Sand blasting method for pure titanium implant material and sand-blasted pure titanium implant material

Abstract

The invention relates to a sand blasting method for a pure titanium implant material and the sand-blasted pure titanium implant material. The method comprises the steps of sand blasting pretreatment, a sand blasting process and cleaning after sand blasting which are controlled through specific technological parameters, finished product cleaning liquid is adopted in cooperation with ultrasonic cleaning in the sand blasting pretreatment, and the cleanliness of a to-be-machined material is ensured; key parameters such as aluminum oxide particle size, sand blasting machine pressure, nozzle distance and time are accurately set in the sand blasting process; and after sand blasting, residues are removed through ultrasonic cleaning again. According to the method, the effect of remarkably improving the surface roughness of the pure titanium implant material is achieved, so that the surface roughness of the pure titanium implant material meets the requirements of the biomedical field on the surface performance of the material, meanwhile, the process stability and repeatability are guaranteed, and finally the high-quality pure titanium implant material with the surface roughness Ra being larger than or equal to 1.05 and smaller than or equal to 2.7 microns is obtained.

Description

Technical Field

[0001] The present application relates to the field of implant materials, and particularly to a sandblasting method for a pure titanium implant material and the pure titanium implant material after sandblasting. Background Art

[0002] Metallic titanium and titanium alloys are widely used in implant materials due to their excellent mechanical properties, relatively close elastic modulus to bone, and good biocompatibility. However, as implant materials, titanium and titanium alloys still have the problem of low bioactivity. Usually, surface modification treatments are carried out on the surfaces of titanium and titanium alloys used as implant materials. Among these surface modification treatment technologies, there are mainly the following two: coating biomaterials on the titanium metal surface by various methods to improve bioactivity, and these biomaterials include hydroxyapatite coatings, biopolymer coatings, etc.; applying technologies such as sandblasting and acid etching to transform the surface microphysical morphology and chemical composition of the implant, forming a rough and porous surface, increasing the bonding area between the implant material and bone tissue, and clinically accelerating the bone healing rate and improving the bone bonding strength. Due to the high efficiency of traditional dry sandblasting technology, it is currently widely used.

[0003] For example, a method for liquid sandblasting treatment on the surface of an implant material. According to the patent specification, the main technical principle of this patent is to increase the surface roughness of the implant material by performing liquid sandblasting treatment on the surface of the implant material, and no large amount of harmful sandblasting particles will remain. Specifically, this method includes cleaning the implant material with an organic solvent and water, placing the cleaned implant material in a drying oven for drying, and then performing liquid sandblasting treatment on the surface of the implant material to obtain an implant material with increased surface roughness. The liquid sandblasting treatment includes spraying using a uniform suspension of sandblasting particles and a liquid solvent. The sandblasting particles can be at least one particle selected from aluminum oxide, zirconia, cerium dioxide, silicon carbide, titanium dioxide, insoluble phosphates, insoluble calcium salts, and insoluble magnesium salts, and the liquid solvent can be at least one solvent selected from water, ethanol, and acetone. The implant material can be titanium, a titanium alloy, or polyetheretherketone. For the implant material after liquid sandblasting treatment, its surface roughness is 12 to 50 times that of the surface of the implant material after polishing, and the remaining sandblasting particles are significantly reduced.

[0004] Although the above method reduces a part of the remaining sandblasting particles, the surface roughness of the surface implant formed by this method is relatively low, which affects the bone bonding time at the interface between the postoperative bone tissue and the implant. Summary of the Invention

[0005] In order to solve the above problems, the present application provides a sandblasting method for a pure titanium implant material and the pure titanium implant material after sandblasting.

