Blood analysis device

Abstract

The invention discloses blood analysis equipment which comprises a blood routine examination assembly and a specific protein detection assembly, the specific protein detection assembly comprises a cup body, and windows are formed in the two opposite side faces of the cup body respectively; the two light-transmitting pieces are respectively arranged at the two windows and seal the corresponding windows, the two light-transmitting pieces and the cup body are matched to form a containing cavity for containing reaction liquid, so that the light-transmitting pieces can be made of materials with good wear resistance and smudginess resistance, the light-transmitting performance of the light-transmitting pieces is still good even if the light-transmitting pieces are used for a long time, and the service life of the light-transmitting pieces is prolonged. And the accuracy of an analysis result is not influenced.

Description

Technical Field

[0001] The present invention relates to the technical field of blood analysis, and particularly to a blood analysis device. Background Art

[0002] There are many existing detection devices for blood analysis. For example, those with a separate design of a mixing pool and a detection pool, that is, the mixing of blood samples and reagents and the detection are realized in two separate pools, which results in a relatively complex structure of the detection device for blood analysis.

[0003] To overcome the deficiencies of the foregoing design, an integrally formed blood analysis reaction cup has emerged. To ensure the light transmittance of the reaction cup, the entire reaction cup can only be processed with a plastic material having good plasticity. However, the wear resistance and dirt resistance of the plastic material with good plasticity are poor. After long-term use, the light transmittance of the reaction cup will be affected, thereby affecting the accuracy of the analysis results.

[0004] In view of the above deficiencies, it is necessary to design a blood analysis device. Summary of the Invention

[0005] Therefore, the technical problem to be solved by the present invention is that in the prior art, an integrally formed reaction cup is processed with a plastic material having good plasticity, and its wear resistance and dirt resistance are poor, which will affect the accuracy of the analysis results after long-term use. Thus, a reaction cup is provided.

[0006] To solve the above technical problem, the technical solution of the present invention is as follows:

[0007] A blood analysis device, comprising:

[0008] A complete blood count detection component;

[0009] A specific protein detection component, comprising:

[0010] A cup body, on opposite sides of which windows are respectively opened;

[0011] Two light-transmitting members, respectively disposed at the two windows and sealing the corresponding windows, and the two light-transmitting members and the cup body cooperate to form a receiving cavity for receiving a reaction solution.

[0012] The technical solution of the present invention has the following advantages:

[0013] The blood analysis device provided by the present invention includes a complete blood count detection component and a specific protein detection component. The specific protein detection component includes a cup body and two light-transmitting members. Windows are respectively opened on the opposite side surfaces of the cup body. An open cup mouth is provided at the upper end of the cup body, and a discharge port is provided at the lower end of the cup body. The two light-transmitting members are respectively arranged at the windows and seal the corresponding windows. The two light-transmitting members and the cup body cooperate to form a reaction liquid accommodating cavity. In this way, the light-transmitting members can be made of materials with good wear resistance and dirt resistance. Even after long-term use, the light transmittance of the light-transmitting members will still be very good, which will not affect the entry and exit of the detection light, and thus ensure the accuracy of the analysis result.

[0014] A blood analysis device includes:

[0015] A complete blood count detection component;

[0016] A specific protein detection component, including:

[0017] A cup body, on the opposite side surfaces of which windows are respectively opened;

[0018] Two light-transmitting members, which are respectively arranged at the two windows and seal the corresponding windows. The two light-transmitting members and the cup body cooperate to form a reaction liquid accommodating cavity; wherein the materials of the cup body and the light-transmitting members are different.

[0019] Furthermore, two convex strips are provided on the opposite side walls of the cup body. The two convex strips are respectively located on both sides of one window. The light-transmitting member is fixed on the side wall between the two convex strips. Preferably, the light-transmitting member is fixedly bonded or heat-melted to the side wall.

