Experimental-grade fermentation tank suitable for synthesis and processing of prostaglandin

By designing an experimental-grade fermenter with a shared external constant temperature system, the problem of high cost and inconvenient control of fermenter during the synthesis of large batches of prosts in the prior art is solved, and low-cost, efficient temperature control and convenient operation are achieved.

CN222294024UActive Publication Date: 2025-01-03SHANGHAI FANQIN PHARM TECH CO LTD
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Patent Information

Application Number
CN202420783620.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-16
Publication Date
2025-01-03
Estimated Expiration
2034-04-16

AI Technical Summary

Technical Problem

During the prost synthesis process, existing fermentation tanks are costly and inconvenient to control when culturing large batches of raw materials, especially multiple fermentation tanks require independent control systems, resulting in cost and management difficulties.

Method used

An experimental grade fermentation tank was designed, using an external constant temperature system. Multiple fermentation tanks share a constant temperature system, including a constant temperature sleeve, branch pipe and constant temperature refrigeration and heating module, which conducts hot and cold gases through branch pipes, combining a rectangular frame and groove structure, which is convenient. Extend and control.

Benefits of technology

It realizes low-cost and convenient temperature control, and is suitable for biological laboratories that cultivate raw materials in large batches, reduces equipment costs, and improves operation convenience and control accuracy.

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Abstract

The utility model discloses an experimental level fermentation tank suitable for prost synthesis processing, which comprises a frame, an external constant temperature system and a fermentation tank structure, the cross section of the frame is rectangular, and a plurality of cells are arranged on the inner side of the frame; the outer constant-temperature system comprises a constant-temperature sleeve, a branch pipe and a constant-temperature refrigerating and heating module, a fermentation tank structure can be supported and placed on the inner side of the constant-temperature sleeve, a cavity is formed in the inner wall of the constant-temperature sleeve, and a bottom connector connected with the cavity is formed in the bottom side of the constant-temperature sleeve; the constant-temperature refrigerating and heating module is provided with a box body, a constant-temperature refrigerating unit, a constant-temperature heating unit and a connector, the constant-temperature refrigerating unit and the constant-temperature heating unit are arranged in the box body, the connector is arranged on the front side of the box body and connected with the output side of the constant-temperature refrigerating unit and the output side of the constant-temperature heating unit, one end of a branch pipe is communicated with the connector, and the other end of the branch pipe is connected with a bottom connector in the bottom side of the constant-temperature sleeve. The external constant temperature system disclosed by the utility model can be applied to a biological laboratory needing large-batch culture of raw materials, and the plurality of fermentation tanks share one external constant temperature system, so that the cost is lower, the use is more convenient, and the control is also facilitated.
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Description

Technical Field

[0001] The utility model relates to the field of prostaglandin synthesis and processing, in particular to an experimental-level fermentation tank suitable for prostaglandin synthesis and processing. Background Art

[0002] Prostaglandins are a class of physiologically active unsaturated fatty acids that are widely distributed in various tissues and body fluids. They were first extracted from human semen and can now be prepared by biosynthesis or total synthesis and used as drugs in clinical practice. The basic structure of prostaglandins is prostanoid acid. Natural prostaglandins contain 20 carbon carboxylic acids and hydroxy fatty acids. Their chemical structure and nomenclature are derived from the prostanoid acid molecule.

[0003] In the early stage of prostaglandin production, some raw materials need to be fermented and cultured. In order to ensure the constant temperature culture of internal materials, some fermentation tanks are generally equipped with a constant temperature controller inside, and the temperature is controlled by the constant temperature controller. This method is more convenient for small batches of raw materials, but when culturing large quantities of raw materials, multiple fermentation tanks need to be configured, and each fermentation tank is configured with a set of control systems, which is costly and not easy to control. Therefore, the utility model proposes an experimental-grade fermentation tank suitable for prostaglandin synthesis and processing, which can be used in biological laboratories that need to culture raw materials in large quantities. Multiple fermentation tanks share an external constant temperature system, which has a low cost on the one hand, and the fermentation tank can be expanded according to the number of raw materials to be cultured on the other hand, which is convenient to use and also conducive to control. Utility Model Content

