Deodorizing dressing and application thereof

Abstract

The invention provides a deodorization dressing and application thereof. The deodorization dressing comprises a thin film layer, a deodorization layer wrapped in a hydrophilic material, an organic silicon wound contact layer and a protective layer which are sequentially arranged in a stacked mode. The deodorization layer is prepared from the following components in parts by weight: 1 to 8 parts of activated carbon, 5 to 10 parts of sodium polyacrylate, 0.1 to 1 part of deodorant, 0.05 to 0.3 part of antibacterial agent and 0.1 to 1 part of acid-base regulator. Compared with the prior art, the deodorizing dressing provided by the invention has the advantages that the deodorizing effect is obviously improved, the wrapping technology is utilized, the condition of fiber breakage and residue is avoided, the use safety is effectively improved, and compared with the scheme of the prior art, the deodorizing dressing has obvious advantages.

Description

Technical Field

[0001] The invention belongs to the technical field of medical devices, and in particular relates to a deodorizing dressing and an application thereof. Background Art

[0002] In clinical practice, some infectious or chronic wounds will have exudate, and medical staff usually choose vaseline gauze dressings for exudate drainage and covering care, such as burn wounds, anorectal surgery wounds, pressure sores, and donor site wounds. This type of dressing also has the performance of preventing gauze from adhering to the wound, avoiding secondary damage to the wound during dressing changes, and is conducive to the growth of fresh granulation tissue. However, the healing time of such chronic wounds or infected wounds is usually relatively long, which not only causes physical pain to the patient, but also the odor often emitted by the wound also brings psychological burden and distress to the injured. The use of traditional vaseline dressings can no longer solve this problem. For this reason, people have developed other deodorizing dressings, but among the currently available dressings, the dressings that are advertised to have a deodorizing function are mostly made of activated carbon fiber materials. Because the activated fiber is fragile and has a very low specific surface area, its use effect and convenience are limited, and it cannot be applied on a large scale. At the same time, during the application process, there is a phenomenon that the fiber breaks and remains in the wound, causing certain safety hazards.

[0003] CN201911402417.X discloses a highly comfortable, breathable deodorizing dressing, including gauze and an effective ingredient, which is measured by weight as follows: 100 parts of component A, 0.1-10 parts of bismuth tribromophenate, and 1-10 parts of cyclodextrin; the component A, measured by weight, includes the following ingredients: 70-90 parts of vaseline and 8.9-10 parts of liquid paraffin. The product has good air permeability, a low softening point, does not require preheating when used, and has a good sense of comfort for patients when used at a lower temperature. It can also permanently cover up and absorb the unpleasant odor generated during wound healing, and has good application prospects. However, this technical solution still has the problem of long healing time involved in vaseline dressings.

[0004] CN202221639847.0 discloses a new type of highly absorbent deodorizing dressing, including a highly absorbent layer made of a highly absorbent polymer, which can absorb a large amount of wound exudate, thereby effectively reducing the secondary infection of the wound by bacteria in the exudate and reducing the impact of the wound on the patient. However, the effect of this solution mainly involves absorbing wound exudate, and the deodorizing effect is not obvious.

[0005] Since the existing technology cannot effectively solve the problems of odor and safety, how to provide a dressing that can effectively remove wound odor and is highly safe has become an urgent problem to be solved. Summary of the invention

[0006] In view of the shortcomings of the prior art, the purpose of the present invention is to provide a deodorizing dressing and its application. The deodorizing dressing provided by the present invention significantly improves the deodorizing effect compared with the prior art, and utilizes the wrapping technology to avoid the situation of fiber breakage and residue, effectively improving the safety of use, which has significant advantages over the prior art solutions.

