Magnetic control vibration capsule and system for treating constipation

Abstract

The invention belongs to the field of medical instruments, and particularly discloses a magnetic control vibration capsule and system for treating constipation. According to the invention, the external magnetic field triggers the reed switch to control the starting and stopping of the vibration motor, a traditional wireless communication control mode is replaced, a power consumption unit does not need to be integrated, the power consumption and the size of the capsule are remarkably reduced, and the endurance time is prolonged; the arrangement of the reed switches is optimized, and a plurality of reed switches are arranged in different directions for orthogonal decoupling, so that the capsule can be stably triggered by an external magnetic field no matter how the posture of the capsule in the intestinal tract changes, the triggering reliability is remarkably improved, and the problem that the reed switches in a single direction fail to trigger is solved; the medicine storage cavity with the medicine feeding holes and the vibration system are integrated, when the capsule works in the intestinal tract, the capsule stimulates intestinal tract movement through vibration and releases a specific treatment solution in a slow release mode, the capsule and the vibration system act synergistically, the treatment effect is improved, and the capsule is particularly suitable for comprehensive intervention of functional slow-transit constipation.

Description

Technical Field

[0001] This application belongs to the field of medical devices, and more specifically, relates to a magnetically controlled vibrating capsule and system for treating constipation. Background Art

[0002] Chronic constipation has become a major health problem globally. In China, the prevalence rate among adults is about 4% - 10%, and it increases significantly with age, especially under the background of population aging. Long-term constipation not only causes complications such as abdominal distension, abdominal pain, and hemorrhoids, but also is closely related to an increased risk of cardiovascular and cerebrovascular events, seriously affecting the quality of life of patients and consuming medical resources. A vibrating capsule is a swallowable micro-medical device, usually encapsulated by biocompatible materials, and internally integrated with a micro-vibrating motor, a control circuit, and an energy module (such as a micro-battery). Through preset or real-time regulated mechanical vibration, the vibrating capsule stimulates the intestinal wall and enhances the intestinal peristalsis function.

[0003] As a physical therapy method, vibrating capsules have become a new direction for constipation treatment, and companies such as China's AnHan Medical and Israel's Vibrant Gastro have launched related products. There is still significant room for improvement in existing vibrating capsule products or methods in the following aspects: 1) Size and battery life issues. For example, although the vibrating capsule in AnHan Medical's CN113384385A patent has rich functions and good interaction performance with the outside, due to the necessity of integrating a wireless communication unit (such as a radio frequency antenna, an RF transceiver module, and a PCB unit), the capsule size is large, and the power consumption of its redundant devices results in insufficient battery life. 2) Trigger reliability issues. Some existing vibrating capsules use an external magnetic field to control vibration, such as the vibrating capsule in AnHan Medical's CN111481418A patent. Although it can effectively reduce the energy consumption and size of the capsule, when using a single reed switch trigger mode, the directionality of the magnetic field and the attitude of the reed switch will affect the trigger reliability. Specifically, if the direction of the externally applied magnetic field does not match the reed switch (for example, when the reed switch is in a horizontal excitation state, the magnetic field is perpendicular to the reed switch), there is a risk of trigger failure, affecting the treatment effect. 3) Single function issues. Currently, most vibrating capsules only rely on physical vibration without other additional effects, resulting in low curative effects. Summary of the Invention

[0004] Aiming at the defects of the prior art, the purpose of this application is to provide a magnetically controlled vibrating capsule and system for treating constipation, aiming to solve the problems of short battery life, large volume, poor trigger reliability, and single function in the prior art.

[0005] The first aspect of this application relates to a magnetically controlled vibrating capsule for treating constipation, including: a housing, and a vibrating motor, a multi-reed switch with orthogonal decoupling, and a power supply fixed inside the housing; The orthogonally decoupled multi-reed switches are connected in parallel with each other and have a default off state, and are used to control the start and shutdown of the vibration motor in response to the presence of an external magnetic field; A medicine storage cavity with a medicine delivery hole is provided on the housing, and is used to slowly release the liquid medicine in the cavity while the capsule vibrates.

[0006] Preferably, the orthogonally decoupled multi-reed switches are composed of two or three orthogonally arranged reed switches.

[0007] Preferably, the orthogonally arranged reed switches are fixed on the bare PCB through copper wires or solder joints to achieve parallel connection, and only the multi-reed switches are provided on the bare PCB.

[0008] Preferably, the liquid medicine in the cavity includes at least one of laxatives, prokinetic drugs, probiotic drugs, and intestinal lubricating drugs.

[0009] Preferably, the diameter of the medicine delivery hole is 0.3 mm - 0.5 mm.

[0010] Preferably, the surface of the medicine delivery hole is covered with an enteric film.

