Use of hydrocarbons and isomers thereof as pest control composition and pest control method

Abstract

The invention discloses an application of a hydrocarbon and / or an isomer thereof as a pest control composition, and the hydrocarbon is an alkane with the carbon number of 10-16. As the hydrocarbon and / or the isomer thereof have insecticidal activity, an effective amount of the hydrocarbon and the isomer thereof disclosed by the invention are applied or introduced into a space, so that the hydrocarbon and the isomer thereof are indirectly or directly contacted with the pests, and the effect of poisoning and killing the pests can be effectively achieved.

Description

Technical Field

[0001] The present invention relates to a second use of hydrocarbons, and in particular to a use of hydrocarbons and isomers thereof as a pest control composition and a method for controlling pests. Background Art

[0002] Currently, approved insect control compositions include phosphine, methyl bromide and sulfuryl fluoride. Although they are effective in controlling pests, they are also toxic to humans and animals or destructive to the environment. For example, although methyl bromide has good insecticidal ability, it is destructive to the ozone layer and has been clearly regulated by the Montreal Protocol to be used only in customs quarantine and its usage should be reduced year by year. Phosphine is a substitute for methyl bromide and has excellent insecticidal toxicity, but it is extremely toxic to humans and animals and must be used in accordance with operating specifications. Although sulfuryl fluoride has a control effect on termites or other pests in buildings, studies have shown that its ability to cause a greenhouse effect is about 4,800 times that of carbon dioxide and has the potential to accelerate global warming.

[0003] Existing pest control compositions are harmful to environmental sustainability and / or human and animal health, but the demand for pest control continues to exist. Therefore, the global pest control market is in urgent need of a new pest control composition that is highly safe for humans and animals and friendly to the environment. Summary of the invention

[0004] The main purpose of the present invention is to provide a use of hydrocarbons and their isomers as pest control compositions. Since the active ingredients composed of hydrocarbons and / or their isomers have the characteristics of being non-toxic, safe and environmentally friendly, they can replace the currently used known pesticides or environmental medicines.

[0005] Another object of the present invention is to provide a method for pest control. Since hydrocarbons and / or their isomers can kill pests by directly or indirectly contacting the pests, they can be widely used in various environmental or agricultural pesticides.

[0006] Therefore, in order to achieve the above-mentioned purpose, the present invention discloses a use of a hydrocarbon and / or its isomers as a pest control composition, wherein the hydrocarbon is an alkane, and its carbon number is a positive integer between greater than or equal to 10 and less than or equal to 16. Specifically, since the vapor of the hydrocarbon and / or its isomers disclosed in the present invention has the activity of poisoning and killing a variety of pests, the hydrocarbon and / or its isomers disclosed in the present invention can be used as the main active ingredient in the pest control composition for poisoning and killing pests.

[0007] Among them, the pest control composition disclosed in the present invention can poison and kill a variety of pests, including rice weevils, two-spotted spider mites, tobacco beetles, German cockroaches, long-legged ants, invasive red fire ants, and mosquito larvae (wriggler), and can therefore be used in crop pest control, environmental pest control, etc.

[0008] In one embodiment of the present invention, the hydrocarbon has an even number of carbon atoms, such as n-decane, n-dodecane, n-tetradecane and n-hexadecane; and corresponding to the above compounds, the isomers of the hydrocarbon may be isodecane, isododecane, isotetradecane and isohexadecane.

[0009] The isodecane is an isomer of n-decane and has different structural formulas according to the different positions of its functional groups, such as 2-methylnonacan.

[0010] The isododecane is an isomer of n-dodecane and has different structural formulas according to the different positions of its functional groups, such as 2,2,4,6,6-pentamethylheptane and 2-methylundecane.

[0011] The isotetradecane is an isomer of n-tetradecane and has different structural formulas according to the different positions of its functional groups, such as 2-methyltridecane.

[0012] Among them, isohexadecane is an isomer of n-hexadecane, and has different structural formulas depending on the positions of its functional groups, such as 2,2,4,4,6,8,8-heptamethylnonane.

