Imaging mechanism of biological chip and imaging equipment of biological chip

By introducing electric mobile stations and coaxial camera components into the biochip imaging mechanism, the problem of difficulty in adjusting the position of biochip in the prior art is solved, and the imaging effect is significantly improved.

CN222337062UActive Publication Date: 2025-01-10LIANGZHUN (HANGZHOU) SCI INSTR CO LTD
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Patent Information

Application Number
CN202420732748.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-10
Publication Date
2025-01-10
Estimated Expiration
2034-04-10

AI Technical Summary

Technical Problem

The existing biochip imaging mechanism cannot adjust the position of the biochip, resulting in poor shooting results.

Method used

An imaging mechanism of biochip is designed, including a base, an electric mobile station and a stage. The electric mobile station drives the movement of the stage to realize the multi-axis position adjustment of the biochip, combining camera, telecentric lens and polarizer. The coaxial setting ensures coaxiality between the biochip and the camera components during shooting.

Benefits of technology

Through the use of electric mobile stations, the multi-axis movement of the biochip is achieved, the coaxial performance of the biochip and camera components is improved, and the imaging effect is significantly improved.

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Abstract

The utility model provides an imaging mechanism of a biological chip and imaging equipment of the biological chip. The imaging mechanism of the biological chip comprises a bearing assembly of the biological chip and a camera assembly; the electric moving table drives the objective table to move relative to the base; the objective table is movably connected to the electric moving table in the horizontal direction and is used for bearing a biochip, and the biochip moves along with the movement of the electric moving table, so that the position of the biochip is conveniently adjusted, multi-axis movement of the biochip is realized, and the coaxiality of the biochip and the camera assembly is conveniently ensured; the telecentric lens is located between the camera and the polaroid, the camera, the telecentric lens and the polaroid face the biochip located on the objective table in the same axial direction, the camera is used for shooting a picture of the biochip, shooting in the coaxial direction is guaranteed, and the coaxial performance of the biochip, the camera, the telecentric lens and the polaroid is improved; and the shooting effect of the imaging mechanism of the biological chip is ensured.
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Description

Technical Field

[0001] The utility model relates to the technical field of imaging equipment of a biochip, in particular to an imaging mechanism of a biochip and an imaging equipment of a biochip. Background Art

[0002] With the development of science and technology, biochips are applied to the electronic field. Biochips are also called DNA chips or gene chips. Biochips are the crystallization of the combination of DNA hybridization probe technology and semiconductor industry technology. In the imaging device of the biochip, the imaging mechanism of the biochip is a part of the imaging device of the biochip.

[0003] In the prior art, the existing imaging mechanism of the biochip includes a base, a stage and a camera, the stage is connected to the base, the camera is arranged on the upper side of the stage, the camera is connected to the base and faces the stage, the stage is used to carry the biochip, and the camera is used to take pictures of the biochip. At this time, the stage is fixed relative to the base, and the biochip cannot be adjusted in position, resulting in poor shooting effect of the existing imaging mechanism of the biochip. Utility Model Content

[0004] The utility model aims to provide an imaging mechanism and an imaging device for a biochip, wherein the bearing assembly of the biochip comprises a base, an electric movable platform and a loading platform; the electric movable platform is located between the base and the loading platform and drives the loading platform to move relative to the base; the loading platform is movably connected to the electric movable platform in a horizontal direction and is used to bear the biochip, the biochip moves with the movement of the electric movable platform so as to adjust the position of the biochip and realize multi-axis movement of the biochip so as to ensure the coaxiality of the biochip and the camera assembly; the camera assembly is located on the upper side of the bearing assembly of the biochip; the camera assembly comprises a camera, a telecentric lens and a polarizing plate; the telecentric lens is located between the camera and the polarizing plate, the camera, the telecentric lens and the polarizing plate are oriented toward the biochip on the loading platform along the same axial direction, the camera is used to take pictures of the biochip, and the shooting is ensured in the coaxial direction, thereby improving the coaxial performance of the biochip, the camera, the telecentric lens and the polarizing plate and ensuring the shooting effect of the imaging mechanism of the biochip.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] An imaging mechanism of a biochip, applied to an imaging device of a biochip; the imaging mechanism of the biochip comprises:

