Online beagle bile collecting device
By designing the beagle bile online collection device, safe collection of bile is achieved using components such as wrapping cloth and gallbladder cannula, the problem of vulnerability and long-term care of the bile collection device is solved, and the reliability of the experiment and the life of animals is improved. condition.
Patent Information
- Application Number
- CN202420755724.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-12
- Publication Date
- 2025-01-17
- Estimated Expiration
- 2034-04-12
AI Technical Summary
The existing bile collection device is prone to damage and shedding of common bile ducts in the experiment, and requires long-term care, which affects the reliability of the experimental results and the normal life of animals. The digestive system between rats and humans is very different. Extrapolated research results There is uncertainty.
A beagle bile online collection device is designed, including a chassis, liquid extraction assembly and collection assembly, which realizes bile through packaging cloth, diversion hose, one-way valve, gallbladder cannula, Velcro and collection bags. Safe, long-term online collection and allow dogs to move normally in cages to avoid shedding and long-term care.
The safe and long-term online collection of bile is achieved, which reduces discomfort with beagles and the care needs of the experimenters, improves the reliability of the experiment and the living conditions of the animals, and avoids the fall of the gallbladder cannula.
Smart Images

Figure CN222357813U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of pharmacokinetic experiments, in particular to an online bile collection device for beagle dogs. Background Art
[0002] Bile is a digestive fluid secreted by the liver and bile ducts; enterohepatic circulation refers to the process in which substances excreted by the liver (including drugs, endogenous substances and toxins, etc.) enter the intestine with bile and are reabsorbed and re-enter the systemic circulation through the liver. Current studies have found that atorvastatin, colchicine and other drugs in drugs as well as endogenous substances (such as bile acids and toxic substances such as lead and organochlorine compounds) all have enterohepatic circulation. The presence of drug ETC can make the drug appear bimodal or multimodal, which helps to improve the bioavailability of the drug and enhance the efficacy; however, the long-term presence and accumulation of endogenous substances and toxic substances ETC in the human body will cause harm. Bile drainage can not only treat biliary obstruction, but also be used as a method to block enterohepatic circulation in poisoning treatment, directly excreting toxins excreted through bile, blocking the process of toxins entering the intestine through bile secretion and then being reabsorbed into the body again, ultimately reducing the load of toxic substances in the body and restoring the body to normal physiological state.
[0003] In the past, bile excretion experiments were mostly conducted on rats. The rats were fixed and anesthetized, the abdominal cavity was opened, the common bile duct was separated, and a polyethylene drainage tube was inserted to study bile excretion. The polyethylene drainage tube is hard in texture, and although it is easy to insert into the common bile duct, it is easy to damage the common bile duct. The rats need to be fixed all the time during the experiment, and only short-term bile excretion can be studied. At the same time, the inability of rats to move normally will affect bile secretion and excretion, leading to biased experimental results, which is also contrary to animal ethics and the "3R" principle. In addition, rats are rodents, and their digestive systems are quite different from those of humans. There is greater uncertainty when the research results are extrapolated to humans. Dogs are more closely related to humans. There are also bile excretion experiments using beagles as experimental animals. The beagles are generally anesthetized, the abdominal cavity is opened, the common bile duct is separated and a silicone / latex T-type drainage tube is inserted to study bile excretion. The silicone / latex T-type drainage tube is soft and will not damage the common bile duct, but it is easy to fall off. Dogs are active and active, which can easily cause it to fall off. In addition, it takes a long time to be cared for during bile collection, which wastes manpower. Therefore, a beagle bile online collection device is proposed. Utility Model Content
[0004] The technical problem to be solved by the utility model is to overcome the existing defects and provide an online bile collection device for beagle dogs, which can avoid falling off and long-term care, and can effectively solve the problems in the background technology.