[0006] In a first aspect, a sandblasting method for a pure titanium implant material provided by the present application adopts the following technical solution: A sandblasting method for a pure titanium implant material, comprising the following steps: Pre-treatment before sandblasting: Using a finished cleaning solution, prepare a cleaning solution according to the instructions of the finished cleaning solution. Place the pure titanium implant material to be sandblasted into the prepared cleaning solution and ultrasonically clean for 20 minutes. Then place the pure titanium implant material to be sandblasted into deionized water and ultrasonically clean for 20 minutes. Repeat twice and dry for standby; Sandblasting: Inject alumina particles into the sandblaster, open the air compressor valve, adjust the pressure gauge of the sandblaster, adjust the distance between the pure titanium implant material to be sandblasted and the nozzle, and start sandblasting and timing; Post-sandblasting cleaning: Place the pure titanium implant material after sandblasting into deionized water and ultrasonically clean 2 times, each time for 300 s.

[0007] By adopting the above technical solution, in the pre-treatment step before sandblasting, through multiple ultrasonic cleanings and drying of the pure titanium implant material, impurities on the surface of the material are effectively removed, ensuring a higher quality of the rough morphology formed during the subsequent sandblasting process. In the sandblasting step, by adjusting key parameters such as alumina particles, the pressure of the sandblaster, the distance between the nozzle and the material, and the sandblasting time, a uniform rock-like rough morphology suitable for the standards of medical implants is formed on the surface of pure titanium, increasing the specific surface area of the pure titanium implant material, thereby enhancing its bioactivity and promoting the bone bonding process. The optimized sandblasting process obtains an ideal surface roughness range, meeting the standard requirements of medical implants, providing more surface binding sites for protein adsorption, facilitating the rapid binding of the bone tissue and the implant interface after surgery, shortening the bone healing cycle and improving the bone bonding strength. Placing the pure titanium implant material after sandblasting into deionized water and ultrasonically cleaning 2 times, each time for 300 s can effectively remove the alumina particles attached to the surface of the pure titanium implant material after sandblasting, reducing the influence of residual impurities on the subsequent treatment and implantation effect. Specifically, through two ultrasonic cleanings of 300 seconds each time, the Al residue amount on the surface of pure titanium can be significantly reduced, optimizing the surface quality of the implant material, thereby improving biocompatibility and bone bonding performance.

[0008] Preferably, for the pre-treatment before sandblasting, the specific steps are: the volume ratio of the pure titanium implant material to the prepared cleaning solution is 1:15.

[0009] By adopting the above technical solution, the volume ratio of the pure titanium implant material to the configured cleaning solution in the pre-blasting treatment is set to 1:15, ensuring the sufficiency of the cleaning solution, enabling each piece of pure titanium implant material to be fully surrounded and cleaned by the solution, thereby improving the cleaning effect and the cleanliness of the material surface. Through sufficient soaking and cleaning, impurities on the surface of the pure titanium material are removed more effectively, providing a better surface for subsequent blasting treatment, which helps to improve the blasting effect and product quality. The consistent volume ratio helps to standardize the operation process, ensuring that each batch of pure titanium implant materials can receive the same quality pre-treatment, thereby enhancing the stability and repeatability of the entire blasting process.

[0010] Preferably, the ultrasonic frequency in the ultrasonic cleaning during the pre-blasting treatment is 40 - 80 Hz, and the temperature is adjusted to 50 °C.

[0011] By adopting the above technical solution, the ultrasonic frequency is set in the range of 40 - 80 Hz, and the temperature is adjusted to 50 °C, making the cleaning process more efficient and further improving the cleanliness of the surface of the pure titanium implant material.

[0012] Preferably, the particle size of the alumina particles during the blasting process is 60 - 80 mesh.

[0013] By adopting the above technical solution, the particle size of the alumina particles is controlled between 60 - 80 mesh, which can generate a moderate impact force during the blasting process, ensuring effective processing of the surface of the pure titanium implant material while avoiding problems such as surface damage or insufficient roughness caused by overly large or small particles. Ultimately, the ideal surface roughness is achieved, promoting the bone bonding effect.

[0014] Preferably, the pressure of the sandblasting machine during the blasting process is 0.2 - 0.4 MPa.

