Bladder water expansion and perfusion device for small experimental animals
By using T-tee and catheter structure in the bladder water dilation device, the fluid pressure is controlled, and the problem of inaccurate perfusion fluid volume is solved, and the accuracy and safety of bladder water dilation is achieved. It is suitable for intra-vesic medication delivery and lavage.
Patent Information
- Application Number
- CN202420016290.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-01-04
- Publication Date
- 2025-01-10
- Estimated Expiration
- 2034-01-04
AI Technical Summary
In the existing bladder water dilation experiment, the amount of perfusion fluid is difficult to accurately control, which can easily lead to incomplete bladder dilation or rupture.
A small experimental animal bladder water dilation perfusion device was designed, using a T-shaped tee, a flat needle and a catheter structure. The liquid pressure was controlled through the height of the liquid column in the suspended outlet pipe, ensuring quantitative perfusion of liquid and achieving bladder water dilation. And calculate the bladder capacity by the difference in fluid capacity.
It realizes the operation, safety and reliability of bladder water expansion, accurate measurement and strong repeatability, avoiding the adverse phenomenon of too small or too large fluid volume, and can also be used for intravesical medication and lavage.
Smart Images
Figure CN222323695U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a medical experimental device, in particular to a bladder water expansion and perfusion device for experimental animals. Background Art
[0002] Bladder hydrodistension is one of the surgical methods for clinical diagnosis and treatment of diseases such as cystitis, so bladder hydrodistension experiments are often performed on small animals in medicine. The existing bladder hydrodistension experiment is to insert a catheter (epidural catheter for anesthesia) into the urethra of a small experimental animal, and then connect a syringe to the catheter to inject a certain amount of normal saline into the bladder. However, since the amount of liquid to be infused is determined based on the experience of the experimental operator, it is very easy for the amount of liquid to be too small, resulting in incomplete bladder expansion of the experimental animal, or too much liquid to cause bladder rupture of the experimental animal. Summary of the invention
[0003] The utility model aims to solve the above technical problems existing in the prior art and provides a bladder water expansion and perfusion device for small experimental animals.
[0004] The technical solution of the utility model is: a small experimental animal bladder water expansion and irrigation device, which is provided with a T-shaped three-way, a flat-head needle and a urinary catheter. The rear end of the urinary catheter passes through the left and right openings of the T-shaped three-way in sequence and is sealed and connected with the left opening through a first pipe connector. The right opening of the T-shaped three-way is connected with a plug through a second pipe connector. The plug has an axial through hole coaxial with the second pipe connector. The rear end head of the urinary catheter passes through the second pipe connector and is tightly inserted in the axial through hole. The needle head of the flat-head needle penetrates into the urinary catheter through the through hole and passes out from the front end head of the urinary catheter. A water inlet hole is arranged on the front end side wall of the urinary catheter. A water outlet hole is arranged on the side wall of the urinary catheter at the lower opening of the T-shaped three-way, and is connected with the water outlet pipe through the lower opening of the T-shaped three-way through a third pipe connector.
[0005] A preferred technical solution is that the first tube connector is a nut, and the nut tightly fixes the sealing gasket sleeved on the urinary catheter at the left opening of the T-shaped tee.
[0006] The preferred technical solution is that a flat-head needle limiting device is provided at the rear end of the plug.
