Sample analyzer

Abstract

The utility model relates to the technical field of testing, and particularly discloses a sample analyzer which is characterized in that a first dispatching station is arranged on a dispatching disc; an incubation scheduling position is arranged on the incubation disc, and the incubation disc and the scheduling disc are coaxially arranged and relatively independently rotate; the magnetic separation assembly is arranged on the periphery of the dispatching disc and is provided with a separation station; the output end of the transfer assembly can swing around the rotating shaft, the axis of the rotating shaft is parallel to the axis of the incubation disc, and the first dispatching station, the incubation dispatching station and the separation station are all located on the swing path of the output end of the transfer assembly. According to the arrangement, the occupied area is reduced, and miniaturization and compactness development of equipment is facilitated.

Description

Technical Field

[0001] The utility model relates to the technical field of testing, in particular to a sample analyzer. Background Art

[0002] The sample analyzer based on chemiluminescent immunoassay has become a mature medical diagnostic equipment with the advantages of high sensitivity, low nonspecific adsorption and high accuracy. In order to improve the single test throughput of the sample analyzer, to meet the needs of a large number of clinical sample tests, and to improve the work efficiency of users such as doctors who need to make diagnoses based on sample measurement results. The prior art sets the incubation tray and the scheduling tray separately, so that when multiple test items are carried out, the previous test items can enter the incubation stage, and the subsequent test items can start scheduling; after the mixed liquid in the reaction cup is incubated, the magnetic separation component is needed to clean the reactants before detection, so it is necessary to set a gripper between the incubation tray and the magnetic separation component; in many cases, after the cleaning is completed, the reagent needs to be refilled for the second time, so it is also necessary to set a gripper between the magnetic separation component and the scheduling tray to move the reaction cup to the scheduling tray. On the one hand, the existing incubation tray and the scheduling tray are set in different positions, resulting in a large footprint of the entire sample analyzer, which is not conducive to the miniaturization and compact development of the equipment; on the other hand, the number of grippers is large, resulting in high equipment cost and large footprint. Utility Model Content

[0003] The utility model aims to provide a sample analyzer to solve the problems of large floor space and high cost in the prior art.

[0004] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0005] A sample analyzer, comprising:

[0006] A scheduling disk, wherein a first scheduling station is provided on the scheduling disk;

[0007] An incubation tray, wherein an incubation scheduling position is provided on the incubation tray, and the incubation tray and the scheduling tray are coaxially arranged and rotate relatively independently;

[0008] A magnetic separation component, the magnetic separation component is arranged on the outer periphery of the scheduling disk, and the magnetic separation component has a separation station;

[0009] A transfer component, wherein the output end of the transfer component can swing around a rotating shaft, the axis of the rotating shaft is parallel to the axis of the incubation plate, and the first scheduling station, the incubation scheduling station and the separation station are all located on the swinging path of the output end of the transfer component.

[0010] As an optional technical solution of a sample analyzer, the scheduling disk is ring-shaped, the incubation disk is disc-shaped, and the incubation disk is located inside the scheduling disk.

[0011] As an optional technical solution of a sample analyzer, a reading component of the sample analyzer has a pre-test station at one end and a test station at the other end, and the pre-test station is located on the swing path of the output end of the transfer component.

[0012] As an optional technical solution of a sample analyzer, the pre-test station is located between the first scheduling station and the separation station.

[0013] As an optional technical solution of a sample analyzer, the sample analyzer includes a waste cup member, which is arranged on the swing path of the output end of the transfer component and is used to receive a reaction cup that has completed detection.

[0014] As an optional technical solution of a sample analyzer, the waste cup part is located between the first scheduling station and the pre-test station.

[0015] As an optional technical solution of a sample analyzer, the sample analyzer includes a reagent tray, the reagent tray is used to hold reagents used for the reaction, the reagent tray is arranged on the periphery of the scheduling tray, and the reading component is located between the reagent tray and the magnetic separation component.

[0016] As an optional technical solution of a sample analyzer, the reagent disk is located at the front of a rack of the sample analyzer; and / or,

[0017] The scheduling disk is arranged at the rear side of the reagent disk; and / or,

[0018] The magnetic separation component is arranged on the rear side of the reagent disk.

[0019] As an optional technical solution of a sample analyzer, the swing angle of the output end of the transfer component is less than or equal to 180 degrees; and / or,

[0020] The transfer assembly includes a swing arm, a lifting arm and a gripper, one end of the swing arm is rotatably disposed on the rotating shaft, the lifting arm is slidably disposed at the other end of the swing arm along a vertical direction, and the gripper is disposed at the lower end of the lifting arm, and the gripper is used to grab the reaction cup.

