Exosome storage box for medical detection

Abstract

The utility model discloses an exosome storage box for medical detection, which comprises a shell, a condenser arranged on the shell, and a buffer mechanism arranged on the shell, wherein a turning cover is arranged on the shell and is rotationally connected with the shell; the buffer mechanism comprises a plurality of isolation bases arranged on the shell, a plurality of axial sliding blocks symmetrically arranged on the isolation bases and radial sliding blocks arranged on the isolation bases. A container insertion groove is formed in the isolation base; a first spring is arranged on the axial sliding block, and the two ends of the first spring are fixedly connected with the isolation base and the axial sliding block respectively. Second springs are arranged on the radial sliding blocks, and the two ends of the second springs are fixedly connected with the isolation base and the radial sliding blocks correspondingly. Compared with a traditional device, impact force can be absorbed and dispersed in different directions, and the exosome container is protected against damage of external impact.

Description

Technical Field

[0001] The utility model relates to the technical field of exosome storage, and in particular to an exosome storage box for medical detection. Background Art

[0002] Exosomes are a kind of round or oval membrane vesicle structure with a diameter of about 30 to 150 nanometers. It is rich in lipids, proteins / peptides, mRNA, microRNA (miRNA), long non-coding RNA, and complete organelles. With the deepening of research, the application prospects of exosomes in the biomedical field are becoming increasingly broad, and it is expected to provide new methods and ideas for the diagnosis, treatment and prevention of diseases. Exosomes need to be kept at a low temperature during transportation, which can ensure the stability of exosomes during transportation.

[0003] The current prior art CN220221692U discloses a classification storage box for exosomes, including a storage box shell, a sealing cover hinged on one side of the storage box shell, a fixing plate fixed on one side of the storage box shell, and a limiting structure fixed between the sealing cover and the fixing plate; the utility model facilitates the classification, storage and marking of exosome samples through the partition design of the storage box and the identification plate on the top, which can effectively improve the storage efficiency of the samples, and through a separate groove on one side, the storage and retrieval operation will not affect other exosome storage tubes, thereby improving the storage safety, and the magnet and iron sheet on the inside can attract and fix the storage box, which solves the problem that the existing classification storage box does not classify and mark the test tube storage area when in use, and is prone to sample confusion when storing multiple different exosome samples at the same time.

[0004] The following problems may occur when using the above technology:

[0005] (1) Poor shock resistance. The storage box lacks shock-resistant buffering measures and is easily subject to bumps during transportation. The exosome storage tube is subject to impact and will suffer a certain degree of damage, leading to exosome leakage.

[0006] (2) The thermal insulation performance is poor. The storage box lacks thermal insulation and constant temperature measures. The exosomes need to be kept at a low temperature and constant temperature during transportation. At room temperature, exosomes are easily infected by microorganisms such as bacteria and fungi, causing them to become ineffective and deteriorate.

[0007] Therefore, it is necessary to provide an exosome storage box for medical testing to solve the above technical problems. Summary of the invention

[0008] The utility model overcomes the shortcomings of the prior art and provides an exosome storage box for medical detection.

[0009] In order to achieve the above-mentioned purpose, the technical solution adopted by the utility model is: an exosome storage box for medical detection, including a shell, a condenser arranged on the shell, and a buffer mechanism arranged on the shell.

[0010] The shell is provided with a flip cover, and the flip cover is rotatably connected to the shell.

[0011] The buffer mechanism comprises: a plurality of isolation bases arranged on the housing, a plurality of axial sliders symmetrically arranged on the isolation bases, and a radial slider arranged on the isolation bases.

[0012] The isolation base is provided with a container insertion groove; the axial slider is provided with a first spring, and the two ends of the first spring are respectively fixedly connected to the isolation base and the axial slider; the radial slider is provided with a second spring, and the two ends of the second spring are respectively fixedly connected to the isolation base and the radial slider.

[0013] In a preferred embodiment of the utility model, a first heat insulation layer is provided on the flip cover, and the first heat insulation layer is fixedly connected to the flip cover; a second heat insulation layer is provided on the inner wall of the shell, and the second heat insulation layer is fixedly connected to the shell.

[0014] In a preferred embodiment of the utility model, an elastic pressing block is arranged on the first heat insulating layer, and the material of the elastic pressing block is nitrile rubber; the elastic pressing block is fixedly connected to the first heat insulating layer.

