Tangential flow filtering membrane enveloping column uniform distribution device

Abstract

The utility model discloses a tangential flow filter membrane enveloping column uniform distribution device which comprises a main shell, a main feeding hole vertically extending downwards is formed in the middle of the top surface of the main shell, a plurality of transverse discharging through holes are formed in the side wall of the main shell, and the inner ends of the transverse discharging through holes are communicated with the main feeding hole; all the transverse discharging through holes are evenly distributed in the main shell with the central axis of the main shell as the center. The distances between all the transverse discharging through holes and the main feeding hole are consistent, so that materials in the main feeding hole can uniformly flow into all the transverse discharging through holes to flow out, and the materials can uniformly flow into hollow fiber membrane columns or flat membrane bags communicated with the transverse discharging through holes; the material flow of each hollow fiber membrane column or flat sheet membrane bag is equal, the uniformity of the hollow fiber membrane columns or flat sheet membrane bags is ensured, the service lives of all the hollow fiber membrane columns or flat sheet membrane bags are basically consistent, the service life is not too short, and the replacement frequency is reduced.

Description

Technical field:

[0001] The utility model relates to the technical field of biopharmaceuticals, and more specifically to a tangential flow filtration membrane coating column uniform distribution device. Background technology:

[0002] In the biopharmaceutical equipment industry, the linear arrangement structure currently used in the market is generally Figure 1 As shown, a is the material inlet, b, c, d, e, f, g, i, j, k, l are outlets, which are respectively connected to the hollow fiber membrane column or the flat membrane package. The above layout structure has the following defects:

[0003] Since the material enters from the material inlet a and flows out from each branch outlet, and the distances between each branch outlet and the material inlet a are different, there is a sequence, resulting in uneven material flow in the hollow fiber membrane column or flat membrane package connected to each branch outlet, with a small flow at a long distance and a large flow at a short distance, resulting in inconsistent lifespans of the hollow fiber membrane column or flat membrane package, with a short lifespan at a short distance and a relatively long lifespan far from the total flow path, resulting in non-uniform replacement cycles; and since the material flows of all branch outlets are in sequence and their flows are uneven, there is a sequence in the subsequent work process, resulting in low work efficiency. Utility model content:

[0004] The purpose of the utility model is to address the deficiencies of the prior art and to provide a tangential flow filtration membrane package column uniform distribution device, wherein all of its lateral discharge holes are at the same distance from the total feed hole, which can ensure that the material in the total feed hole can evenly flow into all of the lateral discharge holes and flow out, thereby ensuring that the material can evenly flow into the hollow fiber membrane columns or flat membrane packages connected to the lateral discharge holes. The material flow rate of each hollow fiber membrane column or flat membrane package is equal to ensure its uniformity, so that the service life of all hollow fiber membrane columns or flat membrane packages is basically the same, and there will be no excessively short service life, thereby reducing the replacement frequency.

[0005] The technical solutions of the utility model are as follows:

[0006] A tangential flow filtration membrane coating column uniform distribution device comprises a main shell, wherein a main feed hole extending vertically downward is formed in the middle of the top surface of the main shell, and a plurality of lateral discharge holes are formed on the side wall of the main shell, wherein the inner ends of the lateral discharge holes are connected to the main feed hole;

[0007] All the transverse discharge through holes are evenly distributed on the main shell body with the central axis of the main shell body as the center.

[0008] A sleeve connecting portion extending upward is formed in the middle of the top surface of the main shell body, and the top end of the main feed hole extends out of the middle of the top end surface of the sleeve connecting portion.

[0009] A plurality of side protrusions are formed on the side wall of the main shell body to connect the sleeve body, and the outer ends of the transverse discharge through holes extend out of the outer ends of the corresponding middle through holes of the side protrusions to connect the sleeve body.

[0010] The horizontal cross section of the main shell is a regular decagon, which is formed with ten side walls, and a side protrusion connecting sleeve body portion extending outward is formed in the middle of each side wall.

[0011] The material entering from the main feed hole can flow out from ten lateral discharge holes. Since the size, position and connection of all lateral discharge holes are the same as those of the main feed hole, it can be ensured that after all materials enter from the main feed hole, they can flow evenly into all lateral discharge holes and flow out.

