External traditional Chinese medicine composition for relieving eye dryness and eyestrain as well as preparation method and application of external traditional Chinese medicine composition

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an external traditional Chinese medicine composition for relieving eye dryness and eyestrain as well as a preparation method and application thereof. The external traditional Chinese medicine composition is prepared from calcined magnetite, nacre mother of pearl, feather cockscomb seed, butterflybush flower, tribulus terrestris, raw cassia seed, mint and borneol. The external traditional Chinese medicine composition has the effects of dredging orifices, dissipating stagnated fire, removing nebula, improving eyesight, calming the liver, suppressing yang, clearing head and eyes, soothing the nerves and stabilizing the mind. The external traditional Chinese medicine composition disclosed by the invention is simple in formula and reasonable in compatibility, effective components can be more concentrated on eyes to take effect through an external dosage form, and the external traditional Chinese medicine composition is remarkable in curative effect and free from any toxic and side effects. The external traditional Chinese medicine composition is particularly suitable for daily nursing of people with dry eyes, eye acerbity, eyestrain, eye pain, eye hyperemia and blurred vision caused by long-term use of electronic products, learning and staying up late, and has auxiliary effects on controlling eye degree growth and relieving swelling and headache in head, insomnia, amnesia, dysphoria, irritability and inattention.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an external Chinese medicine composition for relieving dry eyes and eye fatigue, and a preparation method and use thereof. Background Art

[0002] In the digital age, our eyes face unprecedented challenges. Staring at electronic screens such as computers and mobile phones for a long time can easily lead to dry eyes and fatigue. Dry eyes, medically known as dry eyes, are caused by insufficient secretion of tears or too fast evaporation, resulting in insufficient moisture on the surface of the eyes, causing discomfort. Symptoms include stinging, burning, foreign body sensation in the eyes, and blurred vision. Eye fatigue, or asthenopia, is caused by excessive tension and fatigue of the eye muscles due to long-term focus on close objects. This may be accompanied by headaches, eye pain, sensitivity to light, and difficulty focusing. Myopia is a common vision problem that manifests as distant objects appear blurry, while nearby objects are relatively clear. This is because the eyeball is too long or the corneal curvature is too large, causing light to focus in front of the retina instead of directly on the retina. With the increase in work and study pressure, the proportion of teenagers suffering from myopia and astigmatism has increased significantly. Therefore, the issue of how to protect your eyes has become increasingly important in today's era.

[0003] From the perspective of traditional Chinese medicine, the causes of dry eyes and eye fatigue are mainly manifested in the following aspects: Excessive use of the eyes consumes qi and blood, and excessive consumption of liver blood causes dry eyes and eye fatigue. In the book of Chinese medicine theory "Suwen. Xuanming Wuqi Pian", it is mentioned that "long-term viewing hurts blood, long-term lying hurts qi, sitting hurts flesh, long-term standing hurts bones, and long-term walking hurts tendons. These are the five labors referred to by Chinese medicine, which means that excessive use of the eyes will cause different injuries to the body; it also means that as long as the liver can store blood and the blood supply is sufficient, the eyes can be nourished by liver blood, and the vision will be clear and bright; if the liver blood is deficient, it will lead to decreased vision. Because "the liver and kidney have the same origin", the liver and kidney functions are closely related to the eyes. In addition, Chinese medicine also believes that the occurrence of many diseases has a special relationship with the function of human internal organs. For example, if the function of human internal organs is disordered, yin and yang are out of balance, and yang qi is too weak, the divine light cannot be emitted to the outside, and then symptoms such as dry eyes and eye fatigue occur. Therefore, when treating dry eyes and eye fatigue, attention should be paid to regulating the function of internal organs, clearing the orifices and dispersing fire, calming the liver and suppressing yang, clearing the head and eyes, and calming the mind.

