Magnetic bead sorting mechanism for blood coagulation test cup

Abstract

The utility model relates to a blood coagulation test cup magnetic bead sorting mechanism, and belongs to the field of blood coagulation test.The blood coagulation test cup magnetic bead sorting mechanism comprises a storage mechanism, a conveying mechanism and a sorting mechanism, the storage mechanism is used for storing magnetic beads, the conveying mechanism is used for conveying the magnetic beads to the sorting mechanism, and the sorting mechanism is used for adding the beads into a test cup at intervals. Under the combined action of the material storage mechanism, the material conveying mechanism and the sorting mechanism, automatic interval bead adding is achieved, and the testing efficiency and the testing precision are improved.

Description

Technical Field

[0001] The present application relates to the field of coagulation testing, and in particular to a magnetic bead sorting mechanism for a coagulation testing cup. Background Art

[0002] In recent years, with the continuous improvement of living standards, the incidence of hypertension, hyperglycemia and hyperlipidemia has increased significantly. Therefore, great progress has been made in the exploration of coagulation formation mechanisms and detection methods. The diagnosis and treatment of coagulation diseases and the resistance testing of anti-thrombotic drugs have achieved great results, bringing medical technology into a new stage.

[0003] Coagulation factors are activated in a certain order during the coagulation process. The complex catalytic effects between coagulation factors will cause some complex changes in the coagulation process. According to these biological or physical changes, the coagulation detection methods can be divided into immunological method, substrate colorimetric method and coagulation method. Among them, the coagulation method is further divided into current method, optical method and magnetic bead method.

[0004] The detection part of the magnetic bead coagulation function detector has an independent coil to generate a corresponding magnetic field. During the test, small magnetic beads are added to the test cup containing the sample to be tested, and the changing magnetic field is used to make the small magnetic beads move. As the plasma coagulates, the viscosity of the plasma gradually increases, and the swing amplitude of the small magnetic beads gradually decreases. The electromagnetic sensor in the instrument measures the swing amplitude of the magnetic beads and calculates the coagulation time.

[0005] When adding magnetic beads to the test cup, it is necessary to manually add the beads multiple times at intervals. The magnetic beads are not only easily contaminated, but it is also difficult to manually control the interval time of adding the beads, which affects the test accuracy and efficiency. Utility Model Content

[0006] In order to improve the problems of low efficiency of manual bead adding and difficulty in time control, the present application provides a magnetic bead sorting mechanism for a coagulation test cup.

[0007] The present application provides a coagulation test cup magnetic bead sorting mechanism that adopts the following technical solution:

[0008] A magnetic bead sorting mechanism for a coagulation test cup comprises: a storage mechanism, a feeding mechanism and a sorting mechanism, wherein the storage mechanism is used to store magnetic beads, the feeding mechanism is used to transport the magnetic beads to the sorting mechanism, and the sorting mechanism is used to add beads into the test cup at intervals.

[0009] By adopting the above technical solution, the storage mechanism temporarily stores the magnetic beads. When beads need to be added, the feeding mechanism transports the magnetic beads in the storage mechanism to the sorting mechanism, and the sorting mechanism adds the magnetic beads to the test cup at intervals. Under the joint action of the storage mechanism, the feeding mechanism and the sorting mechanism, automatic interval bead addition is realized, thereby improving the test efficiency and test accuracy.

[0010] Optionally: the material storage mechanism includes a frame and a material storage hopper arranged on the frame, a material feeding port is provided at the bottom of the material storage hopper, a lever is rotatably connected inside the material storage hopper, and a first driving component is provided on the frame for driving the lever to rotate so that the lever intermittently blocks the material feeding port.

[0011] By adopting the above technical solution, the magnetic beads are temporarily stored in the storage hopper, and the lever blocks the feed port. When beads need to be added, the first drive component drives the lever to rotate. When the lever is misaligned with the feed port, the magnetic beads pass through the feed port and enter the feed mechanism. In addition, during the bead adding process, the lever rotates continuously, thereby driving the magnetic beads to move, reducing the possibility of the magnetic beads getting stuck in the feed port.

[0012] Optionally: the first driving assembly includes a first motor arranged on a frame, and the shifting rod is arranged on a first output shaft of the first motor.

[0013] By adopting the above technical solution, the first motor is started, and the first motor drives the shifting rod to rotate, which has a simple structure and efficient transmission.

[0014] Optionally: a shift plate is provided on the end of the shift rod away from the first output shaft.

