Automatic filling device for milrinone raw material medicine injection processing

By designing an automatic filling device for Milinon raw materials, the pollution caused by manual filling and cover buckle in the prior art and the low drug pass rate is solved, automated production is achieved, and efficiency and quality are improved.

CN119750477APending Publication Date: 2025-04-04JIANGSU LIANHUAN PHARMA +1
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Patent Information

Application Number
CN202510256665.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-05
Publication Date
2025-04-04

AI Technical Summary

Technical Problem

There are problems of manual filling and cover buckle in the production of existing Milinnong raw materials, resulting in low contamination and low drug pass rate.

Method used

An automatic filling device is designed, including a silo, suction pump, rotary drum, annular plate and a gland hydraulic mechanism to realize automatic filling, sealing and glanding of the gland.

Benefits of technology

The automated production of Milinong raw material injections has been realized, manual operations have been reduced, production efficiency and drug quality have been improved, and the stability and reliability of the production process have been ensured.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses an automatic filling device for milrinone bulk drug injection processing. The automatic filling device comprises a base, a stock bin is arranged in the base, a supporting column is arranged at the upper end of the stock bin, and a top plate is installed at the upper end of the supporting column; a material suction pump is further installed at the bottom of the supporting column, the material suction end of the material suction pump extends into the stock bin, a material suction pipe connected with the material suction pump is installed in the supporting column and the top plate, and a material injection opening connected with the material suction pipe is further formed in the lower end of the top plate. A center hole is formed in the middle of the rotary drum, and a plurality of barrel cover containing grooves are evenly formed around the center hole at intervals. Through cooperation of all the mechanism parts, the automatic filling function of the milrinone raw material medicine injection material barrel and the capping and capping functions of the material barrel can be achieved, overall automatic engineering is achieved, manpower and material resources are saved, the working efficiency and the working quality are effectively improved, the structure is stable and reliable, and the automatic filling machine is very suitable for industrial production.
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Description

Technical Field

[0001] The invention relates to the technical field of processing and production of milrinone raw material medicine, in particular to an automatic filling device used for processing milrinone raw material medicine injection. Background Art

[0002] In the prior art, milrinone, whose chemical name is 1,6-dihydro-2-methyl-6-oxo-[3,4'-bipyridine]-5-carbonitrile, is an organic compound with a chemical formula of C12H9N3O and is clinically used for chronic congestive heart failure and refractory heart failure.

[0003] At present, the general production process of milrinone in general units is cleaning-sterilization-filling-packaging. Since some manufacturers use manual filling in production, it is easy to cause pollution. In addition, in the capping step after filling, the sealing of the raw material barrel after sterilization is not good, and the raw material manufacturers often use manual capping during the production process, which is easy to cause secondary pollution and result in a low drug qualification rate.

[0004] Therefore, in order to solve the above problems, it is necessary to develop an automatic filling device for the processing of milrinone raw material injections that has a reasonable structure and can realize automatic filling and capping. Summary of the invention

[0005] The purpose of the present invention is to provide an automatic filling device for the processing of milrinone raw material injection in view of the shortcomings of the prior art; the technical scheme is as follows:

[0006] An automatic filling device for processing milrinone raw material injection comprises a base, a silo is arranged in the base, a support column is arranged at the upper end of the silo, a top plate is installed at the upper end of the support column; a suction pump is also installed at the bottom of the support column, the suction end of the suction pump extends into the silo, a suction pipe connected to the suction pump is installed in the support column and the top plate, and a material injection port connected to the suction pipe is also installed at the lower end of the top plate;

[0007] It also includes a rotating drum, a central hole is provided at the middle position of the rotating drum, a plurality of bucket cover placement grooves are provided around the central hole at even intervals, the support column passes through the central hole of the rotating drum, and a fixed baffle connected to the support column is also installed at the lower end of the rotating drum, the fixed baffle blocks the lower end of the bucket cover placement groove, and a first rotating mechanism is also provided at the lower end of the rotating drum, and the rotating drum is driven to rotate around the support column accordingly through the first rotating mechanism;

[0008] The outside of the rotating drum is also provided with a circle of annular plates, which are arranged concentrically with the rotating drum, and are provided with a second rotating mechanism and a limiting mechanism, and the cooperation of the second rotating mechanism and the limiting mechanism drives the annular plate to rotate accordingly; and the annular plate is also provided with a plurality of evenly spaced barrel placement turntables, and the lower end surface of the annular plate is correspondingly provided with a turntable rotating motor for use with the turntable;

[0009] The top plate is also provided with a capping mechanism and a capping mechanism corresponding to the position of the barrel cover placement groove.

