Method and device for preparing dexamethasone palmitate

By designing a dexamethasone palmitate preparation device that includes clamping, shaking and vibrating components, the problem of uneven mixing of dexamethasone palmitate is solved, and a more efficient and stable mixing effect is achieved.

CN119632837APending Publication Date: 2025-03-18XIAN GUOKANG PHARM CO LTD
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Patent Information

Application Number
CN202510098155.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-21
Publication Date
2025-03-18

AI Technical Summary

Technical Problem

Dexamethasone palmitate is mixed unevenly before injection, resulting in unstable therapeutic effect.

Method used

A dexamethasone palmitate preparation device is designed, including a housing, a clamping member, a shaking member and a vibrating member. The rotor is driven by the motor to rotate, and the piston rod pushes the disc up and down, driving the mixing bottle to move up and down simultaneously, combining the squeezing effect of the rubber ring and the elastic rod to ensure even mixing.

Benefits of technology

It effectively avoids the problem of uneven mixing, improves the mixing efficiency and stability of dexamethasone palmitate, and reduces the risk of manual shaking of medical staff.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of dexamethasone palmitate preparation, and discloses a dexamethasone palmitate preparation method and a dexamethasone palmitate preparation device, the dexamethasone palmitate preparation device comprises a shell, the shell is internally provided with a clamping part; the clamping part comprises a fixing plate, the surface of the fixing plate is fixedly connected with the inner wall of the shell, the top of the fixing plate is fixedly connected with a sliding hole frame, the surface of the sliding hole frame is fixedly connected with a fixing ring, the top of the fixing ring is fixedly connected with an elastic rod, the top of the elastic rod is rotationally connected with a positioning ring, and the bottom of the positioning ring is fixedly connected with a rubber ring. According to the dexamethasone palmitate injection device, after dexamethasone palmitate is injected into a mixing bottle, a positioning ring is twisted to rotate to the outer end of a sliding hole frame, the mixing bottle is placed in the sliding hole frame to make contact with the top of a disc, an elastic rod is pulled, and the positioning ring is pushed to rotate to the position above the mixing bottle; the rubber ring is in contact with the surface of the mixing bottle by utilizing the elasticity of the elastic rod and extrudes the mixing bottle, so that the stability of the mixing bottle during vertical shaking is improved.
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Description

Technical Field

[0001] The invention relates to the technical field of dexamethasone palmitic acid preparation, in particular to a dexamethasone palmitic acid preparation method and device. Background Art

[0002] Dexamethasone palmitate is a synthetic drug, and its common dosage form is injection. This drug belongs to the glucocorticoid class of drugs, and has anti-inflammatory, anti-allergic and immunosuppressive effects. It is mainly used clinically to treat respiratory diseases such as bronchial asthma, asthmatic bronchitis, obstructive pulmonary emphysema, cor pulmonale, and can also be used to treat dermatological diseases such as eczema, neurodermatitis, contact dermatitis, psoriasis (psoriasis), and senile pruritus.

[0003] Dexamethasone palmitate needs to be mixed before injection. Generally, medical staff inject dexamethasone palmitate into the mixing bottle and then shake it manually to mix it. Dexamethasone palmitate is prone to uneven mixing after simple shaking by medical staff. Summary of the invention

[0004] The object of the present invention is to provide a method and device for preparing dexamethasone palmitic acid to solve the problems raised in the above background technology.

[0005] In order to solve the above technical problems, the present invention is achieved through the following technical solutions:

[0006] The present invention is a method and device for preparing dexamethasone palmitic acid, comprising a housing, wherein a clamping component is arranged inside the housing;

[0007] The top of the fixing plate is fixedly connected to the inner wall of the shell, and the top of the fixing plate is fixedly connected to a sliding hole frame, the surface of the sliding hole frame is fixedly connected to a fixing ring, the top of the fixing ring is fixedly connected to an elastic rod, the top of the elastic rod is rotatably connected to a positioning ring, and the bottom of the positioning ring is fixedly connected to a rubber ring, the inner wall of the sliding hole frame is fixedly connected to the positioning frame, the inner wall of the sliding hole frame is slidably connected to a disc, the inner wall of the disc is fixedly connected to a mounting plate, the top of the mounting plate is fixedly connected to a bent plate, one end of the bent plate away from the mounting plate is hinged with a pressure plate, one end of the pressure plate away from the bent plate is fixedly connected to a rubber rod, the pressure plate and the bent plate are fixedly connected to the spring sheet, the pressure plate and the mounting plate are fixedly connected to the elastic sheet, a shaking component is arranged below the disc, and a vibration component is arranged on the surface of the shaking component.

