Sweat-proof and waterproof physical and biological synergistic sunscreen composition and application thereof

Abstract

The invention relates to a sweat-proof and waterproof physical and biological synergistic sunscreen composition and application thereof. The composition comprises a physical sunscreen agent and a biological active component, the physical sun-screening agent is prepared from zinc oxide, sodium isostearoyl lactylate, PEG-30 (Polyethylene Glycol) dipolyhydroxystearate, talcum powder and polydimethylsiloxane; the bioactive components comprise photolyase, tranexamic acid, 4-methylsalicylic acid and an algae extract. According to the composition provided by the invention, through the synergistic effect of the physical sun-screening agent and the bioactive components, the characteristic that the composition becomes strong when meeting water and becomes strong when meeting light is realized.

Description

Technical Field

[0001] The present invention relates to the technical field of cosmetics, and in particular to a sweat-proof and waterproof physical and biological synergistic sunscreen composition and application thereof. Background Art

[0002] Long-term exposure to ultraviolet rays increases the risk of skin cancer and photoaging. Using sunscreen products can reduce the risk of skin cancer by blocking UVA (long-wave ultraviolet rays, which cause aging) and UVB (medium-wave ultraviolet rays, which cause sunburn).

[0003] CN107854420A discloses a sunscreen cosmetic composition and sunscreen cream and a preparation method thereof. The composition contains ginseng stem cell secretory factor, biotin tripeptide-1, nutrients, ultrafine powder and a matrix. Relative to 100 parts by weight of the matrix, the matrix is composed of the following components: 20-30% lipid, 15-25% emulsifier, 2-3% co-emulsifier, 0.5-1.2% stabilizer, 0.5-1.2% preservative, and the remainder water.

[0004] CN115282073A discloses a sunscreen composition, comprising the following raw materials in parts by weight: 8.5-20 parts of a chemical sunscreen, 4-15 parts of a physical sunscreen, and 0.02-1 part of a plant sunscreen; the chemical sunscreen is selected from one or more of bis-ethylhexyloxyphenol methoxyphenyl triazine, butyl methoxydibenzoylmethane, diethylaminohydroxybenzoyl hexyl benzoate, diethylhexyl butyramidotriazone, ethylhexyl methoxycinnamate, ethylhexyl salicylate, ethylhexyl triazone, homosalate, octocrylene, and phenylbenzimidazole sulfonic acid; the physical sunscreen is selected from one or more of titanium dioxide and zinc oxide; and the plant sunscreen is selected from one or more of wood apple extract, aloe extract, tea extract, scutellaria root extract, lithospermum officinale extract, safflower extract, plantain extract, ligusticum chuanxiong extract, lycopodium extract, cimicifuga extract, chlorella extract, sophora japonica bud extract, and rapeseed extract.

[0005] Traditional sunscreen products primarily rely on physical and chemical sunscreens to block UV rays, but these products suffer from limited effectiveness, insufficient stability, and diminished effectiveness with water or sweating. Furthermore, existing sunscreen products still need improvement in terms of photostability, photoaging resistance, and repair of photodamage. Therefore, developing a highly effective, stable sunscreen product with multiple protective properties is crucial. Summary of the Invention

[0006] To address the above technical issues, the present invention provides a sweat-proof and waterproof, physical-biological synergistic sunscreen composition and its application. The composition provided by the present invention achieves the properties of being stronger in water and even stronger in light through the synergistic effect of a physical sunscreen and a biologically active ingredient.

[0007] To achieve this object, the present invention adopts the following technical solutions:

[0008] In a first aspect, the present invention provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, the composition comprising a physical sunscreen and a biologically active ingredient;

[0009] The physical sunscreens include zinc oxide, sodium isostearyl lactylate, PEG-30 dipolyhydroxystearate, talc, and dimethicone;

[0010] The bioactive ingredients include photorepair enzymes, tranexamic acid, 4-methylsalicylic acid and algae extracts.

