Pipetting module for gene detection

Abstract

The utility model discloses a pipetting module for gene detection. The pipetting module comprises a base, the pressing plate is arranged in the base; the plurality of pipetting heads are arranged below the pressing plate in parallel; each pipetting head is internally provided with a pipetting needle which passes through the pressing plate through the same driving mechanism and then does piston motion in the pipetting head; each pipetting head and the corresponding pipetting needle are sealed through a sealing assembly, and each sealing assembly comprises a first sealing ring and a second sealing ring which are sequentially arranged on the outer wall of the corresponding pipetting needle in a sleeving mode from top to bottom; a guide gasket arranged on the pipetting needle in a sleeving manner is also arranged between the first sealing ring and the second sealing ring; according to the utility model, the pipetting needle and the pipetting head are subjected to double-layer sealing through the first sealing ring and the second sealing ring which are arranged up and down, so that when the pipetting needle performs piston motion in the pipetting head, the overall sealing performance is good; meanwhile, the guide gasket between the first sealing ring and the second sealing ring plays a role in guiding and lubricating the pipetting needle, so that normal pipetting is ensured.

Description

Technical Field

[0001] The utility model relates to the technical field of medical instruments, in particular to a liquid transfer module for gene detection. Background Art

[0002] With the development of science and technology, the level of medical technology has also been significantly improved. In medical, biological, biochemical and chemical laboratories, it is necessary to mix one solution with another solution, or transfer a solution to a specific location. In this process, a pipetting module is needed to transfer the solution.

[0003] The working principle of the pipetting module is to drive the pipette head to absorb and discharge liquid through the piston movement of the pipette needle in the pipette head. At present, the seal between the pipette needle and the pipette head is mostly sealed by a single O-ring. In this way, in the actual pipetting process, the sealing stability is poor and cannot meet the actual use requirements; secondly, since the top position of the pipette needle is fixed and limited during assembly, it cannot move freely and swing left and right, which may cause processing errors and assembly errors, thereby affecting the sealing during pipetting.

[0004] In addition, a single sealing ring is used to seal between the existing pipetting head and the suction tip, which is complicated to install and has high cost, and cannot meet actual usage requirements. Utility Model Content

[0005] The utility model aims to overcome the deficiencies of the prior art and provide a liquid transfer module for gene detection, which has good sealing performance during liquid transfer and is convenient for replacing the pipette tip with low cost.

[0006] In order to achieve the above-mentioned purpose, the technical solution adopted by the utility model is: a liquid transfer module for gene detection, comprising:

[0007] Pedestal;

[0008] A pressing plate, arranged in the base;

[0009] A pipetting head, wherein a plurality of the pipetting heads are arranged in parallel below the pressing plate;

[0010] A pipetting needle is provided in each of the pipetting heads and performs piston motion in the pipetting head after passing through the pressing plate through the same driving mechanism;

[0011] A sealing assembly, wherein each of the pipetting heads and the pipetting needle is sealed by a sealing assembly, wherein the sealing assembly comprises a first sealing ring and a second sealing ring which are sequentially sleeved on the outer wall of the pipetting needle; a guide gasket sleeved on the pipetting needle is further provided between the first sealing ring and the second sealing ring;

[0012] The suction tip is adapted to the bottom of the pipetting head, and the suction tip is driven by the piston movement in the pipetting head via the pipetting needle to suck and discharge liquid.

[0013] Preferably, the guide gasket is made of Teflon.

[0014] Preferably, an inner concave cavity for assembling a sealing component is provided in the pipetting head.

[0015] Preferably, a connecting block is provided in the base, and the driving mechanism is arranged in the base and drives the connecting block to rise and fall in the base; a plurality of fixed blocks arranged at intervals are provided at the bottom of the connecting block, and a accommodating cavity is formed between every two of the fixed blocks; the top of the pipetting needle is arranged in the accommodating cavity, the bottom of the pipetting needle passes through the accommodating cavity and is arranged in the pipetting head, and an adjustment gap is left between the top of the pipetting needle and the lower surface of the connecting block; a third sealing ring is also provided between the top of the pipetting needle and the fixed block.

[0016] Preferably, the pipette tip comprises a pipette tip body and a pipette tip head, and convex points are arranged on the inner circumference of the pipette tip head; wherein, when the pipette head is inserted into the pipette tip head, the pipette head is sealed with the pipette tip head through the convex points.

[0017] Preferably, there is a gap between the head of the pipette tip and the middle of the pipette head, and the head of the pipette tip and the bottom of the pipette head are adaptably connected.

