Preparation method and device of non-PVC multi-layer co-extrusion film for medicine packaging multi-chamber bag

Abstract

The invention discloses a preparation method and device of a non-PVC multi-layer co-extrusion film for a medicine packaging multi-chamber bag, and relates to the technical field of multi-chamber bag preparation. Comprising a base, a feeding mechanism is arranged on the base in a lifting mode, an extrusion mechanism is rotationally arranged below the feeding mechanism, the extrusion mechanism comprises an extrusion box rotationally installed on the base, and two sealing plates are installed on the extrusion box in a sliding mode and used for sealing the extrusion box; a reinforcing mechanism is arranged on the feeding mechanism; the extrusion mechanism is reinforced; a cooling mechanism, an adsorption mechanism, a winding mechanism and a cutting mechanism are sequentially arranged in the discharging direction. The winding mechanism is used for winding the wire material; according to the preparation method of the non-PVC multi-layer co-extruded film, in the whole manufacturing process, no additive or other substances are added, and meanwhile no impurities except for the product are generated in the manufacturing process; the preparation device provided by the invention can be convenient to maintain, and can be used for carrying out winding treatment on the material wire rod in an emergency situation.

Description

Technical Field

[0001] The invention relates to the technical field of multi-chamber bag preparation, and in particular to a method and device for preparing a non-PVC multi-layer co-extruded film for a multi-chamber bag for packaging medicines. Background Art

[0002] The multi-chamber bag in drug packaging is a special design for packaging drugs. It uses multiple independent compartments or bags to separate drugs into different small chambers through special packaging methods. The design of the multi-chamber bag can effectively separate different drug ingredients or dosage forms to prevent them from having adverse reactions or interactions during storage and transportation. In the preparation process of the existing multi-chamber bags, additives and other substances are generally added, and impurities other than the product are also generated during the manufacturing process. There are obvious defects in the preparation industry. The preparation method of the non-PVC multi-layer co-extrusion film proposed in the present invention does not add any additives and other substances during the entire manufacturing process, and the manufacturing process does not generate any impurities other than the product; in addition, the current preparation device does not propose perfect measures in terms of maintenance and emergency response. For example, if an extruder extrude wire materials, how to deal with the wire materials in an emergency will not lead to material waste; the present invention proposes a preparation device that is easy to maintain and can roll up the material wire in the face of an emergency. Summary of the invention

[0003] In response to the above technical problems, the preparation method of the non-PVC multi-layer co-extrusion film proposed in the present invention does not add any additives or the like during the entire manufacturing process, and the manufacturing process does not produce any impurities other than the product; the preparation device proposed in the present invention is easy to maintain, and in the face of an emergency, the material wire can be wound up.

[0004] The use scheme of the present invention is: a preparation device for non-PVC multi-layer co-extruded film for multi-chamber bags for pharmaceutical packaging, including a base, a feeding mechanism is arranged on the base for lifting, an extrusion mechanism is rotatably arranged below the feeding mechanism, the extrusion mechanism includes an extrusion box rotatably installed on the base, two sealing plates are slidably installed on the extrusion box for sealing the extrusion box; a reinforcement mechanism is arranged on the feeding mechanism; used for reinforcing the extrusion mechanism; a cooling mechanism, an adsorption mechanism, a winding mechanism and a cutting mechanism are arranged in sequence in the discharge direction; the winding mechanism is used for winding the wire material.

[0005] Furthermore, the feeding mechanism includes a guide rod 1, a screw rod 1 and a motor 1 arranged on both sides of the base, the motor 1 is used to drive the screw rod 1, a feeding cylinder is movably arranged on the guide rod 1 and the screw rod 1, and the feeding cylinder and the screw rod 1 form a spiral pair; a feeding interface is arranged at the bottom end of the feeding cylinder, and the feeding interface is connected to the sealing plate on the extrusion mechanism; the reinforcement mechanism is arranged on the feeding cylinder.

[0006] Further, the extrusion mechanism includes a flipping motor disposed on the base. The flipping motor is used to drive the extrusion box, and an extrusion part is provided at one end of the extrusion box. An extrusion shaft is rotatably installed inside the extrusion box, and a second motor is provided at the end of the extrusion box. The second motor is used to drive the extrusion shaft. A support oil cylinder is provided at the bottom of the base, and the support oil cylinder is used to support the extrusion box.

