Polypeptide continuous desalting device

Abstract

The utility model discloses a continuous polypeptide desalting device which is characterized in that a supporting mechanism comprises two positioning blocks and a sliding rod, the two positioning blocks are fixed below a shell, the sliding rod is mounted on the positioning blocks in a sliding manner, one end of the sliding rod is fixedly connected with a bridging block, shaft plates are symmetrically mounted on the bridging block, one side of each shaft plate is rotationally connected with a shaft block, and the other side of each shaft block is rotationally connected with a rotating shaft; a rectangular block is fixed to the top of the shaft block, and a first supporting column and a second supporting column are installed on the two sides of the rectangular block, through use of the supporting mechanism, when the nanofiltration membrane is installed, the nanofiltration membrane is pushed into the shell, and the lower portion of the nanofiltration membrane is supported by an arc-shaped support; therefore, when the nanofiltration membrane is mounted, a worker does not need to manually hold the lower part of the nanofiltration membrane or the nanofiltration membrane needs to be mounted by multiple persons, and the mounting convenience of the nanofiltration membrane is improved.

Description

Technical Field

[0001] The utility model belongs to the technical field of polypeptide desalination, and in particular relates to a polypeptide continuous desalination device. Background Art

[0002] Peanut polypeptides are usually prepared by protein enzymatic hydrolysis. In order to ensure the activity of the protease and maintain the hydrolysis rate, some alkali or acid must be added to adjust the pH value of the system, so that the produced polypeptide products contain a certain amount of salt, which will affect the purity and application range of the product and have a negative impact on its functional activity. Therefore, it is necessary to desalt the polypeptide products.

[0003] At present, the nanofiltration membrane needs to be replaced or cleaned when used for a long time. When the nanofiltration membrane is disassembled and installed, the staff needs to manually drag the bottom of the nanofiltration membrane for installation, which is more laborious and inconvenient, and the additional support bracket device will increase the cost. Utility Model Content

[0004] The utility model aims to provide a polypeptide continuous desalination device to solve the installation and cost problems in the prior art.

[0005] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0006] A polypeptide continuous desalination device comprises a housing, a connecting pipe is installed at the rear of the housing, a liquid inlet is provided on one side of the connecting pipe, a nanofiltration membrane is detachably installed inside the housing, and a supporting mechanism is provided below the housing, the supporting mechanism is used for supporting the nanofiltration membrane during installation;

[0007] The supporting mechanism includes a positioning block and a sliding rod. Two positioning blocks are fixed at the bottom of the shell. The sliding rod is slidably installed on the positioning block. One end of the sliding rod is fixedly connected to a bridging block. An axis plate is symmetrically installed on the bridging block. One side of the axis plate is rotatably connected to an axis block. A rectangular block is fixed on the top of the axis block. A first supporting column and a second supporting column are installed on both sides of the rectangular block.

[0008] Furthermore, the tops of the first support column and the second support column are arc-shaped brackets. When the support mechanism is fully unfolded, the arc-shaped bracket and the housing remain concentric, which is more conducive to ensuring the concentricity with the housing when installing the nanofiltration membrane.

[0009] Furthermore, the thickness of the first support column is greater than the thickness of the second support column.

[0010] Furthermore, a central shaft is installed on the shaft block and the shaft plate, and a torsion spring is sleeved on the central shaft. Under the influence of the torsion spring, the shaft block will automatically flip upwards, that is, the first support column and the second support column will flip.

[0011] Further, a stopper is fixed on the top of the shaft plate. Under the influence of the stopper, the turning angle of the shaft block will be blocked by the stopper, so that the turning position of the shaft block remains vertical to the shaft plate, that is, °.

[0012] Furthermore, a link column is provided on the side of the shaft plate, and a first handle is provided below the link column. The first handle can directly pull out the support mechanism under force, and the structure can adapt to the stacking of multiple shells, and is suitable for continuous desalination of polypeptides.

[0013] Furthermore, a magnetic block is provided at one end of the slide bar near the bridge block, a U-shaped plate is installed above the bridge block, and a second handle is installed on the side of the U-shaped plate. When the support mechanism is fully retracted, the magnetic block will be adsorbed on the positioning block to prevent the support mechanism from being ejected due to the force generated by the torsion spring.

