Multi-temperature-zone drug titration experimental device

Abstract

The utility model discloses a multi-temperature-zone drug titration experimental device which comprises a mounting disc and a storage assembly, a first mounting plate is fixed to the front end of the circumferential surface of the mounting disc, a displayer and a PLC are mounted on the front side of the first mounting plate, a rotating assembly is mounted at the upper end of the mounting disc, and a heating assembly is mounted at the lower end of the mounting disc; the storage assembly comprises a storage barrel, a first outer gear ring, an inner gear ring, a second outer gear ring, a second mounting plate, a first motor and a gear, storage grooves which are uniformly distributed are formed in the edge of the mounting plate, the storage barrel is rotationally connected into the storage grooves, and the first outer gear ring is fixed to the circumferential surface of the storage barrel; the upper end of the mounting disc is rotationally connected with an inner gear ring, and the inner gear ring is meshed with all the first outer gear rings. According to the utility model, a plurality of medicine analysis titrations can be simultaneously carried out, and meanwhile, the titration temperature can be adjusted according to requirements during titration, so that the experiment accuracy is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of pharmacokinetic experiments, in particular to a multi-temperature zone drug titration experimental device. Background Art

[0002] Drug analysis is a discipline that uses chemical, physical, biological and microbiological methods and techniques to study chemical testing of drugs, drug stability, bioavailability, drug clinical monitoring and qualitative and quantitative analysis of active ingredients in Chinese herbal medicines. It includes chemical testing of finished drugs, quality control of drug production processes, quality inspection of drug storage processes, clinical drug analysis, in vivo drug analysis, etc.

[0003] In order to improve the efficiency of titration experiments, a drug analysis titrator is used in the prior art for titration experiments. However, the existing drug analysis titrator has low efficiency when processing multiple drug analysis titrations, and the temperature during titration cannot be selected according to the needs during the titration experiment. Therefore, a multi-temperature zone drug titration experiment device is proposed. Utility Model Content

[0004] The technical problem to be solved by the utility model is to overcome the existing defects and provide a multi-temperature zone drug titration experimental device, which can simultaneously perform multiple drug analysis titrations and can adjust the titration temperature according to needs during titration to improve the accuracy of the experiment, thereby effectively solving the problems in the background technology.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a multi-temperature zone drug titration experimental device, comprising a mounting plate and a storage component;

[0006] A mounting plate 1 is fixed to the front end of the circumferential surface of the mounting plate, a display and a PLC controller are installed on the front side of the mounting plate 1, a rotating component is installed on the upper end of the mounting plate, and a heating component is installed on the lower end of the mounting plate;

[0007] The storage assembly includes a storage barrel, a first outer gear ring, an inner gear ring, a second outer gear ring, a second mounting plate, a first motor and a gear. The edge of the mounting plate is provided with evenly distributed storage grooves. The storage barrel is rotatably connected to the storage groove. The first outer gear ring is fixed on the circumferential surface of the storage barrel. The upper end of the mounting plate is rotatably connected to the inner gear ring. The inner gear ring is meshed with all the first outer gear rings. The second outer gear ring is fixed on the circumferential surface of the inner gear ring. The second mounting plate is fixed to the right end of the circumferential surface of the mounting plate. The first motor is installed on the upper side of the mounting plate. A gear is fixed on the output shaft of the first motor. The gear is meshed with the second outer gear ring. A fastening assembly is installed on the barrel wall of the storage barrel. The conical flasks required for the titration experiment are stored by arranging the storage assembly.

[0008] Wherein: the input end of the PLC controller is electrically connected to the output end of the external power supply, the output end of the PLC controller is electrically connected to the input end of the first motor, and the PLC controller is bidirectionally electrically connected to the display.

[0009] Furthermore, the rotating assembly includes a second motor, a rotating shaft, a connecting frame and a connecting ring. The second motor is installed at the lower end of the mounting plate. The rotating shaft is fixed on the output shaft of the second motor. The connecting frame is fixed on the upper end of the circumferential surface of the rotating shaft. The connecting ring is fixed on the front side of the connecting frame. The connecting ring corresponds to the storage barrel on the front side. The input end of the second motor is electrically connected to the output end of the PLC controller. The rotating assembly is provided to drive the burette required for the titration experiment to rotate.

