A preparation device and process for bovine colostrum peptide for enhancing immunity

Abstract

The invention discloses a preparation device and process of bovine colostrum peptide for enhancing immunity, belonging to the field of protein peptide preparation, comprising a filter box, wherein a feed port and a discharge port are sequentially arranged on the side wall of the filter box from bottom to top; a bracket is installed in the filter box, a filter membrane is arranged on the bracket, a partition is fixedly installed in the filter box, and through holes are evenly opened on the partition; a linkage box is arranged in the filter box, a reciprocating screw rod is vertically rotatably inserted on the bottom wall of the linkage box, and a slider is threadedly installed on the reciprocating screw rod; through holes are opened in the partition to break up the mixed liquid, so that the impact force on the filter membrane is reduced, and macromolecules are prevented from being tightly attached to the bottom wall of the filter membrane due to the impact force, and the upward-flowing liquid exerts a vertical upward impact force on the macromolecules, and under the action of the arc-shaped frame, the impact force is decomposed along the arc-shaped filter membrane surface, and under the action of the horizontal component force, the macromolecules will automatically slide along the arc-shaped filter membrane surface to the edge of the filter membrane.

Description

Technical Field

[0001] The invention relates to the field of protein peptide preparation, and more specifically to a preparation device and process of bovine colostrum peptide for enhancing immunity. Background Art

[0002] Bovine colostrum has attracted much attention because it contains rich immune active ingredients. It is a natural nutritional supplement and immune regulating substance. Among them, bovine colostrum peptides, as a small molecule peptide substance degraded from bovine colostrum, are rich in immune factors, growth factors, lactoferrin, polypeptides and amino acids, etc., have significant immune regulating effects, and are considered to be an effective raw material for the development of new food additives and health products.

[0003] The preparation process of bovine colostrum peptide includes steps such as raw material selection and pretreatment, enzymatic reaction, enzyme inactivation and separation, concentration and drying. Many of these steps include filtration, which is crucial. It can not only effectively remove impurities, protect production equipment, and improve production efficiency, but also significantly improve product quality and ensure the safety and effectiveness of bovine colostrum peptide.

[0004] The composition of bovine colostrum is complex. In addition to the target active peptides, there are also a large amount of protein, fat, lactose, minerals and other impurities. During the long filtration process, these substances are easy to accumulate on the surface of the filter membrane, causing the pores of the filter membrane to be blocked, the filtration speed to gradually slow down, and even completely unable to continue filtering. The clogging of the filter membrane will seriously affect the separation efficiency, prolong the time of the entire preparation process, and increase production costs. Moreover, in order to ensure the quality and yield of the filtrate, the filter membrane needs to be replaced frequently when it is blocked, which not only increases the complexity of the operation, but also increases the production cost.

[0005] Therefore, a preparation device and process of bovine colostrum peptides for enhancing immunity are proposed. Summary of the invention

[0006] In view of the problems existing in the prior art, the purpose of the present invention is to provide a preparation device and process of bovine colostrum peptides for enhancing immunity, which can improve the filtering effect.

[0007] To solve the above problems, the present invention adopts the following technical solutions.

[0008] A preparation device for bovine colostrum peptides for enhancing immunity, comprising a filter box, wherein a feed inlet and a discharge inlet are sequentially arranged on the side wall of the filter box from bottom to top;

[0009] A bracket is installed in the filter box, a filter membrane is arranged on the bracket, a partition is fixedly installed in the filter box, and through holes are evenly opened on the partition;

[0010] A linkage box is provided in the filter box, a reciprocating screw rod is vertically rotatably inserted on the bottom wall of the linkage box, a slider is threadedly installed on the reciprocating screw rod; and a driving mechanism for driving the reciprocating screw rod to rotate is provided in the filter box;

[0011] A connecting rod is vertically fixedly installed on the bottom wall of the sliding block, and a striking block made of elastic material is arranged on the connecting rod, and the striking block is used to strike the bracket;

[0012] A catheter is vertically rotatably inserted at the center of the top wall of the bracket, a rotating mechanism for driving the catheter to rotate is provided on the catheter, and a one-way valve is embedded in the catheter; a rotating tube is fixedly inserted on the side wall of the catheter, pressure relief holes are evenly opened on the side wall of the rotating tube, and a pressurizing mechanism cooperating with the catheter is provided on the impact block.

[0013] Furthermore, the driving mechanism includes a bevel gear set arranged in the linkage box, the power output shaft of the bevel gear set is fixedly connected to the reciprocating screw, a driving rod with an end extending into the discharge port is fixedly installed on the driving shaft of the bevel gear set, and an impeller is fixedly installed on the end of the driving rod located in the discharge port;

[0014] Among them, the bevel gear set includes a driving gear and a driven gear that mesh with each other. The driving gear is rotatably mounted on the inner side wall of the linkage box, and the driven gear is rotatably mounted on the inner bottom wall of the linkage box. The rotating shaft of the driving gear and the rotating shaft of the driven gear are perpendicular to each other; the rotating shaft of the driven gear is fixedly connected to the reciprocating screw, and the driving rod is mounted on the rotating shaft of the driving gear.

