Liquid-phase tandem mass spectrometer for detecting organic matters

By designing a lifting mechanism driven by driving motor and ball screw in a liquid phase tandem mass spectrometer, as well as a combination of sealing plate and placement plate, the problem of lack of protection in the liquid phase tandem mass spectrometer in the prior art is solved, and the lifting and sealing protection of the instrument body is achieved, and the accuracy and stability of the detection results are improved.

CN222545291UActive Publication Date: 2025-02-28QINGDAO QINGMINT BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420055363.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-01-10
Publication Date
2025-02-28
Estimated Expiration
2034-01-10

AI Technical Summary

Technical Problem

The existing liquid phase tandem mass spectrometer lacks protective measures in idle state, and is susceptible to external force collision and extrusion and dust pollution, and the detection results are susceptible to interference from external factors, so the accuracy cannot be guaranteed.

Method used

A liquid phase tandem mass spectrometer is designed, using a lifting mechanism driven by a built-in drive motor and a ball screw in the chassis. Combined with the design of the sealing plate and the placement plate, the lifting and sealing protection of the instrument body is realized to ensure the stable placement and detection of organic matter.

Benefits of technology

Through lifting and sealing protection measures, the influence of external forces and dust is effectively prevented, the accuracy and stability of the detection results are improved, and the safety and reliability of the liquid-phase tandem mass spectrometer is ensured in idle state.

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Abstract

The utility model relates to the technical field of application protection of liquid-phase tandem mass spectrometers, in particular to a liquid-phase tandem mass spectrometer for detecting organic matters, which comprises a case and an instrument body. And a ball screw fixedly connected with the output end of the driving motor is rotationally mounted on the case through a star plate bracket. According to the utility model, the ball screw driven by the driving motor to rotate is arranged in the case, and the lifting nut on the ball screw is utilized to movably pull the guide block elastically supported by the strong spring and the lifting rod; the sealing plate capable of moving in an opening and closing mode is arranged at the opening position of the top end of the machine box, the sealing plate is movably dragged through the guide block, the synchronous rod and the traction supporting rod, and therefore opening and closing control over the machine box is achieved; therefore, the lifting liquid-phase tandem mass spectrometer body is used for carrying out targeted detection on the organic matters.
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Description

Technical Field

[0001] The utility model relates to the technical field of application protection of liquid phase tandem mass spectrometers, in particular to a liquid phase tandem mass spectrometer for detecting organic matter. Background Art

[0002] The excellent sensitivity of the mass spectrometry system of the liquid chromatography-tandem mass spectrometer can ensure the lowest detection limit for ultra-trace substances. It has high performance and reliability standards and is often used in the field of life sciences, from basic research to drug discovery and development, functional medicine, food safety and environmental analysis of pesticide residues, as well as forensic toxicology and trace analysis of clinical research.

[0003] Existing liquid phase tandem mass spectrometers, such as the one disclosed in announcement number CN211059663U, are used for detecting organic matter. When the mass spectrometer body needs to be fixed, the two threaded holes are turned in opposite directions by rotating the fixing handle, and the threaded holes contact and displace the outer threads of the threaded rod through the threaded holes. However, as a high-precision and advanced technical equipment, although the liquid phase tandem mass spectrometer adopts a movable and adjustable installation structure, it still adopts an exposed placement method, which makes it lack necessary protection measures when idle, especially the influence of external force collision, extrusion and dust pollution. The most critical thing is that the platform for placing the organic matter to be detected is also exposed with the liquid phase tandem mass spectrometer. Although the large operating space is convenient for manual observation and operation, it also makes the detection results susceptible to interference from many external factors, and the accuracy of the detection results cannot be guaranteed. Utility Model Content

[0004] The utility model aims to solve the problem in the prior art that it is difficult to apply protection to the instrument body of a liquid phase tandem mass spectrometer, and proposes a liquid phase tandem mass spectrometer for detecting organic matter.

[0005] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0006] A liquid phase tandem mass spectrometer for detecting organic matter comprises a chassis and an instrument body, wherein a driving motor and a star disk bracket are fixedly installed in the chassis, and a ball screw fixedly connected to an output end of the driving motor is rotatably installed in the chassis through the star disk bracket, and the chassis is provided with a supporting mechanism for supporting the lifting and retracting of the instrument body through the ball screw, and a sealing plate movably pulled by the supporting mechanism is symmetrically hingedly installed at an opening position at the top of the chassis, and the sealing plate is provided with a placing mechanism for placing organic matter.

[0007] Preferably, the drive motor and the star disk bracket are arranged in the chassis from bottom to top, and the ball screw is longitudinally arranged between the star disk brackets at the bottom end of the chassis.