[0013] In an embodiment of the present invention, the pest control composition is in the form of a fumigant, a spray or a solution. When the pest control composition is in the form of a fumigant, the dosage of the pest control composition is a fumigation using not less than 5 mg of hydrocarbons and / or their isomers in a space of one liter. The hydrocarbons and / or their isomers have a better toxic effect at a dosage of 30 mg or more.

[0014] In another embodiment of the present invention, a method for pest control is disclosed, which comprises providing an effective amount of a pest control composition or its vapor into a space, wherein the active ingredient in the pest control composition is an effective amount of the above-mentioned hydrocarbon and / or its isomer, and the effective amount of the hydrocarbon and / or its isomer is at least 2.5 mg or more, preferably 5 mg or more, in a space with a volume of one liter.

[0015] The beneficial effects of the present invention are:

[0016] The use of hydrocarbons and their isomers as pest control compositions and pest control methods provided by the present invention are non-toxic, safe and environmentally friendly, and can kill pests by directly or indirectly contacting the pests. Therefore, the hydrocarbons and their isomers can replace currently used known pesticides or environmental medicines, or be applied to various environmental medicines or agricultural medicines. DETAILED DESCRIPTION

[0017] The present invention discloses the use of hydrocarbons and / or their isomers as pest control compositions, wherein the hydrocarbons are alkanes with carbon numbers of 10 to 16, are non-toxic to humans, animals and the environment, and have the activity of killing pests, so they can be used as active ingredients of pest control compositions; in other words, by applying an effective amount of the hydrocarbons and their isomers disclosed in the present invention, or a pest control composition containing any of the above compounds to a space, an object in the space, or pests in the space, the effect of killing pests in the space can be effectively achieved.

[0018] The space may be an open field or a closed field, wherein when the space is a closed field, the effect of killing pests will be better.

[0019] In an embodiment of the present invention, the hydrocarbon or its isomer is volatile and can directly or indirectly contact the pest or its body, thereby causing the pest to lose its activity or die. For example, the hydrocarbon or its isomer disclosed in the present invention has the activity of killing at least one pest in vapor form, so the hydrocarbon or its isomer can be placed in a space, and the hydrocarbon or its isomer is volatilized into the space, so that the pest inhales it and kills the pest.

[0020] In an embodiment of the present invention, the hydrocarbon is n-decane, n-dodecane, n-tetradecane or n-hexadecane.

[0021] In an embodiment of the present invention, the isomer of the hydrocarbon is an isoparaffin, such as isodecane, isododecane, and isotetradecane.

[0022] The pest control composition disclosed in the present invention can be prepared into different dosage forms, such as fumigants, sprays, liquid dosage forms, solid volatile dosage forms, etc., according to factors such as usage requirements, usage sites, and user objects; and the effective amount of the hydrocarbon or its isomer in the pest control composition will vary according to different dosage forms, but it will not exceed the scope of protection of the claims of this case due to changes in effective amounts such as dosage or concentration. In addition, in order to be able to prepare different dosage forms, the pest control composition further includes an agriculturally acceptable component, such as a spreader, a solvent, etc.

[0023] For example, when the pest control composition is a fumigant, the effective amount of the hydrocarbon and its isomers means that not less than 5 mg of hydrocarbon and its isomers are placed in one liter of space, such as 5 mg, 10 mg, 15 mg, 20 mg, 30 mg.

[0024] When the pest control composition is a spray or a liquid, the effective amount of the hydrocarbon and its isomers is at least 2.5 mg in a space of one liter.

[0025] The term "alkanes" is also known as alkanes. The overall structure is mainly composed of carbon and hydrogen, and the carbon-carbon and carbon-hydrogen are only bonded by single bonds.

[0026] The term "n-decane", also known as n-decane, decane, has a molecular formula of C 10 H 22 The structural formula is shown in the following formula (I). n-Decadecane is a non-polar molecule and one of the components of gasoline.

[0027]

[0028] The term "n-dodecane", also known as dodecane, has a molecular formula of C 12 H 26 The structural formula is shown in the following formula (II). n-Dodecane is a viscous, colorless, odorless, oily liquid.