[0015] By adopting the above technical solution, controlling the pressure of the sandblasting machine within the range of 0.2 - 0.4 MPa can effectively regulate the impact force on the surface of the pure titanium implant material during the blasting process. Within this pressure range, the blasting particles can bombard the material surface with moderate energy, ensuring the formation of an ideal rough morphology, avoiding problems such as insufficient surface modification caused by too low pressure, and preventing surface damage or excessive erosion of the material caused by too high pressure. Ultimately, the selection of this parameter significantly improves the surface roughness of the pure titanium implant material, which is beneficial to increasing the bone contact area, promoting protein adsorption, and thus improving the bonding performance between the implant and bone tissue.

[0016] Preferably, the distance between the pure titanium implant material to be blasted and the nozzle during the blasting process is 10 - 150 mm.

[0017] By adopting the above technical solution, controlling the distance between the titanium implant material to be sandblasted and the nozzle within the range of 10 - 150 mm can ensure that the acting force of alumina particles on the surface of the titanium implant material during sandblasting is moderate. The sandblasting operation within this distance range not only avoids local over-erosion caused by too short a distance but also prevents energy loss and weakened effect caused by too long a distance, thereby effectively ensuring the formation of a uniform and appropriate surface roughness on the titanium implant material, and further improving its osseointegration performance.

[0018] Preferably, the sandblasting time during the sandblasting process is 15 - 60 s.

[0019] By adopting the above technical solution, controlling the sandblasting time within the range of 15 - 60 s can form an appropriate surface roughness on the titanium implant material, avoiding problems such as insufficient surface topography caused by too short sandblasting time or surface damage caused by too long sandblasting time. Within this time, the effective bombardment of sandblasting particles on the titanium surface forms an interlaced rock ridge structure and irregular pits, significantly increasing the specific surface area of the titanium implant material, which is thus conducive to improving the bonding performance between the implant and bone tissue and promoting the bone healing process.

[0020] Preferably, the frequency of ultrasonic cleaning after sandblasting is 30 - 100 Hz, and the time is 100 - 400 s.

[0021] By adopting the above technical solution, by adjusting the frequency and time of ultrasonic cleaning, it is ensured that the residual sandblasting particles and other pollutants on the surface of the titanium implant material can be completely removed. Within the frequency range of 30 - 100 Hz, ultrasonic waves can generate appropriate vibration energy, effectively breaking the adhesion force between pollutants and the material surface, thereby improving the cleaning efficiency. Appropriate cleaning time and frequency can ensure that while thoroughly cleaning, it will not cause damage to the surface of the titanium implant material, maintaining its integrity and functionality.

[0022] In the second aspect, the present application provides a sandblasted titanium implant material.

[0023] A sandblasted titanium implant material obtained by using the sandblasting method of the titanium implant material described in the first aspect, wherein the surface roughness of the sandblasted titanium implant material is 1.05 ≤ Ra ≤ 2.7 μm.

[0024] By adopting the above technical solution, after the pure titanium implant material is sandblasted, the surface roughness is significantly improved, specifically in the range of 1.05 ≤ Ra ≤ 2.7 μm. This improvement in roughness benefits from the precise control of the alumina particle size, sandblasting machine pressure, distance between the nozzle and the material, and sandblasting time during the sandblasting process, ensuring the formation of a uniform and suitable rock-like rough morphology on the surface of pure titanium. In addition, the ultrasonic cleaning step after sandblasting further optimizes the surface quality. By setting the ultrasonic cleaning frequency to 30 - 100 Hz and the cleaning time to 100 - 400 s, the residual sandblasting particles are effectively removed, reducing the impact on subsequent processing. The finally obtained pure titanium implant material not only has a higher specific surface area but also enhances the bonding ability with bone tissue, promoting the initial stability and long-term bone integration effect during the bone healing process.

