37 results about "Mechanical pipette" patented technology

A sample loading device and a gene sequencer, the sample loading device comprising: a fixed seat assembly, a gland assembly and a cap assembly, the fixed seat assembly having a fixed position for placing a slide frame loaded with a biochip; the gland assembly is rotatably connected to the fixed seat assembly, and the gland assembly is further snap-connected with the fixed seat assembly to fix the slide frame in the fixed position, and the gland assembly is provided with a positioning hole for installing a pipette head; the cap assembly is detachably arranged on the gland assembly and covers the positioning hole, and the cap assembly is used for pressing the pipette head in the positioning hole to provide a pushing force for the liquid in the pipette head. The sample loading device of the present application can realize the fixation of the slide frame by the gland assembly and the fixed seat assembly, and the cap assembly arranged on the gland assembly can provide a pushing force for the liquid in the pipette head, promote the flow of the internal liquid, and be beneficial to the automatic liquid passing of the biochip.

A multifunctional pipette set includes a pipette module, a heater module and a magnetic module. The pipette module includes one or more pipette heads. The heater module has a first joint part, and the heater module configured to removably connect to the pipette module by coupling the first joint part to at least one of the plurality of pipette heads. The magnetic module has a second joint part, and the magnetic module configured to removably connect to the pipette module by coupling the second joint part to at least one of the plurality of pipette heads. The multifunctional pipette set can be further applied in an automatic detection machine.

This invention discloses a micro-volume liquid transfer system, a micro-volume liquid transfer method, and its application. The micro-volume liquid transfer system includes: a reservoir for storing the liquid to be transferred; a pipette tip made of a conductive material for picking up and transferring the liquid from the reservoir; a receiver made of a conductive material for receiving the liquid transferred by the pipette tip; a power supply electrically connected to the pipette tip for energizing the pipette tip to create a voltage difference between the pipette tip and the receiver; a controller electrically connected to the power supply for controlling the energization or de-energization of the pipette tip; and a drive assembly for driving the pipette tip to move, or for driving at least two of the movements of the reservoir, pipette tip, and receiver. The micro-volume liquid transfer system of this invention can transfer micro-volume liquids, is simple, fast, efficient, reliable, and accurate.

The utility model discloses a multi-caliber pipetting head. The multi-caliber pipetting head comprises a pipetting head body, the pipetting head body comprises a connecting sleeve, a connecting pipe, a pipette and a suction head, a sealing lantern ring is installed at the end of the pipette, the sealing lantern ring is made of an elastic silica gel material, a plurality of sets of cavities with different calibers are formed in the connecting pipe, and the connecting pipe is connected with the suction head. The pipettes can be matched with the sealing lantern rings installed at the ends to be installed in the multiple sets of cavities with different calibers of the connecting pipe, and through the arrangement of the connecting pipe, the pipettes and the suction heads, when various kinds of liquid with different properties need to be treated in a laboratory, the cavities with different calibers are formed in the connecting pipe to be matched with the pipettes for use, so that the liquid with different properties can be treated conveniently. The pipette can adapt to liquids with different viscosities and surface tensions through the design of the cavity and the use of the sealing ring, and meanwhile, residues of the liquids in the pipetting process can be reduced, so that the pipetting accuracy is improved.

The invention relates to a pipetting plate making system. The pipetting plate making system comprises a pipetting head module, pipetting device cleaning equipment and a pipetting arm, the pipetting head module comprises a pipetting mechanism, a liquid suction and spray driving mechanism and a pipetting head quick-changing device, the pipetting mechanism is provided with a suction head connecting part, and the pipetting mechanism is detachably connected with the liquid suction and spray driving mechanism through the pipetting head quick-changing device; the liquid sucking and spraying driving mechanism drives the liquid transferring mechanism to provide positive pressure or negative pressure for the suction head connecting part; the pipetting device cleaning equipment comprises a plurality of mutually independent cleaning channels, the water inlet mechanism is connected with the cleaning channels to input cleaning liquid, the first drainage mechanism is connected with the cleaning channels to discharge the cleaning liquid, and at least one pipetting suction head extends into each cleaning channel; the pipetting arm is in driving connection with the pipetting head module and is used for driving the pipetting head module to move to a preset working position; wherein the preset working positions comprise a sample plate liquid absorption position, a reaction plate liquid spraying position and a cleaning position. Multi-flux flexible use can be achieved, efficiency is high, and cross contamination is not prone to being generated.