[0029]

[0030] The term "n-tetradecane", also known as tetradecane, has a molecular formula of C 14 H 30 The structural formula is shown in the following formula (III). n-Tetradecane is a non-polar molecule insoluble in water and exists in petroleum.

[0031]

[0032] The term "n-hexadecane", also known as hexadecane, has a molecular formula of C 16 H 34, the structural formula is shown in the following formula (IV). n-Hexadecane is a white solid or colorless liquid, which is soluble in ether or petroleum ether, but insoluble in water.

[0033]

[0034] The term "isomer" refers to molecules with the same molecular formula but different structural formulas, and they have the same functional groups. Therefore, isomers with different structures have similar or identical properties.

[0035] The term "isodecane" refers to an isomer of n-decane. 2-methylnonane represented by the following formula (V) is a type of isodecane.

[0036]

[0037] The term "isododecane" refers to an isomer of n-dodecane. For example, 2,2,4,6,6-pentamethylheptane as shown in the following formula (VI), 2-methylundecane as shown in the following formula (VII), and 3-methylundecane as shown in the following formula (VIII) belong to isododecane.

[0038]

[0039]

[0040] The term "isotetradecane" refers to an isomer of n-tetradecane. For example, 2-methyltridecane shown in the following formula (IX) is an isotetradecane.

[0041]

[0042] The term "isohexadecane" refers to an isomer of n-hexadecane. For example, 2,2,4,4,6,8,8-heptamethylnonane (2,2,4,4,6,8,8-heptamethylnonane) as shown in the following formula (X) belongs to isohexadecane.

[0043]

[0044] The term "pest" refers to organisms that have adverse effects on humans and human activities, such as causing harm to crops, animals or trees, or spreading diseases that endanger human health. Pests include insects or non-insects, such as rice weevils, two-spotted spider mites, tobacco beetles, German cockroaches, long-legged ants, invasive red fire ants, and mosquito larvae.

[0045] The term "space" refers to the field used to apply the hydrocarbons and isomers thereof disclosed in the present invention, which can be formed by natural environment, such as an ant nest; artificially constructed, such as a closed space or a closed greenhouse built with a tent; or a place without clear demarcation lines but with a specific purpose, such as a playground, farmland, etc.

[0046] The term "fumigant" refers to a composition that uses vapor or gas generated by the volatilization of the active ingredients contained therein to kill insects. The dosage used varies according to the toxicity of the active ingredients, the type of insects, the size of the fumigation site, and other parameters. In the present invention, the main active ingredient in the fumigant is at least one compound of the hydrocarbon compound and its isomers disclosed in the present invention.

[0047] The term "spray" refers to a formulation that converts a liquid into a mist by high pressure or compressed air. When the pest control composition disclosed in the present invention is a spray, the hydrocarbon and its isomers can actively or passively contact the pest body in the form of a mist, wherein the so-called "active" means that the mist is directly sprayed onto the insect body; the so-called "passive" means that the mist is sprayed on any surface in the space or on an object therein, and the pest stays or crawls through the place and contacts the mist.

[0048] The term "spreader", also known as surfactant, is a chemical substance that has both hydrophilicity and lipophilicity and can be used to assist in the emulsification, dispersion, fixation and spreading of the active ingredients in the pest control composition disclosed in the present invention.

[0049] The term "agricultural spreader" refers to agriculturally acceptable spreaders.

[0050] The term "agriculturally acceptable ingredients" refers to ingredients that comply with any domestic or international standards or are common knowledge and can be used in agricultural or environmental medicines, such as surfactants, organic solvents, etc.

[0051] The term "effective amount" refers to a dosage or concentration that can effectively kill insects in a space, and the effective amount will vary with the dosage form, use field, application object, etc.

[0052] The compounds used in the following examples are all commercially available.

[0053] Example 1: Insecticidal test (I)

[0054] Rice weevil (Sitophilus oryzae), two-spotted spider mite (Tetranychus urticae), tobacco beetle (Lasioderma serricorne), German cockroach (Blattella germanica), long-legged ant (Anoplolepis longipes), and invasive red fire ant (Solenopsis invicta) were respectively placed in 1L containers as test objects, and then carriers containing different concentrations (2.5, 5, 10, 20, 30, 40 mg) of isododecane (2,2,4,6,6-pentamethylheptane) were placed in the 1L containers. The containers were sealed and steamed for 24 hours. After aeration, the number of dead insects was confirmed and the mortality rate was calculated. The results are shown in Table 1 below.