[0020] The technical solution of the present invention has the following advantages:

[0021] 1. The blood analysis device provided by the present invention includes a complete blood count detection component and a specific protein detection component. The specific protein detection component includes a cup body and two light-transmitting members. Windows are respectively opened on the opposite side surfaces of the cup body. An open cup mouth is provided at the upper end of the cup body, and a discharge port is provided at the lower end of the cup body. The two light-transmitting members are respectively arranged at the two windows and seal the corresponding windows. The two light-transmitting members and the cup body cooperate to form a reaction liquid accommodating cavity. Among them, the materials of the cup body and the light-transmitting members are different. In this way, the light-transmitting members can be made of materials with good wear resistance and dirt resistance, while the cup body can be made of materials with lower cost and easier processing, so that the reaction cup can take into account both the processing cost and the processing convenience, and can also ensure that the light transmittance of the light-transmitting members is still good after long-term use, thereby ensuring the detection reliability of the blood analysis device after long-term use.

[0022] A blood analysis device includes:

[0023] A complete blood count detection component;

[0024] Specific protein detection component, comprising:

[0025] A cup body, on the opposite two side surfaces of which windows are respectively opened, an open cup mouth is provided at the upper end of the cup body, and a discharge port is provided at the lower end of the cup body;

[0026] Two light-transmitting members, which are respectively arranged at the two windows and seal the corresponding windows, and the two light-transmitting members and the cup body cooperate to form a containing cavity for containing a reaction solution.

[0027] Further, the cup body is in a trumpet-shaped structure that is larger at the top and smaller at the bottom.

[0028] Further, in the direction from the cup mouth to the discharge port, the cup body sequentially includes a filling section, a light inspection section, and a discharge section, and the two windows are opened on the opposite two side walls of the light inspection section.

[0029] Further, a reagent inlet communicating with the containing cavity is further provided on the side wall of the filling section.

[0030] Further, the discharge section includes a conical transition portion and a drain pipe connected to the transition portion.

[0031] Further, a liquid guiding structure is connected around the outer wall surface of the cup body, and a liquid guiding channel communicating with the outer wall surface of the cup body is formed on the liquid guiding structure, and the reaction solution overflowing from the cup mouth is adapted to be discharged outward through the liquid guiding channel.

[0032] Further, the liquid guiding structure includes:

[0033] A liquid guiding plate, which is in a flat plate shape and is connected around the outer wall surface of the cup body, the liquid guiding plate is located above the window and vertically blocks the window;

[0034] At least two baffle plates, which are connected to the liquid guiding plate and extend from the liquid guiding plate towards the cup mouth direction, and the liquid guiding groove formed by the enclosure of adjacent two baffle plates above the liquid guiding plate is the liquid guiding channel.

[0035] The technical solution of the present invention has the following advantages:

[0036] The blood analysis device provided by the present invention includes a blood routine detection component and a specific protein detection component. The specific protein detection component includes a cup body and two light-transmitting members. Windows are respectively opened on the opposite two side surfaces of the cup body. The two light-transmitting members are respectively arranged at the two windows and seal the corresponding windows. The two light-transmitting members and the cup body cooperate to form a containing cavity for containing a reaction solution. Among them, an open cup mouth is provided at the upper end of the cup body, so that it is convenient to add a blood sample. A discharge port is provided at the lower end of the cup body, so that after the detection, it is convenient to discharge the reaction solution. Description of the Drawings

[0037] In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings required for the description of the specific embodiments or the prior art. Obviously, the drawings in the following description are some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0038] Figure 1 Schematic three-dimensional structure diagram of the blood analysis device in the embodiment of the present invention;

[0039] Figure 2 Schematic three-dimensional diagram of the connection between the reaction cup and the fixing base in the embodiment of the present invention;

[0040] Figure 3 Schematic three-dimensional diagram of the cup body in the embodiment of the present invention;

[0041] Figure 4 Schematic three-dimensional diagram of the light-transmitting member in the embodiment of the present invention;

[0042] Figure 5 Schematic three-dimensional diagram of the combination of the cup body and the light-transmitting member in the embodiment of the present invention;

[0043] Figure 6 Schematic cross-sectional structure diagram of the reaction cup in the embodiment of the present invention.

