Traditional Chinese medicine composition for benefiting intestines and moistening lung and application of traditional Chinese medicine composition in food

Abstract

The invention provides a traditional Chinese medicine composition for benefiting intestines and moistening lung. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 10 to 15 parts of fructus cannabis, 9 to 15 parts of fructus momordicae, 9 to 12 parts of folium eriobotryae, 6 to 12 parts of radix ophiopogonis, 6 to 10 parts of radix polygonati officinalis, 6 to 8 parts of radix asparagi, 4 to 8 parts of elderberry, 4 to 6 parts of dendrobium officinale, 4 to 6 parts of herba cistanche, 2 to 6 parts of liquorice root, 2 to 5 parts of pummelo peel, 2 to 5 parts of radix astragali seu hedysari, 0.2 to 0.5 part of sugarcane polyphenol, 0.1 to 0.3 part of VC and 0.001 to 0.002 part of dihydroquercetin. Prebiotics such as galactomannan, fructo-oligosaccharide, xylooligosaccharide and the like, and auxiliary materials such as sorbitol, silicon dioxide, magnesium stearate and the like are selectively added. The prepared traditional Chinese medicine composition can be prepared into drinks, ointments, granules, tablets, solid drinks and the like, has multiple effective components and high extraction rate, and has good intestine-benefiting and lung-moistening effects.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine compositions, and specifically relates to a traditional Chinese medicine composition for benefiting intestines and moistening lungs and application thereof in food. Background Art

[0002] Drugs that are collected, processed, and prepared according to traditional Chinese medical theory, explained in terms of their mechanism of action, and guided in their clinical application are collectively referred to as Chinese medicine. The reason why drugs can be used to treat diseases is that various drugs have certain characteristics and functions, which our ancestors called the bias of drugs. The properties and performance of drugs related to efficacy are collectively referred to as drug properties, which include the material basis for the drug to exert its efficacy and the effects manifested during the treatment process. It is a high-level summary of the properties and functions of drugs. The theory that studies the mechanism of the formation of drug properties and the laws of their application is called the theory of drug properties, and its basic contents include the four qi and five flavors, rising and falling, meridians, toxicity and non-toxicity, compatibility, and taboos.

[0003] In traditional Chinese medicine theory, the intestines are closely related to the lungs, spleen and other internal organs. Traditional Chinese medicine believes that "the lungs and the large intestine are the exterior and interior of each other", that is, the lungs control qi, and the large intestine controls waste, and the two are connected through meridians. Therefore, regulating lung qi can help improve the function of the large intestine. In addition, the spleen and stomach are the foundation of acquired constitution, responsible for transporting water and grain. Weak spleen and stomach will affect the normal function of the intestines, leading to problems such as indigestion and constipation. When treating intestinal problems, traditional Chinese medicine often starts with regulating the spleen and stomach, using Chinese medicine that strengthens the spleen and replenishes qi and moisturizes the intestines for treatment.

[0004] As for strengthening the spleen, removing dampness and moistening the lungs, there are few studies on the preparation methods. The traditional preparation method is to mix and boil various medicinal materials. Although it is relatively simple, it also has problems such as extensive process, few effective ingredients and poor drug effects. Summary of the invention

[0005] The purpose of the present invention is to provide a Chinese medicine composition for benefiting the intestines and moistening the lungs and a preparation method thereof. By using hemp seeds, momordica grosvenori, loquat leaves, ophiopogon japonicus, polygonatum odoratum, asparagus cochinchinensis, elderberry and other main ingredients and optimizing and adjusting the preparation process, a Chinese medicine product with the properties of benefiting the intestines, clearing the lungs and protecting the lungs is obtained. The Chinese medicine product can be made into drinks, ointments, granules, tablets, solid drinks and the like.

[0006] In order to achieve the above object, the present invention provides the following technical solutions: A Chinese medicine composition for benefiting the intestines and moistening the lungs comprises the following components in parts by weight: 10-15 parts of hemp seeds, 9-15 parts of momordica grosvenori, 9-12 parts of loquat leaves, 6-12 parts of ophiopogon japonicus, 6-10 parts of polygonatum odoratum, 6-8 parts of asparagus cochinchinensis, 4-8 parts of elderberry, 4-6 parts of dendrobium officinale, 4-6 parts of cistanche deserticola, 2-6 parts of liquorice, 2-5 parts of tangerine peel, 2-5 parts of astragalus, 0.2-0.5 parts of sugarcane polyphenols, 0.1-0.3 parts of VC, and 0.001-0.002 parts of dihydroquercetin.