[0010] Furthermore, it also includes a fixing component, which includes a threaded rod, a rubber disc and a turntable. A threaded hole is opened on the front side of the connecting frame. The internal thread of the threaded hole is connected to a threaded rod. The front end of the threaded rod is fixed with a rubber disc, and the rubber disc is located inside the connecting ring. The rear end of the threaded rod is fixed with a turntable. The burette required for the titration experiment is fixed by setting the fixing component.

[0011] Furthermore, the heating component includes an electric heating ring and a temperature sensor. The lower end of the mounting plate is provided with evenly distributed mounting grooves, and the mounting grooves correspond to the storage barrel. The electric heating ring is installed inside the mounting grooves. The temperature sensor is installed inside the storage slot opened at the upper end of the mounting plate. The storage barrel has an opening in the middle, and the temperature sensor is located inside the opening. The input end of the electric heating ring is electrically connected to the output end of the PLC controller, and the temperature sensor is bidirectionally electrically connected to the external PLC controller. The interior of the storage barrel is heated by setting the heating component.

[0012] Furthermore, the fastening assembly includes a sliding rod, a connecting disk, a spring and an arc-shaped fastening plate. The circumferential surface of the storage barrel is provided with evenly distributed sliding holes, the sliding holes are slidably connected to the sliding rod, the end surface of the sliding rod located inside the storage barrel is fixed with an arc-shaped fastening plate, the end surface of the sliding rod located outside the storage barrel is fixed with a connecting disk, the circumferential surface of the sliding rod is sleeved with a spring, one end of the spring is fixed on the circumferential surface of the storage barrel, and the other end of the spring is fixed on the end surface of the connecting disk. The conical flask required for the titration experiment is fixed by setting the fastening assembly.

[0013] Furthermore, an anti-skid pad is fixed inside the connecting ring, and evenly distributed anti-skid strips are fixed on the side of the anti-skid pad. The stability of the burette can be ensured by providing the anti-skid pad.

[0014] Compared with the prior art, the beneficial effects of the utility model are:

[0015] 1. The conical flasks used in the experiment are stored by setting a storage barrel. After storage, the fastening assembly inside the storage barrel will fix the conical flask. After fixation, the connecting ring is connected to the burette used in the experiment. After connection, the second motor is started to rotate the shaft to adjust the position of the burette. During the adjustment process, the burette will titrate the drug solution in the conical flasks inside all the storage barrels respectively. In this case, multiple drug analysis titrations can be completed, which greatly improves the efficiency of the experiment;

[0016] 2. The first motor can be started after titration to drive the gear to rotate. The gear rotates to rotate the second outer gear ring and the inner gear ring. The inner gear ring rotates to drive all the storage barrels to rotate. In this case, the titrated liquid medicine and the liquid medicine in the conical bottle inside the storage barrel can be fully mixed. After mixing, the reaction can be observed to complete the experiment, which is very convenient.

[0017] 3. By setting up the heating component, the required temperature values ​​of each storage barrel can be input into the PLC controller according to the needs before the titration experiment, and then all the electric heating rings are started to heat the inside of all the storage barrels. During the heating process, the temperature sensor located inside the storage barrel will detect the temperature inside each storage barrel. When the detected temperature value is the same as the value stored in the PLC controller, the PLC controller will automatically turn off all the electric heating rings. In this case, the experimental effects at different temperatures can be observed during the titration experiment, which greatly improves the accuracy of the experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the front structure of the utility model;

[0019] Figure 2 It is a left side sectional view of the utility model;

[0020] Figure 3 This is an enlarged view of point A of the utility model;

[0021] Figure 4 This is a schematic diagram of the structure of the fixing component of the utility model.

