Stably-mounted bioreactor for biopharmacy

Abstract

The utility model discloses a bio-pharmaceutical bioreactor of stable installation, including base, support rod and bioreactor, support rod is installed on the upper end of base, the bioreactor is installed on the upper end of support rod, the bioreactor is provided with the support subassembly for the bio-pharmaceutical bioreactor of stable support, the support subassembly is installed on the base, and the support subassembly is installed on the base. A discharging assembly is arranged at the bottom of the bioreactor and enables the bioreactor to conveniently and smoothly discharge materials, and relates to the technical field of bioreactors, the discharging assembly is arranged at the bottom end of the bioreactor, when a discharging pipe discharges materials, sediment at the bottom of the bioreactor is stirred through a first scraping rod, and discharging blockage of the bioreactor is avoided; the telescopic rod and the guide rod are arranged at the upper end of the bioreactor, the telescopic rod drives height adjustment of the top plate, and the guide rod guides lifting of the top plate, so that the top plate at the upper end of the bioreactor is convenient to open.

Description

Technical Field

[0001] The utility model relates to the field of bioreactors, in particular to a stably installed bioreactor for biopharmaceuticals. Background Art

[0002] A bioreactor refers to a reaction system that uses naturally existing microorganisms or microorganisms with special degradation capabilities to inoculate into a liquid or solid phase. A bioreactor is a device system that uses the biological functions of enzymes or organisms to perform biochemical reactions in vitro. It is a biological function simulator, such as a fermenter, immobilized enzyme or immobilized cell reactor, etc. However, the precipitation in the bioreactor will accumulate at the bottom, and the liquid in the bioreactor is prone to clogging when discharged, resulting in unsmooth discharge of the bioreactor. The upper end of the bioreactor is generally fixed by bolts, which is not easy to open;

[0003] Therefore, it is necessary to invent a bioreactor for biopharmaceuticals that can be stably installed. Utility Model Content

[0004] The purpose of the utility model is to provide a stably installed bioreactor for biopharmaceuticals to solve the problems raised in the above background technology.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] A stably installed biopharmaceutical bioreactor comprises a base, a support rod and a bioreactor, wherein the support rod is installed at the upper end of the base, and the bioreactor is installed at the upper end of the support rod. A support assembly for stably supporting the biopharmaceutical bioreactor is arranged on the bioreactor, and a discharge assembly is arranged at the bottom of the bioreactor, wherein the discharge assembly comprises a motor seat and a discharge pipe, wherein the motor seat is installed on the base, and a discharge pipe is installed between the motor seat and the bioreactor, and a motor B is installed inside the motor seat, and a rotating rod is rotatably installed inside the discharge pipe, a scraper rod 1 is installed at the upper end of the rotating rod, and a scraper rod 2 is installed on the side wall of the rotating rod, and a shunt pipe 1 and a shunt pipe 2 are respectively installed at the side ends of the discharge pipe, and valves are installed on the shunt pipe 1 and the shunt pipe 2, and pipe plugs are threadedly installed at the ends of the shunt pipe 1 and the shunt pipe 2, and the support assembly comprises a telescopic rod, a top plate and a bearing, wherein the telescopic rod is installed at the upper end of the bioreactor, a bearing is installed at the output end of the telescopic rod, and a top plate is installed on the outer wall of the bearing, and the discharge assembly makes it easy for the bioreactor to discharge smoothly.

[0007] In a preferred embodiment of the present invention, a sealing ring and a guide rod are respectively installed at the lower end of the top plate, the guide rod is inserted into the upper end of the bioreactor, and a fixing block is installed at the side end of the base.

[0008] In a preferred embodiment of the present invention, a support tube and a feed tube are respectively installed on the upper end of the top plate, a motor A is installed on the upper end of the support tube, and an output end of the motor A is connected to a stirring rod.

[0009] Additional aspects and advantages of the present invention will be given in part in the following description, and in part will become apparent from the following description, or will be learned through the practice of the present invention.

