Biological reagent filling machine
Through the collaborative design of the drive mechanism and auxiliary mechanism, the accurate and continuous filling of the biological reagent filling machine is achieved, solving the problems of inaccurate filling and low efficiency caused by low automation, and improving production efficiency and equipment stability.
Patent Information
- Application Number
- CN202510714891.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-05-30
- Publication Date
- 2025-07-08
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The existing biological reagent filling machines have low automation, and manual operations lead to inaccurate filling doses and low production efficiency, which cannot meet the needs of large-scale production.
The drive mechanism and auxiliary mechanism work together, and the precise alignment of the test tube and the vertical lifting and lowering of the filling cylinder are achieved through components such as rotating sleeves, stress blocks, limiting grooves, etc., ensuring the continuous and stable filling process and reducing the frequency of manual intervention.
It realizes automatic switching of multiple stations, improves filling efficiency and consistency, reduces the frequency of manual intervention, improves the stability and production efficiency of the filling process, and extends the service life of the equipment.
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Figure CN120270611A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of biological reagent filling, and specifically provides a biological reagent filling machine. Background Art
[0002] Biological reagents refer to biological materials or organic compounds related to life science research, as well as reagents for clinical diagnosis and medical research. Due to the wide scope and rapid development of life science, there is a wide variety of such reagents with complex properties.
[0003] For example, the "Biological Reagent Filling Machine" with the publication number: CN116854013A includes a bottom plate and a filling machine body arranged on the bottom plate. The filling machine body includes a moving head, and a filling pipe is arranged at the bottom of the moving head. The upper side wall of the bottom plate is connected to a conveyor belt through a conveying mechanism, and a plurality of placing mechanisms for placing reagent bottles are arranged on the conveyor belt.
[0004] However, in the prior art, due to the low degree of automation, the filling of biological reagents relies on a large amount of manual operations, which not only greatly increases the labor cost expenditure of enterprises, but also brings many quality and efficiency problems. On the one hand, manual filling is significantly affected by individual differences. Different operators have large differences in techniques, strengths, and proficiency levels, making it difficult to ensure the accuracy of each filling dose. Even for the same operator, operation deviations are likely to occur after long-term work. On the other hand, since multiple reagents cannot be filled continuously, the production needs to be carried out one by one, resulting in process interruptions. After each reagent filling is completed, preparatory work such as container replacement and parameter adjustment is required. These additional operations greatly extend the overall production cycle and are difficult to meet the requirements of large-scale production. Summary of the Invention
[0005] The purpose of the present invention is to provide a biological reagent filling machine to solve the problem in the above background art that manual filling is significantly affected by individual differences, different operators have large differences in techniques, strengths, and proficiency levels, and it is difficult to ensure the accuracy of each filling dose.
[0006] To achieve the above purpose, the present invention provides the following technical solution: A biological reagent filling machine includes a filling table and a filling cylinder above it. A driving mechanism is installed inside the filling table, and an auxiliary mechanism is installed on one side of the driving mechanism. The driving mechanism includes a rotating rod and a central rod. A rotating sleeve is slidably sleeved on the outer surface of the middle part of the rotating rod. A second driving block is fixedly connected to the outer surface of the rotating sleeve. A convex block matching the rotating sleeve is fixedly connected to the outer surface of the rotating rod. The central rod is rotatably connected to the middle part of the filling table, and a rotating plate is fixedly connected to the outer surface of the bottom end of the central rod. A plurality of stress blocks are fixedly connected to the bottom of the rotating plate. The second driving block is slidably connected to the stress blocks. A rotating platform is fixedly connected to the outer surface of the top end of the central rod. A plurality of storage tubes are fixedly connected to the bottom end of the rotating platform, and a plurality of limiting grooves are formed on the outer surface of the top end of the rotating platform.
[0007] Preferably, a first driving block is fixedly connected to the outer surface of one end of the rotating rod, and a limiting block is fixedly connected to the outer surface of one end of the rotating rod. A plurality of bearing brackets are rotatably connected to the outer surface of the rotating rod.