[0010] Furthermore, the capping mechanism comprises a capping rotary motor installed on the lower end surface of the top plate, a rotary arm installed on the main shaft of the capping rotary motor, and a capping hydraulic mechanism installed on the end of the rotary arm; the hydraulic rod of the capping hydraulic mechanism extends vertically downward, and a suction cup is installed at the end of the rod, and a vacuum pump is installed corresponding to the suction cup through a pipeline;

[0011] The suction cup is located directly above the barrel cover placement groove. The suction cup can move up and down under the control of the capping hydraulic mechanism, and can suck the barrel cover in the capping placement groove under the action of the vacuum pump. After sucking the barrel cover, it can be rotated and adjusted in position under the action of the capping rotating motor, so that the suction cup is located directly above the outer barrel placement turntable, and the capping hydraulic mechanism controls the suction cup to move downward to cover the barrel cover on the barrel.

[0012] Furthermore, the capping mechanism comprises a capping hydraulic mechanism installed on the lower end surface of the top plate, a hydraulic rod of the capping hydraulic mechanism extends vertically downward and a pressing wheel is installed at the end of the shaft, and the position of the pressing wheel corresponds to the edge of the barrel cover of the barrel on the turntable where the barrel is placed;

[0013] When the barrel cover is covered on the barrel, the cover pressing hydraulic mechanism drives the pressing wheel to move down, and the pressing wheel presses on the edge of the barrel cover. At this time, the turntable rotating motor drives the barrel to place the turntable and the barrel to rotate, pressing and fixing the barrel cover on the barrel.

[0014] Furthermore, the first rotating mechanism includes a first meshing gear ring extending downwardly from the lower end of the rotating drum and a first rotating motor, on which a first meshing gear is mounted, and the first meshing gear is mounted correspondingly to the first meshing gear ring, thereby realizing the rotation of the rotating drum.

[0015] Furthermore, the second rotating mechanism includes a second meshing gear ring arranged at the outer end of the annular plate and extending downward, and a second rotating motor, on which a second meshing gear is installed, and the second meshing gear is installed correspondingly to the second meshing gear ring, thereby realizing the rotation of the annular plate.

[0016] Furthermore, the limiting structure includes an annular slider installed on the lower end surface of the annular plate and a fixed annular slide rail, and the annular slider is embedded in the annular slide rail.

[0017] Furthermore, the fixed baffle is also provided with a through hole that is compatible with the position and size of the barrel cover placement slot, a lifting mechanism is installed below the through hole, and a support plate is installed on the main shaft of the lifting mechanism. The support plate extends from the through hole into the barrel cover placement slot to lift the barrel cover in the barrel cover placement slot accordingly.

[0018] Furthermore, the barrel placement turntable is also provided with positioning grooves, and the barrels are correspondingly placed in the positioning grooves.

[0019] Furthermore, a positioning frame corresponding to the position of the barrel placement turntable is also provided on the annular plate, and the positioning frame is configured as a semicircular fence structure, surrounding the outer side of the barrel placement turntable.