[0010] Beneficial effects:

[0011] By arranging a discharge assembly at the bottom of the bioreactor, the discharge pipe stirs the sediment at the bottom of the bioreactor through a scraper rod when discharging, thereby avoiding blockage of the bioreactor discharge;

[0012] By arranging a telescopic rod and a guide rod on the upper end of the bioreactor, the telescopic rod drives the top plate to adjust its height, and the guide rod guides the top plate to rise and fall, so that the top plate on the upper end of the bioreactor is easy to open. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 Schematic diagram of a bioreactor for biopharmaceuticals in a stable installation Figure 1 ;

[0014] Figure 2 Schematic diagram of a bioreactor for biopharmaceuticals in a stable installation Figure 2 ;

[0015] Figure 3 A schematic diagram of a discharge assembly in a bioreactor for biopharmaceuticals that is stably installed;

[0016] Figure 4 Schematic diagram of a stably mounted rotating rod in a bioreactor for biopharmaceuticals.

[0017] In the figure: base 1, support rod 11, support tube 12, motor A13, feed tube 14, bioreactor 15, stirring rod 16, support assembly 2, telescopic rod 21, top plate 22, sealing ring 23, guide rod 24, bearing 25, fixing block 26, discharge assembly 3, motor seat 31, motor B32, discharge tube 33, diverter tube 1 34, diverter tube 2 341, pipe plug 342, valve 35, rotating rod 36, scraper rod 1 37, scraper rod 2 38. DETAILED DESCRIPTION

[0018] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention.

[0019] Example 1: Figure 1-Figure 4 ,

[0020] The bioreactor 15 comprises a base 1, a support rod 11 and a bioreactor 15. The support rod 11 is mounted on the upper end of the base 1, and the bioreactor 15 is mounted on the upper end of the support rod 11. The bioreactor 15 is provided with a support assembly 2 for stably supporting the bioreactor for biopharmaceuticals. The bottom of the bioreactor 15 is provided with a discharge assembly 3, and the discharge assembly 3 enables the bioreactor 15 to discharge smoothly.

[0021] The discharge assembly 3 includes a motor seat 31 and a discharge pipe 33. The motor seat 31 is installed on the base 1. The motor seat 31 is used to support the installation of the motor B32. The discharge pipe 33 is installed between the motor seat 31 and the bioreactor 15. The bioreactor 15 is discharged through the discharge pipe 33. The motor B32 is installed inside the motor seat 31. The motor B32 is used to drive the rotating rod 36 to rotate. The rotating rod 36 is installed inside the discharge pipe 33. The rotating rod 36 is used to drive the scraper rod 1 37 and the scraper rod 2 38 to rotate. The scraper rod 1 37 is installed on the upper end of the rotating rod 36. The scraper rod 1 37 is used to stir the sediment at the bottom of the bioreactor 15. To avoid clogging, a scraper rod 38 is installed on the side wall of the rotating rod 36. The scraper rod 38 is used to stir the inside of the discharge pipe 33 to avoid clogging. The side ends of the discharge pipe 33 are respectively installed with a diverter pipe 1 34 and a diverter pipe 2 341. The diverter pipe 1 34 and the diverter pipe 2 341 are used to divert and discharge the liquid in the bioreactor 15. Valves 35 are installed on the diverter pipe 1 34 and the diverter pipe 2 341. The valve 35 is used to control the opening of the diverter pipe 1 34 and the diverter pipe 2 341. The ends of the diverter pipe 1 34 and the diverter pipe 2 341 are threadedly installed with pipe plugs 342. The pipe plugs 342 are used to close the diverter pipe 1 34 and the diverter pipe 2 341.

[0022] Example 2: Figure 1-Figure 2 ,

[0023] The bioreactor 15 comprises a base 1, a support rod 11 and a bioreactor 15. The support rod 11 is mounted on the upper end of the base 1, and the bioreactor 15 is mounted on the upper end of the support rod 11. The bioreactor 15 is provided with a support assembly 2 for stably supporting the bioreactor for biopharmaceuticals. The bottom of the bioreactor 15 is provided with a discharge assembly 3, and the discharge assembly 3 enables the bioreactor 15 to discharge smoothly.

[0024] The support assembly 2 includes a telescopic rod 21, a top plate 22 and a bearing 25. The telescopic rod 21 is installed at the upper end of the bioreactor 15. The telescopic rod 21 is used to drive the top plate 22 to rise and fall. The output end of the telescopic rod 21 is installed with a bearing 25, which facilitates the rotation of the top plate 22. The outer wall of the bearing 25 is installed with the top plate 22, and the top plate 22 is used to close the bioreactor 15. The lower end of the top plate 22 is respectively installed with a sealing ring 23 and a guide rod 24. The sealing ring 23 is used to seal the upper end of the bioreactor 15, and the guide rod 24 is used to limit the top plate 22 and also used to Guide lifting, the guide rod 24 is inserted into the upper end of the bioreactor 15, and a fixing block 26 is installed on the side end of the base 1. The fixing block 26 is fixed by bolts to make the bioreactor 15 support more stable. The upper end of the top plate 22 is respectively installed with a support tube 12 and a feed tube 14. The support tube 12 is used to support the feed tube 14. The upper end of the support tube 12 is installed with a motor A13, and the motor A13 is used to drive the stirring rod 16 to rotate. The output end of the motor A13 is connected to the stirring rod 16, and the stirring rod 16 is inserted into the bioreactor 15 to stir the reaction liquid in the bioreactor 15.