[0008] Preferably, the auxiliary mechanism includes a swing rod. One end of the swing rod is rotatably connected to a first support frame, and the bottom of the first support frame is fixedly connected to the filling table.
[0009] Preferably, a driving wheel is rotatably connected to the side wall of one end of the swing rod, and a stress wheel is rotatably connected to the side wall of the other end of the swing rod. One end of the stress wheel abuts against the first driving block.
[0010] Preferably, a second support frame is arranged on one side of the first support frame, and a fixed block is fixedly connected to the side wall of the top end of the second support frame.
[0011] Preferably, a limiting wheel is rotatably connected to the inner side of one end of the fixed block, and the limiting wheel abuts against the limiting block.
[0012] Preferably, a lifting rod is fixedly connected to the side wall of the filling cylinder. A limiting sleeve is slidably connected to the outer surface of the lifting rod, and the bottom of the limiting sleeve is fixedly connected to the top of the filling table.
[0013] Preferably, a stress rod is fixedly connected to the bottom end of the limiting sleeve, and the bottom of the stress rod abuts against the top of the driving wheel.
[0014] Preferably, a driving motor is installed on the inner top of the filling table. The output end of the driving motor is fixedly connected to a belt transmission assembly. A gearbox is installed in the inner cavity of the filling table, and the input end of the gearbox is fixedly connected to the belt transmission assembly.
[0015] Preferably, one end of the rotating rod is fixedly connected to the output end of the gearbox, and the bottom of the bearing bracket is fixedly connected to the filling table.
[0016] Compared with the prior art, the beneficial effects of the present invention are: 1. In the present invention, the driving motor transmits power to the gear box smoothly through the belt assembly, and then transmits it to the rotating rod through the speed change diversion, so that it drives multiple key components to rotate in coordination. Under the action of the protrusions arranged on the periphery of the rotating rod, the rotating sleeve and the second driving block are sequentially linked, and the multiple force blocks and the rotating plate are pushed to move in turn, so as to realize the segmented and precise rotation of the rotating platform. Each test tube storage position can be accurately aligned to the filling position during the rotation process, ensuring that the filling process is continuous and stable with minimal error. The entire system can realize automatic switching and efficient operation of multiple stations, greatly improving the filling efficiency and consistency, and effectively reducing the frequency of manual intervention.
[0017] 2. In the present invention, the first driving block is driven to move periodically by the rotating rod, and the lifting power is transmitted to the driving wheel by the linkage structure of the force wheel and the swing rod using the lever principle, which then drives the limit sleeve and the lifting rod to realize the vertical lifting of the filling cylinder. During the lifting process, the lifting rod is constrained by the double-layer limit structure to avoid shaking, thereby ensuring that the filling cylinder is accurately inserted into the test tube. After the filling is completed, the structure returns to its initial position under the action of gravity, and cooperates with the precise switching of the rotating platform to realize efficient and automated continuous filling. The entire system has coherent movements and precise control, which not only ensures the docking accuracy between the syringe and the test tube during filling, but also improves the stability and efficiency of the filling process, significantly reduces manual intervention, and improves the overall production efficiency and finished product quality.
[0018] 3. In the present invention, the precise coordination among the limiting block, the limiting wheel and the fixed block realizes the stable control of the rotating mechanism under high-frequency operation. The limiting block rotates in a controlled manner under the drive of the rotating rod, and its motion path is precisely guided by the structure of the limiting wheel to ensure a stable trajectory without deviation. The fixed block provides additional support and reaction force to further disperse the load and impact during the rotation process, and effectively prevents shaking or tilting caused by inertia. The three work together to form a multi-point constraint system, so that the limiting block always maintains a stable operation within the designed track, avoiding structural looseness and positioning misalignment. In long-term, high-intensity automated filling operations, this design ensures the operating accuracy of each component and the stability of the system, reduces mechanical wear, and improves the reliability and service life of the equipment. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 This is a schematic diagram of the overall structure of a biological reagent filling machine of the present invention; Figure 2 It is a partial structural schematic diagram of a biological reagent filling machine of the present invention; Figure 3 This is a schematic diagram of the structure of a rotating plate and a lifting rod of a biological reagent filling machine of the present invention; Figure 4 It is a structural schematic diagram of a driving mechanism in a biological reagent filling machine of the present invention; Figure 5This is a partial structural schematic diagram of the driving mechanism in a biological reagent filling machine of the present invention; Figure 6 This is a structural schematic diagram of the rotating rod in a biological reagent filling machine of the present invention; Figure 7 This is a structural schematic diagram of the driving mechanism and the auxiliary mechanism in a biological reagent filling machine of the present invention.