[0018] Due to the application of the above technical solution, the utility model has the following advantages compared with the prior art:

[0019] 1. In the pipetting module for gene detection of the utility model, a double-layer seal is performed between the pipetting needle and the pipetting head by means of a first sealing ring and a second sealing ring arranged up and down, so that when the pipetting needle performs piston movement in the pipetting head, the overall sealing performance is good; at the same time, the guide gasket between the first sealing ring and the second sealing ring guides and lubricates the pipetting needle, ensuring the normal pipetting.

[0020] 2. An adjustment gap is left between the top of the pipette needle and the lower surface of the connecting block, so that the pipette needle can move freely and swing left and right, avoiding processing errors and assembly errors and ensuring sealing during pipetting.

[0021] 3. The inner circumference of the pipette head is provided with convex points, and the pipette head and the pipette head are sealed by the convex points, so that no additional sealing ring is needed for sealing, the cost is low, and only a small insertion force and push-out force are required. The small sealing area ensures the stability of the seal. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] The technical solution of the utility model is further described below in conjunction with the accompanying drawings:

[0023] Figure 1 This is a schematic diagram of the three-dimensional structure of an embodiment of the utility model;

[0024] Figure 2 for Figure 1 An internal cross-sectional view of

[0025] Figure 3 for Figure 2 A partial schematic diagram of

[0026] Figure 4 for Figure 3 A magnified view of part A in FIG.

[0027] Figure 5 for Figure 3 A magnified view of part B in FIG.

[0028] Figure 6 It is a partial schematic diagram of the connection between the suction head and the pipetting head in one embodiment of the utility model;

[0029] Figure 7 for Figure 6 The enlarged view of the C part in FIG.

[0030] Figure 8 for Figure 6 The enlarged view of the D part in FIG.

[0031] Wherein: base 1, pressing plate 2, pipetting head 3, pipetting needle 4, driving mechanism 5, sealing assembly 6, suction head 7, connecting block 10, fixing block 11, accommodating cavity 12, third sealing ring 13, inner concave cavity 30, first sealing ring 60, second sealing ring 61, guide gasket 62, suction head body 70, suction head 71, protrusion 72, gap 80. DETAILED DESCRIPTION

[0032] In order to enable those skilled in the art to better understand the solution of the present application, the technical solution in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work should fall within the scope of protection of the present application.

[0033] The utility model provides a pipetting module for gene detection, so as to solve the problem in the prior art that when the pipetting module is working, the sealing between the pipetting needle and the pipetting head is poor when the pipetting needle makes up and down piston movement, thereby causing the pipetting operation to fail to meet actual use requirements.

[0034] For ease of understanding, the specific process in the embodiments of the present application is described below. Figures 1 to 4 A pipetting module for gene detection in the embodiment of the present application comprises a base 1, a pressing plate 2, a pipetting head 3, a pipetting needle 4, a sealing assembly 6 and a suction tip 7. The pressing plate 2 is arranged transversely inside the base 1; a plurality of the pipetting heads 3 are arranged in parallel below the pressing plate 2; and a pipetting needle 4 is arranged in each of the pipetting heads 3, which passes through the pressing plate 2 through the same driving mechanism 5 and then performs piston motion in the pipetting head 3.

[0035] Each of the pipetting heads 3 and the pipetting needle 4 is sealed by a sealing assembly 6, which includes a first sealing ring 60 and a second sealing ring 61 which are sequentially sleeved on the outer wall of the pipetting needle 4; a guide gasket 62 sleeved on the pipetting needle is also provided inside the first sealing ring 60 and the second sealing ring 61. The suction head 7 is adapted to the bottom of the pipetting head 2, and the suction head 7 is driven by the piston movement of the pipetting needle 4 to suck and discharge liquid.

[0036] The pipetting module for genetic testing of the present invention performs double-layer sealing between the pipetting needle 4 and the pipetting head 3 by means of a first sealing ring 60 and a second sealing ring 61 which are arranged up and down, so that when the pipetting needle 4 performs up and down piston movement in the pipetting head 3, the overall sealing can be guaranteed; at the same time, due to the presence of the guide gasket 62, it can guide the up and down movement of the pipetting needle 3 in the pipetting head 4, avoiding the pipetting needle from tilting with the inner wall of the pipetting head when moving downward, ensuring that the pipetting can be carried out normally, and the guide gasket 62 can also play a certain lubricating role.

[0037] based on Figure 4 In the present embodiment, the first sealing ring 60 and the second sealing ring 61 are both O-rings, but they may be other types of sealing rings. Secondly, the guide gasket 62 is made of Teflon, which is resistant to acids, alkalis, and various organic solvents and is almost insoluble in all solvents. Meanwhile, polytetrafluoroethylene is resistant to high temperatures and has an extremely low friction coefficient, which can well guide the pipette needle.

