A quantitative injection device for radiopharmaceuticals in nuclear medicine

Abstract

This invention relates to the field of radiodiagnostic technology, specifically to a quantitative injection device for radiopharmaceuticals in nuclear medicine. The device includes an injection system, a waste liquid chamber at the bottom of the system, a waste liquid box within the waste liquid chamber, and a partition within the waste liquid box dividing the interior of the waste liquid box into several waste liquid tanks. Each waste liquid tank has a drive chamber and a recovery chamber arranged from top to bottom. Each recovery chamber contains a recovery component for collecting waste liquid generated during injection. Each drive chamber contains a drive component, which is used to seal and collect the waste liquid in one set of recovery components when the collection reaches its upper limit, and then switch to another set of recovery components to continue collecting waste liquid. A valve assembly is located on the top wall of the waste liquid chamber. This invention enables automatic switching and collection of waste liquid and simultaneous recovery of contaminated tubing, and achieves zero-contact replacement using a detachable waste liquid box, thereby completely avoiding direct contact between medical personnel and radioactive waste liquid and tubing during continuous injection.

Description

Technical Field

[0001] This invention relates to the field of radiodiagnostic technology, and more specifically to a quantitative injection device for radiopharmaceuticals in nuclear medicine. Background Technology

[0002] Nuclear medicine is an important branch of modern medicine that utilizes radiopharmaceuticals—labeled compounds containing radioactive nuclides—for the diagnosis and treatment of diseases. Taking positron emission tomography (PET) as an example, commonly used imaging agents include fluorine-18-labeled fluorodeoxyglucose (¹). 8 After being injected into the human body, radioactive fluorocarbons (RF-FDGs) reflect the metabolic activity of the organism by detecting the gamma rays released during their decay. However, while these radiopharmaceuticals bring value to precision medicine, their inherent ionizing radiation characteristics also pose a clear occupational exposure risk to medical personnel. Throughout the drug administration process, in addition to the drug primarily injected into the patient, a certain amount of radioactive waste is generated from residual tubing in the injection system, pre-filling, and flushing after failed injections. How to safely and efficiently collect and manage this waste, minimizing operator exposure, is one of the core challenges in radiation protection and workflow optimization in nuclear medicine.

[0003] To reduce radiation dose to personnel and improve drug delivery accuracy, automated injection systems, such as the Bayer PET automated drug delivery system and automated radiopharmaceutical dispensing and injection system, have been gradually applied in clinical practice. However, these devices still have significant limitations in waste management. A study conducted at Peking Union Medical College Hospital, comparing clinical injection with traditional injection methods using the Bayer PET automated drug delivery system, pointed out that, taking typical Intego equipment parameters as an example, the maximum capacity of its waste cartridge is usually 375ml. Considering that the pre-filling process consumes approximately 100ml of space, and that each patient receives 8-10ml of waste fluid during normal injection, plus an additional 35ml of flushing waste fluid in case of injection failure, a single bag can only support approximately 28-30 patients for continuous injection. While this capacity can meet the average daily workload, for large medical centers with high patient volumes, it is necessary to stop the machine mid-day and manually replace the full waste cartridge and connected contaminated tubing. This replacement procedure forces medical staff to come into close contact with waste containers and pipelines containing residual highly active radiopharmaceuticals, creating a new, avoidable radiation exposure risk. Furthermore, the manual disassembly process poses risks of leakage and contamination. Therefore, the current technology lacks a solution capable of handling large workloads, enabling automated waste collection and "zero-contact" replacement, which has become a key bottleneck restricting further improvements in clinical work efficiency and safety. Summary of the Invention

[0004] To address the aforementioned problems, this invention provides a quantitative injection device for radiopharmaceuticals in nuclear medicine, which enables automatic switching and collection of waste liquid and simultaneous recovery of contaminated pipelines. Furthermore, it utilizes a fully detachable waste liquid container to achieve zero-contact replacement, thereby completely preventing medical personnel from directly contacting radioactive waste liquid and pipelines during continuous injection.