[0021] As an optional technical solution for a sample analyzer, the incubation tray has a plurality of incubation positions, and the plurality of incubation positions form at least two working rings. There are at least two incubation scheduling positions, and the incubation positions are used to place reaction cups. During the rotation of the incubation tray, the incubation positions in each working ring can pass through the corresponding incubation scheduling position.

[0022] The beneficial effects of the utility model are:

[0023] The utility model provides a sample analyzer, which reduces the footprint of the scheduling disk and the incubation disk by coaxially arranging the scheduling disk and the incubation disk, resulting in a smaller footprint of the entire sample analyzer, which is conducive to the miniaturization and compactness of the equipment. In addition, the magnetic separation component is arranged on the periphery of the scheduling disk, and in the process of the output end of the transfer component swinging around the rotating shaft, it can pass through the first scheduling station, the incubation scheduling station and the separation station, so that the reaction cup is transferred from the incubation disk to the magnetic separation component, and the reaction cup is transferred from the magnetic separation component to the scheduling disk. The operation can be completed by only one transfer component, which is conducive to reducing equipment costs and reducing the footprint. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 This is a schematic diagram of the structure of a sample analyzer in an embodiment of the utility model;

[0025] Figure 2 Schematic diagram of various working stations of the sample analyzer in the embodiment of the utility model.

[0026] In the figure:

[0027] 1000, rack;

[0028] 100, dispatching plate; 110, first dispatching station; 120, second dispatching station; 130, third dispatching station; 140, fourth dispatching station;

[0029] 200, incubation tray; 210, incubation scheduling position;

[0030] 300, magnetic separation assembly; 310, separation station;

[0031] 400, transfer assembly; 410, swing path; 420, mechanical swing arm; 421, cup dispensing member;

[0032] 500, reading component; 510, pre-test station; 520, test station;

[0033] 600, waste cup part; 610, waste liquid suction part; 620, waste liquid position;

[0034] 700, reagent disk; 710, reagent needle; 711, reagent path;

[0035] 810, first track; 811, first loading position; 820, second track; 821, second loading position; 830, recovery track; 840, sample needle; 841, sample path. DETAILED DESCRIPTION

[0036] The technical solution of the utility model will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0037] In the description of the present utility model, it should be noted that the orientation or positional relationship indicated by the terms "center", "up", "down", "left", "right", "vertical", "horizontal", "inside", "outside", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present utility model. In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance. Among them, the terms "first position" and "second position" are two different positions, and the first feature "above", "above" and "above" the second feature include the first feature being directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. The first feature "below", "below" and "below" the second feature include the first feature being directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.

[0038] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0039] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention.

[0040] like Figure 1 and Figure 2As shown, this embodiment provides a sample analyzer, which includes a scheduling disk 100, an incubation disk 200, a magnetic separation component 300 and a transfer component 400, wherein a first scheduling station 110 is arranged on the scheduling disk 100; an incubation scheduling position 210 is arranged on the incubation disk 200, and the incubation disk 200 is coaxially arranged with the scheduling disk 100 and rotates relatively independently; the magnetic separation component 300 is arranged on the outer periphery of the scheduling disk 100, and the magnetic separation component 300 has a separation station 310; the output end of the transfer component 400 can swing around a rotating shaft, and the axis of the rotating shaft is parallel to the axis of the incubation disk 200, and the first scheduling station 110, the incubation scheduling position 210 and the separation station 310 are all located on the swing path 410 of the output end of the transfer component 400.

[0041] The sample analyzer reduces the footprint of the scheduling disk 100 and the incubation disk 200 by coaxially arranging the scheduling disk 100 and the incubation disk 200, resulting in a smaller footprint of the entire sample analyzer, which is conducive to the miniaturization and compactness of the device. In addition, the magnetic separation component 300 is arranged on the periphery of the scheduling disk 100, and in the process of the output end of the transfer component 400 swinging around the rotation axis, it can pass through the first scheduling station 110, the incubation scheduling station 210 and the separation station 310, so that the reaction cup is transferred from the incubation disk 200 to the magnetic separation component 300, and the reaction cup is transferred from the magnetic separation component 300 to the scheduling disk 100. The operation can be completed by only one transfer component 400, reducing the number of transfer components 400, which is conducive to reducing the cost of the sample analyzer and reducing the footprint.