[0025] In summary, this application includes at least one of the following beneficial technical effects: 1. By optimizing the sandblasting process parameters, including alumina particle size, sandblasting machine pressure, nozzle distance, and sandblasting time, a uniform rock-like rough morphology can be formed on the surface of the pure titanium implant material, significantly increasing the surface roughness to the range of Ra 1.05 - 2.7 μm, effectively increasing the specific surface area, and promoting protein adsorption and bone tissue bonding; 2. The ultrasonic cleaning steps are adopted before and after sandblasting, especially the ultrasonic cleaning with two different frequency and time settings, which can thoroughly remove the residual sandblasting particles on the surface, reduce the residue of harmful substances, ensure the effect of subsequent acid etching treatment, and further improve the surface quality; 3. Compared with the traditional method, the sandblasting method provided in this application solves the problem of insufficient surface roughness while ensuring high-efficiency production, enhances the mechanical interlocking effect between the implant and bone tissue, shortens the bone healing cycle, and improves the bone bonding strength. Description of the Drawings

[0026] Figure 1 is the flowchart of the sandblasting method for the pure titanium implant material provided in this application.

[0027] Figure 2 is the electron magnifier image of the untreated pure titanium implant material and the pure titanium implant material after being treated in Example 5.

[0028] Figure 3 is the electron microscope image of the untreated pure titanium implant material and the pure titanium implant material after being treated in Example 5.

[0029] Figure 4 is the 3D profilometer image of the untreated pure titanium implant material and the pure titanium implant material after being treated in Example 5. Detailed Description of the Invention

[0030] The following is combined with the attached Figures 1-4A further detailed description of the present application is provided.

[0031] An embodiment of the present application discloses a sandblasting method for a pure titanium implant material. Referring to Figure 1 , the sandblasting method for the pure titanium implant material includes three stages: pre-sandblasting treatment, sandblasting, and post-sandblasting cleaning.

[0032] Specifically, pre-sandblasting treatment: Use a finished cleaning solution, configure a cleaning solution according to the instructions of the finished cleaning solution, place the pure titanium implant material to be sandblasted into the configured cleaning solution, perform ultrasonic cleaning for 20 minutes, and then place the pure titanium implant material to be sandblasted into deionized water for ultrasonic cleaning for 20 minutes; repeat twice and dry for standby; Specifically, the pre-sandblasting treatment includes two core steps: First, use a finished cleaning solution to configure a cleaning solution to ensure that the ratio of the pure titanium implant material to the solution is 1:15; Second, place the material to be sandblasted in this solution, perform ultrasonic cleaning for 20 minutes, then transfer it to deionized water for ultrasonic cleaning for 20 minutes again, repeat twice and dry for standby. During this process, the frequency of the ultrasonic device is set to 40 - 80 Hz, and the temperature is maintained at about 50 °C.

[0033] Sandblasting: Inject alumina particles into the sandblasting machine, open the air compressor valve, adjust the pressure gauge of the sandblasting machine, adjust the distance between the pure titanium implant material to be sandblasted and the nozzle, and start sandblasting and timing.

[0034] Specifically, the operation during sandblasting involves the following key points: Select alumina particles with a particle size range of 60 - 80 mesh (about 125 - 250 μm) to fill into the sandblasting machine, adjust the machine pressure to the range of 0.2 - 0.4 MPa, adjust the distance between the nozzle and the material to be sandblasted to be within the range of 10 - 150 mm, start the system for sandblasting operation, and control the timing range between 15 - 60 seconds.

[0035] Controlling the sandblasting time between 15 - 120 s can form a relatively uniform rock-like rough morphology on the surface of the pure titanium implant, increasing the specific surface area of the pure titanium implant material.

[0036] The particle size, pressure, time, and distance of the sandblasting particles will affect the surface roughness of the pure titanium implant material; Specifically, when the particle size of the sandblasting particles increases, the irregular morphology on the surface of the pure titanium implant material becomes more obvious and the pit diameter is larger; when the pressure increases, the pit depth will be deeper; when the time is extended, the surface roughness will not continuously increase with the extension of time; when the distance increases, the roughness does not change linearly; only by controlling the influencing parameters in sandblasting within the above ranges, on the one hand, an appropriate surface roughness can be formed on the pure titanium implant material; on the other hand, it can meet the efficiency requirements of industrial production.

