Solid-phase extraction device

Abstract

The utility model provides a solid-phase extraction device. The solid-phase extraction device comprises a base, a support frame, a liquid storage device and a liquid receiving assembly, the supporting frame is movably arranged on the base, the supporting frame is used for supporting the liquid storage device, a solid-phase extraction column is arranged in the liquid storage device, and the liquid storage device is used for storing liquid; the liquid receiving assembly comprises eggplant-shaped bottles, the base is provided with a plurality of mounting grooves, the mounting grooves are used for containing the eggplant-shaped bottles, the eggplant-shaped bottles are communicated with the liquid storage device, and the eggplant-shaped bottles are used for receiving liquid flowing out of the solid-phase extraction column. According to the rotary evaporation device, the problems that large-volume liquid passing through a solid-phase extraction column is received in an eggplant-shaped bottle and residual liquid after rotary evaporation needs to be transferred are solved, meanwhile, the problem that the liquid is prone to toppling over after a liquid storage device is installed is solved, and the working efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of detection and analysis, in particular to a solid phase extraction device. Background Art

[0002] Solid Phase Extraction (SPE) technology is a sample pretreatment method based on chromatographic separation. Solid phase extraction includes solid phase (solid adsorbent with certain functional groups) and liquid phase (sample and solvent). Liquid samples pass through a solid extraction device (solid phase extraction column, solid phase extraction membrane, solid phase extraction nozzle, solid phase extraction chip, etc.) equipped with solid adsorbent under the action of positive pressure, negative pressure or gravity.

[0003] Currently, solid phase extraction devices receive small volumes of liquid via graduated tubes.

[0004] However, the laboratory testing samples on the market can only receive small amounts of liquid after passing through the solid phase extraction column, and the calibrated tube has a small diameter, making it difficult to remove the remaining liquid. Utility Model Content

[0005] The main purpose of the utility model is to provide a solid phase extraction device, which solves the problem of receiving a large volume of liquid passing through a solid phase extraction column in an eggplant-shaped bottle and transferring the remaining liquid after rotary evaporation, and at the same time solves the problem of easy dumping after the liquid storage device is installed, thereby improving work efficiency.

[0006] To achieve the above-mentioned purpose, the utility model provides a solid phase extraction device, including a base, a support frame, a liquid reservoir and a liquid receiving assembly;

[0007] The support frame is movably arranged on the base, and is used to support the liquid reservoir, in which a solid phase extraction column is arranged, and the liquid reservoir is used to store liquid;

[0008] The liquid receiving assembly comprises an eggplant-shaped bottle, a base is provided with a plurality of mounting grooves, the mounting grooves are used to accommodate the eggplant-shaped bottle, the eggplant-shaped bottle is connected with the liquid storage device, and the eggplant-shaped bottle is used to receive the liquid flowing out through the solid phase extraction column.

[0009] The beneficial effects of the utility model are as follows: the stability of the eggplant-shaped bottle can be improved by setting the base; in addition, compared with the existing graduated tube that can only receive a small volume of liquid, when a large volume of liquid needs to be received, the volume of the graduated tube needs to be increased, and then the graduated tube after being increased is difficult to transfer the remaining liquid after rotary evaporation due to the small diameter of the graduated tube. Therefore, the present application can receive liquid through the eggplant-shaped bottle, which solves the problem of receiving a large volume of liquid that has passed through a solid phase extraction column in the eggplant-shaped bottle and needing to transfer the remaining liquid after rotary evaporation, and at the same time solves the problem of easy dumping after the installation of the liquid storage device, thereby improving work efficiency; and the liquid can be quickly and batch-transferred through the solid phase extraction column and the eggplant-shaped bottle, and the remaining liquid in the eggplant-shaped bottle can be conveniently transferred, the device has low cost, is easy to assemble, move and disassemble, and has strong scalability.

[0010] On the basis of the above technical solution, the present invention can also be improved as follows.

[0011] In some optional embodiments, a flexible gasket is disposed in the mounting groove, and the flexible gasket is attached to the groove wall of the mounting groove to wrap eggplant-shaped bottles of different volumes.