[0015] By adopting the above technical solution, the size of the shifting plate is larger than the shifting rod. On the one hand, the contact area between the shifting rod and the feeding port is increased, the blocking effect is improved, and the possibility of bead leakage is reduced; on the other hand, the contact area with the magnetic beads is increased, and the bead shifting effect is improved.

[0016] Optionally: the feeding mechanism includes a feeding pipe disposed on a frame and located below a storage hopper, the feeding pipe is connected to a feeding port, and a detection head for detecting the height of magnetic beads in the feeding pipe is provided on the frame, and the detection head is electrically connected to the first motor.

[0017] By adopting the above technical solution, the magnetic beads enter the feed pipe after passing through the feed port, and the magnetic beads are arranged in sequence in the feed pipe. When the detection head detects that the magnetic beads arranged in the feed pipe reach a predetermined height, the first motor stops, the paddle blocks the feed port, and the feeding stops; after the magnetic beads in the feed pipe enter the sorting mechanism, the height of the arranged magnetic beads in the feed pipe drops, the first motor starts, the paddle rotates, the feed port opens, and the feeding continues.

[0018] Optionally: the sorting mechanism includes a sorting bucket arranged on the frame and located below the conveying pipe, a sorting shaft is rotatably connected in the sorting bucket, a sorting slot is provided on the sorting shaft, a discharge pipe is provided on the sorting bucket below the sorting shaft, and a second driving component is provided on the frame for driving the sorting shaft to rotate so that the sorting slot is intermittently aligned with the conveying pipe and the discharge pipe.

[0019] By adopting the above technical solution, the second driving component drives the sorting shaft to rotate. When the sorting slot is aligned with the feed pipe, a magnetic bead in the feed pipe enters the sorting slot. The second driving component continues to drive the sorting shaft to rotate. When the sorting slot is aligned with the discharge pipe, the magnetic bead in the sorting slot passes through the discharge pipe and falls into the test cup.

[0020] Optionally: the second driving assembly includes a second motor arranged on the frame, and the sorting axis is arranged on a second output axis of the second motor.

[0021] By adopting the above technical solution, the second motor is started, and the second motor drives the sorting shaft to rotate, which has a simple structure and efficient transmission.

[0022] Optionally: a plurality of sorting slots are arranged on the sorting shaft.

[0023] By adopting the above technical solution, each sorting slot can transport magnetic beads, thereby improving the sorting efficiency. In addition, the rotation speed of the second motor is slowed down, which is energy-saving and environmentally friendly, and is consistent with the concept of sustainable development.

[0024] In summary, this application has the following beneficial effects:

[0025] With the joint action of the storage mechanism, the feeding mechanism and the sorting mechanism, automatic interval bead adding is realized, which improves the test efficiency and test accuracy. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 It is a schematic diagram of the overall structure of an embodiment of the present application;

[0027] Figure 2 It is a cross-sectional view of the overall structure of an embodiment of the present application.

[0028] Description of reference numerals:

[0029] 1. Material storage mechanism; 11. Frame; 12. Material storage hopper; 13. Material delivery port; 14. Push rod; 15. First drive assembly; 16. First motor; 18. Push plate; 2. Material delivery mechanism; 21. Material delivery pipe; 22. Detection head; 3. Sorting mechanism; 31. Sorting bucket; 32. Sorting shaft; 33. Sorting slot; 34. Discharge pipe; 35. Second drive assembly; 36. Second motor; 4. Test cup; 51. Bottom plate; 52. Vertical plate. DETAILED DESCRIPTION

[0030] The present application is further described in detail below in conjunction with the accompanying drawings.

[0031] This embodiment: a coagulation test cup magnetic bead sorting mechanism, refer to Figure 1 and Figure 2, including: a storage mechanism 1, a feeding mechanism 2 and a sorting mechanism 3 arranged from top to bottom, the storage mechanism 1 is used to store magnetic beads, the feeding mechanism 2 is used to transport the magnetic beads to the sorting mechanism 3, and the sorting mechanism 3 is used to add beads to the test cup 4 at intervals.

[0032] The storage mechanism 1 temporarily stores the magnetic beads. When beads need to be added, the feeding mechanism 2 conveys the magnetic beads in the storage mechanism 1 to the sorting mechanism 3. It should be noted that the feeding mechanism 2 is always full of beads, thereby improving the efficiency of bead delivery. Subsequently, the sorting mechanism 3 adds the magnetic beads to the test cup 4 at intervals. Automatic interval bead addition is achieved, which improves the test accuracy and test efficiency.