[0007] In order to achieve the purpose of the invention, the present invention adopts the following technical solutions:

[0008] In one aspect, the present invention provides a deodorizing dressing, comprising a film layer, a deodorizing layer wrapped in a hydrophilic material, a silicone wound contact layer, and a protective layer stacked in sequence;

[0009] The deodorizing layer comprises, by weight, 1-8 parts of activated carbon, 5-10 parts of sodium polyacrylate (SAP), 0.1-1 parts of deodorant, 0.05-0.3 parts of antibacterial agent and 0.1-1 parts of acid-base regulator.

[0010] Among them, the number of activated carbon parts can be 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts or 8 parts, the number of sodium polyacrylate parts can be 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts, the number of deodorants can be 0.1 parts, 0.2 parts, 0.3 parts, 0.4 parts, 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, 0.9 parts or 1 parts, the number of antibacterial agents can be 0.05 parts, 0.1 parts, 0.15 parts, 0.2 parts, 0.25 parts or 0.3 parts, the number of acid-base regulators can be 0.1 parts, 0.2 parts, 0.3 parts, 0.4 parts, 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, 0.9 parts or 1 parts, but are not limited to the values ​​listed above, and other values ​​not listed within the above numerical range are equally applicable.

[0011] The above scheme adopts a compound of activated carbon, sodium polyacrylate, antibacterial agent, deodorant and acid-base regulator, which works synergistically to effectively absorb wound exudate, kill bacteria, remove odor, and improve the deodorization effect of the product; at the same time, wrapping the deodorization layer with hydrophilic material can prevent the fibers in the deodorization layer from breaking and remaining in the wound, effectively improving the safety of the product, and having significant advantages over the existing technical solutions.

[0012] Preferably, the activated carbon comprises activated carbon particles and / or activated carbon fibers.

[0013] Preferably, the particle size of the activated carbon particles is not less than 80 mesh.

[0014] Preferably, the sodium polyacrylate comprises sodium polyacrylate particles and / or sodium polyacrylate fibers.

[0015] Preferably, the particle size of the sodium polyacrylate particles is not less than 80 mesh.

[0016] Preferably, the antibacterial agent comprises any one of an inorganic silver ion compound, PHMB (polyhexamethylene hydrochloride), CHG (chlorhexidine gluconate) or an inorganic zinc ion compound, or a combination of at least two thereof.

[0017] Preferably, the deodorant comprises any one of citric acid, tartaric acid, zinc ricinoleate or fatty alcohol methacrylate or a combination of at least two thereof, preferably a combination of citric acid and fatty alcohol methacrylate.

[0018] The above specific deodorant combination can more effectively improve the deodorizing effect of the product compared to other options.

[0019] Preferably, the acid-base regulator comprises sodium citrate and / or potassium phosphate.

[0020] Preferably, the hydrophilic material includes any one of polyurethane foam, hydrophilic non-woven fabric or hydrophilic woven fabric, or a combination of at least two of them.

[0021] Preferably, the silicone wound contact layer comprises silicone gel.

[0022] Preferably, the protective layer comprises a PE film or a composite material comprising a PE film.

[0023] Preferably, the film layer and the hydrophilic material are adhered by a pressure-sensitive adhesive.

[0024] Preferably, the deodorizing layer is prepared by a method comprising the following steps:

[0025] The activated carbon, sodium polyacrylate, antibacterial agent, deodorant, acid-base regulator and adhesive are mixed and coated, and then dried to obtain the deodorizing layer;

[0026] Alternatively, activated carbon, sodium polyacrylate, antibacterial agent, deodorant, acid-base regulator and adhesive are applied on the surface of wood pulp fiber and / or chemical fiber to obtain a non-woven deodorant layer.

[0027] Preferably, the ratio of the total mass of the activated carbon, sodium polyacrylate, antibacterial agent, deodorant and acid-base regulator to the mass of the adhesive is (5-10):(1-4), wherein the total mass of the activated carbon, sodium polyacrylate, antibacterial agent, deodorant and acid-base regulator can be 5, 6, 7, 8, 9 or 10, and the mass of the adhesive can be 1, 1.5, 2, 2.5, 3, 3.5 or 4, etc., but are not limited to the values ​​listed above, and other values ​​not listed within the above numerical range are also applicable.