[0004] In addition, although there are a wide variety of Chinese herbal eye care products on the market, most of them have poor efficacy, slow onset of effect, and lack scientific experimental verification. Although the use of Chinese herbal decoctions can be adjusted individually according to the actual situation of the patient, Chinese herbal decoctions have a strong taste and may irritate the gastrointestinal tract. They are also inconvenient to carry, resulting in poor compliance with medication and making it difficult for patients to persist in long-term use.

[0005] In view of this, the present invention uses modern pharmacological research methods, conducts in-depth research and screening of classic Chinese medicine prescriptions for treating dry eyes and eye fatigue, and the inventor summarizes long-term clinical diagnosis and treatment experience to develop an external Chinese medicine composition that can effectively relieve dry eyes and eye fatigue. Summary of the invention

[0006] In order to solve the above technical problems, the present invention provides an external Chinese medicine composition for relieving dry eyes and eye fatigue, as well as a preparation method and use thereof.

[0007] Specifically, the present invention is realized through the following technical solutions:

[0008] In the first aspect, the present invention provides a Chinese medicinal composition for external use for relieving dry eyes and eye fatigue, wherein the Chinese medicinal composition is prepared from the following raw materials in parts by weight: 10-60 parts of calcined magnetite, 10-60 parts of mother-of-pearl, 10-60 parts of Cyanobacteria seeds, 5-30 parts of Buddleja flos, 1-20 parts of Tribulus terrestris, 5-30 parts of raw Cassia seeds, 10-60 parts of mint and 1-10 parts of borneol.

[0009] As an optional manner, in the above-mentioned traditional Chinese medicine composition, the traditional Chinese medicine composition is made of the following raw materials in parts by weight: 20-50 parts of calcined magnetite, 20-50 parts of mother of pearl, 20-50 parts of Cyanobacteria seeds, 10-25 parts of Buddleja flos, 5-15 parts of Tribulus terrestris, 10-25 parts of raw Cassia seeds, 20-50 parts of mint and 1-5 parts of borneol.

[0010] As an optional method, in the above-mentioned traditional Chinese medicine composition, the traditional Chinese medicine composition is made of the following raw materials in parts by weight: 40 parts of calcined magnetite, 40 parts of mother-of-pearl, 40 parts of Cyanobacteria seeds, 20 parts of Buddleja flos, 10 parts of Tribulus terrestris, 20 parts of raw Cassia seeds, 40 parts of mint and 3 parts of borneol.

[0011] As an optional mode, in the above-mentioned Chinese medicine composition, the external Chinese medicine composition has the effects of opening all orifices, dispersing stagnant fire, removing cataracts and improving eyesight, calming the liver and suppressing yang, clearing the head and eyes, and calming the nerves and stabilizing the mind.

[0012] In a second aspect, the present invention provides a method for preparing the external Chinese medicine composition according to the first aspect, the preparation method comprising the following steps:

[0013] (1) mixing calcined magnetite, mother-of-pearl, mint and borneol and ultrafine grinding them to prepare mixed ultrafine powder;

[0014] (2) adding water to decoct the seeds of Amaranthus, Buddleja buddleja, Tribulus terrestris, and Cassia seed, decoct for 1-3 hours, filter to obtain a primary filtrate, add water to the residue and decoct for another 1-3 hours, filter to obtain a secondary filtrate, combine the primary filtrate and the secondary filtrate, concentrate to obtain a concentrated solution, dry and grind the concentrated solution into fine powder;

[0015] (3) The mixed ultrafine powder obtained in step (1) and the mixed fine powder obtained in step (2) are fully mixed to obtain the Chinese medicine composition.

[0016] As an optional manner, in the above preparation method, in step (1), the fineness of the ultrafine powder is 100 mesh, and in step (2), the fineness of the fine powder is 40 mesh.

[0017] As an optional manner, in the above preparation method, in step (2), the time for the first decoction and the second decoction are both 1.5 hours.