[0005] To achieve the above objectives, the technical solution of the present invention is as follows: A quantitative injection device for radiopharmaceuticals in nuclear medicine includes an injection system. The lower part of the injection system is provided with a waste liquid chamber, and a waste liquid box is provided inside the waste liquid chamber. The waste liquid box is provided with a partition, which divides the interior of the waste liquid box into several waste liquid tanks. Each waste liquid tank is provided with a driving chamber and a recovery chamber from top to bottom. Each recovery chamber is provided with a recovery component for collecting waste liquid generated during the injection process. Each driving chamber is provided with a driving component. The driving component is used to close and collect the waste liquid in a certain group of recovery components when the waste liquid collected in a certain group of recovery components reaches the upper limit, and switch to another group of recovery components to continue collecting waste liquid. The top wall of the waste liquid chamber is provided with a valve component, which is used to switch the channel for waste liquid to enter any group of recovery components. Each drive assembly includes a drive box fixedly connected to the bottom wall of the drive cavity. A sliding groove is formed on the inner wall of the drive box, and a slider slides within the groove. A rack is fixedly connected to the side of the slider away from the groove. A first transmission rod is detachably connected to the bottom end of the rack. The bottom end of the first transmission rod extends into the recycling assembly and is fixedly connected to a piston plate, which senses the waste liquid level within the recycling assembly. A sensing component for transmitting the waste liquid level is provided on the rack, and the sensing component is electrically connected to a controller. A second transmission rod is rotatably connected to the inner wall of the drive box. A gear is coaxially fixedly connected to each second transmission rod. A take-up drum is detachably connected to the end of the second transmission rod away from the inner wall of the drive box. The gear meshes with the rack, and a waste liquid pipe is wound around the take-up drum. The inlet end of the waste liquid pipe communicates with a valve assembly, and a switch assembly for obtaining the waste liquid level and disconnecting the communication is provided at the connection point between the inlet end of the waste liquid pipe and the valve assembly. The outlet end of the waste liquid pipe passes through the drive box and communicates with the recycling assembly.

[0006] The technical principles of the above solution are as follows: During injection in the injection system, if waste liquid or water for injection is generated, the waste liquid flows into the main inlet of the valve assembly through the waste liquid discharge end of the injection system. The controller defaults to controlling the valve assembly to open the corresponding distribution port of one set of waste liquid tanks, allowing the waste liquid to flow into the waste liquid pipe of the corresponding drive assembly through the distribution port, and finally be injected into the recovery assembly from the outlet end of the waste liquid pipe. As the waste liquid accumulates in the recovery assembly, the liquid level gradually rises, and the piston plate slides upward synchronously. The piston plate pushes the rack along the groove on the inner side wall of the drive box through the first transmission rod. During the sliding process of the rack, on the one hand, it meshes with the gear to drive the second transmission rod and the coaxially fixed take-up drum to rotate synchronously. The take-up drum winds the waste liquid pipe in an orderly manner to prevent the waste liquid pipe from bending, tangling and jamming due to the rise in liquid level or the movement of the device. On the other hand, the sensing component on the rack detects the sliding displacement of the rack in real time, thereby indirectly obtaining the waste liquid level in the recovery assembly and continuously transmitting the liquid level signal to the controller. When the sensing component detects that the waste liquid level has reached the preset upper limit, the controller immediately controls the switching component to disconnect the current waste liquid pipe from the valve component's dispensing port to prevent waste liquid overflow. Simultaneously, the controller switches the valve component to the dispensing port corresponding to another incomplete recovery component, allowing subsequent waste liquid to flow into that recovery component through the new waste liquid pipe for continued collection. Furthermore, the controller can also control the electromagnetic cover on top of the currently full waste liquid tank to extend and close, achieving closed storage of the full recovery component. If there are multiple waste liquid tanks, the above switching process can be repeated until all recovery components are full of waste liquid. Then, the waste liquid box is removed entirely through its detachable structure for centralized processing of the full recovery components, without requiring disassembly of the core piping of the injection system.

