Split type centrifugal micro-fluidic chip

Abstract

The utility model discloses a fragmentation type centrifugal micro-fluidic chip, which comprises a tray body, a plurality of chip bodies and a plurality of chip bodies, the tray body is provided with a rotating center, the tray body is provided with a plurality of bearing surfaces around the rotating center, and each bearing surface is provided with a pin column structure; the plurality of centrifugal micro-fluidic discs are respectively supported on the supporting surfaces; a pin hole structure is arranged on the contact surface, opposite to the disc support body, of the centrifugal micro-fluidic disc, and the pin hole structure is matched with the pin column structure. When the centrifugal micro-fluidic disc is placed on the disc support, the pin hole structure on the centrifugal micro-fluidic disc is matched with the pin column structure on the disc support body, so that accurate positioning and stable rotation are kept.

Description

Technical Field

[0001] The utility model relates to a centrifugal microfluidic chip, in particular to a sliced ​​centrifugal microfluidic chip. Background Art

[0002] Centrifugal microfluidic chips can integrate a series of basic operation units involved in the fields of chemistry and biology, such as sample preparation, reaction, separation, and detection, into a small chip. At the same time, the network formed by the microfluidic channels can run through the entire system, with the advantages of precision, high efficiency, miniaturization of instruments, low reagent consumption, and small sample usage.

[0003] A centrifugal microfluidic chip is usually provided with multiple detection units, each detection unit is usually designed with multiple flow channels, the sample to be detected is distributed into multiple reaction chambers, and multiple items are detected on the same sample.

[0004] Centrifugal microfluidic chips are divided into sliced ​​and whole-chip types. Unlike the whole-chip centrifugal microfluidic chip in which multiple detection units are formed on a whole chip body, the sliced ​​centrifugal microfluidic chip includes several centrifugal microfluidic discs and disc trays for supporting these centrifugal microfluidic discs. By setting the detection units of several centrifugal microfluidic discs to adopt the same structure, the same items of multiple samples can be placed on one disc tray for detection; or by setting the detection units on several centrifugal microfluidic discs to be different, multiple items of a single sample can be placed on one disc tray for detection.

[0005] How to ensure that the centrifugal microfluidic disk remains stable on the disk holder during high-speed rotation is an urgent problem to be solved in this field.

[0006] The information disclosed in this background technology section is only intended to increase the understanding of the overall background of the utility model, and should not be regarded as acknowledging or suggesting in any form that the information constitutes the prior art already known to ordinary technicians in this field. Utility Model Content

[0007] Purpose of the utility model: The technical problem to be solved by the utility model is to provide a sliced ​​centrifugal microfluidic chip that can maintain overall stability during rotation in view of the deficiencies in the prior art.

[0008] In order to solve the above technical problems, the utility model discloses a sliced ​​centrifugal microfluidic chip, which comprises:

[0009] A tray body, wherein the tray body has a rotation center, and the tray body is provided with a plurality of supporting surfaces around the rotation center, and each of the supporting surfaces is provided with a pin structure;

[0010] And a plurality of centrifugal microfluidic discs are respectively supported on the supporting surface; a pin hole structure is arranged on the contact surface of the centrifugal microfluidic disc and the disc support body which is arranged opposite to each other, and the pin hole structure matches the pin column structure.

[0011] Specifically, each of the centrifugal microfluidic discs is a fan-shaped structure.

[0012] Further, the centrifugal microfluidic disc includes a notch, and the notches are respectively arranged at two opposite ends of the outer edge of the side of the centrifugal microfluidic disc opposite to the disc holder body along the arc direction. Correspondingly, the disc holder body includes a stop protrusion, and a stop protrusion is arranged at a position corresponding to the notch on the supporting surface of the disc holder body, and the stop protrusion cooperates with the notch.

[0013] Specifically, the stop protrusion is provided with a concave arc surface matching with the notch.

[0014] Furthermore, the tray body further comprises a reinforcement portion, and the reinforcement portion is formed in a region between two adjacent supporting surfaces of the tray body, and the reinforcement portion is higher than the supporting surface.

[0015] Specifically, the reinforcement portion is arranged to extend radially outward.

[0016] Specifically, each of the stop protrusions extends to the adjacent reinforcement portion.

[0017] Specifically, the tray body includes a through groove, and the through groove is opened on the supporting surface.

[0018] Specifically, the through groove is located in the middle of the supporting surface.

[0019] Specifically, the tray body includes a connecting component for connecting with the detection device, and the connecting component is arranged in the middle of the tray body.

[0020] Beneficial effects:

[0021] 1) When placing the centrifugal microfluidic disc, the pin hole structure on the centrifugal microfluidic disc and the pin column structure on the disc holder body cooperate with each other to maintain accurate positioning and stable rotation.