[0042] In some embodiments, the scheduling disk 100 is annular, the incubation disk 200 is disc-shaped, and the incubation disk 200 is located inside the scheduling disk 100. The above arrangement makes the incubation disk 200 surrounded by the scheduling disk 100, and the incubation disk 200 is located in the center, which helps to reduce the heat dissipation in the incubation disk 200, is conducive to the accumulation of heat, and under the premise of constant temperature, the amount of heat required to be provided is reduced, thereby achieving energy conservation and emission reduction. Further, a thermal insulation layer can be set around the outer periphery of the incubation disk 200, and the thermal insulation layer is located between the incubation disk 200 and the scheduling disk 100. Specifically, the thermal insulation layer can be a vacuum layer or a foam layer.

[0043] In this embodiment, the magnetic separation component 300 is located at the periphery of the scheduling disk 100, and the first scheduling station 110 is located between the incubation scheduling station 210 and the separation station 310. With the above position arrangement, after the incubation is completed, the reaction cup is transferred from the incubation scheduling station 210 to the separation station 310 by the transfer component 400, the reactants of the sample and the reagent in the reaction cup are cleaned, and then the test is performed, and after the test is completed, the reaction cup is transferred to the first scheduling station 110, and then the reaction cup is transferred to the next station under the rotation of the scheduling disk 100.

[0044] Regarding the test process, it is to collect and analyze the optical signal data of the reactants. In this embodiment, the reading component 500 of the sample analyzer has a pre-test station 510 at one end and a test station 520 at the other end, and the pre-test station 510 is located on the swing path 410 of the output end of the transfer component 400. The above-mentioned setting enables the reaction cup to be transferred between the first scheduling station 110, the incubation scheduling station 210, the separation station 310 and the pre-test station 510 under the drive of the transfer component 400, thereby greatly reducing the number of transfer components 400, reducing costs, and reducing the floor space; at the same time, the setting of the same transfer component 400 makes the scheduling disk 100, the magnetic separation component 300, and the pre-test station 510 of the reading component 500 surround the outer periphery of the axis of the rotating shaft of the transfer component 400, which is compact in structure and further reduces the floor space. It should be noted that the transfer of the reaction cup between the pre-test station 510 and the test station 520 and the method of testing the reactants at the test station 520 by the reading component 500 are well known to those skilled in the art and will not be described in detail here.

[0045] The pre-test station 510 is located between the first scheduling station 110 and the separation station 310. This arrangement allows the reactants in the reaction cup to be transferred to the pre-test station 510 at the shortest distance after cleaning, thereby improving the detection efficiency; at the same time, the time between the reactants after cleaning and before detection is reduced, thereby reducing the impact on the test results and improving the test accuracy.

[0046] When the test is completed, the reaction cup needs to be discarded to achieve the subsequent recycling of the reaction cup. Specifically, in this embodiment, the sample analyzer includes a waste cup member 600, which is arranged on the swing path 410 at the output end of the transfer component 400 and is used to receive the reaction cup that has completed the test. In other words, after the reactant in the reaction cup is tested, the reaction cup is thrown into the waste cup member 600.

[0047] Regarding the position of the waste cup member 600, in some embodiments, the waste cup member 600 is located between the first scheduling station 110 and the pre-test station 510. This position layout allows the reaction cup to be transferred from the test station 520 to the pre-test station 510 by the reading component 500 after the test is completed, and then the reaction cup is transferred to the waste cup member 600 by the transfer component 400.

[0048] Furthermore, in order to avoid residual reactants in the reaction cup collected by the waste cup part 600, in some embodiments, the sample analyzer is also provided with a waste liquid suction part 610 and a waste liquid barrel. The waste liquid barrel is located at the waste liquid position 620, and the waste liquid position 620 is located outside the scheduling disk 100. The scheduling disk 100 is provided with a second scheduling station 120. The output end of the waste liquid suction part 610 can move between the second scheduling station 120 and the waste liquid barrel, and can absorb the reactants in the reaction cup on the second scheduling station 120 and discharge them into the waste liquid barrel. This position layout allows, after the test is completed, the reaction cup is first transferred from the test station 520 to the pre-test station 510 by the reading component 500, and then the reaction cup is moved to the first scheduling station 110 by the transfer component 400. The scheduling disk 100 rotates to move the reaction cup to the second scheduling station 120, and the reactants in the reaction cup are sucked by the waste liquid suction piece 610 and discharged into the waste liquid barrel of the waste liquid position 620. The scheduling disk 100 rotates again to move the reaction cup to the first scheduling station 110, and finally the reaction cup is transferred to the waste cup piece 600 by the transfer component 400.