[0007] The above approach has the following beneficial effects: 1. This solution uses a piston plate to directly sense the liquid level and a rack and pinion displacement triggering the control system. When a single waste liquid cylinder is nearly full, it automatically and quickly switches the flow of waste liquid to the next empty cylinder, ensuring continuous injection without manual intervention or downtime. Simultaneously, upon reaching full capacity, the system automatically disconnects the pipeline and closes the lid, keeping the waste liquid cylinder in a sealed environment within the shielded waste liquid tank. This significantly reduces the risk of operators coming into contact with radioactive waste liquid and suffering radiation exposure, improving the smoothness and safety of the workflow.

[0008] 2. In this solution, the lifting and lowering of the piston plate is converted into the rotation of the take-up drum via a rack and pinion mechanism, which can synchronously and automatically reel in the pipeline connected to the current waste liquid cylinder. This not only avoids the tangling, bending, or pulling of the hose due to changes in liquid level or equipment movement, ensuring smooth pipeline flow and reliable connection, but also utilizes a simple mechanical structure to achieve pipeline management linked to liquid level, improving the system's physical reliability, durability, and space utilization efficiency, and reducing failures caused by pipeline problems.

[0009] 3. In this solution, once all waste cartridges are used up, operators only need to remove the entire waste cartridge from the injection device, and it can be treated as a complete, internally sealed radioactive waste unit. This greatly simplifies the complexity and time required for waste replacement, avoids manual disassembly of individual waste cartridges or complex pipelines in a radioactive environment, reduces contact between medical personnel and nuclear materials, and facilitates centralized, shielded transport and disposal of waste, conforming to the practices of nuclear medicine waste management.

[0010] Furthermore, each recycling component includes a waste liquid cylinder, with the first transmission rod and piston plate located inside the waste liquid cylinder. The piston plate is slidably connected to the inner wall of the waste liquid cylinder, and the outlet end of the waste liquid pipe and the waste liquid cylinder are connected to the waste liquid cylinder.

[0011] Beneficial effects: The waste liquid cylinder provides a closed collection space for radioactive waste liquid, avoiding pollution caused by waste liquid leakage; the piston plate is directly immersed in the waste liquid in the waste liquid cylinder, which can intuitively and timely sense changes in liquid level; the first transmission rod can accurately transmit the displacement of the piston plate to the rack, providing a mechanical transmission basis for subsequent liquid level monitoring and automatic switching, ensuring the sealing of waste liquid collection and the accuracy of liquid level sensing.

[0012] Furthermore, each waste liquid cylinder has a fixed port at the top, which is fixedly connected to the bottom of the drive box. Each waste liquid cylinder has a fixed seat on the bottom wall of the recovery chamber, and the bottom of the waste liquid cylinder is snapped into the fixed seat.

[0013] Beneficial effects: The fixed fit between the top fixing port and the drive box, and the snap-fit ​​connection between the bottom and the fixing seat, achieve double fixation of the waste liquid cylinder in the recovery chamber, preventing the waste liquid cylinder from shaking or shifting when the waste liquid is injected or the device is moved, and ensuring the sealing of the connection between the waste liquid pipe and the waste liquid cylinder; the snap-fit ​​connection method facilitates the quick assembly and disassembly of the waste liquid cylinder, and there is no need to disassemble the complex structure when disposing of waste liquid in the future, thus improving the convenience of operation.

[0014] Furthermore, a flexible layer is provided around the inner sidewall of the recovery chamber.

[0015] Beneficial effects: The flexible layer can buffer the impact force on the waste liquid cylinder during waste liquid injection, reducing the risk of damage to the waste liquid cylinder caused by collision and friction; at the same time, it can fill the gap between the waste liquid cylinder and the inner wall of the recovery chamber, further restricting the displacement of the waste liquid cylinder, avoiding direct contact between the waste liquid cylinder and the rigid inner wall of the recovery chamber causing wear, extending the service stability of the waste liquid cylinder, and reducing the hidden danger of radioactive waste liquid leakage.

[0016] Furthermore, each switching assembly includes a magnetic block and an electromagnet. The magnetic blocks are all arranged in a ring around the inlet end of the waste liquid pipe, and the electromagnets are all located at the connection between the valve assembly and the inlet end of the waste liquid pipe. The electromagnets are all electrically connected to the controller.