[0037] In some embodiments, the sandblasting process parameters may be as follows: sandblasting particle size: 60 mesh, 80 mesh, 100 mesh, 120 mesh, 150 mesh; sandblasting pressure: 0.2 MPa, 0.3 MPa, 0.4 MPa, 0.5 MPa, 0.6 MPa; sandblasting distance: 10 mm, 30 mm, 50 mm, 80 mm, 100 mm; sandblasting time: 5 s, 10 s, 15 s, 30 s, 60 s, 90 s, 120 s, 180 s, 300 s.

[0038] In a specific embodiment, the sandblasting process parameters may be as follows: sandblasting particle size: 60 mesh, 80 mesh, 100 mesh, 120 mesh; sandblasting pressure: 0.2 MPa, 0.3 MPa, 0.4 MPa, 0.5 MPa; sandblasting distance: 30 mm, 50 mm, 80 mm, 100 mm; sandblasting time: 10 s, 15 s, 30 s, 60 s, 90 s.

[0039] The sandblasting process parameters may be as follows: sandblasting particle size: (60 - 120 mesh); sandblasting pressure: (0.2 - 0.5 MPa); sandblasting distance: (30 - 100 mm); sandblasting time: (10 - 90 s).

[0040] Through experimental exploration, it is found that further controlling the sandblasting process parameters within the above range results in better specific surface area and roughness of the pure titanium implant material obtained by sandblasting.

[0041] Cleaning after sandblasting: Place the pure titanium implant material after sandblasting into deionized water and perform ultrasonic cleaning twice.

[0042] The purpose of cleaning after sandblasting is to thoroughly remove the remaining particles. Specifically, the pure titanium implant material that has completed the sandblasting process is immersed in deionized water and ultrasonic cleaning is performed twice, with each time being 300 seconds. The frequency is set at 30 - 50 Hz for the first round and increased to 80 - 100 Hz for the second round.

[0043] Specifically, the ultrasonic cleaning is divided into two times. The frequency of the first ultrasonic cleaning is 30 - 50 Hz and the time is 200 - 400 s. The frequency of the second ultrasonic cleaning is 90 - 110 Hz and the time is 200 - 400 s.

[0044] In some embodiments, the frequency of the first ultrasonic cleaning is 30 - 40 Hz or 40 - 50 Hz In a specific embodiment, the frequency of the first ultrasonic cleaning is 30 Hz, 40 Hz, 50 Hz.

[0045] In some embodiments, the frequency of the second ultrasonic cleaning is 80 - 90 Hz or 90 - 100 Hz.

[0046] In a specific embodiment, the frequency of the second ultrasonic cleaning is 80 Hz, 90 Hz, or 100 Hz.

[0047] The frequency of the first ultrasonic cleaning is 50 Hz and the time is 400 s. The frequency of the second ultrasonic cleaning is 100 Hz and the time is 300 s.

[0048] The present application will be further described in detail below in conjunction with preparation examples, examples, performance detection tests, and the accompanying drawings.

[0049] Preparation Examples 1-9 Preparation Examples 1-9 respectively provide a set of sandblasting parameters.

[0050] The differences between the above preparation examples lie in the combination of sandblasting parameters, as shown in Table 1 below.

[0051] The sandblasting parameters provided by Preparation Examples 1-9 are as follows: Alumina particles of a certain particle size are used to sandblast the surface of pure titanium under a certain pressure, sandblasting distance, and time.

[0052] Table 1 Combinations of sandblasting parameters for pure titanium implant materials provided by Preparation Examples 1-9 Preparation Example Particle Size (mesh) Pressure (MPa) Distance (mm) Time (s) 1 60 0.2 30 30 2 80 0.3 80 10 3 100 0.4 30 60 4 120 0.5 100 90 5 60 0.4 100 15 6 60 0.3 80 60 7 80 0.2 50 90 8 100 0.5 30 30 9 120 0.4 50 15 Examples 1-9 Examples 1-9 respectively provide a sandblasting method for pure titanium implant materials.

[0053] The differences between the above examples lie in that in the sandblasting methods for pure titanium implant materials, the sandblasting parameters are respectively derived from Preparation Examples 1-9.

[0054] The sandblasting methods for pure titanium implant materials provided by Examples 1-9 include the following steps: (1) Cleaning before sandblasting: Prepare according to Preparation Examples 1-9 respectively.