[0007] Further, fixing holes are formed in the sealing plate, and a feeding interface is formed in the sealing plate. The reinforcement mechanism is matched with the fixing holes for sealing and reinforcement.

[0008] Further, the reinforcement mechanism includes a bracket disposed on the feeding cylinder. An installation frame is provided on the bracket, a pushing electric cylinder is provided on the installation frame, a spring is provided on the telescopic rod of the pushing electric cylinder, and two reinforcement sliding rods are slidably installed on the installation frame. A pushing wheel is connected between the two reinforcement sliding rods. A fixing rod is provided on the reinforcement sliding rod, and the fixing rod is docked with the fixing hole. A pushing part is provided on the reinforcement sliding rod, and the pushing part is pushed by the spring.

[0009] Further, a third motor and a third lead screw are provided at the bottom of the extrusion box. A belt mechanism is provided on the output shaft of the third motor for driving the third lead screw. The third lead screw is fixedly screwed with the bottom of the sealing plate.

[0010] Further, a maintenance mechanism is provided on the base and below the extrusion box. The maintenance mechanism includes a moving motor and a moving belt disposed on the base. The moving motor is used to drive the moving belt. A maintenance sliding seat is slidably installed on the base, and the maintenance sliding seat is attached to the moving belt. A fourth motor and a fourth lead screw are provided on the maintenance sliding seat. The fourth motor is used to drive the fourth lead screw. A fourth sliding seat is slidably installed on the maintenance sliding seat, and the fourth sliding seat and the fourth lead screw form a screw pair. A control electric cylinder is provided on the fourth sliding seat, a maintenance motor is provided on the telescopic rod of the control electric cylinder, and a maintenance part is provided on the output shaft of the maintenance motor.

[0011] Further, the cooling mechanism includes a cooling water tank and a spraying box disposed on the base. A spraying control electric cylinder is provided on the spraying box, a spraying part is provided on the telescopic rod of the spraying control electric cylinder, and the spraying part is communicated with the cooling water tank. The adsorption mechanism includes a position electric cylinder disposed on the base. A position sliding seat is provided on the telescopic rod of the position electric cylinder. An adsorption cylinder and a rotating motor are provided on the position sliding seat. The rotating motor is used to drive the adsorption cylinder. An adsorption layer is attached to the surface of the adsorption cylinder for adsorbing and removing moisture on the wire material. The adsorption mechanism further includes a fifth motor and a fifth lead screw disposed on the base and above and below the adsorption cylinder. The fifth motor is used to drive the fifth lead screw. A fifth sliding seat is slidably installed on the base, and the fifth sliding seat and the fifth lead screw form a screw pair. A scraping electric cylinder is provided on the fifth sliding seat, and a scraping ring is provided on the telescopic rod of the scraping electric cylinder.

[0012] Further, the winding mechanism includes an air flow box, a winding motor and an emergency take-up reel on the base. The air flow box is communicated with one end of the emergency take-up reel. The winding motor is used to drive the emergency take-up reel. Through holes are arrayed on the emergency take-up reel, and the wire material passes through the through holes. Air holes are arranged on the inner circumference of the through holes, and each through hole is communicated with the air flow box through the air holes to adsorb and remove the moisture remaining on the wire material; the cutting mechanism includes a collection box and a granulation box arranged on the base. A granulation electric cylinder is arranged on the granulation box, and a granulation part is arranged on the telescopic rod of the granulation electric cylinder.

[0013] A preparation method for a non-PVC multi-layer co-extruded film for pharmaceutical packaging multi-chamber bags includes the following steps: Raw material mixing and granulation: I. Raw material mixing; II. Kneading and extruding by a twin-screw machine; III. Cooling and strand pelletizing; IV. Granulating and collecting materials; Blown film process: I. Vacuum feeding to a raw material extruder; II. Screw extrusion through a multi-layer die head; III. Film bubble blowing: passing through an air compressor, drying and filtering, and 0.01um terminal filtering; IV. Film bubble cooling: passing through RO water production, a low-temperature heat exchanger, and 0.22um ultrafiltration; V. Rotating traction by a chevron plate; VI. Deviation correction and winding.

[0014] For the non-PVC multi-layer co-extruded film prepared by the present invention, the raw materials are mixed in different proportions, extruded through high-temperature physical changes, cooled and shaped by purified water, and finally obtained as products after being cut into different specifications. During the whole manufacturing process, no additives and other substances are added, and no impurities other than products are generated. For the trimming process, the trimmed edge materials are collected and uniformly treated as waste.

