Valve Repair System

Abstract

This invention discloses a valve repair system, including a valve repair device and a delivery device. The valve repair device includes at least one pair of clamping portions and at least one pair of elastic clamping portions. In its natural state, the pair of clamping portions are far apart from each other and respectively abut against the clamping portions opposite to them. The delivery device includes at least a pushing component, which includes a pushing catheter. The valve repair device is detachably connected to the distal end of the pushing catheter. The pushing catheter has multiple channels extending through its proximal and distal ends, and at least two opposing channels are included among the multiple channels, which are axially opposite to the two clamping portions. The valve repair system also includes at least two adjusting wires for controlling the angle at which the pair of clamping portions approach each other. Each adjusting wire is movably connected to the clamping portion and then folded in half to form two strands. The proximal ends of both strands can be movably inserted into the channels and connected to the proximal end of the pushing component. The two strands of each adjusting wire do not simultaneously insert into an opposing channel on the opposite side.

Description

Technical Field

[0001] This invention relates to the field of interventional medical device technology, and in particular to a valve repair system. Background Technology

[0002] Mitral valve disease is a common condition among the elderly, including two common types: mitral regurgitation and mitral stenosis, with mitral regurgitation being the most prevalent. Statistics show that the incidence of mitral regurgitation in people over 75 years of age is as high as 10%. Mild mitral regurgitation generally does not affect daily life, while moderate to severe mitral regurgitation requires intervention. Traditional surgical treatment involves open-heart surgery, where the heart is opened under cardiopulmonary bypass to repair or replace the valve. However, high-risk patients cannot tolerate this procedure. In recent years, interventional therapy has brought hope to high-risk patients with mitral regurgitation. Interventional therapy typically involves delivering instruments to the lesion site via catheter to repair or replace the valve. Abbott MitraClip and Edwards PASCAL are typical examples of interventional treatments. MitraClip was introduced into clinical use earlier. Its mechanical working principle is a four-bar linkage. The clamp is inserted via femoral vein puncture through the interatrial septum and advanced from the atrium to the vicinity of the mitral valve. It clamps and fixes the free edges of the anterior and posterior leaflets, creating a double-hole clamp on the mitral valve to ensure good leaflet alignment at end-systole and reduce regurgitation. Edwards PASCAL has a completely different mechanical working principle from MitraClip. Its design resembles a diamond-shaped folding clamp opening and closing mechanism. PASCAL's leaflet grasping force and leaflet fixation force are both based on the elastic recoil force of a pre-shaped metal. It also involves femoral vein puncture, interatrial septal puncture through a catheter, and clamping the mitral valve into a double-hole clamp.

[0003] Both PASCAL and MitraClip employ a structure using two drawstrings to control a pair of internal elastic clamping arms, facilitating tissue transport and clamping. The existing drawstring threading methods include... Figure 1 As shown, the existing scheme uses a single double-stranded 30' suture threaded through a pair of side holes 21'. While this scheme can utilize the traction clamp to compress the spacer in the middle to a smaller width, thus avoiding problems such as high delivery resistance or difficulty in retrieval, it has several drawbacks: First, the two sutures together are prone to tangling, increasing suture removal resistance or making normal suture removal impossible; second, the angle formed by the two sutures at the contact point with the clamp arm ring is small, resulting in a large shearing force between the sutures and the clamp arm ring during suture removal after surgery, causing significant damage to the sutures and posing a risk of failure; third, the clamp arm movement is greatly affected by the frictional resistance between the sutures and the edge of the holes, and this friction can also cause some damage to the sutures. These drawbacks lead to significant safety hazards and potential risks in the valve repair system. Summary of the Invention

[0004] Based on this, the present invention provides a valve repair system, which aims to improve the safety of valve repair systems.

[0005] To achieve this objective, the present invention adopts the following technical solution:

[0006] This invention provides a valve repair system, including a valve repair device and a delivery device for delivering the valve repair device to a preset position; wherein,

[0007] The valve repair device includes: at least one pair of clamping portions and at least one pair of elastic clamping portions; the pair of clamping portions is movable between an open position and a closed position, and the pair of clamping portions is located between the pair of clamping portions and is respectively opposite to the pair of clamping portions; in the natural state, the pair of clamping portions are far apart from each other and respectively fit against the clamping portions opposite to them.