[0007] Furthermore, it also includes one or a mixture of 0.3-0.6 parts of galactomannan, 0.1-0.3 parts of oligofructose, 0.2-0.5 parts of oligoxylose, 0.3-0.6 parts of sorbitol, 0.05-0.15 parts of silicon dioxide and 0.08-0.16 parts of magnesium stearate.

[0008] A Chinese medicine composition for benefiting intestines and moistening lungs comprises the following steps: S1: 10-15 parts of hemp seeds, 9-15 parts of momordica grosvenori, 9-12 parts of loquat leaves, 6-12 parts of ophiopogon japonicus, 6-10 parts of polygonatum odoratum, 6-8 parts of asparagus cochinchinensis, 4-7 parts of elderberry, 2-8 parts of liquorice, 2-5 parts of tangerine peel, 2-5 parts of astragalus, 0.2-0.5 parts of sugarcane polyphenols, 0.1-0.3 parts of VC, and 0.001-0.002 parts of dihydroquercetin are ground to obtain a ground mixture; S2: subjecting the crushed mixture in step S1 to ultrasonic countercurrent extraction; S3: separating the extract in step S2 into solid and liquid, taking the liquid phase and adding 0.3-0.6 parts of galactomannan, 0.1-0.3 parts of oligofructose, 0.2-0.5 parts of oligoxylose, 0.3-0.6 parts of sorbitol, 0.05-0.15 parts of silicon dioxide and 0.08-0.16 parts of magnesium stearate, stirring and reacting for 40-60 minutes; then adding 10-20 parts of ethanol solution, and continuing to stir and react for 55-75 minutes; S4: filtering and concentrating the mixture obtained in step S3 to obtain the intestinal-benefiting and lung-moistening Chinese medicine composition.

[0009] Furthermore, in step S1, the components of the Chinese medicine raw materials are mixed and sent to an ultrafine grinding device to be ground into a central particle size of 5-10 μm.

[0010] Furthermore, in the ultrasonic countercurrent extraction in step S2, a mixture of ammonia water and ethanol is used as the solvent, the solid-liquid ratio of the Chinese medicine raw material component and the solvent is 1g:12-20ml, and the extraction is carried out for 2-4h to obtain a crude extract; the crude extract is then concentrated to obtain a concentrated solution, which is then centrifuged to obtain a Chinese medicine component extract.

[0011] Furthermore, the volume ratio of ammonia water to ethanol is 1-3:1; the vacuum concentration temperature is 35-45°C, the vacuum degree is 0.06-0.07MPa, and the time is 10-20min.

[0012] Furthermore, the centrifugal treatment is performed at a speed of 800-1000 rps and a time of 5-10 min.

[0013] Furthermore, step S3 is specifically as follows: separating the extract in step S2 into a solid and liquid phase, taking the liquid phase and adding 0.3-0.6 parts of galactomannan, 0.1-0.3 parts of oligofructose, 0.2-0.5 parts of oligoxylose, 0.3-0.6 parts of sorbitol, 0.05-0.15 parts of silicon dioxide and 0.08-0.16 parts of magnesium stearate, stirring and reacting at a temperature of 30-40°C at a rate of 600-800r / min for 40-60min; then adding 10-20 parts of ethanol solution, and continuing to stir and react for 55-75min.

[0014] Furthermore, step S4 is specifically as follows: the concentration temperature is 55-65° C., the vacuum degree is 0.04-0.06 MPa, and the concentration time is 25-35 min.

[0015] The above-mentioned Chinese medicine composition is applied to foods such as beverages, ointments, granules, tablets, solid beverages, etc.

[0016] Hemp seeds come from the seeds of cannabis plant varieties that contain no or very low amounts of tetrahydrocannabinol (THC). The main ingredients include unsaturated fatty acids: such as linoleic acid (Omega-6) and α-linolenic acid (Omega-3), which are beneficial to cardiovascular health; protein: rich in essential amino acids; minerals: such as magnesium, iron, zinc, etc.; vitamins: such as vitamin E, which has antioxidant effects.

