Heatable C57 mouse tail vein injection auxiliary device

Abstract

The utility model relates to the technical field of caudal vein injection, and discloses a heatable C57 mouse caudal vein injection auxiliary device which comprises an operation table, an auxiliary tube body arranged on the upper end surface of the operation table, an adhesive tape adhered to the outer surface of the auxiliary tube body, two ends of the adhesive tape adhered to the upper end surface of the operation table, and the auxiliary tube body fixed on the upper end surface of the operation table through the adhesive tape. A heater is arranged on the outer surface of one end away from the adhesive tape through the auxiliary pipe body. According to the heatable C57 mouse tail intravenous injection auxiliary device, by arranging the auxiliary pipe body, fixing of a mouse and intravenous injection are facilitated, the mouse can conveniently enter the auxiliary pipe body through the large pipe opening by forming the large pipe opening, it is guaranteed that normal breathing of the mouse is not limited by arranging the small pipe opening, the auxiliary pipe body is made of a non-transparent silica gel material, and the auxiliary pipe body is made of a non-transparent silica gel material. And the device accords with the characteristic that mice like drilling, and is convenient to clean and recycle.

Description

Technical Field

[0001] The utility model relates to the technical field of tail vein injection, in particular to a heatable C57 mouse tail vein injection auxiliary device. Background Art

[0002] Mouse tail vein injection is a common animal experimental technique used to inject drugs, gene vectors and other substances into mice for various biomedical research.

[0003] At present, in common laboratory animal experiments involving tail vein injection of C57 mice, the mouse is first fixed on the injection table using a mouse fixer, and the tail is soaked in warm water to dilate its blood vessels. Then, the experimenter usually places the mouse in the palm of his left hand, fixes the mouse's tail with his fingers, and injects by holding the syringe with his right hand.

[0004] Since the experimental operator grabs and fixes the mice by hand for tail vein injection, the mice may have a stress response, which may cause changes in the hormone levels in the mice within a short period of time, affecting the accuracy of the detection indicators after subsequent intravenous injection; the instability of manual operation may lead to mistakes or injuries during the injection process; there is a risk of being stabbed by sharp objects such as needles during manual grabbing and injection, which also poses a potential threat to the safety of the operator. The method of making an opening in the front of the centrifuge tube, making a hole in the screw cap at the back, putting the mouse in, and passing the tail through the hole in the cap before operating also has problems such as different body lengths of mice, inability to fix the centrifuge tube, and easy contamination and damage to experimental equipment. Therefore, it is necessary to provide a heatable C57 mouse tail vein injection auxiliary device to solve the above problems. Utility Model Content

[0005] In view of the deficiencies in the prior art, the utility model provides a heatable C57 mouse tail vein injection auxiliary device, which solves the problems mentioned in the above background.

[0006] The utility model provides the following technical solution: a heatable C57 mouse tail vein injection auxiliary device, comprising an operating table, an auxiliary tube body is arranged on the upper end surface of the operating table, adhesive tape is adhered to the outer surface of the auxiliary tube body, both ends of the adhesive tape are adhered to the upper end surface of the operating table, the auxiliary tube body is fixed to the upper end surface of the operating table by the adhesive tape, and a heater is arranged on the outer surface of one end of the auxiliary tube body away from the adhesive tape.

[0007] Preferably, the auxiliary tube body has a large tube opening at one end close to the heater, and the auxiliary tube body has a small tube opening at one end away from the large tube opening which shrinks inwards.

[0008] Preferably, the diameter of the small tube opening of the auxiliary tube body is 1.5 cm, and the diameter of the large tube opening is 3 cm.

[0009] Preferably, the auxiliary tube body is 7 cm long and is made of opaque silicone material.

[0010] Preferably, the heater is used to heat the auxiliary tube body, and the heating temperature of the heater is 40°C-45°C.

[0011] Compared with the prior art, the utility model has the following beneficial effects:

[0012] 1. The heatable C57 mouse tail vein injection auxiliary device is convenient for fixing mice and performing intravenous injection by providing an auxiliary tube body. The large tube opening is convenient for mice to enter the auxiliary tube body through the large tube opening. The small tube opening is provided to ensure that the mice can breathe normally without restriction. The auxiliary tube body is made of opaque silicone material, which conforms to the characteristics of mice that like to burrow, and is easy to clean and recycle.

[0013] 2. The heatable C57 mouse tail vein injection auxiliary device has a simple manufacturing process and is easy to produce. By setting a heater, the auxiliary tube body can be effectively heated, thereby fully exposing the tail vein of the mouse inside the auxiliary tube body to facilitate injection. The auxiliary tube body isolates and separates the mouse inside the tube from the outside of the tube, which complies with the concept of sterility and solves the safety and infection risks such as mouse stress and scratches and bites caused by directly grabbing mice by hand in the traditional mode. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a schematic diagram of the overall structure of the heatable C57 mouse tail vein injection auxiliary device of the utility model;

[0015] Figure 2 This is a schematic diagram of the side structure of the heatable C57 mouse tail vein injection auxiliary device of the utility model;

[0016] Figure 3 This is a schematic diagram of the top view of the heatable C57 mouse tail vein injection auxiliary device of the utility model;

[0017] Figure 4 This is a schematic diagram of the back structure of the heatable C57 mouse tail vein injection auxiliary device of the utility model;

[0018] Figure 5 It is a schematic diagram of the structure of the utility model when the adhesive tape is not installed.