[0015] Furthermore, the longitudinal section of the bracket is arc-shaped; the bottom wall of the bracket is convex downward, and the filter membrane covers the bottom wall of the bracket.

[0016] Further, the impact block includes an upper plate, an elastic block and a lower plate, and the upper plate and the lower plate are fixedly mounted on the top wall and the bottom wall of the elastic block respectively;

[0017] The pressurizing mechanism comprises a groove arranged on the bottom wall of the elastic block, a hole connected with the groove is arranged on the lower plate, and a water inlet valve connected with the filter box is embedded on the side wall of the groove.

[0018] Furthermore, the rotating mechanism includes drainage holes evenly opened on the side wall of the conduit, the drainage holes are evenly distributed circumferentially on the same horizontal plane, and the drainage holes are inclined, and the ratio of the sum of the longitudinal cross-sectional areas of the multiple drainage holes to the end area of ​​the rotating tube is 0.5-0.8.

[0019] Furthermore, cavities are evenly opened on the bracket, a first spring is fixedly installed on the side wall of the cavity, a magnetic block is fixedly installed on the end of the first spring, and the rotating tube is made of a magnetic material that repel the magnetic block.

[0020] Further, the bracket includes a mounting frame and an arc frame, the mounting frame is rotatably mounted in the filter box, the arc frame is fixedly mounted on the bottom wall of the mounting frame, the conduit is mounted on the top wall of the arc frame, the filter membrane is mounted on the bottom wall of the arc frame, and the rotating tube is in contact with the top wall of the arc frame;

[0021] An inner gear ring is fixedly mounted on the inner side wall of the mounting frame, an outer gear ring is fixedly mounted on the reciprocating screw rod, and a linkage mechanism for rotating the inner gear ring and the outer gear ring simultaneously is arranged in the filter box.

[0022] Furthermore, the linkage mechanism includes a mounting plate rotatably mounted on the bottom wall of the linkage box, and sockets are evenly arranged on the side walls of the mounting plate. Insertion rods are slidably mounted in the insertion holes, and an elastic rope is installed between the insertion rod and the end surface of the insertion hole. A motor with an output end connected to the center of the top wall of the mounting plate is fixedly installed in the linkage box, and a trigger mechanism for controlling the start and stop of the motor is provided on the filter box.

[0023] Furthermore, the trigger mechanism includes a first pressure detection module and a second pressure detection module respectively arranged in the feed port and the discharge port, and a calculation module and a control module are arranged on the filter box;

[0024] The first pressure detection module and the second pressure detection module send the detected data to the calculation module;

[0025] The calculation module sends the calculation result to the control module;

[0026] The control module is used to control the start and stop of the motor.

[0027] The present invention also provides a preparation process of bovine colostrum peptide for enhancing immunity, comprising the following steps:

[0028] S1. First, install the filter membrane on the bracket, then install the bracket in the filter box, and then inject the mixed liquid to be filtered and separated into the feed inlet;

[0029] S2, the mixed liquid fills the space below the partition and is discharged through the through hole, and the liquid level in the filter box gradually passes through the filter membrane;

[0030] S3, the liquid filtered by the filter membrane is discharged through the discharge port, and the liquid flowing in the discharge port impacts the impeller, driving the driving rod and the bevel gear set to work, so that the slider drives the impact block to intermittently impact the bracket;

[0031] S4. After the impact block impacts the bracket, the groove provides high-pressure liquid to the catheter and the rotating tube. At this time, the catheter drives the rotating tube to rotate, and at the same time, the rotating tube discharges high-pressure liquid through the pressure relief hole to pass through the bracket to impact the filter membrane, exerting a horizontal impact force on the filter membrane, and at the same time impacting the macromolecules under the filter membrane, so that the macromolecules move in the horizontal direction and break away from the filter membrane;

[0032] S5. When the trigger mechanism detects that the filter membrane is clogged, the motor starts, driving the bracket and the reciprocating screw to rotate.