[0011] The zinc oxide and talc in the physical sunscreens of this invention provide synergistic sun protection. Sodium isostearyl lactylate, PEG-30 dipolyhydroxystearate, and polydimethylsiloxane are also added to enhance the product's water and sweat resistance. This mixture of physical sunscreens effectively reflects and scatters ultraviolet rays, exhibits thermoelectric and piezoelectric effects, promotes blood circulation in the skin, and enhances the skin's self-repairing ability.

[0012] Among the bioactive ingredients, photorepair enzymes are highly efficient and specific enzymes that repair DNA damage within cells. Derived from the extract of volcanic thermophilic bacteria, they are 95% pure, highly heat-resistant, and stable, capable of reliably repairing photodamage and reversing photoaging. Tranexamic acid has anti-inflammatory properties and inhibits melanin production. 4-Methylsalicylic acid enhances the production of UV wavelength-converting substances. Algae extracts contain cyanobacteria whitening essences, which effectively scavenge free radicals in the body, protecting cell membranes and DNA from oxidative damage and possessing a potent melanin-reducing effect. The rational combination of these ingredients creates a synergistic effect, further enhancing sunscreen performance.

[0013] The composition provided by the present invention has the following characteristics: (1) Stronger when exposed to water: After the product comes into contact with water or sweat, the sun protection effect will not only not weaken, but will be enhanced. This is because the bioactive ingredients can better play their role in a humid environment, and the stability of the physical sunscreen is also improved; (2) Stronger when exposed to light: Under light conditions, bioactive ingredients such as photorepair enzymes can be activated, further enhancing the sun protection effect, while repairing light damage and delaying photoaging; (3) Full-band protection: The product can effectively protect against multiple harmful light rays such as UVA, UVB and blue light, providing all-round skin protection.

[0014] The present invention realizes the ability of waterproofing and sweat-proofing and enhancing the sun protection effect through the synergistic effect of physical sunscreen agents and biologically active ingredients.

[0015] Preferably, the algae extract comprises any one of Spirulina maxima extract, Coralline algae extract or Sargassum microcarpa extract, or a combination of at least two of them.

[0016] Preferably, the composition comprises 2-12 parts by mass of zinc oxide (for example, 2 parts, 4 parts, 6 parts, 8 parts, 10 parts, 12 parts, etc.), 0.5-2 parts of sodium isostearyl lactylate (for example, 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, 0.9 parts, 1.0 parts, 1.5 parts, 2.0 parts, etc.), 0.1-0.5 parts of PEG-30 dipolyhydroxystearate (for example, 0.1 parts, 0.15 parts, 0.2 parts, 0.25 parts, 0.3 parts, 0.35 parts, 0.4 parts, 0.45 parts, 0.5 parts, etc.), 0.05-0.3 parts of talc (for example, 0.05 parts, 0.1 parts, 0.15 parts, 0.2 parts, 0.25 parts, 0.3 parts, etc.), 5-15 parts of polydimethylsiloxane (for example, 5 0.005-0.05 parts (for example, 0.005 parts, 0.01 parts, 0.02 parts, 0.03 parts, 0.04 parts, 0.05 parts, etc.), 0.05-0.1 parts of 4-methylsalicylic acid (for example, 0.05 parts, 0.06 parts, 0.07, 0.08, 0.09, 0.1, etc.), tranexamic acid 0.05-0.1 parts (for example, it can be 0.05, 0.06, 0.07, 0.08, 0.09, 0.1 parts, etc.) and algae extract 0.05-1 parts (for example, it can be 0.05, 0.06, 0.07, 0.08, 0.09, 1 parts, etc.).

[0017] Preferably, the bioactive ingredients also include mullein extract, vitamin B 12 , rutin, dipotassium glycyrrhizate or niacinamide, or a combination of at least two thereof.