[0018] In a third aspect, the present invention provides an eye mask for relieving dry eyes and eye fatigue, the eye mask comprising a mask surface, an eye mask lining, an eye mask hole, a medicine bag, an elastic band and a male and female buckle, the mask surface and the eye mask lining are made of silk cloth, the medicine bag is a ring-shaped medicine bag made of cotton cloth with an inner hole diameter of 22-28mm and an outer diameter of 60-70mm, and the medicine bag contains the external Chinese medicine composition described in the first aspect above or the external Chinese medicine composition prepared by the preparation method described in the second aspect above.

[0019] Preferably, the medicine bag is a ring-shaped medicine bag made of cotton cloth with an inner diameter of 25 mm and an outer diameter of 65 mm.

[0020] In a fourth aspect, the present invention provides use of the external Chinese medicine composition described in the first aspect or the external Chinese medicine composition prepared by the preparation method described in the second aspect in the preparation of a drug for relieving dry eyes and eye fatigue.

[0021] As an optional method, in the above-mentioned use, the drug is suitable for the daily care of people who suffer from dry eyes, sore eyes, eye fatigue, eye pain, eye congestion, and blurred vision caused by long-term use of electronic products, studying, and staying up late. It has an auxiliary effect on controlling the increase of eye degree, relieving headaches, insomnia, forgetfulness, irritability, and lack of concentration.

[0022] As an option, in the above use, the medicament is suitable for preventing or treating dry eye.

[0023] As an option, in the above use, the medicament is suitable for preventing or treating myopia.

[0024] Compared with the prior art, the present invention has the following beneficial effects:

[0025] (1) The Chinese medicine composition for external use of the present invention has the effects of opening all the orifices, dispersing stagnant heat, removing cataracts and improving eyesight, calming the liver and suppressing yang, clearing the head and eyes, and calming the mind and stabilizing the spirit.

[0026] (2) The external Chinese medicine composition of the present invention has a simple formulation and reasonable compatibility. The external dosage form allows the active ingredients to be more concentrated in the eyes to take effect, and the therapeutic effect is significant without any toxic side effects.

[0027] (3) The Chinese medicine composition for external use of the present invention is particularly suitable for the daily care of people who suffer from dry eyes, astringent eyes, eye fatigue, eye pain, eye congestion, and blurred vision caused by long-term use of electronic products, study, and staying up late. It has an auxiliary effect on controlling the increase of eye degree, relieving headaches, insomnia, forgetfulness, irritability, and lack of concentration. DETAILED DESCRIPTION

[0028] The efficacy and main treatment of each medicinal ingredient in the Chinese medicine composition of the present invention are as follows:

[0029] The external Chinese medicine composition of the present invention has the effects of opening all the orifices, dispersing stagnant fire, removing cataracts and improving eyesight, calming the liver and suppressing yang, clearing the head and eyes, and calming the mind. Among them, "calcined magnetite" calms the nerves and calms the mind, calms the liver and suppresses yang, improves hearing and improves eyesight, and relieves asthma. "Mother of pearl" calms the liver and suppresses yang, calms the mind and relieves stagnancy, improves eyesight and removes cataracts. "Amaranthus chinensis" clears heat and purges fire, improves eyesight and removes cataracts. "Mint" dispels wind-heat, clears the head and eyes, relieves throat and rashes, and soothes the liver and promotes qi. "Buddleja buddleja" clears heat and purges fire, nourishes the liver and improves eyesight, and removes cataracts. "Raw cassia seed" clears the liver and improves eyesight, moistens the intestines and relieves constipation. "Tribulus terrestris" calms the liver, relieves depression, improves eyesight, and dispels wind. "Borneolum" opens all the orifices, dispersing stagnant fire, removing cataracts and improving eyesight, and relieves swelling and relieves pain.

