Centrifuge tube capable of being operated in whole-course closed mode and operation method of centrifuge tube

Abstract

The invention discloses a whole-course closed operation centrifuge tube and an operation method thereof, the whole-course closed operation centrifuge tube comprises a sealing connection mechanism and a dustproof mechanism, the sealing connection mechanism comprises a sealing cover, a material port, an air port, a needleless joint, a puncture cap, a rubber plug assembly, a ventilation cap, an air filter membrane, a connection seat and a conduit. According to the whole-course closed operation centrifugal tube and the operation method thereof, when a blood sample needs to be injected into the tube body, the rubber plug assembly wraps the side wall of a syringe needle which is inserted into the rubber plug assembly in a penetrating manner and stores the blood sample, so that sealed injection is realized; on the other hand, when a sample needs to be sucked and extracted from the interior of the tube body, the rubber plug wraps the side wall of an empty syringe needle inserted into the rubber plug in a penetrating mode, then liquid obtained after centrifugation in the tube body can be sealed and extracted by pulling the syringe, and the ventilation cap plays a role in balancing the pressure intensity of air inside and outside the sealing cover; and meanwhile, the air filtering membrane filters and sterilizes the airflow flowing through the ventilation cap.

Description

Technical Field

[0001] The invention relates to the technical field of centrifuge tubes, in particular to a centrifuge tube with full-process closed operation and an operation method thereof. Background Art

[0002] A centrifuge tube is a tubular sample container, which can be provided with a sealing cover or a gland, and is usually used in conjunction with a centrifuge. After searching, it is found that the centrifuge tube in the prior art is typically a centrifuge tube such as the publication number CN113877650B, which belongs to the field of centrifugal technology, and includes a sealing component and a discharge component. The sealing component includes a centrifuge tube body, a sealing shell, a sealing rod, a reset spring, a mounting frame and a sealing rubber ring. The sealing shell is threadedly connected to the inner wall of the top of the centrifuge tube body, the sealing rod is threadedly embedded in the inner wall of the sealing shell, the reset spring is sleeved at the bottom end of the sealing rod, and the mounting frame is fixedly arranged at the bottom end of the sealing rod. Its main feature is that through the sealing component, the centrifuge tube body can be stably sealed to avoid the sample hitting the sealing shell during the centrifugation process, resulting in leakage of the contact gap, and then resulting in a decrease in centrifugal quality and loss of the sample. Secondly, combined with the discharge component, the internal part of the sample can be pressurized, and the layered samples of different heights can be quickly separated to ensure that the separation will not produce impurities. Mixing.

[0003] In summary, most of the existing centrifuge tubes are open when injecting blood samples, that is, the blood is exposed when the blood sample is injected into the centrifuge tube after the cover is opened, so that the blood sample has the hidden danger of being contaminated by the outside. In view of the above problems, the existing equipment needs to be improved. Summary of the invention

[0004] The object of the present invention is to provide a centrifuge tube with fully closed operation and an operation method thereof, so as to solve the problem proposed in the above background technology that most of the existing centrifuge tubes are open when injecting blood samples, that is, the blood is in an exposed state when the blood sample is injected into the centrifuge tube after the cover is opened, thereby causing the blood sample to be potentially contaminated by the outside.

[0005] To achieve the above object, the present invention provides the following technical solutions: a centrifuge tube with fully closed operation and an operation method thereof,

[0006] A centrifuge tube with fully closed operation, including a sealing connection mechanism and a dustproof mechanism,

[0007] The sealing connection mechanism includes a sealing cover, a material port, an air port, a needleless connector, a puncture cap, a plug assembly, a breathable cap, an air filter membrane, a connecting seat and a catheter, and the sealing cover is provided with a material port and an air port, the top of the material port is connected to the puncture cap, and the puncture cap is arranged on one side of the needleless connector, the other side of the needleless connector is provided with a breathable cap, and the breathable cap is connected to the top of the air port, and the top of the breathable cap is provided with an air filter membrane, the plug assembly includes a silicone plug and a rubber plug, and the silicone plug is arranged on the top of the needleless connector, and the rubber plug is arranged on the top of the puncture cap, the needleless connector is connected to the top of the connecting seat, and the connecting seat is arranged through the center of the sealing cover.