[0008] Furthermore, the positioning ring is located above the sliding hole frame, the inner wall of the disc is slidably connected to the surface of the positioning frame, there are four bent plates, the four bent plates are arranged in a circle with the disc as the center, and the rubber rod is located above the disc.

[0009] Furthermore, the shaking component includes an articulated frame, the top of the articulated frame is fixedly connected to the bottom of the disc, the inner wall of the articulated frame is rotatably connected to a piston rod, the lower surface of the piston rod is rotatably connected to a turntable, the inner wall of the outer shell is fixedly connected to a motor, the inner wall of the outer shell is rotatably connected to a stabilizing rod, and the surface of the turntable is provided with a groove.

[0010] Furthermore, there are two turntables, which are symmetrically arranged with the piston rod as the center, the stabilizing rod is located at the end of the shell away from the motor, and the output end of the motor and the end of the stabilizing rod close to each other are fixedly connected to the surfaces of the two turntables respectively.

[0011] Furthermore, the bottom of the piston rod extends to below the fixed plate, and a plurality of grooves are arranged on the surface of the turntable. The plurality of grooves are arranged in two groups, and the two groups of grooves are symmetrically arranged with the turntable as the center.

[0012] Furthermore, the vibration component includes a limit frame, the inner wall of the limit frame is rotatably connected to the surface of the stabilizing rod, the end of the limit frame is fixedly connected to a rectangular frame, the end of the rectangular frame is fixedly connected to a semicircular plate, the inner wall of the semicircular plate is fixedly connected to a circular arc spring plate, the surface of the circular arc spring plate is fixedly connected to a cylindrical contact rod, the surface of the limit frame is fixedly connected to a vertical plate, and the bottom of the vertical plate is fixedly connected to the bottom of the inner wall of the outer shell.

[0013] Furthermore, the number of the rectangular frames is two, and the two rectangular frames are symmetrically arranged with the limiting frame as the center, and the surface of the cylindrical contact rod is in contact with the inner wall of the groove.

[0014] Furthermore, the limit frame is symmetrically arranged with the stabilizing rod as the center, the number of the semicircular plates is four, the four semicircular plates are arranged in two groups, and the number of each group is two, and the turntable is located at one end where the two semicircular plates are close to each other.

[0015] Furthermore, a method for preparing a dexamethasone palmitic acid lipid comprises the following steps:

[0016] S1: After injecting dexamethasone palmitate into the mixing bottle, twist the positioning ring to rotate to the outer end of the sliding hole frame, place the mixing bottle inside the sliding hole frame so that it contacts the top of the disc, pull the elastic rod and push the positioning ring to rotate above the mixing bottle, and the rubber ring contacts the surface of the mixing bottle using the elasticity of the elastic rod and squeezes it;

[0017] S2: When the bottom of the mixing bottle contacts the top of the disc, it squeezes the pressure plate to move toward the surface of the curved plate. The rubber rod at the bottom of the pressure plate uses the elasticity of the spring and the elastic sheet to squeeze the mixing bottle, thereby improving the stability of the mixing bottle when mixing dexamethasone palmitate, so that the mixing bottle can move up and down synchronously with the disc;

[0018] S3: When the turntable rotates, it pushes the piston rod to move up and down. When the piston rod moves up and down, it pushes the disc to shake up and down inside the sliding hole rack through the hinged frame. When the disc shakes upward, it drives the mixing bottle to move up and down to mix the dexamethasone palmitic acid inside it;

[0019] S4: When the turntable rotates, the groove on the surface will contact the surface of the cylindrical contact rod, and separate from the cylindrical contact rod through rotation and squeeze the arc spring plate to produce deformation. The reciprocating contact and separation of the groove with the cylindrical contact rod will produce vibration.

