Pressing blood filter

By designing an integrated pressing blood filter, the three-layer membrane and piston structure are used to achieve plasma filtration and quantitative sampling, solving the problems of complex and noise in existing blood centrifugation technology, and providing a simple and fast plasma separation method.

CN222266738UActive Publication Date: 2024-12-31SHIJIAZHUANG HIPRO BIOTECH
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Patent Information

Application Number
CN202420195186.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-01-26
Publication Date
2024-12-31
Estimated Expiration
2034-01-26

AI Technical Summary

Technical Problem

The existing blood centrifugal technology requires more operations and generates noise, which affects the physical and mental health of the operators and makes it difficult to achieve simple and accurate quantitative separation of plasma.

Method used

Design an integrated pressing blood filter, including a shell, a blood filter device, a pressing device and a sampling device, and realizes plasma filtration and quantitative sampling through a capillary flow channel formed by three layers of membranes, and pressing operations are carried out using piston and pressure plate structures. , use color-changing paper to determine the plasma filling condition.

Benefits of technology

It realizes simple and free separation and quantitative sampling of plasma, convenient and fast operation, and is suitable for small-batch blood sampling.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a pressing blood filter which comprises a shell, a blood filtering device, a pressing device and a sampling device, the blood filtering device, the pressing device and the sampling device are installed on the shell, and after being filtered by the blood filtering device, blood plasma is pressed by the pressing device and then sent into the sampling device to be collected; the shell comprises a lower shell and an upper shell; the blood filtering device comprises a blood filtering pad, a flow channel, a sample adding port and a first observation window; the pressing device comprises a pressing plate and a piston; the sampling device comprises a sampling handle and a capillary tube; the capillary tube faces the flow channel and is communicated with the flow channel outlet; the plasma flow filtering blood pad has the beneficial effects that after the plasma flow filtering blood pad is pressed by the piston, clean plasma flows through the flow channel and enters the capillary tube of the sampling device; when the capillary tube is full of plasma, redundant plasma changes the color of the color-changing paper, the piston is stopped from being pressed, sampling is completed, the operation is free of noise, the sampling operation is integrally completed, convenience and rapidness are achieved, investment is small, and the device is suitable for small-batch blood sampling.
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Description

Technical Field

[0001] The present application belongs to the technical field of blood sampling and testing equipment, and in particular relates to a press blood filter. Background Art

[0002] In the process of biological sample processing, centrifugation is often used to separate or fractionate blood into different layers such as red blood cells, white blood cells and plasma. Blood centrifugation is ubiquitous in the field of medical in vitro diagnostics. Blood is usually drawn from a vein in the arm and then placed in an evacuated collection tube. Blood centrifugation requires a special centrifuge instrument to separate blood at a high speed, which requires more operations and generates a lot of noise, affecting the physical and mental health of the operator. Utility Model Content

[0003] The technical problem to be solved by the present application is to provide a press blood filter with an integrated design, which can separate plasma with simple operation, and the filtered plasma can be directly absorbed by the quantitative capillary to achieve accurate quantification and convenient operation.

[0004] To solve the above problems, this application adopts the following technical solutions:

[0005] A compression blood filter comprises a shell, a blood filtering device, a pressing device and a sampling device installed on the shell. After the plasma is filtered by the blood filtering device, it is pressed by the pressing device and then sent to the sampling device for collection.

[0006] Furthermore, the shell includes a lower shell and an upper shell fixedly connected to the lower shell.

[0007] Furthermore, the blood filter device comprises a blood filter pad arranged on the lower shell and a sample addition port arranged on the upper shell; the blood filter pad comprises three layers: an upper membrane (abutting against the upper shell) - a plasma permeation hole is arranged on the membrane; a middle membrane - a flow channel is arranged on the membrane; the flow channel is connected to the sampling device;

[0008] The lower membrane is the base membrane, which is bonded to the lower shell.

[0009] The three-layer membrane forms a capillary channel to facilitate the absorption of plasma.

[0010] Furthermore, the blood filtering device also includes a first observation window for observing the condition of plasma on the blood filtering pad; the first observation window is located on the upper shell.

[0011] Furthermore, a blood filter pool for storing filtered plasma is also provided on the lower shell below the sample addition port; the blood filter pool is communicated with the flow channel; and the first observation window is located on the upper shell above the blood filter pool.

[0012] Furthermore, the pressing device includes a pressing plate hinged to the lower shell on one side of the blood filter pad and a piston fixedly connected to the pressing plate; one side of the pressing plate is clamped to the lower shell via a locking tongue; and the piston is adapted to the sample addition port.

[0013] Furthermore, a circular arc groove is provided on the lower shell below the pressing plate; when the piston needs to abut against the blood filter pad on the sample addition port, the circular arc groove is used to flip up the pressing plate.

[0014] Furthermore, the sampling device includes a sampling handle engaged with the lower shell and a capillary engaged with the sampling handle; the capillary faces the flow channel and is connected with an outlet of the flow channel.