[0033] Among them, the storage mechanism 1 includes a frame 11 and a storage hopper 12 arranged on the frame 11, the frame 11 includes a bottom plate 51 and a vertical plate 52 fixedly connected to one side of the bottom plate 51, the storage hopper 12 is fixedly connected to the top of the vertical plate 52, the storage hopper 12 is funnel-shaped as a whole, the top of the storage hopper 12 is open, and a feeding port 13 is provided at the bottom of the storage hopper 12. A lever 14 is rotatably connected to the storage hopper 12, and a lever plate 18 is fixedly connected to the end of the lever 14, and the lever plate 18 is in contact with the inner wall of the storage hopper 12.

[0034] The frame 11 is provided with a first driving assembly 15 for driving the lever 14 to rotate so that the lever 14 intermittently blocks the feeding port 13. The first driving assembly 15 includes a first motor 16 mounted on the vertical plate 52 at a side away from the storage hopper 12, a first output shaft of the first motor 16 penetrates into the storage hopper 12, an end of the lever 14 away from the dial plate 18 is fixedly connected to the first output shaft of the first motor 16, and the lever 14 is perpendicular to the first output shaft.

[0035] When the feeding mechanism 2 is full of beads, the lever 14 is in a vertical downward position, the lever plate 18 blocks the feeding port 13, and the magnetic beads are located in the storage hopper 12. When the feeding mechanism 2 is not full of beads, the first motor 16 drives the lever 14 to rotate, and when the lever plate 18 is misaligned with the feeding port 13, the magnetic beads pass through the feeding port 13 and enter the feeding mechanism 2.

[0036] Among them, the feeding mechanism 2 includes a feeding pipe 21 fixedly connected to the vertical plate 52 and located below the storage hopper 12. The feeding pipe 21 is connected to the feeding port 13. The diameter of the feeding pipe 21 is adapted to the diameter of the magnetic beads. A detection head 22 for detecting the height of the magnetic beads in the feeding pipe 21 is also installed on the vertical plate 52. The detection head 22 is located on one side of the feeding pipe 21 near the top, and the detection head 22 is electrically connected to the first motor 16.

[0037] The magnetic beads passing through the feed port 13 fall into the feed pipe 21, and are arranged in sequence from bottom to top in the feed pipe 21. When the magnetic beads arranged in the feed pipe 21 reach a predetermined height, the detection head 22 transmits a signal to the first motor 16, the first motor 16 stops, the lever 14 points vertically downward, and the lever plate 18 blocks the feed port 13 to stop feeding.

[0038] When the magnetic beads in the conveying pipe 21 fall into the sorting mechanism 3, the height of the magnetic beads arranged in the conveying pipe 21 decreases, and the detection head 22 transmits a signal to the first motor 16. The first motor 16 drives the lever 14 to rotate, and the lever plate 18 is misaligned with the conveying port 13, and the magnetic beads in the storage hopper 12 continue to enter the conveying pipe 21.

[0039] Among them, the sorting mechanism 3 includes a sorting bucket 31 fixedly connected to the vertical plate 52 and located below the conveying pipe 21. The sorting bucket 31 is circular and hollow. A sorting shaft 32 is rotatably connected inside the sorting bucket 31. The outer wall of the sorting shaft 32 is in contact with the inner wall of the sorting bucket 31. Four sorting grooves 33 are arranged on the sorting shaft 32 along the axial direction of the sorting shaft 32. The sorting groove 33 can only accommodate one magnetic bead. A discharge pipe 34 is opened on the sorting bucket 31 directly below the sorting shaft 32.

[0040] The frame 11 is provided with a second driving assembly 35 for driving the sorting shaft 32 to rotate so that the sorting slot 33 is intermittently aligned with the conveying pipe 21 and the discharge pipe 34. The second driving assembly 35 includes a second motor 36 installed on the frame 11 away from the sorting bucket 31. The second output shaft of the second motor 36 penetrates into the sorting bucket 31, and the sorting shaft 32 is coaxially fixed to the second output shaft of the second motor 36.

[0041] When beads need to be added, the test cup 4 is placed under the discharge pipe 34, and the second motor 36 drives the sorting shaft 32 to rotate. When the sorting slot 33 is aligned with the delivery pipe 21, the magnetic beads in the delivery pipe 21 fall into the sorting slot 33, and the second motor 36 continues to drive the sorting shaft 32 to rotate. When the sorting slot 33 is aligned with the discharge pipe 34, the magnetic beads in the sorting slot 33 pass through the discharge pipe 34 and fall into the test cup 4.