[0022] 2) The utility model prevents the centrifugal microfluidic disk from falling out of the disk tray body when the pin structure fails, thereby further improving the stability during rotation, by cooperating with the notch on the centrifugal microfluidic disk and the stop protrusion on the disk tray body.

[0023] 3) The utility model can quickly remove the centrifugal microfluidic disc by lifting the centrifugal microfluidic disc from the bottom of the disc holder body. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific implementation methods, and the above and / or other advantages of the present invention will become more clear.

[0025] Figure 1 It is a schematic diagram of the assembly structure of the disc holder body and a centrifugal microfluidic disc disclosed in the first embodiment of the utility model.

[0026] Figure 2 for Figure 1 The diagram is a partial enlarged schematic diagram of the assembly structure of the disk holder body and a centrifugal microfluidic disk.

[0027] Figure 3 for Figure 1 The front structural schematic diagram of the tray body is shown.

[0028] Figure 4 for Figure 1 The back structural schematic diagram of the tray body is shown.

[0029] Figure 5 for Figure 1 Schematic diagram of the front structure of the centrifugal microfluidic disk shown.

[0030] Figure 6 for Figure 1 Schematic diagram of the back structure of the centrifugal microfluidic disk shown.

[0031] Description of the accompanying drawings:

[0032] 1. Disc holder body; 11. Rotation center; 12. Supporting surface; 13. Pin structure; 14. Through groove; 15. Connecting component; 16. Reinforcement part; 17. Stop protrusion; 171. Arc surface; 2. Centrifugal microfluidic disc; 21. Contact surface; 22. Pin hole structure; 23. Recess. DETAILED DESCRIPTION

[0033] Example 1

[0034] See also Figures 1 to 6 The utility model discloses a sliced ​​centrifugal microfluidic chip, which includes a tray body 1 and six centrifugal microfluidic discs 2. The tray body 1 has a rotation center 11. The tray body 1 is provided with six supporting surfaces 12 around the rotation center 11. Three pin structures 13 are provided on each supporting surface 12. The six centrifugal microfluidic discs 2 are supported on the supporting surfaces 12 respectively. A pin hole structure 22 is provided on a contact surface 21 of the centrifugal microfluidic disc 2 and the tray body 1, and the pin hole structure 22 matches the pin structure 13.

[0035] When the centrifugal microfluidic disc 2 is placed in the utility model, the pin hole structure on the centrifugal microfluidic disc 2 cooperates with the pin column structure 13 on the disc holder body 1 to maintain accurate positioning and stable rotation.

[0036] It should be understood that the number of the centrifugal microfluidic disc 2 and the supporting surface 12 is not limited to six, and can be increased or decreased according to actual needs.

[0037] Likewise, the number of the pin structures 13 is not limited to three and can be increased or decreased according to actual needs.

[0038] It should be understood that the centrifugal microfluidic disk 2 may include a detection unit, which may be a detection unit in any centrifugal microfluidic chip, such as a blood type antigen identification area in a microfluidic blood type antigen identification chip disclosed in CN116196991A.

[0039] Preferably, six centrifugal microfluidic disks 2 are arranged in a circular array around the rotation center 11 .

[0040] It should be understood that the six centrifugal microfluidic disks 2 may also be simply distributed in pairs symmetrically about the rotation center 11 .

[0041] Optional, see Figure 1 The pin hole structure 22 is a through hole to facilitate installation.

[0042] Specifically, see Figure 1 and Figure 5 , each centrifugal microfluidic disc 2 is a fan-shaped structure.

[0043] Further, see Figure 5 and Figure 6 The centrifugal microfluidic disc 2 is provided with notches 23 at two opposite ends of the outer edge of the side opposite to the disc holder body 1 along the arc direction. Figure 1 A stop protrusion 17 is provided on the supporting surface 12 of the tray body 1 at a position corresponding to the notch 23 , and the stop protrusion 17 cooperates with the notch 23 .

[0044] In this embodiment, the notch 23 on the centrifugal microfluidic disc 2 cooperates with the stop protrusion on the disc holder body 1 to further improve the stability during rotation.

[0045] When the pin structure 13 fails, the stopping protrusion 17 stops the centrifugal microfluidic disk 2 to prevent the centrifugal microfluidic disk 2 from slipping outward during centrifugation.

[0046] When the centrifugal microfluidic disk 2 is supported on the disk holder body 1 , in the height direction, the top surface of the stop protrusion 17 and the recess 23 form a gap space to ensure that the centrifugal microfluidic disk 2 is in contact with the supporting surface 12 .

[0047] Specifically, see Figure 1 and Figure 3 The stop protrusion 17 is provided with an inner concave arc surface 171 which cooperates with the notch 23 . The notch 23 is provided with an outer convex arc surface which cooperates with the inner concave arc surface 171 .