[0015] In a preferred embodiment of the utility model, an iron block is arranged on the flip cover, and the iron block is fixedly connected to the flip cover; an electromagnetic lock is arranged on the shell, the iron block matches the position of the electromagnetic lock, and the electromagnetic lock is fixedly connected to the shell.

[0016] In a preferred embodiment of the utility model, the material of the axial slider is nitrile rubber, and the material of the radial slider is nitrile rubber.

[0017] In a preferred embodiment of the present invention, the depth of the container insertion groove is greater than the height of the container, and the diameter of the container insertion slot is greater than the depth of the container.

[0018] In a preferred embodiment of the utility model, an axial sliding groove is provided on the inner wall of the insertion groove, and a plurality of axial sliding blocks are slidably connected to the axial sliding groove.

[0019] In a preferred embodiment of the utility model, a radial sliding groove is provided at the bottom of the insertion groove, and the radial sliding block is slidably connected to the radial sliding groove.

[0020] In a preferred embodiment of the utility model, a cold air delivery hole is provided on the isolation base, the cold air delivery hole passes through the insertion slot, and the width of the cold air delivery hole is greater than the diameter of the container insertion slot.

[0021] In a preferred embodiment of the utility model, the isolation base is made of heat-conducting material, and the condenser is fixedly connected to the isolation base; the isolation base is made of polycarbonate (PC).

[0022] The utility model solves the defects existing in the background technology, and has the following beneficial effects:

[0023] (1) The utility model is provided with a buffer mechanism, in which a first spring and a second spring are provided, and an axial slider and a radial slider in the buffer mechanism are made of shock-absorbing materials; compared with the traditional device, the utility model can absorb and disperse the impact force in different directions, thereby protecting the exosome container from damage caused by external impact.

[0024] (2) The utility model is provided with a first insulation layer and a second insulation layer, as well as a condenser. The first insulation layer and the second insulation layer have good insulation effects to ensure the stability of the internal low-temperature environment, and the condenser is responsible for creating and maintaining this low-temperature environment. Compared with the traditional device, the utility model can maintain a low-temperature environment and reduce the impact of the external environment on the internal temperature of the storage box. This helps to maintain the stability of the internal temperature of the storage box and ensure that the exosomes are stored in a constant low-temperature environment. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] The utility model is further described below in conjunction with the accompanying drawings and embodiments;

[0026] Figure 1 It is a general three-dimensional structural diagram of a preferred embodiment of the utility model;

[0027] Figure 2 It is a half-section diagram of the buffer mechanism of the preferred embodiment of the utility model;

[0028] In the figure: 1. shell; 2. buffer mechanism; 3. flip cover; 4. elastic pressure block; 5. iron block; 6. electromagnetic lock; 7. isolation base; 8. axial slider; 9. radial slider; 10. container insertion slot; 11. first spring; 12. second spring; 13. cold air delivery hole. DETAILED DESCRIPTION

[0029] The present invention will now be further described in detail in conjunction with the accompanying drawings and embodiments. These drawings are simplified schematic diagrams that only illustrate the basic structure of the present invention in a schematic manner, and therefore only show the components related to the present invention.

[0030] like Figure 1As shown, an exosome storage box for medical testing includes a shell 1, a condenser disposed on the shell 1, and a buffer mechanism 2 disposed on the shell 1. The storage box is designed to provide a stable storage environment for exosomes for medical testing. The shell 1 is used as the main structure to provide basic protection; the condenser is used to maintain the low temperature environment inside the storage box to ensure the activity of the exosomes; the buffer mechanism 2 is used to reduce the impact of external shocks on the inside of the storage box and protect the integrity of the exosomes.

[0031] The housing 1 is provided with a flip cover 3 , and the flip cover 3 is rotatably connected to the housing 1 .

[0032] The flip cover 3 is provided with a first heat insulation layer, which is fixedly connected to the flip cover 3; the inner wall of the shell 1 is provided with a second heat insulation layer, which is fixedly connected to the shell 1. The first heat insulation layer and the second heat insulation layer together form a heat insulation system, which effectively reduces the influence of the external environment on the internal temperature of the storage box and keeps the internal temperature stable.