[0044] Explanation of the reference numerals:

[0045] A, blood analysis device; A1, sampler; B, blood routine detection component; C, specific protein detection component; C0, reaction cup; C1, fixing base; C2, light source component; C3, pressing member; C4, light receiving and analyzing component; C5, side opening; C6, card slot; 1, cup body; 10, cup mouth; 11, filling section; 111, reagent inlet tube; 12, light detection section; 121, window; 13, discharge section; 131, transition part; 132, discharge tube; 14, discharge port; 2, light-transmitting member; 3, convex strip; 4, liquid guiding structure; 41, liquid guiding plate; 42, baffle; 43, reinforcing plate; 44, liquid guiding channel. Specific embodiments

[0046] The following will clearly and completely describe the technical solutions of the present invention with reference to the drawings. Obviously, the described embodiments are some embodiments of the present invention, rather than all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

[0047] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present invention. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0048] In the description of the present invention, it should be noted that unless otherwise clearly specified and limited, the terms "mounted", "connected", "coupled" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, an electrical connection; it can be directly connected, or indirectly connected through an intermediate medium, and it can be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific situations.

[0049] In addition, the technical features involved in different embodiments of the present invention described below can be combined with each other as long as they do not conflict with each other.

[0050] As Figures 1 to 6 shown, this embodiment provides a blood analysis device, including a complete blood count detection component and a specific protein detection component. Since the main improvement of the present invention lies in the specific protein detection component, the complete blood count detection component as the prior art will not be elaborated here.

[0051] The specific protein detection component includes a reaction cup C0, a fixed seat C1, a light source component C2, a light receiving and analyzing component C4, and a mixing device (not shown). Specifically, an installation cavity for placing the reaction cup C0 is provided inside the fixed seat C1. The lower end of the reaction cup C0 extends into the installation cavity. The opposite sides of the reaction cup C0 are respectively a light incident surface and a light exit surface. The light source component C2 is fixedly installed on the fixed seat C1 and faces the light incident surface of the reaction cup C0, and is used to emit detection light to the light incident surface of the reaction cup C0. The light receiving and analyzing component C4 is installed on the fixed seat C1 and faces the light exit surface of the reaction cup C0, and is used to receive the detection light emitted from the light exit surface of the reaction cup C0. The optical path channel formed by the detection light emitted by the light source component C2 passing through the reaction cup C0 and being received by the light receiving and analyzing component C4 is the optical detection channel. Side openings C5 are provided on both sides of the installation cavity.

[0052] The mixing device can improve the mixing uniformity of the blood sample and the reagent. During the mixing process of the blood sample and the reagent, the reaction solution (here the reaction solution refers to the liquid formed after the blood sample and the reagent are mixed and reacted) in the reaction cup C0 will surge.

[0053] The reaction cup C0 includes a cup body 1 and two light-transmitting members 2.

[0054] The cup body 1 is integrally formed of a plastic material. Of course, according to actual situations, a metal material can also be selected. The cup body 1 is wider at the top and narrower at the bottom. The upper end of the cup body 1 is provided with a cup mouth 10, and the lower end is provided with a discharge port 14. The reaction liquid can be emptied through the discharge port 14, and the mixing device can also inject bubbles into the reaction cup C0 through the discharge port 14 to form a turbulent flow in the reaction cup C0 to achieve the mixing of the reaction liquid. Of course, the bubbles finally overflow from the cup mouth 10 out of the reaction cup C0.

[0055] In the direction from the cup mouth 10 to the discharge port 14, the cup body 1 includes a filling section 11, an optical inspection section 12, and a discharge section 13 that are sequentially connected.