[0038] In addition, an inner cavity 30 for fitting the sealing component 6 is provided on the inner wall of the pipetting head 3, so as to place the sealing component 6 between the pipetting needle 4 and the inner cavity 30, so as to achieve good tightness after assembly.

[0039] As a preferred embodiment, based on Figure 2 , Figure 3 and Figure 5In the embodiment, a vertically arranged connecting block 10 is provided in the base 1, and the driving mechanism 5 is arranged in the base 1 and drives the connecting block 10 to rise and fall in the base 1. The bottom of the connecting block 10 is connected with a plurality of fixed blocks 11 arranged at intervals, and a receiving cavity 12 is formed between every two fixed blocks 11, and the receiving cavity 12 is in a T shape. The top of the pipetting needle 4 is arranged in the receiving cavity 12, and the bottom of the pipetting needle 4 passes through the receiving cavity 12 and is arranged in the pipetting head 3 to perform up and down piston movement, and an adjustment gap is left between the top of the pipetting needle 4 and the lower surface of the connecting block 10. If an adjustment gap is left here, the pipetting needle 4 can move freely when moving up and down, and swing left and right, which can avoid processing errors and assembly errors, thereby ensuring the sealing during pipetting.

[0040] In addition, a third sealing ring 13 is provided between the top of the pipette needle 4 and the fixed block 11. After the third sealing ring 13 is added, the top of the pipette needle can be limited to ensure the processing verticality of the pipette needle and avoid assembly errors, which will not cause the pipette needle 4 to be skewed during assembly, and the overall sealing is better.

[0041] As a preferred embodiment, based on Figures 6 to 8 In the embodiment, the pipette tip 7 includes a pipette tip body 70 and a pipette tip head 71, and a convex point 72 is provided on the inner circumference of the pipette tip head 71. When the bottom of the pipette tip 3 is inserted into the pipette tip head 71, the seal between the pipette tip 3 and the pipette tip head 71 is sealed by the convex point 72, so that no additional sealing ring is required for sealing, and only a small insertion force and a small push-out force are required, so that a small sealing area ensures the stability of the seal and saves costs.

[0042] At the same time, a gap 80 is left between the tip head 72 and the middle of the pipette head 3, and the tip head 72 is adapted to be connected with the bottom of the pipette head 3, so that the verticality between the pipette head 3 and the tip 7 can be ensured to ensure normal pipetting.

[0043] As described above, the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit them. Although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present application.

Claims

1. A pipetting module for gene detection, characterized in that: include: Pedestal; A pressing plate, arranged in the base; A pipetting head, wherein a plurality of the pipetting heads are arranged in parallel below the pressing plate; A pipetting needle is provided in each of the pipetting heads and performs piston motion in the pipetting head after passing through the pressing plate through the same driving mechanism; A sealing assembly, wherein each of the pipetting heads and the pipetting needle is sealed by a sealing assembly, wherein the sealing assembly comprises a first sealing ring and a second sealing ring which are sequentially sleeved on the outer wall of the pipetting needle; a guide gasket sleeved on the pipetting needle is further provided between the first sealing ring and the second sealing ring; The suction tip is adapted to the bottom of the pipetting head, and the suction tip is driven by the piston movement in the pipetting head via the pipetting needle to suck and discharge liquid.

2. The liquid transfer module for gene detection according to claim 1, characterized in that: The guide gasket is made of Teflon.

3. The liquid transfer module for gene detection according to claim 1, characterized in that: An inner concave cavity for fitting and assembling a sealing component is provided in the pipetting head.

4. The liquid transfer module for gene detection according to claim 1, characterized in that: A connecting block is provided in the base, and the driving mechanism is arranged in the base and drives the connecting block to rise and fall in the base; a plurality of fixed blocks arranged at intervals are provided at the bottom of the connecting block, and a accommodating cavity is formed between every two of the fixed blocks; the top of the pipetting needle is arranged in the accommodating cavity, and the bottom of the pipetting needle passes through the accommodating cavity and is arranged in the pipetting head, and an adjustment gap is left between the top of the pipetting needle and the lower surface of the connecting block; a third sealing ring is also provided between the top of the pipetting needle and the fixed block.

5. The liquid transfer module for gene detection according to claim 1, characterized in that: The pipette tip comprises a pipette tip body and a pipette tip head, wherein convex points are arranged on the inner circumference of the pipette tip head; wherein, when the pipette tip is inserted into the pipette tip head, the pipette tip is sealed with the pipette tip head via the convex points.

6. The liquid transfer module for gene detection according to claim 5, characterized in that: There is a gap between the head of the suction tip and the middle of the liquid transfer head, and the head of the suction tip is adaptively connected to the bottom of the liquid transfer head.

Images