[0007] The utility model can use the height of the liquid column in the suspended water outlet pipe as the pressure reference to quantify the liquid pressure in the bladder of small experimental animals, and achieve the set pressure through continuous liquid flow, thereby completing the bladder water expansion, avoiding the adverse phenomenon caused by too small or too large amount of perfusion liquid; at the same time, the difference in liquid volume before and after the bladder water expansion operation is calculated to obtain the bladder capacity of the experimental animal under the current pressure. Compared with the existing technology, the utility model has the advantages of simple operation, safety and reliability, accurate measurement and strong repeatability, and can also be used for intravesical drug administration and bladder lavage. BRIEF DESCRIPTION OF THE DRAWINGS
[0008] Figure 1 It is a structural schematic diagram of an embodiment of the utility model. DETAILED DESCRIPTION
[0009] The utility model of the small experimental animal bladder water expansion and perfusion device is as follows Figure 1 As shown, a T-shaped tee 1, a flat-head needle 2 and a urinary catheter 3 are provided. The urinary catheter 3 can be replaced with different specifications according to the inner diameter of the urethra of small experimental animals. Its front end is arc-shaped, which is convenient for catheterization operation. There is a small hole in the center of the arc-shaped top for the flat-head needle 2 to pass through. The rear end of the urinary catheter 3 passes through the left and right openings of the T-shaped tee 1 in sequence and is sealed and connected to the left opening through a first tube connector 4. The first tube connector 4 can be a nut. The nut tightly fixes the sealing pad 9 sleeved on the urinary catheter 3 at the left opening of the T-shaped tee 1 to achieve sealing and avoid leakage. The right opening of the T-type tee 1 is connected to the plug 6 through the second tube connector 5. The plug 6 has an axial through hole 6-1 coaxial with the second tube connector 5. The rear end of the catheter 3 passes through the second tube connector 5 and is tightly inserted in the axial through hole 6-1. The needle 2-1 of the flat-head needle 2 penetrates the catheter 3 through the axial through hole 6-1 and passes through the small hole at the front end of the catheter 3. It should usually pass through the front end of the catheter 3 by about 1mm to ensure that the liquid directly enters the bladder. There is a water inlet hole 3-1 on the front side wall of the catheter 3. There is a water outlet hole 3-2 on the side wall of the catheter 3 located at the lower opening of the T-type tee 1. It is connected to the outlet pipe 8 through the third tube connector 7 and the lower opening of the T-type tee 1. The outlet pipe 8 can be a hose or U-shaped pipe for easy hanging. In order to prevent the flat-headed needle 2 from excessively penetrating the front end of the catheter 3 and damaging the bladder of the experimental animal, a flat-headed needle limiting device 10 can be provided at the rear end of the plug 6. The flat-headed needle limiting device 10 can be an elastic hose that can be covered on the needle plug of the flat-headed needle 2 to ensure the air tightness of the device.
[0010] Operation process:
[0011] First, the flat-head needle 2 is pulled out, and the front end of the catheter 3 is inserted into the bladder of the small experimental animal through the urethra of the small experimental animal. Then, the needle 2-1 of the flat-head needle 2 is inserted into the catheter 3 through the axial through hole 6-1 and passes out from the small hole of the front end of the catheter 3. The rear end of the flat-head needle 2 is connected to the suspended physiological saline infusion bag and infusion set. If the water outlet pipe 8 is a hose, it is hung at a certain height to form a U-shaped tube. When the infusion set is turned on, the physiological saline enters the bladder of the small experimental animal through the flat-head needle 2. When the bladder is fully filled, the physiological saline in the bladder will enter the gap between the catheter 3 and the flat-head needle 2 through the water inlet hole 3-1 and enter the water outlet hose 8 through the water outlet hole 3-2 and the lower port of the T-shaped three-way 1 in turn. The height of the liquid column in the water outlet pipe 8 is the pressure reference, which can quantify the liquid pressure in the bladder of the small experimental animal. The bladder water expansion is completed by continuous liquid flow to reach the set pressure. By calculating the difference in the liquid volume in the infusion bag before and after the bladder water expansion operation, the bladder capacity of the experimental animal under the current pressure can be obtained.
Claims
1. A bladder water expansion and perfusion device for small experimental animals, characterized in that: A T-shaped tee (1), a flat-head needle (2) and a urinary catheter (3) are provided. The rear end of the urinary catheter (3) passes through the left and right openings of the T-shaped tee (1) in sequence and is sealedly connected to the left opening through a first pipe connector (4). The right opening of the T-shaped tee (1) is connected to a plug (6) through a second pipe connector (5). The plug (6) has an axial through hole (6-1) coaxial with the second pipe connector (5). The rear end of the urinary catheter (3) passes through the second pipe connector ( 5) is tightly inserted into the axial through hole (6-1), the needle head (2-1) of the flat-head needle (2) passes through the axial through hole (6-1) into the urinary catheter (3) and passes out from the front end of the urinary catheter (3), the front end side wall of the urinary catheter (3) is provided with a water inlet hole (3-1), the side wall of the urinary catheter (3) is located at the lower opening of the T-shaped tee (1) and is connected to the water outlet pipe (8) through the third pipe connector (7).
2. The bladder water expansion and perfusion device for small experimental animals according to claim 1, characterized in that: The first tube connector (4) is a nut, which tightly fixes the sealing gasket (9) sleeved on the urinary catheter (3) at the left opening of the T-shaped tee (1).
3. The bladder water expansion and perfusion device for small experimental animals according to claim 1 or 2, characterized in that: A flat-head needle limiting device (10) is provided at the rear end of the plug (6).