[0017] Beneficial effects: By controlling the on and off of the electromagnet through the controller, the electromagnet can be attracted or separated from the magnetic block, thereby quickly controlling the opening and closing of the waste liquid inlet and the liquid distribution port of the valve assembly. The channel can be disconnected in time when the waste liquid reaches the upper limit of collection, effectively preventing the waste liquid from overflowing. Moreover, no manual operation is required, avoiding medical staff from coming into contact with radioactive pipelines and reducing the risk of radiation exposure.

[0018] Furthermore, several baffles are hinged to the inlet end of each waste liquid pipe.

[0019] Beneficial effects: The baffle plate, together with the magnetic block and electromagnet, forms a double sealing structure. When the electromagnet is de-energized and separates from the magnetic block, the baffle plate automatically closes under its own elasticity or the reverse action of the waste liquid pressure, sealing the inlet end of the waste liquid pipe and preventing the leakage of residual radioactive waste liquid or the diffusion of radioactive substances after the channel is disconnected. When the electromagnet is energized and attracts the magnetic block, the baffle plate is opened synchronously to ensure that the waste liquid channel is unobstructed and to improve the sealing and reliability of the channel opening and closing.

[0020] Furthermore, each sensing component includes an ultrasonic sensor installed on the top wall of the slide, and the ultrasonic sensors are all connected to the controller signal.

[0021] Beneficial effects: The ultrasonic sensor can detect the sliding displacement of the rack in real time, and indirectly calculate the liquid level in the waste liquid cylinder through the displacement. The ultrasonic sensor transmits the liquid level signal to the controller in real time, providing signal support for the controller to trigger the switching of the valve assembly and the on / off of the switch assembly, ensuring the stable operation of the automatic switching mechanism.

[0022] Furthermore, each waste liquid box has an opening on its top corresponding to the waste liquid tank, and each opening has a retractable electromagnetic cover on one side, which is connected to the controller signal.

[0023] Beneficial effects: When the waste liquid container is full of waste liquid, the controller can control the electromagnetic box cover to automatically extend and close, sealing the opening of the corresponding waste liquid tank, isolating the full waste liquid container from the external environment, blocking the spread of residual radioactive materials in the waste liquid container, and further reducing the radiation exposure risk of medical staff before disposal.

[0024] Furthermore, the valve assembly includes a solenoid directional valve electrically connected to the controller. The solenoid directional valve is provided with a main inlet and several branch inlets. The main inlet is connected to the injection system, and the branch inlets correspond one-to-one with the inlet end of the corresponding waste liquid pipe.

[0025] Beneficial effects: The electromagnetic reversing valve enables rapid switching of the liquid distribution port through the controller, and can accurately connect to the waste liquid pipes of different waste liquid tanks, ensuring seamless connection of waste liquid collection between multiple sets of waste liquid cylinders, and avoiding the disruption of the workflow due to interruption of waste liquid collection during continuous diagnosis and treatment.

[0026] Furthermore, the outer walls on both sides of the waste liquid box are provided with elastic buckles, and the inner wall of the waste liquid chamber is provided with buckle grooves corresponding to the elastic buckles.

[0027] Beneficial effects: The combination of the elastic buckle and the buckle groove enables a quick and detachable connection between the waste liquid box and the waste liquid chamber. Medical staff can install and remove the waste liquid box without the need for tools, making the operation convenient and efficient. During installation, the elastic buckle and the buckle groove precisely engage, ensuring that the waste liquid box is stable and does not shift during operation, and guaranteeing the reliability of the connection between the waste liquid tube and the valve assembly. The method of removing the waste liquid box as a whole avoids medical staff directly contacting the internal waste liquid cylinder and radioactive tubing, minimizing the risk of radiation exposure. Attached Figure Description

[0028] Figure 1 This is an isometric schematic diagram of an embodiment of the quantitative injection device for radiopharmaceuticals in nuclear medicine of the present invention; Figure 2 This is a front cross-sectional schematic diagram of the waste liquid chamber of an embodiment of the quantitative injection device for radiopharmaceuticals in nuclear medicine of the present invention; Figure 3 for Figure 2 Enlarged diagram of part A in the diagram; Figure 4 This is an isometric sectional view of the drive box of an embodiment of the quantitative injection device for radiopharmaceuticals in nuclear medicine of the present invention. Figure 5 This is an isometric view of the switching assembly of an embodiment of the quantitative injection device for radiopharmaceuticals in nuclear medicine of the present invention.