[0008] The delivery device includes at least a pushing component, the pushing component includes a pushing catheter, the valve repair device is detachably connected to the distal end of the pushing catheter, the pushing catheter is provided with a channel penetrating its proximal and distal ends, the pushing catheter is provided with a plurality of channels in the circumferential direction of the pushing catheter, wherein at least two opposing channels are respectively axially opposite to the two clamping parts;

[0009] The valve repair system further includes at least two adjustment lines for controlling the angle at which a pair of clamping parts approach each other. Each adjustment line is movably connected to one of the clamping parts. After being movably connected to the clamping part, the adjustment line is folded in half to form two strands. The proximal ends of both strands can be movably inserted into the channel and connected to the proximal end of the push assembly. The two strands of each adjustment line are not simultaneously inserted into a corresponding channel on the opposite side.

[0010] In one embodiment, the plurality of channels further includes at least an intermediate channel located between two of the opposing channels.

[0011] In one embodiment, the proximal end of one of the two strands of each adjustment line passes through the opposite channel, and the proximal end of the other strand passes through one of the intermediate channels; or, the proximal ends of the two strands of each adjustment line pass through the two intermediate channels respectively.

[0012] In one embodiment, the proximal ends of the two strands of each adjustment line are simultaneously threaded through one of the intermediate channels.

[0013] In one embodiment, the proximal ends of the two strands of each adjustment line are simultaneously threaded into the opposite channel.

[0014] In one embodiment, the valve repair system further includes a limiting member disposed on the proximal side of the valve repair device and / or the distal side of the delivery catheter, wherein the adjustment line movably passes through the limiting member axially, and the limiting member is used to locally form a radial constraint on the adjustment line.

[0015] In one embodiment, the valve repair device further includes a support rod and an elastic spacer disposed between a pair of clamping portions. The clamping portions are connected to the distal end of the support rod and can be opened and closed relative to the support rod. The spacer is sleeved on the support rod, and the proximal end of the support rod extends beyond the proximal end of the spacer and has a first connecting portion at its proximal end. The distal end of the push catheter has a second connecting portion. The first connecting portion and the second connecting portion are detachably connected. The limiting member is disposed on the outer wall of the first connecting portion and / or the second connecting portion.

[0016] In one embodiment, the limiting member includes a limiting ring sleeved on the outer wall of the first connecting portion and / or the second connecting portion, the limiting ring having a first through hole through which the adjusting line can pass, and / or a first gap through which the adjusting line can pass between the inner wall of the limiting ring and the outer wall of the first connecting portion and / or the second connecting portion; or,

[0017] The limiting member includes a plurality of limiting seats disposed on the outer wall of the first connecting part and / or the second connecting part. The limiting seat is provided with a second through hole through which the adjustment line can pass, and / or a second gap is provided between the inner wall of the limiting seat and the outer wall of the first connecting part and / or the second connecting part, through which the adjustment line can pass.

[0018] In one embodiment, there are multiple first or second through holes, and two strands of each adjustment wire pass through different first or second through holes.

[0019] In one embodiment, at least a partial diameter at the distal end of the first or second through hole is smaller than the diameter at the proximal end of the first or second through hole, such that a support traction point is formed on the outer side of the inner wall at the distal end of the first or second through hole.

[0020] The valve repair system of this invention employs a novel threading method for the adjustment wire, avoiding the potential risks associated with a single double-stranded wire passing through a single hole. Furthermore, the limiting component provides local radial constraint on the adjustment wire, applying a pulling force towards the central axis. This allows for rapid and effective compression of the spacer to a smaller width, avoiding problems such as high delivery resistance and difficult retrieval. Attached Figure Description

[0021] Figure 1This is a partial schematic diagram of the threading of the sutures in an existing valve repair system;

[0022] Figure 2 This is a partial schematic diagram of the valve repair system of the present invention;

[0023] Figure 3 This is a schematic diagram of the threading of an adjustment wire in the valve repair system of the present invention;

[0024] Figure 4(a) is a schematic diagram of another type of adjustment line threading for the valve repair system of the present invention;

[0025] Figure 4(b) is a schematic diagram of another type of adjustment line threading for the valve repair system of the present invention;