[0014] Furthermore, the supporting mechanism is made of lightweight plastic material, which can reduce the burden of the supporting mechanism on the outer shell, making the structure light, and the damaged plastic material can be easily replaced, so the overall cost will be reduced accordingly. The sliding rod is made of metal material with good hardness to prevent bending and deformation due to force.

[0015] The technical solution of the utility model has the following beneficial effects:

[0016] 1. Use of the support mechanism: When installing the nanofiltration membrane, push the nanofiltration membrane toward the inside of the housing, and the arc-shaped bracket drags the bottom of the nanofiltration membrane. In this way, when installing the nanofiltration membrane, there is no need for the staff to manually drag the bottom of the nanofiltration membrane or require multiple people to install it, thereby improving the convenience of nanofiltration membrane installation.

[0017] 2. The support mechanism has both retractable and expanded forms, which is easy to adjust. The plastic material can reduce the burden of the support mechanism on the shell, making the structure light. If the plastic material is damaged, it can be easily replaced and the overall cost will be reduced accordingly. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings required for describing the embodiments are briefly introduced below.

[0019] Figure 1 It is a schematic diagram of the overall structure of the utility model.

[0020] Figure 2 It is a schematic diagram of the split structure of the utility model.

[0021] Figure 3 For the utility model Figure 2 Enlarged view of point A in the middle.

[0022] Figure 4 It is a contraction diagram of the present utility model.

[0023] Figure 5 This is a structural schematic diagram of the second embodiment of the present utility model.

[0024] Figure numerals: 10, outer shell; 11, connecting pipe; 12, liquid inlet; 13, nanofiltration membrane; 14, positioning block; 15, sliding rod; 16, bridging block; 17, shaft plate; 18, shaft block; 19, rectangular block; 20, first support column; 21, second support column; 22, arc bracket; 23, connecting column; 24, first handle; 25, central axis; 26, magnetic block; 27, U-shaped plate; 28, second handle; 29, stop block. DETAILED DESCRIPTION

[0025] In order to make the purpose, technical solution and advantages of the utility model clearer, the utility model will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the utility model and are not used to limit the utility model. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0026] Embodiment 1:

[0027] refer to Figure 1 A polypeptide continuous desalination device comprises a housing 10, the housing 10 is stably installed by an external bracket, a connecting pipe 11 is installed at the rear of the housing 10, a liquid inlet 12 is provided on one side of the connecting pipe 11, a nanofiltration membrane 13 is detachably installed inside the housing 10, and a supporting mechanism is provided below the housing 10, the supporting mechanism is used to support the nanofiltration membrane 13 when it is installed;

[0028] In the above scheme, the polypeptide product is dissolved in water to form a solution, and the solution enters the nanofiltration membrane 13 from the liquid inlet 12. The nanofiltration membrane 13 is set to allow the solution to pass through the nanofiltration membrane 13 for desalination. Under the pressure difference, salt and small molecules pass through the nanofiltration membrane 13, while large molecules such as polypeptides will be retained, thereby achieving separation of polypeptides and salts to obtain a purer polypeptide product. The polypeptide solution to be filtered is continuously introduced from the liquid inlet 12 to continuously perform the desalination operation.

[0029] refer to Figure 1-Figure 4The support mechanism includes a positioning block 14 and a slide bar 15. The positioning block 14 is fixed at the bottom of the housing 10 and has two slide bars 15. The positioning block 14 is slidably mounted with the slide bar 15. One end of the slide bar 15 is fixedly connected with a bridge block 16. The bridge block 16 is symmetrically mounted with an axis plate 17. One side of the axis plate 17 is rotatably connected with an axis block 18. A rectangular block 19 is fixed on the top of the axis block 18. The first support column 20 and the second support column 21 are mounted on both sides of the rectangular block 19. The length of the rectangular block 19 is used to determine the installation spacing of the first support column 20 and the second support column 21. The top of the first support column 20 and the second support column 21 is an arc bracket 22. When the support mechanism is fully unfolded, the arc bracket 22 remains concentric with the housing 10. The concentricity can be more conducive to ensuring the concentricity with the housing 10 when installing the nanofiltration membrane 13.