[0022] In the figure: 1 mounting plate, 2 mounting plate 1, 3 display, 4 PLC controller, 5 storage assembly, 51 storage barrel, 52 first outer gear ring, 53 inner gear ring, 54 second outer gear ring, 55 mounting plate 2, 56 first motor, 57 gear, 6 rotating assembly, 61 second motor, 62 rotating shaft, 63 connecting frame, 64 connecting ring, 7 fixing assembly, 71 threaded rod, 72 rubber disc, 73 turntable, 8 heating assembly, 81 electric heating ring, 82 temperature sensor, 9 fastening assembly, 91 sliding rod, 92 connecting plate, 93 spring, 94 arc-shaped fastening plate, 10 anti-slip pad. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0024] See also Figure 1-4 , this embodiment provides a multi-temperature zone drug titration experimental device, including a mounting plate 1 and a storage component 5;

[0025] Among them, a mounting plate 2 is fixed to the front end of the circumferential surface of the mounting plate 1, a display 3 and a PLC controller 4 are installed on the front side of the mounting plate 2, a rotating component 6 is installed on the upper end of the mounting plate 1 to drive the burette required for the titration experiment to rotate, and a heating component 8 is installed on the lower end of the mounting plate 1;

[0026] The rotating assembly 6 includes a second motor 61, a rotating shaft 62, a connecting frame 63 and a connecting ring 64. The second motor 61 is installed at the lower end of the mounting plate 1. The rotating shaft 62 is fixed on the output shaft of the second motor 61. The connecting frame 63 is fixed on the upper end of the circumferential surface of the rotating shaft 62. The connecting ring 64 is fixed on the front side of the connecting frame 63. The connecting ring 64 corresponds to the storage barrel 51 on the front side. The input end of the second motor 61 is electrically connected to the output end of the PLC controller 4.

[0027] The fixing assembly 7 is also included to fix the burette required for the titration experiment. The fixing assembly 7 includes a threaded rod 71, a rubber disc 72 and a rotating disk 73. A threaded hole is provided on the front side of the connecting frame 63. The threaded rod 71 is threadedly connected to the inner part of the threaded hole. The front end of the threaded rod 71 is fixed with a rubber disc 72. The rubber disc 72 is located inside the connecting ring 64. The rotating disk 73 is fixed to the rear end of the threaded rod 71.

[0028] The heating assembly 8 includes an electric heating ring 81 and a temperature sensor 82. The lower end of the mounting plate 1 is provided with evenly distributed mounting grooves, which correspond to the storage barrel 51. The electric heating ring 81 is installed inside the mounting groove. The storage barrel 51 is provided with a temperature sensor 82 inside the storage groove. The storage barrel 51 has an opening in the middle, and the temperature sensor 82 is located inside the opening. The input end of the electric heating ring 81 is electrically connected to the output end of the PLC controller 4. The temperature sensor 82 is bidirectionally electrically connected to the external PLC controller 4. The interior of the storage barrel 51 is heated by setting the heating assembly 8.

[0029] The storage assembly 5 includes a storage barrel 51, a first outer gear ring 52, an inner gear ring 53, a second outer gear ring 54, a second mounting plate 55, a first motor 56 and a gear 57. The edge of the mounting plate 1 is provided with evenly distributed storage grooves, the storage barrel 51 is rotatably connected inside the storage groove, the first outer gear ring 52 is fixed on the circumferential surface of the storage barrel 51, the inner gear ring 53 is rotatably connected to the upper end of the mounting plate 1, the inner gear ring 53 is meshed with all the first outer gear rings 52, the second outer gear ring 54 is fixed on the circumferential surface of the inner gear ring 53, the second mounting plate 55 is fixed to the right end of the circumferential surface of the mounting plate 1, the first motor 56 is installed on the upper side of the second mounting plate 55, the output shaft of the first motor 56 is fixed with a gear 57, the gear 57 is meshed with the second outer gear ring 54, A fastening assembly 9 is installed on the barrel wall of the storage barrel 51. The fastening assembly 9 includes a slide rod 91, a connecting disk 92, a spring 93 and an arc-shaped fastening plate 94. The circumferential surface of the storage barrel 51 is provided with evenly distributed sliding holes, and the slide rod 91 is slidably connected inside the sliding hole. The end surface of the slide rod 91 located inside the storage barrel 51 is fixed with an arc-shaped fastening plate 94. The end surface of the slide rod 91 located outside the storage barrel 51 is fixed with a connecting disk 92. A spring 93 is sleeved on the circumferential surface of the slide rod 91. One end of the spring 93 is fixed on the circumferential surface of the storage barrel 51, and the other end of the spring 93 is fixed on the end surface of the connecting disk 92. The conical flask required for the titration experiment is fixed by setting the fastening assembly 9, and the conical flask required for the titration experiment is stored by setting the storage assembly 5.