[0018] In the present invention, the mullein extract is an ultraviolet wavelength conversion substance, which has the effects of anti-photoaging, anti-oxidation and skin brightening; vitamin B 12 A UV wavelength converter reduces melanin deposition; rutin repairs the barrier, providing anti-aging and photodamage protection; dipotassium glycyrrhizate enhances the function of UV wavelength converters; and niacinamide inhibits pigmentation, improves barrier function, and provides moisturizing properties. Adding these components to the composition further enhances sun protection.

[0019] Preferably, the bioactive ingredients also include mullein extract, vitamin B 12 , rutin, dipotassium glycyrrhizate and niacinamide.

[0020] Preferably, the composition further comprises 0.15-0.25 parts of mullein extract (for example, 0.15 parts, 0.18 parts, 0.2 parts, 0.22 parts, 0.25 parts, etc.), vitamin B 12 0.02-0.08 parts (for example, 0.02 parts, 0.04 parts, 0.06 parts, 0.08 parts, etc.), rutin 0.005-0.025 parts (for example, 0.005 parts, 0.01 parts, 0.015 parts, 0.02 parts, 0.025 parts, etc.), dipotassium glycyrrhizate 0.05-0.1 parts (for example, 0.05 parts, 0.06 parts, 0.07 parts, 0.08 parts, 0.09 parts, 0.1 parts, etc.) and niacinamide 0.05-0.2 parts (for example, 0.05 parts, 0.08 parts, 0.1 parts, 0.12 parts, 0.15 parts, 0.18 parts, 0.2 parts, etc.).

[0021] In a second aspect, the present invention provides a use of the sweat-proof and waterproof physical and biological synergistic sunscreen composition according to the first aspect in cosmetics.

[0022] Preferably, the cosmetics include sunscreen, isolation lotion, foundation or day cream.

[0023] In a third aspect, the present invention provides a sunscreen lotion comprising the sweat-proof and waterproof physical and biological synergistic sunscreen composition of the first aspect, a moisturizer, an emulsifier, a thickening stabilizer, a skin conditioner and water.

[0024] Preferably, the sunscreen lotion comprises, by mass percentage, 7.805-31.05% of the sweat-proof and waterproof physical and biological synergistic sunscreen composition of the first aspect (for example, 7.805%, 8%, 10%, 12%, 15%, 18%, 20%, 22%, 25%, 28%, 30%, 31.05%, etc.), 0.1-10% of a moisturizer (for example, 0.1%, 0.5%, 1%, 2%, 5%, 10%, etc.), 0. 01-10% (for example, it can be 0.01%, 0.05%, 0.1%, 1%, 5%, 10%, etc.), thickening stabilizer 0.1-10% (for example, it can be 0.1%, 1%, 3%, 5%, 7%, 10%, etc.), skin conditioner 0.1-5% (for example, it can be 0.1%, 0.5%, 1%, 2%, 3%, 4%, 5%, etc.) and water 50-90% (for example, it can be 50%, 60%, 70%, 80%, 90%, etc.).

[0025] Preferably, the moisturizing agent comprises any one of glycerin, hyaluronic acid, pentylene glycol or hexylene glycol, or a combination of at least two thereof.

[0026] Preferably, the emulsifier comprises polysorbate.

[0027] Preferably, the thickening stabilizer comprises any one of carbomer, dextran or cellulose, or a combination of at least two thereof.

[0028] Preferably, the skin conditioning agent comprises any one or a combination of at least two of ceramide, lecithin, undecylenoylphenylalanine, magnolia sieboldii extract, hybrid rose flower extract or gardenia fruit extract.

[0029] In a fourth aspect, the present invention provides a method for preparing the sunscreen lotion according to the third aspect, the preparation method comprising the following steps:

[0030] (1) mixing the physical sunscreen, moisturizer, emulsifier, thickening stabilizer, and a portion of water in the sweat-proof and waterproof physical and biological synergistic sunscreen composition of the first aspect, heating and dissolving, and then high-pressure homogenizing to obtain component 1;

[0031] (2) Component 1, a skin conditioner, the biologically active ingredients in the sweat-proof and waterproof physical and biological synergistic sunscreen composition described in the first aspect, and the remaining water are mixed to obtain the sunscreen lotion.

