61 results about "Mechanical pipette" patented technology

The invention provides a pipettor leakage detection device, method and system. The device comprises a leak detection device, an integrated image capturing module and an environment sensor, imaging parameters are dynamically adjusted to carry out high-definition multispectral imaging on liquid drops suspended at the bottom of the suction head, and the sealing failure degree is analyzed and quantified in combination with liquid drop oscillation. The method comprises the following steps: distributing liquid by stages after liquid absorption, returning 90% of the liquid to a liquid storage device, and retaining 10% of the liquid to form liquid drops; and extracting liquid drop characteristics based on an airflow disturbance test and multispectral imaging, judging leakage if the liquid drop is missing or the area is smaller than a threshold value, triggering self-cleaning, generating a traceability report, and feeding back data to optimize a judgment threshold value. The system integrates a multi-channel pipetting head, a leakage detection device and a data processing center, images and pressure signals are subjected to cross validation through data fusion, and a motion control module is driven to execute a decision closed loop (pipetting is suspended during leakage, and micro leakage is remeasured). The full-time-history leakage detection of the multi-channel pipettor is realized, 384-channel detection is less than or equal to 8 seconds, and the high-throughput detection reliability is remarkably improved.

A computer-implemented control device for controlling an automated pipetting system. The control device is designed to control at least one actuator for moving a pipetting apparatus between receptacle devices for liquids that are to be pipetted. The control device is designed, so as, before the execution of multiple specified transfer steps by the pipetting apparatus and the actuator, to analyze the specified order of execution of these transfer steps and the liquid to be pipetted in these transfer steps and, after the analysis, to alter the order of execution of these transfer steps and / or to combine multiple instances of these transfer steps automatically. Additionally, an automated pipetting system has such a control device, and a method for controlling the automated pipetting system are provided.

A sample loading device and a gene sequencer, the sample loading device comprising: a fixed seat assembly, a gland assembly and a cap assembly, the fixed seat assembly having a fixed position for placing a slide frame loaded with a biochip; the gland assembly is rotatably connected to the fixed seat assembly, and the gland assembly is further snap-connected with the fixed seat assembly to fix the slide frame in the fixed position, and the gland assembly is provided with a positioning hole for installing a pipette head; the cap assembly is detachably arranged on the gland assembly and covers the positioning hole, and the cap assembly is used for pressing the pipette head in the positioning hole to provide a pushing force for the liquid in the pipette head. The sample loading device of the present application can realize the fixation of the slide frame by the gland assembly and the fixed seat assembly, and the cap assembly arranged on the gland assembly can provide a pushing force for the liquid in the pipette head, promote the flow of the internal liquid, and be beneficial to the automatic liquid passing of the biochip.

A multifunctional pipette set includes a pipette module, a heater module and a magnetic module. The pipette module includes one or more pipette heads. The heater module has a first joint part, and the heater module configured to removably connect to the pipette module by coupling the first joint part to at least one of the plurality of pipette heads. The magnetic module has a second joint part, and the magnetic module configured to removably connect to the pipette module by coupling the second joint part to at least one of the plurality of pipette heads. The multifunctional pipette set can be further applied in an automatic detection machine.

The invention discloses a multi-path automatic pipetting system for an automatic chemical synthesis experiment. The multi-path automatic pipetting system comprises a mechanical movement mechanism, a multi-path pipetting mechanism, a locking structure and a control system, the mechanical movement mechanism comprises X-axis and Y-axis mechanical arms which are vertically arranged, is driven by a stepping servo push rod motor, and is matched with an X / Y-axis photoelectric switch to calibrate displacement so as to construct a planar movement coordinate system; the multi-path pipetting mechanism is provided with a plurality of pipetting heads, and each channel is connected with a peristaltic pump through a connecting pipeline and is provided with a flow switch for monitoring the liquid flow in real time. The locking structure comprises a pipette fixing head, an inverted trapezoidal pressing ring and a pipette locking head, and the pipette penetrates through the pipette fixing head, the inverted trapezoidal pressing ring and the pipette locking head and is screwed into the pressing ring through threads to realize sealing; the control system is connected with the stepping motor, the peristaltic pump and the flow switch, calculates a movement track and pump parameters after receiving an instruction, synchronously controls the pipetting operation and processes a flow signal; according to the system, multi-channel accurate positioning, stable flow control and leakage prevention are achieved, and the matching precision, safety and automation efficiency of chemical synthesis experiments are remarkably improved.