[0042] The implementation principle of the magnetic bead sorting mechanism of the coagulation test cup of the present application embodiment is as follows: when the detection head 22 detects that the delivery tube 21 is full of beads, the lever 14 is downward, and the lever plate 18 blocks the delivery port 13. When the detection head 22 detects that the delivery tube 21 is not full of beads, the detection head 22 transmits a signal to the first motor 16, the first motor 16 is started, the first motor 16 drives the lever 14 to rotate, and the lever 14 drives the lever plate 18 to rotate. When the lever plate 18 is misaligned with the delivery port 13, the magnetic beads in the storage hopper 12 pass through the delivery port 13 and fall into the delivery tube 21 until the delivery tube 21 reaches the full state of beads.

[0043] When beads need to be added, the test cup 4 is placed under the discharge pipe 34, and the second motor 36 drives the sorting shaft 32 to rotate. When the sorting slot 33 is aligned with the feeding pipe 21, a magnetic bead falls into the sorting slot 33. The second motor 36 continues to drive the sorting shaft 32 to rotate. When the sorting slot 33 is aligned with the discharge pipe 34, the magnetic bead falls into the test cup 4, and this cycle is repeated until a predetermined number of magnetic beads are added to the test cup 4. Automatic interval bead addition is achieved, which improves the test accuracy and test efficiency.

[0044] The above are all preferred embodiments of the present application, and the protection scope of the present application is not limited thereto. Therefore, any equivalent changes made according to the structure, shape, and principle of the present application should be included in the protection scope of the present application.

Claims

1. A magnetic bead sorting mechanism for a coagulation test cup, characterized in that: include: A material storage mechanism (1), a material delivery mechanism (2) and a sorting mechanism (3), wherein the material storage mechanism (1) is used to store magnetic beads, the material delivery mechanism (2) is used to deliver the magnetic beads to the sorting mechanism (3), and the sorting mechanism (3) is used to add beads to the test cup (4) at intervals; The material storage mechanism (1) comprises a frame (11) and a material storage hopper (12) arranged on the frame (11); a material delivery port (13) is provided at the bottom of the material storage hopper (12); a lever (14) is rotatably connected inside the material storage hopper (12); and a first driving component (15) is provided on the frame (11) for driving the lever (14) to rotate so that the lever (14) intermittently blocks the material delivery port (13).

2. A magnetic bead sorting mechanism for a coagulation test cup according to claim 1, characterized in that: The first driving assembly (15) comprises a first motor (16) arranged on the frame (11), and the shifting rod (14) is arranged on a first output shaft of the first motor (16).

3. A magnetic bead sorting mechanism for a coagulation test cup according to claim 2, characterized in that: A shift plate (18) is provided on one end of the shift rod (14) away from the first output shaft.

4. The magnetic bead sorting mechanism for a coagulation test cup according to claim 1, characterized in that: The feeding mechanism (2) comprises a feeding pipe (21) disposed on a frame (11) and located below a storage hopper (12); the feeding pipe (21) is connected to a feeding port (13); a detection head (22) for detecting the height of magnetic beads in the feeding pipe (21) is disposed on the frame (11); the detection head (22) is electrically connected to a first motor (16).

5. A magnetic bead sorting mechanism for a coagulation test cup according to claim 4, characterized in that: The sorting mechanism (3) comprises a sorting bucket (31) arranged on a frame (11) and located below a conveying pipe (21); a sorting shaft (32) is rotatably connected in the sorting bucket (31); a sorting slot (33) is provided on the sorting shaft (32); a discharge pipe (34) is provided on the sorting bucket (31) and located below the sorting shaft (32); and a second driving component (35) is provided on the frame (11) for driving the sorting shaft (32) to rotate so that the sorting slot (33) is intermittently aligned with the conveying pipe (21) and the discharge pipe (34).

6. A magnetic bead sorting mechanism for a coagulation test cup according to claim 5, characterized in that: The second driving assembly (35) comprises a second motor (36) arranged on the frame (11), and the sorting shaft (32) is arranged on a second output shaft of the second motor (36).

7. The magnetic bead sorting mechanism for a coagulation test cup according to claim 5, characterized in that: The sorting shaft (32) is provided with a plurality of sorting slots (33) on its upper ring.

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