[0055] Table 1: The mortality rate of isododecane at different concentrations to different pests

[0056]

[0057] The results in Table 1 above show that fumigation with isododecane at a concentration of 5 mg or more has a toxic effect on various pests, among which the toxic effect on two-spotted spider mites is the best; and when the isododecane concentration is 30 mg or more, the toxic effect on various pests reaches 100%.

[0058] Example 2: Insecticidal test (II)

[0059] Rice weevils, two-spotted spider mites, tobacco beetles, German cockroaches, long-legged ants, and invasive red fire ants were placed in 1L containers respectively, and then carriers containing 30mg of n-dodecane, n-decane, 2-methylnonacan (isodecane), and 2,2,4,6,6-pentamethylheptane (isododecane) were placed in the 1L containers respectively. The containers were sealed and steamed for 24 hours. After aeration, the number of dead insects was confirmed and the mortality rate was calculated. The results are shown in Table 2 below.

[0060] Table 2: The mortality rate of different compounds (concentration 30 μL) against different pests

[0061]

[0062] From the results in Table 2, it can be seen that n-decane, n-dodecane and their isomers have obvious toxic effects on various pests, especially isododecane has the best toxic effect on various pests.

[0063] Example 3: Insecticidal test (III)

[0064] 30 mosquito larvae (wrigglers) raised artificially without pathogens were placed in a 1L container with 100 ml of deionized water. Different doses of isododecane and isohexadecane were added in a ratio of 4:1 to agricultural spreader. The mixture was evenly mixed without covering. After 24 hours, the number of dead mosquito larvae was confirmed and the mortality rate was calculated. The results are as follows

[0065] Table 3: The mortality rate of isododecane and isohexadecane to mosquito larvae at different doses

[0066]

[0067] From the results in Table 3, it can be seen that the toxic effects of isododecane and isohexadecane on mosquito larvae (mosquito larvae) are both above 2.5 mg per 100 ml of water, with a mortality rate of more than 50%.

Claims

1. A use of a hydrocarbon and / or its isomers as a pest control composition, characterized in that: The hydrocarbon is an alkane, and the carbon number of the hydrocarbon is a positive integer greater than or equal to 10 and less than or equal to 16.

2. The use according to claim 1, characterized in that The pest control composition can be used to kill insects and / or non-insect organisms.

3. The use according to claim 1, characterized in that The hydrocarbon has an even number of carbon atoms.

4. The use according to claim 3, characterized in that The hydrocarbon is selected from the group consisting of n-decane, n-dodecane, n-tetradecane and n-hexadecane.

5. The use according to claim 4, characterized in that The isomer of the hydrocarbon compound is selected from the group consisting of isodecane, isododecane, isotetradecane and isohexadecane.

6. The use according to claim 1, characterized in that The formulation of the pest control composition is a fumigant, a spray or a solution.

7. The use according to claim 7, characterized in that When the formulation of the pest control composition is a fumigant, the dosage of the pest control composition is to use a concentration of not less than 5 mg of hydrocarbons and / or isomers thereof for fumigation in a space of one liter.

8. A method for pest control, comprising providing a pest control composition or its vapor into a space, characterized in that: The pest control composition contains at least one effective amount of active ingredient, and the active ingredient is an alkane with a carbon number of 10, 12, 14 or 16 or an isomer thereof.

9. The method for pest control according to claim 8, characterized in that: The active compound is n-decane, n-dodecane, n-tetradecane, n-hexadecane or an isomer of any of the foregoing compounds.

10. The method for pest control according to claim 8, characterized in that: When the pest control composition is not a fumigant, the effective amount of the active ingredient is at least 2.5 mg in a space of one liter.

11. The method for pest control according to claim 8, characterized in that: When the pest control composition is a fumigant, the effective amount of the active ingredient is at least 5 mg in a space of one liter.

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