[0028] On the other hand, the present invention also provides the use of the deodorizing dressing as described above in the preparation of medical wound dressing.

[0029] Compared with the prior art, the present invention has the following beneficial effects:

[0030] The present invention provides a deodorizing dressing, which adopts a compound of activated carbon, sodium polyacrylate, an antibacterial agent, a deodorant and an acid-base regulator, and the synergistic effect of the five ingredients can effectively absorb wound exudate, kill bacteria, remove odor, and improve the deodorizing effect of the product; at the same time, wrapping the deodorizing layer with a hydrophilic material can prevent the fibers in the deodorizing layer from breaking and remaining in the wound, thereby effectively improving the safety of the product, and having significant advantages over the existing technical solutions. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 It is a schematic diagram of the structure of the deodorant dressing provided in Examples 1-3. DETAILED DESCRIPTION

[0032] The technical solution of the present invention is further described below by specific implementation methods. It should be understood by those skilled in the art that the embodiments are only to help understand the present invention and should not be regarded as specific limitations of the present invention.

[0033] In the following examples, sodium polyacrylate particles were purchased from Sumitomo, Japan;

[0034] Methacrylate fatty alcohol was purchased from Sinopharm Group;

[0035] The polyurethane material was purchased from Boruis.

[0036] Example 1

[0037] This embodiment provides a deodorizing dressing, the structure of which is as follows: Figure 1 As shown (1 is a polyurethane film, 2 is a pressure-sensitive adhesive, 3 is a deodorizing layer, 4 is a hydrophilic material (polyurethane foam), 5 is a silicone wound contact layer (perforated silicone gel), and 6 is a protective layer (PE film)).

[0038] The preparation method is as follows:

[0039] Activated carbon particles of 80 mesh, SAP particles of 100 mesh, a deodorant (citric acid: methacrylate fatty alcohol mass ratio of 4:1), an antibacterial agent (sodium zirconium phosphate silver), and an acid-base regulator (sodium citrate) (weight parts are 3 parts, 7 parts, 0.5 parts, 0.1 parts, and 0.5 parts, respectively) are mixed, and the mixed particles are mixed with aminum glue at a mass ratio of 7:3. After coating and drying, a deodorizing layer of 200 g / m2 is obtained.

[0040] Then, the deodorizing layer is wrapped in two layers of polyurethane hydrophilic foam, the four sides are pressed together by high frequency, and the organic silicon wound contact layer, the protective layer, the pressure-sensitive adhesive and the polyurethane film are coated and pasted respectively according to the structure to obtain the deodorizing dressing.

[0041] Example 2

[0042] This embodiment provides a deodorizing dressing, the structure of which is as follows: Figure 1 As shown (1 is a polyurethane film, 2 is a pressure-sensitive adhesive, 3 is a deodorizing layer, 4 is a hydrophilic material (polyurethane foam), 5 is a silicone wound contact layer (perforated silicone gel), and 6 is a protective layer (PE film)).

[0043] The preparation method is as follows:

[0044] Activated carbon particles of 80 mesh, SAP particles of 100 mesh, a deodorant (citric acid: methacrylate fatty alcohol mass ratio of 2:1), an antibacterial agent (sodium zirconium phosphate silver), and an acid-base regulator (sodium citrate) (weight parts are 1 part, 5 parts, 0.1 parts, 0.05 parts, and 0.1 parts, respectively) are mixed, and the mixed particles are mixed with aminum glue at a mass ratio of 5:4. After coating and drying, a deodorizing layer of 200 g / m2 is obtained.

[0045] Then, the deodorizing layer is wrapped in two layers of polyurethane hydrophilic foam, the four sides are pressed together by high frequency, and the organic silicon wound contact layer, the protective layer, the pressure-sensitive adhesive and the polyurethane film are coated and pasted respectively according to the structure to obtain the deodorizing dressing.