[0012] It should be noted that the design of the flexible gasket, due to its certain flexibility or elasticity, can, on the one hand, improve the installation stability of the eggplant-shaped bottle and further prevent the eggplant-shaped bottle from being bumped or damaged; on the other hand, it can be adapted to eggplant-shaped bottles of different volumes, that is, it can be adapted to eggplant-shaped bottles of different sizes, for example, three specifications of eggplant-shaped bottles: 50mL, 100mL, and 150mL.

[0013] In some optional embodiments, the base includes a plurality of partitions, and the plurality of partitions are staggered to form a plurality of mounting grooves.

[0014] It should be noted that the multiple partitions may include multiple longitudinal partitions and multiple transverse partitions, the multiple longitudinal partitions are arranged parallel to each other, the multiple transverse partitions are arranged parallel to each other, and the longitudinal partitions and the transverse partitions are arranged in an interlaced manner to form an installation groove.

[0015] In some optional embodiments, the liquid receiving assembly further includes a soft rubber part, and the soft rubber part is arranged at the bottle mouth of the eggplant-shaped bottle;

[0016] The soft rubber part has an opening, and the liquid outlet end of the liquid storage device passes through the opening and extends into the eggplant-shaped bottle.

[0017] It is understandable that the design of the soft rubber part ensures that the eggplant-shaped bottle is in a sealed state and improves the sealing performance.

[0018] In some optional embodiments, the liquid receiving assembly further includes a connecting tube, one end of which is inserted into the eggplant-shaped bottle, and the other end of which is connected to the atmosphere.

[0019] It is understandable that the design of the connecting tube allows the air pressure in the inner cavity of the eggplant-shaped bottle to be kept consistent with the external atmospheric pressure as much as possible, so that the liquid in the liquid reservoir can flow to the eggplant-shaped bottle through the liquid outlet of the liquid reservoir.

[0020] In some optional embodiments, the liquid receiving assembly further includes a control valve, which is disposed at the liquid outlet end of the liquid reservoir to control the flow rate of the liquid flowing into the eggplant-shaped bottle.

[0021] It can be understood that the design of the control valve can better control the flow rate of the liquid.

[0022] In some optional embodiments, a telescopic assembly is further included, the telescopic assembly includes a first telescopic rod and a second telescopic rod, the first telescopic rod is connected to the base, and the second telescopic rod is connected to the support frame;

[0023] One of the first telescopic rod and the second telescopic rod is provided with a limit block, and the other of the first telescopic rod and the second telescopic rod is provided with a plurality of limit holes, which are arranged along the length direction of the second telescopic rod, and the limit block and the plurality of limit holes match each other, and the limit block is inserted into the limit hole to fix the second telescopic rod.

[0024] It should be noted that the arrangement of the telescopic assembly allows the distance between the base and the support frame to be adjusted, and the height can be adjusted according to the eggplant-shaped bottle and liquid reservoir used, making the entire device more adaptable.

[0025] In some optional embodiments, the liquid reservoir includes a first syringe and a second syringe that are interconnected, and the first syringe is located above the second syringe;

[0026] The aperture of the second syringe is smaller than that of the first syringe, and the solid phase extraction column is located in the second syringe.

[0027] It should be noted that the liquids stored in the first syringe and the second syringe are consistent. The setting of the first syringe with a large aperture allows the experimenter to transfer the liquid in one go, thus solving the problem of the experimenter having to add liquid repeatedly.

[0028] In some optional embodiments, the liquid reservoir further comprises a connector, a liquid inlet end of the connector is connected to a liquid outlet end of the first syringe, and a liquid outlet end of the connector is connected to a liquid inlet end of the second syringe;

[0029] The radial dimension of the liquid inlet end of the connector is greater than the radial dimension of the liquid outlet end of the connector.

[0030] It should be noted that the provision of the connector facilitates the stability of the connection between the first syringe and the second syringe, and improves the sealing between the first syringe and the second syringe.

[0031] In some optional embodiments, the support frame is a mesh structure; and / or,

[0032] The supporting frame is made of elastic material.