[0017] Monk fruit, also known as monk fruit, lahan fruit, false bitter melon, etc., is a plant of the Cucurbitaceae family native to southern China. Its fruit is widely used for its sweetness and medicinal value, especially in traditional Chinese medicine and traditional diet therapy. The main ingredients include mogrosides: this is the main active ingredient of monk fruit, with extremely high sweetness (about 300 times that of sucrose), but extremely low in calories, so it is often used to make natural sweeteners; polysaccharides: have immunomodulatory and antioxidant effects; flavonoids: such as quercetin, kaempferol, etc., have anti-inflammatory and antioxidant effects; vitamin C: helps to enhance immunity; minerals: such as potassium, calcium, magnesium, etc.

[0018] Loquat is a small evergreen tree native to southern China and now widely distributed in temperate regions of Asia, Europe and North America. Loquat leaves are oblong or obovate, leathery, smooth and shiny on the surface, and densely covered with velvet on the back. The main ingredients include amygdalin: it has antitussive and expectorant effects; flavonoids: such as quercetin and kaempferol, which have antioxidant and anti-inflammatory effects; triterpenoids: such as ursolic acid, which have anti-inflammatory and antibacterial effects; volatile oils: have an aromatic smell and help relieve respiratory symptoms; organic acids: such as malic acid and citric acid, which help regulate gastrointestinal function.

[0019] Ophiopogon japonicus is a perennial evergreen herb, mainly distributed in the areas south of the Yangtze River in China, such as Zhejiang, Jiangsu, Anhui, etc. Its underground part has fleshy tubers, which are spindle-shaped, yellow-white on the surface, soft in texture, white inside, and sweet and slightly bitter in taste; the main ingredients include steroidal saponins: such as ophiopogon saponins A, B, C, etc., which have anti-inflammatory, antioxidant, and immunomodulatory effects; polysaccharides: such as ophiopogon polysaccharides, which have the effects of enhancing immunity and antioxidant; flavonoids: such as quercetin, kaempferol, etc., which have antioxidant and anti-inflammatory effects; amino acids: such as aspartic acid, arginine, etc., which help nourish the body; vitamins and minerals: such as B vitamins, potassium, calcium, magnesium, etc., which help maintain normal body functions.

[0020] Polygonatum odoratum is a perennial herb, mainly distributed in Northeast China, North China, East China and Southwest China. Its rhizome is long cylindrical, with a light yellow or yellow-white surface, a soft texture, a white interior, and a sweet and slightly cold taste. The main ingredients include polysaccharides: such as Polygonatum odoratum polysaccharide, which has the effects of enhancing immunity and anti-oxidation; steroidal saponins: such as Polygonatum odoratum saponin, which has anti-inflammatory, antioxidant, and immunomodulatory effects; flavonoids: such as quercetin, kaempferol, etc., which have antioxidant and anti-inflammatory effects; amino acids: such as aspartic acid, arginine, etc., which help nourish the body; vitamins and minerals: such as B vitamins, potassium, calcium, magnesium, etc., which help maintain normal body functions.

[0021] Compared with the prior art, the advantages and beneficial effects of the present invention are: The invention takes ophiopogon japonicus, polygonatum odoratum, asparagus cochinchinensis, loquat leaf, hemp seed, momordica grosvenori, liquorice, tangerine peel, astragalus and other ingredients as main components, and with the synergistic effect of dihydroquercetin, sugarcane polyphenols, elderberry, VC and other ingredients, and is supplemented with auxiliary materials such as prebiotics, sorbitol, silicon dioxide, magnesium stearate and other auxiliary materials, which together play the roles of moistening the lungs, benefiting the intestines, regulating qi and the like; by adopting ultrasonic countercurrent extraction, the content of effective ingredients of traditional Chinese medicine and the extraction efficiency are better, and the obtained traditional Chinese medicine composition has better effect. DETAILED DESCRIPTION