[0026] Figure 4(c) is a schematic diagram of another type of adjustment line threading for the valve repair system of the present invention;

[0027] Figure 4(d) is a schematic diagram of another type of adjustment line threading for the valve repair system of the present invention;

[0028] Figure 5 This is a schematic diagram of the threading of another type of adjustment line in the valve repair system of the present invention;

[0029] Figure 6 This is a schematic diagram of the threading of another type of adjustment line in the valve repair system of the present invention;

[0030] Figure 7 This is a schematic diagram showing the adjustment line of the valve repair system of the present invention passing through the limiting ring provided on the second connecting part;

[0031] Figure 8 This is a schematic diagram showing the adjustment line of the valve repair system of the present invention passing through the limiting ring provided on the first connecting part;

[0032] Figure 9 This is a schematic diagram showing the adjustment line of the valve repair system of the present invention passing through the limiting seat;

[0033] Figure 10 This is a schematic diagram showing that the limiting seat of the valve repair system of the present invention has multiple second through holes;

[0034] Figure 11 This is a partial cross-sectional schematic diagram of the valve repair system of the present invention when the adjustment line passes through an exemplary first through hole / second through hole. Detailed Implementation

[0035] To make the objectives, technical solutions, and advantages of this invention clearer, exemplary embodiments of this disclosure will now be described in more detail with reference to the accompanying drawings. While exemplary embodiments of this disclosure are shown in the drawings, it should be understood that this disclosure can be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided to enable a more thorough understanding of this disclosure and to fully convey the scope of this disclosure to those skilled in the art.

[0036] It should be understood that the terminology used herein is for the purpose of describing particular exemplary embodiments only and is not intended to be limiting. Unless the context clearly indicates otherwise, the singular forms “a,” “an,” and “described” as used herein may also include the plural forms. The terms “comprising,” “including,” “containing,” and “having” are inclusive and therefore indicate the presence of the stated features, steps, operations, elements, and / or components, but do not exclude the presence or addition of one or more other features, steps, operations, elements, components, and / or combinations thereof. The method steps, processes, and operations described herein are not construed as requiring them to be performed in a particular order described or illustrated unless the order of performance is explicitly indicated. It should also be understood that additional or alternative steps may be used.

[0037] Although terms such as first, second, third, etc., may be used in this document to describe multiple elements, components, regions, layers, and / or segments, these elements, components, regions, layers, and / or segments should not be limited by these terms. These terms may be used only to distinguish one element, component, region, layer, or segment from another. Unless the context clearly indicates otherwise, terms such as "first," "second," and other numerical terms used herein do not imply order or sequence. Therefore, the first element, component, region, layer, or segment discussed below may be referred to as the second element, component, region, layer, or segment without departing from the teachings of the exemplary embodiments.

[0038] For ease of description, spatial relative terms may be used in the text to describe the relationship of one element or feature relative to another element or feature, as shown in the figure. These relative terms include, for example, "inside," "outside," "middle," "outer," "below," "below," "above," "over," etc. Such spatial relative terms are intended to include different orientations of the device in use or operation, other than those depicted in the figure. For example, if the device in the figure is flipped, an element described as "below other elements or features" or "below other elements or features" would subsequently be oriented as "above other elements or features" or "above other elements or features." Therefore, the example term "below" can include both upper and lower orientations. The device may be otherwise oriented (rotated 90 degrees or in other directions), and the spatial relative descriptors used in the text will be interpreted accordingly.

[0039] Additionally, it should be noted that in this invention, the end of a medical device implanted in a human or animal body, or the delivery device for transporting the medical device, closer to the operator is defined as the "proximal end," and the end farther from the operator is defined as the "distal end." Based on this principle, the "proximal end" and "distal end" of any component of the medical device or delivery device are defined. "Axial direction" refers to the length direction of the medical device during transport, and "radial direction" refers to the direction of the medical device perpendicular to its "axial direction." Based on this principle, the "axial direction" and "radial direction" of any component of the medical device are defined.

[0040] Please refer to Figure 2 and Figure 3 As shown, the present invention provides an exemplary valve repair system 100, the valve repair system 100 including a valve repair device 10, a delivery device for delivering the valve repair device 10 to a preset position, and at least two adjusting lines 30 for controlling a pair of elastic clamping portions 12 of the valve repair device 10, the two adjusting lines 30 respectively pulling the two clamping portions 12 to control the angle at which the pair of clamping portions 12 approach each other.