[0015] Furthermore, a color-changing paper is provided on the blood filter pad near the flow channel outlet; and a second observation window is provided on the upper shell above the color-changing paper.

[0016] Compared with the prior art, the present invention has the following significant beneficial effects:

[0017] The blood filter pad is used to filter the plasma. The filtered plasma enters the blood filter pool. After the piston is pressed, the clean plasma flows through the flow channel and enters the capillary of the sampling device. When the capillary is filled with plasma, the excess plasma changes the color of the color-changing paper. At this time, the piston is stopped and the sampling is completed. This operation is noiseless and the sampling operation is completed in an integrated manner. It is convenient and fast, requires low investment, and is suitable for small batch blood sampling. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 A schematic diagram of the three-dimensional structure of this application;

[0019] Figure 2 It is a schematic diagram of the structure of the flow channel of this application;

[0020] Figure 3 This is a schematic diagram of the installation of color-changing paper;

[0021] Figure 4 It is a schematic diagram of the structure of this application;

[0022] Figure 5 for Figure 4 Sectional view at AA;

[0023] Figure 6 for Figure 5 Enlarged view of H;

[0024] Figure 7 is a schematic diagram of an arc groove;

[0025] Figure 8 It is a schematic diagram of the structure of the lower shell.

[0026] In the accompanying drawings,

[0027] 1-lower housing, 2-pressing plate, 3-piston, 4-first observation window, 5-sample adding port, 6-upper cover, 7-second observation window, 8-limiting block, 9-sampling device;

[0028] 10-color changing paper, 11-blood filter pad, 12-buckle, 111-blood filter pool, 112-flow channel, 113-arc groove. DETAILED DESCRIPTION

[0029] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all of the embodiments. The following description of at least one exemplary embodiment is actually only illustrative and is by no means intended to limit the present application and its application or use. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0030] In addition, it should be noted that the use of terms such as "first" and "second" to limit components is only for the convenience of distinguishing the corresponding components. Unless otherwise stated, the above terms have no special meaning and therefore cannot be understood as limiting the scope of protection of this application.

[0031] Example 1

[0032] like Figure 1-8 As shown,

[0033] A compression blood filter comprises a shell, a blood filtering device, a pressing device and a sampling device 9 installed on the shell. After the plasma is filtered by the blood filtering device, it is pressed by the pressing device and then sent to the sampling device for collection.

[0034] The housing comprises a lower housing 1 and an upper housing 6 fixedly connected to the lower housing 1 .

[0035] The blood filter device comprises a blood filter pad 11 arranged on the lower shell 1 and a sample addition port 5 arranged on the upper shell 6; the blood filter pad 11 comprises three layers: an upper membrane (abutting against the upper shell 6) having a plasma permeation hole on the membrane; a middle membrane having a flow channel 112 on the membrane; the flow channel 112 is connected to the sampling device 9;

[0036] The lower film is the bottom film, which is bonded to the lower shell 1.

[0037] The three-layer membrane forms a capillary channel to facilitate the absorption of plasma;

[0038] The blood filtering device further comprises a first observation window 4 for observing the condition of the plasma on the blood filtering pad 11 ; the first observation window 4 is located on the upper shell 6 .

[0039] like Figure 7 As shown, a blood filter pool 111 for storing filtered plasma is also provided on the middle layer of the blood filter pad 11 below the sample addition port 5; the blood filter pool 111 is connected to the flow channel 112; and the first observation window 4 is located on the upper shell 6 above the blood filter pool 111.

[0040] The pressing device comprises a pressing plate 2 hinged to the lower shell 1 at one side of the blood filter pad 11 and a piston 3 fixedly connected to the pressing plate 2 ; the piston 3 is adapted to the sample addition port 5 .

[0041] like Figure 2 As shown, the sampling device 9 includes a sampling handle engaged with the lower housing 1 and a capillary 91 engaged with the sampling handle; the capillary 91 faces the flow channel 112 and is connected to the outlet of the flow channel 112 .

[0042] like Figure 8 As shown, a buckle 12 is provided on the lower shell 1 , and after the sampling device 9 is inserted into the lower shell 1 , it is prevented from falling out and is locked with the lower shell 1 by the buckle 12 .

[0043] like Figure 1 , 3 As shown in Figure 6, a color-changing paper 10 is provided on the blood filter pad 11 near the outlet of the flow channel 112; a second observation window 7 is provided on the upper shell 6 above the color-changing paper 10 to facilitate observation of the color change of the color-changing paper 10 to determine whether the plasma in the capillary 91 is full.

[0044] The working process of this application,

[0045] The sample is added into the sample adding port 5 , and the blood sample will be absorbed by the blood filter pad 11 . When the sample is seen at the first observation window 4 , the pressing plate 2 is turned over, and the piston 3 is buckled onto the sample adding port 5 .