A method of measuring the alignment of one or more pipetting tips in an automated pipetting system where the one or more pipetting tips are mounted on one or more adapters of a pipetting head approximately perpendicular to the pipetting head mounting surface is disclosed. The orifices at the end of the one or more pipetting tips are mapped with an image capture device having a sensor placed in face and distant of the orifices. The method sends the acquired data from mapping the orifices of the one or more pipetting tips to the data processor, generating an image of the orifices of the one or more pipetting tips, determining the center positions of orifices, and delivering alignment information for the one or more pipetting tips.

A pipetting system is disclosed that includes a pipette head including a multichannel air displacement system for aspirating and dispensing liquids, a pipetting system base that includes a linear guide system along which the pipette head may be moved vertically with respect to the pipetting system base, and counterbalance means for counterbalancing at least a portion of a weight of the pipette head.

The utility model relates to the technical field of pipetting equipment, in particular to mechanical arm-based pipetting equipment which comprises a base, an operation table is arranged at the top of the base, two mechanical arms are fixedly mounted at the top of the operation table, pipetting heads are fixedly mounted at the bottoms of the mechanical arms, and cleaning and disinfecting mechanisms are arranged on the left side and the right side of the operation table; the cleaning and disinfecting mechanism comprises a banister brush used for friction disinfection, a movable damping mechanism is arranged at the bottom of the operation table, a mechanical arm is started to drive a pipetting head to be inserted into a cleaning box, so that the pipetting head is immersed into alcohol, then a motor is started to drive a rotating cylinder to rotate, and the banister brush scrubs the pipetting head; therefore, during immersion, gaps of the pipetting head are brushed and disinfected, stubborn bacteria and viruses are prevented from remaining in the gaps, cross contamination is prevented, the accuracy and reliability of experimental results are prevented from being influenced, the disinfection effect is effectively improved, and the success of experiments is ensured.

The present invention provides a mechanical positioning multichannel pipettor, and relates to the field of pipettors, the mechanical positioning multichannel pipettor comprises a main body, a plurality of pipetting channels arranged on the main body, and pipetting heads arranged at one end of the main body and corresponding to the pipetting channels, and further comprises: an adjusting mechanism arranged in the main body, the adjusting mechanism comprises an adjusting slide block moving along the length direction of the main body; the positioning assembly comprises a positioning block, a guide sliding rail and a locking piece. The adjusting sliding block is arranged on one side of the positioning block, the guide sliding rail is fixedly arranged in the main body, and the positioning block is slidably arranged on the guide sliding rail; the locking piece is movably arranged on the main body, and the locking piece is provided with a locking position selectively matched with the positioning block and a releasing position separated from the positioning block; wherein the adjusting slide block is in transmission connection with the pipetting channel through the connecting assembly. The device has the advantages of being accurate in adjustment, reliable in locking, visual in operation and durable in structure. The accuracy and stability of spacing adjustment are ensured, and the use convenience is improved through visual indication and operation design.

A pipette for use with a pipetting head of a liquid dispensing apparatus, the pipette comprising a pipette tip 1100 having a distal end 1102 with dispensing aperture 1108 and a proximal end 1101 with

A laboratory automation apparatus with a liquid volume measurement functionality comprising a working table, a pipettor comprising a pipetting head with an electrode providing a capacitive sensor with a reference electrode. A robotic arm is configured to move the pipetting head above the working table. A processor is operatively coupled to the robotic arm, to the pipettor and to the electrode by an electronic circuit. A capillary is located on the working table having an opening for receiving a target amount of liquid from the pipettor to form an air-liquid meniscus in the capillary. The robotic arm is configured to hover the electrode over the capillary to detect a change in capacitance related to the position of the meniscus, and the processor is configured to calculate the transferred amount of liquid from the position of the meniscus in the capillary.