[0030] The Chinese medicine composition package of the present invention can be placed in a silk eye mask. It is recommended to use the eyes for 30-40 minutes and wear the eye mask for 5 minutes. After removing the eye mask, it is better to use the eye muscle movement chart or augmentation chart. It can be worn for 15-30 minutes before going to bed. The adjustment rope of the eye mask should not be too tight to avoid affecting the blood circulation in the head and causing discomfort. It is not recommended to wear it all night. It is recommended to use each package for about 15 days. The medicine package cannot be disassembled and washed. It is forbidden to be used in patients with eye trauma, inflammation, skin and mucous membrane ulceration, cancer, and severe chronic diseases. Children under 3 years old should use it with caution.

[0031] The present invention will be further described with reference to specific embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the scope of the present invention.

[0032] If no specific techniques or conditions are specified in the examples, the techniques or conditions described in the literature in the field or the product instructions are used. If no manufacturer is specified for the reagents or instruments used, they are all conventional products that can be purchased through regular channels.

[0033] The experimental methods in the following examples are conventional methods unless otherwise specified. The experimental materials used in the following examples are commercially available products unless otherwise specified.

[0034] Preparation Example:

[0035] Embodiment 1:

[0036] A Chinese medicinal composition for external use for relieving dry eyes and eye fatigue, the Chinese medicinal composition being prepared from the following raw materials in parts by weight: 40 parts of calcined magnetite, 40 parts of mother-of-pearl, 40 parts of Celosia chinensis seeds, 20 parts of Buddleja flos, 10 parts of Tribulus terrestris, 20 parts of raw Cassia seeds, 40 parts of mint and 3 parts of borneol.

[0037] The preparation method of the external Chinese medicine composition comprises the following steps:

[0038] (1) calcined magnetite, mother-of-pearl, mint and borneol are mixed and ultrafinely crushed to obtain 100-mesh mixed ultrafine powder;

[0039] (2) adding water to decoct the seeds of Amaranthus, Buddleja Buddleja, Tribulus Terrestris, and Cassia Seed, decoct for 1.5 hours, filter to obtain a primary filtrate, add water to the residue and decoct for another 1.5 hours, filter to obtain a secondary filtrate, combine the primary filtrate and the secondary filtrate, concentrate to obtain a concentrated solution, dry the concentrated solution, and grind it into a 40-mesh fine powder;

[0040] (3) The mixed ultrafine powder obtained in step (1) and the mixed fine powder obtained in step (2) are fully mixed to obtain the Chinese medicine composition.

[0041] Embodiment 2:

[0042] A Chinese medicinal composition for external use for relieving dry eyes and eye fatigue, the Chinese medicinal composition being prepared from the following raw materials in parts by weight: 30 parts of calcined magnetite, 40 parts of mother-of-pearl, 30 parts of Coptidis seeds, 30 parts of Buddleja flos, 10 parts of Tribulus terrestris, 30 parts of raw Cassia seeds, 40 parts of mint and 3 parts of borneol.

[0043] The preparation method is the same as that of Example 1.

[0044] Comparative Example 1:

[0045] A Chinese medicine composition for external use is prepared from the following raw materials in parts by weight: 40 parts of calcined magnetite, 40 parts of mother-of-pearl, 60 parts of gentian seeds, 10 parts of tribulus terrestris, 20 parts of raw cassia seeds, 40 parts of mint and 3 parts of borneol.

[0046] The preparation method is the same as that of Example 1.

[0047] Comparative Example 2:

[0048] A Chinese medicine composition for external use is prepared from the following raw materials in parts by weight: 40 parts of calcined magnetite, 40 parts of mother-of-pearl, 40 parts of Celosia chinensis seeds, 20 parts of Buddleja flos, 10 parts of Tribulus terrestris, 20 parts of Gentiana scabra, 40 parts of mint and 3 parts of borneol.

[0049] The preparation method is the same as that of Example 1.

[0050] Comparative Example 3:

[0051] A Chinese medicine composition for external use is prepared from the following raw materials in parts by weight: 40 parts of calcined magnetite, 40 parts of mother-of-pearl, 40 parts of Celosia chinensis seeds, 20 parts of Buddleja flos, 10 parts of Tribulus terrestris, 20 parts of raw Cassia seeds, 40 parts of mint and 3 parts of borneol.