[0020] The present invention has the following beneficial effects:

[0021] After dexamethasone palmitate is injected into the mixing bottle, the positioning ring is twisted and rotated to the outer end of the sliding hole frame, the mixing bottle is placed in the sliding hole frame to contact the top of the disc, and the elastic rod is pulled and the positioning ring is pushed to rotate above the mixing bottle. The rubber ring contacts and squeezes the surface of the mixing bottle by the elasticity of the elastic rod, thereby improving the stability of the mixing bottle when shaking up and down. When the bottom of the mixing bottle contacts the top of the disc, the pressure plate is squeezed to move toward the surface of the bent plate. The rubber rod at the bottom of the pressure plate squeezes the mixing bottle by the elasticity of the spring sheet and the elastic sheet, thereby improving the stability of the mixing bottle when mixing dexamethasone palmitate, so that the mixing bottle can move up and down synchronously with the disc, thereby preventing the disc from separating from the mixing bottle when moving, causing the disc to collide with the dexamethasone palmitate and cause the mixing bottle to break.

[0022] The present invention starts a motor to drive the turntable to rotate inside an outer shell. When the turntable rotates, the piston rod pushes the stabilizing rod to rotate on the inner wall of the outer shell. The stabilizing rod and the motor are used to limit the turntable, thereby improving the stability of the turntable when it rotates. When the turntable rotates, the piston rod is pushed to move up and down. When the piston rod moves up and down, the disc is pushed to shake up and down inside the sliding hole frame through the hinge frame. When the disc shakes upward, it drives the mixing bottle to move up and down to mix the dexamethasone palmitate inside the mixing bottle, thereby improving the convenience of the dexamethasone palmitate when being mixed and prepared, and avoiding the situation that medical staff manually mix the dexamethasone palmitate and cause uneven mixing.

[0023] When the turntable of the present invention rotates, the grooves on the surface will contact the surface of the cylindrical contact rod, and will be separated from the cylindrical contact rod by rotation and squeeze the arc spring plate to produce deformation. The reciprocating contact and separation of the grooves with the cylindrical contact rod will generate vibration, and the vibration will be transmitted to the disk through the piston rod, so that the vibration can oscillate the dexamethasone palmitate in the mixing bottle, thereby further improving the mixing efficiency of the dexamethasone palmitate.

[0024] Of course, any product implementing the present invention does not necessarily need to achieve all of the advantages described above at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for describing the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative work.

[0026] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0027] Figure 2 This is a schematic diagram of the cross-sectional structure of the housing of the present invention;

[0028] Figure 3 This is a schematic diagram of the internal structure of the housing of the present invention;

[0029] Figure 4 It is a schematic diagram of the overall structure of the clamping component of the present invention;

[0030] Figure 5 For the present invention Figure 4 A magnified schematic diagram of part A in FIG.

[0031] Figure 6 It is a schematic diagram of the overall structure of the shaking component of the present invention;

[0032] Figure 7 Another structural schematic diagram of the shaking component of the present invention;

[0033] Figure 8 It is a schematic diagram of the overall structure of the vibration component of the present invention;

[0034] Fig. 9 It is a schematic diagram of the process structure of the present invention.

[0035] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0036] In the figure: 1. shell; 2. clamping part; 3. shaking part; 4. vibration part; 10. fixing plate; 11. sliding hole frame; 12. disc; 13. elastic rod; 14. positioning ring; 15. rubber ring; 16. positioning frame; 17. fixing ring; 18. pressure plate; 19. spring piece; 20. bending plate; 21. mounting plate; 22. elastic piece; 23. rubber rod; 40. piston rod; 41. turntable; 42. stabilizing rod; 43. groove; 44. articulated frame; 45. motor; 50. semicircular plate; 51. cylindrical contact rod; 52. rectangular frame; 53. vertical plate; 54. arc spring plate; 55. limit frame. DETAILED DESCRIPTION

[0037] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0038] See also Figure 1-Figure 9 As shown, the present invention is a method and device for preparing dexamethasone palmitic acid, comprising a housing 1, wherein a clamping component 2 is disposed inside the housing 1;