[0033] The first heat insulating layer is provided with an elastic pressing block 4, and the material of the elastic pressing block 4 is selected from nitrile rubber; the elastic pressing block 4 is fixedly connected to the first heat insulating layer. The elastic pressing block 4 is made of nitrile rubber and has good elasticity and durability. When the flip cover 3 is closed, the elastic pressing block 4 can fit tightly on the exosome container, providing additional fixing and buffering effects to prevent the container from moving or vibrating inside the storage box.

[0034] An iron block 5 is provided on the flip cover 3, and the iron block 5 is fixedly connected to the flip cover 3;

[0035] The shell 1 is provided with an electromagnetic lock 6, the iron block 5 matches the position of the electromagnetic lock 6, and the electromagnetic lock 6 is fixedly connected to the shell 1. The iron block 5 and the electromagnetic lock 6 are used in coordination to achieve the locking function of the storage box. When the electromagnetic lock 6 is powered on, the iron block 5 can be attracted to close the flip cover 3 tightly, thereby ensuring the sealing and safety of the storage box.

[0036] like Figure 2 As shown, the buffer mechanism 2 includes: a plurality of isolation bases 7 arranged on the housing 1, a plurality of axial sliders 8 symmetrically arranged on the isolation bases 7, and a radial slider 9 arranged on the isolation bases 7. The design of the buffer mechanism 2 can further reduce the impact of external shock on the inside of the storage box. The isolation base 7 provides basic support, and the axial sliders 8 and radial sliders 9 can absorb and disperse the impact force in different directions, thereby protecting the integrity of the exosome container.

[0037] The material of the axial slider 8 is nitrile rubber, and the material of the radial slider 9 is nitrile rubber; the axial slider 8 and radial slider 9 made of nitrile rubber have good elasticity and wear resistance, and can effectively absorb impact force.

[0038] The isolation base 7 is provided with a container insertion slot 10, the depth of the container insertion slot 10 is greater than the height of the container, and the diameter of the container insertion slot is greater than the diameter of the container. The design of the container insertion slot 10 enables the exosome container to be firmly placed in the storage box to avoid movement or tilting.

[0039] The axial slider 8 is provided with a first spring 11, and the two ends of the first spring 11 are fixedly connected to the isolation base 7 and the axial slider 8 respectively; an axial sliding groove is provided on the inner wall of the insertion groove, and a plurality of the axial sliders 8 are slidably connected to the axial sliding groove. The first spring 11 provides an additional buffering effect for the axial slider 8. When impacted, the spring can deform to absorb part of the impact force. At the same time, the sliding connection of the axial slider 8 in the axial sliding groove enables the slider to move freely within a certain range, further dispersing the impact force.

[0040] The radial slider 9 is provided with a second spring 12, and the two ends of the second spring 12 are fixedly connected to the isolation base 7 and the radial slider 9 respectively; the bottom of the insertion groove is provided with a radial sliding groove, and the radial slider 9 is slidably connected to the radial sliding groove. The second spring 12 provides a similar buffering effect for the radial slider 9. The sliding connection of the radial slider 9 in the radial sliding groove enables the slider to move freely in a direction perpendicular to the axial direction, further enhancing the buffering effect.

[0041] The isolation base 7 is provided with a cold air delivery hole 13, which passes through the insertion slot, and the width of the cold air delivery hole 13 is greater than the diameter of the container insertion slot 10. The design of the cold air delivery hole 13 enables the cold air generated by the condenser to be directly delivered to the surrounding of the exosome container, ensuring that the inside of the container maintains a low temperature environment. The width of the cold air delivery hole 13 is greater than the diameter of the container insertion slot 10, ensuring that the cold air can fully cover the container and improve the cooling effect.

[0042] The isolation base 7 is made of a heat-conducting material, and the condenser is fixedly connected to the isolation base 7; the isolation base 7 is made of polycarbonate (PC). Polycarbonate (PC) is used as the material of the isolation base 7, which has good thermal conductivity and can quickly conduct the cold air generated by the condenser to the surrounding of the exosome container. This design ensures the stability and uniformity of the temperature inside the storage box, which is conducive to maintaining the activity of the exosomes.