[0052] The preparation method of the external Chinese medicine composition comprises the following steps:

[0053] Calcined magnetite, mother of pearl, mint, borneol, Cnidium officinale seeds, Buddleja buddleja, Tribulus terrestris and raw Cassia seeds are mixed and ultrafinely ground to obtain 100-mesh mixed ultrafine powder, that is, the traditional Chinese medicine composition is obtained.

[0054] Effect embodiment:

[0055] Effect Example 1: Effect of the external Chinese medicine composition of the present invention on preventing and treating myopia in a guinea pig visual deprivation model

[0056] 1. Experimental Drugs

[0057] An equal amount of the external Chinese medicine composition powder prepared in Examples 1-2 and Comparative Examples 1-3 was added with an equal amount of water to prepare a paste. When used, the paste was covered on a circular non-woven fabric backing and applied around the eyes of experimental guinea pigs.

[0058] 2. Establishment of Animal Model

[0059] 3-week-old healthy tricolor guinea pigs (Heilongjiang University of Traditional Chinese Medicine Experimental Animal Center), weighing 140-160g, 48 males, were adaptively raised for 7 days. Ophthalmological examination confirmed that the experimental animals had no lesions in the anterior segment, clear refractive interstitial tissue, and normal fundus. The experimental animals were randomly divided into a model control group, Example 1 group, Example 2 group, Comparative Example 1 group, Comparative Example 2 group, and Comparative Example 3 group, with 8 animals in each group.

[0060] All guinea pigs were given compound tropicamide eye drops (each 1 mL contains 5 mg of tropicamide and 5 mg of phenylephrine hydrochloride, Santen Pharmaceutical (China) Co., Ltd.) instilled in both eyes, 1 drop was instilled into each eye every 5 minutes, for a total of 4 drops. The refractive power of the guinea pig's left and right eyes was tested and recorded 1 hour after the last instillation. Each eye was tested 3 times, and the average value was calculated and recorded as the refractive power before the experiment.

[0061] The hair on the right side of the midline of the nose of the guinea pig was shaved, and the doughnut-shaped non-woven fabric coated with the paste was applied around the eyes of the experimental animals. The size of the inner ring of the doughnut-shaped non-woven fabric was adjusted appropriately according to the experimental animals. When applying the paste, the extract was not applied within 5 mm of the inner ring to prevent the extract from entering the eyes of the guinea pigs due to the movement of the guinea pigs. The guinea pigs with extracts entering the eyes during the experiment were eliminated. The model group was applied with a blank doughnut-shaped non-woven fabric backing layer. According to the weight of the guinea pig, a milky white latex balloon of appropriate size and thickness of 0.02 mm was selected. The balloon was used to cover the guinea pig's head, and the left eye, ears, and snout were cut off to expose the above parts. During this period, the doughnut-shaped non-woven fabric backing layer should be avoided from moving. After the doughnut-shaped non-woven fabric backing layer was applied for 1 hour, it was removed under light-shielding conditions, and the area around the right eye of the guinea pig was wiped with gauze soaked in physiological saline, dried with a paper towel, and then the balloon was re-covered to ensure that the right eye was blocked and the left eye, ears, and snout were exposed. The dosage was 20 mg paste / 100 g body weight, applied once a day for 4 weeks. The refractive power of the left and right eyes of the guinea pigs in each group was measured again 4 hours after the last application, and recorded as the refractive power after the end of the experiment.

[0062] 3. Statistical analysis methods

[0063] SPSS27.0 statistical software was used for data analysis. The measurement data were expressed as mean ± standard deviation (mean ± SD). One-way ANOVA was used for comparison among multiple groups. LSD test was used for equal variance test, and Euskal-Walli SH method was used for non-parametric test for unequal variance. p < 0.05 was considered statistically significant.