[0030] In the above scheme, Figure 4 The shape in is the contracted shape of the support mechanism. Figure 1-Figure 2 The shape in the figure is the unfolded shape of the support mechanism. When it is necessary to install and disassemble the nanofiltration membrane 13, the support mechanism is pulled out, that is, the slide bar 15 slides outward in the positioning block 14. Since the shaft block 18 and the shaft plate 17 are provided with a central shaft 25, the central shaft 25 is used to sleeve a torsion spring, and the torsion spring is installed on the central shaft 25. At this time, under the influence of the torsion spring, the shaft block 18 will automatically flip upward, that is, the first support column 20 and the second support column 21 flip, and a stopper 29 is fixed to the top of the shaft plate 17. Under the influence of the stopper 29, the flipping angle of the shaft block 18 will be blocked by the stopper 29, so that the flipping position of the shaft block 18 remains vertical to the shaft plate 17, that is, 90°. At this time, when installing the nanofiltration membrane 13, the nanofiltration membrane 13 is pushed into the inside of the housing 10, and the arc bracket 22 drags the bottom of the nanofiltration membrane 13. In this way, when installing the nanofiltration membrane 13, there is no need for the staff to manually drag the bottom of the nanofiltration membrane or require multiple people to install it, thereby improving the convenience of installation of the nanofiltration membrane 13.

[0031] Further references Figure 2 and Figure 4 When shrinking the support mechanism, it is only necessary to push the slide bar 15 inward. In the first stage, the first support column 20 will contact one end of the outer shell 10. Continuing to push the slide bar 15 inward is the second stage, until the shaft block 18 remains parallel to the shaft plate 17, and the shrinkage is completed. The thickness of the first support column 20 is greater than the thickness of the second support column 21, and the height of the first support column 20 is just above the bottom of the outer shell 10 when the support mechanism is completely shrunk.

[0032] Further references Figure 2 and Figure 3A link column 23 is provided on the side of the shaft plate 17. When there are two or more shells 10, the supporting mechanism on the shell 10 is connected by the link column 23. A first handle 24 is provided below the link column 23. The supporting mechanism can be directly pulled out by the first handle 24. This structure can adapt to the combination and stacking of multiple shells 10 and is suitable for continuous desalination of polypeptides. Since the first handle 24 is at the bottom, the staff only needs to hook out the first handle 24 with their toes to easily pull out the supporting mechanism.

[0033] Embodiment 2:

[0034] A magnetic block 26 is disposed at one end of the slide bar 15 near the bridge block 16. When the support mechanism is fully retracted, the magnetic block 26 will be adsorbed on the positioning block 14 to prevent the support mechanism from being ejected due to the force generated by the torsion spring.

[0035] Furthermore, a U-shaped plate 27 is installed above the bridging block 16, and a second handle 28 is installed on the side of the U-shaped plate 27. This structure can be applicable to a housing 10. It only needs to connect the U-shaped plate 27 to the top of the shaft plate 17. The supporting mechanism can be easily pulled out through the second handle 28. Since the second handle 28 is at the bottom, the staff only needs to hook the second handle 28 with the toes to pull out the supporting mechanism.

[0036] In the above embodiment, the support mechanism is made of lightweight plastic material. The plastic material can reduce the burden of the support mechanism on the housing 10, making the structure light. If the plastic material is damaged, it can be easily replaced and the overall cost will be reduced accordingly. The slide rod 15 needs to be made of metal material with good hardness to prevent bending and deformation due to force.