[0011] Preferably, in the axial direction of the vibrating capsule, the orthogonally decoupled multi-reed switches and the vibration motor are respectively located on both sides of the power supply.

[0012] Preferably, in the radial direction of the vibrating capsule, the medicine storage cavity with a medicine delivery hole is symmetrically arranged on both sides of the vibration motor.

[0013] Preferably, the number of medicine storage cavities is one or more, and each medicine storage cavity is independent or connected.

[0014] The second aspect of the present application relates to a magnetically controlled vibrating capsule system for treating constipation, which is characterized in that it includes the magnetically controlled vibrating capsule as described in the first aspect and an external magnetic field generating device; The external magnetic field generating device is used to provide a magnetic field to the vibrating magnetically controlled capsule.

[0015] Generally speaking, compared with the prior art through the above technical solutions conceived by the present application, the following beneficial effects are obtained: (1) The present application provides a magnetically controlled vibrating capsule for treating constipation. On the one hand, by controlling the reed switch through an external magnetic field to control the start and shutdown of the vibration motor, it replaces the traditional wireless communication control method, eliminates the need to integrate power-consuming units such as radio frequency antennas and RF modules, significantly reduces the power consumption and volume of the capsule, and extends the battery life; on the other hand, the present application optimizes the layout of the reed switches, and multiple reed switches are arranged in different directions for orthogonal decoupling, ensuring that no matter how the posture of the capsule changes in the intestine, it can be stably triggered by the external magnetic field, significantly improving the triggering reliability and overcoming the problem of triggering failure of the reed switch in a single direction.

[0016] (2) The present application provides a magnetically controlled vibrating capsule for treating constipation, which integrates a medicine storage cavity with a dosing hole and a vibration system to construct a dual treatment mechanism of "physical vibration + drug release". When working in the intestine, the capsule stimulates intestinal peristalsis through vibration and slowly releases a specific treatment solution (such as laxatives, prokinetic drugs, probiotic preparations or intestine-lubricating drugs, etc.) at the same time. The two work together to improve the treatment effect, and it is particularly suitable for the comprehensive intervention of functional slow transit constipation. Description of the Drawings

[0017] Figure 1 It is a schematic structural diagram of a magnetically controlled vibrating capsule for treating constipation provided by an embodiment of the present application.

[0018] Figure 2 It is a schematic diagram of the principle of the reed switch combination provided by an embodiment of the present application.

[0019] In all the drawings, the same reference numerals are used to represent the same elements or structures, where: 1 is an orthogonal decoupled multi-reed switch, 2 is a bare PCB board, 3 is a power supply, 4 is a vibration motor, 5 is a housing, 6 is a medicine storage cavity, and 7 is a dosing hole. Detailed Embodiments

[0020] In order to make the purpose, technical solutions and advantages of the present application clearer, the present application will be further described in detail below with reference to the drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0021] The embodiments of the present application will be described below with reference to the drawings in the embodiments of the present application.

[0022] As Figure 1 shown, the present application discloses a magnetically controlled vibrating capsule for treating constipation, including: a housing 5, a vibration motor 4, an orthogonal decoupled multi-reed switch 1 and a power supply 3 fixed in the housing 5; the orthogonal decoupled multi-reed switches 1 are connected in parallel with each other and have a default off state, and are used to control the start and shutdown of the vibration motor 4 in response to the presence of an external magnetic field; the housing is provided with a medicine storage cavity 6 with a dosing hole 7 for slowly releasing the liquid medicine in the cavity while the capsule vibrates.

[0023] Preferably, the orthogonal decoupled multi-reed switch is composed of two or three orthogonally placed reed switches.

[0024] For a single reed switch, when the external magnetic field is parallel to the direction of the reed switch, the reed switch is turned on, as Figure 2 shown in a in Figure 2 ; when the external magnetic field is perpendicular to the direction of the reed switch, the reed switch cannot be turned on, as

[0025] For a two-dimensional orthogonal reed switch, when the external magnetic field direction is along the direction of a certain reed switch, the minimum triggering magnetic field is , one reed switch conducts, and the other reed switch cannot conduct, as shown in Figure 2 c in

[0026] For a two-dimensional orthogonal reed switch, and the triggering magnetic fields of the two reed switches are the same and both are , the maximum external triggering magnetic field is , the corresponding magnetic field direction forms a 45° angle with the reed switch. At this time, both reed switches conduct, as shown in Figure 2 d in

[0027] For a three-dimensional orthogonal reed switch, and the triggering magnetic fields of the three reed switches are the same and both are , the maximum external triggering magnetic field is , the corresponding magnetic field direction forms an angle of with the reed switch. At this time, all three reed switches conduct, as shown in Figure 2 e in

[0028] Preferably, the orthogonally placed reed switch 1 is fixed on the bare PCB 2 by copper wires or solder joints to achieve parallel connection.