[0033] It should be noted that such a configuration can better fix multiple liquid reservoirs, and has a simple structure and low cost. The support frame made of elastic material can fix liquid reservoirs of different sizes, and has higher adaptability.

[0034] The solid phase extraction device provided by the utility model comprises a base, a support frame, a liquid reservoir and a liquid receiving assembly; the support frame is movably arranged on the base, the support frame is used to support the liquid reservoir, a solid phase extraction column is arranged in the liquid reservoir, and the liquid reservoir is used to store liquid; the liquid receiving assembly comprises an eggplant-shaped bottle, the base is provided with a plurality of mounting grooves, the mounting grooves are used to accommodate the eggplant-shaped bottle, the eggplant-shaped bottle is connected with the liquid reservoir, and the eggplant-shaped bottle is used to receive the liquid flowing out through the solid phase extraction column.

[0035] The stability of the eggplant-shaped bottle can be improved by setting the base; in addition, compared with the existing graduated tube that can only receive a small volume of liquid, when a large liquid needs to be received, the volume of the graduated tube needs to be increased, and then the graduated tube after being increased is difficult to transfer the remaining liquid after rotary evaporation due to the small diameter of the graduated tube. Therefore, the present application can receive liquid through the eggplant-shaped bottle, which solves the problem of receiving a large volume of liquid that has passed through the solid phase extraction column in the eggplant-shaped bottle and the need to transfer the remaining liquid after rotary evaporation, and at the same time solves the problem of easy dumping after the installation of the liquid storage device, thereby improving work efficiency; and the liquid can be quickly and batch-transferred through the solid phase extraction column and the eggplant-shaped bottle, and the remaining liquid in the eggplant-shaped bottle can be easily transferred, the device has low cost, is easy to assemble, move and disassemble, and has strong scalability. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0037] Figure 1 A schematic diagram of the structure of a solid phase extraction device provided in an embodiment of the present application;

[0038] Figure 2 A schematic diagram of the structure of a base in a solid phase extraction device provided in an embodiment of the present application;

[0039] Figure 3 A schematic diagram of the structure of a liquid receiving component in a solid phase extraction device provided in an embodiment of the present application;

[0040] Figure 4 A schematic diagram of the structure of a telescopic component in a solid phase extraction device provided in an embodiment of the present application;

[0041] Figure 5 A schematic diagram of the structure of a support frame in a solid phase extraction device provided in an embodiment of the present application.

[0042] Description of reference numerals:

[0043] 100-solid phase extraction device;

[0044] 110- base;

[0045] 111-installation slot;

[0046] 112- flexible gasket;

[0047] 120-support frame;

[0048] 130 - fluid reservoir;

[0049] 131-first syringe;

[0050] 132-second syringe;

[0051] 133-connector;

[0052] 140-wetted component;

[0053] 141- Eggplant-shaped bottle;

[0054] 142-soft plastic parts;

[0055] 143-connecting pipe;

[0056] 144-control valve;

[0057] 150- telescopic component;

[0058] 151-first telescopic rod;

[0059] 1511-limiting hole;

[0060] 152- second telescopic rod;

[0061] 1521-limit block;

[0062] 160-Solid phase extraction column. DETAILED DESCRIPTION

[0063] In order to make the purpose, technical solution and advantages of the embodiment of the utility model clearer, the technical solution in the embodiment of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiment of the utility model. Obviously, the described embodiment is a part of the embodiment of the utility model, not all of the embodiments. Based on the embodiment of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model. All other embodiments obtained are within the scope of protection of the utility model. In the absence of conflict, the following embodiments and features in the embodiments can be combined with each other.

[0064] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0065] In the present utility model, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0066] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.

[0067] At present, solid phase extraction devices receive small volumes of liquid through graduated tubes. However, the devices available in the market can only receive small volumes of liquid after the samples have passed through the solid phase extraction column, and the graduated tubes have small diameters, making it difficult to remove the remaining liquid.