This invention discloses a micro-volume liquid transfer system, a micro-volume liquid transfer method, and its application. The micro-volume liquid transfer system includes: a reservoir for storing the liquid to be transferred; a pipette tip made of a conductive material for picking up and transferring the liquid from the reservoir; a receiver made of a conductive material for receiving the liquid transferred by the pipette tip; a power supply electrically connected to the pipette tip for energizing the pipette tip to create a voltage difference between the pipette tip and the receiver; a controller electrically connected to the power supply for controlling the energization or de-energization of the pipette tip; and a drive assembly for driving the pipette tip to move, or for driving at least two of the movements of the reservoir, pipette tip, and receiver. The micro-volume liquid transfer system of this invention can transfer micro-volume liquids, is simple, fast, efficient, reliable, and accurate.

The utility model discloses a multi-caliber pipetting head. The multi-caliber pipetting head comprises a pipetting head body, the pipetting head body comprises a connecting sleeve, a connecting pipe, a pipette and a suction head, a sealing lantern ring is installed at the end of the pipette, the sealing lantern ring is made of an elastic silica gel material, a plurality of sets of cavities with different calibers are formed in the connecting pipe, and the connecting pipe is connected with the suction head. The pipettes can be matched with the sealing lantern rings installed at the ends to be installed in the multiple sets of cavities with different calibers of the connecting pipe, and through the arrangement of the connecting pipe, the pipettes and the suction heads, when various kinds of liquid with different properties need to be treated in a laboratory, the cavities with different calibers are formed in the connecting pipe to be matched with the pipettes for use, so that the liquid with different properties can be treated conveniently. The pipette can adapt to liquids with different viscosities and surface tensions through the design of the cavity and the use of the sealing ring, and meanwhile, residues of the liquids in the pipetting process can be reduced, so that the pipetting accuracy is improved.

A pipetting head 100 comprising a pipette body mounting assembly 120 with an array of pipette body mounts, and a moveable pipette guide assembly 180 having a guide plate 182 comprising a plurality of

The invention relates to a pipetting plate making system. The pipetting plate making system comprises a pipetting head module, pipetting device cleaning equipment and a pipetting arm, the pipetting head module comprises a pipetting mechanism, a liquid suction and spray driving mechanism and a pipetting head quick-changing device, the pipetting mechanism is provided with a suction head connecting part, and the pipetting mechanism is detachably connected with the liquid suction and spray driving mechanism through the pipetting head quick-changing device; the liquid sucking and spraying driving mechanism drives the liquid transferring mechanism to provide positive pressure or negative pressure for the suction head connecting part; the pipetting device cleaning equipment comprises a plurality of mutually independent cleaning channels, the water inlet mechanism is connected with the cleaning channels to input cleaning liquid, the first drainage mechanism is connected with the cleaning channels to discharge the cleaning liquid, and at least one pipetting suction head extends into each cleaning channel; the pipetting arm is in driving connection with the pipetting head module and is used for driving the pipetting head module to move to a preset working position; wherein the preset working positions comprise a sample plate liquid absorption position, a reaction plate liquid spraying position and a cleaning position. Multi-flux flexible use can be achieved, efficiency is high, and cross contamination is not prone to being generated.

A method of measuring the alignment of one or more pipetting tips in an automated pipetting system where the one or more pipetting tips are mounted on one or more adapters of a pipetting head approximately perpendicular to the pipetting head mounting surface is disclosed. The orifices at the end of the one or more pipetting tips are mapped with an image capture device having a sensor placed in face and distant of the orifices. The method sends the acquired data from mapping the orifices of the one or more pipetting tips to the data processor, generating an image of the orifices of the one or more pipetting tips, determining the center positions of orifices, and delivering alignment information for the one or more pipetting tips.

A pipetting system is disclosed that includes a pipette head including a multichannel air displacement system for aspirating and dispensing liquids, a pipetting system base that includes a linear guide system along which the pipette head may be moved vertically with respect to the pipetting system base, and counterbalance means for counterbalancing at least a portion of a weight of the pipette head.