[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an online bile collection device for beagle dogs, comprising a bottom plate and a liquid extraction component;
[0006] A cage is fixed at the upper end of the chassis, an opening is opened in the middle of the cage, a fixing ring is fixed inside the opening, and a connecting assembly is installed at the upper end of the cage;
[0007] The liquid extraction component includes a wrapping cloth, a diversion hose, a one-way valve, a gallbladder cannula, a Velcro tape and a Velcro mother tape. The cage is provided with a wrapping cloth inside, the lower end of the connecting component is connected to the wrapping cloth, a fixing hole is opened in the middle of the wrapping cloth, the inside of the fixing hole is fixed with a diversion hose, a one-way valve is installed on the circumferential surface of the diversion hose, a gallbladder cannula is fixed to the lower end of the diversion hose, two corresponding Velcro tapes are fixed to the lower end of the left side of the wrapping cloth, and two corresponding Velcro mother tapes are fixed to the right side of the wrapping cloth, the Velcro tape and the Velcro mother tape cooperate with each other, and a collecting component is installed on the right side of the wrapping cloth, and the bile of the beagle is extracted by setting the liquid extraction component.
[0008] Furthermore, the collecting assembly includes a collecting bag, a storage plastic bag, a zipper and a sealing cover; the collecting bag is fixed to the right side of the wrapping cloth; the right end of the diversion hose is fixed to the inside of a liquid inlet provided on the surface of the collecting bag; a storage plastic bag is fixed to the right side of the collecting bag; the upper end of the storage plastic bag is connected to the collecting bag via a zipper; a sealing cover is clamped inside a discharge port provided at the front end of the collecting bag; and bile is stored by providing a collecting assembly.
[0009] Furthermore, the connecting component includes a U-shaped sliding frame, a guide ring and a connecting rope. The upper end of the cage is slidably connected to the U-shaped sliding frame. The upper end of the cage is provided with an annular groove. The inside of the annular groove is slidably connected to the guide ring. The guide ring is fixed inside the U-shaped sliding frame. The surface of the U-shaped sliding frame is fixed with a connecting rope. The lower end of the connecting rope is fixed to the upper side of the wrapping cloth. The wrapping cloth is connected to the cage by setting the connecting component.
[0010] Furthermore, a mounting hole is provided at the front end of the cage surface, a rotating shaft is rotatably connected inside the mounting hole, a baffle is fixed on the circumferential surface of the rotating shaft, and the beagle is limited by setting the baffle.
[0011] Furthermore, a sliding opening is opened on the circumferential surface of the fixed ring, and a U-shaped plate is slidably connected inside the sliding opening. The U-shaped plate is clamped on the upper side of the baffle, and a spring is fixed on the upper side of the sliding opening. The baffle is fixed by setting the U-shaped plate.
[0012] Furthermore, a storage box is fixed to the upper end of the chassis, and two corresponding storage slots are provided on the upper side of the storage box. The water and food required by the Baoding dog on a daily basis are stored by providing the storage box and the two storage slots.
[0013] Compared with the prior art, the beneficial effects of the utility model are:
[0014] By setting up the extraction component, the gallbladder cannula is connected to the gallbladder of the beagle dog through surgery during use. After the operation, the wrapping cloth is wrapped on the beagle dog through the Velcro sub-stick and the Velcro mother-stick. After wrapping, the bile in the gallbladder of the beagle dog can be drawn into the collection bag through the gallbladder cannula for collection. During the whole collection process, the beagle dog is placed in a cage. In this case, the bile of the beagle dog can be collected online for a long time without affecting the normal drinking, eating and activities of the animal. The user does not need to take care of it for a long time, and the wrapping cloth can prevent the gallbladder cannula from falling off. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] Figure 1 This is a schematic diagram of the front structure of the utility model;
[0016] Figure 2 This is a schematic diagram of the structure of the liquid pumping component of the utility model;
[0017] Figure 3 This is a schematic diagram of the storage box structure of the utility model.