[0020] In the figure: 1, filling table; 2, rotating platform; 21, limiting groove; 22, storage tube; 3, filling cylinder; 31, lifting rod; 32, limiting sleeve; 33, stress rod; 4, driving mechanism; 41, driving motor; 42, belt drive assembly; 43, gearbox; 44, rotating rod; 441, first driving block; 442, limiting block; 443, convex block; 45, bearing bracket; 46, central rod; 47, rotating plate; 48, stress block; 49, second driving block; 491, rotating sleeve; 5, auxiliary mechanism; 5, auxiliary mechanism; 51, first support frame; 52, second support frame; 53, swinging rod; 54, driving wheel; 55, fixed block; 56, limiting wheel; 57, stress wheel. Specific embodiments
[0021] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.
[0022] Embodiment 1: Refer to Figure 1 - Figure 7 As shown: A biological reagent filling machine includes a filling table 1 and a filling cylinder 3 above it. A driving mechanism 4 is installed inside the filling table 1, and an auxiliary mechanism 5 is installed on one side of the driving mechanism 4; The driving mechanism 4 includes a rotating rod 44 and a central rod 46. A rotating sleeve 491 is slidably sleeved on the outer surface of the middle part of the rotating rod 44. A second driving block 49 is fixedly connected to the outer surface of the rotating sleeve 491. A convex block 443 matching the rotating sleeve 491 is fixedly connected to the outer surface of the rotating rod 44. The central rod 46 is rotatably connected to the middle part of the filling table 1, and a rotating plate 47 is fixedly connected to the outer surface of the bottom end of the central rod 46. A plurality of stress blocks 48 are fixedly connected to the bottom of the rotating plate 47. The second driving block 49 is slidably connected to the stress blocks 48. A rotating platform 2 is fixedly connected to the outer surface of the top end of the central rod 46. A plurality of storage tubes 22 are fixedly connected to the bottom end of the rotating platform 2, and a plurality of limiting grooves 21 are opened on the outer surface of the top end of the rotating platform 2.
[0023] In this embodiment, during the process of filling biological reagents, a plurality of test tubes to be filled are first stably placed inside the storage tube 22 in sequence, and the test tubes are clamped and positioned through the limiting groove 21, so as to ensure that the test tubes will not shake or displace during subsequent rotation and filling processes, improving the stability and accuracy of filling.
[0024] After the filling device is started, the driving motor 41 provides the initial driving force, and this driving force is smoothly transmitted into the gearbox 43 through the belt transmission assembly 42. After receiving the power, the gearbox 43 changes the speed and distributes the rotational power, and finally transmits it to the rotating rod 44. After receiving the power, the rotating rod 44 starts to rotate, and at the same time drives the first driving block 441 and the limiting block 442 fixedly installed thereon to rotate synchronously.
[0025] During the rotation of the rotating rod 44, the convex block 443 provided on its outer periphery periodically contacts and pushes the rotating sleeve 491. After being acted upon by the convex block 443, the rotating sleeve 491 starts to rotate in a preset direction, and then drives the second driving block 49 connected thereto to rotate synchronously. During the continuous rotation of the second driving block 49, it will sequentially contact and apply a thrust to a plurality of force-receiving blocks 48.
[0026] After each force-receiving block 48 receives the acting force transmitted by the second driving block 49, it starts to push the rotating plate 47 connected thereto to form a rotating action. Through this mechanism linkage design, it is possible to accurately control the rotation angle of the rotating plate 47 in segments and at precise angles based on the number of force-receiving blocks 48, thereby realizing the precise switching of the filling position.