[0056] The filling section 11 is in a flared shape, and a reagent inlet is provided on the side wall. In this embodiment, a reagent inlet tube 111 is also provided corresponding to the reagent inlet, and the reagent inlet tube 111 is integrally formed with the cup body 1. Of course, the reagent inlet tube 111 can also be separately formed and then inserted and matched with the reagent inlet. The reagent is injected into the reaction cup C0 through the reagent inlet tube 111, and the reagent reacts with the blood sample to form a reaction liquid. The reagent inlet is provided on the side wall of the filling section 11 instead of on the side wall of the optical inspection section 12 in order to increase the distance between the reagent inlet and the optical inspection section 12, so as to prevent the surging reaction liquid from moving upward during the mixing process and then permeating with the reagent, thereby affecting the accuracy of the optical analysis result. The reagent inlet tube 111 is inclined downward toward the optical inspection section 12 to facilitate the reagent to smoothly enter the reaction cup C0.

[0057] The optical inspection section 12 is in the shape of a cuboid. Windows 121 are respectively opened on the light incident surface and the light exit surface of the optical inspection section 12, and each window 121 communicates with the reaction cup C0. In this embodiment, the reason for opening the two windows 121 on the light incident surface and the light exit surface of the optical inspection section 12 instead of expanding the windows 121 to the filling section 11 and the discharging section 13 is that, on the one hand, the usage area of the light transmissive member 2 can be correspondingly reduced, thereby improving the anti-collision performance of the reaction cup C0. Additionally, since the reaction liquid in the optical inspection section 12 is mixed and reacted sufficiently, the optical detection performed through the reaction liquid in the optical inspection section 12 results in a more accurate analysis result. On the two opposite side walls of the optical inspection section 12, two oppositely arranged convex strips 3 are provided. The two convex strips 3 are respectively located on both sides of a window 121, and the light transmissive member 2 is fixed on the side wall between the two convex strips 3. Preferably, the light transmissive member 2 is adhesively fixed or heat-melted and fixed to the side wall, and on both sides of each light transmissive member 2, it is adhesively or heat-melted and fixed to the two convex strips 3 respectively. The setting of the convex strips 3 can, on the one hand, increase the connection area between the light transmissive member 2 and the cup body 1, and on the other hand, protect the light transmissive member 2 from the side, preventing the light transmissive member 2 from falling off the cup body 1 due to lateral external force. In this embodiment, the two convex strips 3 are both in the shape of plates and are parallel to each other, and the two convex strips 3 are integrally formed with the cup body 1. Of course, the convex strips 3 can also be independently formed and then assembled on the cup body 1.

[0058] The discharging section 13 includes a transition portion 131 and a discharging pipe 132 connected to the bottom of the transition portion 131. The transition portion 131 is in a conical shape to facilitate the full discharge of the reaction liquid along the transition portion 131, the discharging pipe 132, and the discharge port 14, thereby reducing the influence of cross-contamination caused by residual reaction liquid on the accuracy of the optical analysis result. The discharging pipe 132 can be integrally formed with the cup body 1 or can be independently formed and then inserted and matched with the transition portion 131.

[0059] The two light transmissive members 2 are both flat and thin sheets, and are respectively arranged at the two windows 121 and seal the corresponding windows 121. The two light transmissive members 2 and the optical inspection section 12 cooperate to form a receiving cavity for the reaction liquid. The light transmissive member 2 is made of glass or quartz. The flat and thin sheet-shaped light transmissive member 2 can make the incident light enter the reaction cup C0 as parallel as possible.

[0060] A liquid guiding structure 4 is connected around the outer wall surface of the cup body 1, and the liquid guiding structure 4 is pressed by a pressing member C3 on the fixing seat C1. In this embodiment, the pressing member C3 is a screw, and the top cap of the screw is used to press the liquid guiding structure 4. In this way, the upper part of the reaction cup C0 can be better fixed, improving the stability of the reaction cup C0, and preventing the reaction liquid in the reaction cup C0 from spilling and the reaction liquid from shaking into the reagent inlet pipe 111, thereby causing the reagent to be contaminated. A liquid guiding channel 44 communicating with the outer wall surface of the cup body 1 is formed on the liquid guiding structure 4 (such as Figure 5As shown. The liquid guiding structure 4 is symmetrically arranged with respect to the cup body 1. The width of the liquid guiding structure 4 is greater than the maximum width of the cup body 1. In this way, the liquid guiding structure 4 can receive as much reaction liquid overflowing from the cup mouth 10 as possible and discharge it outward through the liquid guiding channel 44. In this embodiment, the liquid guiding structure 4 is integrally formed with the cup body 1, and the liquid guiding structure 4 includes a liquid guiding plate 41 and two baffle plates 42.