[0041] Specifically, such as Figure 2 As shown, the valve repair device 10 includes at least one pair of clamping portions 11 and at least one pair of elastic clamping portions 12. The pair of clamping portions 11 and the pair of clamping portions 12 are symmetrically arranged relative to the axis of the valve repair device 10. The pair of clamping portions 11 can move between an open position and a closed position. The pair of clamping portions 12 are located between the pair of clamping portions 11 and are respectively opposite to the pair of clamping portions 11. In the natural state, that is, when no external force is applied, that is, when the adjustment line 30 does not pull the clamping portions 12, the pair of clamping portions 12 are pre-shaped to move away from each other and are respectively attached to the clamping portions 11 opposite to them. The leaflet tissue is clamped between the clamping portions 12 and the clamping portions 11.

[0042] Combination Figure 2 and Figure 3 As shown, the delivery device includes at least a pushing assembly 20, which includes a pushing catheter 21. The valve repair device 10 is detachably connected to the distal end of the pushing catheter 21. The pushing catheter 21 has a channel 22 penetrating its proximal and distal ends on its wall. Multiple channels 22 are provided, spaced apart circumferentially along the wall of the pushing catheter 21. At least two opposing channels 221 are included among the multiple channels 22, each axially opposite to one of the two clamping portions 12. It should be noted that "multiple" in this invention refers to two or more, and "axially opposite" in this invention refers to the area where the opposing channels 221 are located within the axial projection region of the clamping portion 12.

[0043] Each adjusting wire 30 is movably connected to a clamping part 12. This movable connection can be, for example, through a hole in the clamping part 12 or through a connector (e.g., a pull ring) on ​​the clamping part 12. After being movably connected to the clamping part 12, the adjusting wire 30 is folded in half to form two strands, for example... Figure 2 or Figure 3 The two strands shown are the first strand 31 and the second strand 32. The proximal ends of both strands 31 and 32 are movably inserted into the channel 22 and connected to the proximal end of the pushing component 20. When the adjusting line 30 is pulled at its proximal end, the clamping part 12 connected to the pulled adjusting line 30 moves towards the center. In this embodiment, the two strands of each adjusting line 30 (i.e., the first strand 31 and the second strand 32) are not simultaneously inserted into a single opposite channel 221. It should be noted that, as described in this invention, the two strands of each adjusting line 30 (i.e., the first strand 31 and the second strand 32) not simultaneously inserted into a single opposite channel 221 means... Figure 1 The scheme shown.

[0044] Furthermore, the plurality of channels 22 also includes at least an intermediate channel 222 located between two opposing channels 221. That is, the plurality of channels 22 includes opposing channels 221 and an intermediate channel 222 located between two opposing channels 221.

[0045] When an intermediate channel 222 is provided, in one embodiment, the proximal end of one of the two strands of each adjusting line 30 is inserted into the opposite channel 221 on the opposite side, and the proximal end of the other strand is inserted into one of the intermediate channels 222. For example... Figure 2 and Figure 3As shown, the proximal end of the first strand 31 of the two threads passes through the opposite channel 221, while the proximal end of the second strand 32 passes through one of the intermediate channels 222. It should be noted that when there are multiple intermediate channels 222, the other adjusting thread can selectively pass through one of them. This embodiment uses a single-strand, single-hole design on both the opposite and side sides. On the one hand, when the adjusting thread 30 is tightened, the clamping part 12 can compress the spacer 13 to a smaller width, avoiding problems of high transport resistance and difficult retrieval during transport and retrieval. On the other hand, the two adjusting threads are threaded through separate holes, preventing tangling. Simultaneously, the angle formed by the two adjusting threads at the contact point with the clamping part is increased, significantly reducing shear force during suture removal after surgery, resulting in no significant damage to the adjusting threads. Furthermore, single-thread, single-hole threading also reduces the amount of cavity space occupied, lowering the difficulty of sterilization; moreover, this design reduces the impact of frictional resistance and wear.