[0055] (2) Sandblasting: Inject alumina particles into the sandblaster, open the air compressor valve, adjust the pressure gauge of the sandblaster, adjust the distance between the pure titanium implant material to be sandblasted and the nozzle, and start sandblasting and timing. The sandblasting time is controlled within 10 - 90 s.

[0056] (3) Post-treatment: Place the sandblasted pure titanium implant material in deionized water, perform the first ultrasonic cleaning at 30 - 50 Hz for 200 - 400 s; perform the second ultrasonic cleaning at 80 - 100 Hz for 100 - 300 s.

[0057] Examples 10-18 Examples 10-18 respectively provide a cleaning method for pure titanium implant materials.

[0058] The difference between the above embodiment and Embodiment 5 is that ultrasonic cleaning is divided into two times. The pure titanium implant material after sandblasting is successively placed in two deionized water tanks for ultrasonic cleaning. The frequencies and times of the two ultrasonic cleanings are shown in Table 2 below.

[0059] Table 2 Frequencies and times of ultrasonic cleaning in the sandblasting methods of Embodiments 10 - 18 Performance detection test The pure titanium implant materials obtained after sandblasting in Embodiments 1 - 9 were detected, and the results are shown in Table 3 below.

[0060] Surface condition: The surface conditions of the pure titanium implant material in Embodiment 5 before and after sandblasting were observed using a metallurgical microscope and an electron microscope respectively; refer to Figure 2 (A), which is the metallurgical microscope image of the untreated pure titanium implant material; refer to Figure 2 (B), which is the metallurgical microscope image of the pure titanium implant material after being treated in Embodiment 5; refer to Figure 3 (A) is the electron microscope image of the untreated pure titanium implant material; (2) Roughness: The roughness values Ra, Rq, and Rz of the untreated pure titanium implant material and the pure titanium implant materials obtained after sandblasting in Embodiments 1 - 9 were detected using a 3D profilometer. Five places were randomly detected and the average value was taken; refer to Figure 4 (A) are the roughness values Ra, Rq, and Rz of the untreated pure titanium implant material; Table 3 Performance detection results of the pure titanium implant materials in Embodiments 1 - 9 Table 4 Detection results of the Al residue content in the cleaning of the pure titanium implant materials after sandblasting in Embodiments 10 - 18 According to the detection results in Table 3, the surface roughness Ra of the pure titanium implant material after being treated by the sandblasting method of the pure titanium implant materials provided in Embodiments 1 - 9 is 1.406 - 2.494 μm; the surface roughnesses of different brands of existing commercial implants vary greatly, and their values are between 0.12 μm and 4.29 μm. The surface of the pure titanium implant prepared by the present invention meets the appropriate roughness requirements for bone bonding. A relatively large roughness on the implant surface can help the implant obtain better initial stability during implantation, thereby promoting the bone bonding process. Therefore, the sandblasting parameters of Embodiment 5 are better.

[0061] From the detection results of Examples 10-18, it can be seen that in Examples 10-18, ultrasonic cleaning was performed twice for Example 5, and the residual Al content on the surface of the pure titanium implant was detected by EDS analysis. The residual Al content on the surface of the pure titanium implant in Example 18 was the lowest. Therefore, it shows that the two-step cleaning method of Example 18 in this application can remove the Al residue on the surface of the pure titanium implant material to the greatest extent. After acid etching treatment, the results show that the residual Al content on the surface of the pure titanium implant in Example 18 is 0.

[0062] Therefore, it shows that in this application, the frequency and time of the two ultrasonic cleanings are further controlled within the following ranges: the frequency of the first ultrasonic cleaning is 30-50 kHz, and the time is 400 s; the frequency of the second ultrasonic cleaning is 80-100 kHz, and the time is 300 s. This can minimize the Al content on the surface of the pure titanium implant material. After verification by the SLA process, the acid etching process can completely remove the Al element from the pure titanium implant material.