[0027] As the central rod 46 rotates, the rotating platform 2 will also rotate continuously. A plurality of corresponding test tube storage positions are installed on the rotating platform 2. Through the coordinated cooperation of the above structures, each rotation can accurately move the next test tube to be filled to the filling position, realizing efficient and automated continuous filling operations. The entire system not only has precise positioning and switching functions, but also can greatly improve the filling efficiency and reduce the frequency of manual intervention.
[0028] Embodiment Two: Figure 4 - Figure 7As shown in the figure, a first driving block 441 is fixedly connected to the outer surface of one end of the rotating rod 44, and a limiting block 442 is fixedly connected to the outer surface of one end of the rotating rod 44. A plurality of bearing brackets 45 are rotatably connected to the outer surface of the rotating rod 44. The auxiliary mechanism 5 includes a swing rod 53. One end of the swing rod 53 is rotatably connected to a first support frame 51, and the bottom of the first support frame 51 is fixedly connected to the filling table 1. A driving wheel 54 is rotatably connected to one side wall of the swing rod 53, and a force-receiving wheel 57 is rotatably connected to the other side wall of the swing rod 53. One end of the force-receiving wheel 57 abuts against the first driving block 441. A second support frame 52 is arranged on one side of the first support frame 51, and a fixed block 55 is fixedly connected to the top side wall of the second support frame 52. A limiting wheel 56 is rotatably connected to the inner side of one end of the fixed block 55, and the limiting wheel 56 abuts against the limiting block 442. A lifting rod 31 is fixedly connected to the side wall of the filling cylinder 3, and a limiting sleeve 32 is slidably connected to the outer surface of the lifting rod 31. The bottom of the limiting sleeve 32 is fixedly connected to the top of the filling table 1. A force-receiving rod 33 is fixedly connected to the bottom end of the limiting sleeve 32, and the bottom of the force-receiving rod 33 is lapped on the top of the driving wheel 54.
[0029] In this embodiment, when the rotating rod 44 starts to rotate driven by the driving device, the first driving block 441 connected thereto will perform a circular motion accordingly. During this movement, the first driving block 441 will periodically contact and apply a thrust force to the force-receiving wheel 57, causing the force-receiving wheel 57 to shift. At this time, the swing rod 53 connected to the force-receiving wheel 57 starts to swing upward or downward around the first support frame 51 connected to one end thereof as a fulcrum after receiving this thrust force. Since there is a linkage structure between the swing rod 53 and the driving wheel 54, during the swinging process, the swing rod 53 will apply a lifting force to the driving wheel 54 through the lever action.
[0030] During this process, the driving wheel 54 will lift the force-receiving rod 33 connected thereto. The force-receiving rod 33 starts to move along the lifting direction driven by the driving wheel 54, driving the lifting rod 31 slidably connected therein to slide upward. In order to prevent the lifting rod 31 from generating lateral shaking or deviation during the rising process, it is also restricted by the limiting sleeve 32 arranged outside it, so as to ensure that the lifting rod 31 rises stably along the vertical direction. Since the lifting rod 31 is connected to the bottom of the filling cylinder 3, when the lifting rod 31 moves upward, the entire filling cylinder 3 will also be driven to move upward.
[0031] As the rotating rod 44 continues to rotate, the first driving block 441 gradually disengages from the force-receiving wheel 57 and no longer applies a thrust force. At this time, the driving wheel 54 is no longer subjected to the lifting force, and the force-receiving rod 33 loses support and descends by itself under the action of gravity. Driving the lifting rod 31 together with the filling cylinder 3 to fall back to the initial position.
[0032] During the whole process, the control mechanism can be linked according to the rotation rhythm of the rotating platform 2. When the rotating platform 2 accurately switches a test tube to be filled to the filling position, the filling cylinder 3 moves upward under the cooperation of the aforementioned driving structure, and the injection port at its bottom accurately inserts into the interior of the test tube; after the insertion is completed, the control mechanism can start the filling operation and inject the material into the test tube. After the filling is completed, the filling cylinder 3 descends again with the lifting rod 31 and exits from the test tube. Subsequently, the rotating platform 2 continues to rotate to switch to the next test tube and prepare for the next round of filling.
