of the blood sampling pump (2) according to the identity information and / or biological information of the user.

5. The plasma collection system according to claim 1, characterized in that: It also includes a physiological saline scale (53) for providing a fixed position for the physiological saline container and obtaining the weight in real time. The blood sampling pump (2) has a reverse working state. When the blood sampling pump (2) is reversed, the physiological saline passes through the pipeline (582) to flush the centrifugal module (6) and is delivered to the user.

6. The plasma collection system according to claim 5, characterized in that: The anticoagulant scale (5) has a first starting weight that is the same as the initial weight of one unit of the anticoagulant, and the anticoagulant scale (5) allows the control module (13) to start the blood sampling pump (2) after the consumables having the first starting weight are fixed thereon.

7. The plasma collection system according to claim 6, characterized in that: The physiological saline scale (53) has a second starting weight that is the same as the initial weight of a unit of the physiological saline. The physiological saline scale (53) allows the control module (13) to start the blood sampling pump (2) after fixing the consumables with the second starting weight. The first starting weight is different from the second starting weight.

8. A method for collecting plasma, characterized in that: The plasma collection system applied to any one of claims 1 to 7 above comprises the following steps: S100, confirming the user's identity and biometric information, and matching and selecting a blood donation mode from a preset database; S200, detecting and monitoring the user's physiological indicators in real time, and matching blood donation suggestions from a preset database according to the user's current physical condition; S300, after blood drawing starts, the blood sampling pump rotates to transport the blood in the pipeline to the centrifugal module, and the anticoagulant pump transports the anticoagulant to the centrifugal module, and the anticoagulant is transported to the plasma container after centrifugation; after blood drawing starts, the number of revolutions of the blood sampling pump and the anticoagulant pump, as well as the weight change of the remaining anticoagulant are monitored in real time, and the whole blood volume and anticoagulant dosage in the centrifugal module are calculated; the weight of the plasma container is obtained in real time, and when the calculated result differs from the obtained weight of the plasma container by more than a threshold, blood drawing is stopped; S400, after blood drawing begins, real-time monitoring of the pressure in the pipeline; When the pipeline pressure exceeds the threshold, the rotation speed of the blood sampling pump is continuously reduced until the pressure returns to normal; When the pipeline pressure is less than a threshold value, the rotation speed of the blood sampling pump is continuously increased until the pressure returns to normal; When the pipeline pressure is within the expected range, the blood sampling pump operates at the maximum speed; After blood drawing starts, if the user's physiological indicators are abnormal, the rotation speeds of the blood drawing pump and the anticoagulant pump are adjusted; when the user's physiological indicators still do not meet expectations, blood drawing is stopped or blood transfusion is started; After the blood drawing starts, the pipeline at the outlet of the centrifugal module is monitored in real time, and when overflow of red blood cells is detected, the blood drawing is stopped; S500: After a predetermined weight of plasma is detected in the plasma container, blood transfusion is stopped, the centrifugal module is flushed with physiological saline, and the blood collection pump reverses and retransfuses the remaining blood in the pipeline and the centrifugal module.

9. The plasma collection method according to claim 8, characterized in that: In step S400: after the blood drawing starts, real-time monitoring of the pressure of the pipeline includes: expressing the pipeline pressure in terms of the height of a mercury column, and setting the initial speed of the blood drawing pump to V (rpm): When the line pressure is less than -80 mmHg, stop drawing blood; When -79mmHg<the pipeline pressure<-51mmHg, the blood sampling pump is controlled to increase the operating speed, and the speed of the blood sampling pump increases by V / (-51-(-79)) each time the pipeline pressure increases by 1mmHg; When -50 mmHg<the pipeline pressure<50 mmHg, the blood sampling pump operates at the initial speed V; When 51 mmHg<the pipeline pressure<79 mmHg, the blood sampling pump is controlled to reduce the rotation speed, and the speed of the blood sampling pump is reduced by V / (79-51) each time the pipeline pressure increases by 1 mmHg; When the line pressure is ≤80 mmHg, blood drawing is stopped.

10. The plasma collection method according to claim 9, characterized in that: In step S500: when the blood sampling pump is reversed and infused, real-time monitoring of the pressure of the pipeline includes: expressing the pipeline pressure in terms of the height of a mercury column, and setting the initial speed of the blood sampling pump to v (rpm): When the line pressure is ≥260 mmHg, stop the reinfusion; When 101 mmHg<the pipeline pressure<259 mmHg, the blood sampling pump is controlled to reduce the operating speed, and the speed of the blood sampling pump is reduced by V / (259-101) each time the pipeline pressure increases by 1 mmHg; When 0 mmHg<line pressure<100 mmHg, the blood sampling pump operates at the maximum speed; When the line pressure is less than 0 mmHg, stop the reinfusion.

Images