The current invention involves a method of isolating a pathogen from a food sample using an automated pipetting system to remove supernatant from centrifuge tubes down to a calibrated volume. The automated pipetting system includes an automated pipetting system with the capacity to determine the calibrated volume to prevent disturbing a biological mass at the bottom of the centrifuge tubes.

The application relates to the technical field of automatic pipetting, in particular to an automatic pipetting system which comprises a sleeve, the bottom end of the sleeve is integrally formed with a plug pipe, a suction pipe is inserted into the plug pipe, characterized in that: a pressure control pipe is arranged in the sleeve and communicated with the plug pipe, a piston which moves along the axial direction of the pressure control pipe is slidably embedded in the pressure control pipe, the position of the piston is adjusted and controlled through a threaded transmission structure, the top end of the sleeve is fixedly connected with a cover plate, and a socket which is communicated with and controlled by the outside is arranged on the top of the cover plate. According to the scheme, the pressure control pipe which is communicated with the plug pipe is arranged in the sleeve, a piston which is driven through a threaded structure is slidably embedded in the pressure control pipe, the position of the piston is conveniently controllable, in addition, the socket and the external control structure are docked on the outside of the sleeve, and the pipetting structure is conveniently controlled.

This utility model discloses a novel pipette, relating to the field of laboratory instruments. The technical solution includes a pipette body and a pipette tip detachably connected to the pipette body. A connecting tube is fixedly installed at the lower end of the pipette body, and the lower end of the connecting tube is tapered. The pipette tip is detachably connected to the tapered portion of the connecting tube. A groove is formed on the tapered portion of the connecting tube, and a locking tongue, shaped like a right-angled trapezoid, is slidably installed within the groove. The smaller bottom surface of the locking tongue faces the lower end of the connecting tube. A sliding hole is formed on the side wall of the connecting tube, with the axis of the sliding hole parallel to the axis of the connecting tube. A pressing rod is slidably installed inside the vertical tube, and the upper end of the pressing rod extends to the outside of the pipette body and is fixed to the release button of the pipette body. The beneficial effect of this utility model is that it makes the connection between the pipette and the pipette tip more stable and tight, thereby improving the fixation performance of the pipette tip and avoiding the problem of easy detachment.

The invention discloses a pipettor with a visual suck-back prevention warning structure, and relates to the technical field of pipettors, the pipettor comprises a shell and a pipettor main body, the bottom end of the shell is connected with the pipettor main body, and the bottom end of the pipettor main body is fixedly provided with a pipetting head. A blending mechanism is arranged in the shell and is driven by a left motor and a right motor, the outer sides of output shafts of the left motor and the right motor are connected with a first bevel gear and a half-tooth bevel gear respectively, and the half-tooth bevel gear is larger than the first bevel gear, that is, the half-tooth bevel gear can be in meshed connection with a second bevel gear and a third bevel gear; the first bevel gear can only be in meshed connection with the second bevel gear, so that two operation modes of unidirectional rotation and reciprocating rotation can be realized, the pipettor has more functions, namely, various different experiment operations can be completed on one pipettor, other instruments do not need to be replaced, and the experiment cost and the occupied space of the equipment are reduced.

An automated pipetting system includes a pipettor. The pipettor includes a pipetting channel, a first plunger mechanism operable to change a pressure in the pipetting channel to aspirate or dispense a liquid, and a second plunger mechanism operable to change the pressure in the pipetting channel to aspirate or dispense the liquid.