[0022] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0023] Example 1 This embodiment provides a method for preparing a Chinese medicine composition for benefiting the intestines and moistening the lungs, comprising the following steps: S1: Take 10g of hemp seed, 9g of momordica grosvenori, 9g of loquat leaf, 6g of ophiopogon japonicus, 6g of polygonatum odoratum, 6g of asparagus cochinchinensis, 4g of elderberry, 4g of dendrobium officinale, 4g of cistanche deserticola, 2g of liquorice, 2g of tangerine peel, 2g of astragalus, 0.2g of sugarcane polyphenol, 0.1g of VC, and 0.001g of dihydroquercetin, mix them, and send them to an ultrafine grinding device to grind them to a central particle size of 5-10μm to obtain a grinded material; S2: Using a mixed solution of ammonia water and ethanol in a volume ratio of 1:1 as solvent, the crushed material in step S1 and the solvent are mixed according to a solid-liquid ratio of 1g:12ml, and extracted at a temperature of 85°C for 2h to obtain a crude extract; at a vacuum degree of 0.06MPa and a temperature of 35°C, the crude extract is concentrated to 1 / 4 of the original solution; centrifuged at a speed of 800rps for 5min, and a Chinese medicine component extract is obtained by separation; S3: The extract in step S2 is separated into solid and liquid, and 0.3 g galactomannan, 0.1 g fructooligosaccharide, 0.2 g xylo-oligosaccharide, 0.3 g sorbitol, 0.05 g silicon dioxide and 0.08 g magnesium stearate are added to the liquid phase, and the mixture is stirred at 600 r / min at a temperature of 30° C. for 40 min; 10 g ethanol solution is then added, and the mixture is stirred and reacted for 55 min; S4: Filter the mixture obtained in step S3, and concentrate it to 1 / 3 of the original solution at a vacuum degree of 0.04 MPa and a temperature of 55° C., thereby obtaining the intestinal-benefiting and lung-moistening Chinese medicine composition.

[0024] Example 2 This embodiment provides a method for preparing a Chinese medicine composition for benefiting the intestines and moistening the lungs, comprising the following steps: S1: Take 15g of hemp seed, 15g of momordica grosvenori, 12g of loquat leaf, 12g of ophiopogon japonicus, 10g of polygonatum, 8g of asparagus cochinchinensis, 8g of elderberry, 6 parts of dendrobium officinale, 6 parts of cistanche deserticola, 6g of liquorice, 5g of tangerine peel, 5g of astragalus, 0.5g of sugarcane polyphenol, 0.3g of VC, and 0.002g of dihydroquercetin, mix them and send them to ultrafine grinding equipment, grind them to a central particle size of 5-10μm, and obtain a grind; S2: Using a mixed solution of ammonia water and ethanol in a volume ratio of 3:1 as solvent, the crushed material in step S1 and the solvent are mixed according to a solid-liquid ratio of 1g:20ml, and extracted at a temperature of 95°C for 4h to obtain a crude extract; at a vacuum degree of 0.07MPa and a temperature of 45°C, the crude extract is concentrated to 1 / 4 of the original solution; centrifuged at a speed of 1000rps for 10min, and a Chinese medicine component extract is obtained by separation; S3: separating the extract in step S2 into solid and liquid, taking the liquid phase, adding 0.6 g galactomannan, 0.3 g fructooligosaccharide, 0.5 g xylo-oligosaccharide, 0.6 g sorbitol, 0.15 g silicon dioxide and 0.16 g magnesium stearate, stirring at 40°C at a speed of 800 r / min for 60 min; then adding 20 g ethanol solution, and continuing stirring for 75 min; S4: Filter the mixture obtained in step S3, and concentrate it to 1 / 3 of the original solution at a vacuum degree of 0.06 MPa and a temperature of 65° C., thereby obtaining the intestinal-benefiting and lung-moistening Chinese medicine composition.