[0046] When intermediate channels 222 are provided, as another implementation, the proximal ends of the two strands of each adjusting line 30 are respectively threaded into the two intermediate channels 222. For example... Figures 4(a) to 4(d) As shown, the proximal end of the first strand 31 of the two threads passes through a central channel 222 on one side, while the proximal end of the second strand 32 passes through a central channel 222 on the opposite side. It should be noted that when multiple central channels 222 are provided, each adjusting thread can selectively pass through one of them. In this embodiment, the angle formed by the two adjusting threads at the contact point with the clamping part is increased, significantly reducing the shear force when the sutures are withdrawn after surgery, resulting in no significant damage to the adjusting threads; moreover, this design reduces the impact of frictional resistance and wear.

[0047] When an intermediate channel 222 is provided, as another implementation, the proximal ends of the two strands of each adjusting line 30 are simultaneously threaded into one of the intermediate channels 222. For example... Figure 5 As shown, the proximal ends of the first strand 31 and the second strand 32 of the two wires simultaneously pass through one of the intermediate channels 222. It should be noted that when there are multiple intermediate channels 222, the two adjusting wires can selectively pass through one of them. Preferably, to ensure the overall stability of the valve repair system 100, the intermediate channels 222 through which the two adjusting wires 30 pass are symmetrically arranged. In this embodiment, when the clamping part is released, the movement of the clamping part is less affected by the frictional resistance between the adjusting wire and the edge of the hole, resulting in reduced wear.

[0048] When multiple channels 22 include relative channels 221 or include relative channels 221 and an intermediate channel 222 located between two relative channels 221, the proximal ends of the two strands of each adjusting line 30 are simultaneously inserted into the relative channel 221 opposite to it. For example... Figure 6As shown, the proximal ends of the first strand 31 and the second strand 32 of the two wires are simultaneously inserted into the opposing channel 221. When the intermediate channel 222 is provided, it can reduce the overall weight of the valve repair system 100, which is beneficial to ensuring overall balance and stability, and can also serve as a backup pathway. In this embodiment, when the clamping part is released, the movement of the clamping part is less affected by the frictional resistance between the adjusting wire and the edge of the hole, resulting in less wear.

[0049] Reference Figures 7-9 To facilitate delivery and retrieval, based on any of the above embodiments, the valve repair system 100 of the present invention further includes a limiting member. The limiting member is disposed on the proximal side of the valve repair device 10 and / or the distal side of the push catheter 21. The adjusting line 30 movably passes through the limiting member axially, and the limiting member is used to locally form a radial constraint on the adjusting line 30. When the adjusting line 30 passing through the limiting member is tightened, the limiting member can provide a constraining force on the adjusting line 30 in the direction of the central axis, which can effectively and quickly bring the pair of clamping parts 12 closer to each other. When the valve repair device 10 includes an elastic spacer 13, the setting of the limiting member can quickly and effectively compress the spacer 13 to a smaller width, avoiding problems of high delivery resistance or difficult retrieval during delivery and retrieval. It should be noted that the setting of the limiting member can be applied to any of the foregoing embodiments to form a new solution with better results.

[0050] Continue to refer to Figure 2 and Figures 7-9 As shown, the valve repair device 10 also includes a support rod 14 and an elastic spacer 13 disposed between a pair of clamping portions 12. The clamping portion 11 is connected to the distal end of the support rod 14 and can be opened and closed relative to the support rod 14. The spacer 13 is sleeved on the support rod 14, and the proximal end of the support rod 14 extends out of the proximal end of the spacer 13 and is provided with a first connecting portion 141 at its proximal end. The distal end of the push catheter 21 is provided with a second connecting portion 211. The first connecting portion 141 and the second connecting portion 211 are detachably connected. A limiting member is provided on the outer wall of the first connecting portion 141 and / or the second connecting portion 211.

[0051] One method of setting the limiting component is as follows: See Figure 7 As shown, the limiting member includes a limiting ring 41 sleeved on the outer wall of the second connecting part 211. In order to allow the adjustment line 30 to pass through, the limiting ring 41 is provided with a first through hole 40a through which the adjustment line 30 can pass, and / or a first gap (not shown) is provided between the inner wall of the limiting ring 41 and the outer wall of the second connecting part 211 for the adjustment line 30 to pass through.

