Cell crusher

By designing a cell crusher that includes an automatic fixation component, the problem of vibration caused by vial shift caused by cell crushing is solved by shaking the cell crusher when shaking cells, improving the stability of cell crushing and adapting to vials of different heights.

CN222499148UActive Publication Date: 2025-02-18武汉百泰康基因技术有限公司
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Patent Information

Application Number
CN202420535308.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-19
Publication Date
2025-02-18
Estimated Expiration
2034-03-19

AI Technical Summary

Technical Problem

Existing cell crushers will produce vibrations when crushing cells, causing sample vials to shake and shift, reducing the stability of cell crushing.

Method used

A cell crusher including a crushing cabinet, a placement assembly and a fixing assembly was designed. The placement components include mounting plates, anti-slip base plates, sliding voids and return springs. The fixing components can automatically fix the sample bottles through components such as sliding blocks, clamping blocks and rubber blocks to reduce vibrations.

Benefits of technology

By automatically fixing the vial, the vibration caused by crushing cells is reduced, the vial offset is avoided, the stability of cell crushing is improved, and the vial can be adapted to sample vials of different heights.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a cell disintegrator which comprises a disintegrator cabinet, and the disintegrator cabinet comprises a disintegrator cabinet for disintegrating cells and a driving cabinet electrically connected with the disintegrator cabinet; when a worker needs to crush cells, the sealed cabinet door is opened firstly, then the fixing assembly at the top end of the placement assembly is adjusted according to a sample bottle containing the cells, the sliding block is pulled in the first direction, and the sliding blocks at the two ends of the sliding block can always keep sliding in the sliding grooves through torsion springs in the sliding cavities; when the amplitude rod slides to a certain distance, the sample bottle is placed in the middle of the multiple sets of fixing assemblies, the fixing assemblies are loosened at the moment, the fixing assemblies automatically approach the sample bottle due to the stress of reset springs until the fixing assemblies abut against the sample bottle and are fixed, and the sample bottle can be fixed under the amplitude rod through the fixing assemblies. The condition of sample bottle deviation caused by vibration generated by cell crushing is reduced, and the stability of cell crushing is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of cell crushing equipment, in particular to a cell crusher. Background Art

[0002] Cell crushers are used to break cells in biological samples into fine particles or liquids. These devices are often used in biology, molecular biology and biochemistry research to extract proteins, nucleic acids or other cellular components in cells.

[0003] The cell crusher can quickly and thoroughly crush cells, saving researchers time and energy. However, the cell crusher will generate vibrations when crushing cells, which will cause the sample bottles containing the cells to shake and cause displacement, but this reduces the stability of the cell crusher in crushing cells. Utility Model Content

[0004] The purpose of the utility model is to provide a cell crusher to solve the problem that the existing cell crusher can crush cells quickly and thoroughly, saving researchers' time and energy, but the cell crusher will generate vibrations when crushing cells, which will shake the sample bottle containing the cells and cause displacement, but this reduces the stability of the cell crusher in crushing cells.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a cell crusher, comprising a crushing cabinet, the crushing cabinet comprising a crushing cabinet for crushing cells and a driving cabinet electrically connected to the crushing cabinet, one end of the crushing cabinet is rotatably connected to a sealing cabinet door for sealing, a placement component for placing sample tubes is arranged inside the crushing cabinet, the placement component comprises a mounting plate installed inside the crushing cabinet and a non-slip bottom plate fixedly installed on the top of the mounting plate, sliding grooves that are slidably connected to the fixed component are evenly opened on the top of the non-slip bottom plate, the fixed component comprises a sliding block that slides with the sliding groove and a clamping block fixedly arranged on the top of the sliding block, and a rubber block that increases the friction with the sample tube is fixedly installed on one end of the clamping block.

[0006] As a further solution of the utility model: a sliding groove sliding with the slider is opened inside the sliding slot, and the sliding groove is symmetrically opened inside the sliding slot, and the sliders are symmetrically arranged at both ends of the sliding block.

[0007] As a further solution of the utility model: a return spring is arranged inside the sliding slot to increase the fixing force of the fixing component.

[0008] As a further solution of the utility model: sliding cavities for sliding with the slider are symmetrically opened at both ends of the sliding block, and a torsion spring for increasing the distance between the slider and the sliding groove is fixedly installed inside the sliding cavity.

[0009] As a further solution of the utility model: a clamping extension plate is slidably connected to the top of the clamping block, one end of the clamping extension plate is provided with a limit groove which is fixed with the limit rod, and the limit grooves are evenly and symmetrically arranged at both ends of the clamping block, and the limit grooves are also symmetrically arranged at both ends of the clamping block.

[0010] As a further solution of the utility model: a connecting rod is inserted at the top of the crushing cabinet and located directly above the placement component, and the connecting rod is electrically connected to the driving cabinet, and the connecting rod passes through the crushing cabinet and is connected to an amplitude rod.