[0064] 4. Experimental Results

[0065] The experimental results of the effect of the external Chinese medicine composition of the present invention on the refractive power of experimental animals in a guinea pig visual deprivation model are shown in Table 1 below.

[0066] Table 1: Effect of the external Chinese medicine composition of the present invention on the diopter of guinea pigs in the visual deprivation model (mean ± SD)

[0067]

[0068] Note: Compared with the ipsilateral eye before the experiment: * p<0.05, ** p<0.01; compared with the contralateral eye after the experiment: # p<0.05, ## p<0.01.

[0069] The experimental results in Table 1 show that there was no statistical difference in the refractive power of the left and right eyes of the guinea pigs in each group before the experiment, but after the experiment, the right eye of the model group rats showed obvious myopia, which was statistically different from the left eye and the right eye before the experiment ( ** p<0.01, ## p<0.01), showing that myopia was successfully induced in the right eye of guinea pigs by occluding the right eye.

[0070] The experimental results of Example 1 and Example 2 show that after the Chinese medicine composition of the present invention is applied externally around the eyes, there is no statistically significant difference in the refractive power of the right eye of the guinea pigs in Example 1 and Example 2 after the experiment compared with the left eye and the right eye before the experiment, which indicates that the external Chinese medicine composition of the present invention has a good preventive and therapeutic effect on myopia, and the effect of the Chinese medicine composition of the present invention in Example 1 group is better.

[0071] The experimental results of Comparative Example 1 to Comparative Example 3 show that removing some of the medicinal flavors of the external Chinese medicine composition of the present invention (see Comparative Example 1), changing the types of some raw materials in the external Chinese medicine composition of the present invention (see Comparative Example 2) and changing the preparation method of the Chinese medicine composition of the present invention (see Comparative Example 3) will all lead to a significant decrease in the efficacy of the external Chinese medicine composition of the present invention in preventing and treating myopia.

[0072] It can be seen that the types and dosage ratios of the raw materials used in the external Chinese medicine composition of the present invention and the preparation method of the external Chinese medicine composition of the present invention have a very significant impact on the efficacy of the external Chinese medicine composition of the present invention in preventing and treating myopia.

[0073] Effect Example 2: Preliminary clinical trial of an eye mask containing the external Chinese medicine composition of the present invention

[0074] 80 volunteers were randomly selected from people who frequently use their eyes, including college students, software engineers, and office workers, and were randomly divided into 4 groups, each with 20 people. The 4 groups of volunteers used eye masks made of the external Chinese medicine compositions of Example 1, Comparative Example 1, Comparative Example 2, and Comparative Example 3 as medicine packs, respectively.

[0075] The volunteers all wore eye masks for 30 minutes before going to bed, and the volunteers were revisited one month after the experiment. The evaluation indicators included the cure of dry eyes, astringent eyes, and eye pain. Cure means that the volunteers no longer have the above symptoms. Cure rate (%) = number of cured people in the group / total number of people in the group × 100%.

[0076] The test results are shown in Table 2 below.

[0077] Table 2: Cure rate (%) of the external Chinese medicine composition of the present invention for dry eyes, astringent eyes, swelling and pain

[0078] Group Dry eyes Eye dryness Eye pain Example 1 Group 100％ 100％ 95％ Comparative Example 1 75％ 65％ 60％ Comparative Example 2 70％ 70％ 60％ Comparative Example 3 85％ 80％ 80％

[0079] As can be seen from Table 2, after using the external Chinese medicine composition of the present invention for one month, the volunteers' symptoms of dry eyes, astringent eyes, and eye pain were basically completely cured. However, the external Chinese medicine compositions of Comparative Example 1 to Comparative Example 3 can only partially relieve the above symptoms of the patient volunteers. This also shows that the types and dosage ratios of the raw materials used in the external Chinese medicine composition of the present invention and the preparation method of the external Chinese medicine composition of the present invention have a very significant effect on the efficacy of the external Chinese medicine composition of the present invention in relieving dry eyes, astringent eyes, and eye pain.