[0039] The clamping component 2 includes a fixing plate 10, the surface of the fixing plate 10 is fixedly connected to the inner wall of the housing 1, the top of the fixing plate 10 is fixedly connected to a sliding hole frame 11, the surface of the sliding hole frame 11 is fixedly connected to a fixing ring 17, the top of the fixing ring 17 is fixedly connected to an elastic rod 13, the top of the elastic rod 13 is rotatably connected to a positioning ring 14, the bottom of the positioning ring 14 is fixedly connected to a rubber ring 15, the inner wall of the sliding hole frame 11 is fixedly connected to a positioning frame 16, and the inner wall of the sliding hole frame 11 is slidably connected to a disc 1 2. The inner wall of the disk 12 is fixedly connected with a mounting plate 21, the top of the mounting plate 21 is fixedly connected with a bent plate 20, the end of the bent plate 20 away from the mounting plate 21 is hinged with a pressure plate 18, the end of the pressure plate 18 away from the bent plate 20 is fixedly connected with a rubber rod 23, the pressure plate 18 and the bent plate 20 are fixedly connected by a spring sheet 19, the pressure plate 18 and the mounting plate 21 are fixedly connected by an elastic sheet 22, a shaking component 3 is arranged below the disk 12, and a vibration component 4 is arranged on the surface of the shaking component 3.

[0040] The positioning ring 14 is located above the slide hole frame 11, and the inner wall of the disc 12 is slidably connected to the surface of the positioning frame 16. The number of the bent plates 20 is four. After injecting dexamethasone palmitate into the interior of the mixing bottle, the positioning ring 14 is twisted and rotated to the outer end of the slide hole frame 11, and the mixing bottle is placed inside the slide hole frame 11 to contact the top of the disc 12. After pulling the elastic rod 13 and pushing the positioning ring 14 to rotate to the top of the mixing bottle, the rubber ring 15 uses the elasticity of the elastic rod 13 to contact and squeeze the surface of the mixing bottle, thereby improving the stability of the mixing bottle when it is shaken up and down. When the bottom of the mixing bottle contacts the top of the disc 12, the pressure plate 18 will be squeezed to move toward the surface of the bent plate 20. The rubber rod 23 at the bottom of the pressure plate 18 will use the elasticity of the spring sheet 19 and the elastic sheet 22 to squeeze the mixing bottle, thereby improving the stability of the mixing bottle when mixing dexamethasone palmitate, so that the mixing bottle can move up and down synchronously with the disc 12, avoiding the disc 12 from separating from the mixing bottle when moving, causing the disc 12 to collide with the dexamethasone palmitate and cause the mixing bottle to break. The four bent plates 20 are arranged around the disc 12 as the center circle, and the rubber rod 23 is located above the disc 12.

[0041] The shaking component 3 includes an articulated frame 44, the top of the articulated frame 44 is fixedly connected to the bottom of the disc 12, the inner wall of the articulated frame 44 is rotatably connected to a piston rod 40, the lower surface of the piston rod 40 is rotatably connected to a turntable 41, the inner wall of the outer shell 1 is fixedly connected to a motor 45, the inner wall of the outer shell 1 is rotatably connected to a stabilizing rod 42, and a groove 43 is provided on the surface of the turntable 41.

[0042] There are two turntables 41, which are symmetrically arranged with the piston rod 40 as the center. The stabilizing rod 42 is located at the end of the housing 1 away from the motor 45. The present invention starts the motor 45 to drive the turntable 41 to rotate inside the housing 1. When the turntable 41 rotates, the piston rod 40 pushes the stabilizing rod 42 to rotate on the inner wall of the housing 1. The stabilizing rod 42 and the motor 45 are used to limit the turntable 41, thereby improving the stability of the turntable 41 when rotating. When the turntable 41 rotates, it pushes the piston rod 40 to move up and down. When the piston rod 40 moves up and down, it will push the disc 12 to swing up and down inside the slide hole frame 11 through the hinge frame 44. When the disc 12 swings upward, it will drive the mixing bottle to move up and down to mix the dexamethasone palmitic acid inside it, thereby improving the convenience of dexamethasone palmitic acid during mixing and preparation, and avoiding the situation where medical staff manually mix the dexamethasone palmitic acid and cause uneven mixing. The output end of the motor 45 and the end of the stabilizing rod 42 that is close to each other are fixedly connected to the surfaces of the two turntables 41 respectively.