[0033] Embodiment 3: According to Figure 1 - Figure 7 As shown, a driving motor 41 is installed at the inner top of the filling table 1. The output end of the driving motor 41 is fixedly connected with a belt transmission assembly 42. A gearbox 43 is installed in the inner cavity of the filling table 1, and the input end of the gearbox 43 is fixedly connected with the belt transmission assembly 42. One end of a rotating rod 44 is fixedly connected with the output end of the gearbox 43, and the bottom of a bearing bracket 45 is fixedly connected with the filling table 1.
[0034] In this embodiment, as the rotating rod 44 starts to drive the limiting block 442 to rotate, the limiting block 442 realizes controlled rotation under the limiting action of the limiting wheel 56, so as to ensure the stability of its trajectory during the movement process and avoid shaking or deviation. The limiting wheel 56 not only plays a physical limiting role, but also accurately guides the movement path of the limiting block 442 through its set shape structure and position, so that it always maintains a stable operation within the designed track.
[0035] During this process, the fixed block 55 provides an additional support point and reaction force, and together with the limiting wheel 56, constitutes a stable mechanical constraint system, so that the limiting block 442 will not shift or tilt during rotation. The fixed block 55 effectively disperses the load and impact brought by rotation through its fitting surface or cooperation structure with the limiting block 442, and further improves the balance and stability during the rotation process.
[0036] Since the limiting block 442 is always in a controlled state during the whole rotation process and realizes stable operation under the combined action of the multi-point limiting structure, even during long-term and high-frequency filling operations, it can still maintain its working posture unchanged and avoid positioning deviation caused by structural loosening or wear. This not only improves the filling accuracy, but also extends the service life of the equipment, and significantly improves the operation stability and efficiency of the production line.
[0037] Usage method and working principle of this device: When filling biological reagents, the test tube is placed inside the storage tube 22 and clamped and fixed through the limiting groove 21. During the filling process, the driving motor 41 drives the belt transmission assembly 42 to start running. The belt transmission assembly 42 transmits the power to the gearbox 43, and the gearbox 43 then transmits the power to the rotating rod 44. When the rotating rod 44 rotates, it will drive the first driving block 441 and the limiting block 442 to move simultaneously. At the same time, during the rotation of the rotating rod 44, the convex block 443 on it will exert a force on the rotating sleeve 491, thereby driving the rotating sleeve 491 to rotate and further driving the second driving block 49 to rotate. As the second driving block 49 continues to rotate, it will exert a force on the force-bearing block 48, and the force-bearing block 48 will drive the rotating plate 47 to rotate after being stressed. The rotation angle is determined by the number of force-bearing blocks 48. When the set angle is reached, the rotating platform 2 can switch to the position of the next test tube to be filled, realizing continuous filling.
[0038] During the rotation of the rotating rod 44, the first driving block 441 will exert a force on the force-bearing wheel 57 during circular motion, causing the swing rod 53 to be driven to swing. At this time, the swing rod 53 uses the first support frame 51 as a fulcrum and cooperates with the driving wheel 54 to form a lever structure, thereby lifting the force-bearing rod 33. Driven by the force exerted by the driving wheel 54, the force-bearing rod 33 will drive the lifting rod 31 to slide upward, and under the guidance of the limiting sleeve 32, the stable rising of the filling cylinder 3 is realized. As the first driving block 441 continues to rotate and disengages from the action on the force-bearing wheel 57, the filling cylinder 3 falls back under the action of gravity, driving the lifting rod 31 and the force-bearing rod 33 to descend. In this way, while the injection port of the filling cylinder 3 moves up and down, the rotating platform 2 also continuously rotates to switch the test tube positions, realizing the sequential filling of the test tubes. When the injection port descends and inserts into the test tube, the filling operation can be completed.