The utility model relates to the technical field of pipetting equipment, in particular to mechanical arm-based pipetting equipment which comprises a base, an operation table is arranged at the top of the base, two mechanical arms are fixedly mounted at the top of the operation table, pipetting heads are fixedly mounted at the bottoms of the mechanical arms, and cleaning and disinfecting mechanisms are arranged on the left side and the right side of the operation table; the cleaning and disinfecting mechanism comprises a banister brush used for friction disinfection, a movable damping mechanism is arranged at the bottom of the operation table, a mechanical arm is started to drive a pipetting head to be inserted into a cleaning box, so that the pipetting head is immersed into alcohol, then a motor is started to drive a rotating cylinder to rotate, and the banister brush scrubs the pipetting head; therefore, during immersion, gaps of the pipetting head are brushed and disinfected, stubborn bacteria and viruses are prevented from remaining in the gaps, cross contamination is prevented, the accuracy and reliability of experimental results are prevented from being influenced, the disinfection effect is effectively improved, and the success of experiments is ensured.

The present invention provides a mechanical positioning multichannel pipettor, and relates to the field of pipettors, the mechanical positioning multichannel pipettor comprises a main body, a plurality of pipetting channels arranged on the main body, and pipetting heads arranged at one end of the main body and corresponding to the pipetting channels, and further comprises: an adjusting mechanism arranged in the main body, the adjusting mechanism comprises an adjusting slide block moving along the length direction of the main body; the positioning assembly comprises a positioning block, a guide sliding rail and a locking piece. The adjusting sliding block is arranged on one side of the positioning block, the guide sliding rail is fixedly arranged in the main body, and the positioning block is slidably arranged on the guide sliding rail; the locking piece is movably arranged on the main body, and the locking piece is provided with a locking position selectively matched with the positioning block and a releasing position separated from the positioning block; wherein the adjusting slide block is in transmission connection with the pipetting channel through the connecting assembly. The device has the advantages of being accurate in adjustment, reliable in locking, visual in operation and durable in structure. The accuracy and stability of spacing adjustment are ensured, and the use convenience is improved through visual indication and operation design.

A pipette with a filtering and separating device comprises a pipette body and a pipette head, the pipette head is movably connected to the lower portion of the pipette body, a filtering and separating mechanism is arranged in the pipette head, and the filtering and separating mechanism comprises a plurality of filtering membranes with different pore diameters; the pipette body comprises a liquid storage cavity and a pressing suction head; according to the pipette with the separation device, separation and filtration of macromolecules and micromolecules are realized in the pipetting process, so that additional steps of centrifugation, filtration and the like are reduced, the experimental process is greatly simplified, and time and energy are saved; the filtering mechanism adopts a replaceable design, and a user can replace and clean the filtering mechanism according to needs, so that the risk of cross contamination is avoided, and the purity of a sample and the accuracy of an experimental result are ensured; the filtering module and the pipetting head are designed into detachable and replaceable structures, so that the cleaning and maintenance are convenient, the service life of the pipetting gun is prolonged, and the maintenance difficulty and cost are reduced.

The application discloses a kind of pipette head intelligent production line system detection module and detection method, belong to pipette head detection technical field, including including frame, handling unit and detection unit;The number of handling unit is 2, respectively set at the two ends of frame;Detection unit includes the detection slide table of bearing pipette head and the visual detection device for checking the defect of pipette head, visual detection device is fixedly connected on frame by fixing frame;Detection slide table is slidably arranged on frame;Detection slide table drives pipette head to pass through visual detection device.The application can replace artificial operation, avoids the pollution in the placement process of pipette head, and the placement precision is high, avoids appearing inclination, and the placement and removal of pipette head are all automatic operation, meanwhile, PLC controller can judge good product and non-good product in time according to the video image of detection device, and accurate position is given, and detection efficiency is high.

A pipette for use with a pipetting head of a liquid dispensing apparatus, the pipette comprising a pipette tip 1100 having a distal end 1102 with dispensing aperture 1108 and a proximal end 1101 with

A laboratory automation apparatus with a liquid volume measurement functionality comprising a working table, a pipettor comprising a pipetting head with an electrode providing a capacitive sensor with a reference electrode. A robotic arm is configured to move the pipetting head above the working table. A processor is operatively coupled to the robotic arm, to the pipettor and to the electrode by an electronic circuit. A capillary is located on the working table having an opening for receiving a target amount of liquid from the pipettor to form an air-liquid meniscus in the capillary. The robotic arm is configured to hover the electrode over the capillary to detect a change in capacitance related to the position of the meniscus, and the processor is configured to calculate the transferred amount of liquid from the position of the meniscus in the capillary.