[0008] Preferably, the sealing connection mechanism further comprises a slot, and the slot is provided at the top outer edge of the sealing cover.

[0009] Preferably, the sealing cover is threadedly connected to the top of the tube body, and anti-slip edges are evenly arranged on the outer side wall of the sealing cover.

[0010] Preferably, the bottom of the connecting seat is connected to the top of the catheter, and the catheter is arranged inside the tube body.

[0011] Preferably, the needleless connector is snap-connected to the top of the connecting seat, and the connecting seat is snap-connected to the top of the catheter.

[0012] Preferably, the silicone plug is snap-fitted and connected inside the top of the needleless connector. The silicone plug is snap-fitted and connected inside the top of the needleless connector.

[0013] Preferably, the dustproof mechanism includes a dustproof cover, a fixing ring, a fixed baffle and an operating groove, and the interior of the dustproof cover is arranged with the fixed baffle, and an operating groove is opened on the fixed baffle, a fixing ring is arranged on the top of the dustproof cover, and the fixing ring is arranged on the outside of the operating groove, and the bottom of the dustproof cover is engaged with the outside of the slot.

[0014] Preferably, the dustproof mechanism further comprises a slide groove and a movable baffle, and the slide groove is provided on the inner wall of the fixed ring, and the movable baffle is slidably connected in the slide groove.

[0015] Preferably, the movable baffle includes a plate body, a hinge, a disc and a limiting magnet, and the inner side of the plate body is rotatably connected to the disc through the hinge, limiting magnets are correspondingly arranged on the side walls of the disc and the plate body, and the limiting magnets are magnetically connected.

[0016] Preferably, an operation method is applied to the above-mentioned centrifuge tube for full closed operation, comprising the following steps:

[0017] S1. Manually flip the disc to expose the top of the needleless connector, then insert the needle of the syringe containing the blood to be tested into the silicone plug at the top of the needleless connector, and discharge the blood into the catheter through the needleless connector, and then discharge it into the tube body through the catheter;

[0018] S2, flip the disc to reset, and then put the tube containing the blood sample into the centrifuge for centrifugal processing;

[0019] S3. After the centrifugal processing is completed, the movable baffle is manually pushed to move along the slide groove to expose the blocked puncture cap, and then a syringe is used to pass through the rubber stopper through the operating groove to suck and extract the liquid in the tube body.

[0020] Compared with the prior art, the invention has the following beneficial effects: the centrifuge tube with full closed operation and the operation method thereof,

[0021] (1) The present invention can effectively solve the problem that most of the existing centrifuge tubes are open when injecting blood samples, that is, the blood is exposed when injecting blood samples into the centrifuge tubes after opening the cap, so that the blood samples are at risk of being contaminated by the outside. When the blood sample needs to be injected into the tube body, the rubber plug assembly wraps the side wall of the syringe needle inserted into the tube body and storing the blood sample, thereby achieving sealed injection. On the other hand, when the sample needs to be extracted from the tube body, the rubber plug wraps the side wall of the empty syringe needle inserted into the tube body, and then the liquid after centrifugation in the tube body can be sealed and extracted by pulling the syringe. The air permeable cap plays a role in balancing the air pressure inside and outside the sealing cap. At the same time, the air filter membrane filters and sterilizes the airflow passing through the air permeable cap, thereby achieving aseptic and closed operation.

[0022] (2) The present invention can effectively solve the problem that silicone plugs and rubber plugs are easily contaminated by dust through the dustproof mechanism. The fixed baffle and the movable baffle cover and shield the silicone plug and the rubber plug when the device is not in use, thereby preventing them from being contaminated by dust. When it is necessary to inject a sample into the tube body, the staff can manually flip the disk to rotate it upward through the hinge to expose the top of the needleless connector, and then insert the needle of the syringe containing the blood to be tested into the silicone plug at the top of the needleless connector, and discharge the blood into the catheter through the needleless connector and into the tube body through the catheter. When it is necessary to extract the liquid in the tube body by suction, the movable baffle can be manually pushed along the slide groove to expose the blocked puncture cap, and then the syringe can be used to pass through the rubber plug through the operating groove to extract the liquid in the tube body. After extraction, the movable baffle can be reset by sliding it. The operation is simple and the dustproof effect is good. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1It is an isometric view of a centrifuge tube with full closed operation and its operation method of the present invention;