[0030] Among them: the input end of the PLC controller 4 is electrically connected to the output end of the external power supply, the output end of the PLC controller 4 is electrically connected to the input end of the first motor 56, and the PLC controller 4 is bidirectionally electrically connected to the display 3.

[0031] The anti-skid pad 10 is fixed inside the connecting ring 64 , and evenly distributed anti-skid strips are fixed on the side of the anti-skid pad 10 . The stability of the burette can be ensured by providing the anti-skid pad 10 .

[0032] The working principle of the utility model is as follows:

[0033] First, the required temperature values ​​in each storage barrel 51 can be input into the PLC controller 4 according to the needs, and then the conical flasks used in the experiment are placed into the interior of each storage barrel 51 one by one. After placement, the arc-shaped fastening plate 94 located inside the storage barrel 51 will fix the storage barrel 51 under the action of the spring 93 adjacent to it. After fixing, all the electric heating rings 81 are started to heat the interior of all the storage barrels 51. During the heating process, the temperature sensor 82 located inside the storage barrel 51 will detect the temperature inside each storage barrel 51. When the detected temperature value is the same as the value stored in the PLC controller 4, the PLC controller 4 will automatically turn off all the electric heating rings 81, and then insert the burette into the interior of the connecting ring 64. After insertion, rotate the threaded rod 71 to move the rubber disk 72 forward to fix the burette. After fixing, start the second motor 61 to rotate the shaft 62 to adjust the position of the burette. During the adjustment process, the burette will titrate the drug solution in the conical flasks inside all the storage barrels 51. In this case, multiple drug analysis titrations can be completed;

[0034] After titration, the first motor 56 is started to drive the gear 57 to rotate. The gear 57 rotates, which causes the second outer gear ring 54 and the inner gear ring 53 to rotate. The inner gear ring 53 rotates, which causes all the first outer gear rings 52 to rotate. The rotation of all the first outer gear rings 52 drives all the storage barrels 51 to rotate. In this case, the titrated liquid medicine and the liquid medicine in the conical flask inside the storage barrel 51 can be fully mixed. After mixing, the experiment can be completed by observing the reaction, which is very convenient.

[0035] It is worth noting that the PLC controller 4 disclosed in the above embodiment is specifically a Siemens S7-200 model, the display 3 can select an SC170-NGCM embedded display, the first motor 56 and the second motor 61 can select a 1LE0003 three-phase asynchronous motor, the electric heating ring 81 can select a BK nickel-chromium heating wire, and the temperature sensor 82 can select a LSCI-TZ03 laser focusing infrared temperature sensor. The control switch group controls the operation of the first motor 56, the second motor 61 and the electric heating ring 81 using methods commonly used in the prior art.