[0061] The liquid guiding plate 41 is in a flat plate shape and is connected around the outer wall surface of the cup body 1. The upper surface of the liquid guiding plate 41 is perpendicular to the axis of the cup body 1. In this embodiment, the liquid guiding structure 4 is located in the card slot C6, and the liquid guiding plate 41 abuts against the bottom surface of the card slot C6.

[0062] The two baffle plates 42 are connected to both sides of the liquid guiding plate 41 and extend in the direction of the cup mouth 10 from the liquid guiding plate 41. The liquid guiding groove formed by enclosing the two baffle plates 42 above the liquid guiding plate 41 is the liquid guiding channel 44. There is a notch (not marked) on one of the baffle plates 42, and the reagent inlet tube 111 is stuck in the notch, and the reagent inlet tube 111 enters the side opening C5. The liquid guiding structure 4 further includes three reinforcing plates 43. The bottom of each reinforcing plate 43 is connected to the liquid guiding plate 41. One of the reinforcing plates 43 is perpendicular to the baffle plate 42, one end is connected to the cup body 1, and the other end is connected to the baffle plate 42. The other two reinforcing plates 43 are parallel to the baffle plate 42, one end is a free end, and the other end is connected to the cup body 1. The setting of the reinforcing plates 43 can improve the strength of the liquid guiding structure 4. In addition, the number of the baffle plates 42 can also be three, four, or even more, which can be set according to actual needs and will not be specifically limited here.

[0063] Of course, the liquid guiding structure 4 can also be independently formed and then assembled on the cup body 1. And the liquid guiding structure 4 itself can be made in a split manner and then spliced into a whole. In this way, the difficulty of controlling the machining accuracy of the mounting holes on the liquid guiding plate 41 that cooperate with the cup body 1 can be reduced. The split liquid guiding plate 41 can be easily and tightly connected to the outer wall surface of the cup body 1 in an adhesive form, avoiding the occurrence of liquid leakage due to the machining accuracy error of the mounting holes on the liquid guiding plate 41, resulting in a fitting gap between the liquid guiding plate 41 and the outer wall surface of the cup body 1.

[0064] The working process of the optical analysis device is introduced below:

[0065] Place the reaction cup C0 on the fixing seat C1 and press it with the pressing member C3;

[0066] Add the blood sample into the reaction cup C0 from the cup mouth 10;

[0067] The blood sample is collected by the sampler A1 and then enters the reaction cup C0;

[0068] Reagents are added into the reaction cup C0 from the reagent inlet tube 111 and the reagent inlet. The reagents and the blood sample will be mixed and reacted in the accommodation cavity to form a reaction solution.

[0069] The light source assembly C2 emits detection light. The detection light enters the accommodation cavity through the window 121 on the light incident surface, forms scattered light after being scattered by the reaction solution, and the scattered light exits from the window 121 on the light exit surface. The scattered light is received and processed by the light receiving and analyzing assembly C4 to form an optical analysis result.

[0070] In this embodiment, the reaction cup C0 includes a cup body 1 and two light-transmitting members 2. Windows 121 are respectively formed on the opposite side surfaces of the cup body 1. The two light-transmitting members 2 are respectively arranged at the two windows 121 and seal the corresponding windows 121. The two light-transmitting members 2 and the cup body 1 cooperate to form an accommodation cavity for accommodating the reaction solution. The materials of the light-transmitting member 2 and the cup body 1 are different. In this way, the light-transmitting member 2 can be made of a material with good wear resistance and dirt resistance, while the cup body 1 can be made of a material with lower cost and easier processing, so that the reaction cup C0 can not only take into account the processing cost and processing convenience, but also ensure that the light-transmitting performance of the light-transmitting member is still good after long-term use, thereby ensuring the detection reliability of the blood analysis device after long-term use.