[0015] The co-extruded infusion film is composed of an outer layer, a middle layer and an inner layer. Each layer has different functions, so the raw material composition, proportion and thickness of each layer are different. The formula raw materials of each layer need to be weighed and mixed separately according to the requirements of the formula, and then enter a twin-screw kneading and extrusion unit for kneading, homogenization and extrusion, and then enter water-cooled strand pelletizing to finally obtain the outer layer, middle layer and inner layer blown film raw materials of each layer.

[0016] The outer layer, middle layer and inner layer blown film raw materials are sent into three extruders through a vacuum feeding system. The three extruders respectively measure and plasticize the raw materials and then extrude them into the die head through the screws. When the polymer melt flows out of the die head, it is cooled and shaped through a cooling water ring after being expanded and stretched thinner, and then introduced into the chevron plate, and then vertically enters the rotating chevron plate, and is wound into a large film roll after being traction-corrected. The large film roll is cut into finished films of various specifications.

[0017] The mixing and granulation of the formula raw materials are produced in the control area. The raw materials are transported by vacuum suction through stainless steel pipes. The blown film is carried out in a Class C clean environment. The inflation of the film bubble uses Class A clean air. The cooling and shaping of the film bubble are carried out by using water produced by a two-stage reverse osmosis process, which is sterilized by an on-line ultraviolet lamp and cooled at a low temperature; the slitting of the large film roll is carried out under a Class C background, and the inner packaging of the finished product is carried out in a Class C environment.

[0018] For the co-extruded infusion film from the input of raw materials to the warehousing of products, it mainly includes three major processes: mixing and granulation, blown film forming, and slitting and packaging. During the manufacturing process, the purchased raw materials are mixed in different proportions, extruded through high-temperature physical changes, cooled and shaped by purified water, and finally obtained products after slitting into different specifications. During the whole manufacturing process, no additives and other substances are added, and no impurities other than products are generated. For the edge materials cut during the slitting process, we collect them and uniformly dispose of them as waste; after slitting and packaging, they are warehoused, and then UV printing is carried out on some of the already slit white films according to customer requirements.

[0019] The beneficial effects of the present invention compared with the prior art are as follows: (1) The extrusion box can be driven by the flipping motor to flip, so that the sealing plate faces the bottom of the base, and then the motor three works to drive the sealing plate to move and separate. The maintenance slide is driven to move by the moving belt. The motor four works, the lead screw four rotates, and the slide four moves. The control electric cylinder controls the position of the maintenance part. The maintenance motor drives the maintenance part to remove the residues on the extrusion shaft; the extrusion box is flipped so that the sealing plate faces above the base, and the sealing plate is driven to merge and close. The fixing rod is again engaged with the fixing hole to achieve reinforcement and sealing to continue working; (2) The scraping electric cylinder can be used to control the scraping ring to fit on the surface of the adsorption cylinder. The motor five works, the slide five moves, and the scraping ring scrapes the surface of the adsorption cylinder to remove the adsorbed moisture, which is convenient for subsequent continued use, replacing high-power drying measures such as hot air drying; (3) In case of an emergency, for example, a failure occurs in the subsequent pelletizing area, the extruded wire material can be wound up emergently, that is, the wire passes through the through hole on the emergency winding drum to achieve a limiting effect. The winding motor works, and the emergency winding drum rotates to wind up the wire to avoid stacking of the wire material after extrusion; the wire finally passes through the pelletizing box, and the pelletizing part is controlled by the pelletizing electric cylinder to carry out pelletizing treatment; (4) During the whole manufacturing process of the present invention, no additives and other substances are added, and no impurities other than products are generated. Description of the Drawings

[0020] Figure 1 It is a schematic diagram of the overall structure of the present invention.

[0021] Figure 2 It is a schematic diagram of the installation structure of the extrusion box of the present invention.

[0022] Figure 3 Schematic diagram of the internal installation structure of the extrusion box of the present invention.

[0023] Figure 4 Schematic diagram of the sealing plate structure of the present invention.

[0024] Figure 5 Schematic diagram of the installation structure of the maintenance sliding seat of the present invention.

[0025] Figure 6 Schematic diagram of the installation structure of the reinforcement mechanism of the present invention.

[0026] Figure 7 Schematic diagram of the cooling mechanism structure of the present invention.