[0033] Compared with the prior art, the present invention has the following beneficial effects:

[0034] (1) By opening through holes in the partition to break up the mixed liquid, the impact force on the filter membrane is reduced, preventing the macromolecules from being tightly attached to the bottom wall of the filter membrane due to the impact force. The upward flowing liquid exerts a vertical upward impact force on the macromolecules. Under the action of the arc frame, the impact force is decomposed along the arc-shaped filter membrane surface. Under the action of the horizontal component force, the macromolecules will automatically slide along the arc-shaped filter membrane surface to the edge of the filter membrane;

[0035] (2) The bottom wall area of ​​the convex filter membrane is larger than the cross-sectional area of ​​the filter box, which increases the contact area between the mixed liquid and the filter membrane, thereby reducing the load on the filter membrane, that is, preventing the macromolecules in the mixed liquid from continuously impacting a certain part of the filter membrane, reducing the probability of filter membrane clogging, improving the filtration effect, and playing a role in improving work efficiency;

[0036] And the working efficiency is improved without increasing the volume of the filter box, which plays a role in saving costs;

[0037] (3) The impeller drives the reciprocating screw to rotate through the bevel gear set. When the slider moves downward, the impact block first hits the conduit, and then the slider continues to move downward until it moves to the lowest position; when the downward impact block hits the conduit, the impact force is transmitted to the macromolecules attached to the surface of the filter membrane through the bracket and the filter membrane, so that the attached macromolecules can be subjected to the downward impact force, causing the macromolecules to break away from the filter membrane. At this time, the coverage of the macromolecules on the surface of the filter membrane is reduced, the permeability of the filter membrane is improved, and the filtration efficiency is improved;

[0038] (4) In this scheme, the upward-flowing liquid exerts a vertical upward impact force on the macromolecules on the surface of the filter membrane through the coordination of the arc-shaped support and the filter membrane. Under the action of the horizontal component force, the macromolecules will automatically slide along the arc-shaped filter membrane surface to the edge of the filter membrane, thereby achieving the function of automatically cleaning the filter membrane; the bottom wall area of ​​the filter membrane in a raised state is larger than the cross-sectional area of ​​the filter box, which increases the contact area between the mixed liquid and the filter membrane, thereby reducing the load on the filter membrane, that is, preventing the macromolecules in the mixed liquid from continuously impacting a certain part of the filter membrane, reducing the probability of filter membrane clogging, improving the filtration effect, and playing a role in improving work efficiency; and the work efficiency is improved without increasing the volume of the filter box. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0040] Figure 2It is a cross-sectional structural schematic diagram of the filter box of the present invention;

[0041] Figure 3 It is a schematic diagram of the combined structure of the inner gear ring and the outer gear ring of the present invention;

[0042] Figure 4 For the present invention Figure 2 A schematic diagram of the enlarged structure at A in the middle;

[0043] Figure 5 For the present invention Figure 2 A schematic diagram of the enlarged structure at B in the middle;

[0044] Figure 6 For the present invention Figure 2 Schematic diagram of the enlarged structure at C in the middle;

[0045] Figure 7 It is a schematic cross-sectional structural diagram of the arc frame of the present invention;

[0046] Figure 8 is a schematic cross-sectional structural diagram of the catheter of the present invention;

[0047] Fig. 9 This is a working flow chart of the first pressure detection module, the second pressure detection module, the calculation module and the control module of the present invention.

[0048] Description of the numbers in the figure:

[0049] 1. Filter box; 2. Bracket; 201. Mounting frame; 202. Arc frame; 3. Filter membrane; 4. Partition; 5. Linkage box; 6. Reciprocating screw; 7. Sliding block; 8. Linking rod; 9. Impact block; 901. Upper plate; 902. Elastic block; 903. Lower plate; 10. Conduit; 11. One-way valve; 12. Rotating tube; 13. Pressure relief hole; 14. Bevel gear set; 15. Driving rod; 16. Impeller; 17. Groove; 18. Hole; 19. Inlet valve; 20. Drain hole; 21. Sponge; 22. First spring; 23. Magnetic block; 24. Inner gear ring; 25. Outer gear ring; 26. Mounting plate; 27. Insert rod; 28. Elastic rope; 29. ​​Motor; 30. First pressure detection module; 31. Second pressure detection module; 32. Calculation module; 33. Control module. DETAILED DESCRIPTION

[0050] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention; it is obvious that the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments, and all other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making creative work are within the scope of protection of the present invention.

[0051] Embodiment 1:

[0052] See also Figures 1 to 9 , a preparation device of bovine colostrum peptide for enhancing immunity, comprising a filter box 1, on the side wall of which a feed inlet and a discharge inlet are arranged in sequence from bottom to top;

[0053] A support 2 is installed in the filter box 1, and holes are evenly opened on the support 2. A filter membrane 3 is arranged on the support 2. A partition 4 is fixedly installed in the filter box 1, and the partition 4 is located between the feed port and the discharge port. Through holes are evenly opened on the partition 4.