[0043] When the utility model is used, the flip cover 3 is rotated to open it from the housing 1; the exosome container is placed in the container insertion groove 10 of the isolation base 7. The exosome container is inserted along the container insertion groove 10, and the fitted radial slider 9 is pushed from the middle to both sides. Under the reaction force of the second spring 12, the symmetrically distributed radial sliders 9 clamp the exosome container from both sides to the middle, and the first spring 11 is compressed by the gravity of the exosome container. The axial slider 8 supports the exosome container under the reaction force of the first spring 11; the flip cover 3 is pushed to close it with the housing 1. Ensure that the elastic pressing block 4 on the flip cover 3 is tightly fitted on the exosome container. Turn on the power of the electromagnetic lock 6, the iron block 5 is attracted by the electromagnetic lock 6, and the flip cover 3 is locked. Start the condenser to create a low temperature environment inside the storage box. When it is necessary to take out the exosome container, first disconnect the power of the electromagnetic lock 6 and unlock the flip cover 3. Open the flip cover 3 and take out the exosome container from the container insertion groove 10.

[0044] The above is based on the ideal embodiment of the utility model. Through the above description, relevant personnel can make various changes and modifications without departing from the technical concept of the utility model. The technical scope of this utility model is not limited to the content in the specification, and the technical scope must be determined according to the scope of the claims.

Claims

1. An exosome storage box for medical testing, comprising a housing (1), a condenser arranged on the housing (1), and a buffer mechanism (2) arranged on the housing (1): characterized in that ； The housing (1) is provided with a flip cover (3), and the flip cover (3) is rotatably connected to the housing (1); The buffer mechanism (2) comprises: a plurality of isolation bases (7) arranged on the housing (1), a plurality of axial sliders (8) symmetrically arranged on the isolation bases (7), and a radial slider (9) arranged on the isolation bases (7); The isolation base (7) is provided with a container insertion groove (10); the axial slider (8) is provided with a first spring (11), and the two ends of the first spring (11) are respectively fixedly connected to the isolation base (7) and the axial slider (8); the radial slider (9) is provided with a second spring (12), and the two ends of the second spring (12) are respectively fixedly connected to the isolation base (7) and the radial slider (9).

2. The exosome storage box for medical testing according to claim 1, characterized in that: A first heat insulation layer is provided on the flip cover (3), and the first heat insulation layer is fixedly connected to the flip cover (3); a second heat insulation layer is provided on the inner wall of the outer shell (1), and the second heat insulation layer is fixedly connected to the outer shell (1).

3. The exosome storage box for medical testing according to claim 2, characterized in that: An elastic pressing block (4) is arranged on the first heat insulating layer, and the material of the elastic pressing block (4) is nitrile rubber; the elastic pressing block (4) is fixedly connected to the first heat insulating layer.

4. The exosome storage box for medical testing according to claim 1, characterized in that: An iron block (5) is provided on the flip cover (3), and the iron block (5) is fixedly connected to the flip cover (3); an electromagnetic lock (6) is provided on the housing (1), and the positions of the iron block (5) and the electromagnetic lock (6) match, and the electromagnetic lock (6) is fixedly connected to the housing (1).

5. The exosome storage box for medical testing according to claim 1, characterized in that: The material of the axial slider (8) is nitrile rubber, and the material of the radial slider (9) is nitrile rubber.

6. The exosome storage box for medical testing according to claim 1, characterized in that: The depth of the container insertion groove (10) is greater than the height of the container, and the diameter of the container insertion slot is greater than the diameter of the container.

7. The exosome storage box for medical testing according to claim 1, characterized in that: An axial sliding groove is provided on the inner wall of the container insertion groove, and a plurality of axial sliding blocks (8) are slidably connected to the axial sliding groove.

8. The exosome storage box for medical testing according to claim 1, characterized in that: A radial sliding groove is provided at the bottom of the container insertion groove, and the radial sliding block (9) is slidably connected to the radial sliding groove.

9. The exosome storage box for medical testing according to claim 1, characterized in that: The isolation base (7) is provided with a cold air delivery hole (13), the cold air delivery hole (13) passes through the insertion slot, and the diameter of the cold air delivery hole (13) is greater than the diameter of the container insertion slot (10).

10. The exosome storage box for medical testing according to claim 1, characterized in that: The condenser is fixedly connected to the isolation base (7), and the isolation base (7) is made of polycarbonate (PC).

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