[0071] Obviously, the above embodiments are only examples given for clear illustration and are not limitations on the implementation manners. For those of ordinary skill in the art, other different forms of changes or variations can be made based on the above description. It is not necessary and impossible to list all the implementation manners here. And the obvious changes or variations derived therefrom are still within the protection scope of the present invention.

Claims

1. A blood analysis device, characterized in that: include: Blood routine test component (B); Specific protein detection kit (C), including: A cup body (1), wherein windows (121) are respectively provided on two opposite side surfaces of the cup body (1); Two light-transmitting members (2) are respectively arranged at the two windows (121) and seal the corresponding windows (121); the two light-transmitting members (2) and the cup body (1) cooperate to form a containing cavity for containing the reaction liquid.

2. A blood analysis device, characterized in that: include: Blood routine test component (B); Specific protein detection kit (C), including: A cup body (1), wherein windows (121) are respectively provided on two opposite side surfaces of the cup body (1); Two light-transmitting members (2) are respectively arranged at the two windows (121) and seal the corresponding windows (121); the two light-transmitting members (2) and the cup body (1) cooperate to form a containing cavity for containing the reaction liquid; wherein the cup body (1) and the light-transmitting member (2) are made of different materials.

3. The blood analysis device according to claim 2, characterized in that: Two convex strips (3) are provided on the two opposite side walls of the cup body (1), and the two convex strips (3) are respectively located on the two sides of a window (121), and the light-transmitting member (2) is fixed on the side wall between the two convex strips (3). Preferably, the light-transmitting member (2) is fixed to the side wall by bonding or hot-melt.

4. A blood analysis device, characterized in that: include: Blood routine test component (B); Specific protein detection kit (C), including: A cup body (1), wherein windows (121) are respectively provided on two opposite side surfaces of the cup body (1), an open cup mouth (10) is provided at the upper end of the cup body (1), and a discharge port (14) is provided at the lower end of the cup body (1); Two light-transmitting members (2) are respectively arranged at the two windows (121) and seal the corresponding windows (121); the two light-transmitting members (2) and the cup body (1) cooperate to form a containing cavity for containing the reaction liquid.

5. The blood analysis device according to claim 4, characterized in that: The cup body (1) has a structure that is larger at the top and smaller at the bottom.

6. The blood analysis device according to claim 5, characterized in that: In the direction from the cup mouth (10) to the discharge port (14), the cup body (1) comprises a filling section (11), a light inspection section (12) and a discharge section (13) in sequence, and the two windows (121) are arranged on two opposite side walls of the light inspection section (12).

7. The blood analysis device according to claim 6, characterized in that: The side wall of the filling section (11) is also provided with a reagent inlet which is in communication with the containing cavity.

8. The blood analysis device according to claim 6, characterized in that: The discharge section (13) comprises a tapered transition portion (131) and a discharge pipe (132) connected to the transition portion (131).

9. The blood analysis device according to claim 4, characterized in that: The outer wall surface of the cup body (1) is surrounded and connected with a liquid guide structure (4), and the liquid guide structure (4) is formed with a liquid guide channel (44) which is in communication with the outer wall surface of the cup body (1), so that the reaction liquid overflowing from the cup mouth (10) is suitable for being discharged outward through the liquid guide channel (44).

10. The blood analysis device according to claim 9, characterized in that: The liquid guiding structure (4) comprises: A liquid guide plate (41) is in the shape of a flat plate and is connected around the outer wall surface of the cup body (1); the liquid guide plate (41) is located above the window (121) and vertically blocks the window (121); At least two baffles (42) are connected to the liquid guide plate (41) and extend from the liquid guide plate (41) toward the cup mouth (10); a liquid guide groove formed by two adjacent baffles (42) above the liquid guide plate (41) is the liquid guide channel (44).

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