[0008] Preferably, the supporting mechanism comprises a lifting nut matched with the ball screw, and a guide rod sliding through the bottom end of the chassis is fixedly connected to the lifting nut, guide grooves are symmetrically provided on the inner walls on both sides of the chassis, and strong springs and guide blocks welded to each other are provided in the guide grooves, a lifting rod is pin-mounted on the guide block, a traction rod is pin-connected between the lifting nut and the lifting rod, and a lifting platform is commonly pin-connected on the two lifting rods, a steering motor is fixedly installed in the lifting platform, and a horizontal turntable fixedly connected to the output end of the steering motor and used to fix the instrument body is rotatably installed on the lifting platform, and a limit rod sliding through the star disk bracket is integrally connected to the lifting platform.

[0009] Preferably, the strong spring is longitudinally welded inside the lower end of the guide groove, and the guide block is slidably mounted in the guide groove.

[0010] Preferably, a storage cavity connected to the guide groove is opened in the inner wall of the chassis, and a synchronization rod fixedly connected to the guide block is slidably sleeved in the storage cavity, and a traction support rod is pin-connected between the synchronization rod and the sealing plate.

[0011] Preferably, the placement mechanism includes a placement plate integrally connected to the sealing plate, a partition is fixedly connected to the placement plate, a T-shaped telescopic member is slidably sleeved in the partition, and a limiting plate is integrally connected to the T-shaped telescopic member, and a reset spring is welded between the limiting plate and the partition.

[0012] Preferably, the placement plate is perpendicular to the sealing plate, and the return spring is sleeved on the T-shaped telescopic member.

[0013] Compared with the prior art, the utility model has the following advantages:

[0014] 1. The utility model sets a ball screw driven to rotate by a driving motor in the chassis, and uses the lifting nut on the ball screw to movably pull the guide block and the lifting rod elastically supported by a strong spring, thereby pulling the lifting platform and the horizontal turntable to perform lifting movement, thereby realizing the lifting movement of the liquid phase tandem mass spectrometer body in the chassis.

[0015] 2. The utility model sets a sealing plate that can be opened and closed at the top opening of the chassis, and uses a guide block, a synchronization rod and a traction support rod to movably pull the sealing plate, thereby realizing the opening and closing control of the chassis. At the same time, the sealing plate is used to set a placement plate for placing organic matter, so that the organic matter is specifically detected by using a liftable liquid phase tandem mass spectrometer body. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a schematic diagram of the structure of a liquid phase tandem mass spectrometer for detecting organic matter proposed in the utility model;

[0017] Figure 2This is a cross-sectional view of a liquid phase tandem mass spectrometer for detecting organic matter proposed by the utility model;

[0018] Figure 3 This is a schematic diagram of the enlarged structure of part A of a liquid phase tandem mass spectrometer for detecting organic matter proposed by the utility model;

[0019] Figure 4 This is a schematic diagram of the enlarged structure of part B of a liquid phase tandem mass spectrometer for detecting organic matter proposed by the utility model.

[0020] In the figure: 1. chassis; 2. drive motor; 3. star disk bracket; 4. ball screw; 5. lifting nut; 6. guide rod; 7. guide groove; 8. strong spring; 9. guide block; 10. lifting rod; 11. lifting platform; 12. traction rod; 13. steering motor; 14. horizontal turntable; 15. instrument body; 16. sealing plate; 17. storage chamber; 18. synchronization rod; 19. traction support rod; 20. placement plate; 21. partition; 22. T-type telescopic member; 23. limit plate; 24. reset spring; 25. limit rod. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0022] Reference Figure 1-Figure 4 A liquid phase tandem mass spectrometer for detecting organic matter includes a chassis 1 and an instrument body 15. It should be noted that according to the use of the liquid phase tandem mass spectrometer, the instrument body 15 needs to be lifted and lowered in the chassis 1 to achieve storage management. A drive motor 2 and a star disk bracket 3 are fixedly installed in the chassis 1, and a ball screw 4 fixedly connected to the output end of the drive motor 2 is rotatably installed in the chassis 1 through the star disk bracket 3, and the rotational movement of the ball screw 4 is realized under the driving action of the drive motor 2.

[0023] The chassis 1 is provided with a supporting mechanism for supporting the lifting and telescoping of the instrument body 15 through the ball screw 4. The supporting mechanism includes a lifting nut 5 matched with the ball screw 4, and a guide rod 6 sliding through the bottom end of the chassis 1 is fixedly connected to the lifting nut 5. Guide grooves 7 are symmetrically provided on the inner walls of both sides of the chassis 1, and a strong spring 8 and a guide block 9 welded to each other are provided in the guide groove 7. A lifting rod 10 is installed on the pin shaft of the guide block 9. A traction rod 12 is connected to the lifting nut 5 and the lifting rod 10 through the pin shaft, and a lifting platform 11 is connected to the common pin shaft of the two lifting rods 10. The lifting nut 5 moves up and down through the lifting nut 5. The lifting rod 10 is pulled by the traction rod 12, so that the guide block 9 moves up and down in the guide groove 7, so that the lifting platform 11 moves up and down. A steering motor 13 is fixedly installed in the lifting platform 11, and a horizontal turntable 14 fixedly connected to the output end of the steering motor 13 and used to fix the instrument body 15 is rotatably installed on the lifting platform 11. A limit rod 25 that slides through the star disk bracket 3 is integrally connected to the lifting platform 11. Controlling the steering motor 13 can make the liquid phase tandem mass spectrometer body 15 on the horizontal turntable 14 deflect horizontally, so as to detect organic matter located on the placement plate 20.