[0048] The stop protrusion 17 and the notch 23 are matched with each other through the inner concave arc surface 171 and the outer convex arc surface.

[0049] For further information, see Figure 1 , Figure 3 and Figure 4 The supporting surface 12 is provided with a through groove 14 .

[0050] In this embodiment, the centrifugal microfluidic disk 2 is lifted up from the bottom of the disk holder body 1, so that the centrifugal microfluidic disk 2 can be quickly removed.

[0051] More specifically, see Figure 1 , Figure 3 and Figure 4 The through groove 14 is located in the middle of the supporting surface 12 .

[0052] Specifically, see Figure 1 A connecting component 15 for connecting with a detection device is provided in the middle of the tray body 1.

[0053] Further, in order to increase the structural strength, see Figure 3 The tray body 1 further includes a reinforcement portion 16 . The region between two adjacent supporting surfaces 12 of the tray body 1 is formed with the reinforcement portion 16 . The reinforcement portion 16 is higher than the supporting surfaces 12 .

[0054] See also Figure 1 When the centrifugal microfluidic disk 2 is supported on the supporting surface 12 , the centrifugal microfluidic disk 2 is located between the two reinforcement portions 16 .

[0055] Specifically, see Figure 1 The reinforcement portion 16 extends radially outward from a side close to the rotation center 11 of the tray body 1 .

[0056] Preferably, see Figure 1 Each stop protrusion 17 extends to the adjacent reinforcement portion 16 to improve the structural strength of the stop protrusion 17 .

[0057] Example 2

[0058] Different from the embodiment 1, the centrifugal microfluidic discs 2 of this embodiment are all rectangular structures, which are not shown in the figure.

[0059] The utility model provides a thought and method for a sliced ​​centrifugal microfluidic chip. There are many methods and ways to implement the technical solution. The above is only the preferred implementation of the utility model. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the utility model. These improvements and modifications should also be regarded as the protection scope of the utility model. All components not specified in this embodiment can be implemented by existing technologies.

Claims

1. A sliced ​​centrifugal microfluidic chip, characterized in that: include: A tray body (1), the tray body (1) having a rotation center (11), the tray body (1) being provided with a plurality of supporting surfaces (12) around the rotation center (11), and each supporting surface (12) being provided with a pin structure (13); And a plurality of centrifugal microfluidic discs (2) respectively supported on the supporting surface (12); a pin hole structure (22) is provided on a contact surface (21) of the centrifugal microfluidic disc (2) and the disc support body (1) that is arranged opposite to each other, and the pin hole structure (22) matches the pin column structure (13).

2. The sliced ​​centrifugal microfluidic chip according to claim 1, characterized in that: Each of the centrifugal microfluidic discs (2) is a fan-shaped structure.

3. The sliced ​​centrifugal microfluidic chip according to claim 2, characterized in that: The centrifugal microfluidic disc (2) comprises a notch (23), and the notches (23) are respectively arranged at two opposite ends of the outer edge of one side of the centrifugal microfluidic disc (2) opposite to the disc tray body (1) in the arc direction; correspondingly, the disc tray body (1) comprises a stop protrusion (17), and a stop protrusion (17) is arranged at a position corresponding to the notch (23) on the supporting surface (12) of the disc tray body (1), and the stop protrusion (17) cooperates with the notch (23).

4. The sliced ​​centrifugal microfluidic chip according to claim 3, characterized in that: The stop protrusion (17) is provided with an inner concave arc surface (171) matching with the notch (23).

5. The sliced ​​centrifugal microfluidic chip according to claim 3 or 4, characterized in that: The tray body (1) further comprises a reinforcement portion (16), the reinforcement portion (16) being formed in a region between two adjacent supporting surfaces (12) of the tray body (1), and the reinforcement portion (16) being higher than the supporting surfaces (12).

6. The sliced ​​centrifugal microfluidic chip according to claim 5, characterized in that: The reinforcement portion (16) is arranged to extend radially outward.

7. The sliced ​​centrifugal microfluidic chip according to claim 6, characterized in that: Each of the stop protrusions (17) extends to the adjacent reinforcement portion (16).

8. The sliced ​​centrifugal microfluidic chip according to claim 1, characterized in that: The tray body (1) comprises a through groove (14), and the through groove (14) is arranged on the supporting surface (12).

9. The sliced ​​centrifugal microfluidic chip according to claim 8, characterized in that: The through groove (14) is located in the middle of the supporting surface (12).

10. The sliced ​​centrifugal microfluidic chip according to claim 1, characterized in that: The tray body (1) comprises a connecting component (15) for connecting with a detection device, and the connecting component (15) is arranged in the middle of the tray body (1).

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