[0012] The beneficial effects of the utility model are:

[0013] All of its lateral discharge holes are at the same distance from the total feed hole, which can ensure that the material in the total feed hole can evenly flow into all the lateral discharge holes, thereby ensuring that the material can evenly flow into the hollow fiber membrane columns or flat membrane packages connected to the lateral discharge holes. The material flow rate of each hollow fiber membrane column or flat membrane package is equal, ensuring its uniformity, so that the service life of all hollow fiber membrane columns or flat membrane packages is basically the same, and there will be no excessively short service life, thereby reducing the replacement frequency. Description of the drawings:

[0014] Figure 1 It is a simplified schematic diagram of the existing material flow device;

[0015] Figure 2 It is a structural schematic diagram of the utility model;

[0016] Figure 3 It is a partial top view of the utility model;

[0017] Figure 4 It is a partial cross-sectional view of the utility model;

[0018] Figure 5 A partial cross-sectional view of the utility model from another direction;

[0019] Figure 6 yes Figure 5 A partial enlarged view of . Specific implementation method:

[0020] Example: See Figures 2 to 6As shown, a tangential flow filtration membrane coating column uniform distribution device includes a main shell 10. The horizontal cross-section of the main shell 10 is a regular decagon, which is formed with ten side walls. The middle part of each side wall is formed with a side protrusion connecting sleeve part 14 extending outward. The middle part of the top surface of the main shell 10 is formed with a total feed hole 11 extending vertically downward, and the inner end of the lateral discharge through hole 12 is communicated with the total feed hole 11; all the lateral discharge through holes 12 are evenly distributed on the main shell 10 with the central axis of the main shell 10 as the center.

[0021] A sleeve connecting portion 13 extending upward is formed in the middle of the top surface of the main shell 10 , and the top end of the main feed hole 11 extends out of the middle of the top end surface of the sleeve connecting portion 13 .

[0022] The outer end of the lateral discharge through hole 12 extends out to connect with the outer end of the middle through hole of the corresponding side protrusion of the sleeve body 14 .

[0023] In this structure, the material entering from the main feed hole 11 can flow out from the ten lateral discharge holes 12. Since the size, position and connection of all the lateral discharge holes 12 are the same as those of the main feed hole 11, it can be ensured that after all the materials enter from the main feed hole 11, they can flow evenly into all the lateral discharge holes 12 and flow out. When in use, the side protruding connecting sleeve 14 is generally connected to the hollow fiber membrane column or the flat membrane package, so that the flow rate and flow velocity entering each hollow fiber membrane column or the flat membrane package can be basically the same, ensuring its uniformity, so that the service life of all hollow fiber membrane columns or the flat membrane packages is basically the same, and there will be no excessively short service life, thereby reducing the replacement frequency.

[0024] Furthermore, a plurality of side clamping grooves 131 are formed on the inner wall of the sleeve connecting portion 13, and all the side clamping grooves 131 are evenly distributed on the inner wall of the sleeve connecting portion 13 with the central axis of the sleeve connecting portion 13 as the center, and the side clamping grooves 131 extend downward to the inner side wall of the entire total feed hole 11, and the divider 20 is inserted into the sleeve connecting portion 13 and the total feed hole 11, and the end of the side plate portion of the divider 20 is inserted into the corresponding side clamping groove 131, and all the side plates of the divider 20 divide it into ten feed sub-holes 21, and each feed sub-hole 21 corresponds to and communicates with the inner end of a horizontal discharge hole 12.

[0025] The outer side wall of each side plate portion is close to or in close contact with the inner side wall of the bottom end of the main feed hole 11 between the two corresponding lateral discharge holes 12 .

[0026] The divider 20 includes a central vertical column 22 , and ten side panels are formed on the outer side wall of the central vertical column 22 . All the side panels are evenly distributed on the outer side wall of the central vertical column 22 with the central axis of the central vertical column 22 as the center.

[0027] An annular ring 23 is formed on the outer side wall of the top end of all the side plates, and the bottom surface of the annular ring 23 is pressed against the top surface of the sleeve connecting portion 13 .