[0024] Figure 2 It is an exploded schematic diagram of a centrifuge tube with full closed operation and its operation method of the present invention;

[0025] Figure 3 The present invention is a cross-sectional structural schematic diagram of a centrifuge tube with fully closed operation and an operation method thereof;

[0026] Figure 4 An exploded view of a dust-proof mechanism of a centrifuge tube with full-process closed operation and an operation method thereof of the present invention;

[0027] Figure 5 This is a schematic diagram of the overall structure of a centrifuge tube with fully closed operation and its operation method when the dust-proof mechanism is not in use;

[0028] Figure 6 A centrifuge tube with fully closed operation and an operation method thereof Figure 5 A in the middle is an enlarged schematic diagram of the structure.

[0029] In the figure: 1. Sealing connection mechanism; 101. Sealing cover; 102. Material port; 103. Air port; 104. Needleless connector; 105. Puncture cap; 106. Plug assembly; 1061. Silicone plug; 1062. Rubber plug; 107. Breathable cap; 108. Air filter membrane; 109. Connecting seat; 1010. Catheter; 1011. Slot; 2. Tube body; 3. Dustproof mechanism; 301. Dustproof cover; 302. Fixed ring; 303. Fixed baffle; 304. Operating slot; 305. Slide slot; 306. Moving baffle; 3061. Plate body; 3062. Hinge; 3063. Disc; 3064. Limiting magnet. DETAILED DESCRIPTION

[0030] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0031] See also Figure 1-6 The present invention provides a technical solution: a centrifuge tube with full closed operation and an operation method thereof,

[0032] Embodiment 1

[0033] like Figure 1 , Figure 2 and Figure 3As shown, a centrifuge tube with full closed operation includes a sealing connection mechanism 1 and a dustproof mechanism 3, wherein the sealing connection mechanism 1 includes a sealing cover 101, a material port 102, an air port 103, a needleless connector 104, a puncture cap 105, a plug assembly 106, a breathable cap 107, an air filter membrane 108, a connecting seat 109 and a conduit 1010, and the sealing cover 101 is provided with a material port 102 and an air port 103, the top of the material port 102 is connected with a puncture cap 105, and the puncture cap 105 is arranged on one side of the needleless connector 104, A breathable cap 107 is provided on the other side of the needleless connector 104, and the breathable cap 107 is connected to the top of the air port 103, and an air filter membrane 108 is provided on the top of the breathable cap 107. The plug assembly 106 includes a silicone plug 1061 and a rubber plug 1062, and the silicone plug 1061 is provided on the top of the needleless connector 104, and the rubber plug 1062 is provided on the top of the puncture cap 105. The needleless connector 104 is connected to the top of the connecting seat 109, and the connecting seat 109 passes through the center of the circle provided on the sealing cover 101.

[0034] In a further embodiment, the sealing connection mechanism 1 further includes a slot 1011 , and the slot 1011 is opened at the top outer edge of the sealing cover 101 .

[0035] In a further embodiment, the sealing cover 101 is threadedly connected to the top of the tube body 2, and anti-skid edges are evenly arranged on the outer wall of the sealing cover 101, which play an anti-skid role, thereby making it easy for the staff to unscrew the sealing cover 101 from the top of the tube body 2.

[0036] In a further embodiment, the bottom of the connection seat 109 is connected to the top of the conduit 1010 , and the conduit 1010 is disposed inside the tube body 2 .

[0037] In a further embodiment, the needleless connector 104 is snap-connected to the top of the connection base 109 , and the connection base 109 is snap-connected to the top of the catheter 1010 .

[0038] In a further embodiment, the silicone plug 1061 is snap-fitted and connected inside the top of the needleless connector 104 . The silicone plug 1061 is snap-fitted and connected inside the top of the needleless connector 104 .