[0029] It should be noted that only multi-reed switches and parallel wiring are provided on the bare PCB 2, and the capsule size is basically not affected.

[0030] Preferably, the liquid medicine in the cavity includes at least one of constipation treatment drugs such as laxatives, prokinetic drugs, probiotic drugs, and intestinal moistening drugs.

[0031] Preferably, the diameter of the drug delivery hole 7 is 0.3 mm - 0.5 mm.

[0032] It should be noted that if the size of the drug delivery hole is too large, the drug release rate will be relatively fast, shortening the treatment time; if it is too small, the drug release rate will be relatively slow and the drug concentration cannot be maintained. The above preferred size can ensure a moderate drug release rate and achieve a better treatment effect. Correspondingly, the drug release speed can be adjusted by changing the pore diameter of the micropores within a certain range.

[0033] Preferably, the surface of the drug delivery hole 7 is covered with an enteric film.

[0034] It should be noted that when the surface of the drug delivery hole is covered with an enteric film, it can dissolve in the intestine when the vibrating capsule reaches it, but does not dissolve in other organs such as the stomach and esophagus during swallowing, thus ensuring targeted drug release in the intestine.

[0035] Preferably, in the axial direction of the vibrating capsule, the orthogonally decoupled multi-reed switch 1 and the vibrating motor 4 are respectively located on both sides of the power supply 3.

[0036] It should be noted that the present application preferably adopts the above layout to reduce the influence of the motor vibration on the reed switch and avoid mis-triggering or turning off.

[0037] Preferably, in the radial direction of the vibration capsule, the medicine storage cavity 6 with a medicine delivery hole is symmetrically arranged on both sides of the vibration motor 4.

[0038] It should be noted that the present application preferably adopts the above layout, and the medicine storage cavity is close to the vibration motor, making the best use of the vibration effect to achieve drug release.

[0039] Preferably, the number of the medicine storage cavities 6 is one or more, and each medicine storage cavity is independent or connected.

[0040] It should be noted that when the medicine storage cavities are independent, different types of drugs can be conveniently carried independently; when the medicine storage cavities are connected, the volume of the carried drugs can be enlarged, enhancing the treatment effect.

[0041] The power supply involved in the present application includes but is not limited to lithium batteries, silver oxide batteries, rechargeable batteries, and wireless charging devices.

[0042] On the basis of the above, the present application proposes a magnetically controlled vibration capsule system for treating constipation, including the magnetically controlled vibration capsule as described above and an external magnetic field generating device; the external magnetic field generating device is used to provide a magnetic field to the vibration magnetically controlled vibration capsule.

[0043] The working principle of the whole system is as follows: (1) When the capsule is in storage or before use, it is in a magnetic field-free environment and the internal circuit is disconnected; (2) The user swallows the capsule and waits for 6 - 8 hours to ensure that the capsule has entered the intestine and the enteric-coated film has dissolved; (3) The user wears the wearable magnetic control device, and the external magnetic field generated by it makes the reed switch conduct, starting the vibration of the vibration capsule, and at the same time releasing the therapeutic drug carried by the capsule through the micropores. After vibrating for 10 - 15 minutes, a treatment is completed; (4) The user removes the wearable magnetic control device, turns off the reed switch, and the motor stops vibrating, completing a single treatment; (5) After a certain time interval, the user wears the wearable magnetic control device again to reactivate the external magnetic field and start the capsule to continue vibrating and releasing drugs. The whole treatment process can be cycled multiple times by wearing or removing the magnetic control device according to the actual situation.

[0044] Preferably, the external magnetic field is generated by a wearable magnetic control device. The device adopts a structural design of embedding hard magnetic particles in a soft matrix. The user can realize the on / off control of the magnetic field through simple wearing and removing actions, without electronic control components, with simple operation, high safety, and suitable for convenient deployment in a family or daily use environment.

[0045] Preferably, the wearable magnetic field generating device is a magnetic soft body made of neodymium iron boron particles coated with silica gel. The triggering magnetic field of a single reed switch selected is less than 0.6 mT, and the magnetic soft body generates a magnetic field of more than 1.04 mT (0.6 mT × 1.732) at the farthest distance from its surface (the human body center area, generally 15 - 25 cm).

[0046] Embodiment In this embodiment, the power source is a lithium battery, the vibration motor is a coreless motor, the rotation speed is from 10 revolutions per minute to 1000 revolutions per minute, the theoretical endurance time at the maximum motor rotation speed is not less than 2 hours, the diameter of the drug delivery hole is 0.4 mm, the size of the entire magnetic control capsule is 11.5 mm × 11.5 mm × 25 mm, and the weight is about 3 grams.