[0029] The reference numerals in the accompanying drawings include: 1. Injection system; 2. Waste liquid chamber; 3. Electromagnetic reversing valve; 4. Electromagnetic box cover; 5. Opening; 6. Drive chamber; 7. Flexible layer; 8. First transmission rod; 9. Waste liquid cylinder; 10. Fixing base; 11. Partition plate; 12. Waste liquid tank; 13. Piston plate; 14. Recovery chamber; 15. Fixing port; 16. Waste liquid pipe; 17. Drive box; 18. Gear; 19. Take-up drum; 20. Slider; 21. Rack; 22. Slide groove; 23. Second transmission rod; 24. Snap-in groove; 25. Elastic snap-in; 26. Baffle; 27. Magnetic block. Detailed Implementation

[0030] The technical solution of the present invention will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0031] In the description of this invention, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing the invention and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0032] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0033] The following detailed description illustrates the specific implementation method: Example:

[0034] During positron emission tomography (PET) drug injection in nuclear medicine, such as¹ 8 For F-FDG, traditional injection methods and existing partially automated equipment have limitations in radioactive waste management due to the limited capacity of a single waste cartridge. Even with complex scenarios including pre-filled waste, waste from normal patient injections, and additional flushing waste in case of injection failure, they can only support continuous injections for approximately 28-30 patients. For busy PET centers with more than 50 patients per day, medical staff must stop the machine mid-day to manually replace the full waste cartridge and its associated contaminated tubing. This replacement process poses two major risks: first, operators must be in close contact with waste cartridges and tubing containing residual highly active radiopharmaceuticals, facing unnecessary radiation exposure; second, the manual disassembly and reassembly process may cause waste spillage or aerosol diffusion, increasing the risk of environmental pollution and cross-contamination.

[0035] Therefore, the inventor creatively proposed the following: Figure 1 The device shown is a quantitative injection device for radiopharmaceuticals in the nuclear medicine department of a hospital. It was used to administer injections to 40 patients consecutively on a certain morning in the nuclear medicine department of a hospital.¹ 8Taking F-FDG PET / CT examination as an example, the procedure involves injection using an injection system 1. The injection system 1 has a waste fluid chamber 2 at its lower part, containing a waste fluid container. Both outer walls of the waste fluid container are equipped with elastic clips 25, and the inner wall of the waste fluid chamber 2 has clip grooves 24 corresponding to the elastic clips 25. Before the procedure begins, medical personnel align the pre-filled waste fluid container with the clip grooves 24 on the inner wall of the waste fluid chamber 2 using the elastic clips 25 on both sides and push it in to lock it in place.

[0036] The waste liquid box is equipped with a partition 11, such as Figure 2 As shown, the partition 11 divides the interior of the waste liquid box into several waste liquid tanks 12. The top of each waste liquid box is provided with an opening 5 corresponding to the waste liquid tank 12, and a retractable electromagnetic box cover 4 is provided on one side of each opening 5.

[0037] Each waste liquid tank 12 is equipped with a drive chamber 6 and a recovery chamber 14, arranged from top to bottom. Each recovery chamber 14 contains a recovery component for collecting waste liquid generated during injection. Each drive chamber 6 contains a drive component, which is used to seal and collect the waste liquid when the collection limit in one set of recovery components is reached, and then switch to another set of recovery components to continue collecting waste liquid. The top wall of the waste liquid chamber 2 is equipped with a valve component, which is used to switch the channel for waste liquid to enter either set of recovery components. When the waste liquid box is placed in the waste liquid chamber 2, the electromagnetic box cover 4 is always open, allowing medical personnel to manually connect the valve component, drive component, and recovery component pathways.