[0020] Beneficial effects: The present invention has the following beneficial effects:

[0021] 1) The present invention can realize the automatic filling function of the barrel in the milrinone raw material injection and the capping and pressing functions of the barrel through the cooperation of various mechanism components, realize the overall automation project, save manpower and material resources, effectively improve work efficiency and work quality, have a stable and reliable structure, and is very suitable for industrial production;

[0022] 2) In the present invention, the barrel cover is placed in the barrel cover placement slot in the rotating drum, and the lifting mechanism drives the support plate to move up to lift the barrel cover upward, so as to facilitate the suction of the suction cup of the capping mechanism. When the barrel cover in one barrel cover placement slot is used, the rotating drum can be driven to rotate by the second rotating mechanism to replace another barrel cover placement slot for use, so as to facilitate the loading of the barrel cover and improve the processing efficiency;

[0023] 3) In the present invention, by placing the barrel on the barrel placing turntable, the suction pump sucks the material in the silo into the injection port, and injects the material into the barrel through the injection port to complete the filling. Then, the second rotating mechanism drives the annular plate to rotate as a whole, and brings the barrel to the bottom of the capping mechanism, so as to facilitate the filling of the material;

[0024] 4) In the present invention, the capping work of the barrel cover can be realized by the capping mechanism, and the barrel cover can be pressed and fixed by the capping mechanism. The structure is reasonable, the use is convenient, and the work is efficient. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a structural diagram of the present invention;

[0026] Figure 2 It is the front view of the present invention;

[0027] Figure 3 This is a structural diagram of the rotary drum in the present invention;

[0028] Figure 4 This is a diagram showing the position of the fixed baffle in the present invention;

[0029] Figure 5 for Figure 2 Exploded view;

[0030] Figure 6 It is a structural diagram of the cover pressing mechanism in the present invention;

[0031] Figure 7 for Figure 2 Middle AA section view. DETAILED DESCRIPTION

[0032] The present invention is further explained below in conjunction with the accompanying drawings and specific embodiments. The embodiments are implemented based on the technical solution of the present invention. It should be understood that these embodiments are only used to illustrate the present invention and are not used to limit the scope of the present invention.

[0033] like Figure 1 and Figure 2 As shown, an automatic filling device for processing milrinone raw material injection comprises a base 35, a silo 7 is arranged in the base 35, a support column 3 is arranged at the upper end of the silo 7, a top plate 1 is installed at the upper end of the support column 3; a suction pump 5 is also installed at the bottom of the support column 3, the suction end of the suction pump 5 extends into the silo 7, a suction pipe connected to the suction pump 5 is installed in the support column 3 and the top plate 1, and a material injection port 2 connected to the suction pipe is also installed at the lower end of the top plate 1;

[0034] like Figure 3 and Figure 4 As shown, it also includes a rotating drum 4, a central hole 12 is provided at the middle position of the rotating drum 4, a plurality of bucket cover placement grooves 21 are provided around the central hole 12 with uniform intervals, the support column 3 passes through the central hole 12 of the rotating drum 4, and a fixed baffle 28 connected to the support column 3 is also installed at the lower end of the rotating drum 4, the fixed baffle 28 blocks the lower end of the bucket cover placement groove 21, and a first rotating mechanism is also provided at the lower end of the rotating drum 4, and the rotating drum 4 is driven to rotate around the support column 3 accordingly through the first rotating mechanism;

[0035] A ring plate 6 is also arranged outside the rotating drum 4, and the ring plate 6 is arranged concentrically with the rotating drum 4. The ring plate 6 is provided with a second rotating mechanism and a limiting mechanism, and the ring plate 6 is driven to rotate accordingly through the cooperation of the second rotating mechanism and the limiting mechanism; and a plurality of evenly spaced barrel placement turntables 22 are also installed on the ring plate 6, and a turntable rotating motor 13 used in conjunction is correspondingly installed on the lower end surface of the ring plate 6;

[0036] The top plate 1 is also provided with a capping mechanism and a capping mechanism corresponding to the position of the barrel cover placement groove 21 .

