Multi-wavelength multi-channel blood coagulation detection device

Abstract

The invention provides a multi-wavelength multi-channel blood coagulation detection device which comprises a multi-wavelength light source assembly used for providing detection light of multiple wavelengths, and the multi-wavelength light source assembly is connected with the light input end of a multi-channel detection assembly through the output end of an optical fiber beam splitter; the multi-channel detection assembly is configured to receive multi-wavelength transmission light signals through a transmission turbidimetric method and generate a blood coagulation reaction curve based on photoelectric conversion and algorithm processing, and a reagent strip base of the multi-channel detection assembly is mechanically connected with a reagent sliding table of the reagent strip movement assembly; accurate positioning and synchronous conveying of the reagent strip in detection of a solidification method, a chromophoric substrate method and an immunoturbidimetry are realized; and the reagent strip movement assembly is used for driving automatic positioning and replacement of the reagent strip, and a stepping motor of the reagent strip movement assembly drives a reagent sliding table to move along a linear guide rail through a synchronous belt and works cooperatively with a detection mounting block of the multi-channel detection assembly, so that a light path is accurately aligned with a sample area in the detection process. Interference factors such as jaundice, hemolysis and lipemia in a blood sample are eliminated through multi-wavelength cooperative detection, meanwhile, multi-item parallel detection is achieved, and the detection efficiency and accuracy are remarkably improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical detection equipment, in particular to a multi-wavelength multi-channel device for coagulation function detection. Background Art

[0002] Coagulation testing is an important part of clinical diagnosis, especially in the monitoring of cardiovascular diseases, hemophilia and anticoagulant drugs. Traditional coagulation testing methodologies include magnetic bead method and optical method, among which optical method occupies the mainstream of the market. Compared with the magnetic bead method, the optical method principle has the advantages of high sensitivity, simple instrument structure and easy automation, but its disadvantages are that it cannot accurately measure samples with lipemia, jaundice and hemolysis, and cannot measure samples with severe interference. Especially when using a single wavelength light source, it is easy to cause deviations in test results. In addition, existing equipment usually only supports single sample or single item testing, and cannot realize the combined detection of multiple coagulation items in one test according to clinical needs. Therefore, it is difficult to meet the testing needs of emergency or special clinical samples, and the detection efficiency is low.

[0003] In recent years, with the diversification of clinical needs, coagulation testing has expanded from the traditional four coagulation parameters to include new indicators such as DD dimer, anti-factor Xa, and antithrombin (AT). However, traditional equipment, limited by its structure and detection principles, struggles to simultaneously detect multiple parameters. Therefore, a new coagulation testing device with a single channel that can combine multi-wavelength technology, enabling simultaneous detection of multiple parameters and integrating multiple channels into a single device is urgently needed to address the shortcomings of existing technologies. Summary of the Invention

[0004] The embodiments of the present application provide a multi-wavelength, multi-channel coagulation detection device, the purpose of which is to eliminate interference through a multi-wavelength light source, improve efficiency through a multi-channel design, and ensure detection accuracy through intelligent motion control.

[0005] In order to solve the above technical problems, the technical solution proposed in this application is: A multi-wavelength multi-channel coagulation detection device, comprising: A multi-wavelength light source assembly, for providing detection light of multiple wavelengths, wherein the multi-wavelength light source assembly is connected to the light input end of the multi-channel detection assembly via the output end of the optical fiber beam splitter; A multi-channel detection assembly configured to receive multi-wavelength transmitted light signals through turbidimetry and generate a coagulation reaction curve based on photoelectric conversion and algorithm processing. The reagent strip base of the multi-channel detection assembly is mechanically connected to the reagent slide of the reagent strip motion assembly to achieve precise positioning and synchronous transportation of the reagent strip in coagulation, chromogenic substrate and immunoturbidimetric assays; The reagent strip motion assembly is used to drive the automatic positioning and replacement of the reagent strip. The stepper motor of the reagent strip motion assembly drives the reagent slide along the linear guide through a synchronous belt, and works in conjunction with the detection mounting block of the multi-channel detection assembly to ensure that the optical path and the sample area are accurately aligned during the detection process.