[0068] In order to overcome the defects in the prior art, the solid phase extraction device provided by the utility model can improve the stability of the eggplant-shaped bottle by setting the base; in addition, compared with the existing graduated tube that can only receive a small volume of liquid, when it is necessary to receive a large liquid, the volume of the graduated tube needs to be increased, and then the graduated tube after being increased is difficult to transfer the remaining liquid after rotary evaporation due to the small diameter of the graduated tube. Therefore, the present application can receive liquid through the eggplant-shaped bottle, which solves the problem of receiving a large volume of liquid that has passed through the solid phase extraction column in the eggplant-shaped bottle and the need to transfer the remaining liquid after rotary evaporation. At the same time, it solves the problem of easy dumping after the liquid storage device is installed, thereby improving work efficiency; and it can quickly pass the liquid through the solid phase extraction column and the eggplant-shaped bottle in batches, and it is convenient to transfer the remaining liquid in the eggplant-shaped bottle. The device has low cost, is easy to assemble, move and disassemble, and has strong scalability.

[0069] The content of the utility model will be described in detail below with reference to the accompanying drawings so that those skilled in the art can understand the content of the utility model more clearly and in detail.

[0070] Figure 1 This is a schematic diagram of the structure of the solid phase extraction device provided in the embodiment of the present application. Figure 2 This is a schematic diagram of the structure of the base in the solid phase extraction device provided in an embodiment of the present application.

[0071] like Figure 1 and Figure 2 As shown, the embodiment of the present application provides a solid phase extraction device 100, including a base 110, a support frame 120, a liquid reservoir 130 and a liquid receiving assembly 140;

[0072] In some embodiments, the base 110 may be a metal piece, and its material may include one or more of copper, iron, aluminum, tin, and lead. The material of the casting mold may be one of sand, metal, or ceramic.

[0073] In other examples, the base 110 may also be made of plastic. During injection molding, molten plastic is injected into a plastic product mold under pressure, and cooled and molded to obtain the desired plastic part.

[0074] It should be noted that the base 110 may also be made of transparent polymer materials such as polycarbonate to facilitate observation of the internal conditions.

[0075] The support frame 120 is movably disposed on the base 110, and the support frame 120 is used to support the liquid reservoir 130. The liquid reservoir 130 is provided with a solid phase extraction column 160, and the liquid reservoir 130 is used to store liquid;

[0076] It should be noted that the support frame 120 is provided to improve the stability of the installation and movement of the liquid reservoir 130 .

[0077] In some embodiments, the support frame 120 and the base 110 may be installed in a detachable or fixed connection manner, such as a bolt or snap connection manner.

[0078] In some examples, the support frame 120 may be a metal member, and its material may include one or more of copper, iron, aluminum, tin, and lead.

[0079] In other embodiments, the support frame 120 may be a hard plastic piece.

[0080] Exemplarily, the support frame 120 may be a hard plastic part made of polyoxymethylene material.

[0081] In some examples, the support frame 120 and the base 110 may be connected by a detachable connection or a fixed connection, such as by bolts, buckles or hanging connections. Specifically, the embodiments of the present application are not too restrictive.

[0082] The liquid receiving assembly 140 includes an eggplant-shaped bottle 141 . The base 110 is provided with a plurality of mounting grooves 111 for accommodating the eggplant-shaped bottle 141 . The eggplant-shaped bottle 141 is connected to the liquid reservoir 130 and is used to receive liquid flowing out of the solid phase extraction column 160 .

[0083] It should be noted that there are multiple eggplant-shaped bottles 141 , and the mounting groove 111 is used to fix the eggplant-shaped bottle 141 so that the eggplant-shaped bottle 141 can be stably placed on the base 110 . Therefore, the shape of the mounting groove 111 matches the shape of the eggplant-shaped bottle 141 .

[0084] It should be noted that solid-phase extraction (SPE) is a sample pretreatment technology developed in recent years, which is developed by combining liquid-solid extraction columns and liquid chromatography technology. It is mainly used for sample separation, purification and concentration. Compared with traditional liquid-liquid extraction, it can improve the recovery rate of analytes, more effectively separate analytes from interfering components, reduce sample pretreatment processes, and is simple to operate, time-saving and labor-saving. It is widely used in the fields of medicine, food, environment, commodity inspection, chemical industry, etc.