The current invention involves a method of isolating a pathogen from a food sample using an automated pipetting system to remove supernatant from centrifuge tubes down to a calibrated volume. The automated pipetting system includes an automated pipetting system with the capacity to determine the calibrated volume to prevent disturbing a biological mass at the bottom of the centrifuge tubes.

The invention relates to a pipette convenient for withdrawing a pipette head and a driving device, and relates to the technical field of liquid transfer. Comprising a shell, a pipetting head containing a pipetting shell and a pipetting tube is installed on the shell, a pipetting cavity is formed in the pipetting tube, a gun head is sleeved with an end clamping part, a gun head withdrawing assembly, a push handle and a driving piece are further arranged, and a gun withdrawing tube can be pushed out of the gun head when the push handle moves downwards; the push rod is provided with a movable groove, a movable handle and one-way limiting teeth, and is matched with a one-way limiting groove in the transfer pipette; a spring cavity and a reset spring are also arranged in the pipette; a gun withdrawing spring is arranged outside the gun withdrawing pipe; the shell is provided with a sealing clamping groove and a sealing plug; the push rod is sleeved with a limiting ring; sliding rails and clamping assemblies are arranged on the two sides of the shell, each clamping assembly comprises a sliding block, a lead column, a clamping block, a compression spring and the like, and each sliding block is provided with a guide groove, an abutting plate and an adjusting insertion hole. The technical effects of conveniently withdrawing the pipette head, stably fixing the pipette head and accurately operating and controlling the pipette head are achieved.

The application relates to the technical field of automatic pipetting, in particular to an automatic pipetting system which comprises a sleeve, the bottom end of the sleeve is integrally formed with a plug pipe, a suction pipe is inserted into the plug pipe, characterized in that: a pressure control pipe is arranged in the sleeve and communicated with the plug pipe, a piston which moves along the axial direction of the pressure control pipe is slidably embedded in the pressure control pipe, the position of the piston is adjusted and controlled through a threaded transmission structure, the top end of the sleeve is fixedly connected with a cover plate, and a socket which is communicated with and controlled by the outside is arranged on the top of the cover plate. According to the scheme, the pressure control pipe which is communicated with the plug pipe is arranged in the sleeve, a piston which is driven through a threaded structure is slidably embedded in the pressure control pipe, the position of the piston is conveniently controllable, in addition, the socket and the external control structure are docked on the outside of the sleeve, and the pipetting structure is conveniently controlled.

This utility model discloses a novel pipette, relating to the field of laboratory instruments. The technical solution includes a pipette body and a pipette tip detachably connected to the pipette body. A connecting tube is fixedly installed at the lower end of the pipette body, and the lower end of the connecting tube is tapered. The pipette tip is detachably connected to the tapered portion of the connecting tube. A groove is formed on the tapered portion of the connecting tube, and a locking tongue, shaped like a right-angled trapezoid, is slidably installed within the groove. The smaller bottom surface of the locking tongue faces the lower end of the connecting tube. A sliding hole is formed on the side wall of the connecting tube, with the axis of the sliding hole parallel to the axis of the connecting tube. A pressing rod is slidably installed inside the vertical tube, and the upper end of the pressing rod extends to the outside of the pipette body and is fixed to the release button of the pipette body. The beneficial effect of this utility model is that it makes the connection between the pipette and the pipette tip more stable and tight, thereby improving the fixation performance of the pipette tip and avoiding the problem of easy detachment.

The invention discloses a pipettor with a visual suck-back prevention warning structure, and relates to the technical field of pipettors, the pipettor comprises a shell and a pipettor main body, the bottom end of the shell is connected with the pipettor main body, and the bottom end of the pipettor main body is fixedly provided with a pipetting head. A blending mechanism is arranged in the shell and is driven by a left motor and a right motor, the outer sides of output shafts of the left motor and the right motor are connected with a first bevel gear and a half-tooth bevel gear respectively, and the half-tooth bevel gear is larger than the first bevel gear, that is, the half-tooth bevel gear can be in meshed connection with a second bevel gear and a third bevel gear; the first bevel gear can only be in meshed connection with the second bevel gear, so that two operation modes of unidirectional rotation and reciprocating rotation can be realized, the pipettor has more functions, namely, various different experiment operations can be completed on one pipettor, other instruments do not need to be replaced, and the experiment cost and the occupied space of the equipment are reduced.