[0043] The bottom of the piston rod 40 extends to the bottom of the fixed plate 10 . The surface of the rotating disk 41 is provided with a plurality of grooves 43 . The plurality of grooves 43 are arranged in two groups. The two groups of grooves 43 are symmetrically arranged with the rotating disk 41 as the center.

[0044] The vibration component 4 includes a limit frame 55, the inner wall of the limit frame 55 is rotatably connected to the surface of the stabilizing rod 42, the end of the limit frame 55 is fixedly connected to a rectangular frame 52, the end of the rectangular frame 52 is fixedly connected to a semicircular plate 50, the inner wall of the semicircular plate 50 is fixedly connected to a circular arc spring plate 54, the surface of the circular arc spring plate 54 is fixedly connected to a cylindrical contact rod 51, the surface of the limit frame 55 is fixedly connected to a vertical plate 53, and the bottom of the vertical plate 53 is fixedly connected to the bottom of the inner wall of the outer shell 1.

[0045] There are two rectangular frames 52 , which are symmetrically arranged with the limiting frame 55 as the center. The surface of the cylindrical contact rod 51 contacts the inner wall of the groove 43 .

[0046] The limit frame 55 is symmetrically arranged with the stabilizing rod 42 as the center. When the turntable 41 of the present invention rotates, the groove 43 on the surface will contact the surface of the cylindrical contact rod 51, and separate from the cylindrical contact rod 51 by rotation and squeeze the arc spring plate 54 to produce deformation. The reciprocating contact and separation of the groove 43 with the cylindrical contact rod 51 will produce vibration, and the vibration will be transmitted to the disk 12 through the piston rod 40, so that the vibration can vibrate the dexamethasone palmitate in the mixing bottle, further improving the mixing efficiency of the dexamethasone palmitate. There are four semicircular plates 50, and the four semicircular plates 50 are arranged in two groups, and the number of each group is two. The turntable 41 is located at one end where the two semicircular plates 50 are close to each other.

[0047] A method for preparing a dexamethasone palmitic acid lipid comprises the following steps:

[0048] S1: After injecting dexamethasone palmitate into the mixing bottle, twist the positioning ring 14 to rotate to the outer end of the slide hole frame 11, place the mixing bottle inside the slide hole frame 11 to contact the top of the disc 12, pull the elastic rod 13 and push the positioning ring 14 to rotate to the top of the mixing bottle, and the rubber ring 15 uses the elasticity of the elastic rod 13 to contact the surface of the mixing bottle and squeeze it;

[0049] S2: After the bottom of the mixing bottle contacts the top of the disc 12, it squeezes the pressure plate 18 to move toward the surface of the curved plate 20. The rubber rod 23 at the bottom of the pressure plate 18 uses the elasticity of the spring sheet 19 and the elastic sheet 22 to squeeze the mixing bottle, thereby improving the stability of the mixing bottle when mixing dexamethasone palmitate, so that the mixing bottle can move up and down synchronously with the disc 12.

[0050] S3: When the rotating disk 41 rotates, it pushes the piston rod 40 to move up and down. When the piston rod 40 moves up and down, it pushes the disc 12 to shake up and down inside the sliding hole frame 11 through the hinge frame 44. When the disc 12 shakes upward, it drives the mixing bottle to move up and down to mix the dexamethasone palmitic acid resin inside it;

[0051] S4: When the turntable 41 rotates, the groove 43 on the surface will contact the surface of the cylindrical contact rod 51, and separate from the cylindrical contact rod 51 through rotation and squeeze the arc spring plate 54 to produce deformation. The reciprocating contact and separation of the groove 43 with the cylindrical contact rod 51 will generate vibration.