[0004] The purpose of the utility model is to provide an experimental fermentation tank suitable for the synthesis and processing of prostaglandins to solve the problems raised in the above-mentioned background technology.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an experimental-grade fermentation tank suitable for the synthesis and processing of prostaglandins, comprising a frame, an external constant temperature system and a fermentation tank structure, wherein the frame cross-section is rectangular, and a plurality of slots are arranged on the inner side of the frame; the external constant temperature system comprises a constant temperature jacket, a branch pipe and a constant temperature refrigeration and heating module, wherein the fermentation tank structure can be supported and placed on the inner side of the constant temperature jacket, the inner wall of the constant temperature jacket is provided with a cavity, and the bottom side of the constant temperature jacket is provided with a bottom interface connected to the cavity; the constant temperature refrigeration and heating module comprises a box body, a constant temperature refrigeration unit and a constant temperature heating unit installed in the box body, and a joint installed on the front side of the box body and connected to the output sides of the constant temperature refrigeration unit and the constant temperature heating unit, one end of the branch pipe is connected to the joint, and the other end of the branch pipe is connected to the bottom interface on the bottom side of the constant temperature jacket.

[0006] Preferably, a valve is provided on the branch pipe, and the cold and hot gases output by the constant temperature refrigeration and heating module are conducted to the constant temperature jacket through the branch pipe.

[0007] Preferably, the thermostatic sleeve is adapted to the size of the slots inside the frame, and the thermostatic sleeve is placed in the slots with its upper end extending out of the frame.

[0008] Preferably, the fermentation tank structure comprises a tank body, a tank cover and a stirring structure, wherein the outer wall of the tank body is adapted to the inner diameter of the constant temperature jacket, and a detachable tank cover is provided on the top of the tank body.

[0009] Preferably, an observation port and an opening are provided on the tank cover, and the stirring structure comprises a reduction motor and a stirring shaft, wherein the upper end of the stirring shaft is connected to the reduction motor, and the lower end thereof extends into the tank body.

[0010] Compared with the prior art, the beneficial effects of the utility model are:

[0011] The utility model can be applied to biological laboratories that need to culture raw materials in large quantities. Multiple fermentation tanks share an external constant temperature system. On the one hand, the cost is low, and on the other hand, the fermentation tanks can be expanded according to the number of raw materials to be cultured. It is convenient to use and also conducive to control. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0013] Figure 2 It is a schematic diagram of the framework and fermentation tank structure of the utility model.

[0014] In the figure: 1. frame; 2. constant temperature jacket; 3. branch pipe; 4. constant temperature refrigeration and heating module; 5. bottom interface; 6. joint; 7. tank body; 8. tank cover; 9. stirring structure. DETAILED DESCRIPTION

[0015] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0016] In the description of the present invention, it should be noted that the terms "vertical", "up", "down", "horizontal", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0017] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0018] See also Figure 1-2 The utility model provides a technical solution: an experimental-grade fermentation tank suitable for the synthesis and processing of prostaglandins, comprising a frame 1, an external constant temperature system and a fermentation tank structure, wherein the frame 1 is rectangular in cross section, and a plurality of slots are arranged on the inner side of the frame 1; the external constant temperature system comprises a constant temperature jacket 2, a branch pipe 3 and a constant temperature refrigeration and heating module 4, wherein the fermentation tank structure can be supported and placed on the inner side of the constant temperature jacket 2, the inner wall of the constant temperature jacket 2 is provided with a cavity, and the bottom side of the constant temperature jacket 2 is provided with a bottom interface 5 connected to the cavity; the constant temperature refrigeration and heating module 4 comprises a box body, a constant temperature refrigeration unit and a constant temperature heating unit installed in the box body, and a joint 6 installed on the front side of the box body and connected to the output sides of the constant temperature refrigeration unit and the constant temperature heating unit, one end of the branch pipe 3 is connected to the joint 6, and the other end of the branch pipe 3 is connected to the bottom interface on the bottom side of the constant temperature jacket 2.