[0018] In the figure: 1 chassis, 2 cage, 3 extraction assembly, 31 wrapping cloth, 32 diversion hose, 33 one-way valve, 34 gallbladder cannula, 35 Velcro, 36 Velcro, 4 collection assembly, 41 collection bag, 42 storage plastic bag, 43 zipper, 44 sealing cover, 5 connection assembly, 51 U-shaped sliding frame, 52 guide ring, 53 connecting rope, 6 storage box, 7 storage slot, 8 rotating shaft, 9 baffle, 10 U-shaped plate, 11 spring, 12 fixing ring. DETAILED DESCRIPTION
[0019] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0020] See also Figure 1-3 , This embodiment provides a technical solution: an online bile collection device for beagle dogs, comprising a chassis 1 and a liquid extraction component 3, wherein the liquid extraction component 3 is provided to extract the bile of the beagle dogs;
[0021] Among them, a cage 2 is fixed to the upper end of the chassis 1, an opening is opened in the middle of the cage 2, a fixing ring 12 is fixed inside the opening, a connecting assembly 5 is installed on the upper end of the cage 2, the connecting assembly 5 includes a U-shaped sliding frame 51, a guide ring 52 and a connecting rope 53, the upper end of the cage 2 is slidably connected to the U-shaped sliding frame 51, an annular groove is opened at the upper end of the cage 2, the inside of the annular groove is slidably connected to the guide ring 52, the guide ring 52 is fixed to the inside of the U-shaped sliding frame 51, a connecting rope 53 is fixed to the surface of the U-shaped sliding frame 51, the lower end of the connecting rope 53 is fixed to the upper side of the wrapping cloth 31, and the wrapping cloth 31 is connected to the cage 2 by setting the connecting assembly 5;
[0022] Among them, the liquid extraction component 3 includes a wrapping cloth 31, a diversion hose 32, a one-way valve 33, a gallbladder cannula 34, a Velcro 35 and a Velcro mother patch 36. The wrapping cloth 31 is arranged inside the cage 2, and the lower end of the connecting component 5 is connected to the wrapping cloth 31. A fixing hole is opened in the middle of the wrapping cloth 31, and the diversion hose 32 is fixed inside the fixing hole. A one-way valve 33 is installed on the circumferential surface of the diversion hose 32, and a gallbladder cannula 34 is fixed at the lower end of the diversion hose 32. Two corresponding Velcro 35 are fixed to the lower end of the left side of the wrapping cloth 31, and two corresponding Velcro mother patches 36 are fixed to the right side of the wrapping cloth 31. The Velcro 35 and the Velcro mother patch 36 cooperate with each other;
[0023] A collecting assembly 4 is installed on the right side of the wrapping cloth 31 to store bile. The collecting assembly 4 includes a collecting bag 41, a storage plastic bag 42, a zipper 43 and a sealing cover 44. The collecting bag 41 is fixed on the right side of the wrapping cloth 31, and the right end of the diversion hose 32 is fixed to the inside of the liquid inlet set on the surface of the collecting bag 41. The storage plastic bag 42 is fixed on the right side of the collecting bag 41. The upper end of the storage plastic bag 42 is connected to the collecting bag 41 through a zipper 43, and the sealing cover 44 is clamped inside the discharge port set at the front end of the collecting bag 41.
[0024] The front end of the cage 2 is provided with a mounting hole, the interior of the mounting hole is rotatably connected with a rotating shaft 8, a baffle 9 is fixed on the circumferential surface of the rotating shaft 8, and the baffle 9 is provided to limit the position of the beagle.
[0025] Among them: a sliding opening is opened on the circumferential surface of the fixed ring 12, and a U-shaped plate 10 is slidably connected inside the sliding opening. The U-shaped plate 10 is clamped on the upper side of the baffle 9. A spring 11 is fixed on the upper side of the U-shaped plate 10. The spring 11 is fixed on the upper side of the sliding opening. The baffle 9 is fixed by setting the U-shaped plate 10.
[0026] Wherein: a storage box 6 is fixed at the upper end of the chassis 1, and two corresponding storage slots 7 are provided on the upper side of the storage box 6. The storage box 6 and the two storage slots 7 are provided to store water and food needed by the Baoding dog on a daily basis.
[0027] The working principle of the utility model is as follows:
[0028] During use, the water and food needed by the dog are first stored in the two storage tanks 7. After storage, the gallbladder cannula 34 is connected to the gallbladder of the beagle through surgery. After surgery, the wrapping cloth 31 is tightly wrapped around the beagle through the Velcro 35 and the Velcro 36. After wrapping, the bile in the gallbladder of the beagle can be drawn into the collection bag 41 through the gallbladder cannula 34 for collection.