[0038] Each drive assembly includes a drive box 17 fixedly connected to the bottom wall of the drive cavity 6, such as Figure 3 and Figure 4 As shown, a groove 22 is opened on the inner side wall of the drive box 17. A slider 20 is slidably fitted in the groove 22. A rack 21 is fixedly connected to the side of the slider 20 away from the groove 22. A first transmission rod 8 is detachably connected to the bottom end of the rack 21. The bottom end of the first transmission rod 8 extends into the recycling assembly and is fixedly connected to a piston plate 13. The piston plate 13 is used to sense the liquid level of the waste liquid in the recycling assembly. A sensing component is provided on the rack 21 to transmit the liquid level of the waste liquid. The sensing component is electrically connected to the controller. Each sensing component includes an ultrasonic sensor set on the top wall of the groove 22. The ultrasonic sensors are all signal connected to the controller.

[0039] A second transmission rod 23 is rotatably connected to the inner wall of the drive box 17. A gear 18 is coaxially fixedly connected to each of the second transmission rods 23. A take-up drum 19 is detachably connected to one end of the second transmission rod 23 away from the inner wall of the drive box 17. The gear 18 meshes with the rack 21. A waste liquid pipe 16 is wound on the take-up drum 19. The inlet end of the waste liquid pipe 16 is connected to the valve assembly. The valve assembly includes an electromagnetic reversing valve 3 electrically connected to the controller. The electromagnetic reversing valve 3 is provided with a main liquid inlet and several liquid distribution ports. The main liquid inlet is connected to the injection system 1. The liquid distribution ports correspond one-to-one with the inlet end of the corresponding waste liquid pipe 16.

[0040] Furthermore, each inlet end of the waste liquid pipe 16 and the connection point of the solenoid directional valve 3 is equipped with a switch assembly for obtaining the waste liquid level and disconnecting the connection. Each switch assembly includes a magnetic block 27 and an electromagnet. The magnetic block 27 is arranged in a ring around the inlet end of the waste liquid pipe 16, and the electromagnet is located at the connection point between the solenoid directional valve 3 and the inlet end of the waste liquid pipe 16. The electromagnet is electrically connected to the controller. Several baffles 26 are hinged to the inlet end of the waste liquid pipe 16.

[0041] The outlet end of the waste liquid pipe 16 passes through the drive box 17 and communicates with the recycling assembly. Each recycling assembly includes a waste liquid cylinder 9. The first transmission rod 8 and the piston plate 13 are both located inside the waste liquid cylinder 9. The piston plate 13 is slidably connected to the inner wall of the waste liquid cylinder 9, and the outlet end of the waste liquid pipe 16 is connected to the waste liquid cylinder 9. A fixing port 15 is fixedly connected to the top of each waste liquid cylinder 9, and the fixing port 15 is fixedly connected to the bottom of the drive box 17. A fixing seat 10 is fixedly connected to the bottom wall of each recycling chamber 14, and the bottom of each waste liquid cylinder 9 is snap-fitted to the fixing seat 10. A flexible layer 7 is circumferentially formed on the inner wall of each recycling chamber 14.

[0042] Specifically, the injection system 1 begins operation. Approximately 100 ml of radioactive waste liquid generated during the pre-filling process flows through the waste liquid outlet, the main inlet of the valve assembly, and the first distributor of the injection system 1 into the waste liquid pipe 16 of the first waste liquid tank 12, and finally into the first waste liquid cylinder 9. Subsequently, 8-10 ml of waste liquid will be generated after each patient injection, or in the event of an injection failure, the injection system 1 will automatically inject 35 ml of flushing water. Both the flushing water and the waste liquid continuously flow into the first waste liquid cylinder 9.

[0043] As waste liquid and flushing water are injected, the liquid level in the first waste liquid cylinder 9 rises, squeezing and pushing the piston plate 13 upward. The piston plate 13 is rigidly connected to the first transmission rod 8 and pushes the rack 21, causing the rack 21, carrying the slider 20, to slide smoothly upward along the slide groove 22 of the drive box 17. When the rack 21 moves upward, it meshes with the gear 18, driving the second transmission rod 23 and the take-up drum 19 to rotate synchronously, orderly winding the waste liquid pipe 16 to prevent the pipe from sagging or interfering when the liquid level changes. In addition, an ultrasonic sensor fixed to the top wall of the slide groove 22 continuously measures the distance from the top surface of the rack 21. The signal of the distance from the top surface of the rack 21 accurately corresponds to the liquid level height and is transmitted to the controller in real time.