[0028] The outer end of the lateral discharge hole 12 is a cylindrical hole section, and the inner end is a conical hole section. The outer end of the conical hole section is connected to the inner end of the cylindrical hole section, and their inner diameters are equal. The diameter of the outer end of the conical hole section is larger than the inner end.

[0029] The cross-sectional area of ​​each side clamping slot 131 is the same. The use of the divider 20 can ensure that the material entering from the sleeve connecting portion 13 is first evenly divided by the divider 20, and then enters the corresponding lateral discharge hole 12 from the side clamping slot 131, which further ensures that the material flowing out of each lateral discharge hole 12 at the same time is the same, that is, the flow rate of the material is consistent, thereby further ensuring that the material flow entering all hollow fiber membrane columns or flat membrane packages is consistent and uniform, so that the service life of all hollow fiber membrane columns or flat membrane packages is basically the same, and there will be no short service life, thereby reducing the replacement frequency.

[0030] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the technical principle of the present invention. These improvements and modifications should also be regarded as the protection scope of the present invention.

Claims

1. A tangential flow filtration membrane coating column uniform distribution device, comprising a main housing (10), characterized in that: A main feed hole (11) extending vertically downward is formed in the middle of the top surface of the main shell (10), and a plurality of lateral discharge holes (12) are formed on the side wall of the main shell (10), and the inner ends of the lateral discharge holes (12) are in communication with the main feed hole (11); All the transverse discharge through holes (12) are evenly distributed on the main shell (10) with the central axis of the main shell (10) as the center.

2. A tangential flow filtration membrane coating column uniform distribution device according to claim 1, characterized in that: A sleeve connecting portion (13) extending upward is formed in the middle of the top surface of the main shell (10), and the top end of the main feed hole (11) extends out of the middle of the top end surface of the sleeve connecting portion (13).

3. A tangential flow filtration membrane coating column uniform distribution device according to claim 2, characterized in that: A plurality of side protrusion connecting sleeve parts (14) are formed on the side wall of the main shell (10), and the outer ends of the transverse discharge through holes (12) extend out of the outer ends of the corresponding middle through holes of the side protrusion connecting sleeve parts (14).

4. A tangential flow filtration membrane coating column uniform distribution device according to claim 1, characterized in that: The main shell (10) has a horizontal cross-section in the form of a regular decagon and is formed with ten side walls. A side protrusion connecting sleeve portion (14) extending outward is formed in the middle of each side wall.

5. The tangential flow filtration membrane coating column uniform distribution device according to claim 2, characterized in that: A plurality of side clamping grooves (131) are formed on the inner wall of the sleeve connecting part (13), and all the side clamping grooves (131) are evenly distributed on the inner wall of the sleeve connecting part (13) with the central axis of the sleeve connecting part (13) as the center. The divider (20) is inserted into the sleeve connecting part (13) and the main feed hole (11), and the end of the side plate of the divider (20) is inserted into the corresponding side clamping groove (131). All the side plates of the divider (20) divide it into ten feed branch through holes (21), and each feed branch through hole (21) corresponds to and communicates with the inner end of a horizontal discharge through hole (12).

6. A tangential flow filtration membrane coating column uniform distribution device according to claim 5, characterized in that: The outer side wall of each side plate portion is close to or in close contact with the inner side wall of the bottom end of the main feed hole (11) between the two corresponding transverse discharge holes (12).

7. A tangential flow filtration membrane coating column uniform distribution device according to claim 5, characterized in that: The divider (20) comprises a central vertical column (22), and ten side panels are formed on the outer wall of the central vertical column (22). All the side panels are evenly distributed on the outer wall of the central vertical column (22) with the central axis of the central vertical column (22) as the center.

8. A tangential flow filtration membrane coating column uniform distribution device according to claim 7, characterized in that: An annular ring (23) is formed on the outer side wall of the top end of all the side plate parts, and the bottom surface of the annular ring (23) is pressed against the top surface of the sleeve connecting part (13).

9. The device for uniformly distributing a tangential flow filtration membrane coating column according to claim 1, characterized in that: The outer end of the lateral discharge hole (12) is a cylindrical hole section, and the inner end is a conical hole section. The outer end of the conical hole section is connected to the inner end of the cylindrical hole section, and the inner diameters thereof are equal. The diameter of the outer end of the conical hole section is larger than that of the inner end.

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