[0052] Or, see Figure 8As shown, the limiting member includes a limiting ring 41 sleeved on the outer wall of the first connecting part 141. In order to allow the adjustment line 30 to pass through, the limiting ring 41 is provided with a first through hole 40a through which the adjustment line 30 can pass, and / or a first gap (not shown) is provided between the inner wall of the limiting ring 41 and the outer wall of the first connecting part 141 for the adjustment line 30 to pass through.

[0053] Alternatively, the limiting member includes a limiting ring 41 on the outer wall of the first connecting part 141 and a limiting ring 41 sleeved on the outer wall of the second connecting part 211. In order to allow the adjusting line 30 to pass through, the limiting ring 41 is provided with a first through hole 40a through which the adjusting line 30 can pass, and / or a first gap (not shown) is provided between the inner wall of the limiting ring 41 and the outer wall of the first connecting part 141 and the second connecting part 211 for the adjusting line 30 to pass through.

[0054] It should be understood that in the above-mentioned setting of the limiting member including the limiting ring 41, only the first through hole 40a or the first gap may be provided for the adjustment line 30 to pass through, or both the first through hole 40a and the first gap may be provided for the adjustment line 30 to pass through.

[0055] As another way to set the limit component, see [link to relevant documentation]. Figure 9 As shown, the limiting member includes a plurality of limiting seats 42 disposed on the outer wall of the first connecting portion 141 and / or the second connecting portion 211. Each limiting seat 42 has a second through hole 40b through which an adjustment line 30 can pass, and / or a second gap (not shown) is provided between the inner wall of the limiting seat 42 and the outer wall of the first connecting portion 141 and / or the second connecting portion 211, through which the adjustment line 30 can pass. It should be noted that although attached... Figure 9 The limiting seat 42 is provided on the first connecting part 141, but it is not limited thereto. The limiting seat 42 can also be provided on the second connecting part 211 or simultaneously on the first connecting part 141 and the second connecting part 211.

[0056] To prevent the two strands of the single adjusting wire from tangling, multiple first through holes 40a or second through holes 40b are provided, spaced apart circumferentially. The two strands of each adjusting wire 30 pass through different first through holes 40a or second through holes 40b. For example... Figure 10 As shown, there are two second through holes 40b on the limiting seat 42, spaced apart in the circumferential direction. The first strand 31 and the second strand 32 of the single adjusting wire 30 pass through the two second through holes 40b respectively, thereby avoiding the two strands from getting tangled.

[0057] Furthermore, at least a partial diameter at the distal end of the first through-hole 40a or the second through-hole 40b is smaller than the diameter at the proximal end of the first through-hole 40a or the second through-hole 40b, such that a support traction point is formed on the outer side of the inner wall at the distal end of the first through-hole 40a or the second through-hole 40b. It should be noted that this outer side of the inner wall refers to the inner wall side of the first through-hole 40a or the second through-hole 40b away from the axis of the valve repair system, and not the outer side of the first connecting portion 141 and / or the second connecting portion 211. Figure 11 As shown, the diameter of the first through hole 40a or the second through hole 40b gradually increases from far to near, that is, as... Figure 11 As shown in the S direction, the first through-hole 40a or the second through-hole 40b is inclined relative to the inner wall of the valve repair system and to the axis of the valve repair system, and the diameter of the first through-hole 40a or the second through-hole 40b gradually increases, such as... Figure 11 As shown, the diameter of the first through hole 40a or the second through hole 40b gradually increases from W1 at the far end to W2. This arrangement allows an effective pulling point to be formed at the far end of the hole when the adjustment line 30 is pulled, so that the clamping part can quickly respond and retract, and the spacer 13 can be quickly compressed to a smaller width. At the same time, the large diameter at the near end facilitates the sliding of the adjustment line 30.

[0058] Preferably, in order to reduce damage to the adjustment line 30, the opening at the distal end of the first through hole 40a or the second through hole 40b is rounded, so that the distal edge opening is flared outward, which prevents damage and facilitates the passage and retraction of the adjustment line.

[0059] The valve repair system of this invention employs a novel threading method for the adjustment wire, avoiding the potential risks associated with a single double-stranded wire passing through a single hole. Furthermore, the limiting component provides local radial constraint on the adjustment wire, applying a pulling force towards the central axis. This allows for rapid and effective compression of the spacer to a smaller width, avoiding problems such as high delivery resistance and difficult retrieval.