[0044] When the cumulative injections reach approximately the 25th patient, assuming one injection failure, the waste liquid volume in the first waste liquid cylinder 9 approaches the preset upper limit, such as 350ml. At this point, the piston plate 13 drives the rack 21 to rise to the trigger position, and the ultrasonic sensor detects that the signal has reached the threshold. First, the electromagnet at the inlet of the first waste liquid tube 16 is de-energized, causing the inlet end of the waste liquid tube 16 to disconnect from the dispensing port of the electromagnetic reversing valve 3. The magnetic poles of the baffle 26 at the inlet end of the waste liquid tube 16 repel the magnetic poles of the electromagnet. During connection, the electromagnet attracts the magnetic block 27 at the inlet end of the waste liquid tube 16, which repels the magnetic force of the baffle 26, thus causing the baffle 26 to be pushed open by the magnetic force and close to the inner wall of the waste liquid tube 16. When the electromagnet is disconnected, the magnetic field disappears, and the baffle 26 quickly closes under the reset action of the hinged spring force, sealing the opening of the waste liquid tube 16 and preventing residual liquid leakage. Next, the controller sends a command to the solenoid directional valve 3, connecting its main inlet to the branch outlet of the second waste liquid tank 12. Finally, the controller extends the solenoid cover 4 of the first waste liquid tank 12, closing the top opening 5 of the waste liquid tank 12. The entire process requires no interruption during the injection process, and the subsequently generated waste liquid immediately begins to flow to the second waste liquid cylinder 9.

[0045] Once all waste fluid cartridges 9 have been used, the controller issues a replacement prompt. Medical personnel can remove the entire waste fluid container from the injection device simply by pressing the elastic latch 25 release mechanism without touching any internal tubing or waste fluid cartridges 9. At this point, all waste fluid cartridges 9 are sealed within their respective destination recovery chambers 14. The top of the waste fluid tank 12 is sealed with an electromagnetic cover 4, and the inlet of the waste fluid pipe 16 is blocked by a baffle 26 and located within the take-up reel 19. The flexible layer 7 on the inner wall of the recovery chamber 14 uses a lead-rubber lining, which not only provides radiation shielding but also provides flexible buffering during the expansion of the waste fluid during recovery, preventing the waste fluid cartridges 9 from rupturing and spilling. The removed waste liquid box, as a complete and shielded radioactive waste unit, can be directly transported to the waste storage room for further processing. The side wall of the waste liquid box has a disassembly port. At this time, it is only necessary to remove the waste liquid cylinder 9, the first transmission rod 8 and the take-up cylinder 19 with the waste liquid tube 16 wound around it through the disassembly port for recycling and reinstalling new replacement parts. While saving manufacturing costs, it allows medical staff to prepare and uniformly process the waste after each day's PET injection examination, saving patients' waiting time and equipment downtime losses.

[0046] Obviously, the above embodiments are merely illustrative examples for clear explanation and are not intended to limit the implementation. Those skilled in the art will recognize that other variations or modifications can be made based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations here. However, obvious variations or modifications derived therefrom are still within the scope of protection of this invention.