[0032] In this invention, the physical sunscreen is formed into a negatively charged double-layer spherical structure through high pressure and high shear technology. Double-sphere encapsulation prevents aggregation and improves product stability and sunscreen effectiveness. During the high-pressure homogenization process, particle size can be measured using X-ray diffraction, achieving a controlled particle size of approximately 1 μm.

[0033] Preferably, the heating in step (1) is to a temperature of 75-90°C (for example, 75°C, 80°C, 85°C, 90°C, etc.).

[0034] Preferably, the pressure of the high-pressure homogenization in step (1) is 5-15 MPa (for example, 5 MPa, 8 MPa, 10 MPa, 12 MPa, 15 MPa, etc.), and the flow rate is 4-8 L / min (for example, 4 L / min, 5 L / min, 6 L / min, 7 L / min, 8 L / min, etc.).

[0035] Compared with the prior art, the present invention has at least the following beneficial effects:

[0036] (1) Highly effective sun protection: Through the synergistic effect of physical sunscreens and bioactive ingredients, the product can provide a variety of sun protection strengths such as SPF15+++ and SPF30+++ to meet the needs of different users.

[0037] (2) Repair photodamage: Bioactive ingredients such as photorepair enzymes can be activated under light conditions to repair DNA damage in cells, reverse photoaging, and restore skin's radiance.

[0038] (3) Becomes stronger when exposed to water and light: The sun protection effect of the product will be further enhanced after it comes into contact with water or sweat, as well as under light conditions, providing users with more reliable sun protection.

[0039] (4) All-round protection: It not only protects against ultraviolet rays, but also absorbs blue light, providing full-band protection and effectively preventing sunburn, tanning, photoaging and other problems. DETAILED DESCRIPTION

[0040] For the convenience of understanding the present invention, the present invention is given below with examples. It should be understood by those skilled in the art that the examples are only for the purpose of helping to understand the present invention and should not be regarded as specific limitations of the present invention.

[0041] The sources of materials used in the following embodiments and application examples are as follows:

[0042]

[0043]

[0044] The weight percentages of the raw materials mentioned above are calculated based on the actual content of the effective ingredients contained in the commercially available raw materials. The commercially available raw materials may also selectively contain any one or a combination of at least two of solvents, fillers, diluents, stabilizers, pH regulators, antibacterial agents, antioxidants or impurities within the permitted range.

[0045] Other raw materials are common commercial products and will not be described in detail here.

[0046] Example 1

[0047] This embodiment provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which comprises, by weight: 10 parts of zinc oxide, 1.0 part of sodium isostearyl lactylate, 0.3 parts of PEG-30 dipolyhydroxystearate, 0.3 parts of talc, 8 parts of polydimethylsiloxane, 0.005 parts of photorepair enzyme, 0.1 parts of 4-methylsalicylic acid, 0.1 parts of tranexamic acid, 1 part of algae extract (Spirulina maxima extract, coralline algae extract and Sargassum microcarpa extract in a mass ratio of 1:1:1), 0.2 parts of mullein extract, and vitamin B12. 12 0.05 parts, rutin 0.01 parts, dipotassium glycyrrhizate 0.1 parts, niacinamide 0.12 parts.

[0048] Example 2

[0049] This embodiment provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which comprises, by weight: 7.5 parts of zinc oxide, 0.5 parts of sodium isostearyl lactylate, 0.2 parts of PEG-30 dipolyhydroxystearate, 0.2 parts of talc, 5 parts of polydimethylsiloxane, 0.005 parts of photorepair enzyme, 0.05 parts of 4-methylsalicylic acid, 0.07 parts of tranexamic acid, 0.2 parts of coralline algae extract, 0.15 parts of mullein extract, and vitamin B 12 0.02 parts, rutin 0.02 parts, dipotassium glycyrrhizate 0.08 parts, niacinamide 0.2 parts.