[0011] As a further solution of the utility model: an observation window for observing cell crushing is arranged at one end of the sealed cabinet door.

[0012] Compared with the prior art, the beneficial effects of the utility model are:

[0013] 1. When the staff of the utility model needs to crush the cells, they first open the sealed cabinet door, then adjust the fixing assembly at the top of the placing assembly according to the sample bottle containing the cells, pull the sliding block forward, and the sliders at both ends of the sliding block can always keep the sliders sliding in the slide groove through the torsion springs inside the sliding cavity. When sliding to a certain distance, the sample bottle is placed in the middle of the multiple groups of fixing assemblies. At this time, the fixing assembly is released. The fixing assembly automatically approaches the sample bottle due to the stress of the reset spring until it abuts against and is fixed thereto. The sample bottle can be fixed directly under the amplitude rod through the fixing assembly, thereby reducing the deviation of the sample bottle caused by the vibration generated by the crushed cells and increasing the stability of the cell crushing.

[0014] 2. At the same time, the rubber block at one end of the clamping block can increase the friction between the clamping block and the sample bottle, thereby increasing the stability of the fixation. When it is necessary to fix sample bottles of different heights, the limit rod is removed from the limit grooves at both ends of the clamping extension plate and the clamping block, and then the clamping extension plate is pulled to the required height, and then the limit rod is inserted back in the opposite direction to complete the fixation. The clamping extension plate can be used to conveniently fix sample bottles of different heights, further increasing the functionality of the fixing assembly. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0016] Figure 2 This is a schematic diagram of the expanded structure of the pulverizing cabinet of the utility model;

[0017] Figure 3 It is a structural schematic diagram of the placement component of the utility model;

[0018] Figure 4 This utility model Figure 3A schematic diagram of the enlarged structure at A in the middle;

[0019] Figure 5 It is a schematic diagram of the internal structure of the sliding block of the utility model;

[0020] Figure 6 It is a partial three-dimensional structural schematic diagram of the clamping block of the utility model.

[0021] In the figure: 1. Crusher cabinet; 11. Crusher cabinet; 12. Drive cabinet; 13. Sealed cabinet door; 14. Observation window; 15. Connecting rod; 16. Amplitude rod; 2. Placement component; 21. Mounting plate; 22. Anti-skid bottom plate; 23. Sliding slot; 24. Sliding slot; 25. Reset spring; 3. Fixing component; 31. Sliding block; 32. Anti-skid bottom plate; 33. Torsion spring; 34. Sliding block; 35. Clamping block; 36. Rubber block; 37. Clamping extension plate; 38. Limiting slot; 39. Limiting rod. DETAILED DESCRIPTION

[0022] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0023] In the description of the present utility model, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, which are only for the convenience of describing the present utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific position, be constructed and operated in a specific position, and therefore cannot be understood as a limitation of the present utility model. In addition, the terms "first", "second", and "third" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance. In the description of the present utility model, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", and "set" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected, or indirectly connected through an intermediate medium, or it can be the internal connection of two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances. The following is an explanation of the embodiments of the present utility model based on the overall structure of the present utility model.

[0024] Reference Figures 1 to 6In an embodiment of the utility model, a cell crusher includes a crushing cabinet 1, which includes a crushing cabinet 11 for crushing cells and a driving cabinet 12 electrically connected to the crushing cabinet 11, one end of the crushing cabinet 11 is rotatably connected to a sealing cabinet door 13 for sealing, and a placement component 2 for placing a sample tube is arranged inside the crushing cabinet 11, the placement component 2 includes a mounting plate 21 installed inside the crushing cabinet 11 and a non-slip bottom plate 22 fixedly installed on the top of the mounting plate 21, and the top of the non-slip bottom plate 22 is evenly provided with sliding grooves 23 slidably connected to the fixed component 3, the fixed component 3 includes a sliding block 31 sliding with the sliding groove 23 and a clamping block 35 fixedly arranged on the top of the sliding block 31, and a rubber block 36 for increasing friction with the sample tube is fixedly installed on one end of the clamping block 35, and an observation window 14 for conveniently observing cell crushing is arranged at one end of the sealing cabinet door 13.

[0025] Reference Figures 3 to 6 A sliding groove 24 is provided inside the sliding groove 23 for sliding with the slider 34, and the sliding groove 24 is symmetrically provided inside the sliding groove 23. The sliders 34 are symmetrically arranged at both ends of the sliding block 31. A return spring 25 is provided inside the sliding groove 23 to increase the fixing force of the fixing component 3.