[0027] Figure 8 Schematic diagram of the adsorption mechanism structure of the present invention.

[0028] Figure 9 Schematic diagram of the installation structure of the adsorption cylinder of the present invention.

[0029] Figure 10 Schematic diagram of the installation structure of the emergency winding drum of the present invention.

[0030] Figure 11 Schematic diagram of the cutting mechanism structure of the present invention.

[0031] Figure 12 Process flow chart of the present invention.

[0032] Reference numerals: 1 - base; 2 - tilting motor; 3 - feeding cylinder; 4 - first guide rod; 5 - first lead screw; 6 - first motor; 7 - bracket; 8 - extrusion box; 9 - extrusion part; 10 - mounting frame; 11 - pushing electric cylinder; 12 - sealing plate; 1201 - fixing hole; 13 - second motor; 14 - support oil cylinder; 15 - moving belt; 16 - moving motor; 17 - extrusion shaft; 18 - third motor; 19 - third lead screw; 20 - maintenance sliding seat; 21 - fourth motor; 22 - fourth lead screw; 23 - fourth sliding seat; 24 - control electric cylinder; 25 - maintenance motor; 26 - maintenance part; 27 - reinforcement sliding rod; 28 - fixing rod; 29 - pushing part; 30 - spring; 31 - pushing wheel; 32 - cooling water tank; 33 - spraying box; 34 - spraying control electric cylinder; 35 - spraying part; 36 - position electric cylinder; 37 - fifth motor; 38 - fifth lead screw; 39 - fifth sliding seat; 40 - scraping electric cylinder; 41 - scraping ring; 42 - adsorption cylinder; 43 - position sliding seat; 44 - rotating motor; 45 - air flow box; 46 - winding motor; 47 - emergency winding drum; 48 - collection box; 49 - pelletizing box; 50 - pelletizing electric cylinder; 51 - pelletizing part. Detailed implementation manners

[0033] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings required for the description of the specific embodiments or the prior art. Obviously, the drawings in the following description are some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0034] Example: As Figures 1 to 12 shown, a preparation device for a non-PVC multi-layer co-extruded film for pharmaceutical packaging multi-chamber bags includes a base 1. A feeding mechanism is arranged on the base 1 in a lifting manner. Below the feeding mechanism, an extrusion mechanism is rotatably arranged. The extrusion mechanism includes an extrusion box 8 rotatably installed on the base 1. Two sealing plates 12 are slidably installed on the extrusion box 8 for sealing the extrusion box 8. A reinforcement mechanism is arranged on the feeding mechanism for reinforcing the extrusion mechanism. In the discharging direction, a cooling mechanism, an adsorption mechanism, a winding mechanism, and a cutting mechanism are sequentially arranged. The winding mechanism is used for winding wire materials.

[0035] The feeding mechanism includes guide rods 1 4, lead screws 1 5, and a motor 1 6 arranged on both sides of the base 1. The motor 1 6 is used to drive the lead screw 1 5. A feeding cylinder 3 is movably arranged on the guide rod 1 4 and the lead screw 1 5. The feeding cylinder 3 and the lead screw 1 5 form a screw pair. A feeding interface is arranged at the bottom end of the feeding cylinder 3, and the feeding interface is docked with the sealing plate 12 on the extrusion mechanism. The reinforcement mechanism is arranged on the feeding cylinder 3. The extrusion mechanism includes a flipping motor 2 arranged on the base 1. The flipping motor 2 is used to drive the extrusion box 8. An extrusion part 9 is arranged at one end of the extrusion box 8. An extrusion shaft 17 is rotatably installed inside the extrusion box 8, and a motor 2 13 is arranged at the end of the extrusion box 8. The motor 2 13 is used to drive the extrusion shaft 17. A support oil cylinder 14 is arranged at the bottom of the base 1. The support oil cylinder 14 is used to support the extrusion box 8.

[0036] Fixing holes 1201 are opened on the sealing plate 12, and a feeding interface is opened on the sealing plate 12. The reinforcement mechanism cooperates with the fixing holes 1201 for sealing and reinforcement. The reinforcement mechanism includes a bracket 7 arranged on the feeding cylinder 3. An installation frame 10 is arranged on the bracket 7. A pushing electric cylinder 11 is arranged on the installation frame 10. A spring 30 is arranged on the telescopic rod of the pushing electric cylinder 11. Two reinforcement sliding rods 27 are slidably installed on the installation frame 10. A pushing wheel 31 is connected between the two reinforcement sliding rods 27. A fixing rod 28 is arranged on the reinforcement sliding rod 27. The fixing rod 28 is docked with the fixing hole 1201. A pushing part 29 is arranged on the reinforcement sliding rod 27, and the pushing part 29 is pushed by the spring 30.