[0039] like Figure 4 , Figure 5 and Figure 6 As shown, in a further embodiment, the dustproof mechanism 3 includes a dustproof cover 301, a fixing ring 302, a fixing baffle 303 and an operating groove 304, and the interior of the dustproof cover 301 is arranged with the fixing baffle 303, and the fixing baffle 303 is provided with an operating groove 304, the top of the dustproof cover 301 is provided with a fixing ring 302, and the fixing ring 302 is arranged on the outside of the operating groove 304, and the bottom of the dustproof cover 301 is engaged with the outside of the slot 1011.

[0040] In a further embodiment, the dustproof mechanism 3 further includes a slide groove 305 and a movable baffle 306 , and the slide groove 305 is provided on the inner wall of the fixed ring 302 , and the movable baffle 306 is slidably connected in the slide groove 305 .

[0041] In a further embodiment, the movable baffle 306 includes a plate body 3061, a hinge 3062, a disc 3063 and a limiting magnet 3064, and the inner side of the plate body 3061 is rotatably connected to the disc 3063 through the hinge 3062, and limiting magnets 3064 are correspondingly arranged on the side walls of the disc 3063 and the plate body 3061, and the limiting magnets 3064 are magnetically connected. At the same time, the shape formed by the plate body 3061 and the disc 3063 is consistent with the shape of the operating groove 304 on the fixed baffle 303. At the same time, the external airflow enters the interior of the breathable cap 107 through the gap between the shape formed by the plate body 3061 and the disc 3063 and the operating groove 304, and enters the interior of the tube body 2 after being sterilized by the air filter membrane 108.

[0042] Specifically, when the inside of the device needs to be cleaned, the staff can manually pull the dust cover 301 off the top of the sealing cover 101, and then manually rotate the sealing cover 101 to remove it from the top of the tube body 2, and then clean the inside of the tube body 2. At the same time, the catheter 1010 that is engaged and connected is pulled out and separated from the bottom of the connecting seat 109, and then it can be classified and cleaned, thereby ensuring its sanitary quality and avoiding cross-contamination of subsequently stored samples. Then the staff manually pulls out the silicone plug 1061 from the inside of the needleless connector 104, and pulls out the rubber plug 1062 from the inner bottom of the puncture cap 105 for replacement, thereby ensuring the sealing of the device.

[0043] Embodiment 2

[0044] This embodiment is a further description of the above embodiment. It should be understood that this embodiment includes all the aforementioned technical features and is further described in detail.

[0045] In a further embodiment, an operation method is applied to the above-mentioned centrifuge tube for full closed operation, comprising the following steps:

[0046] S1. Manually flip the disc 3063 so that it rotates upward at the hinge 3062 to expose the top of the needleless connector 104. Then, insert the needle of the syringe containing the blood to be tested into the silicone plug 1061 at the top of the needleless connector 104, and discharge the blood into the catheter 1010 through the needleless connector 104, and then discharge it into the tube body 2 through the through hole at the bottom of the catheter 1010.

[0047] S2, manually flip the disc 3063 to reset, at this time, the disc 3063 is magnetically connected with the limiting magnet 3064 on the side of the disc 3063 and the limiting magnet 3064 on the inner side of the plate 3061 to achieve the limiting of the disc 3063, and then the tube 2 containing the blood sample is placed in the centrifuge for centrifugal processing;

[0048] S3. After the centrifugal processing is completed, the movable baffle 306 is manually pushed to move along the slide groove 305 and overlap with the fixed baffle 303 to expose the puncture cap 105 blocked below it, and then the needle on the syringe is used to penetrate through the operating groove 304 and the rubber plug 1062 to suck and extract the liquid in the tube body 2. At the same time, the air flow inside and outside the tube body 2 is circulated through the breathable cap 107, and the air filter membrane 108 filters and sterilizes the air flow entering the tube body 2 through the breathable cap 107.