[0029] Before collecting, ice cubes are placed inside the storage plastic bag 42 and then the zipper is closed. In this case, the ice cubes will cool the collected bile during the collection process, and the activity of active enzymes in the bile will be reduced after cooling, which is more conducive to the preservation of the bile;
[0030] During the entire collection process, the beagle is placed in the cage 2, and the U-shaped sliding frame 51, the guide ring 52 and the connecting rope 53 can secure the beagle, while allowing the beagle to move normally in the cage 2. In this case, the bile of the beagle can be collected online for a long time without affecting the animal's normal drinking, eating and activities, and the user does not need to take care of it for a long time. At the same time, the wrapping cloth 31 can prevent the gallbladder catheter 34 from falling off.
[0031] The above description is only an embodiment of the present invention, and does not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made by using the contents of the specification and drawings of the present invention, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.
Claims
1. A beagle bile online collection device, characterized in that: It comprises a chassis (1) and a liquid extraction component (3); A cage (2) is fixed to the upper end of the chassis (1), an opening is provided in the middle of the cage (2), a fixing ring (12) is fixed inside the opening, and a connecting assembly (5) is installed at the upper end of the cage (2); The liquid extraction component (3) comprises a wrapping cloth (31), a diversion hose (32), a one-way valve (33), a gallbladder cannula (34), a Velcro (35) and a Velcro (36). The cage (2) is provided with a wrapping cloth (31). The lower end of the connecting component (5) is connected to the wrapping cloth (31). A fixing hole is provided in the middle of the wrapping cloth (31). The diversion hose (32) is fixed inside the fixing hole. The one-way valve (33) is installed on the circumferential surface of the diversion hose (32). The gallbladder cannula (34) is fixed at the lower end of the diversion hose (32). Two corresponding Velcro (35) are fixed at the lower end of the left side of the wrapping cloth (31). Two corresponding Velcro (36) are fixed at the right side of the wrapping cloth (31). The Velcro (35) and the Velcro (36) cooperate with each other. The collecting component (4) is installed on the right side of the wrapping cloth (31).
2. The device for collecting bile online for beagle dogs according to claim 1, characterized in that: The collecting assembly (4) comprises a collecting bag (41), a storage plastic bag (42), a zipper (43) and a sealing cover (44); the collecting bag (41) is fixed to the right side of the wrapping cloth (31); the right end of the diversion hose (32) is fixed to the inside of a liquid inlet provided on the surface of the collecting bag (41); the storage plastic bag (42) is fixed to the right side of the collecting bag (41); the upper end of the storage plastic bag (42) is connected to the collecting bag (41) via a zipper (43); and the sealing cover (44) is clamped to the inside of a discharge port provided at the front end of the collecting bag (41).
3. The device for collecting bile online for beagle dogs according to claim 1, characterized in that: The connecting assembly (5) comprises a U-shaped sliding frame (51), a guide ring (52) and a connecting rope (53); the upper end of the cage (2) is slidably connected to the U-shaped sliding frame (51); the upper end of the cage (2) is provided with an annular groove; the interior of the annular groove is slidably connected to the guide ring (52); the guide ring (52) is fixed inside the U-shaped sliding frame (51); the surface of the U-shaped sliding frame (51) is fixed with a connecting rope (53); the lower end of the connecting rope (53) is fixed to the upper side of the wrapping cloth (31).
4. The device for collecting bile online for beagle dogs according to claim 1, characterized in that: A mounting hole is provided at the front end of the surface of the cage (2), a rotating shaft (8) is rotatably connected inside the mounting hole, and a baffle (9) is fixed on the circumferential surface of the rotating shaft (8).
5. The device for collecting bile online for beagle dogs according to claim 1, characterized in that: A sliding opening is provided on the circumferential surface of the fixing ring (12), a U-shaped plate (10) is slidably connected inside the sliding opening, the U-shaped plate (10) is clamped on the upper side of the baffle (9), a spring (11) is fixed on the upper side of the U-shaped plate (10), and the spring (11) is fixed on the upper side of the sliding opening.
6. The device for collecting bile online for beagle dogs according to claim 1, characterized in that: A storage box (6) is fixed to the upper end of the chassis (1), and two corresponding storage slots (7) are provided on the upper side of the storage box (6).