[0019] In this embodiment, a valve is provided on the branch pipe 3 , and the cold and hot gases output by the constant temperature refrigeration and heating module 4 are conducted to the constant temperature jacket 2 through the branch pipe 3 .

[0020] In this embodiment, the thermostatic sleeve 2 is adapted to the size of the slots inside the frame 1 , and the thermostatic sleeve 2 is placed in the slots with its upper end extending out of the frame 1 .

[0021] In this embodiment, the fermentation tank structure includes a tank body 7, a tank cover 8 and a stirring structure 9, wherein the outer wall of the tank body 7 is adapted to the inner diameter of the constant temperature jacket 2, and a detachable tank cover 8 is provided on the top of the tank body 7.

[0022] In this embodiment, an observation port and an opening are provided on the tank cover 8 , and the stirring structure 9 includes a reduction motor and a stirring shaft, wherein the upper end of the stirring shaft is connected to the reduction motor, and the lower end thereof extends into the tank body 7 .

[0023] In this embodiment, the above-mentioned fermentation tank can be used in biological laboratories that need to culture raw materials in large quantities. Multiple fermentation tanks share an external constant temperature system. On the one hand, the cost is low, and on the other hand, the fermentation tank can be expanded according to the number of raw materials to be cultured. It is convenient to use and also easy to control.

[0024] It is worth noting that the entire device is controlled by a main control button. Since the device matched with the control button is a commonly used device and belongs to the existing mature technology, its electrical connection relationship and specific circuit structure will not be described in detail here.

[0025] Although the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An experimental fermentation tank suitable for the synthesis and processing of prostaglandins, characterized in that: The invention comprises a frame (1), an external constant temperature system and a fermentation tank structure, wherein the frame (1) has a rectangular cross section and a plurality of slots are arranged on the inner side of the frame (1); the external constant temperature system comprises a constant temperature jacket (2), a branch pipe (3) and a constant temperature refrigeration and heating module (4), wherein the inner side of the constant temperature jacket (2) can support and place the fermentation tank structure, the inner wall of the constant temperature jacket (2) is provided with a cavity, and the bottom side of the constant temperature jacket (2) is provided with a bottom interface (5) connected to the cavity; the constant temperature refrigeration and heating module (4) comprises a box body, a constant temperature refrigeration unit and a constant temperature heating unit installed in the box body, and a joint (6) installed on the front side of the box body and connected to the output side of the constant temperature refrigeration unit and the constant temperature heating unit, one end of the branch pipe (3) is connected to the joint (6), and the other end of the branch pipe (3) is connected to the bottom interface on the bottom side of the constant temperature jacket (2).

2. The experimental fermentation tank suitable for prostaglandin synthesis and processing according to claim 1, characterized in that: The branch pipe (3) is provided with a valve, and the cold and hot gases output by the constant temperature refrigeration and heating module (4) are conducted to the constant temperature jacket (2) through the branch pipe (3).

3. The experimental fermentation tank suitable for prostaglandin synthesis and processing according to claim 1, characterized in that: The constant temperature sleeve (2) is adapted to the size of the slot grid inside the frame (1), and the constant temperature sleeve (2) is placed in the slot grid with its upper end extending out of the frame (1).

4. The experimental fermentation tank suitable for prostaglandin synthesis and processing according to claim 1, characterized in that: The fermentation tank structure comprises a tank body (7), a tank cover (8) and a stirring structure (9), wherein the outer wall of the tank body (7) is adapted to the inner diameter of the constant temperature jacket (2), and a detachable tank cover (8) is provided on the top of the tank body (7).

5. The experimental fermentation tank suitable for prostaglandin synthesis and processing according to claim 4, characterized in that: The tank cover (8) is provided with an observation port and an opening, and the stirring structure (9) comprises a reduction motor and a stirring shaft, wherein the upper end of the stirring shaft is connected to the reduction motor and the lower end thereof extends into the tank body (7).