[0050] Example 3

[0051] This embodiment provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which comprises, by weight: 3 parts of zinc oxide, 2 parts of sodium isostearyl lactylate, 0.12 parts of PEG-30 dipolyhydroxystearate, 0.05 parts of talc, 12 parts of polydimethylsiloxane, 0.05 parts of photorepair enzyme, 0.05 parts of 4-methylsalicylic acid, 0.05 parts of tranexamic acid, 0.05 parts of micro-labile sargassum extract, 0.25 parts of mullein extract, and vitamin B 12 0.08 parts, 0.05 parts of dipotassium glycyrrhizate, and 0.05 parts of niacinamide.

[0052] Example 4

[0053] This embodiment provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which includes, by weight: 10 parts of zinc oxide, 1.0 part of sodium isostearyl lactylate, 0.3 part of PEG-30 dipolyhydroxystearate, 0.3 part of talc, 8 parts of polydimethylsiloxane, 0.005 part of photorepair enzyme, 0.1 part of 4-methylsalicylic acid, 0.1 part of tranexamic acid, and 1 part of algae extract (Spirulina maxima extract, coralline algae extract, and Sargassum microcarpa extract in a mass ratio of 1:1:1).

[0054] Comparative Example 1

[0055] This comparative example provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which differs from Example 4 only in that it does not contain zinc oxide, and its mass fraction is allocated to talc. Other references refer to Example 4.

[0056] Comparative Example 2

[0057] This comparative example provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which differs from Example 4 only in that it does not contain talc powder, and its mass fraction is allocated to zinc oxide. Other references refer to Example 4.

[0058] Comparative Example 3

[0059] This comparative example provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which differs from Example 4 only in that it does not contain sodium isostearyl lactylate, and its mass fraction is distributed according to the mass ratio of PEG-30 dipolyhydroxystearate and polydimethylsiloxane. Other references refer to Example 4.

[0060] Comparative Example 4

[0061] This comparative example provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which differs from Example 4 only in that it does not contain PEG-30 dipolyhydroxystearate, and its mass fraction is distributed according to the mass ratio of sodium isostearyl lactylate and polydimethylsiloxane. Other references refer to Example 4.

[0062] Comparative Example 5

[0063] This comparative example provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which differs from Example 4 only in that it does not contain polydimethylsiloxane, and its mass fraction is distributed according to the mass ratio of sodium isostearyl lactylate and PEG-30 dipolyhydroxystearate. Other references refer to Example 4.

[0064] Comparative Example 6

[0065] This comparative example provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which differs from Example 4 only in that it does not contain photorepair enzyme, and its mass fraction is distributed according to the mass ratio of algae extract, 4-methylsalicylic acid and tranexamic acid. Other references refer to Example 4.

[0066] Comparative Example 7

[0067] This comparative example provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which differs from Example 4 only in that it does not contain algae extract, and its mass fraction is distributed according to the mass ratio of photorepair enzyme, 4-methylsalicylic acid and tranexamic acid. Other references refer to Example 4.

[0068] Comparative Example 8

[0069] This comparative example provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which differs from Example 4 only in that it does not contain 4-methylsalicylic acid, and its mass fraction is distributed according to the mass ratio of photorepair enzyme, algae extract and tranexamic acid. Other references refer to Example 4.

[0070] Comparative Example 9

[0071] This comparative example provides a sweat-proof and waterproof physical and biological synergistic sunscreen composition, which differs from Example 4 only in that it does not contain tranexamic acid, and its mass fraction is distributed according to the mass ratio of photorepair enzyme, algae extract and 4-methylsalicylic acid. For other reasons, refer to Example 4.