[0039] In addition, when the rotating rod 44 drives the limiting block 442 to rotate, the limiting block 442 can be stably limited under the constraint of the limiting wheel 56. Under the reaction force formed by the fixed block 55 and the limiting wheel 56, the limiting block 442 and the rotating rod 44 maintain stable operation during rotation, avoiding tilting, so as to ensure that the filling mechanism does not shift in position during long-term filling, improving the filling accuracy and stability.
[0040] Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.
Claims
1. A biological reagent filling machine, comprising a filling table (1) and a filling cylinder (3) above it, characterized in that: A driving mechanism (4) is installed inside the filling table (1), and an auxiliary mechanism (5) is installed on one side of the driving mechanism (4). The driving mechanism (4) includes a rotating rod (44) and a central rod (46). A rotating sleeve (491) is slidably sleeved on the outer surface of the middle part of the rotating rod (44). A second driving block (49) is fixedly connected to the outer surface of the rotating sleeve (491). A convex block (443) matching the rotating sleeve (491) is fixedly connected to the outer surface of the rotating rod (44). The central rod (46) is rotatably connected to the middle part of the filling table (1), and a rotating plate (47) is fixedly connected to the outer surface of the bottom end of the central rod (46). A plurality of stress blocks (48) are fixedly connected to the bottom of the rotating plate (47). The second driving block (49) is slidably connected to the stress blocks (48). A rotating platform (2) is fixedly connected to the outer surface of the top end of the central rod (46). A plurality of storage tubes (22) are fixedly connected to the bottom end of the rotating platform (2), and a plurality of limiting grooves (21) are formed in the outer surface of the top end of the rotating platform (2).
2. The biological reagent filling machine according to claim 1, characterized in that: A first driving block (441) is fixedly connected to the outer surface of one end of the rotating rod (44), and a limiting block (442) is fixedly connected to the outer surface of one end of the rotating rod (44). A plurality of bearing brackets (45) are rotatably connected to the outer surface of the rotating rod (44).
3. A biological reagent filling machine according to claim 1, characterized in that: The auxiliary mechanism (5) includes a swinging rod (53). One end of the swinging rod (53) is rotatably connected to a first support frame (51), and the bottom of the first support frame (51) is fixedly connected to the filling table (1).
4. The biological reagent filling machine according to claim 3, wherein: A driving wheel (54) is rotatably connected to the side wall of one end of the swinging rod (53), and a stress wheel (57) is rotatably connected to the side wall of the other end of the swinging rod (53). One end of the stress wheel (57) abuts against the first driving block (441).
5. A biological reagent filling machine according to claim 4, characterized in that: A second support frame (52) is arranged on one side of the first support frame (51), and a fixed block (55) is fixedly connected to the side wall of the top end of the second support frame (52).
6. The biological reagent filling machine according to claim 5, wherein: A limiting wheel (56) is rotatably connected to the inner side of one end of the fixed block (55), and the limiting wheel (56) abuts against the limiting block (442).
7. A biological reagent filling machine according to claim 1, characterized in that: A lifting rod (31) is fixedly connected to the side wall of the filling cylinder (3). A limiting sleeve (32) is slidably connected to the outer surface of the lifting rod (31), and the bottom of the limiting sleeve (32) is fixedly connected to the top of the filling table (1).
8. A biological reagent filling machine according to claim 7, characterized in that: A stress rod (33) is fixedly connected to the bottom end of the limiting sleeve (32), and the bottom of the stress rod (33) abuts against the top of the driving wheel (54).
9. The biological reagent filling machine according to claim 8, wherein: A driving motor (41) is installed on the inner top of the filling table (1). The output end of the driving motor (41) is fixedly connected to a belt transmission assembly (42). A gear box (43) is installed in the inner cavity of the filling table (1), and the input end of the gear box (43) is fixedly connected to the belt transmission assembly (42).
10. A biological reagent filling machine according to claim 2, characterized in that: One end of the rotating rod (44) is fixedly connected to the output end of the gear box (43), and the bottom of the bearing bracket (45) is fixedly connected to the filling table (1).
Citation Information
Patent Citations
Biological reagent filling machine
CN116854013A