[0006] Furthermore, the multi-wavelength light source assembly includes at least five LED light sources with different central wavelengths, and the wavelengths of the LED light sources are 340 nm, 405 nm, 575 nm, 660 nm and 800 nm respectively.

[0007] Furthermore, the LED light sources are sequentially lit with a period of 20 ms, and the light is evenly distributed to each detection channel of the multi-channel detection component through the optical fiber combiner and the beam splitter.

[0008] Furthermore, the multi-channel detection assembly includes a beam splitter mounting block, a detection mounting block and a photoelectric detection circuit, wherein: The beam splitter mounting block fixes the output end of the optical fiber beam splitter; The detection mounting block integrates a condenser lens and a photoelectric receiver, which is used to focus the split light onto the sample area of ​​the reagent strip and collect the transmitted light intensity signal in real time; The photoelectric detection circuit is electrically connected to the photoelectric receiver and is used to generate a coagulation reaction curve.

[0009] Furthermore, the reagent strip base and the reagent slide of the reagent strip movement assembly are fixedly connected to form a non-detachable bearing structure. The reagent strip is positioned on the surface of the reagent slide by an openable and closable reagent strip pressing block. When the stepper motor drives the reagent slide to move to the outer preparation position, the reagent strip can be manually taken and placed; when the reagent slide is reset to the inner working position, the reagent strip pressing block presses the reagent strip film through elastic pre-tightening force to prevent the reagent strip from being displaced when the sample needle punctures and takes liquid.

[0010] Furthermore, the reagent strip movement assembly includes a synchronous belt, a synchronous belt fixing block, a driving wheel, a stepping motor, a zero position sensor and a zero position plate, wherein: The synchronous belt is fixedly connected to the drag block via a synchronous belt fixing block; The stepper motor drives the driving wheel to drive the synchronous belt, so that the reagent slide moves along the linear guide rail; The zero position sensor cooperates with the zero position piece to calibrate the initial position of the reagent slide.

[0011] Furthermore, a limit baffle is provided on the reagent slide to limit the movement range of the slide and cooperate with the zero position sensor to ensure positioning accuracy.

[0012] Furthermore, the multi-wavelength light source assembly further includes a heat sink, which is in direct contact with the LED light source and dissipates heat through a heat-conducting material to maintain a stable operating temperature of the light source.

[0013] Furthermore, the device supports simultaneous detection of prothrombin time, activated partial thromboplastin time, and fibrinogen, and each detection channel operates independently without interfering with each other.

[0014] Furthermore, the dichroic mirror in the multi-wavelength light source assembly selectively reflects or transmits light according to wavelength, specifically: The 340nm wavelength light is reflected by the first dichroic mirror to the fiber combiner; The 405nm wavelength light is reflected by the second dichroic mirror and then passes through the first dichroic mirror to the fiber combiner; The remaining wavelengths of light are separated and synthesized in turn through subsequent dichroic mirrors.

[0015] Furthermore, the zero position sensor of the reagent strip motion assembly interacts with the zero position plate to achieve mechanical reset positioning, and the limit block provided at the same time is used for physical calibration of the detection position of the reagent slide; the photoelectric detection circuit of the multi-channel detection assembly is controlled based on the experimental process time program, automatically starts light intensity signal acquisition in the predetermined detection time window, and forms an asynchronous control relationship with the displacement movement of the reagent slide, wherein: The zero position sensor and the zero position piece work together to determine the initial coordinate origin; The light intensity signal acquisition cycle is independently controlled by the preset reaction time parameters of the coagulation test item. When the reagent slide moves to the detection area, the photoelectric detection circuit automatically performs the collection and transmission of the transmitted light intensity data based on the time trigger mechanism.

[0016] Furthermore, the output end of the optical fiber beam splitter is connected to the optical input end of the multi-channel detection component via an adjustable optical fiber connector.