[0054] A linkage box 5 is provided in the filter box 1, and a reciprocating screw 6 is vertically rotatably inserted on the bottom wall of the linkage box 5, and a slider 7 is threadedly installed on the reciprocating screw 6. A guide rod is movably inserted on the slider 7, and the guide rod is parallel to the reciprocating screw 6, and the guide rod is fixed to the bottom wall of the linkage box 5. Therefore, during the rotation of the reciprocating screw 6, the moving direction of the slider 7 is limited by the guide rod, so that the slider 7 can make up and down reciprocating motions along the reciprocating screw 6. Both forward and reverse motions can make the slider 7 reciprocate along the reciprocating screw 6. These are all prior arts and will not be described in detail; and a driving mechanism for driving the reciprocating screw 6 to rotate is provided in the filter box 1;

[0055] A linkage rod 8 is vertically fixedly mounted on the bottom wall of the slider 7, and a collision block 9 made of elastic material is provided on the linkage rod 8, and the collision block 9 is used to impact the bracket 2;

[0056] A catheter 10 is vertically rotatably inserted at the center of the top wall of the bracket 2, and a rotating mechanism for driving the catheter 10 to rotate is provided on the catheter 10. A one-way valve 11 is embedded in the catheter 10, and the output end cooperates with the rotating tube 12. The liquid passing through the one-way valve 11 will flow into the rotating tube 12; a rotating tube 12 is fixedly inserted on the side wall of the catheter 10, and the rotating tube 12 is in contact with the top wall of the bracket 2. Pressure relief holes 13 are evenly opened on the side wall of the rotating tube 12, and a pressurizing mechanism cooperating with the catheter 10 is provided on the impact block 9.

[0057] The filter membrane 3 is an ultrafiltration membrane 3, the pore size of the ultrafiltration membrane 3 is between 0.001 and 0.1 microns, and can remove substances with larger molecular weights, such as protein, fat, lactose, etc.

[0058] The driving mechanism includes a bevel gear set 14 arranged in the linkage box 5, the power output shaft of the bevel gear set 14 is fixedly connected to the reciprocating screw 6, and a driving rod 15 with an end extending into the discharge port is fixedly installed on the driving shaft of the bevel gear set 14, and an impeller 16 is fixedly installed on the end of the driving rod 15 located in the discharge port.

[0059] Among them, the bevel gear set 14 includes a driving gear and a driven gear that mesh with each other. The driving gear is rotatably mounted on the inner side wall of the linkage box 5, and the driven gear is rotatably mounted on the inner bottom wall of the linkage box 5. The rotating shaft of the driving gear and the rotating shaft of the driven gear are perpendicular to each other; the rotating shaft of the driven gear is fixedly connected to the reciprocating screw 6, and the driving rod 15 is mounted on the rotating shaft of the driving gear.

[0060] The longitudinal section of the bracket 2 is arc-shaped; the bottom wall of the bracket 2 is convex downward, and the filter membrane 3 covers the bottom wall of the bracket 2, so the filter membrane 3 is in an arc-shaped state convex downward.

[0061] First, a mixed liquid of bovine colostrum is injected into the feed port, and the liquid level of the mixed liquid in the space below the partition 4 gradually rises, and finally overflows through the evenly distributed through holes, so that the mixed liquid discharged from the feed port can be broken up. When the mixed liquid contacts the filter membrane 3, the impact force on the filter membrane 3 is reduced, which prevents the macromolecules from being tightly attached to the bottom wall of the filter membrane 3 due to the impact force, causing the filter membrane 3 to be blocked, thereby improving the filtering effect of the filter membrane 3. As the liquid level in the filter box 1 rises, water, inorganic salts, small molecule peptides, etc. pass through the filter membrane 3, and macromolecules such as protein, fat, and lactose are blocked on the bottom wall of the filter membrane 3, thereby achieving the separation effect of bovine colostrum peptides and improving the purity and quality of bovine colostrum peptides. At the same time, the separated bovine colostrum peptides are discharged through the discharge port along with the liquid.

[0062] For the macromolecules attached to the bottom wall of the filter membrane 3, the liquid flowing upward under the filter membrane 3 exerts a vertical upward impact force on the macromolecules, and the impact force is decomposed along the curved surface of the filter membrane 3. Under the action of the horizontal component force, the macromolecules will automatically slide along the curved surface of the filter membrane 3 to the edge of the filter membrane 3, thereby achieving the effect of automatically cleaning the surface of the filter membrane 3.

[0063] The bottom wall area of ​​the filter membrane 3 in the raised state is larger than the cross-sectional area of ​​the filter box 1, which increases the contact area between the mixed liquid and the filter membrane 3, thereby reducing the load of the filter membrane 3, that is, preventing the macromolecules in the mixed liquid from continuously impacting a certain part of the filter membrane 3, reducing the probability of clogging of the filter membrane 3, improving the filtering effect, and playing a role in improving work efficiency;

[0064] Moreover, the working efficiency is improved without increasing the volume of the filter box 1, thus playing a role in saving costs.