[0085] In addition, it should be noted that the whole process is: first, a liquid containing a sample is stored in the liquid reservoir 130, wherein the liquid containing the sample contains other components besides the sample, the liquid containing the sample passes through the solid phase extraction column 160, and then the sample remains on the solid phase extraction column 160, and other components flow into the eggplant-shaped bottle 141 through the solid phase extraction column 160, and then the liquid in the eggplant-shaped bottle 141 is poured out; then, a solvent is poured into the liquid reservoir 130, and the purpose of the solvent is to wash away the sample remaining on the solid phase extraction column 160, and then the solvent washes the sample into the eggplant-shaped bottle 141, and at this time, the solvent and the sample are stored in the eggplant-shaped bottle 141; finally, the eggplant-shaped bottle 141 is subjected to rotary evaporation to finally retain the sample.

[0086] Through the above-mentioned arrangement, that is, through the arrangement of the base 110, the stability of the eggplant-shaped bottle 141 can be improved; in addition, compared with the existing graduated tube that can only receive a small volume of liquid, when a large liquid needs to be received, the volume of the graduated tube needs to be increased, and then the graduated tube after being increased is difficult to transfer the remaining liquid after rotary evaporation due to the small diameter of the graduated tube. Therefore, the present application can receive liquid through the eggplant-shaped bottle 141, which solves the problem of receiving a large volume of liquid that has passed through the solid phase extraction column 160 in the eggplant-shaped bottle 141 and the need to transfer the remaining liquid after rotary evaporation, and at the same time solves the problem of easy dumping after the installation of the liquid storage device 130, thereby improving work efficiency; and the liquid can be quickly and batch-transferred through the solid phase extraction column 160 and the eggplant-shaped bottle 141, and the remaining liquid in the eggplant-shaped bottle 141 can be conveniently transferred, the device has low cost, is easy to assemble, move and disassemble, and has strong scalability.

[0087] like Figure 1 and Figure 2 As shown, in some optional embodiments, a flexible gasket 112 is disposed in the mounting groove 111 , and the flexible gasket 112 is attached to the groove wall of the mounting groove 111 to wrap eggplant-shaped bottles 141 of different volumes.

[0088] It should be noted that the design of the flexible gasket 112, due to its certain flexibility or elasticity, can, on the one hand, improve the installation stability of the eggplant-shaped bottle 141 and further prevent the eggplant-shaped bottle 141 from being damaged; on the other hand, it can be adapted to eggplant-shaped bottles 141 of different volumes, that is, it can be adapted to eggplant-shaped bottles 141 of different sizes, for example, three specifications of eggplant-shaped bottles 141 of 50mL, 100mL, and 150mL.

[0089] In some embodiments, the flexible gasket 112 may be made of foam material, or may be a foam layer.

[0090] In some optional embodiments, the base 110 includes a plurality of partitions, and the plurality of partitions are staggered to form a plurality of mounting grooves 111 .

[0091] It should be noted that the multiple partitions may include multiple longitudinal partitions and multiple transverse partitions, the multiple longitudinal partitions are arranged parallel to each other, the multiple transverse partitions are arranged parallel to each other, and the longitudinal partitions and the transverse partitions are arranged in an interlaced manner to form the installation groove 111.

[0092] Figure 3 The schematic diagram of the structure of the liquid receiving component in the solid phase extraction device provided in the embodiment of the present application is as follows: Figures 1 to 3 As shown, in some optional embodiments, the liquid receiving assembly 140 further includes a soft plastic member 142, and the soft plastic member 142 is disposed at the bottle mouth of the eggplant-shaped bottle 141;

[0093] The soft plastic member 142 has an opening, and the liquid outlet end of the liquid storage container 130 passes through the opening and extends into the eggplant-shaped bottle 141 .

[0094] It is understandable that the design of the soft rubber part 142 ensures that the eggplant-shaped bottle 141 is in a sealed state, thereby improving the sealing performance.

[0095] In some examples, the material of the soft rubber part 142 may be nitrile rubber, acrylic rubber, etc., which is not specifically set in the embodiment of the present application.