[0017] Furthermore, the stepping motor of the reagent strip movement assembly drives the reagent slide to move along the linear guide rail via a synchronous belt, which means: A driving wheel is installed at the shaft end of the stepper motor of the reagent strip movement assembly, and a transmission pair is formed with the follower wheel installed on the rear side of the right side plate of the movement through a synchronous belt. The synchronous belt is rigidly connected to the drag block through a synchronous belt pressure block. When the stepper motor rotates, it is converted into linear motion through the driving wheel-synchronous belt transmission pair, driving the reagent slide to make precise displacement along the linear guide rail.

[0018] Compared with the existing technology, the multi-wavelength multi-channel coagulation detection device of the present invention has achieved the following beneficial technical effects: High precision: Multi-wavelength collaborative detection can distinguish the light absorption characteristics of interfering substances such as bilirubin and lipids, reducing errors.

[0019] High efficiency: Multi-channel parallel detection supports the simultaneous completion of multiple indicators such as PT, APTT, FIB, etc., shortening the detection cycle. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following is a brief introduction to the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0021] Figure 1 This is a schematic diagram of the overall structure of a multi-wavelength multi-channel coagulation detection device of this application.

[0022] Figure 2 This is a schematic diagram of the overall structure of a multi-wavelength multi-channel coagulation detection device from another angle of the present application.

[0023] Figure 3 This is a schematic diagram of the optical path of a multi-wavelength light source assembly of a multi-wavelength multi-channel coagulation detection device of the present application.

[0024] Figure 4 for Figure 3 Schematic side section of .

[0025] Figure 5 This is a three-dimensional schematic diagram of a multi-channel detection component of a multi-wavelength multi-channel coagulation detection device of the present application; Figure 6 for Figure 5 Schematic cross-section of .

[0026] Figure 7 This is a schematic diagram of the reagent strip movement component of a multi-wavelength, multi-channel coagulation detection device of the present application.

[0027] Figure 8 for Figure 7 Exploded diagram of the reagent strip motion assembly. Among them, the multi-wavelength light source assembly 100; the multi-channel detection assembly 200; the reagent strip movement assembly 300; the LED light source 101; the focusing lens 102; the dichroic mirror 105; the optical fiber combiner 106; the optical fiber beam splitter 107; the LED control circuit 103; the heat sink 104; the beam splitter mounting block 201; the detection mounting block 202; the reagent strip pressing block 203; the reagent strip 204; the reagent strip base 205; the focusing lens 206; the PD detection circuit 207; the moving left plate 301; the linear guide 302; the reagent slide 303; the slide cover 304; the rear base 305; the moving right plate 306; the follower wheel 307; the synchronous belt 308; the synchronous belt fixing block 309; the driving wheel 310; the stepping motor 311; the front base 312; the limit baffle 313; the drag block 314; the zero position sensor 315; and the zero position plate 316 DETAILED DESCRIPTION To make the objectives, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts shall fall within the scope of protection of the present invention.

[0028] Through the synergistic effect of multi-wavelength light source components, multi-channel detection components and reagent strip movement components, the device can effectively eliminate interfering factors such as jaundice, hemolysis, and lipemia in blood samples, while realizing parallel detection of multiple items, significantly improving detection efficiency and accuracy.

[0029] like Figure 1-8 As shown, a multi-wavelength multi-channel coagulation detection device according to an embodiment of the present application includes: The multi-wavelength light source assembly 100 is used to provide detection light of multiple wavelengths. The multi-wavelength light source assembly 100 is connected to the light input end of the multi-channel detection assembly 200 through the output end of the optical fiber beam splitter 107; The multi-channel detection assembly 200 is used to receive the transmitted light signal and generate a coagulation reaction curve. The reagent strip base 205 of the multi-channel detection assembly 200 is mechanically connected to the reagent slide 303 of the reagent strip movement assembly 300 to achieve positioning and transportation of the reagent strip 204; The reagent strip motion assembly 300 is used to drive the automatic positioning and replacement of the reagent strip 204. The stepper motor 311 of the reagent strip motion assembly 300 drives the reagent slide 303 to move along the linear guide rail 302 through the synchronous belt 308, and works in conjunction with the detection mounting block 202 of the multi-channel detection assembly 200 to ensure that the optical path and the sample area are accurately aligned during the detection process.