[0065] The liquid flowing in the discharge port impacts the impeller 16, and the impeller 16 drives the bevel gear set 14 to work through the driving rod 15. The output end of the bevel gear set 14 drives the reciprocating screw 6 to rotate. At this time, the slider 7 drives the connecting rod 8 to reciprocate up and down. When the slider 7 moves downward, the impact block 9 first hits the conduit 10, and then the slider 7 continues to move downward until it moves to the lowest position; since the bracket 2 is fixedly installed, after the impact block 9 hits the bracket 2, the downward moving connecting rod 8 and the bracket 2 squeeze the impact block 9, and the impact block 9 is deformed at this time.

[0066] When the downwardly moving impact block 9 hits the conduit 10, the impact force is transmitted to the macromolecules attached to the surface of the filter membrane 3 through the bracket 2 and the filter membrane 3, so that the attached macromolecules can be subjected to the downward impact force, causing the macromolecules to break away from the filter membrane 3. At this time, the coverage of the macromolecules on the surface of the filter membrane 3 is reduced, the permeability of the filter membrane 3 is improved, and the filtering efficiency is improved; at the same time, under the action of the pressurizing mechanism, the liquid in the conduit 10 is in a high-pressure state, and the liquid in the conduit 10 is discharged through the pressure relief holes 13 on the side wall of the rotating tube 12. At this time, the macromolecules that are out of contact with the filter membrane 3 are subjected to the impact force of the liquid discharged from the pressure relief holes 13, so that this part of the macromolecules is subjected to a horizontal thrust, so that this part of the macromolecules quickly moves to the edge of the bracket 2, thereby improving the permeability of the filter membrane 3 and further improving the filtering efficiency.

[0067] like Figure 5 As shown, the impact block 9 includes an upper plate 901, an elastic block 902 and a lower plate 903. The upper plate 901 and the lower plate 903 are respectively fixedly mounted on the top wall and the bottom wall of the elastic block 902. The linkage rod 8 is rotatably inserted on the upper plate 901 to facilitate the rotation of the catheter 10.

[0068] The pressurizing mechanism includes a groove 17 formed on the bottom wall of the elastic block 902, and a hole 18 communicating with the groove 17 is formed on the lower plate 903;

[0069] When the lower plate 903 is not in contact with the bracket 2, the elastic block 902 is in a natural state, and the hole 18 is aligned with the top of the catheter 10. After the lower plate 903 hits the catheter 10, the slider 7 drives the upper plate 901 to continue to move downward, the lower plate 903 is blocked, and the elastic block 902 is squeezed;

[0070] At this time, the liquid in the groove 17 enters the conduit 10 , and then, as the upper plate 901 moves downward, the pressure in the conduit 10 gradually increases, thereby playing a role in pressurizing the conduit 10 .

[0071] A water inlet valve 19 connected to the filter box 1 is embedded on the side wall of the groove 17; therefore, when the slider 7 moves upward, the groove 17 can absorb liquid through the water inlet valve 19, thereby ensuring that the slider 7 can move upward normally.

[0072] like Figure 4 , Figure 5 As shown, the rotating mechanism includes drainage holes 20 evenly opened on the side wall of the conduit 10, the drainage holes 20 are evenly distributed in a circle on the same horizontal plane, and the drainage holes 20 are inclined, and the ratio of the sum of the longitudinal cross-sectional areas of the plurality of drainage holes 20 to the end area of ​​the rotating tube 12 is 0.5-0.8.

[0073] When the liquid in the groove 17 enters the conduit 10, the liquid in the conduit 10 passes through the one-way valve 11. At this time, part of the liquid that passes through the one-way valve 11 enters the rotating tube 12, and the remaining liquid is discharged through the drainage hole 20. Since the drainage hole 20 is arranged obliquely, the conduit 10 drives the rotating tube 12 to rotate under the action of the reaction force of the liquid discharged from the drainage hole 20, so that the pressure relief holes 13 on the side wall of the rotating tube 12 can impact multiple parts of the filter membrane 3, thereby improving the cleaning effect of the macromolecules on the bottom wall of the filter membrane 3 and further improving the work efficiency.

[0074] like Figure 4 As shown, a sponge 21 is fixedly mounted on the bottom wall of the bracket 2 . The sponge 21 is annular and is sleeved on the outer wall of the filter membrane 3 .

[0075] When macromolecules move along the surface of the filter membrane 3, they will move into the small holes on the sponge 21. Therefore, when the liquid surface in the filter box 1 shakes, the shaking amplitude of the macromolecules gathered in the sponge 21 can be reduced, thereby reducing the possibility of these macromolecules moving to the surface of the filter membrane 3 again with the liquid.

[0076] like Figure 7 As shown, cavities are evenly opened on the bracket 2, a first spring 22 is fixedly installed on the side wall of the cavity, a magnetic block 23 is fixedly installed on the end of the first spring 22, and the rotating tube 12 is made of a magnetic material that repel the magnetic block 23.