[0049] Although the present invention has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments, or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A centrifuge tube for full-process closed operation, comprising a sealing connection mechanism (1) and a dust prevention mechanism (3), characterized in that: The sealing connection mechanism (1) comprises a sealing cover (101), a material port (102), an air port (103), a needleless connector (104), a puncture cap (105), a rubber plug assembly (106), a breathable cap (107), an air filter membrane (108), a connection seat (109) and a catheter (1010), wherein the sealing cover (101) is provided with a material port (102) and an air port (103), the top of the material port (102) is connected with a puncture cap (105), and the puncture cap (105) is arranged on one side of the needleless connector (104), and the other side of the needleless connector (104) is provided with a There is a breathable cap (107), and the breathable cap (107) is connected to the top of the air port (103), and an air filter membrane (108) is arranged on the top of the breathable cap (107), the plug assembly (106) includes a silicone plug (1061) and a rubber plug (1062), and the silicone plug (1061) is arranged on the top of the needleless connector (104), and the rubber plug (1062) is arranged on the top of the puncture cap (105), the needleless connector (104) is connected to the top of the connecting seat (109), and the connecting seat (109) is arranged through the center of the circle of the sealing cover (101).

2. A centrifuge tube for full closed operation according to claim 1, characterized in that: The sealing connection mechanism (1) further comprises a card slot (1011), and the card slot (1011) is provided at the top outer edge of the sealing cover (101).

3. A centrifuge tube for full closed operation according to claim 1, characterized in that: The sealing cover (101) is threadedly connected to the top of the tube body (2), and anti-slip edges are evenly arranged on the outer side wall of the sealing cover (101).

4. A centrifuge tube for full closed operation according to claim 1, characterized in that: The bottom of the connection seat (109) is connected to the top of the conduit (1010), and the conduit (1010) is arranged inside the tube body (2).

5. A centrifuge tube for full-process closed operation according to claim 1, characterized in that: The needleless connector (104) is snap-connected with the top of the connecting seat (109), and the connecting seat (109) is snap-connected with the top of the catheter (1010).

6. A centrifuge tube for full-process closed operation according to claim 1, characterized in that: The silicone rubber plug (1061) is snap-fitted and connected inside the top of the needleless connector (104). The silicone rubber plug (1061) is snap-fitted and connected inside the top of the needleless connector (104).

7. A centrifuge tube for full-process closed operation according to claim 1, characterized in that: The dustproof mechanism (3) comprises a dustproof cover (301), a fixing ring (302), a fixing baffle (303) and an operating slot (304), and the dustproof cover (301) is provided with a fixing baffle (303) inside, and the fixing baffle (303) is provided with an operating slot (304), the top of the dustproof cover (301) is provided with a fixing ring (302), and the fixing ring (302) is provided on the outside of the operating slot (304), and the bottom of the dustproof cover (301) is engaged with the outside of the slot (1011).

8. The centrifuge tube for full closed operation according to claim 1, characterized in that: The dustproof mechanism (3) further comprises a slide groove (305) and a movable baffle (306), wherein the slide groove (305) is provided on the inner wall of the fixed ring (302), and the movable baffle (306) is slidably connected in the slide groove (305).

9. A centrifuge tube for full-process closed operation according to claim 8, characterized in that: The movable baffle (306) comprises a plate body (3061), a hinge (3062), a disc (3063) and a limiting magnet (3064), and the inner side of the plate body (3061) is rotatably connected to the disc (3063) via the hinge (3062), and limiting magnets (3064) are correspondingly arranged on the side walls of the disc (3063) and the plate body (3061), and the limiting magnets (3064) are magnetically connected to each other.

10. An operating method, applied to the centrifuge tube for full closed operation according to any one of claims 1 to 9, characterized in that: The following steps are involved: S1. Manually flip the disc (3063) to expose the top of the needleless connector (104), then insert the needle of the syringe containing the blood to be tested into the silicone plug (1061) at the top of the needleless connector (104), and discharge the blood into the inside of the catheter (1010) through the needleless connector (104), and then discharge it into the inside of the tube body (2) through the catheter (1010); S2, the turning disc (3063) is reset, and then the tube (2) containing the blood sample is placed inside the centrifuge for centrifugal processing; S3. After the centrifugal processing is completed, the movable baffle (306) is manually pushed to move along the slide groove (305) to expose the blocked puncture cap (105), and then a syringe is used to pass through the operating groove (304) and the rubber stopper (1062) to suck and extract the liquid in the tube body (2).

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