[0037] At the bottom of the extrusion box 8, there is a motor three 18 and a lead screw three 19. A belt mechanism is arranged on the output shaft of the motor three 18 for driving the lead screw three 19. The lead screw three 19 is fixedly connected with the bottom of the sealing plate 12 by a screw pair. On the base 1 and below the extrusion box 8, there is a maintenance mechanism. The maintenance mechanism includes a moving motor 16 and a moving belt 15 arranged on the base 1. The moving motor 16 is used for driving the moving belt 15. A maintenance sliding seat 20 is slidably mounted on the base 1. The maintenance sliding seat 20 is attached to the moving belt 15. On the maintenance sliding seat 20, there is a motor four 21 and a lead screw four 22. The motor four 21 is used for driving the lead screw four 22. A sliding seat four 23 is slidably mounted on the maintenance sliding seat 20. The sliding seat four 23 and the lead screw four 22 form a screw pair. On the sliding seat four 23, there is a control electric cylinder 24. On the telescopic rod of the control electric cylinder 24, there is a maintenance motor 25. On the output shaft of the maintenance motor 25, there is a maintenance part 26.

[0038] The cooling mechanism includes a cooling water tank 32 and a spraying box 33 arranged on the base 1. A spraying control electric cylinder 34 is arranged on the spraying box 33. On the telescopic rod of the spraying control electric cylinder 34, there is a spraying part 35. The spraying part 35 is communicated with the cooling water tank 32. The adsorption mechanism includes a position electric cylinder 36 arranged on the base 1. On the telescopic rod of the position electric cylinder 36, there is a position sliding seat 43. On the position sliding seat 43, there is an adsorption cylinder 42 and a rotating motor 44. The rotating motor 44 is used for driving the adsorption cylinder 42. An adsorption layer is attached to the surface of the adsorption cylinder 42 for adsorbing and removing moisture on the wire material. The adsorption mechanism further includes a motor five 37 and a lead screw five 38 arranged on the base 1 and above and below the adsorption cylinder 42. The motor five 37 is used for driving the lead screw five 38. A sliding seat five 39 is slidably mounted on the base 1. The sliding seat five 39 and the lead screw five 38 form a screw pair. And on the sliding seat five 39, there is a scraping electric cylinder 40. On the telescopic rod of the scraping electric cylinder 40, there is a scraping ring 41.

[0039] The winding mechanism includes an air flow box 45, a winding motor 46 and an emergency winding drum 47 on the base 1. The air flow box 45 is communicated with one end of the emergency winding drum 47. The winding motor 46 is used for driving the emergency winding drum 47. Through holes are arrayed on the emergency winding drum 47. The wire material passes through the through holes. Air holes are arranged on the inner circumference of the through holes. Each through hole is communicated with the air flow box 45 through the air hole to adsorb and remove moisture remaining on the wire material. The cutting mechanism includes a collection box 48 and a granulating box 49 arranged on the base 1. A granulating electric cylinder 50 is arranged on the granulating box 49. On the telescopic rod of the granulating electric cylinder 50, there is a granulating part 51.

[0040] A preparation method for a non-PVC multi-layer co-extruded film for pharmaceutical packaging multi-chamber bags includes the following steps: Raw material mixing and granulation: I. Raw material mixing; II. Kneading and extruding by a twin-screw machine; 3. Cooling the strips; 4. Pelletizing and collecting materials; Film blowing process: 1. Vacuum suction to the raw material extruder; 2. Screw extrusion multi-layer die head; 3. Membrane bubble inflation: through air compressor, dry filtration, 0.01um end filtration; 4. Membrane bubble cooling: through RO water production, low temperature heat exchanger, 0.22um ultrafiltration; 5. Rotational traction with herringbone splint; 6. Correction and rolling.