[0025] The working principle of the utility model is as follows: the fixing block 26 is fixed by bolts to make the bioreactor 15 support more stable, the top plate 22 is supported by the bearing 25 to rotate to the top of the bioreactor 15, the telescopic rod 21 drives the support top plate 22 to descend, the guide rod 24 is inserted into the upper end of the bioreactor 15, so that the top plate 22 is clamped on the upper end of the bioreactor 15, the motor A13 drives the stirring rod 16 to rotate, the stirring rod 16 is inserted into the bioreactor 15, the reaction liquid in the bioreactor 15 is stirred to accelerate the reaction, the pipe plug 342 is removed, the motor B32 drives the rotating rod 36 to rotate, the rotating rod 36 drives the scraper rod 1 37 and the scraper rod 2 38 to rotate, the scraper rod 1 37 stirs the sediment at the bottom of the bioreactor 15 to avoid blockage, the scraper rod 2 38 stirs the inside of the discharge pipe 33 to avoid blockage, the scraper rod 2 38 stirs the inside of the rotating rod 36 to avoid blockage, and the materials are discharged through the shunt pipe 1 34 and the shunt pipe 2 341 respectively.

[0026] Although the present invention has been described above with reference to the embodiments, various modifications may be made thereto and parts thereof may be replaced with equivalents without departing from the scope of the present invention. In particular, as long as there is no structural conflict, the various features in the embodiments disclosed in the present invention may be used in combination with each other in any manner, and the fact that these combinations are not exhaustively described in this specification is only for the sake of omitting space and saving resources. Therefore, the present invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims

1. A stably mounted biopharmaceutical bioreactor, comprising a base (1), a support rod (11) and a bioreactor (15), wherein the support rod (11) is mounted on the upper end of the base (1), and the bioreactor (15) is mounted on the upper end of the support rod (11), characterized in that: A support assembly (2) for stably supporting the bioreactor for biopharmaceuticals is arranged on the bioreactor (15); a discharge assembly (3) is arranged at the bottom of the bioreactor (15); the discharge assembly (3) comprises a motor seat (31) and a discharge pipe (33); the motor seat (31) is mounted on the base (1); the discharge pipe (33) is installed between the motor seat (31) and the bioreactor (15); a motor B (32) is installed inside the motor seat (31); a rotating rod (36) is rotatably installed inside the discharge pipe (33); a scraper rod 1 (37) is installed at the upper end of the rotating rod (36); a scraper rod 2 (38) is installed on the side wall of the rotating rod (36); A first shunt pipe (34) and a second shunt pipe (341) are respectively installed at the side ends of the discharge pipe (33); valves (35) are installed on the first shunt pipe (34) and the second shunt pipe (341); pipe plugs (342) are threadedly installed at the ends of the first shunt pipe (34) and the second shunt pipe (341); the support assembly (2) comprises a telescopic rod (21), a top plate (22) and a bearing (25); the telescopic rod (21) is installed at the upper end of the bioreactor (15); the output end of the telescopic rod (21) is installed with the bearing (25); the outer wall of the bearing (25) is installed with the top plate (22); and the discharge assembly (3) enables the bioreactor (15) to discharge smoothly.

2. A stably installed biopharmaceutical bioreactor according to claim 1, characterized in that: A sealing ring (23) and a guide rod (24) are respectively installed at the lower end of the top plate (22), the guide rod (24) is inserted into the upper end of the bioreactor (15), and a fixing block (26) is installed at the side end of the base (1).

3. A stably installed biopharmaceutical bioreactor according to claim 1, characterized in that: A support tube (12) and a feed tube (14) are respectively mounted on the upper end of the top plate (22); a motor A (13) is mounted on the upper end of the support tube (12); and an output end of the motor A (13) is connected to a stirring rod (16).

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