[0030] In the present application, the multi-wavelength light source assembly 100 is composed of an LED light source 101 , a focusing lens 102 , a dichroic mirror 105 , a fiber combiner 106 and a beam splitter 107 .

[0031] The LED light source 101 includes five wavelengths: 340nm, 405nm, 575nm, 660nm, and 800nm, which are sequentially lit with a cycle of 20ms.

[0032] The optical path design of this component is as follows: the light emitted by each LED light source 101 is focused by the focusing lens 102, and then selectively reflected or transmitted by the dichroic mirror 105 according to the wavelength. For example, 340nm light is reflected, and 405nm light is reflected and then transmitted. Finally, the multi-wavelength light is synthesized by the fiber optic combiner 106 and evenly distributed to each detection channel through the fiber optic splitter 107.

[0033] Heat dissipation and stability: The heat sink 104 is in direct contact with the LED light source 101 and conducts heat through the thermal conductive material to ensure long-term stable operation of the light source.

[0034] The connection relationship between the various components is as follows: LED light source 101 is coaxially mounted with focusing lens 102, and dichroic mirror 105 is located behind the lens to reflect light of a specific wavelength to fiber combiner 106. The output end of fiber combiner 106 is connected to beam splitter 107 via an adjustable fiber connector.

[0035] In the present application, the multi-channel detection assembly 200 includes a beam splitter mounting block 201 , a detection mounting block 202 , a reagent strip pressing block 203 and a photoelectric detection circuit 207 .

[0036] The optical signal collection method is as follows: the split multi-wavelength light is focused onto the sample area of ​​the reagent strip 204 by the focusing lens 206 , and the photoelectric receiver on the opposite side collects the transmitted light intensity signal in real time, and generates a coagulation reaction curve through the PD detection circuit 207 .

[0037] The reagent strip movement method is as follows: the stepping motor 311 of the reagent strip movement assembly 300 drives the reagent slide 303 to move along the linear guide rail 302 via the synchronous belt 308: A driving wheel is installed at the shaft end of the stepper motor 311 of the reagent strip movement assembly 300, and a transmission pair is formed with the follower wheel installed on the rear side of the right side plate of the movement through a synchronous belt 308. The synchronous belt 308 is rigidly connected to the drag block through the synchronous belt pressure block. When the stepper motor 311 rotates, it is converted into linear motion through the driving wheel-synchronous belt transmission pair, driving the reagent slide 303 to make precise displacement along the linear guide rail.

[0038] The connection relationship between the various components is as follows: the beam splitter mounting block 201 fixes the output end of the optical fiber beam splitter 107 to ensure stable transmission of the optical path. The detection mounting block 202 integrates the focusing lens 206 and the photoelectric receiver to ensure that the optical path is accurately aligned with the sample area.

[0039] In the present application, the reagent strip moving assembly 300 includes a stepping motor 311 , a synchronous belt 308 , a reagent slide 303 and a limit sensor 315 .

[0040] The motion control principle is as follows: the stepping motor 311 drives the driving wheel 310 to drive the synchronous belt 308, so that the reagent slide 303 moves along the linear guide 302. The synchronous belt 308 is fixedly connected to the drag block 314 through the synchronous belt fixing block 309 to ensure the reliability of motion transmission.

[0041] The positioning calibration method is as follows: the zero position sensor 315 cooperates with the zero position piece 316 to calibrate the initial position of the slide; the limit baffle 313 limits the movement range of the slide to ensure positioning accuracy.