[0046] Example 3

[0047] This embodiment provides a deodorizing dressing, the structure of which is as follows: Figure 1 As shown (1 is a polyurethane film, 2 is a pressure-sensitive adhesive, 3 is a deodorizing layer, 4 is a hydrophilic material (polyurethane foam), 5 is a silicone wound contact layer (perforated silicone gel), and 6 is a protective layer (PE film)).

[0048] The preparation method is as follows:

[0049] Activated carbon particles of 80 mesh, SAP particles of 100 mesh, a deodorant (citric acid: methacrylic acid fatty alcohol mass ratio of 1:1), an antibacterial agent (sodium zirconium phosphate silver), and an acid-base regulator (potassium phosphate) (8 parts, 10 parts, 1 part, 0.3 parts, and 1 part by weight, respectively) are mixed, and the mixed particles are mixed with aminum glue at a mass ratio of 10:1. After coating and drying, a deodorant layer of 200 g / m2 is obtained.

[0050] Then, the deodorizing layer is wrapped in two layers of polyurethane hydrophilic foam, the four sides are pressed together by high frequency, and the organic silicon wound contact layer, the protective layer, the pressure-sensitive adhesive and the polyurethane film are coated and pasted respectively according to the structure to obtain the deodorizing dressing.

[0051] Example 4

[0052] This embodiment provides a deodorizing dressing, and the preparation method is consistent with that of embodiment 1 except that citric acid is not included and a portion allocated to methacrylate fatty alcohol is reduced.

[0053] Example 5

[0054] This embodiment provides a deodorizing dressing, and the preparation method is consistent with that of embodiment 1 except that methacrylate fatty alcohol is not included and a reduced portion is allocated to citric acid.

[0055] Example 6

[0056] This embodiment provides a deodorizing dressing. The preparation method is the same as that of Embodiment 1 except that citric acid is replaced by an equal amount of tartaric acid.

[0057] Comparative Example 1

[0058] This comparative example provides a deodorizing dressing, and the preparation method is consistent with Example 1 except that the activated carbon particles are not included and the reduced part is proportionally allocated to SAP particles, deodorant, antibacterial agent, and acid-base regulator.

[0059] Comparative Example 2

[0060] This comparative example provides a deodorizing dressing, and the preparation method is consistent with Example 1 except that SAP particles are not included and the reduced part is proportionally allocated to activated carbon particles, deodorant, antibacterial agent, and acid-base regulator.

[0061] Comparative Example 3

[0062] This comparative example provides a deodorizing dressing, and the preparation method is consistent with Example 1 except that the deodorant is not included and the reduced part is distributed proportionally to SAP particles, activated carbon particles, antibacterial agent, and acid-base regulator.

[0063] Comparative Example 4

[0064] This comparative example provides a deodorizing dressing, and the preparation method is consistent with Example 1 except that the antibacterial agent is not included and the reduced part is proportionally distributed to SAP particles, deodorizing agent, activated carbon particles, and acid-base regulator.

[0065] Comparative Example 5

[0066] This comparative example provides a deodorizing dressing, and the preparation method is consistent with Example 1 except that the acid-base regulator is not included and the reduced part is proportionally distributed to SAP particles, deodorant, antibacterial agent, and activated carbon particles.

[0067] Effect test:

[0068] The products provided in Examples 1-6 and Comparative Examples 1-5 and commercially available deodorant dressings were tested for biocompatibility (test reference ISO10993) and deodorization performance (test reference GB / T 33610-2019, with ammonia water as the test object).