[0041] The working principle is as follows: the material is put into the feeding barrel 3 for mixing, the motor 6 works, the screw 5 rotates, the feeding barrel 3 moves, the feeding interface at the bottom of the feeding barrel 3 is docked with the feeding interface on the sealing plate 12, and the fixing rod 28 on the reinforcement slide bar 27 is docked with the fixing hole 1201, and the spring 30 is controlled to move by pushing the electric cylinder 11, and the spring 30 pushes the pushing part 29, that is, the reinforcement slide bar 27 moves to squeeze and seal the sealing plate 12; it should be noted that when the extrusion box 8 is subsequently maintained, the extrusion box 8 can be turned over by the turning motor 2 to make The sealing plate 12 faces the bottom of the base 1, and then the motor three 18 works to drive the sealing plate 12 to move and separate, and the maintenance slide 20 is driven to move by the moving belt 15, the motor four 21 works, the screw four 22 rotates, the slide four 23 moves, and the electric cylinder 24 controls the position of the maintenance part 26. The maintenance motor 25 drives the maintenance part 26 to remove the residue on the extrusion shaft 17; the extrusion box 8 is controlled to flip so that the sealing plate 12 faces the top of the base 1, and the sealing plate 12 is driven to merge and close, and the fixing rod 28 cooperates with the fixing hole 1201 again to achieve reinforced sealing to continue working.

[0042] The material enters the extrusion box 8 for transmission, that is, the extrusion shaft 17 is driven by the motor 2 13, and the wire material is extruded from the extrusion part 9. When passing through the spray box 33, the position of the spray part 35 is controlled by the spray control electric cylinder 34, and cooling water is sprayed through the spray part 35 to cool the wire material. Furthermore, the wire material passes between two adsorption cylinders 42, and the position of the adsorption cylinder 42 can be controlled by the position electric cylinder 36. The moisture on the surface of the wire material can be adsorbed and removed by the adsorption cylinder 42. Subsequently, the scraping ring 41 can be controlled by the scraping electric cylinder 40 to fit on the surface of the adsorption cylinder 42. The motor 5 37 works, the slide 5 39 moves, and the scraping ring 41 scrapes the surface of the adsorption cylinder 42 to remove the adsorbed moisture for subsequent continued use.

[0043] The wire material passes through the through-hole on the emergency winding drum 47 and works through the air box 45. Residual moisture can be transmitted through the air holes inside the through-hole to achieve the drying purpose. Further, in case of an emergency, for example, a failure occurs in the pelletizing area at the rear end, the extruded wire material can be wound emergently. That is, the wire passes through the through-hole on the emergency winding drum 47 to achieve the limiting effect. The winding motor 46 works, and the emergency winding drum 47 rotates to wind the wire to prevent the wire material from piling up after extrusion. Finally, the wire passes through the pelletizing box 49, and the pelletizing part 51 is controlled by the pelletizing electric cylinder 50 to perform pelletizing treatment.

[0044] In the subsequent film blowing process, the material particles are extruded through the raw material extruder and the screw extrudes through the multi-layer die head, and then through processes such as film bubble inflation, film bubble cooling, herringbone board rotation traction, and deviation rectification winding to complete the preparation. It should be noted that for the non-PVC multi-layer co-extruded film prepared in this embodiment, the raw materials are mixed in different proportions, extruded through high-temperature physical changes, cooled and shaped by purified water, and finally obtained the product after being slit into different specifications. During the whole manufacturing process, no additives or other substances are added, and no impurities other than the product are generated during the manufacturing process. For the slitting process, the edge materials cut off are collected and uniformly treated as waste.

[0045] The co-extruded infusion film is composed of an outer layer, a middle layer, and an inner layer. Each layer has different functions, so the raw material composition, proportion, and thickness of each layer are different. The formula raw materials of each layer need to be weighed and mixed separately according to the requirements of the formula, and then enter the twin-screw mixing and extrusion unit for mixing, homogenization, and extrusion, and then enter the water-cooled strand pelletizing to finally obtain the blown film raw materials for the outer layer, middle layer, and inner layer respectively.

[0046] The blown film raw materials for the outer layer, middle layer, and inner layer are sent into three extruders through the vacuum feeding system. The three extruders respectively meter and plasticize the raw materials and then extrude them into the die head through the screw. When the polymer melt flows out of the die head, it is cooled and shaped through the cooling water ring after being expanded and stretched thinner, and then introduced into the herringbone board, and then vertically enters the rotating herringbone board, and is wound into a large film roll after traction and deviation rectification. The large film roll is slit into finished films of various specifications.

