Slide device for immunohistochemical experiment

Abstract

The utility model discloses an immunohistochemical experiment slide device, which belongs to the technical field of medical detection and comprises a taking plate, a groove is arranged at the top of the taking plate, label paper is attached to the inside of the groove, a clamping groove is arranged at the bottom of one side of the taking plate, a comparison plate is fixed on the other side of the taking plate, and the label paper is attached to the inside of the clamping groove. A sealing groove is formed in the side, close to the taking plate, of the comparison plate, a sealing plate is movably connected to the top of the taking plate, a clamping strip is fixed to the bottom of the end, close to the clamping groove, of the sealing plate, and a sealing strip matched with the sealing groove in size is fixed to the side, close to the sealing groove, of the sealing plate. According to the utility model, through the cooperative use of the taking plate, the groove, the label paper, the clamping groove, the comparison plate, the sealing groove, the sealing plate, the clamping strip, the sealing strip, the pressing sheet and the detection sheet, the label content on the slide can be replaced, the label can be better protected, the definition of the label content is prevented from being influenced by pinching abrasion, and thus the accuracy of experimental detection is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of medical detection, in particular to an immunohistochemistry experiment slide device. Background Art

[0002] Immunohistochemistry, also known as immunohistochemistry, is the application of antigen-antibody reaction. Through chemical reaction, the color developer (fluorescein, enzyme, metal ion, isotope) of the labeled antibody is used to develop color to determine the antigen (peptide and protein) in the tissue cells, and to conduct localization, qualitative and relative quantitative research on it. Immunohistochemistry experiments usually include sample preparation, antigen repair, blocking and antibody incubation, color development, sealing, photography and image analysis steps. When it comes to the sealing step, neutral gum sealing is required. Specifically, an appropriate amount of neutral gum sealing is required to be dripped on the slide with the sample fixed, and a cover glass is covered. The slide and the cover glass are bonded together by neutral gum, and the biological tissue sections are sealed for long-term preservation. After sealing, in order to prevent the cover glass from moving freely relative to the slide, the slide covered with the cover glass needs to be dried before it can be photographed under a microscope.

[0003] For example, the utility model with application number 202020607818.0 discloses a slide for immunohistochemistry detection, which can ensure that each section has a corresponding positive control tissue. The preparation process not only complies with the quality management system of 15189, but also greatly shortens the time, simplifies the process, improves efficiency, and unifies the standards. The anti-slide ensures that the positive control tissue has strong adhesion in the early stage, ensures that the slide does not fall off during the later staining process, and at the same time ensures the antigen retention time of the positive control, ensures the timeliness of the antigen, and prevents the degradation of the positive control chip.

[0004] Similar to the above application, there are still some shortcomings:

[0005] The required marked text is directly recorded on the note portion of the slide used for immunohistochemistry detection. The components lack protection for the marked text, and the marked text is easily scratched during operation. In addition, it is not convenient to change the experimental marked text, and cannot well meet people's experimental use needs.

[0006] Therefore, an immunohistochemistry experiment slide device is designed to optimize the above problems. Utility Model Content

[0007] The main purpose of the utility model is to provide an immunohistochemistry experiment slide device to solve the related technical problems raised in the above background technology.

[0008] The purpose of the utility model can be achieved by adopting the following technical solutions:

[0009] An immunohistochemistry experiment slide device comprises a picking plate, wherein a groove is provided on the top of the picking plate, label paper is attached to the inside of the groove, a card slot is provided on the bottom of one side of the picking plate, a comparison plate is fixed to the other side of the picking plate, a sealing groove is provided on the side of the comparison plate close to the picking plate, a sealing plate is movably connected to the top of the picking plate, a card strip is fixed to the bottom of the sealing plate close to one end of the card slot, a sealing strip matching the size of the sealing groove is fixed on the side of the sealing plate close to the sealing groove, and a detection sheet is fixed to the side of the comparison plate away from the picking plate.

[0010] Preferably: a temperature insulation layer is fixed at the bottom of the detection sheet, and an insulating layer is fixed at the bottom of the temperature insulation layer.

[0011] Preferably, a coating groove is provided at the bottom of one end of the insulating layer, a magnetic film is arranged inside the coating groove, and a protective sheet is fixed at the bottom of the insulating layer.