The invention relates to a high throughput pipetting plate making system. The high-throughput pipetting plate making system comprises a pipetting head module, a pipetting device cleaning device, a pipetting arm and a stacking device. Wherein the pipetting head module comprises a pipetting mechanism, a liquid sucking and spraying driving mechanism and pipetting head quick-changing equipment, and the pipetting mechanism is detachably connected with the liquid sucking and spraying driving mechanism through the pipetting head quick-changing equipment; the pipetting device cleaning equipment comprises a plurality of mutually independent cleaning channels, and at least one pipetting suction head extends into each cleaning channel; the pipetting arm drives the pipetting head module to move to a preset working position; wherein the preset working positions comprise a sample plate liquid absorption position, a reaction plate liquid spraying position and a cleaning position; the stacking device is used for storing consumables and carrying out consumable interaction on the consumables and the pipette head module. The system can be flexibly used in a multi-flux manner, is high in efficiency, is not liable to generate cross contamination, automatically and interactively takes and places consumables, improves the consumable feeding efficiency, improves the plate making efficiency, and guarantees the pipetting precision.

A pipetting head for a liquid dispensing apparatus for use with an array of pipettes, each pipette having a pipette tip 1100 and a plunger 1200 disposed within the pipette tip. The pipetting head has

The invention relates to an efficient sample reaction plate preparation platform. The efficient sample reaction plate preparation platform comprises a sample transfer module, a reagent adding module and a heat sealing module. The sample pipetting mechanism is detachably connected with the sample liquid sucking and spraying driving mechanism through the pipetting head quick-changing equipment; the reagent adding module comprises a reagent pipetting mechanism, a reagent pipetting needle and a reagent pipetting chamber which are communicated, the reagent pipetting chamber is provided with a reagent pipetting structure, and the reagent pipetting structure can provide pressure for the reagent pipetting chamber, so that a reaction reagent in the reagent pipetting chamber is sprayed out through the reagent pipetting needle; and the heat sealing module is used for sealing the reaction plate at the heat sealing station. The flux is not limited, the plate making speed is high, and sample evaporation loss and aerosol-mediated cross contamination are avoided.

An automated pipetting system includes a pipettor. The pipettor includes a pipetting channel, a first plunger mechanism operable to change a pressure in the pipetting channel to aspirate or dispense a liquid, and a second plunger mechanism operable to change the pressure in the pipetting channel to aspirate or dispense the liquid.

A pipette for use with a pipetting head of a liquid dispensing apparatus, the pipette comprising a pipette tip 1100 having a distal end 1102 with dispensing aperture 1108 and a proximal end 1101 with

A robotic arm of an automated pipetting system, comprising: a pipette tip adapter; a slide switch detecting the presence of a pipette tip on the pipette tip adapter, comprising: first and second supports sliding relative to each other along a movement axis between a first and a second position; an electrically conductive contact pad arranged on the first support; an electrically conductive terminal physically contactingly attached to the second support when the supports are in the first position, the terminal being a resilient and intrinsically stable first wiper extending along the movement axis, the first wiper not being in physical contact with the contact pad when the supports are in the second position, an electrical current being flowable between the first wiper and the contact pad when the supports are in the first position, the electrical current between the wiper and the contact pad being interrupted when the supports are in the second position. Use of a robotic arm in an automated pipetting system, the slide switch detecting the presence of a pipette tip on the pipette tip adapter. An automated pipetting system, comprising a robotic arm detecting the presence of a pipette tip on the pipette tip adapter.

An apparatus is configured to complementarily engage with a pipetting head of a liquid handling system such that movement of the pipetting head effects corresponding movement of the apparatus. The apparatus includes at least one engagement feature configured to mechanically and releasably engage a surface of a laboratory instrument article as a means of releasably coupling the laboratory instrument article to the apparatus. The laboratory instrument article has at least one complementarily engaging feature and optionally at least one release feature. With the laboratory instrument article seemingly within a receiving seat, the apparatus can be translated relative to the laboratory instrument article such that the engagement feature of the apparatus engages the release feature of the laboratory instrument article, thereby permitting release of the laboratory instrument article as the apparatus moves relative to the laboratory instrument article.