[0007] The biochip carrying component comprises a base, an electric movable platform and a loading platform; the electric movable platform is located between the base and the loading platform and drives the loading platform to move relative to the base; the loading platform is movably connected to the electric movable platform in a horizontal direction and is used to carry the biochip;

[0008] A camera assembly is located on the upper side of the biochip carrier assembly; the camera assembly includes a camera, a telecentric lens and a polarizing plate; the telecentric lens is located between the camera and the polarizing plate, the camera, the telecentric lens and the polarizing plate are oriented along the same axis toward the biochip on the stage, and the camera is used to take pictures of the biochip.

[0009] Optionally, a fixed end of the electric movable platform is connected to an upper side wall of the base, and a movable end of the electric movable platform is connected to a lower side wall of the loading platform.

[0010] Optionally, the loading platform includes a moving part and a loading body, the moving part is located between the lower side wall of the loading body and the moving end of the electric moving platform, and the loading body moves in a horizontal direction under the driving action of the moving part; the moving stroke of the electric moving platform is greater than the moving stroke of the moving part.

[0011] Optionally, the moving member is a manual X-axis moving member, a manual Y-axis moving member and / or a rotating platform.

[0012] Optionally, a positioning groove is provided on the upper side wall of the carrier body, and the positioning groove is used to position the biochip, and the inner side wall of the positioning groove is in contact with the peripheral side wall of the biochip; the two ends of the biochip are respectively provided with a liquid inlet and a liquid outlet; the liquid inlet and the liquid outlet are connected.

[0013] Optionally, the polarizer is located at the lower side of the telecentric lens, and the camera is located at the upper side of the telecentric lens.

[0014] Optionally, the polarizer is connected to a swinging member and swings under the swinging action of the swinging member.

[0015] Optionally, the imaging mechanism of the biochip further includes a light source assembly, which is located between the carrier assembly and the camera assembly of the biochip and illuminates the biochip on the stage.

[0016] Optionally, the light source assembly includes LED white light beads, a diffuse reflection whiteboard, a semi-transmissive and semi-reflective mirror and a transparent window sheet;

[0017] The LED white light lamp beads are used to output white light;

[0018] The diffuse reflection white board diffusely reflects the white light output by the LED white light lamp beads, and reflects the white light to the biochip and the transparent window sheet on the stage through the semi-transmitting and semi-reflecting mirror;

[0019] The transparent window piece is located at the lower side of the camera assembly and is in a transparent state.

[0020] A biochip imaging device comprises the biochip imaging mechanism.

[0021] Compared with the prior art, the beneficial effects of the utility model are:

[0022] The utility model provides an imaging mechanism of a biochip and an imaging device of the biochip. The bearing component of the biochip comprises a base, an electric moving platform and a loading platform. The electric moving platform is located between the base and the loading platform and drives the loading platform to move relative to the base. The loading platform is movably connected to the electric moving platform in a horizontal direction and is used to bear the biochip. The biochip moves along with the movement of the electric moving platform so as to adjust the position of the biochip and realize multi-axis movement of the biochip so as to ensure the coaxiality of the biochip and the camera component. The camera component is located on the upper side of the bearing component of the biochip. The camera component comprises a camera, a telecentric lens and a polarizing plate. The telecentric lens is located between the camera and the polarizing plate. The camera, the telecentric lens and the polarizing plate face the biochip on the loading platform along the same axial direction. The camera is used to take pictures of the biochip, which ensures that the pictures are taken in a coaxial direction, improves the coaxial performance of the biochip, the camera, the telecentric lens and the polarizing plate, and ensures the shooting effect of the imaging mechanism of the biochip. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present application, and those skilled in the art can obtain other drawings based on these drawings without creative work.