[0069] The results are as follows:

[0070]

[0071] From the above data, it can be found that the product provided by the present invention can effectively remove wound odor, avoid the situation of fiber breakage and residual wound, and has high safety; by comparing Examples 1-6, it can be found that the present invention can further improve the deodorizing effect of the product by selecting a specific deodorant and coordinating with other raw materials; by comparing Example 1 and Comparative Examples 1-5, it can be found that the present invention adopts a compound of activated carbon, sodium polyacrylate, antibacterial agent, deodorant and acid-base regulator, which can effectively absorb wound exudate, kill bacteria, remove odor, and improve the deodorizing effect of the product.

[0072] The applicant declares that the present invention illustrates the deodorant dressing and its application through the above-mentioned embodiments, but the present invention is not limited to the above-mentioned embodiments, that is, it does not mean that the present invention must rely on the above-mentioned embodiments to be implemented. Those skilled in the art should understand that any improvement of the present invention, equivalent replacement of various raw materials of the product of the present invention, addition of auxiliary components, selection of specific methods, etc., all fall within the protection scope and disclosure scope of the present invention.

[0073] The preferred embodiments of the present invention are described in detail above. However, the present invention is not limited to the specific details in the above embodiments. Within the technical concept of the present invention, a variety of simple modifications can be made to the technical solution of the present invention, and these simple modifications all belong to the protection scope of the present invention.

[0074] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the present invention will not further describe various possible combinations.

Claims

1. A deodorant dressing, characterized in that: The deodorizing dressing comprises a film layer, a deodorizing layer wrapped in a hydrophilic material, an organic silicon wound contact layer and a protective layer which are stacked in sequence; The deodorizing layer comprises, by weight, 1-8 parts of activated carbon, 5-10 parts of sodium polyacrylate, 0.1-1 parts of deodorant, 0.05-0.3 parts of antibacterial agent and 0.1-1 parts of acid-base regulator.

2. The deodorant dressing according to claim 1, characterized in that The activated carbon includes activated carbon particles and / or activated carbon fibers; The sodium polyacrylate includes sodium polyacrylate particles and / or sodium polyacrylate fibers.

3. The deodorant dressing according to claim 2, characterized in that The particle size of the activated carbon particles is not less than 80 mesh; The particle size of the sodium polyacrylate particles is not less than 80 meshes.

4. The deodorant dressing according to claim 3, characterized in that The antibacterial agent includes any one of an inorganic silver ion compound, PHMB, CHG or an inorganic zinc ion compound or a combination of at least two thereof.

5. The deodorant dressing according to claim 4, characterized in that The deodorant comprises any one of citric acid, tartaric acid, zinc ricinoleate or fatty alcohol methacrylate or a combination of at least two thereof; The acid-base regulator includes sodium citrate and / or potassium phosphate.

6. The deodorant dressing according to claim 5, characterized in that The deodorant is a combination of citric acid and fatty alcohol methacrylate.

7. The deodorant dressing according to claim 6, characterized in that The hydrophilic material includes any one of polyurethane foam, hydrophilic non-woven fabric or hydrophilic woven fabric, or a combination of at least two thereof; The silicone wound contact layer comprises silicone gel; The protective layer comprises a PE film or a composite material comprising a PE film; The film layer and the hydrophilic material are adhered to each other through a pressure-sensitive adhesive.

8. The deodorant dressing according to claim 7, characterized in that The deodorizing layer is prepared by a method comprising the following steps: The activated carbon, sodium polyacrylate, antibacterial agent, deodorant, acid-base regulator and adhesive are mixed and coated, and then dried to obtain the deodorizing layer; Alternatively, activated carbon, sodium polyacrylate, antibacterial agent, deodorant, acid-base regulator and adhesive are applied on the surface of wood pulp fiber and / or chemical fiber to obtain a non-woven deodorant layer.

9. The deodorant dressing according to claim 8, characterized in that The ratio of the total mass of the activated carbon, sodium polyacrylate, antibacterial agent, deodorant, and acid-base regulator to the mass of the adhesive is (5-10):(1-4).

10. Use of the deodorizing dressing according to any one of claims 1 to 9 in the preparation of medical wound dressing.

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