[0072] Application Example 1

[0073] This application example provides a sunscreen lotion, which contains the composition provided in Example 1 and includes the following components by mass percentage:

[0074]

[0075]

[0076] The preparation method comprises the following steps:

[0077] (1) Add the components of component A to the emulsifier in the above proportions, heat to 80°C, stir at 35 rpm for 30 min, cool to 55°C, and homogenize under high pressure at a pressure of 15 MPa and a flow rate of 6 L / min.

[0078] (2) Add the components of component B in sequence, stir at 55°C and 35 rpm for 10 min, add to phase A, stir evenly, and cool to 45°C;

[0079] (3) Components C and D were mixed evenly and added to the above solution, and stirred at 35 rpm for 15 minutes until the material was uniform, thereby preparing a sunscreen product.

[0080] Application Examples 2-4

[0081] Application Examples 2-4 respectively provide a sunscreen lotion, which differs from Application Example 1 only in that the composition provided in Example 1 is replaced by the compositions provided in Examples 2-4, respectively, while keeping the overall addition amount of the composition unchanged. For other matters, refer to Application Example 1.

[0082] Comparative Application Examples 1-9

[0083] Comparative Application Examples 1-9 respectively provide a sunscreen lotion, which differs from Application Example 1 only in that the composition provided in Example 1 is replaced by the compositions provided in Comparative Examples 1-9, respectively, while keeping the overall addition amount of the composition unchanged. For other matters, refer to Application Example 1.

[0084] Application Example 5

[0085] This application example provides an isolation cream, which contains the composition provided in Example 2 and includes the following components by mass percentage:

[0086]

[0087]

[0088] The preparation method comprises the following steps:

[0089] (1) Add the components of component A to the emulsifier in the above proportions, heat to 85°C, stir at 35 rpm for 30 min, cool to 60°C, and homogenize under high pressure at a pressure of 10 MPa and a flow rate of 4 L / min;

[0090] (2) Add the components of component B in sequence, stir at 60°C and 35 rpm for 10 min, add to phase A, stir evenly, and cool to 50°C;

[0091] (3) Component C and component D were mixed evenly and added to the above solution, and stirred at 35 rpm for 20 min until the material was uniform, to obtain an isolating milk product.

[0092] Application Example 6

[0093] This application example provides a liquid foundation, which contains the composition provided in Example 3, and includes the following components by mass percentage:

[0094]

[0095]

[0096] The preparation method comprises the following steps:

[0097] (1) Add the components of component A to the emulsifier in the above proportions, heat to 85°C, stir at 35 rpm for 30 min, cool to 60°C, and homogenize under high pressure at a pressure of 5 MPa and a flow rate of 8 L / min;

[0098] (2) Add the components of component B in sequence, stir at 60°C and 35 rpm for 10 min, add to phase A, stir evenly, and cool to 50°C;

[0099] (3) Components C and D were mixed evenly and added to the above solution, and stirred at 35 rpm for 20 min until the material was uniform, thereby preparing a liquid foundation product.

[0100] Test Example 1

[0101] Sunscreen effect evaluation

[0102] The sun protection index of the samples was determined in accordance with the Cosmetic Safety Technical Specifications (2015) "Method for Determination of Cosmetic Sun Protection Index", and 12 volunteers were recruited for each sample for testing.

[0103]

[0104] SPF, Sun protection factor, is the ratio of the MED required to cause erythema on skin protected by sunscreen cosmetics to the MED required to cause erythema on unprotected skin.

[0105] MED, Minimal erythema dose: The lowest dose of UV radiation required to cause a clearly visible erythema on the skin, covering most of the irradiated area (J / m 2 ) or minimum time (seconds).

[0106] The samples provided in the corresponding use cases 1-6 and comparative application examples 1-9 were tested, and the test results are shown in Table 1.