[0049] To improve the test efficiency, in some embodiments, the incubation tray 200 has a plurality of incubation positions, which enclose at least two working rings, and there are at least two incubation scheduling positions 210, which are used to place reaction cups. During the rotation of the incubation tray 200, the incubation positions in each working ring can pass through the corresponding incubation scheduling position 210. The setting of the plurality of incubation positions allows the incubation tray 200 to hold a plurality of reaction cups at the same time, so as to complete the incubation at the same time, thereby improving the test efficiency.

[0050] The incubation positions are surrounded by three working rings, and there are three incubation scheduling positions 210. It is worth noting that the three incubation scheduling positions 210 are all located on the swing path 410 of the transfer assembly 400, and each time the scheduling disk 100 rotates, three incubation positions move to the three incubation scheduling positions 210 accordingly.

[0051] The swing angle of the output end of the transfer assembly 400 is less than or equal to 180 degrees. The above angle limit, to a certain extent, limits the positional relationship between the magnetic separation assembly 300 and the scheduling disk 100, making the two as compact as possible and reducing the footprint of the sample analyzer.

[0052] Regarding the structure of the transfer assembly 400, in this embodiment, the transfer assembly 400 includes a swing arm, a lifting arm and a gripper. One end of the swing arm is rotatably disposed on a rotating shaft, the lifting arm is slidably disposed at the other end of the swing arm along a vertical direction, and the gripper is disposed at the lower end of the lifting arm, and the gripper is used to grab the reaction cup.

[0053] After incubation, after the reactant is cleaned, there may be a situation of secondary incubation. In the present embodiment, the sample analyzer includes a reagent tray 700, which is used to hold the reagent used for the reaction, and the reagent tray 700 is arranged at the periphery of the scheduling tray 100, and the reading component 500 is located between the reagent tray 700 and the magnetic separation component 300. The above-mentioned setting makes it possible to refill the reagent after the reactant in the reaction cup is cleaned, and to incubate the processes again to meet different process requirements. At the same time, by means of the position setting of the above-mentioned reagent tray 700, the structure of the reading component 500, the reagent tray 700 and the magnetic separation component 300 is compact, reducing the floor space; finally, the above-mentioned positional relationship makes the distance between the reagent tray 700 and the scheduling tray 100 as close as possible, shortening the time of filling the reagent and improving the efficiency of filling the reagent.

[0054] For ease of operation, in some embodiments, the reagent tray 700 is located at the front of the rack 1000 of the sample analyzer. Wherein, the scheduling disk 100 is located at the rear side of the reagent tray 700. The magnetic separation assembly 300 is located at the rear side of the reagent tray 700. The above position is limited so that the operator can place the reagent in the reagent tray 700 as quickly as possible, which improves the convenience and efficiency of operation. The reagent needle 710 can swing around its own axis so that the output end of the reagent needle 710 can move around the reagent path 711, and the reagent path 711 and the reagent tray 700 intersect at the reagent position, and the reagent container for holding the reagent is placed at the reagent position. The reagent needle 710 transfers the reagent at the reagent position in the reagent tray 700 to the reaction cup of the third scheduling station 130. The output end of the reagent needle 710 is provided with a suction piece for sucking the reagent in the reagent container and discharging it into the reaction cup.

[0055] It is worth noting that the rack 1000 also has a rear portion opposite to the front portion, and a conveying track is provided at the rear portion of the rack 1000 for conveying samples, and the operator operates at the front portion of the rack 1000 to complete operations such as reagent replenishment. The above arrangement can keep samples with infectious aerosols away from the front portion of the rack 1000 and the operator as far as possible, thereby improving the safety of the operator.

[0056] The sample needle 840 can swing around its own axis so that the output end of the sample needle 840 moves in the sample path 841. The transmission track includes a first track 810 and a second track 820. The first track 810 and the second track 820 intersect with the sample path 841 to form a first loading position 811 and a second loading position 821. The output end of the sample needle 840 is provided with a suction piece for sucking the reagent in the sample container and discharging it into the reaction cup.