[0052] When in use, after injecting dexamethasone palmitate into the interior of the mixing bottle, twist the positioning ring 14 to rotate to the outer end of the slide hole frame 11, place the mixing bottle in the interior of the slide hole frame 11 to contact the top of the disc 12, pull the elastic rod 13 and push the positioning ring 14 to rotate to the top of the mixing bottle, the rubber ring 15 utilizes the elasticity of the elastic rod 13 to contact and squeeze the surface of the mixing bottle, thereby improving the stability of the mixing bottle when it is shaken up and down, and when the bottom of the mixing bottle contacts the top of the disc 12, it squeezes the pressure plate 18 to the bending plate 20 When the surface of the pressure plate 18 moves, the rubber rod 23 at the bottom of the pressure plate 18 will use the elasticity of the spring sheet 19 and the elastic sheet 22 to squeeze the mixing bottle, thereby improving the stability of the mixing bottle when mixing dexamethasone palmitate, so that the mixing bottle can move up and down synchronously with the disc 12, thereby preventing the disc 12 from separating from the mixing bottle when moving, causing the disc 12 to hit the dexamethasone palmitate and cause the mixing bottle to break, and starting the motor 45 to drive the turntable 41 to rotate inside the housing 1. When the turntable 41 rotates, it pushes the stabilizing rod 42 in the housing 1 through the piston rod 40. The inner wall of the rotating disk 41 is rotated, and the stabilizing rod 42 and the motor 45 are used to limit the rotating disk 41, so as to improve the stability of the rotating disk 41 during rotation. When the rotating disk 41 rotates, the piston rod 40 is pushed to move up and down. When the piston rod 40 moves up and down, it pushes the disc 12 to shake up and down inside the sliding hole rack 11 through the hinge frame 44. When the disc 12 shakes upward, it drives the mixing bottle to move up and down to mix the dexamethasone palmitic acid inside it, thereby improving the convenience of the mixing preparation of the dexamethasone palmitic acid and avoiding the medical staff Manual mixing of dexamethasone palmitate may result in uneven mixing. When the turntable 41 rotates, the groove 43 on the surface will contact the surface of the cylindrical contact rod 51, and the groove 43 will separate from the cylindrical contact rod 51 through rotation and squeeze the arc spring plate 54 to deform. The reciprocating contact and separation of the groove 43 with the cylindrical contact rod 51 will generate vibration, which will be transmitted to the disk 12 through the piston rod 40, so that the vibration can oscillate the dexamethasone palmitate in the mixing bottle, further improving the mixing efficiency of the dexamethasone palmitate.

[0053] The preferred embodiments of the present invention disclosed above are only used to help illustrate the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the invention to the specific implementation methods described. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can understand and use the present invention well. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A dexamethasone palmitic acid preparation device, comprising a housing (1), characterized in that: A clamping component (2) is provided inside the housing (1); The clamping component (2) comprises a fixing plate (10), the surface of the fixing plate (10) is fixedly connected to the inner wall of the housing (1), the top of the fixing plate (10) is fixedly connected to a sliding hole frame (11), the surface of the sliding hole frame (11) is fixedly connected to a fixing ring (17), the top of the fixing ring (17) is fixedly connected to an elastic rod (13), the top of the elastic rod (13) is rotatably connected to a positioning ring (14), the bottom of the positioning ring (14) is fixedly connected to a rubber ring (15), the inner wall of the sliding hole frame (11) is fixedly connected to a positioning frame (16), and the inner wall of the sliding hole frame (11) is slidably connected to a disc (12). The inner wall of the disk (12) is fixedly connected to a mounting plate (21), the top of the mounting plate (21) is fixedly connected to a bent plate (20), the end of the bent plate (20) away from the mounting plate (21) is hinged to a pressure plate (18), the end of the pressure plate (18) away from the bent plate (20) is fixedly connected to a rubber rod (23), the pressure plate (18) and the bent plate (20) are fixedly connected via a spring sheet (19), the pressure plate (18) and the mounting plate (21) are fixedly connected via an elastic sheet (22), a shaking component (3) is arranged below the disk (12), and a vibrating component (4) is arranged on the surface of the shaking component (3).

2. A dexamethasone palmitic acid preparation device according to claim 1, characterized in that: The positioning ring (14) is located above the sliding hole frame (11), the inner wall of the disc (12) is slidably connected to the surface of the positioning frame (16), the number of the bent plates (20) is four, and the four bent plates (20) are arranged with the disc (12) as the center circumference, and the rubber rod (23) is located above the disc (12).