[0047] The mixing and pelletizing of the formula raw materials are produced in the control area. The raw materials are transported by vacuum suction through stainless steel pipes. The film blowing is carried out in a Class C clean environment. The inflation of the film bubble uses Class A clean air. The cooling and shaping of the film bubble is carried out by using water produced by a two-stage reverse osmosis process, which is sterilized by an online ultraviolet lamp and cooled at a low temperature for water cooling. The slitting of the large film roll is carried out under a Class C background, and the inner packaging of the finished product is carried out in a Class C environment.

[0048] The co-extruded infusion film, from the input of raw materials to the warehousing of products, mainly includes three major processes: mixing and granulation, blown film forming, and slitting and packaging. During the manufacturing process, the purchased raw materials are mixed in different proportions, extruded through high-temperature physical changes, cooled and shaped with purified water, and finally obtained products after slitting into different specifications. During the whole manufacturing process, no additives or other substances are added, and no impurities other than products are generated. For the slitting process, the edge materials cut off during slitting are collected and uniformly treated as waste. After slitting, they are packaged and warehoused, and then UV printing is carried out on some of the already slit white films according to customer requirements.

Claims

1. A device for preparing a non-PVC multi-layer co-extruded film for a multi-chamber bag for pharmaceutical packaging, comprising a base (1), characterized in that: A feeding mechanism is provided on the base (1) in a lifting manner, and an extrusion mechanism is rotatably provided below the feeding mechanism. The extrusion mechanism comprises an extrusion box (8) rotatably mounted on the base (1), and two sealing plates (12) are slidably mounted on the extrusion box (8) for sealing the extrusion box (8); a reinforcement mechanism is provided on the feeding mechanism for reinforcing the extrusion mechanism; a cooling mechanism, an adsorption mechanism, a winding mechanism and a cutting mechanism are sequentially provided in the discharge direction; and the winding mechanism is used to perform winding processing on the wire material.

2. The device for preparing a non-PVC multi-layer co-extruded film for a multi-chamber bag for pharmaceutical packaging according to claim 1, characterized in that: The feeding mechanism comprises a guide rod (4), a screw rod (5) and a motor (6) arranged on both sides of the base (1); the motor (6) is used to drive the screw rod (5); a feeding cylinder (3) is movably arranged on the guide rod (4) and the screw rod (5); the feeding cylinder (3) and the screw rod (5) form a spiral pair; a feeding interface is arranged at the bottom end of the feeding cylinder (3), and the feeding interface is connected to a sealing plate (12) on the extrusion mechanism; and a reinforcement mechanism is arranged on the feeding cylinder (3).

3. The device for preparing a non-PVC multi-layer co-extruded film for a multi-chamber bag for pharmaceutical packaging according to claim 2, characterized in that: The extrusion mechanism comprises a flip motor (2) arranged on a base (1), the flip motor (2) being used to drive an extrusion box (8), one end of the extrusion box (8) being provided with an extrusion portion (9); an extrusion shaft (17) being rotatably mounted inside the extrusion box (8), and a second motor (13) being provided at the end of the extrusion box (8), the second motor (13) being used to drive the extrusion shaft (17); and a supporting oil cylinder (14) being provided at the bottom of the base (1), the supporting oil cylinder (14) being used to support the extrusion box (8).

4. The device for preparing a non-PVC multi-layer co-extruded film for a multi-chamber bag for pharmaceutical packaging according to claim 2, characterized in that: The sealing plate (12) is provided with a fixing hole (1201), and the sealing plate (12) is provided with a feed interface, and the reinforcement mechanism cooperates with the fixing hole (1201) to perform sealing reinforcement.

5. The device for preparing a non-PVC multi-layer co-extruded film for a multi-chamber bag for pharmaceutical packaging according to claim 4, characterized in that: The reinforcement mechanism comprises a bracket (7) arranged on the feeding barrel (3), a mounting frame (10) being arranged on the bracket (7), a pushing electric cylinder (11) being arranged on the mounting frame (10), a spring (30) being arranged on the telescopic rod of the pushing electric cylinder (11), and two reinforcement slide bars (27) being slidably mounted on the mounting frame (10), a push wheel (31) being connected between the two reinforcement slide bars (27), a fixing rod (28) being arranged on the reinforcement slide bar (27), the fixing rod (28) being butt-jointed with the fixing hole (1201), and a pushing portion (29) being arranged on the reinforcement slide bar (27), the pushing portion (29) being pushed by the spring (30).