[0026] Reference Figures 4 to 6 The sliding block 31 has symmetrical sliding cavities 32 at both ends thereof for sliding with the slider 34, and a torsion spring 33 for increasing the distance between the slider 34 and the slide groove 24 is fixedly installed inside the sliding cavity 32. The top of the clamping block 35 is slidably connected to a clamping extension plate 37, and one end of the clamping extension plate 37 is provided with a limiting groove 38 fixed with a limiting rod 39, and the limiting grooves 38 are evenly and symmetrically provided at both ends of the clamping block 35, and the limiting grooves 38 are also symmetrically provided at both ends of the clamping block 35.

[0027] Reference Figure 1 and Figure 2 A connecting rod 15 is inserted at the top of the crushing cabinet 11 and located directly above the placement component 2, and the connecting rod 15 is electrically connected to the driving cabinet 12. The connecting rod 15 passes through the crushing cabinet 11 and is connected to an amplitude rod 16.

[0028] The working principle of the utility model is as follows: when the staff needs to crush the cells, first open the sealed cabinet door 13, then adjust the fixing component 3 at the top of the placing component 2 according to the sample bottle containing the cells, pull the sliding block 31 in the first direction, and the sliders 34 at both ends of the sliding block 31 can always keep the sliders 34 sliding in the sliding groove 24 through the torsion springs 33 inside the sliding cavity 32. When sliding to a certain distance, the sample bottle is placed in the middle of the multiple groups of fixing components 3. At this time, the fixing component 3 is released. The fixing component 3 automatically approaches the sample bottle due to the stress of the reset spring 25 until it abuts against and is fixed thereto. The sample bottle can be fixed by the fixing component 3 Directly below the amplitude rod 16, the deviation of the sample bottle caused by the vibration generated by the cell crushing is reduced, and the stability of the cell crushing is increased. At the same time, the rubber block 36 at one end of the clamping block 35 can increase the friction between the clamping block 35 and the sample bottle, thereby increasing the stability of the fixation. When it is necessary to fix sample bottles of different heights, the limit rod 39 is taken out from the limit grooves 38 at both ends of the clamping extension plate 37 and the clamping block 35, and then the clamping extension plate 37 is pulled to the required height, and then the limit rod 39 is inserted back in the opposite direction to complete the fixation. The clamping extension plate 37 can be used to conveniently fix sample bottles of different heights, further increasing the functionality of the fixing component 3.

[0029] What is described above is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A cell crusher, characterized in that: The invention comprises a crushing cabinet (1), wherein the crushing cabinet (1) comprises a crushing cabinet (11) for crushing cells and a driving cabinet (12) electrically connected to the crushing cabinet (11); one end of the crushing cabinet (11) is rotatably connected to a sealing cabinet door (13) for sealing; a placement component (2) for placing a sample tube is arranged inside the crushing cabinet (11); the placement component (2) comprises a mounting plate (21) mounted inside the crushing cabinet (11) and an anti-skid bottom plate (22) fixedly mounted on the top of the mounting plate (21); the top of the anti-skid bottom plate (22) is evenly provided with The fixing component (3) is slidably connected to the sliding slot (23), the fixing component (3) comprises a sliding block (31) sliding with the sliding slot (23) and a clamping block (35) fixedly arranged at the top of the sliding block (31), and a rubber block (36) for increasing the friction with the sample tube is fixedly installed at one end of the clamping block (35), a connecting rod (15) is inserted at the top of the crushing cabinet (11) and located directly above the placement component (2), and the connecting rod (15) is electrically connected to the driving cabinet (12), and the connecting rod (15) passes through the crushing cabinet (11) and is connected to an amplitude rod (16).

2. A cell crusher according to claim 1, characterized in that: A sliding groove (24) for sliding with a sliding block (34) is provided inside the sliding groove (23), and the sliding groove (24) is symmetrically provided inside the sliding groove (23), and the sliding blocks (34) are symmetrically arranged at two ends of the sliding block (31).

3. A cell crusher according to claim 1, characterized in that: A return spring (25) for increasing the fixing force of the fixing component (3) is arranged inside the sliding slot (23).

4. A cell crusher according to claim 1, characterized in that: The two ends of the sliding block (31) are symmetrically provided with sliding cavities (32) for sliding with the sliding block (34), and a torsion spring (33) for increasing the distance between the sliding block (34) and the sliding groove (24) is fixedly installed inside the sliding cavity (32).

5. A cell crusher according to claim 1, characterized in that: The top end of the clamping block (35) is slidably connected to a clamping extension plate (37), one end of the clamping extension plate (37) is provided with a limiting groove (38) which is fixed to a limiting rod (39), and the limiting groove (38) is evenly and symmetrically opened at both ends of the clamping block (35), and the limiting groove (38) is also symmetrically opened at both ends of the clamping block (35).

6. A cell crusher according to claim 1, characterized in that: An observation window (14) for conveniently observing cell pulverization is provided at one end of the sealed cabinet door (13).