[0025] Example 3 This embodiment provides a method for preparing a Chinese medicine composition for benefiting the intestines and moistening the lungs, comprising the following steps: S1: Take 12g of hemp seed, 13g of momordica grosvenori, 11g of loquat leaf, 8g of ophiopogon japonicus, 8g of polygonatum odoratum, 7g of asparagus cochinchinensis, 5g of elderberry, 5g of dendrobium officinale, 5g of cistanche deserticola, 5g of liquorice, 4g of tangerine peel, 3g of astragalus, 0.4g of sugarcane polyphenol, 0.2g of VC, and 0.0015g of dihydroquercetin, mix them, and send them to an ultrafine grinding device to grind them to a central particle size of 5-10μm to obtain a grinded material; S2: Using a mixed solution of ammonia water and ethanol in a volume ratio of 2:1 as solvent, the crushed material in step S1 and the solvent are mixed according to a solid-liquid ratio of 1g:18ml, and extracted at a temperature of 90°C for 3h to obtain a crude extract; at a vacuum degree of 0.065MPa and a temperature of 42°C, the crude extract is concentrated to 1 / 4 of the original solution; centrifuged at a speed of 900rps for 7min, and a Chinese medicine component extract is obtained by separation; S3: Separate the extract in step S2 into solid and liquid, take the liquid phase, add 0.5g galactomannan, 0.2g fructooligosaccharide, 0.4g xylo-oligosaccharide, 0.5g sorbitol, 0.12g silicon dioxide and 0.12g magnesium stearate, stir at 35°C and 750r / min for 55min, then add 15g ethanol solution, and continue stirring for 60min; S4: Filter the mixture obtained in step S3, and concentrate it to 1 / 3 of the original solution at a vacuum degree of 0.05 MPa and a temperature of 62° C., thereby obtaining the intestinal-benefiting and lung-moistening Chinese medicine composition.

[0026] Comparative Example 1 The difference from Example 1 is that Ophiopogon japonicus and Polygonatum odoratum are not added in step S1, and the other steps remain unchanged.

[0027] Comparative Example 2 The difference from Example 1 is that Momordica grosvenori and Citrus aurantium are not added in step S1, and the other steps remain unchanged.

[0028] Comparative Example 3 The difference from Example 1 is that in step S2, ethanol is used as the solvent for direct immersion extraction, and ultrasonic countercurrent extraction is not used, and the other steps remain unchanged.

[0029] Comparative Example 4 The difference from Example 1 is that fructooligosaccharides and xylo-oligosaccharides are not added in step S3, and the other steps remain unchanged.

[0030] Comparative Example 5 The difference from Example 1 is that galactomannan and sorbitol are not added in step S3, and the other steps remain unchanged.

[0031] Each embodiment and comparative example was prepared into an ointment. 80 patients were selected, including 41 males and 39 females; aged 18-73 years old, with an average age of (45.82±9.33) years old; the course of disease was 2 months to 9 months, with an average course of disease of (5.9±1.3) months; divided into 8 groups, 10 people in each group for treatment, 15 ml once, 3 times a day, and taken for 10 days. Among them, for the judgment of the therapeutic effect, recovery: the symptoms basically disappeared after treatment, and the symptoms were reduced by ≥95; marked effect: the symptoms were significantly improved after treatment, 70%≤symptom reduction<95%; effective: the symptoms were improved after treatment, 30%≤symptom reduction<70%; ineffective: the symptoms were not significantly improved after treatment, or even aggravated, and the symptoms were reduced by <30%. Effective rate = (recovery + marked effect + effective) / total number of cases; the results are shown in the following table.

[0032] Table 1

[0033] It can be seen from the above performance test results that the Chinese medicine composition prepared in Examples 1-3 has a good effect of benefiting the intestine and moistening the lungs. In particular, Example 3 has an effective rate of 96%. However, since Comparative Examples 1-5 do not adopt the necessary technical solutions, their corresponding performance tests are significantly worse than those of the Examples. The above experimental results further prove the importance of the technical solutions defined in the present invention for its technical effects.

[0034] The above is a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. A Chinese medicine composition for benefiting intestines and moistening lungs, characterized in that: The invention comprises the following components in parts by weight: 10-15 parts of hemp seeds, 9-15 parts of momordica grosvenori, 9-12 parts of loquat leaves, 6-12 parts of ophiopogon japonicus, 6-10 parts of polygonatum odoratum, 6-8 parts of asparagus cochinchinensis, 4-8 parts of elderberry, 4-6 parts of dendrobium officinale, 4-6 parts of cistanche deserticola, 2-6 parts of liquorice, 2-5 parts of tangerine peel, 2-5 parts of astragalus, 0.2-0.5 parts of sugarcane polyphenols, 0.1-0.3 parts of VC and 0.001-0.002 parts of dihydroquercetin.