[0036] The above description is only an embodiment of the present invention, and does not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made by using the contents of the specification and drawings of the present invention, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. A multi-temperature zone drug titration experimental device, characterized in that: It comprises a mounting plate (1) and a storage assembly (5); A mounting plate (2) is fixed to the front end of the circumferential surface of the mounting plate (1); a display (3) and a PLC controller (4) are mounted on the front side of the mounting plate (2); a rotating assembly (6) is mounted on the upper end of the mounting plate (1); and a heating assembly (8) is mounted on the lower end of the mounting plate (1); The storage assembly (5) comprises a storage barrel (51), a first outer toothed ring (52), an inner toothed ring (53), a second outer toothed ring (54), a second mounting plate (55), a first motor (56) and a gear (57). The edge of the mounting plate (1) is provided with evenly distributed storage grooves, the interior of the storage grooves is rotatably connected to the storage barrel (51), the first outer toothed ring (52) is fixed on the circumferential surface of the storage barrel (51), the upper end of the mounting plate (1) is rotatably connected to the inner toothed ring (53), the inner toothed ring (54) is fixed to the circumferential surface of the storage barrel (51), the upper end of the mounting plate (1) is rotatably connected to the inner toothed ring (53), and the inner toothed ring (54) is fixed to the circumferential surface of the storage barrel (51). The ring (53) is meshed with all the first outer toothed rings (52); a second outer toothed ring (54) is fixed on the circumferential surface of the inner toothed ring (53); a second mounting plate (55) is fixed on the right end of the circumferential surface of the mounting plate (1); a first motor (56) is mounted on the upper side of the second mounting plate (55); a gear (57) is fixed on the output shaft of the first motor (56); the gear (57) is meshed with the second outer toothed ring (54); a fastening assembly (9) is mounted on the barrel wall of the storage barrel (51); Wherein: the input end of the PLC controller (4) is electrically connected to the output end of an external power supply, the output end of the PLC controller (4) is electrically connected to the input end of a first motor (56), and the PLC controller (4) is bidirectionally electrically connected to a display (3).

2. A multi-temperature zone drug titration experimental device according to claim 1, characterized in that: The rotating assembly (6) comprises a second motor (61), a rotating shaft (62), a connecting frame (63) and a connecting ring (64); the second motor (61) is installed at the lower end of the mounting plate (1); the rotating shaft (62) is fixed on the output shaft of the second motor (61); the connecting frame (63) is fixed on the upper end of the circumferential surface of the rotating shaft (62); the connecting ring (64) is fixed on the front side of the connecting frame (63); the connecting ring (64) corresponds to the storage barrel (51) on the front side; the input end of the second motor (61) is electrically connected to the output end of the PLC controller (4).

3. A multi-temperature zone drug titration experimental device according to claim 2, characterized in that: The invention also comprises a fixing assembly (7), wherein the fixing assembly (7) comprises a threaded rod (71), a rubber disc (72) and a rotating disc (73); a threaded hole is provided on the front side of the connecting frame (63); the threaded rod (71) is threadedly connected to the inside of the threaded hole; the front end of the threaded rod (71) is fixed with a rubber disc (72); the rubber disc (72) is located inside the connecting ring (64); and the rotating disc (73) is fixed to the rear end of the threaded rod (71).

4. The multi-temperature zone drug titration experimental device according to claim 1, characterized in that: The heating component (8) comprises an electric heating ring (81) and a temperature sensor (82); the lower end of the mounting plate (1) is provided with evenly distributed mounting grooves, the mounting grooves corresponding to the storage barrel (51); the electric heating ring (81) is installed inside the mounting grooves; the storage slot opened at the upper end of the mounting plate (1) is installed inside the storage slot; an opening is provided at the middle of the storage barrel (51); the temperature sensor (82) is located inside the opening; the input end of the electric heating ring (81) is electrically connected to the output end of the PLC controller (4); and the temperature sensor (82) is bidirectionally electrically connected to the external PLC controller (4).

5. The multi-temperature zone drug titration experimental device according to claim 1, characterized in that: The fastening assembly (9) comprises a slide rod (91), a connecting disk (92), a spring (93) and an arc-shaped fastening plate (94). The circumferential surface of the storage barrel (51) is provided with evenly distributed sliding holes, the interior of the sliding holes is slidably connected with the slide rod (91), the end surface of the slide rod (91) located inside the storage barrel (51) is fixed with an arc-shaped fastening plate (94), the end surface of the slide rod (91) located outside the storage barrel (51) is fixed with the connecting disk (92), the circumferential surface of the slide rod (91) is sleeved with a spring (93), one end of the spring (93) is fixed on the circumferential surface of the storage barrel (51), and the other end of the spring (93) is fixed on the end surface of the connecting disk (92).

6. A multi-temperature zone drug titration experimental device according to claim 2, characterized in that: An anti-skid pad (10) is fixed inside the connecting ring (64), and evenly distributed anti-skid strips are fixed on the side of the anti-skid pad (10).

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