[0080] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. A Chinese medicine composition for external use for relieving dry eyes and eye fatigue, characterized in that: The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-60 parts of calcined magnetite, 10-60 parts of mother-of-pearl, 10-60 parts of gentiana amaranth seeds, 5-30 parts of buddlejac, 1-20 parts of tribulus terrestris, 5-30 parts of raw cassia seeds, 10-60 parts of mint and 1-10 parts of borneol.

2. The external Chinese medicine composition according to claim 1, characterized in that: The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20-50 parts of calcined magnetite, 20-50 parts of mother-of-pearl, 20-50 parts of gentiana amaranth seeds, 10-25 parts of buddlejac, 5-15 parts of tribulus terrestris, 10-25 parts of raw cassia seeds, 20-50 parts of mint and 1-5 parts of borneol.

3. The external Chinese medicine composition according to claim 2, characterized in that: The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 40 parts of calcined magnetite, 40 parts of mother-of-pearl, 40 parts of Cyanobacteria officinalis seeds, 20 parts of Buddleja flos, 10 parts of Tribulus terrestris, 20 parts of raw Cassia seeds, 40 parts of mint and 3 parts of borneol.

4. The external Chinese medicine composition according to claim 1, characterized in that: The external Chinese medicine composition has the effects of opening all orifices, dispersing stagnant fire, removing cataracts and improving eyesight, calming the liver and suppressing yang, clearing the head and eyes, and calming the mind and settling the spirit.

5. The method for preparing the external Chinese medicine composition according to any one of claims 1 to 4, characterized in that: The preparation method comprises the following steps: (1) mixing calcined magnetite, mother-of-pearl, mint and borneol and ultrafine grinding them to prepare mixed ultrafine powder; (2) adding water to decoct the seeds of Amaranthus, Buddleja buddleja, Tribulus terrestris, and Cassia seed, decoct for 1-3 hours, filter to obtain a primary filtrate, add water to the residue and decoct for another 1-3 hours, filter to obtain a secondary filtrate, combine the primary filtrate and the secondary filtrate, concentrate to obtain a concentrated solution, dry and grind the concentrated solution into fine powder; (3) The mixed ultrafine powder obtained in step (1) and the mixed fine powder obtained in step (2) are fully mixed to obtain the Chinese medicine composition.

6. The preparation method according to claim 5, characterized in that: In step (1), the fineness of the ultrafine powder is 100 mesh, and in step (2), the fineness of the fine powder is 40 mesh.

7. The preparation method according to claim 5, characterized in that: In step (2), the first decoction and the second decoction are both performed for 1.5 hours.

8. An eye mask for relieving dry eyes and eye fatigue, characterized by: The eye mask comprises a mask surface, an eye mask lining, an eye mask hole, a medicine bag, an elastic band and a male and female buckle, wherein the mask surface and the eye mask lining are made of silk fabric, the medicine bag is a ring-shaped medicine bag made of cotton fabric with an inner hole diameter of 22-28 mm and an outer diameter of 60-70 mm, and the medicine bag contains the external Chinese medicine composition according to any one of claims 1 to 4 or the external Chinese medicine composition prepared by the preparation method according to any one of claims 5 to 7.

9. Use of the Chinese medicinal composition for external use according to any one of claims 1 to 4 or the Chinese medicinal composition for external use prepared by the preparation method according to any one of claims 5 to 7 in the preparation of a medicament for relieving dry eyes and eye fatigue.

10. The use according to claim 9, characterized in that: The medicine is suitable for daily care of people who suffer from dry eyes, sore eyes, eye fatigue, eye pain, eye congestion and blurred vision caused by long-term use of electronic products, studying and staying up late. It has an auxiliary effect on controlling the increase of eye degree, relieving headache, insomnia, forgetfulness, irritability and inattention.

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