[0037] like Figure 5 and Figure 6As shown, the capping mechanism includes a capping rotary motor 20 installed on the lower end surface of the top plate 1, a rotary arm 17 installed on the main shaft of the capping rotary motor 20, and a capping hydraulic mechanism 19 installed on the end of the rotary arm 17; the hydraulic rod of the capping hydraulic mechanism 19 extends vertically downward, and a suction cup 14 is installed at the end of the rod, and the suction cup 14 is correspondingly installed with a vacuum pump 15 through a pipeline;

[0038] The suction cup 14 is located directly above the barrel cover placement groove 21. The suction cup 14 can move up and down under the control of the capping hydraulic mechanism 19, and can suck the barrel cover in the capping placement groove under the action of the vacuum pump 15. After sucking the barrel cover, it can be rotated and adjusted in position under the action of the capping rotating motor 20, so that the suction cup 14 is located directly above the outer barrel placement turntable 22, and the capping hydraulic mechanism 19 controls the suction cup 14 to move downward to cover the barrel cover on the barrel.

[0039] The capping mechanism includes a capping hydraulic mechanism 11 installed on the lower end surface of the top plate 1, the hydraulic rod of the capping hydraulic mechanism 11 extends vertically downward and a pressing wheel 10 is installed at the shaft end, and the position of the pressing wheel 10 corresponds to the edge of the barrel cover of the barrel on the barrel placement turntable 22;

[0040] After the barrel cover is covered on the barrel, the cover pressing hydraulic mechanism 11 drives the pressing wheel 10 to move downward, and the pressing wheel 10 presses on the edge of the barrel cover. At this time, the turntable rotating motor 13 drives the barrel placement turntable 22 and the barrel to rotate, pressing and fixing the barrel cover on the barrel.

[0041] like Figure 7 As shown, the first rotating mechanism includes a first meshing gear ring 34 extending downward from the lower end of the rotating drum 4 and a first rotating motor 30, on which a first meshing gear 31 is installed. The first meshing gear 31 is installed corresponding to the first meshing gear ring 34, thereby realizing the rotation of the rotating drum 4.

[0042] The second rotating mechanism includes a second meshing gear ring 26 which is arranged at the outer end of the annular plate 6 and extends downward, and a second rotating motor 32, on which a second meshing gear 33 is mounted. The second meshing gear 33 is mounted corresponding to the second meshing gear ring 26, thereby realizing the rotation of the annular plate 6.

[0043] The limiting structure includes an annular slider 25 installed on the lower end surface of the annular plate 6 and a fixed annular slide rail 26 , and the annular slider 25 is embedded in the annular slide rail 26 .

[0044] The fixed baffle 28 is also provided with a through hole 29 which is adapted to the position and size of the barrel cover placement groove 21. A lifting mechanism 8 is installed below the through hole 29. A support plate 9 is installed on the main shaft of the lifting mechanism 8. The support plate 9 extends from the through hole 29 into the barrel cover placement groove 21 to lift the barrel cover in the barrel cover placement groove 21 accordingly.

[0045] The barrel placement turntable 22 is also provided with positioning grooves 16 , and the barrels are placed in the positioning grooves 16 accordingly.

[0046] A positioning frame 18 corresponding to the position of the barrel placement turntable 22 is also provided on the annular plate 6 . The positioning frame 18 is configured as a semicircular fence structure and surrounds the outer side of the barrel placement turntable 22 .

[0047] The specific working principle and process of the present invention are as follows: when the device is used, the material barrel needs to be placed on the material barrel placing turntable first. The material barrel placing turntable is provided with a positioning groove, and the material barrel can be directly placed in the positioning groove. Then, the second rotating motor is turned on, and the second meshing gear on the second rotating motor drives the second meshing gear ring on the annular plate of the outer ring to rotate, thereby driving the annular plate to rotate and moving the material barrel to the bottom of the injection port.

[0048] At this time, the suction pump is turned on to suck the material in the silo and then input it into the filling port through the suction pipe, and then poured downward from the filling port into the barrel to complete the filling of the barrel. After that, the annular plate is continued to be rotated by the second rotating mechanism to move the filled barrel to the position corresponding to the capping mechanism and the pressing mechanism.