2. A Chinese medicine composition for benefiting intestines and moistening lungs according to claim 1, characterized in that: It also includes one or a mixture of 0.3-0.6 parts of galactomannan, 0.1-0.3 parts of oligofructose, 0.2-0.5 parts of oligoxylose, 0.3-0.6 parts of sorbitol, 0.05-0.15 parts of silicon dioxide and 0.08-0.16 parts of magnesium stearate.

3. A Chinese medicine composition for benefiting intestines and moistening lungs, characterized in that: The steps include: S1: Take 10-15 parts of hemp seeds, 9-15 parts of momordica grosvenori, 9-12 parts of loquat leaves, 6-12 parts of ophiopogon japonicus, 6-10 parts of polygonatum odoratum, 6-8 parts of asparagus cochinchinensis, 4-8 parts of elderberry, 4-6 parts of dendrobium officinale, 4-6 parts of cistanche deserticola, 2-6 parts of liquorice, 2-5 parts of tangerine peel, 2-5 parts of astragalus, 0.2-0.5 parts of sugarcane polyphenols, 0.1-0.3 parts of VC, and 0.001-0.002 parts of dihydroquercetin, and grind them to obtain a grinding mixture; S2: subjecting the crushed mixture in step S1 to ultrasonic countercurrent extraction; S3: separating the extract in step S2 into solid and liquid, taking the liquid phase and adding 0.3-0.6 parts of galactomannan, 0.1-0.3 parts of oligofructose, 0.2-0.5 parts of oligoxylose, 0.3-0.6 parts of sorbitol, 0.05-0.15 parts of silicon dioxide and 0.08-0.16 parts of magnesium stearate, stirring and reacting for 40-60 minutes; then adding 10-20 parts of ethanol solution, and continuing to stir and react for 55-75 minutes; S4: filtering and concentrating the mixture obtained in step S3 to obtain the intestinal-benefiting and lung-moistening Chinese medicine composition.

4. A Chinese medicine composition for benefiting intestines and moistening lungs according to claim 3, characterized in that: Step S1: After mixing the components of the Chinese medicine raw materials, send them to the ultrafine grinding equipment and grind them into a central particle size of 5-10 μm.

5. A Chinese medicine composition for benefiting intestines and moistening lungs according to claim 3, characterized in that: In the ultrasonic countercurrent extraction in step S2, a mixture of ammonia water and ethanol is used as the solvent, the solid-liquid ratio of the Chinese medicine raw material component and the solvent is 1g:12-20ml, and the extraction is carried out for 2-4h to obtain a crude extract; the crude extract is then concentrated to obtain a concentrated solution, which is centrifuged to obtain a Chinese medicine component extract.

6. A Chinese medicine composition for benefiting intestines and moistening lungs according to claim 5, characterized in that: The volume ratio of ammonia water to ethanol is 1-3:1; the vacuum concentration temperature is 35-45°C, the vacuum degree is 0.06-0.07MPa, and the time is 10-20min.

7. A Chinese medicine composition for benefiting intestines and moistening lungs according to claim 5, characterized in that: The speed of centrifugation is 800-1000 rps and the time is 5-10 min.

8. A Chinese medicine composition for benefiting intestines and moistening lungs according to claim 3, characterized in that: Step S3 is specifically as follows: separating the extract in step S2 into solid and liquid, taking the liquid phase and adding 0.3-0.6 parts of galactomannan, 0.1-0.3 parts of oligofructose, 0.2-0.5 parts of oligoxylose, 0.3-0.6 parts of sorbitol, 0.05-0.15 parts of silicon dioxide and 0.08-0.16 parts of magnesium stearate, stirring and reacting at a temperature of 30-40° C. at a rate of 600-800 r / min for 40-60 minutes; then adding 10-20 parts of ethanol solution, and continuing to stir and react for 55-75 minutes.

9. The Chinese medicine composition for benefiting intestines and moistening lungs according to claim 3, characterized in that: Step S4 is specifically as follows: the concentration temperature is 55-65° C., the vacuum degree is 0.04-0.06 MPa, and the concentration time is 25-35 min.

10. The Chinese medicine composition according to any one of claims 1 to 9 is applied to foods such as beverages, pastes, granules, tablets, solid beverages, etc.

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