[0077] When the rotating tube 12 is away from the cavity, under the action of the first spring 22, the magnetic block 23 is not in contact with the side wall of the cavity;

[0078] During the rotation of the rotating tube 12, when the rotating tube 12 moves to the surface of the cavity, under the action of the repulsive force between the rotating tube 12 and the magnetic block 23, the magnetic block 23 hits the bottom wall of the cavity, and the first spring 22 is deformed. When the rotating tube 12 moves away from the cavity, the first spring 22 recovers, and under the action of inertia, the magnetic block 23 drives the first spring 22 to swing up and down. During this process, the magnetic block 23 intermittently hits the bottom wall of the cavity, thereby providing impact force to the filter membrane 3 for a long time, thereby improving the cleaning effect of the macromolecules on the surface of the filter membrane 3.

[0079] like Figure 4As shown, the bracket 2 includes a mounting frame 201 and an arc frame 202, the mounting frame 201 is rotatably mounted in the filter box 1, the arc frame 202 is fixedly mounted on the bottom wall of the mounting frame 201, the conduit 10 is mounted on the top wall of the arc frame 202, the filter membrane 3 is mounted on the bottom wall of the arc frame 202, and the rotating tube 12 is in contact with the top wall of the arc frame 202;

[0080] An inner gear ring 24 is fixedly mounted on the inner side wall of the mounting frame 201 , an outer gear ring 25 is fixedly mounted on the reciprocating screw rod 6 , and a linkage mechanism is provided in the filter box 1 to enable the inner gear ring 24 and the outer gear ring 25 to rotate simultaneously.

[0081] The linkage mechanism includes a mounting plate 26 rotatably mounted on the bottom wall of the linkage box 5, and insertion holes are evenly opened on the side walls of the mounting plate 26. A plug rod 27 is slidably installed in the insertion hole, and an elastic rope 28 is installed between the plug rod 27 and the end surface of the plug hole. A motor 29 connected to the output end and the center of the top wall of the mounting plate 26 is fixedly installed in the linkage box 5, and a trigger mechanism for controlling the start and stop of the motor 29 is provided on the filter box 1.

[0082] When the mounting plate 26 is not rotating, under the action of the elastic rope 28, the insertion rod 27 is located in the insertion hole, that is, the insertion rod 27 is out of contact with the inner gear ring 24 and the outer gear ring 25, ensuring that the impeller 16 can drive the reciprocating screw 6 to rotate normally; when the trigger mechanism detects that a large amount of macromolecular substances are attached to the surface of the filter membrane 3, the trigger mechanism controls the motor 29 to work, and at this time the motor 29 drives the mounting plate 26 to rotate.

[0083] When the mounting plate 26 rotates at high speed, under the action of centrifugal force, the insertion rod 27 extends from the insertion hole, and the corresponding insertion rod 27 extends into the corresponding tooth grooves of the inner gear ring 24 and the outer gear ring 25, thereby pushing the inner gear ring 24 and the outer gear ring 25 to rotate.

[0084] When the inner gear ring 24 rotates, it drives the support 2 to rotate, thereby providing centrifugal force for the macromolecules attached to the surface of the filter membrane 3, throwing the macromolecules away, and improving the cleaning effect of the filter membrane 3;

[0085] When the outer gear ring 25 rotates, it drives the reciprocating screw 6 to rotate rapidly, increasing the frequency of the impact block 9 impacting the catheter 10, thereby increasing the impact force on the macromolecular substances on the surface of the filter membrane 3, and further improving the cleaning effect of the filter membrane 3.

[0086] By setting the driving gear and the driven gear to the same model and size, the driven gear can also drive the driving gear to rotate. Therefore, during the rotation of the outer ring gear 25, the impeller 16 can be driven to reverse through the bevel gear set 14. At this time, the discharge speed of the discharge port is reduced, and the impeller 16 applies pressure to the liquid in the discharge port, increasing the pressure in the space above the filter membrane 3 in the filter box 1, thereby reducing the pressure difference between the top and bottom of the filter membrane 3, reducing the upward pressure on the large molecules on the surface of the filter membrane 3, and further improving the cleaning effect on the large molecules.

[0087] like Figure 1 , Figure 2 As shown, the trigger mechanism includes a first pressure detection module 30 and a second pressure detection module 31 respectively arranged in the feed port and the discharge port, and a calculation module 32 and a control module 33 are arranged on the filter box 1;

[0088] The first pressure detection module 30 and the second pressure detection module 31 send the detected data to the calculation module 32; the first pressure detection module 30 and the second pressure detection module 31 are pressure sensors of the same model;

[0089] The calculation module 32 sends the calculation result to the control module 33;

[0090] The control module 33 is used to control the start and stop of the motor 29.

[0091] When the surface of the ultrafiltration membrane 3 is blocked by macromolecules, the resistance of water flowing through the membrane will increase, resulting in an increase in the pressure difference between the inlet and outlet of the membrane. Therefore, by detecting the pressure difference between the feed inlet and the discharge port, it is possible to understand whether the ultrafiltration membrane 3 is blocked.