[0096] Optionally, the soft plastic part 142 is rubber.

[0097] For example, the soft rubber part 142 may be vulcanized rubber. Vulcanized rubber refers to unvulcanized rubber formed by vulcanization. Unvulcanized rubber includes natural rubber, diene-based synthetic rubber, and the like.

[0098] The cold vulcanization method is to use a solution mixed with sulfur chloride, carbon disulfide, carbon tetrachloride and benzene, apply it to the surface of raw unvulcanized rubber or immerse the unvulcanized rubber in this solution. After several hours, the vulcanization process is completed.

[0099] Exemplarily, the soft rubber member 142 is made of vulcanized rubber, which can make the soft rubber member 142 less likely to break and have higher elasticity.

[0100] like Figures 1 to 3 As shown, in some optional embodiments, the liquid receiving assembly 140 further includes a connecting tube 143, one end of the connecting tube 143 is inserted into the eggplant-shaped bottle 141, and the other end of the connecting tube 143 is connected to the atmosphere.

[0101] It is understandable that the design of the connecting tube 143 makes the air pressure in the inner cavity of the eggplant-shaped bottle 141 as consistent as possible with the external atmospheric pressure, so that the liquid in the liquid reservoir 130 can flow to the eggplant-shaped bottle 141 through the liquid outlet of the liquid reservoir 130.

[0102] In some examples, the connecting tube 143 extends into the inner cavity of the eggplant-shaped bottle 141 and is located at the upper end of the eggplant-shaped bottle 141. Or it can be located at other positions as long as the purpose can be achieved, and the embodiments of the present application are not too limited here.

[0103] like Figures 1 to 3 As shown, in some optional embodiments, the liquid receiving assembly 140 further includes a control valve 144 , which is disposed at the liquid outlet end of the liquid reservoir 130 to control the flow rate of the liquid flowing into the eggplant-shaped bottle 141 .

[0104] It can be understood that the design of the control valve 144 can better control the flow rate of the liquid.

[0105] In some examples, the control valve 144 and the liquid outlet of the liquid reservoir 130 may be connected in a detachable connection or a fixed connection, such as by bolts, buckles or hanging connections. Specifically, the embodiments of the present application are not too restrictive here.

[0106] Figure 4 A schematic diagram of the structure of the telescopic component in the solid phase extraction device provided in the embodiment of the present application, such as Figures 1 to 4 As shown, in some optional embodiments, a telescopic assembly 150 is further included, and the telescopic assembly 150 includes a first telescopic rod 151 and a second telescopic rod 152, the first telescopic rod 151 is connected to the base 110, and the second telescopic rod 152 is connected to the support frame 120;

[0107] A limit block 1521 is provided on one of the first telescopic rod 151 and the second telescopic rod 152, and a plurality of limit holes 1511 are provided on the other of the first telescopic rod 151 and the second telescopic rod 152. The plurality of limit holes 1511 are arranged along the length direction of the second telescopic rod 152, and the limit block 1521 and the plurality of limit holes 1511 match each other, and the limit block 1521 is inserted into the limit hole 1511 to fix the second telescopic rod 152.

[0108] It should be noted that the arrangement of the telescopic assembly 150 allows the distance between the base 110 and the support frame 120 to be adjusted, and the height can be adjusted according to the eggplant-shaped bottle 141 and the liquid reservoir 130 used, making the entire device more adaptable.

[0109] In some embodiments, the first telescopic rod 151 and the base 110 may be installed in a detachable or fixed connection manner, for example, a bolt or a snap connection manner.

[0110] The second telescopic rod 152 and the support frame 120 may be installed in a detachable or fixed connection manner, for example, a bolt or a snap connection manner.

[0111] It should be noted that the length direction of the first telescopic rod 151 is consistent with the length direction of the second telescopic rod 152 , and the second telescopic rod 152 can move along the length direction of the first telescopic rod 151 to adjust the distance between the base 110 and the support frame 120 .

[0112] In some embodiments, the first telescopic rod 151 is provided with a limit block 1521 , and the second telescopic rod 152 is provided with a plurality of limit holes 1511 , or the second telescopic rod 152 is provided with a limit block 1521 , and the first telescopic rod 151 is provided with a plurality of limit holes 1511 .