[0063] The implementation principle of the sandblasting method for a pure titanium implant material in an embodiment of this application is as follows: in the sandblasting pretreatment step, through multiple ultrasonic cleanings and drying of the pure titanium implant material, impurities on the material surface are effectively removed, ensuring a higher quality of the rough morphology formed during the subsequent sandblasting process. In the sandblasting step, by adjusting key parameters such as alumina particles, sandblasting machine pressure, distance between the nozzle and the material, and sandblasting time, a uniform and rock-like rough morphology suitable for medical implant standards is formed on the pure titanium surface, increasing the specific surface area of the pure titanium implant material, thereby enhancing its biological activity and promoting the bone bonding process. The optimized sandblasting process obtains an ideal surface roughness range that meets the standard requirements of medical implants, provides more surface binding sites for protein adsorption, is conducive to the rapid binding of the postoperative bone tissue and the implant interface, shortens the bone healing cycle, and improves the bone bonding strength. After sandblasting, the pure titanium implant material is placed in deionized water and ultrasonically cleaned twice for 300 s each, which can effectively remove the alumina particles attached to the surface of the sandblasted pure titanium implant material and reduce the influence of residual impurities on the subsequent treatment and implant effect. Specifically, through two ultrasonic cleanings of 300 seconds each, the Al residue on the pure titanium surface can be significantly reduced, optimizing the surface quality of the implant material, thereby improving biocompatibility and bone bonding performance.

[0064] The above are all preferred embodiments of this application. The protection scope of this application is not limited accordingly. Therefore, all equivalent changes made according to the structure, shape, and principle of this application should be covered within the protection scope of this application.

Claims

1. A sandblasting method for a pure titanium implant material, characterized in that: It includes the following steps: Pre-treatment before sandblasting: Use a finished cleaning solution, prepare the cleaning solution according to the instructions of the finished cleaning solution, put the pure titanium implant material to be sandblasted into the prepared cleaning solution, perform ultrasonic cleaning for 20 minutes, and then put the pure titanium implant material to be sandblasted into deionized water for ultrasonic cleaning for 20 minutes; Repeat twice and dry for standby; Sandblasting: Inject alumina particles into the sandblaster, open the air compressor valve, adjust the pressure gauge of the sandblaster, adjust the distance between the pure titanium implant material to be sandblasted and the nozzle, and start sandblasting and timing; Cleaning after sandblasting: Put the pure titanium implant material after sandblasting into deionized water and perform ultrasonic cleaning twice, each time for 300 seconds.

2. The sandblasting method of the pure titanium implant material according to claim 1, characterized in that: For the pre-treatment before sandblasting, the specific steps are: The volume ratio of the pure titanium implant material to the prepared cleaning solution is 1:

15.

3. The sandblasting method of the pure titanium implant material according to claim 2, characterized in that: The ultrasonic frequency in the ultrasonic cleaning during the pre-treatment before sandblasting is 40 - 80 Hz, and the temperature is adjusted to 50 °C.

4. The sandblasting method of the pure titanium implant material according to claim 1, characterized in that: The particle size of the alumina particles during the sandblasting process is 60 - 80 mesh.

5. The sandblasting method of the pure titanium implant material according to claim 4, characterized in that: The pressure of the sandblaster during the sandblasting process is 0.2 - 0.4 MPa.

6. The sandblasting method of the pure titanium implant material according to claim 5, characterized in that: The distance between the pure titanium implant material to be sandblasted and the nozzle during the sandblasting process is 10 - 150 mm.

7. The sandblasting method of the pure titanium implant material according to claim 6, characterized in that: The sandblasting time during the sandblasting process is 15 - 60 s.

8. The sandblasting method of the pure titanium implant material according to claim 1, characterized in that: The ultrasonic cleaning frequency after sandblasting is 30 - 100 Hz, and the time is 100 - 400 s.

9. A pure titanium implant material after sandblasting, obtained by using the sandblasting method for the pure titanium implant material described in any one of claims 1-8, characterized in that, The surface roughness of the pure titanium implant material after sandblasting is 1.05 ≤ Ra ≤ 2.7 μm.

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