[0060] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0061] The embodiments described above are merely illustrative of several implementations of the present invention, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the invention patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these all fall within the protection scope of the present invention. Therefore, the protection scope of this invention patent should be determined by the appended claims.

Claims

1. A valve repair system, characterized in that, It includes a valve repair device and a delivery device for delivering the valve repair device to a predetermined position; wherein, The valve repair device includes: at least one pair of clamping portions and at least one pair of elastic clamping portions; the pair of clamping portions is movable between an open position and a closed position, and the pair of clamping portions is located between the pair of clamping portions and is respectively opposite to the pair of clamping portions; in the natural state, the pair of clamping portions are far apart from each other and respectively fit against the clamping portions opposite to them. The delivery device includes at least a pushing component, the pushing component includes a pushing catheter, the valve repair device is detachably connected to the distal end of the pushing catheter, the pushing catheter is provided with a channel penetrating its proximal and distal ends, the pushing catheter is provided with a plurality of channels in the circumferential direction of the pushing catheter, wherein at least two opposing channels are respectively axially opposite to the two clamping parts, the opposing channels are located in the region of the axial projection of the clamping parts; The valve repair system further includes at least two adjustment lines for controlling the angle at which a pair of clamping parts approach each other. Each adjustment line is movably connected to one of the clamping parts. After being movably connected to the clamping part, the adjustment line is folded in half to form two strands. The proximal ends of both strands can be movably inserted into the channel and connected to the proximal end of the push assembly. The two strands of each adjustment line are not simultaneously inserted into a corresponding channel on the opposite side. The plurality of channels also includes at least one intermediate channel located between two of the opposing channels, and at least one of the two strands of each adjustment line has its proximal end passing through one of the intermediate channels.

2. The valve repair system of claim 1, wherein, The proximal end of one of the two strands of each adjustment line is inserted into the opposite channel on the opposite side, and the proximal end of the other strand is inserted into one of the intermediate channels.

3. The valve repair system of claim 1, wherein, The two strands of each adjustment line are respectively threaded through the two intermediate channels at their proximal ends. Alternatively, the proximal ends of the two strands of each of the adjustment lines are simultaneously threaded through one of the intermediate channels.

4. The valve repair system of any of claims 1-3, wherein, The valve repair system also includes a limiting member located on the proximal side of the valve repair device and / or the distal side of the push catheter. The adjustment line axially passes through the limiting member, and the limiting member is used to locally form a radial constraint on the adjustment line.

5. The valve repair system of claim 4, wherein, The valve repair device further includes a support rod and an elastic spacer disposed between a pair of clamping portions. The clamping portion is connected to the distal end of the support rod and can be opened and closed relative to the support rod. The spacer is sleeved on the support rod, and the proximal end of the support rod extends beyond the proximal end of the spacer and has a first connecting portion at its proximal end. The distal end of the push catheter has a second connecting portion. The first connecting portion and the second connecting portion are detachably connected. The limiting member is disposed on the outer wall of the first connecting portion and / or the second connecting portion.

6. The valve repair system of Ciaim 5, wherein, The limiting member includes a limiting ring sleeved on the outer wall of the first connecting portion and / or the second connecting portion, the limiting ring having a first through hole through which the adjusting line can pass, and / or a first gap through which the adjusting line can pass between the inner wall of the limiting ring and the outer wall of the first connecting portion and / or the second connecting portion; or, The limiting member includes a plurality of limiting seats disposed on the outer wall of the first connecting part and / or the second connecting part. The limiting seat is provided with a second through hole through which the adjustment line can pass, and / or a second gap is provided between the inner wall of the limiting seat and the outer wall of the first connecting part and / or the second connecting part, through which the adjustment line can pass.

7. The valve repair system according to claim 6, characterized in that, The first or second through hole is provided in multiple ways, and the two strands in each adjustment line pass through different first or second through holes respectively.

8. The valve repair system according to claim 6, characterized in that, At least a partial diameter at the distal end of the first or second through hole is smaller than the diameter at the proximal end of the first or second through hole, such that a support traction point is formed on the outer side of the inner wall at the distal end of the first or second through hole.

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