[0107] Table 1

[0108]

[0109]

[0110] The test results show that:

[0111] (1) It can be seen from Application Examples 1 to 6 that the present invention can achieve a better sun protection effect by compounding physical sunscreen agents and biologically active ingredients, and the components have a synergistic effect.

[0112] (2) By comparing Application Example 4 with Comparative Application Examples 1-9, it can be seen that in the composition provided by the present invention, zinc oxide and talc in the physical sunscreen have a synergistic effect, sodium isostearyl lactylate, PEG-30 dipolyhydroxystearate and polydimethylsiloxane have a synergistic effect, and photorepair enzyme, tranexamic acid, 4-methylsalicylic acid and algae extract in the biologically active ingredients have a synergistic effect. By rationally compounding the physical sunscreen and the biologically active ingredients, the sun protection effect of the product is jointly improved.

[0113] Test Example 1

[0114] Waterproof and sweat-proof effect evaluation

[0115] (1) The waterproof performance of the samples was tested according to the Cosmetics Safety Technical Specifications (2015) Cosmetics Waterproof Performance Determination Method. Twelve volunteers were recruited for each sample to conduct the test, and the ratio of the post-bath SPF value to the sample SPF value was calculated.

[0116] (2) Prepare artificial sweat solution, each liter of which contains 2g sodium chloride, 50mg sodium pyruvate, 10mg anhydrous disodium hydrogen phosphate, 50mg calcium sulfate dihydrate, 170mg potassium bicarbonate, 20mg D-glucose, 50mg glycine, 25mg leucine, 80mg serine, 40mg alanine, 50mg arginine, 100mg histidine, 20mg valine, 15mg isoleucine, 35mg lysine hydrochloride, 15mg phenylalanine, 20mg tyrosine, 5mg glutamine, 25mg aspartic acid, 35mg glutamic acid, 8mg proline, 50mg ornithine hydrochloride, 50mg citrulline, 20mg tryptophan, 10mg asparagine, 35mg threonine, 5mg creatinine, 0.5g lactic acid (88%), and 0.5g urea. According to the Cosmetic Safety Technical Specifications (2015), the anti-perspiration performance of the cosmetics water resistance test samples was tested, and 12 volunteers were recruited for each sample. After applying sunscreen to the test area, rinse it with artificial sweat at a low speed spray for 20 minutes, rest for 20 minutes, and then rinse it with sweat for 20 minutes. Test the SPF value and calculate the ratio of the SPF value after sweat rinse to the SPF value of the sample.

[0117] The samples provided in the corresponding use cases 1-6 and comparative application examples 1-9 were tested, and the test results are shown in Table 2.

[0118] Table 2

[0119]

[0120] The test results show that:

[0121] (1) It can be seen from Application Examples 1 to 6 that the composition provided by the present invention has excellent water and sweat resistance, and can maintain good sun protection performance even when exposed to water or sweating.

[0122] (2) By comparing Application Example 4 with Comparative Application Examples 1-9, it can be seen that in the composition provided by the present invention, zinc oxide and talc in the physical sunscreen agent have a synergistic effect, sodium isostearyl lactylate, PEG-30 dipolyhydroxystearate and polydimethylsiloxane have a synergistic effect, and photorepair enzyme, tranexamic acid, 4-methylsalicylic acid and algae extract in the biologically active ingredients have a synergistic effect, which effectively improves the waterproof and sweat-proof properties of the composition.

[0123] The applicant declares that the above is only a specific embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Those skilled in the art should understand that any changes or substitutions that can be easily thought of by those skilled in the art within the technical scope disclosed by the present invention fall within the scope of protection and disclosure of the present invention.

Claims

1. A sweat-proof and waterproof physical and biological synergistic sunscreen composition, characterized in that: The composition includes a physical sunscreen and a biologically active ingredient; The physical sunscreens include zinc oxide, sodium isostearyl lactylate, PEG-30 dipolyhydroxystearate, talc, and dimethicone; The bioactive ingredients include photorepair enzymes, tranexamic acid, 4-methylsalicylic acid and algae extracts.