[0113] In addition, the limiting block 1521 can be made of elastic material, so that it can be inserted into the limiting hole 1511 and can pop out from the limiting hole 1511 at the same time.

[0114] like Figures 1 to 4 As shown, in some optional embodiments, the liquid reservoir 130 includes a first syringe 131 and a second syringe 132 that are interconnected, and the first syringe 131 is located above the second syringe 132;

[0115] The aperture of the second syringe 132 is smaller than that of the first syringe 131 , and the solid phase extraction column 160 is located in the second syringe 132 .

[0116] It should be noted that the liquids stored in the first syringe 131 and the second syringe 132 are consistent. The setting of the first syringe 131 with a large aperture allows the experimenter to transfer the liquid at one time, thus solving the problem of the experimenter repeatedly adding liquid.

[0117] Specifically, a liquid containing a sample is first transferred into the second syringe 132, wherein the liquid containing the sample contains other components besides the sample, the liquid containing the sample passes through the solid phase extraction column 160, and then the sample remains on the solid phase extraction column 160, and other components flow into the eggplant-shaped bottle 141 through the solid phase extraction column 160, and then the liquid in the eggplant-shaped bottle 141 is poured out. Since the present application is to receive a large volume of liquid, the first syringe 131 is connected to the second syringe 132, so that the experimenter can transfer the liquid at one time to avoid repeated injections until all the liquid containing the sample passes through the solid phase extraction column 160; then a solvent is poured into the first syringe 131 and the second syringe 132, the purpose of the solvent is to wash away the sample remaining on the solid phase extraction column 160, and then the solvent washes the sample into the eggplant-shaped bottle 141, and at this time the eggplant-shaped bottle 141 stores the solvent and the sample; finally, the eggplant-shaped bottle 141 is subjected to rotary evaporation to finally retain the sample.

[0118] In some optional embodiments, the liquid reservoir 130 further includes a connector 133, the liquid inlet end of the connector 133 is connected to the liquid outlet end of the first syringe 131, and the liquid outlet end of the connector 133 is connected to the liquid inlet end of the second syringe 132;

[0119] The radial dimension of the liquid inlet end of the connector 133 is greater than the radial dimension of the liquid outlet end of the connector 133 .

[0120] It should be noted that the provision of the connector 133 facilitates the stability of the connection between the first syringe 131 and the second syringe 132 , and improves the sealing between the first syringe 131 and the second syringe 132 .

[0121] In some embodiments, the connector 133 may be a funnel.

[0122] In other embodiments, the connector 133 may be made of plastic material.

[0123] Figure 5 A schematic diagram of the structure of the support frame in the solid phase extraction device provided in the embodiment of the present application, such as Figure 5 As shown, in some optional embodiments, the support frame 120 is a mesh structure; and / or,

[0124] The support frame 120 is made of elastic material.

[0125] It should be noted that such a configuration can better fix multiple liquid reservoirs 130, and has a simple structure and low cost. The support frame 120 made of elastic material can fix liquid reservoirs 130 of different sizes, and has higher adaptability.

[0126] The solid phase extraction device provided in the embodiment of the present application includes a base, a support frame, a liquid reservoir and a liquid receiving assembly; the support frame is movably arranged on the base, the support frame is used to support the liquid reservoir, a solid phase extraction column is arranged in the liquid reservoir, and the liquid reservoir is used to store liquid; the liquid receiving assembly includes an eggplant-shaped bottle, the base is provided with a plurality of mounting grooves, the mounting grooves are used to accommodate the eggplant-shaped bottle, the eggplant-shaped bottle is connected to the liquid reservoir, and the eggplant-shaped bottle is used to receive liquid flowing out through the solid phase extraction column.