[0092] By installing pressure sensors at the feed inlet and the discharge outlet, the pressure on the upper and lower sides of the ultrafiltration membrane 3 is monitored respectively, and the pressure difference between the two is calculated. If the pressure difference exceeds the initial value of 0.05MPa, it means that the fluid resistance has increased significantly and the surface of the ultrafiltration membrane 3 is blocked by macromolecules;

[0093]

[0094] Wherein, B is the pressure difference, which is the preset value;

[0095] P1 is the pressure value of the discharge port;

[0096] P2 is the feed inlet pressure value.

[0097] The present invention also provides a preparation process of bovine colostrum peptide for enhancing immunity, comprising the following steps:

[0098] S1. First, install the filter membrane 3 on the bracket 2, then install the bracket 2 in the filter box 1, and then inject the mixed liquid to be filtered and separated into the feed inlet;

[0099] S2, the mixed liquid fills the space below the partition 4 and is discharged through the through hole, and the liquid level in the filter box 1 gradually passes through the filter membrane 3;

[0100] S3, the liquid filtered by the filter membrane 3 is discharged through the discharge port, and the liquid flowing in the discharge port impacts the impeller 16, driving the driving rod 15 and the bevel gear set 14 to work, so that the slider 7 drives the impact block 9 to intermittently impact the bracket 2;

[0101] S4. After the impact block 9 impacts the support 2, the groove 17 provides high-pressure liquid to the conduit 10 and the rotating tube 12. At this time, the conduit 10 drives the rotating tube 12 to rotate, and at the same time, the rotating tube 12 discharges high-pressure liquid through the pressure relief hole 13 to pass through the support 2 to impact the filter membrane 3, exerting a horizontal impact force on the filter membrane 3, and at the same time impacting the macromolecules under the filter membrane 3, so that the macromolecules move in the horizontal direction and break away from the filter membrane 3;

[0102] S5. When the trigger mechanism detects that the filter membrane 3 is clogged, the motor 29 starts to drive the bracket 2 and the reciprocating screw 6 to rotate.

[0103] The above is only a preferred specific implementation of the present invention; however, the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical solution and its improved conception within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A device for preparing bovine colostrum peptides for enhancing immunity, comprising a filter box (1), wherein a feed inlet and a discharge outlet are sequentially arranged on the side wall of the filter box (1) from bottom to top; Features: A support (2) is installed in the filter box (1), a filter membrane (3) is provided on the support (2), a partition (4) is fixedly installed in the filter box (1), and through holes are evenly opened on the partition (4); The filter box (1) is provided with a linkage box (5), a reciprocating screw rod (6) is vertically rotatably inserted on the bottom wall of the linkage box (5), and a slider (7) is threadedly mounted on the reciprocating screw rod (6); and a driving mechanism for driving the reciprocating screw rod (6) to rotate is provided in the filter box (1); A linkage rod (8) is vertically fixedly mounted on the bottom wall of the sliding block (7), and a collision block (9) made of elastic material is provided on the linkage rod (8), and the collision block (9) is used to collide with the bracket (2); A conduit (10) is vertically rotatably inserted at the center of the top wall of the bracket (2); a rotating mechanism for driving the conduit (10) to rotate is provided on the conduit (10); a one-way valve (11) is embedded in the conduit (10); a rotating tube (12) is fixedly inserted on the side wall of the conduit (10); pressure relief holes (13) are evenly opened on the side wall of the rotating tube (12); and a pressurizing mechanism cooperating with the conduit (10) is provided on the impact block (9).

2. The device for preparing bovine colostrum peptides for enhancing immunity according to claim 1, characterized in that: The driving mechanism comprises a bevel gear set (14) arranged in a linkage box (5); a power output shaft of the bevel gear set (14) is fixedly connected to a reciprocating screw (6); a driving rod (15) whose end extends into a discharge port is fixedly mounted on the driving shaft of the bevel gear set (14); an impeller (16) is fixedly mounted on the end of the driving rod (15) located in the discharge port; The bevel gear set (14) comprises a driving gear and a driven gear meshing with each other, the driving gear is rotatably mounted on the inner side wall of the linkage box (5), the driven gear is rotatably mounted on the inner bottom wall of the linkage box (5), the rotating shaft of the driving gear and the rotating shaft of the driven gear are perpendicular to each other; the rotating shaft of the driven gear is fixedly connected to the reciprocating screw (6), and the driving rod (15) is mounted on the rotating shaft of the driving gear.

3. The device for preparing bovine colostrum peptides for enhancing immunity according to claim 2, characterized in that: The longitudinal section of the support (2) is arc-shaped; the bottom wall of the support (2) is convex downward, and the filter membrane (3) covers the bottom wall of the support (2).