2. The composition according to claim 1, characterized in that The algae extract comprises any one of Spirulina maxima extract, Coralline algae extract or Sargassum microcarpa extract, or a combination of at least two of them.

3. The composition according to claim 1 or 2, characterized in that The composition comprises, by mass, 2-12 parts of zinc oxide, 0.5-2 parts of sodium isostearyl lactylate, 0.1-0.5 parts of PEG-30 dipolyhydroxystearate, 0.05-0.3 parts of talc, 5-15 parts of polydimethylsiloxane, 0.005-0.05 parts of photorepair enzyme, 0.05-0.1 parts of 4-methylsalicylic acid, 0.05-0.1 parts of tranexamic acid and 0.05-1 parts of algae extract.

4. The composition according to any one of claims 1 to 3, characterized in that The biologically active ingredients also include mullein extract, vitamin B 12 , rutin, dipotassium glycyrrhizate or niacinamide, or a combination of at least two thereof; Preferably, the bioactive ingredients also include mullein extract, vitamin B 12 , a combination of rutin, dipotassium glycyrrhizate, and niacinamide; Preferably, the composition further comprises 0.15-0.25 parts of mullein extract, vitamin B 12 0.02-0.08 parts, rutin 0.005-0.025 parts, dipotassium glycyrrhizate 0.05-0.1 parts and niacinamide 0.05-0.2 parts.

5. Use of the sweat-proof and waterproof physical and biological synergistic sunscreen composition according to any one of claims 1 to 4 in cosmetics.

6. The use according to claim 5, characterized in that The cosmetics include sunscreen lotion, isolation lotion, foundation liquid or day cream.

7. A sunscreen lotion, characterized in that: The sunscreen lotion comprises the sweat-proof and waterproof physical and biological synergistic sunscreen composition according to any one of claims 1 to 4, a moisturizer, an emulsifier, a thickening stabilizer, a skin conditioner and water.

8. The sunscreen lotion according to claim 7, characterized in that The sunscreen lotion comprises, by mass percentage, 7.805-31.05% of the sweat-proof and waterproof physical and biological synergistic sunscreen composition according to any one of claims 1 to 4, 0.1-10% of a moisturizer, 0.01-10% of an emulsifier, 0.1-10% of a thickening stabilizer, 0.1-5% of a skin conditioner, and 50-90% of water; Preferably, the moisturizing agent comprises any one of glycerin, hyaluronic acid, pentylene glycol or hexylene glycol, or a combination of at least two thereof; Preferably, the emulsifier comprises polysorbate; Preferably, the thickening stabilizer comprises any one or a combination of at least two of carbomer, dextran or cellulose; Preferably, the skin conditioning agent comprises any one or a combination of at least two of ceramide, lecithin, undecylenoylphenylalanine, magnolia sieboldii extract, hybrid rose flower extract or gardenia fruit extract.

9. A method for preparing the sunscreen lotion according to claim 7 or 8, characterized in that: The preparation method comprises the following steps: (1) mixing the physical sunscreen, moisturizer, emulsifier, thickening stabilizer and a portion of water in the sweat-proof and waterproof physical and biological synergistic sunscreen composition according to any one of claims 1 to 4, heating and dissolving, and then high-pressure homogenizing to obtain component 1; (2) Component 1, a skin conditioner, the biologically active ingredients in the sweat-proof and waterproof physical and biological synergistic sunscreen composition according to any one of claims 1 to 4, and the remaining water are mixed to obtain the sunscreen lotion.

10. The preparation method according to claim 9, characterized in that The heating in step (1) is to a temperature of 75-90° C.; Preferably, the pressure of the high-pressure homogenization in step (1) is 5-15 MPa, and the flow rate is 4-8 L / min.

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