An automated pipetting system includes a pipettor. The pipettor includes a pipetting channel, a first plunger mechanism operable to change a pressure in the pipetting channel to aspirate or dispense a liquid, and a second plunger mechanism operable to change the pressure in the pipetting channel to aspirate or dispense the liquid.

The invention relates to a pipetting system comprising: - a support (20) comprising a plurality of pipetting cones (12), said support (20) being arranged on a rectangular matrix of rows and columns; - a pipetting head (1) comprising a housing (10) accommodating a plurality of pipetting channels arranged on a rectangular matrix of rows and columns, each of said pipetting channels being provided with a tip (11) intended to cooperate with one of said pipetting cones (12) by fitting so as to receive or dispense liquid, said pipetting head (1) being movable in a predefined range of movement between a raised position in which said tips (11) are at a distance from said pipetting cones (12) and an engaged position in which the pipetting cones (12) are fitted onto said tips (11);- an actuating lever (4) configured to drive said pipetting head (1) in vertical translation between said raised position and said engaged position in response to a force applied on said actuating lever (4), said actuating lever (4) being rotationally movable between at least one rest position and a pivoted position so as to move said pipetting head (1) from said raised position to said engaged position, characterized in that said pipetting system further comprises means for controlling an axial fitting force along said vertical axis (V) of said pipetting cones (12) onto said tips (11) generated by said rotation of said actuating lever (4) between said rest position and said pivoted position.;

The utility model relates to the technical field of experimental instruments, in particular to a four-channel variable-pitch pipetting module, which comprises a four-channel variable-pitch assembly, four groups of lifting assemblies and four groups of pipetting assemblies, the four-channel variable-pitch assembly is connected with the four groups of lifting assemblies, and the four groups of lifting assemblies are respectively connected with the four groups of pipetting assemblies. According to the four-channel variable-pitch pipetting module, through cooperation of the pitch changing assembly, the lifting assembly and the pipetting assembly, the four sets of pipetting heads can be driven to achieve lifting and pitch changing at the same time, meanwhile, the pipetting heads are of an adjustable structure, the positions of the pipetting heads can be flexibly adjusted, and therefore the movement range of the pipetting heads is greatly widened, and the application range of the four-channel variable-pitch pipetting module is widened.

The utility model relates to the technical field of biological experiment detection equipment, in particular to a supporting structure for loading a pipette head and a pipette head assembly. According to the supporting structure for loading the pipette head, the pipette head is arranged on a supporting plate, and the supporting structure comprises a supporting main body, an accommodating cavity and a loading window which are communicated with each other are formed in the supporting main body; the supporting piece is arranged in the loading window and connected with the supporting main body, and the supporting piece is arranged to be capable of supporting the supporting plate together in the height direction in cooperation with the supporting main body after the pipetting head is loaded into the containing cavity through the loading window. According to the utility model, the supporting structure is optimally designed, so that the supported area of the supporting plate in the loading process of the pipettor is increased, and the heights of a plurality of pipetting heads are uniform when the pipettor is loaded, so as to avoid liquid suction and drainage errors in the pipetting process.

The invention relates to a high throughput pipetting plate making system. The high-throughput pipetting plate making system comprises a pipetting head module, a pipetting device cleaning device, a pipetting arm and a stacking device. Wherein the pipetting head module comprises a pipetting mechanism, a liquid sucking and spraying driving mechanism and pipetting head quick-changing equipment, and the pipetting mechanism is detachably connected with the liquid sucking and spraying driving mechanism through the pipetting head quick-changing equipment; the pipetting device cleaning equipment comprises a plurality of mutually independent cleaning channels, and at least one pipetting suction head extends into each cleaning channel; the pipetting arm drives the pipetting head module to move to a preset working position; wherein the preset working positions comprise a sample plate liquid absorption position, a reaction plate liquid spraying position and a cleaning position; the stacking device is used for storing consumables and carrying out consumable interaction on the consumables and the pipette head module. The system can be flexibly used in a multi-flux manner, is high in efficiency, is not liable to generate cross contamination, automatically and interactively takes and places consumables, improves the consumable feeding efficiency, improves the plate making efficiency, and guarantees the pipetting precision.