[0024] In order to more completely understand the present application and its beneficial effects, the following description will be given in conjunction with the accompanying drawings. In the following description, the same reference numerals represent the same parts.

[0025] Figure 1 A schematic diagram of an imaging mechanism of a biochip according to an embodiment of the present application is shown.

[0026] Figure 2 A front view of an imaging mechanism of a biochip according to an embodiment of the present application is shown.

[0027] Figure 3A cross-sectional view of an imaging mechanism of a biochip according to an embodiment of the present application is shown.

[0028] Figure 4 Shows Figure 3 A partial enlarged view of point A in the middle.

[0029] Figure 5 Shows Figure 3 A partial enlarged view of point B in the middle.

[0030] Reference numerals

[0031] 100. Imaging mechanism of biochip;

[0032] 10. Biochip carrier assembly; 11. Base; 12. Electric moving platform; 13. Loading platform; 131. Moving part; 132. Loading body; 132a. Positioning groove;

[0033] 20. Camera assembly; 21. Camera; 22. Telecentric lens; 23. Polarizer; 231. Swinging piece;

[0034] 30. Light source assembly; 31. LED white light lamp beads; 32. Diffuse reflection whiteboard; 33. Semi-transmissive and semi-reflective mirror; 34. Transparent window piece. DETAILED DESCRIPTION

[0035] The technical solutions in the embodiments of the present application will be described clearly and completely below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work are within the scope of protection of the present application.

[0036] Please refer to the attached Figures 1 to 5 The embodiment of the present application provides an imaging mechanism 100 of a biochip, which is applied to an imaging device of a biochip. The imaging mechanism 100 of the biochip is used to take photos of the biochip. The imaging mechanism 100 of the biochip includes a biochip carrier component 10 and a camera component 20, and the camera component 20 is arranged on the upper side of the biochip carrier component 10.

[0037] In the embodiment of the present application, the biochip supporting component 10 includes a base 11, an electric movable table 12 and a loading table 13; the electric movable table 12 is located between the base 11 and the loading table 13, and drives the loading table 13 to move relative to the base 11; the loading table 13 is movably connected to the electric movable table 12 in the horizontal direction, and is used to carry the biochip. The biochip moves with the movement of the electric movable table 12 to adjust the position of the biochip and realize multi-axis movement of the biochip, so as to ensure the coaxiality of the biochip and the camera assembly 20.

[0038] In the embodiment of the present application, the camera assembly 20 is located on the upper side of the biochip carrier assembly 10; the camera assembly 20 includes a camera 21, a telecentric lens 22 and a polarizer 23; the telecentric lens 22 is located between the camera 21 and the polarizer 23, the camera 21, the telecentric lens 22, and the polarizer 23 are oriented along the same axis toward the biochip on the stage 13, the camera 21 is used to take pictures of the biochip, ensuring that the shooting is done in the coaxial direction, thereby improving the coaxial performance of the biochip, the camera 21, the telecentric lens 22, and the polarizer 23, and ensuring the shooting effect of the imaging mechanism 100 of the biochip.

[0039] The electric movable table 12 is located on the upper side of the base 11, and the stage 13 is located on the upper side of the electric movable table 12. The fixed end of the electric movable table 12 is connected to the upper side wall of the base 11, and the movable end of the electric movable table 12 is connected to the lower side wall of the stage 13, so that the stage 13 can move under the action of the electric movable table 12, so that the stage 13 can drive the biochip to move relative to the base 11, realize multi-axis movement of the biochip, and ensure the coaxiality of the biochip and the camera assembly 20.

[0040] The carrier 13 includes a moving part 131 and a carrier body 132. The moving part 131 is located between the lower side wall of the carrier body 132 and the moving end of the electric moving platform 12. The moving part 131 is connected to the moving end of the electric moving platform 12. The carrier body 132 is connected to the moving part 131. The carrier body 132 moves in a horizontal direction under the driving action of the moving part 131. The carrier body 132 is used to carry the biochip to facilitate further movement of the biochip. The moving stroke of the electric moving platform 12 is greater than the moving stroke of the moving part 131, so as to improve the movement accuracy of the biochip connected to the carrier body 132.