[0012] Preferably, scale lines are evenly arranged on one side of the detection sheet close to the temperature insulation layer, and micropores are arranged on the detection sheet.

[0013] Preferably, pressing sheets are symmetrically fixed on both sides of the sealing plate, and anti-slip grooves are arranged on the outer sides of the pressing sheets.

[0014] Preferably: the outer side of the sealing strip and the outer side of the clamping strip are both provided with an anti-corrosion layer, and the sealing strip is a rubber strip.

[0015] The beneficial effects of the utility model are:

[0016] The utility model provides an immunohistochemistry experiment slide device, which can conveniently replace the label content on the slide through the coordinated use of a taking plate, a groove, a label paper, a card slot, a comparison plate, a sealing groove, a sealing plate, a card strip, a sealing strip, a pressing sheet and a detection sheet, and has a better protective effect on the label content, avoiding the influence of hand-held or pinching wear on the clarity of the label content, thereby improving the accuracy of experimental detection;

[0017] Through the use of the temperature insulation layer and the insulating layer, the temperature insulation layer prevents the external temperature change from affecting the sample, maintains its stability, and reduces the interference of temperature factors on the experimental results. The setting of the insulating layer reduces the influence of static electricity on the sample and improves the safety of the experiment, thereby improving the practicality of the immunocombination experiment slide device;

[0018] Through the coordinated use of the coating groove, magnetic film and protective sheet, the coating groove attaches the magnetic film to the coating groove through a coating process, so that the glass slide as a whole has a certain adsorption magnetic force, which is convenient for placing the glass slide on a metal or magnetic glass slide fixing rack, facilitating the collection and placement of the glass slide, and also improving the stability of placement. The protective sheet plays a certain protective role on the magnetic film, reducing the increase in the number of uses and the reduction of magnetic force due to chemical corrosion. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the structure of the utility model;

[0020] Figure 2 For the utility model Figure 1 A magnified view of the structure at center;

[0021] Figure 3 It is a schematic diagram of the detection sheet of the present utility model.

[0022] In the figure: 1. Pick-up plate; 2. Groove; 3. Label paper; 4. Card slot; 5. Comparison plate; 6. Sealing groove; 7. Sealing plate; 8. Card strip; 9. Sealing strip; 10. Pressing sheet; 11. Detection sheet; 12. Insulation layer; 13. Insulation layer; 14. Laminating groove; 15. Magnetic film; 16. Protective sheet; 17. Scale line. DETAILED DESCRIPTION

[0023] In order to make the technical solution of the utility model more clear and specific to those skilled in the art, the utility model is further described in detail below in conjunction with embodiments and drawings, but the implementation methods of the utility model are not limited thereto.

[0024] Embodiment 1

[0025] like Figure 1-Figure 3 As shown, this embodiment provides an immunohistochemistry experiment slide device, including a picking plate 1, a groove 2 is provided on the top of the picking plate 1, a label paper 3 is attached to the inside of the groove 2, a card slot 4 is provided at the bottom of one side of the picking plate 1, a comparison plate 5 is fixed to the other side of the picking plate 1, a sealing groove 6 is provided on the side of the comparison plate 5 close to the picking plate 1, a sealing plate 7 is movably connected to the top of the picking plate 1, a card strip 8 is fixed to the bottom of the sealing plate 7 close to one end of the card slot 4, a sealing strip 9 matching the size of the sealing groove 6 is fixed to the side of the sealing plate 7 close to the sealing groove 6, a detection sheet 11 is fixed to the side of the comparison plate 5 away from the picking plate 1, a temperature insulation layer 12 is fixed to the bottom of the detection sheet 11, and an insulating layer 13 is fixed to the bottom of the temperature insulation layer 12.

[0026] Place or stick the label paper 3 with marked text in the groove 2, cover the top of the taking plate 1 with the sealing plate 7, press down the sealing strip 9 at one end of the sealing plate 7 and insert it into the sealing groove 6, then press down the other end of the sealing plate 7 to make the card strip 8 snap into the card groove 4, when replacing the label paper 3, the sealing plate 7 can be directly removed for replacement, the thermal insulation layer 12 prevents the external temperature change from affecting the sample, maintains its stability, and reduces the interference of temperature factors on the experimental results, and the setting of the insulating layer 13 reduces the influence of static electricity on the sample.

