Photoelectric wound repair hydrogel dressing

By utilizing the photoelectric and piezoelectric conversion of flexible materials, the problems of existing phototherapy requiring external power sources and poor biocompatibility have been solved, enabling self-powered wound healing, promoting tissue repair, and improving healing efficiency and quality.

CN121287980AActive Publication Date: 2026-01-09UNIV OF SCI & TECH BEIJING +1
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Patent Information

Application Number
CN202511669619.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-11-14
Publication Date
2026-01-09
Estimated Expiration
2045-11-14

AI Technical Summary

Technical Problem

Existing phototherapy methods mostly rely on single photothermal and photochemical effects to promote tissue healing, which have problems such as the need for an external power source and poor biocompatibility. They are also difficult to integrate photoelectric self-powered-biomechanical energy conversion micro-electric stimulation functions, resulting in low treatment efficiency for refractory wounds.

Method used

Using flexible materials, including a gel layer and an energy conversion layer, the gel layer contains healing-promoting active substances and conductive functional substances, and the energy conversion layer contains piezoelectric materials. It is prepared by electrospinning technology to achieve photoelectric conversion and piezoelectric conversion, and autonomously provide energy support for the wound.

Benefits of technology

Without relying on an external power source, it provides continuous electrical stimulation through photoelectric and piezoelectric conversion, promoting tissue repair, improving healing efficiency and quality, and possessing antioxidant, antibacterial and anti-inflammatory properties, providing a painless and non-invasive intelligent repair method.

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Abstract

The invention relates to the technical field of medical instruments, in particular to a photo-piezoelectric hydrogel dressing for wound repair. The hydrogel dressing realizes self-energized micro-electrical stimulation and anti-oxidation-antibacterial-anti-inflammatory integrated treatment through'energy-drug 'double closed-loop synergy: the PVDF / ZnO nanofiber on the upper layer can convert human body micro-motion and external light into micro-electrical stimulation to promote cell migration, proliferation and angiogenesis; the curcumin at the lower layer cooperates with the nano-silver to block the'oxidative stress-inflammation-infection 'vicious circle of chronic wounds. The dressing is soft and fit, does not need an external power supply, is excellent in biocompatibility, provides a self-driven multifunctional nursing scheme for refractory wounds, and has wide clinical popularization and market application prospects.
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