[0041] The moving part 131 is a manual X-axis moving part 131, a manual Y-axis moving part 131 and / or a rotating platform, so that the biochip connected to the carrier body 132 can be moved in multiple directions, thereby facilitating the adjustment of multiple positions of the biochip connected to the carrier body 132, realizing multi-axis movement of the biochip, so as to ensure the coaxiality of the biochip and the camera assembly 20.

[0042] A positioning groove 132a is provided on the upper side wall of the carrier body 132, and the positioning groove 132a is used to position the biochip. The inner side wall of the positioning groove 132a contacts the peripheral side wall of the biochip to ensure the position accuracy of the biochip and the positioning groove 132a; a liquid inlet and a liquid outlet are respectively provided at both ends of the biochip; the liquid inlet and the liquid outlet are connected, and the liquid enters the biochip through the liquid inlet and can be discharged to the external environment through the liquid outlet.

[0043] The polarizing plate 23 is located at the lower side of the telecentric lens 22 , and the camera 21 is located at the upper side of the telecentric lens 22 , so that the camera 21 can photograph the biochip through the telecentric lens 22 and the polarizing plate 23 in sequence.

[0044] The polarizing plate 23 is connected to a swinging member 231 and swings under the swinging action of the swinging member 231 to adjust the position of the polarizing plate 23 , thereby improving the shooting effect of the camera 21 .

[0045] The imaging mechanism 100 of the biochip also includes a light source assembly 30, which is located between the biochip carrier assembly 10 and the camera assembly 20, and illuminates the biochip on the stage 13, so that the brightness of the biochip on the stage 13 is improved by the light source assembly 30, thereby further improving the shooting effect of the camera 21.

[0046] The light source assembly 30 includes an LED white light lamp bead 31, a diffuse reflection whiteboard 32, a semi-transmissive and semi-reflective mirror 33 and a transparent window piece 34; the LED white light lamp bead 31 is used to output white light; the diffuse reflection whiteboard 32 diffusely reflects the white light output by the LED white light lamp bead 31, and reflects the white light to the biochip and the transparent window piece 34 on the stage 13 through the semi-transmissive and semi-reflective mirror 33, so that the white light output by the LED white light lamp bead 31 can be irradiated to the biochip on the stage 13 through the diffuse reflection whiteboard 32, the semi-transmissive and semi-reflective mirror 33 and the transparent window piece 34; the transparent window piece 34 is on the lower side of the camera assembly 20 and is in a transparent state, thereby ensuring the shooting effect of the camera 21.

[0047] In another embodiment, a biochip imaging device includes a biochip imaging mechanism 100, and the biochip imaging mechanism 100 is a part of the biochip imaging device, and the biochip imaging device is used to take pictures of the biochip.

[0048] Compared with the prior art, the beneficial effects of the utility model are:

[0049] The utility model provides an imaging mechanism 100 of a biochip and an imaging device of a biochip. The carrying component 10 of the biochip comprises a base 11, an electric moving platform 12 and a loading platform 13; the electric moving platform 12 is located between the base 11 and the loading platform 13, and drives the loading platform 13 to move relative to the base 11; the loading platform 13 is movably connected to the electric moving platform 12 along a horizontal direction, and is used to carry the biochip. The biochip moves with the movement of the electric moving platform 12, so as to adjust the position of the biochip and realize the multi-axis movement of the biochip, so as to ensure the stability of the biochip and the loading platform 13. The camera assembly 20 is coaxial; the camera assembly 20 is located on the upper side of the biochip carrier assembly 10; the camera assembly 20 includes a camera 21, a telecentric lens 22 and a polarizer 23; the telecentric lens 22 is located between the camera 21 and the polarizer 23, the camera 21, the telecentric lens 22 and the polarizer 23 are oriented along the same axis toward the biochip on the stage 13, the camera 21 is used to take pictures of the biochip, and the coaxial direction is ensured, thereby improving the coaxial performance of the biochip, the camera 21, the telecentric lens 22 and the polarizer 23, and ensuring the shooting effect of the imaging mechanism 100 of the biochip.