[0027] Embodiment 2

[0028] In this embodiment, if Figure 1-Figure 3 As shown, a coating groove 14 is opened at the bottom of one end of the insulating layer 13 , a magnetic film 15 is arranged inside the coating groove 14 , and a protective sheet 16 is fixed at the bottom of the insulating layer 13 .

[0029] The coating groove 14 attaches the magnetic film 15 to the coating groove 14 through a coating process, so that the glass slide as a whole has a certain adsorption magnetic force. The glass slide is placed on a glass slide fixing frame made of metal material or magnetism, which is convenient for collecting and placing the glass slide, and the protective sheet 16 plays a certain protective role on the magnetic film 15.

[0030] In this embodiment, scale lines 17 are evenly arranged on one side of the detection sheet 11 close to the temperature insulation layer 12 , and microholes are arranged on the detection sheet 11 .

[0031] The scale line 17 is arranged on the reverse side of the detection sheet 11 to facilitate the measurement of the size of the sample and is beneficial for observation. The arrangement of the microholes increases the attachment surface of the glass slide, facilitates the attachment of the sample and improves the efficiency of the reaction.

[0032] In this embodiment, pressing sheets 10 are symmetrically fixed on both sides of the sealing plate 7 , and anti-slip grooves are arranged on the outer sides of the pressing sheets 10 .

[0033] The arrangement of the pressing sheet 10 increases the convenience of taking out the slide and facilitates the taking out of the slide.

[0034] In this embodiment, the outer sides of the sealing strip 9 and the outer sides of the clamping strip 8 are both provided with anti-corrosion layers, and the sealing strip 9 is a rubber strip.

[0035] The anti-corrosion layer is provided to improve the protective effect of the outer side of the card strip 8 and the sealing strip 9, and reduce the overhead view of the card strip 8 and the sealing strip 9 by chemicals during the experiment. The provision of the rubber strip facilitates the sealing strip 9 to be engaged in the sealing groove 6, and can also play a waterproof sealing role.

[0036] The above is only a further embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the scope disclosed by the present invention according to the technical solution and concept of the present invention, which fall within the protection scope of the present invention.

Claims

1. An immunohistochemistry experiment slide device, characterized in that: The invention comprises a pick-up plate (1), wherein a groove (2) is provided at the top of the pick-up plate (1), a label paper (3) is attached to the inside of the groove (2), a card slot (4) is provided at the bottom of one side of the pick-up plate (1), a comparison plate (5) is fixed to the other side of the pick-up plate (1), a sealing groove (6) is provided on the side of the comparison plate (5) close to the pick-up plate (1), a sealing plate (7) is movably connected to the top of the pick-up plate (1), a card strip (8) is fixed to the bottom of the sealing plate (7) close to one end of the card slot (4), a sealing strip (9) matching the size of the sealing groove (6) is fixed to the side of the sealing plate (7) close to the sealing groove (6), and a detection sheet (11) is fixed to the side of the comparison plate (5) away from the pick-up plate (1).

2. The immunohistochemistry experiment slide device according to claim 1, characterized in that: A temperature insulation layer (12) is fixed to the bottom of the detection sheet (11), and an insulating layer (13) is fixed to the bottom of the temperature insulation layer (12).

3. The immunohistochemistry experiment slide device according to claim 2, characterized in that: A coating groove (14) is provided at the bottom of one end of the insulating layer (13), a magnetic film (15) is arranged inside the coating groove (14), and a protective sheet (16) is fixed at the bottom of the insulating layer (13).

4. The immunohistochemistry experiment slide device according to claim 2, characterized in that: The detection sheet (11) is evenly provided with scale lines (17) on one side close to the temperature insulation layer (12), and micropores are provided on the detection sheet (11).

5. The immunohistochemistry experiment slide device according to claim 1, characterized in that: Pressing sheets (10) are symmetrically fixed on both sides of the sealing plate (7), and anti-slip grooves are arranged on the outer sides of the pressing sheets (10).

6. The immunohistochemistry experiment slide device according to claim 1, characterized in that: The outer sides of the sealing strip (9) and the outer sides of the clamping strip (8) are both provided with anti-corrosion layers, and the sealing strip (9) is a rubber strip.

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