[0047] It should be understood that expressions such as "including" and "may include" that can be used in this application indicate the existence of the disclosed functions, operations, or constituent elements, and do not limit one or more additional functions, operations, and constituent elements. In this application, terms such as "including" and / or "having" can be interpreted as indicating a specific property, number, operation, constituent element, component, or a combination thereof, but cannot be interpreted as excluding the existence or possibility of addition of one or more other properties, numbers, operations, constituent elements, components, or a combination thereof.

[0048] In addition, in this application, the expression "and / or" includes any and all combinations of the associated listed words. For example, the expression "A and / or B" can include A, can include B, or can include both A and B.

[0049] In the description of the embodiments of this application, it should be noted that unless otherwise clearly specified and limited, the term "connection" should be understood in a broad sense. For example, "connection" can be a detachable connection or a non-detachable connection; it can be a direct connection or an indirect connection through an intermediate medium. Among them, "fixed connection" means that they are connected to each other and the relative position relationship after connection remains unchanged. "Rotational connection" means that they are connected to each other and can rotate relative to each other after connection. "Sliding connection" means that they are connected to each other and can slide relative to each other after connection. The orientation terms mentioned in the embodiments of this application, such as "top", "bottom", "inner", "outer", "left", "right", etc., are only with reference to the direction of the attached drawings. Therefore, the orientation terms used are for better and clearer illustration and understanding of the embodiments of this application, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus cannot be understood as a limitation to the embodiments of this application.

[0050] In addition, in the embodiments of the present application, mathematical concepts such as symmetry, equality, parallelism, and perpendicularity are mentioned. These definitions are based on the current technological level, rather than absolute and strict definitions in the mathematical sense. A small deviation is allowed, and approximate symmetry, approximate equality, approximate parallelism, approximate perpendicularity, etc. are all acceptable. For example, when it is stated that A is parallel to B, it means that A is parallel to B or approximately parallel to B, and the included angle between A and B can be between 0 degrees and 10 degrees. When it is stated that A is perpendicular to B, it means that A is perpendicular to B or approximately perpendicular to B, and the included angle between A and B can be between 80 degrees and 100 degrees.

[0051] The above is only the specific implementation manner of the present application, but the protection scope of the present application is not limited thereto. Any person skilled in the art within the technical scope disclosed by the present application can easily think of changes or substitutions, which should all be covered by the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.

Claims

1. A magnetically controlled vibrating capsule for treating constipation, characterized in that, Comprising: A housing, a vibration motor fixed within the housing, a multi-reed switch with orthogonal decoupling, and a power source; The multi-reed switch with orthogonal decoupling is connected in parallel with each other and has a default off state, and is used to control the start and shutdown of the vibration motor in response to the presence of an external magnetic field; A medicine storage cavity with a medicine delivery hole is provided on the housing, and is used to slowly release the liquid medicine in the cavity while the capsule vibrates.

2. The magnetically controlled vibrating capsule according to claim 1, wherein The multi-reed switch with orthogonal decoupling is composed of two or three reed switches placed orthogonally.

3. The controlled-magnetic-vibration capsule according to claim 2, wherein The reed switches placed orthogonally are fixed on the bare PCB board through copper wires or solder joints to achieve parallel connection, and only the multi-reed switch is provided on the bare PCB board.

4. The magnetically controlled vibrating capsule according to claim 1, wherein The liquid medicine in the cavity includes at least one of laxatives, prokinetic drugs, probiotic drugs, and intestinal lubricant drugs.

5. The magnetically controlled vibrating capsule according to claim 1, wherein The diameter of the medicine delivery hole is 0.3 mm - 0.5 mm.

6. The magnetically controlled vibrating capsule according to claim 1, wherein The surface of the medicine delivery hole is covered with an enteric membrane.

7. The magnetically controlled vibrating capsule according to claim 1, wherein In the axial direction of the vibrating capsule, the multi-reed switch with orthogonal decoupling and the vibration motor are respectively located on both sides of the power source.

8. The magnetically controlled vibrating capsule according to claim 1, wherein In the radial direction of the vibrating capsule, the medicine storage cavity with a medicine delivery hole is symmetrically arranged on both sides of the vibration motor.

9. The magnetically controlled vibrating capsule according to claim 8, characterized in that, The number of medicine storage cavities is one or more, and each medicine storage cavity is independent or connected to each other.

10. A magnetically controlled vibrating capsule system for treating constipation, characterized in that, Comprising the magnetically controlled vibrating capsule according to any one of claims 1 to 9 and an external magnetic field generating device; The external magnetic field generating device is used to provide a trigger magnetic field to the magnetically controlled vibrating capsule.

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