[0057] In some embodiments, the transmission speed of the first track 810 is greater than the transmission speed of the second track 820, and the first track 810 is closer to the sample needle 840, and the first track 810 is used to transmit the expedited sample. The sample needle 840 is used to extract the samples from the first loading position 811 and the second loading position 821 and fill them into the reaction cup at the fourth scheduling position 140 on the scheduling plate 100.

[0058] The sample is placed in a sample container, and the sample analyzer is further provided with a recovery track 830, and the sample container from which the sample is extracted is moved by the manipulator to the recovery track 830. In some embodiments, the recovery track 830 is connected to the first track 810 and to the second track 820, and after the sample in the sample container is extracted, the sample container is pushed by the pushing mechanism and moved to the recovery track 830.

[0059] It is worth mentioning that the scheduling tray 100 , incubation tray 200 , magnetic separation assembly 300 , transfer assembly 400 , reading assembly 500 , waste cup 600 , reagent tray 700 and transmission track and other components are all arranged on the frame 1000 .

[0060] In some embodiments, the reaction cup is transferred from the cup dispensing member 421 to the scheduling plate 100 by the mechanical swing arm 420. The rotation process of the scheduling plate 100 enables the reaction cup to move to each scheduling station.

[0061] Obviously, the above embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the implementation methods of the present invention. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all implementation methods here. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of the present invention shall be included in the protection scope of the claims of the present invention.

Claims

1. A sample analyzer, characterized in that: include: A scheduling disk (100), wherein a first scheduling station (110) is provided on the scheduling disk (100); An incubation tray (200), wherein an incubation scheduling position (210) is provided on the incubation tray (200), and the incubation tray (200) and the scheduling tray (100) are coaxially arranged and rotate relatively independently; A magnetic separation component (300), the magnetic separation component (300) being arranged on the outer periphery of the scheduling disk (100), and the magnetic separation component (300) having a separation station (310); A transfer assembly (400), wherein the output end of the transfer assembly (400) can swing around a rotation axis, the axis of the rotation axis is parallel to the axis of the incubation plate (200), and the first scheduling station (110), the incubation scheduling station (210) and the separation station (310) are all located on a swing path (410) of the output end of the transfer assembly (400).

2. The sample analyzer according to claim 1, characterized in that: The scheduling tray (100) is ring-shaped, the incubation tray (200) is disc-shaped, and the incubation tray (200) is located inside the scheduling tray (100).

3. The sample analyzer according to claim 1, characterized in that: The reading component (500) of the sample analyzer has a pre-test station (510) at one end and a test station (520) at the other end. The pre-test station (510) is located on the swing path (410) of the output end of the transfer component (400).

4. The sample analyzer according to claim 3, characterized in that: The pre-test station (510) is located between the first scheduling station (110) and the separation station (310).

5. The sample analyzer according to claim 4, characterized in that: The sample analyzer comprises a waste cup member (600), which is arranged on a swing path (410) at the output end of the transfer component (400) and is used to receive a reaction cup that has completed detection.

6. The sample analyzer according to claim 5, characterized in that: The waste cup part (600) is located between the first scheduling station (110) and the pre-test station (510).

7. The sample analyzer according to claim 3, characterized in that: The sample analyzer comprises a reagent disk (700) for containing reagents used for the reaction. The reagent disk (700) is arranged on the periphery of the scheduling disk (100), and the reading component (500) is located between the reagent disk (700) and the magnetic separation component (300).

8. The sample analyzer according to claim 7, characterized in that: The reagent disk (700) is located at the front of the rack (1000) of the sample analyzer; and / or, The scheduling disk (100) is arranged at the rear side of the reagent disk (700); and / or, The magnetic separation component (300) is arranged on the rear side of the reagent disk (700).

9. The sample analyzer according to claim 1, characterized in that: The swing angle of the output end of the transfer assembly (400) is less than or equal to 180 degrees; and / or, The transfer assembly (400) comprises a swing arm, a lifting arm and a gripper, wherein one end of the swing arm is rotatably arranged on the rotating shaft, the lifting arm is slidably arranged on the other end of the swing arm along the vertical direction, and the gripper is arranged at the lower end of the lifting arm, and the gripper is used to grab the reaction cup.

10. The sample analyzer according to any one of claims 1 to 9, characterized in that: The incubation tray (200) has a plurality of incubation positions, and the plurality of incubation positions form at least two working rings. The incubation scheduling positions (210) have at least two, and the incubation positions are used to place reaction cups. During the rotation of the incubation tray (200), the incubation positions in each working ring can pass through the corresponding incubation scheduling position (210).

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