[0049] First, the barrel is capped through the capping mechanism. After the capping rotating motor is turned on, it drives the rotary arm to rotate, and moves the capping hydraulic mechanism and the suction cup to the top of the barrel cover placement slot. There are many stacked barrel covers placed in each barrel cover placement slot. Then, the suction cup is driven downward by the capping hydraulic mechanism. The suction cup generates suction under the action of the vacuum pump, thereby sucking the suction cup. Then, the capping rotating mechanism drives the rotary arm to rotate to the top of the barrel, and then the suction cup is driven downward by the capping hydraulic mechanism to place the barrel cover on the barrel to complete the capping process. However, at this time, the barrel cover is only covered on the barrel and is not pressed tightly, so it is necessary to press the barrel cover tightly.

[0050] After the barrel cover is covered on the barrel, the cover hydraulic mechanism controls the pressure wheel to press down and press on the edge of the barrel, and at this time, the turntable rotation motor is controlled to start to drive the barrel placement turntable to rotate. After the barrel placement turntable rotates, it drives the barrel to rotate as well, and the pressure wheel pressed on the barrel cover above rotates accordingly. After one rotation, the barrel cover is pressed tightly on the barrel, and when the barrel placement turntable rotates, since the pressure wheel above is pressed on the edge of the barrel cover, there is a risk of the barrel tipping over. In order to prevent the barrel from tipping over or the position being not stable enough, the present invention also provides a corresponding positioning frame on the annular plate, and the positioning frame is a fence-type structure and is semicircular. When the barrel rotates accordingly, the barrel will not tip over due to the protection of the positioning frame on the outside, and the barrel as a whole is very convenient to take and put.

[0051] In the process of the capping mechanism sucking the barrel cover from the barrel cover placement groove through the suction cup, a through hole is also provided on the fixed baffle plate, and a supporting plate extends from the through hole into the barrel cover placement groove to lift the barrel cover. When the barrel cover is sucked, the lifting mechanism drives the supporting plate to move up, so that the barrel cover moves up, ensuring that the suction cup can suck the barrel cover. When the barrel cover in the barrel cover placement groove is used up, the second rotating mechanism drives the rotating drum to rotate, and moves the other barrel cover placement groove to the corresponding position of the capping mechanism, ensuring smooth operation.

[0052] The above specific implementation is only a preferred embodiment of the present invention and is not intended to limit the implementation of the present invention and the scope of the claims. All equivalent changes and modifications made according to the content of the patent protection scope of the present invention should be included in the scope of the patent application of the present invention.

Claims

1. An automatic filling device for the processing of milrinone raw material injection, characterized in that: The invention comprises a base (35), wherein a material bin (7) is arranged in the base (35), a support column (3) is arranged at the upper end of the material bin (7), and a top plate (1) is installed at the upper end of the support column (3); a suction pump (5) is also installed at the bottom of the support column (3), and the suction end of the suction pump (5) extends into the material bin (7); a suction pipe connected to the suction pump (5) is installed in the support column (3) and the top plate (1), and a material injection port (2) connected to the suction pipe is also installed at the lower end of the top plate (1); The invention also comprises a rotating drum (4), wherein a central hole (12) is provided at a middle position of the rotating drum (4), and a plurality of bucket cover placement grooves (21) are provided around the central hole (12) at even intervals. The support column (3) passes through the central hole (12) of the rotating drum (4), and a fixed baffle (28) connected to the support column (3) is installed at the lower end of the rotating drum (4), wherein the fixed baffle (28) blocks the lower end of the bucket cover placement groove (21). A first rotating mechanism is also provided at the lower end of the rotating drum (4), and the rotating drum (4) is driven to rotate around the support column (3) by the first rotating mechanism. The outside of the rotating drum (4) is also provided with a ring plate (6), the ring plate (6) is arranged concentrically with the rotating drum (4), and the ring plate (6) is provided with a second rotating mechanism and a limiting mechanism, and the ring plate (6) is driven to rotate accordingly through the cooperation of the second rotating mechanism and the limiting mechanism; and a plurality of evenly spaced material barrel placement turntables (22) are also installed on the ring plate (6), and a turntable rotating motor (13) for use with the turntable is correspondingly installed on the lower end surface of the ring plate (6); The top plate (1) is also provided with a capping mechanism and a capping mechanism corresponding to the position of the barrel cover placement groove (21).