3. A dexamethasone palmitic acid preparation device according to claim 2, characterized in that: The shaking component (3) includes an articulated frame (44), the top of the articulated frame (44) is fixedly connected to the bottom of the disc (12), the inner wall of the articulated frame (44) is rotatably connected to a piston rod (40), the lower surface of the piston rod (40) is rotatably connected to a turntable (41), the inner wall of the outer shell (1) is fixedly connected to a motor (45), the inner wall of the outer shell (1) is rotatably connected to a stabilizing rod (42), and a groove (43) is provided on the surface of the turntable (41).

4. A dexamethasone palmitic acid preparation device according to claim 3, characterized in that: There are two rotating disks (41), which are symmetrically arranged with the piston rod (40) as the center. The stabilizing rod (42) is located at the end of the housing (1) away from the motor (45), and the output end of the motor (45) and the end of the stabilizing rod (42) close to each other are fixedly connected to the surfaces of the two rotating disks (41) respectively.

5. A dexamethasone palmitic acid preparation device according to claim 4, characterized in that: The bottom of the piston rod (40) extends to below the fixed plate (10), and a plurality of grooves (43) are arranged on the surface of the rotating disk (41). The plurality of grooves (43) are arranged in two groups, and the two groups of grooves (43) are symmetrically arranged with the rotating disk (41) as the center.

6. A dexamethasone palmitic acid preparation device according to claim 5, characterized in that: The vibration component (4) comprises a limit frame (55), the inner wall of the limit frame (55) is rotatably connected to the surface of the stabilizing rod (42), the end of the limit frame (55) is fixedly connected to a rectangular frame (52), the end of the rectangular frame (52) is fixedly connected to a semicircular plate (50), the inner wall of the semicircular plate (50) is fixedly connected to a circular arc spring plate (54), the surface of the circular arc spring plate (54) is fixedly connected to a cylindrical contact rod (51), the surface of the limit frame (55) is fixedly connected to a vertical plate (53), and the bottom of the vertical plate (53) is fixedly connected to the bottom of the inner wall of the outer shell (1).

7. A dexamethasone palmitic acid preparation device according to claim 6, characterized in that: There are two rectangular frames (52), which are symmetrically arranged with the limiting frame (55) as the center, and the surface of the cylindrical contact rod (51) contacts the inner wall of the groove (43).

8. A dexamethasone palmitic acid preparation device according to claim 7, characterized in that: The limiting frame (55) is symmetrically arranged with the stabilizing rod (42) as the center, the number of the semicircular plates (50) is four, the four semicircular plates (50) are arranged in two groups, and the number of each group is two, and the rotating disk (41) is located at one end where the two semicircular plates (50) are close to each other.

9. The method for preparing dexamethasone palmitic acid according to claim 8, characterized in that: The following steps are involved: S1: After injecting dexamethasone palmitate into the interior of the mixing bottle, twist the positioning ring (14) to rotate to the outer end of the sliding hole frame (11), place the mixing bottle inside the sliding hole frame (11) so that it contacts the top of the disc (12), pull the elastic rod (13) and push the positioning ring (14) to rotate to the top of the mixing bottle, and then the rubber ring (15) contacts the surface of the mixing bottle by utilizing the elasticity of the elastic rod (13) and squeezes it; S2: When the bottom of the mixing bottle contacts the top of the disc (12), the pressure plate (18) is pressed to move toward the surface of the curved plate (20). The rubber rod (23) at the bottom of the pressure plate (18) uses the elasticity of the spring sheet (19) and the elastic sheet (22) to press the mixing bottle, thereby improving the stability of the mixing bottle when mixing dexamethasone palmitate, so that the mixing bottle can move up and down synchronously with the disc (12); S3: When the rotating disk (41) rotates, it pushes the piston rod (40) to move up and down. When the piston rod (40) moves up and down, it pushes the disc (12) to shake up and down inside the sliding hole frame (11) through the hinge frame (44). When the disc (12) shakes upward, it drives the mixing bottle to move up and down to mix the dexamethasone palmitate inside the mixing bottle; S4: When the rotating disk (41) rotates, the groove (43) on the surface will contact the surface of the cylindrical contact rod (51), and will separate from the cylindrical contact rod (51) through rotation and squeeze the arc spring plate (54) to produce deformation. The groove (43) will reciprocately contact and separate with the cylindrical contact rod (51) to generate vibration.