[0046] The pressure plate 2 is flipped up, and the piston 3 is buckled onto the sample addition port 5. There is a sealed space above the blood filter pad 11, forming a positive pressure to press the plasma into the flow channel 112 through the blood filter pad 11. The plasma flows along the flow channel 112 to the mouth of the capillary 91 and is sucked into the capillary 91. The excess plasma continues to flow toward the mouth of the capillary under the action of the positive pressure until the plasma accumulates and is absorbed by the color-changing paper 10. The color-changing paper 10 changes color after absorbing the plasma, which can be seen by the operator through the second observation window 7, reminding the operator to draw out the capillary 9 and the sampling is completed.

[0047] Example 2

[0048] The structure of this embodiment is roughly the same as that of embodiment 1.

[0049] The difference is that

[0050] like Figure 1 As shown, one side of the pressing plate 2 is engaged with the sampling handle via a locking tongue 8;

[0051] The locking tongue 8 is arranged on the sampling handle, and a notch is arranged on the pressing plate 2; when the piston 3 on the pressing plate 2 is not in use, the pressing plate 2 is in a horizontal position, and the notch of the pressing plate 2 is engaged with the locking tongue 8 to prevent the sampling handle from being pulled out from the lower housing 1 and causing misoperation.

[0052] The beneficial effect of installing the locking tongue 8 is that before the pressing plate 2 is turned up, the notch on the pressing plate 2 clamps the locking tongue 8 on the sampling head handle, making the sampling handle unable to be pulled out, thereby preventing the operator from misoperating and pulling out the capillary 91 without adding a blood sample.

[0053] Example 3

[0054] The structure of this embodiment is roughly the same as that of embodiment 1.

[0055] The difference is that

[0056] like Figure 1 , 7 As shown, an arc groove 113 is provided on the lower shell body 1 below the pressing plate 2; when the piston 3 needs to abut the blood filter pad 11 on the sampling port 5, the arc groove 113 is used to flip up the pressing plate 2, and the piston 3 on the pressing plate 2 presses the blood filter pad 11 through the sampling port 5, so that the plasma passes through the flow channel 112 as quickly as possible and enters the capillary 91 of the sampling device 9.

[0057] The above-mentioned embodiments are described in a relatively detailed and specific manner, expressing the preferred embodiments of the present application. They are only used to illustrate the technical ideas and features of the present application. Their purpose is to enable technicians in this field to understand the contents of the present application and implement them accordingly. However, they are not limited to the present application. The patent scope of the present application cannot be limited only by the embodiments. That is, any equivalent changes or modifications made to the spirit disclosed in the present application, for researchers or technicians in this field, without departing from the structure of the present application, local improvements within the system and changes and transformations between subsystems, etc., are still within the patent scope of the present application.

Claims

1. A press blood filter, characterized in that: It comprises a housing and a blood filtering device, a pressing device and a sampling device (9) mounted on the housing; The housing comprises a lower housing (1) and an upper housing (6) fixedly connected to the lower housing (1); The blood filtering device comprises a blood filtering pad (11) arranged between the lower shell (1) and the upper shell (6), a flow channel (112) arranged on the blood filtering pad (11), and a sample addition port (5) arranged on the upper shell (6); the flow channel (112) is in communication with the sampling device (9).

2. A press blood filter according to claim 1, characterized in that: The blood filtering device further comprises a first observation window (4) for observing the condition of the plasma on the blood filtering pad (11); the first observation window (4) is located on the upper shell (6).

3. A press blood filter according to claim 2, characterized in that: A blood filter pool (111) for storing filtered plasma is also provided on the lower shell (1) below the sample addition port (5); the blood filter pool (111) is in communication with the flow channel (112); and the first observation window (4) is located on the upper shell (6) above the blood filter pool (111).

4. A compression blood filter according to claim 3, characterized in that: The pressing device comprises a pressing plate (2) hingedly connected to the lower shell (1) on one side of the blood filter pad (11) and a piston (3) fixedly connected to the pressing plate (2); one side of the pressing plate (2) is clamped to the lower shell (1) via a locking tongue (8); and the piston (3) is adapted to fit the sample addition port (5).

5. A compression blood filter according to claim 4, characterized in that: A circular arc groove (113) is provided on the lower shell body (1) below the pressing plate (2); when the piston (3) needs to be brought into contact with the blood filter pad (11) on the sample addition port (5), the circular arc groove (113) is used to flip up the pressing plate (2).

6. A compression blood filter according to claim 5, characterized in that: The sampling device (9) comprises a sampling handle clamped to the lower housing (1) and a capillary tube (91) clamped to the sampling handle; the capillary tube (91) faces the flow channel (112) and is in communication with an outlet of the flow channel (112).

7. The compression blood filter according to claim 1, characterized in that: A color-changing paper (10) is provided on the blood filter pad (11) near the outlet of the flow channel (112); and a second observation window (7) is provided on the upper shell (6) above the color-changing paper (10).