[0042] The collaborative working logic is as follows: the zero position sensor 315 of the reagent strip motion assembly 300 interacts with the zero position plate to achieve mechanical reset positioning, and the limit block 316 is provided for physical calibration of the detection position of the reagent slide 303; the photoelectric detection circuit 207 of the multi-channel detection assembly 200 automatically starts light intensity signal acquisition in a predetermined detection time window based on the experimental process time program control, and forms an asynchronous control relationship with the displacement movement of the reagent slide 303, wherein: The zero position sensor 315 cooperates with the zero position piece to determine the initial coordinate origin; The light intensity signal acquisition cycle is independently controlled by the preset reaction time parameters of the coagulation test item. When the reagent slide 303 moves to the detection area, the photoelectric detection circuit 207 automatically performs the collection and transmission of the transmitted light intensity data according to the time trigger mechanism.

[0043] The following is a detailed introduction to the operation process: 1. Light source startup and light path synthesis After the device is powered on, the multi-wavelength light source assembly 100 begins operation. The LED light source 101 includes five different wavelengths (340nm, 405nm, 575nm, 660nm, and 800nm), each of which is illuminated sequentially in a 20ms cycle. For example, the 340nm light source is activated first. The ultraviolet light it emits is collimated into a parallel beam by the focusing lens 102 and then irradiated by the first dichroic mirror 105. This dichroic mirror is designed to reflect the 340nm light and transmit light of other wavelengths. The reflected 340nm light is then directed to the input of the fiber combiner 106. Next, the 405nm light source is activated. Its ultraviolet light is reflected by the second dichroic mirror and then passes through the first dichroic mirror 105 to the fiber combiner 106. This process repeats itself, and the five wavelengths are ultimately combined into a composite light path in the fiber combiner 106.

[0044] The synthesized light is evenly distributed to the six detection channels via a fiber optic beam splitter 107. The output of beam splitter 107 interfaces with multi-channel detection assembly 200 via an adjustable fiber optic connector, ensuring consistent light intensity across each channel. Simultaneously, LED control circuit 103 monitors the light source temperature in real time and quickly dissipates heat through heat sink 104 to prevent wavelength drift.

[0045] 2. Reagent Strip Loading and Positioning The operator inserts the reagent strip 204 pre-filled with the blood sample into the reagent strip base 205. The base 205 is mechanically connected to the reagent slide 303 through a dovetail groove structure to ensure that it is in a stable position when the slide moves. The reagent strip base 205 and the reagent slide 303 of the reagent strip movement assembly 300 are fixedly connected to form a non-detachable bearing structure. The reagent strip 204 is positioned on the surface of the reagent slide 303 by the openable and closable reagent strip pressing block 203. When the stepping motor 311 drives the reagent slide 303 to move to the outer preparation position, the reagent strip 204 can be manually taken in and put in; when the reagent slide 303 is reset to the inner working position, the reagent strip pressing block 203 presses the reagent strip coating through an elastic pre-tightening force to prevent the reagent strip from being displaced when the sample needle punctures and takes liquid.

[0046] At this moment, the reagent strip motion assembly 300 starts the initialization process. Stepper motor 311 drives driving wheel 310 to rotate, drives synchronous belt 308 to move. Synchronous belt 308 is connected with dragging block 314 by synchronous belt fixing block 309, and dragging block 314 drives reagent slide 303 to slide along linear guide 302. During the slide movement, zero position sensor 315 continuously detects the position signal of zero position sheet 316. When slide 303 retreats to the initial position, zero position sensor 315 triggers system ready signal, and detection circuit enters standby state.

[0047] 3. Detection Signal Acquisition and Processing Upon receiving the ready signal, stepper motor 311 drives reagent slide 303 to the detection position. Slide 303 slides smoothly along linear guide rail 302, with stopper 313 limiting its range of motion, ensuring that the sample area is precisely aligned with the optical path. Multi-wavelength light is emitted from the output of beam splitter 107 and focused by condenser lens 206 onto the sample area of ​​reagent strip 204. The transmitted light intensity is collected in real time by a photoelectric receiver on the opposite side and converted into an electrical signal by PD detection circuit 207.