6. The device for preparing a non-PVC multi-layer co-extruded film for a multi-chamber bag for pharmaceutical packaging according to claim 1, characterized in that: The bottom of the extrusion box (8) is provided with a motor three (18) and a screw rod three (19); the output shaft of the motor three (18) is provided with a belt mechanism for driving the screw rod three (19); the screw rod three (19) and the bottom of the sealing plate (12) are fixed with a spiral pair.

7. The device for preparing a non-PVC multi-layer co-extruded film for a multi-chamber bag for pharmaceutical packaging according to claim 1, characterized in that: A maintenance mechanism is arranged on the base (1) and below the extrusion box (8), the maintenance mechanism comprising a moving motor (16) and a moving belt (15) arranged on the base (1), the moving motor (16) being used to drive the moving belt (15); a maintenance slide (20) is slidably mounted on the base (1), the maintenance slide (20) is attached to the moving belt (15), a motor four (21) and a screw rod four (22) are arranged on the maintenance slide (20), the motor four (21) is used to drive the screw rod four (22), a slide four (23) is slidably mounted on the maintenance slide (20), the slide four (23) and the screw rod four (22) form a spiral pair, a control electric cylinder (24) is arranged on the slide four (23), a maintenance motor (25) is arranged on the telescopic rod of the control electric cylinder (24), and a maintenance unit (26) is arranged on the output shaft of the maintenance motor (25).

8. The device for preparing a non-PVC multi-layer co-extruded film for a multi-chamber bag for pharmaceutical packaging according to claim 1, characterized in that: The cooling mechanism comprises a cooling water tank (32) and a spray box (33) arranged on the base (1); a spray control electric cylinder (34) is arranged on the spray box (33); a spray part (35) is arranged on the telescopic rod of the spray control electric cylinder (34); the spray part (35) is connected to the cooling water tank (32); the adsorption mechanism comprises a position electric cylinder (36) arranged on the base (1); a position slide seat (43) is arranged on the telescopic rod of the position electric cylinder (36); an adsorption cylinder (42) and a rotating motor (44) are arranged on the position slide seat (43); the rotating motor (44) is used to drive the adsorption cylinder (42) and the rotating motor (44) to move ... A movable adsorption cylinder (42) is provided with an adsorption layer attached to the surface of the adsorption cylinder (42) for adsorbing and removing moisture from the wire material; the adsorption mechanism also includes a motor (37) and a screw (38) which are arranged on the base (1) and located above and below the adsorption cylinder (42); the motor (37) is used to drive the screw (38); a slide seat (39) is slidably mounted on the base (1); the slide seat (39) and the screw (38) form a spiral pair; a scraping electric cylinder (40) is provided on the slide seat (39); and a scraping ring (41) is provided on the telescopic rod of the scraping electric cylinder (40).

9. The device for preparing a non-PVC multi-layer co-extruded film for a multi-chamber bag for pharmaceutical packaging according to claim 1, characterized in that: The winding mechanism comprises an airflow box (45) on the base (1), a winding motor (46) and an emergency winding drum (47), the airflow box (45) being connected to one end of the emergency winding drum (47), the winding motor (46) being used to drive the emergency winding drum (47), through holes being arranged in an array on the emergency winding drum (47), the wire material passing through the through holes, air holes being arranged on the inner circumference of the through holes, each through hole being connected to the airflow box (45) through the air holes, so as to absorb and remove moisture remaining on the wire material; the material cutting mechanism comprises a collecting box (48) and a pelletizing box (49) arranged on the base (1), a pelletizing electric cylinder (50) being arranged on the pelletizing box (49), and a pelletizing portion (51) being arranged on the telescopic rod of the pelletizing electric cylinder (50).

10. A method for preparing a non-PVC multi-layer co-extruded film for multi-chamber bags for pharmaceutical packaging, characterized in that: The following steps are involved: Raw material mixing and granulation:

1. Mixing of raw materials; 2. Twin screw extruder mixing and extrusion; 3. Cooling the strips; 4. Pelletizing and collecting materials; Film blowing process:

1. Vacuum suction to the raw material extruder; 2. Screw extrusion multi-layer die head; 3. Membrane bubble inflation: through air compressor, dry filtration, 0.01um end filtration; 4. Membrane bubble cooling: through RO water production, low temperature heat exchanger, 0.22um ultrafiltration; 5. Rotational traction with herringbone splint; 6. Correction and rolling.

Images