[0019] In the figure: 1. operating table; 2. auxiliary pipe body; 201. small pipe opening; 202. large pipe opening; 3. adhesive tape; 4. heater. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0021] See also Figure 1-5 A heatable C57 mouse tail vein injection auxiliary device comprises an operating table 1, an auxiliary tube body 2 is arranged on the upper end surface of the operating table 1, an adhesive tape 3 is adhered to the outer surface of the auxiliary tube body 2, both ends of the adhesive tape 3 are adhered to the upper end surface of the operating table 1, the auxiliary tube body 2 is fixed to the upper end surface of the operating table 1 by the adhesive tape 3, and a heater 4 is arranged on the outer surface of one end of the auxiliary tube body 2 away from the adhesive tape 3.

[0022] Among them, a large tube opening 202 is opened at one end of the auxiliary tube body 2 close to the heater 4, and the end of the auxiliary tube body 2 away from the large tube opening 202 is contracted inward and opened with a small tube opening 201. The large tube opening 202 facilitates mice to enter the auxiliary tube body 2 through the large tube opening 202, and the small tube opening 201 is provided to ensure that the mice can breathe normally without restriction.

[0023] Among them; the small tube mouth 201 of the auxiliary tube body 2 has a diameter of 1.5 cm, the large tube mouth 202 has a diameter of 3 cm, and the auxiliary tube body 2 is 7 cm long. The auxiliary tube body 2 is made of opaque silicone material, which conforms to the characteristics of mice that like to dig holes, is easy to clean and recycle, and the auxiliary tube body 2 is 7 cm long, which conforms to the general size and length of C57 mice. The mice in the tube are isolated from the outside of the tube, which conforms to the concept of sterility and solves the safety and infection risks such as mouse stress and scratches and bites caused by directly grabbing mice by hand in the traditional mode.

[0024] Among them; the heater 4 is used to heat the auxiliary tube body 2, and the heating temperature of the heater 4 is 40℃-45℃. By providing the heater 4, the auxiliary tube body 2 can be effectively heated, thereby achieving full exposure of the mouse tail vein of the mouse inside the auxiliary tube body 2, which is convenient for injection, simple to operate, saves time and effort, and reduces the labor intensity of the staff.

[0025] Working principle: aim the large tube opening 202 of the auxiliary tube body 2 at the mouse's head. The auxiliary tube body 2 is made of opaque silicone material, which conforms to the characteristics of mice that like to dig holes, and attracts mice to drill into the device tube through the large tube opening 202. According to the general size and body length of C57 mice, the small tube opening 201 of the auxiliary tube body 2 is designed to have a diameter of 1.5 cm, the large tube opening 202 has a diameter of 3 cm, and the auxiliary tube body 2 is 7 cm long. After the mouse enters the auxiliary tube body 2, the mouse body is fixed inside the auxiliary tube body 2. By setting the small tube opening 201, the mouse can breathe normally without restriction and its tail is fully exposed to the rear hole.

[0026] Further, the experimental operator starts the heater 4 for heating. After the silicone device is heated, the mouse tail vein is fully exposed. The heating temperature is more appropriately 40°C-45°C. The operation is performed after the mouse tail vein is fully exposed. This can not only ensure the accuracy and standardization of the tail vein injection operation, but also greatly reduce the short-term hormone secretion in the body that may be caused by stress in the mouse, greatly improving the accuracy of the detection indicators after injection. At the same time, the device is fixed to the upper surface of the operating table 1 by the tape 3, freeing the hands of the experimental operator while also greatly improving the safety of the experiment.

[0027] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A heatable C57 mouse tail vein injection assisting device, characterized in that: The operating table (1) comprises an auxiliary tube body (2) arranged on the upper surface of the operating table (1), an adhesive tape (3) being adhered to the outer surface of the auxiliary tube body (2), both ends of the adhesive tape (3) being adhered to the upper surface of the operating table (1), the auxiliary tube body (2) being fixed to the upper surface of the operating table (1) by the adhesive tape (3), and a heater (4) being arranged on the outer surface of one end of the auxiliary tube body (2) away from the adhesive tape (3).

2. A heatable C57 mouse tail vein injection auxiliary device according to claim 1, characterized in that: The auxiliary tube body (2) has a large tube opening (202) at one end close to the heater (4), and the auxiliary tube body (2) has a small tube opening (201) at one end away from the large tube opening (202).

3. A heatable C57 mouse tail vein injection auxiliary device according to claim 2, characterized in that: The small tube opening (201) of the auxiliary tube body (2) has a diameter of 1.5 cm, and the large tube opening (202) has a diameter of 3 cm.

4. A heatable C57 mouse tail vein injection auxiliary device according to claim 1, characterized in that: The auxiliary tube body (2) is 7 cm in length and is made of opaque silicone material.

5. A heatable C57 mouse tail vein injection auxiliary device according to claim 1, characterized in that: The heater (4) is used to heat the auxiliary tube body (2), and the heating temperature of the heater (4) is 40° C.-45° C.

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