[0048] The PD detection circuit 207 uploads the light intensity-time data to the analysis system. The system uses a multi-wavelength data fitting algorithm, for example: The rate of fibrinogen polymerization was detected using 340 nm light; Eliminate the interference of lipid and blood turbidity by 575nm light; The background noise was corrected using 800 nm light as the reference wavelength.

[0049] Finally, the system generates a corrected coagulation curve and outputs parameters such as PT, APTT, and FIB.

[0050] 4. Sample Change and Cycle Testing After the test is complete, stepper motor 311 reverses, driving reagent slide 303 back to its initial position. The reagent strip clamp 203 automatically releases, and the operator removes the tested reagent strip 204 and inserts a new sample to initiate the next round of testing. To switch test items, the light source wavelength combination and data algorithm can be adjusted through the control interface without replacing hardware modules.

[0051] 5. Collaboration details of key components Light path stability is ensured: the fiber combiner 106 and the beam splitter 107 are fixed by the beam splitter mounting block 201 to prevent optical path deviation caused by vibration; the detection mounting block 202 integrates the focusing lens 206 and the photoelectric receiver to ensure that the light spot accurately covers the sample area.

[0052] Motion control accuracy: The combination of the linear guide 302 and the synchronous belt 308 achieves a positioning accuracy of ±0.05mm; the zero position sensor 315 and the limit baffle 313 are double-calibrated to prevent cumulative errors.

[0053] Heat dissipation and life optimization: The heat sink 104 is made of copper-aluminum composite material; the LED control circuit 103 dynamically adjusts the driving current according to the temperature to extend the life of the light source.

[0054] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the various embodiments of the present invention.

Claims

1. A multi-wavelength multi-channel coagulation detection device, characterized in that: include: A multi-wavelength light source assembly (100) is used to provide detection light of multiple wavelengths, wherein the multi-wavelength light source assembly (100) is connected to the light input end of the multi-channel detection assembly (200) via the output end of the optical fiber beam splitter (107); A multi-channel detection component (200) is configured to receive multi-wavelength transmission light signals through transmission turbidimetry and generate a coagulation reaction curve based on photoelectric conversion and algorithm processing. The reagent strip base (205) of the multi-channel detection component (200) is mechanically connected to the reagent slide (303) of the reagent strip movement component (300) to achieve precise positioning and synchronous transportation of the reagent strip (204) in coagulation method, chromogenic substrate method and immunoturbidimetry detection; The reagent strip motion assembly (300) is used to drive the automatic positioning and replacement of the reagent strip (204). The stepper motor (311) of the reagent strip motion assembly (300) drives the reagent slide (303) to move along the linear guide rail (302) through the synchronous belt (308), and cooperates with the detection mounting block (202) of the multi-channel detection assembly (200) to ensure that the optical path and the sample area are accurately aligned during the detection process.

2. The device according to claim 1, characterized in that The multi-wavelength light source assembly (100) comprises at least five LED light sources (101) with different central wavelengths, and the wavelengths of the LED light sources (101) are respectively 340 nm, 405 nm, 575 nm, 660 nm and 800 nm.

3. The device according to claim 2, characterized in that The LED light sources (101) are sequentially lit with a period of 20 ms, and the light is evenly distributed to each detection channel of the multi-channel detection component (200) through the optical fiber combiner (106) and the beam splitter (107).

4. The device according to claim 1, characterized in that The multi-channel detection assembly (200) comprises a beam splitter mounting block (201), a detection mounting block (202), and a photoelectric detection circuit (207), wherein: The beam splitter mounting block (201) fixes the output end of the optical fiber beam splitter (107); The detection mounting block (202) integrates a condenser lens (206) and a photoelectric receiver, and is used to focus the split light onto the sample area of ​​the reagent strip (204) and collect the transmitted light intensity signal in real time; The photoelectric detection circuit (207) is electrically connected to the photoelectric receiver and is used to generate a coagulation reaction curve.