Claims

1. A quantitative injection device for radiopharmaceuticals in nuclear medicine, comprising an injection system (1), wherein a waste liquid chamber (2) is provided at the lower part of the injection system (1), characterized in that, Waste liquid chamber (2) is provided with waste liquid box, and waste liquid box is provided with partition (11). The partition (11) divides the interior of waste liquid box into several waste liquid tanks (12). Each waste liquid tank (12) is provided with a drive chamber (6) and a recovery chamber (14) from top to bottom. Each recovery chamber (14) is provided with a recovery component for collecting waste liquid generated during the injection process. Each drive chamber (6) is provided with a drive component. The drive component is used to close and collect the waste liquid collected in a certain group of recovery components when the upper limit is reached, and switch to another group of recovery components to continue collecting waste liquid. The top wall of waste liquid chamber (2) is provided with a valve component. The valve component is used to switch the channel for waste liquid to enter any group of recovery components. Each drive assembly includes a drive box (17) fixedly connected to the bottom wall of the drive cavity (6). A groove (22) is opened on the inner side wall of the drive box (17). A slider (20) is slidably fitted in the groove (22). A rack (21) is fixedly connected to the side of the slider (20) away from the groove (22). A first transmission rod (8) is detachably connected to the bottom end of the rack (21). The bottom end of the first transmission rod (8) extends into the recycling assembly and is fixedly connected to a piston plate (13). The piston plate (13) is used to sense the waste liquid level in the recycling assembly. A sensing component for transmitting the waste liquid level is provided on the rack (21). The sensing component is electrically connected to a controller. The inner wall of the drive box (17) is rotatably connected to a second transmission rod (23), and a gear (18) is coaxially fixedly connected to the second transmission rod (23). The end of the second transmission rod (23) away from the inner wall of the drive box (17) is detachably connected to a take-up drum (19). The gear (18) meshes with the rack (21). A waste liquid pipe (16) is wound on the take-up drum (19). The inlet end of the waste liquid pipe (16) is connected to the valve assembly. A switch assembly for obtaining the waste liquid level and disconnecting the connection is provided at the connection between the inlet end of the waste liquid pipe (16) and the valve assembly. The outlet end of the waste liquid pipe (16) passes through the drive box (17) and is connected to the recycling assembly.

2. The quantitative injection device for radiopharmaceuticals in nuclear medicine according to claim 1, characterized in that, The recycling components all include a waste liquid cylinder (9), a first transmission rod (8) and a piston plate (13) located inside the waste liquid cylinder (9), the piston plate (13) is slidably connected to the inner wall of the waste liquid cylinder (9), and the outlet end of the waste liquid pipe (16) is connected to the waste liquid cylinder (9).

3. The quantitative injection device for radiopharmaceuticals in nuclear medicine according to claim 2, characterized in that, The top of the waste liquid cylinder (9) is fixedly connected to a fixing port (15), and the fixing port (15) is fixedly connected to the bottom of the drive box (17). The bottom wall of the recovery chamber (14) is fixedly connected to a fixing seat (10), and the bottom of the waste liquid cylinder (9) is snapped to the fixing seat (10).

4. The quantitative injection device for radiopharmaceuticals in nuclear medicine according to claim 3, characterized in that, A flexible layer (7) is provided on the inner wall of the recovery chamber (14).

5. The quantitative injection device for radiopharmaceuticals in nuclear medicine according to claim 4, characterized in that, Each switch assembly includes a magnetic block (27) and an electromagnet. The magnetic blocks (27) are all arranged around the inlet end of the waste liquid pipe (16), and the electromagnets are all located at the connection between the valve assembly and the inlet end of the waste liquid pipe (16). The electromagnets are all electrically connected to the controller.

6. The quantitative injection device for radiopharmaceuticals in nuclear medicine according to claim 5, characterized in that, Several baffles (26) are hinged to the inlet end of the waste liquid pipe (16).

7. The quantitative injection device for radiopharmaceuticals in nuclear medicine according to claim 6, characterized in that, All sensing components include ultrasonic sensors installed on the top wall of the slide (22), and the ultrasonic sensors are all connected to the controller signal.

8. The quantitative injection device for radiopharmaceuticals in nuclear medicine according to claim 7, characterized in that, Each waste liquid box has an opening (5) on the top corresponding to the waste liquid tank (12), and each opening (5) has a retractable electromagnetic cover (4) on one side. The electromagnetic cover (4) is connected to the controller signal.

9. The quantitative injection device for radiopharmaceuticals in nuclear medicine according to claim 8, characterized in that, The valve assembly includes a solenoid directional valve (3) electrically connected to the controller. The solenoid directional valve (3) is provided with a main inlet and several branch inlets. The main inlet is connected to the injection system (1), and the branch inlets correspond one-to-one with the inlet end of the corresponding waste pipe (16).

10. The quantitative injection device for radiopharmaceuticals in nuclear medicine according to claim 9, characterized in that, Both sides of the waste liquid box are provided with elastic buckles (25), and the inner side wall of the waste liquid chamber (2) is provided with buckle grooves (24) corresponding to the elastic buckles (25).

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