[0127] The stability of the eggplant-shaped bottle can be improved by setting the base; in addition, compared with the existing graduated tube that can only receive a small volume of liquid, when a large liquid needs to be received, the volume of the graduated tube needs to be increased, and then the graduated tube after being increased is difficult to transfer the remaining liquid after rotary evaporation due to the small diameter of the graduated tube. Therefore, the present application can receive liquid through the eggplant-shaped bottle, which solves the problem of receiving a large volume of liquid that has passed through the solid phase extraction column in the eggplant-shaped bottle and the need to transfer the remaining liquid after rotary evaporation, and at the same time solves the problem of easy dumping after the installation of the liquid storage device, thereby improving work efficiency; and the liquid can be quickly and batch-transferred through the solid phase extraction column and the eggplant-shaped bottle, and the remaining liquid in the eggplant-shaped bottle can be easily transferred, the device has low cost, is easy to assemble, move and disassemble, and has strong scalability.

[0128] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.

[0129] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present utility model, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0130] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, ordinary technicians in this field should understand that they can still modify the technical solutions recorded in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not make the essence of the corresponding technical solution deviate from the scope of the technical solution of the embodiments of the utility model.

Claims

1. A solid phase extraction device, characterized in that: It includes a base, a support frame, a liquid reservoir and a liquid connection component; The support frame is movably arranged on the base, and the support frame is used to support the liquid reservoir, a solid phase extraction column is arranged in the liquid reservoir, and the liquid reservoir is used to store liquid; The liquid reservoir comprises a first syringe and a second syringe that are interconnected, wherein the first syringe is located above the second syringe; The aperture of the second syringe is smaller than that of the first syringe, and the solid phase extraction column is located in the second syringe; The liquid receiving assembly includes an eggplant-shaped bottle, the base is provided with a plurality of mounting grooves, the mounting grooves are used to accommodate the eggplant-shaped bottle, the eggplant-shaped bottle is connected to the liquid reservoir, and the eggplant-shaped bottle is used to receive the liquid flowing out of the solid phase extraction column.

2. The solid phase extraction device according to claim 1, characterized in that: A flexible gasket is arranged in the installation groove, and the flexible gasket is attached to the groove wall of the installation groove to wrap the eggplant-shaped bottles of different volumes.

3. The solid phase extraction device according to claim 1, characterized in that: The base includes a plurality of partitions, and the plurality of partitions are staggered to form a plurality of mounting grooves.

4. The solid phase extraction device according to any one of claims 1 to 3, characterized in that: The liquid receiving assembly further comprises a soft rubber part, and the soft rubber part is arranged at the bottle mouth of the eggplant-shaped bottle; The soft plastic part has an opening, and the liquid outlet end of the liquid storage device passes through the opening and extends into the eggplant-shaped bottle.

5. The solid phase extraction device according to claim 4, characterized in that: The liquid receiving assembly also includes a connecting pipe, one end of which is inserted into the eggplant-shaped bottle, and the other end of which is connected to the atmosphere.

6. The solid phase extraction device according to claim 4, characterized in that: The liquid receiving assembly further comprises a control valve, which is arranged at the liquid outlet end of the liquid reservoir to control the flow rate of the liquid flowing into the eggplant-shaped bottle.

7. The solid phase extraction device according to any one of claims 1 to 3, characterized in that: It also includes a telescopic assembly, the telescopic assembly includes a first telescopic rod and a second telescopic rod, the first telescopic rod is connected to the base, and the second telescopic rod is connected to the support frame; A limit block is provided on one of the first telescopic rod and the second telescopic rod, and a plurality of limit holes are provided on the other of the first telescopic rod and the second telescopic rod. The plurality of limit holes are arranged along the length direction of the second telescopic rod, the limit block and the plurality of limit holes match each other, and the limit block is inserted into the limit hole to fix the second telescopic rod.

8. The solid phase extraction device according to any one of claims 1 to 3, characterized in that: The liquid reservoir further comprises a connector, a liquid inlet end of the connector is connected to a liquid outlet end of the first syringe, and a liquid outlet end of the connector is connected to a liquid inlet end of the second syringe; The radial dimension of the liquid inlet end of the connector is greater than the radial dimension of the liquid outlet end of the connector.

9. The solid phase extraction device according to any one of claims 1 to 3, characterized in that: The support frame is a mesh structure; and / or, The support frame is made of elastic material.

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