[0037] The specific implementation process of the above embodiment is as follows:

[0038] When the support mechanism is unfolded, the support mechanism is pulled out, that is, the slide bar 15 slides outward in the positioning block 14. Since the central shaft 25 is installed on the shaft block 18 and the shaft plate 17, the central shaft 25 is used to sleeve a torsion spring. At this time, under the influence of the torsion spring, the shaft block 18 will flip upward, that is, the first support column 20 and the second support column 21 will flip, and a stopper 29 is fixed on the top of the shaft plate 17. Under the influence of the stopper 29, the flipping angle of the shaft block 18 will be blocked by the stopper 29, so that the flipping position of the shaft block 18 is kept vertical to the shaft plate 17, that is, 90°. At this time, when the nanofiltration membrane 13 is installed, the nanofiltration membrane 13 is pushed into the housing 10, and the arc bracket 22 drags the bottom of the nanofiltration membrane 13;

[0039] When the support mechanism contracts, the slide bar 15 is pushed inwardly. In the first stage, the first support column 20 will contact one end of the outer shell 10. Continuing to push the slide bar 15 inwardly is the second stage until the shaft block 18 remains parallel to the shaft plate 17, and the contraction is completed. The thickness of the first support column 20 is greater than the thickness of the second support column 21. The height of the first support column 20 is just above the bottom of the outer shell 10 when the support mechanism completes the contraction.

[0040] The above embodiments are only exemplary embodiments of the present invention and are not intended to limit the present invention. The protection scope of the present invention is defined by the claims. Various modifications or equivalent substitutions may be made to the present invention within the essence and protection scope of the present invention. Such modifications or equivalent substitutions shall also be deemed to fall within the protection scope of the present invention.

[0041] In the description of the present utility model, it should be noted that the terms "inside", "front", "back", "left", "right" and the like indicate directions or positional relationships based on the directions or positional relationships shown in the attached circles, or the directions or positional relationships in which the utility model product is usually placed when in use, and are only used to facilitate the description of the present utility model and simplify the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction. Therefore, these terms indicating directions or positional relationships cannot be understood as limiting the present utility model.

[0042] In the description of the present invention, it is further explained that, unless otherwise clearly specified and limited, the terms "disposed" and "connected" should be understood in a broad sense. For example, these terms can indicate a fixed connection, a detachable connection, or an integral connection between elements; they can also indicate a mechanical connection, an electrical connection; they can also indicate a direct connection or an indirect connection through an intermediate medium. For ordinary technicians in this field, the specific meanings of these terms in the present invention can be understood according to specific circumstances.

Claims

1. A polypeptide continuous desalination device, comprising a housing (10), a connecting pipe (11) installed at the rear of the housing (10), a liquid inlet (12) provided on one side of the connecting pipe (11), and a nanofiltration membrane (13) detachably installed inside the housing (10), characterized in that: It also includes a supporting mechanism provided below the housing (10), the supporting mechanism being used to support the nanofiltration membrane (13) during installation; The support mechanism comprises a positioning block (14) and a sliding rod (15), wherein two positioning blocks (14) are fixed below the housing (10), a sliding rod (15) is slidably mounted on the positioning block (14), one end of the sliding rod (15) is fixedly connected to a bridging block (16), an axis plate (17) is symmetrically mounted on the bridging block (16), one side of the axis plate (17) is rotatably connected to an axis block (18), a rectangular block (19) is fixed on the top of the axis block (18), and a first supporting column (20) and a second supporting column (21) are mounted on both sides of the rectangular block (19); the tops of the first supporting column (20) and the second supporting column (21) are arc-shaped brackets (22).

2. A polypeptide continuous desalination device according to claim 1, characterized in that: The thickness of the first support column (20) is greater than the thickness of the second support column (21).

3. A polypeptide continuous desalination device according to claim 2, characterized in that: A central shaft (25) is mounted on the shaft block (18) and the shaft plate (17), and a torsion spring is sleeved on the central shaft (25).

4. A polypeptide continuous desalination device according to claim 2, characterized in that: A stopper (29) is fixed on the top of the shaft plate (17).

5. A polypeptide continuous desalination device according to claim 4, characterized in that: A link column (23) is provided on the side of the shaft plate (17), and a first handle (24) is provided below the link column (23).

6. A polypeptide continuous desalination device according to claim 1, characterized in that: One end of the slide bar (15) is provided with a magnetic block (26) close to the bridge block (16), a U-shaped plate (27) is installed above the bridge block (16), and a second handle (28) is installed on the side of the U-shaped plate (27).

7. A polypeptide continuous desalination device according to claim 1, characterized in that: The support mechanism is made of lightweight plastic.

Images