4. The device for preparing bovine colostrum peptides for enhancing immunity according to claim 3, characterized in that: The impact block (9) comprises an upper plate (901), an elastic block (902) and a lower plate (903), wherein the upper plate (901) and the lower plate (903) are respectively fixedly mounted on the top wall and the bottom wall of the elastic block (902); The pressurizing mechanism comprises a groove (17) formed on the bottom wall of the elastic block (902); a hole (18) communicating with the groove (17) is formed on the lower plate (903); and a water inlet valve (19) communicating with the filter box (1) is embedded on the side wall of the groove (17).

5. The device for preparing bovine colostrum peptide for enhancing immunity according to claim 4, characterized in that: The rotating mechanism comprises drainage holes (20) uniformly arranged on the side wall of the guide tube (10), the drainage holes (20) being uniformly distributed circumferentially on the same horizontal plane, the drainage holes (20) being arranged obliquely, and the ratio of the sum of the longitudinal cross-sectional areas of the plurality of drainage holes (20) to the end area of ​​the rotating tube (12) being 0.5-0.

8.

6. The device for preparing bovine colostrum peptides for enhancing immunity according to claim 5, characterized in that: The bracket (2) is evenly provided with cavities, a first spring (22) is fixedly mounted on the side wall of the cavity, a magnetic block (23) is fixedly mounted on the end of the first spring (22), and the rotating tube (12) is made of a magnetic material that repel the magnetic block (23).

7. The device for preparing bovine colostrum peptides for enhancing immunity according to claim 6, characterized in that: The support (2) comprises a mounting frame (201) and an arc frame (202); the mounting frame (201) is rotatably mounted in the filter box (1); the arc frame (202) is fixedly mounted on the bottom wall of the mounting frame (201); the guide tube (10) is mounted on the top wall of the arc frame (202); the filter membrane (3) is mounted on the bottom wall of the arc frame (202); and the rotating tube (12) is in contact with the top wall of the arc frame (202); An inner gear ring (24) is fixedly mounted on the inner side wall of the mounting frame (201), an outer gear ring (25) is fixedly mounted on the reciprocating screw rod (6), and a linkage mechanism is provided in the filter box (1) for causing the inner gear ring (24) and the outer gear ring (25) to rotate simultaneously.

8. The device for preparing bovine colostrum peptides for enhancing immunity according to claim 7, characterized in that: The linkage mechanism comprises a mounting plate (26) rotatably mounted on the bottom wall of the linkage box (5), the side wall of the mounting plate (26) is evenly provided with insertion holes, a plug rod (27) is slidably mounted in the insertion hole, an elastic rope (28) is installed between the plug rod (27) and the end surface of the insertion hole, and a motor (29) whose output end is connected to the center of the top wall of the mounting plate (26) is fixedly mounted in the linkage box (5), and a trigger mechanism for controlling the start and stop of the motor (29) is provided on the filter box (1).

9. The device for preparing bovine colostrum peptides for enhancing immunity according to claim 8, characterized in that: The trigger mechanism comprises a first pressure detection module (30) and a second pressure detection module (31) respectively arranged in the feed port and the discharge port, and the filter box (1) is provided with a calculation module (32) and a control module (33); The first pressure detection module (30) and the second pressure detection module (31) send the detected data to the calculation module (32); The calculation module (32) sends the calculation result to the control module (33); The control module (33) is used to control the start and stop of the motor (29).

10. A process for preparing a bovine colostrum peptide for enhancing immunity according to any one of claims 1 to 9, characterized in that: The steps include: S1. First, install the filter membrane (3) on the bracket (2), then install the bracket (2) in the filter box (1), and then inject the mixed liquid to be filtered and separated into the feed inlet; S2, the mixed liquid fills the space below the partition (4) and is discharged through the through hole, and the liquid level in the filter box (1) gradually passes through the filter membrane (3); S3, the liquid filtered by the filter membrane (3) is discharged through the discharge port, and the liquid flowing in the discharge port impacts the impeller (16), driving the driving rod (15) and the bevel gear set (14) to work, so that the slider (7) drives the impact block (9) to intermittently impact the bracket (2); S4. After the impact block (9) impacts the support (2), the groove (17) provides high-pressure liquid to the conduit (10) and the rotating tube (12). At this time, the conduit (10) drives the rotating tube (12) to rotate, and at the same time, the rotating tube (12) discharges the high-pressure liquid through the pressure relief hole (13) through the support (2) to impact the filter membrane (3), exerting a horizontal impact force on the filter membrane (3), and at the same time impacting the macromolecules under the filter membrane (3), so that the macromolecules move in the horizontal direction and break away from the filter membrane (3); S5. When the trigger mechanism detects that the filter membrane (3) is clogged, the motor (29) starts, driving the bracket (2) and the reciprocating screw (6) to rotate.

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