5. The device according to claim 4, characterized in that The reagent strip base (205) and the reagent slide (303) of the reagent strip motion assembly (300) are fixedly connected to form a non-detachable bearing structure. The reagent strip (204) is positioned on the surface of the reagent slide (303) by means of an openable and closable reagent strip pressing block (203). When the stepping motor (311) drives the reagent slide (303) to move to the outer preparation position, the reagent strip (204) can be manually taken in and put out. When the reagent slide (303) is reset to the inner working position, the reagent strip pressing block (203) presses the reagent strip coating with an elastic pre-tightening force to prevent the reagent strip from being displaced when the sample needle punctures and extracts liquid.

6. The device according to claim 1, characterized in that The reagent strip motion assembly (300) includes a synchronous belt (308), a synchronous belt fixing block (309), a driving wheel (310), a stepping motor (311), a zero position sensor (315) and a zero position plate (316), wherein: The synchronous belt (308) is fixedly connected to the drag block (314) via the synchronous belt fixing block (309); The stepping motor (311) drives the driving wheel (310) to drive the synchronous belt (308), so that the reagent slide (303) moves along the linear guide rail (302); The zero position sensor (315) cooperates with the zero position piece (316) to calibrate the initial position of the reagent slide (303).

7. The device according to claim 6, characterized in that The reagent slide (303) is provided with a limit baffle (313) for limiting the motion range of the slide and cooperating with the zero position sensor (315) to ensure positioning accuracy.

8. The device according to claim 1, characterized in that The multi-wavelength light source assembly (100) further comprises a heat sink (104), which is in direct contact with the LED light source (101) and conducts heat away through a heat-conducting material to maintain a stable operating temperature of the light source.

9. The device according to claim 1, characterized in that The device supports the simultaneous detection of prothrombin time (PT), activated partial thromboplastin time (APTT), and fibrinogen (FIB), and each detection channel operates independently without interfering with each other.

10. The device according to claim 1, characterized in that The dichroic mirror (105) in the multi-wavelength light source assembly (100) selectively reflects or transmits light according to wavelength, specifically: The 340 nm wavelength light is reflected by the first dichroic mirror to the fiber combiner (106); The 405 nm wavelength light is reflected by the second dichroic mirror and then passes through the first dichroic mirror to the optical fiber combiner (106); The remaining wavelengths of light are separated and synthesized in turn through subsequent dichroic mirrors.

11. The device according to claim 6, characterized in that The zero position sensor (315) of the reagent strip motion component (300) interacts with the zero position piece to realize mechanical reset positioning, and the limit baffle (313) provided at the same time is used for physical calibration of the detection position of the reagent slide (303); the photoelectric detection circuit (207) of the multi-channel detection component (200) automatically starts light intensity signal acquisition in a predetermined detection time window based on the experimental process time program control, and forms an asynchronous control relationship with the displacement movement of the reagent slide (303), wherein: The zero position sensor (315) cooperates with the zero position piece to determine the initial coordinate origin; The light intensity signal acquisition cycle is independently controlled by the preset reaction time parameters of the coagulation test item. When the reagent slide (303) moves to the detection area, the photoelectric detection circuit (207) automatically performs transmission light intensity data collection and transmission according to the time trigger mechanism.

12. The device according to claim 1, characterized in that The output end of the optical fiber beam splitter (107) and the optical input end of the multi-channel detection component (200) are connected via an adjustable optical fiber connector.

13. The device according to claim 1, characterized in that The stepping motor (311) of the reagent strip motion assembly (300) drives the reagent slide (303) to move along the linear guide rail (302) via the synchronous belt (308). A driving wheel is installed at the shaft end of the stepper motor (311) of the reagent strip motion assembly (300), and a transmission pair is formed with a follower wheel installed on the rear side of the right side plate of the motion through a synchronous belt (308). The synchronous belt (308) is rigidly connected to the drag block through a synchronous belt pressure block. When the stepper motor (311) rotates, it is converted into linear motion through the driving wheel-synchronous belt transmission pair, driving the reagent slide (303) to make precise displacement along the linear guide rail.

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