2. The automatic filling device for processing milrinone raw material injection according to claim 1, characterized in that: The capping mechanism comprises a capping rotary motor (20) mounted on the lower end surface of the top plate (1), a rotary arm (17) mounted on the main shaft of the capping rotary motor (20), and a capping hydraulic mechanism (19) mounted on the end of the rotary arm (17); a hydraulic rod of the capping hydraulic mechanism (19) extends vertically downward, and a suction cup (14) is mounted on the end of the rod, and a vacuum pump (15) is mounted on the suction cup (14) via a pipeline. The suction cup (14) is located directly above the barrel cover placement groove (21). The suction cup (14) can move up and down under the control of the capping hydraulic mechanism (19), and can suck the barrel cover in the capping placement groove under the action of the vacuum pump (15). After sucking the barrel cover, the suction cup (14) can be rotated and adjusted in position under the action of the capping rotating motor (20), so that the suction cup (14) is located directly above the outer barrel placement turntable (22). The capping hydraulic mechanism (19) controls the suction cup (14) to move downward so that the barrel cover is covered on the barrel.

3. The automatic filling device for processing milrinone raw material injection according to claim 2, characterized in that: The capping mechanism comprises a capping hydraulic mechanism (11) mounted on the lower end surface of the top plate (1), a hydraulic rod of the capping hydraulic mechanism (11) extending vertically downward and a pressing wheel (10) mounted on the shaft end, and the position of the pressing wheel (10) corresponds to the edge of the barrel cover on the barrel placement turntable (22); After the barrel cover is placed on the barrel, the cover pressing hydraulic mechanism (11) drives the pressing wheel (10) to move downward, and the pressing wheel (10) presses on the edge of the barrel cover. At this time, the turntable rotating motor (13) drives the barrel placement turntable (22) and the barrel to rotate, so that the barrel cover is pressed and fixed on the barrel.

4. The automatic filling device for processing milrinone raw material injection according to claim 1, characterized in that: The first rotating mechanism comprises a first meshing gear ring (34) and a first rotating motor (30) arranged at the lower end of the rotating drum (4) and extending downward. The first rotating motor (30) is mounted with a first meshing gear (31). The first meshing gear (31) and the first meshing gear (34) are mounted correspondingly to each other, thereby realizing the rotation of the rotating drum (4).

5. The automatic filling device for processing milrinone raw material injection according to claim 1, characterized in that: The second rotating mechanism comprises a second meshing gear ring (26) arranged at the outer end of the annular plate (6) and extending downward, and a second rotating motor (32), a second meshing gear (33) being mounted on the second rotating motor (32), and the second meshing gear (33) being mounted correspondingly to the second meshing gear ring (26), thereby realizing the rotation of the annular plate (6).

6. The automatic filling device for processing milrinone raw material injection according to claim 1, characterized in that: The limiting structure comprises an annular slider (25) mounted on the lower end surface of the annular plate (6) and a fixed annular slide rail (26), wherein the annular slider (25) is embedded in the annular slide rail (26).

7. The automatic filling device for processing milrinone raw material injection according to claim 1, characterized in that: The fixed baffle plate (28) is further provided with a through hole (29) whose position and size match the barrel cover placement groove (21); a lifting mechanism (8) is installed below the through hole (29); a supporting plate (9) is installed on the main shaft of the lifting mechanism (8); the supporting plate (9) extends from the through hole (29) into the barrel cover placement groove (21) to lift the barrel cover in the barrel cover placement groove (21) accordingly.

8. The automatic filling device for processing milrinone raw material injection according to claim 1, characterized in that: The barrel placement turntable (22) is also provided with a positioning groove (16), and the barrel is correspondingly placed in the positioning groove (16).

9. The automatic filling device for processing milrinone raw material injection according to claim 8, characterized in that: The annular plate (6) is also provided with a positioning frame (18) corresponding to the position of the barrel placement turntable (22); the positioning frame (18) is configured as a semicircular fence structure and surrounds the outer side of the barrel placement turntable (22).

Citation Information

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