Provided is a full-automatic machine for sewing trouser buttons. The full-automatic machine for sewing the trouser buttons comprises a base (1), wherein a stand column (3) is fixed to the base (1), a machine head (2) is installed at the upper end of the stand column (3), a strike driving device is installed in the machine head (2), a strike rod (4) is perpendicularly fixed to the lower end, in the axis direction, of the bottom of the strike driving device, a rotary disk (6) is installed at the position, arranged on the outer side of the strike rod (4), of the bottom of the strike driving device through a rotary shaft (5), more than one rotary die head (7) is fixed to the circumference of the bottom surface of the rotary disk (6), a rotation driving device is installed on the rotary disk (6), and a button conveying slide way (11) is arranged between the stand column (3) and a button sewing working position arranged on the base (1). The full-automatic machine for sewing the trouser buttons is compact in structure, button placement, button locating and button sewing are automatically accomplished, labor intensity of operators is greatly reduced, processing efficiency is high, safety performance is good, the buttons are sewed accurately and firmly, and large-scale button sewing is facilitated.