[0050] In the above embodiments, the description of each embodiment has its own emphasis. For parts that are not described in detail in a certain embodiment, reference can be made to the relevant descriptions of other embodiments.

[0051] In the description of this application, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more features.

[0052] Specific examples are used herein to illustrate the principles and implementation methods of the present application. The description of the above embodiments is only used to help understand the method and core idea of ​​the present application. At the same time, for technical personnel in this field, according to the idea of ​​the present application, there will be changes in the specific implementation methods and application scope. In summary, the content of this specification should not be understood as a limitation on the present application.

Claims

1. An imaging mechanism of a biochip, characterized in that: An imaging device applied to a biochip; the imaging mechanism of the biochip comprises: The biochip carrying component comprises a base, an electric movable platform and a loading platform; the electric movable platform is located between the base and the loading platform and drives the loading platform to move relative to the base; the loading platform is movably connected to the electric movable platform in a horizontal direction and is used to carry the biochip; A camera assembly is located on the upper side of the biochip carrier assembly; the camera assembly includes a camera, a telecentric lens and a polarizing plate; the telecentric lens is located between the camera and the polarizing plate, the camera, the telecentric lens and the polarizing plate are oriented along the same axis toward the biochip on the stage, and the camera is used to take pictures of the biochip.

2. The imaging mechanism of the biochip according to claim 1, characterized in that: The fixed end of the electric movable platform is connected to the upper side wall of the base, and the movable end of the electric movable platform is connected to the lower side wall of the loading platform.

3. The imaging mechanism of the biochip according to claim 2, characterized in that: The loading platform includes a moving part and a loading body, the moving part is located between the lower side wall of the loading body and the moving end of the electric moving platform, and the loading body moves in a horizontal direction under the driving action of the moving part; the moving stroke of the electric moving platform is greater than the moving stroke of the moving part.

4. The imaging mechanism of the biochip according to claim 3, characterized in that: The moving part is a manual X-axis moving part, a manual Y-axis moving part and / or a rotating platform.

5. The imaging mechanism of the biochip according to claim 3, characterized in that: The upper side wall of the carrier body is provided with a positioning groove, the positioning groove is used to position the biochip, and the inner side wall of the positioning groove is in contact with the peripheral side wall of the biochip; the two ends of the biochip are respectively provided with a liquid inlet and a liquid outlet; the liquid inlet and the liquid outlet are connected.

6. The imaging mechanism of the biochip according to claim 2, characterized in that: The polarizing plate is located at the lower side of the telecentric lens, and the camera is located at the upper side of the telecentric lens.

7. The imaging mechanism of the biochip according to claim 6, characterized in that: The polarizing plate is connected with a swinging member and swings under the swinging action of the swinging member.

8. The imaging mechanism of the biochip according to claim 1, characterized in that: The imaging mechanism of the biochip also includes a light source component, which is located between the carrier component and the camera component of the biochip and illuminates the biochip on the stage.

9. The imaging mechanism of the biochip according to claim 8, characterized in that: The light source assembly includes LED white light beads, a diffuse reflection whiteboard, a semi-transmissive and semi-reflective mirror and a transparent window sheet; The LED white light lamp beads are used to output white light; The diffuse reflection white board diffusely reflects the white light output by the LED white light lamp beads, and reflects the white light to the biochip and the transparent window sheet on the stage through the semi-transmitting and semi-reflecting mirror; The transparent window piece is located at the lower side of the camera assembly and is in a transparent state.

10. A biochip imaging device, characterized in that: An imaging mechanism comprising a biochip as described in any one of claims 1 to 9.