The utility model relates to a multi-layer pipette head storage box, which comprises a pipette head storage box and a plurality of pipette head carrying frames arranged in a stacked manner, an upper inserting block and a lower inserting block are convexly arranged at the upper part and the lower part of the two sides of each pipette head carrying frame, and the outer wall of the lower inserting block is connected with the inner wall of the upper inserting block of the adjacent pipette head carrying frame in an abutting manner. The adjacent pipette head carrying frames are directly connected, the pipette heads cannot be damaged during shaking, the adjacent lower-layer pipette heads cannot be taken up together when the pipette head carrying frames are replaced, and the pipette head carrying frame is very convenient to use.

An automatic liquid preparation system comprises a mounting bracket, a pipettor, a pipetting head device, a liquid taking turntable and a liquid injection turntable. The top of the mounting bracket is provided with a vertical sliding groove, and the pipettor is arranged in the vertical sliding groove. The pipettor is provided below the pipetting head device. The pipetting head device comprises a supporting box, a pipetting head, a horizontal sliding groove and a storage box. The pipetting head is arranged on the supporting box, the horizontal sliding groove is arranged on the mounting bracket, and the supporting box is slidably connected with the horizontal sliding groove. The storage box is arranged at one end of the horizontal sliding groove, and the other end of the horizontal sliding groove is located below the pipettor. The bottom of the mounting bracket is a bracket base, and the liquid injection turntable is arranged on the bracket base. The liquid taking turntable is arranged above the liquid injection turntable and coaxial with the liquid injection turntable. The liquid injection turntable is provided with a plurality of liquid injection pipes. The liquid taking turntable is provided with a liquid taking pipe. The automatic liquid preparation system in the technical solution is more accurate and efficient than the manual liquid preparation method, and is less likely to threaten the safety of personnel.

A pipetting head 100 comprising a pipette body mounting assembly 120 with an array of pipette body mounts, and a moveable pipette guide assembly 180 having a guide plate 182 comprising a plurality of

The invention relates to a high-throughput sample reaction plate preparation platform. The invention relates to a high-throughput sample reaction plate preparation platform. The high-throughput sample reaction plate preparation platform comprises a sample transfer module and a reagent adding module, and the sample pipetting mechanism is detachably connected with the sample liquid suction and spray driving mechanism through pipetting head quick-change equipment; the reagent adding module comprises a reagent pipetting mechanism, a reagent pipetting needle and a reagent pipetting chamber which are communicated, the reagent pipetting chamber is provided with a reagent pipetting structure, and the reagent pipetting structure can provide pressure for the reagent pipetting chamber, so that a reaction reagent in the reagent pipetting chamber is sprayed out through the reagent pipetting needle; the flux is not limited and can be flexibly changed according to requirements, the plate manufacturing speed is high, and the efficient requirement of large-scale experiments can be met.

This invention discloses a fully automated liquid-based cytology slide preparation and staining machine, comprising a frame, a turntable assembly, a lateral movement assembly, a lifting assembly, a push rod assembly, a solenoid valve assembly, a waste collection assembly, and a waste liquid collection assembly. The turntable assembly integrates sample bottles, pipette tips, slide clamps, and sedimentation baskets, enabling multi-channel sample loading. The lateral movement assembly and the lifting assembly work together to perform pipetting, sample addition, filter placement and removal, and staining operations. The push rod assembly drives the turntable assembly to perform centrifugal slide preparation. The solenoid valve assembly controls the actions of each actuator. The waste collection assembly and waste liquid collection assembly respectively achieve centralized treatment of waste and waste liquid. This invention integrates centrifugal slide preparation and automatic staining functions. The equipment has a compact layout and small footprint. It uses standard consumables and operates fully automatically. The multi-channel design improves slide preparation and staining efficiency, solving the technical problems of high cost and limited functionality of existing TCT equipment and cumbersome processes and high operational requirements of LCT equipment. It is suitable for liquid-based cytology testing scenarios in pathology departments.

A pipette tip, tip adapter, or tip cartridge includes a sealing tube with a negative or reverse taper to be inserted into one or more pipetting channels of a pipette; the sealing tube is characterized by a negative draft angle to cause the tip, adapter, or cartridge to be drawn against the dispensing head when mounted, sealed, and gripped. A tip rack assembly may comprise cartridges and pipette tips along with a pipette tip rack base and lid.