[0024] A sealing plate 16 movably pulled by a supporting mechanism is symmetrically hingedly installed at the top opening position of the chassis 1. A storage cavity 17 connected to the guide groove 7 is opened in the inner wall of the chassis 1, and a synchronization rod 18 fixedly connected to the guide block 9 is slidably sleeved in the storage cavity 17. A traction support rod 19 is pin-connected between the synchronization rod 18 and the sealing plate 16. When the guide block 9 moves up and down, the sealing plate 16 is pulled by the synchronization rod 18 and the traction support rod 19 to deflect, thereby realizing the opening and closing of the chassis 1.

[0025] The sealing plate 16 is provided with a placement mechanism for placing organic matter, and the placement mechanism includes a placement plate 20 integrally connected to the sealing plate 16, a partition plate 21 is fixedly connected to the placement plate 20, a T-shaped telescopic member 22 is slidably sleeved in the partition plate 21, and a limiting plate 23 is integrally connected to the T-shaped telescopic member 22, and a reset spring 24 is welded between the limiting plate 23 and the partition plate 21, and under the tension of the reset spring 24, the limiting plate 23 can clamp and limit the organic matter located on the placement plate 20.

[0026] The driving motor 2 and the star disk bracket 3 are arranged in the chassis 1 from bottom to top, and the ball screw 4 is longitudinally arranged between the star disk bracket 3 at the bottom end of the chassis 1. The center plate of the star disk bracket 3 is composed of four circumferentially equidistant cross plates.

[0027] The strong spring 8 is longitudinally welded in the lower end of the guide groove 7, and the guide block 9 is slidably sleeved in the guide groove 7, and the guide block 9 that moves up and down is used to support the lifting rod 10 to move up and down and deflect.

[0028] The placement plate 20 is perpendicular to the sealing plate 16 , and the return spring 24 is sleeved on the T-shaped telescopic member 22 .

[0029] It should be noted that the specific models and specifications of the drive motor 2, the steering motor 13 and the liquid phase tandem mass spectrometer body 15 need to be selected and determined according to the actual specifications of the device, and the specific selection calculation method adopts the existing technology in this field, so it is not repeated here.

[0030] The functional principle of the utility model can be explained through the following operation modes:

[0031] When the liquid phase tandem mass spectrometer body 15 needs to be used, the driving motor 2 is controlled to start;

[0032] The output end of the driving motor 2 drives the ball screw 4 to rotate, and the ball screw 4 drives the lifting nut 5 to move upward. The lifting nut 5 supports the lifting rod 10 and the guide block 9 to move upward in the guide groove 7 through the traction rod 12, so as to support the lifting platform 11 to move upward;

[0033] The guide block 9 supports the sealing plate 16 through the synchronous rod 18 and the traction support rod 19, so that the sealing plate 16 tends to be vertical, and the placement plate 20 tends to be horizontal;

[0034] The organic matter is placed horizontally on the placement plate 20, and the limit plate 23 effectively fixes the organic matter under the tension of the return spring 24;

[0035] The steering motor 13 is controlled to start on the lifting platform 11, and the instrument body 15 is driven to perform horizontal deflection through the horizontal turntable 14, so that the instrument body 15 can detect organic matter at different positions.

[0036] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A liquid phase tandem mass spectrometer for detecting organic matter, comprising a chassis (1) and an instrument body (15), characterized in that: The chassis (1) is fixedly mounted with a drive motor (2) and a star disk bracket (3), and the chassis (1) is rotatably mounted with a ball screw (4) fixedly connected to the output end of the drive motor (2) via the star disk bracket (3); the chassis (1) is provided with a support mechanism for supporting the instrument body (15) to rise, fall and extend via the ball screw (4); a sealing plate (16) movably pulled by the support mechanism is symmetrically hingedly mounted at the top opening of the chassis (1), and the sealing plate (16) is provided with a placement mechanism for placing organic matter.

2. A liquid phase tandem mass spectrometer for detecting organic matter according to claim 1, characterized in that: The driving motor (2) and the star disk bracket (3) are arranged in the chassis (1) from bottom to top, and the ball screw (4) is longitudinally arranged between the star disk bracket (3) at the bottom end of the chassis (1).

3. A liquid phase tandem mass spectrometer for detecting organic matter according to claim 1, characterized in that: The support mechanism comprises a lifting nut (5) matched with the ball screw (4), and a guide rod (6) which slides through the bottom end of the chassis (1) is fixedly connected to the lifting nut (5), and guide grooves (7) are symmetrically provided on the inner walls of both sides of the chassis (1), and a strong spring (8) and a guide block (9) which are welded to each other are arranged in the guide grooves (7), and a lifting rod (10) is pin-mounted on the guide block (9), and a traction rod (12) is pin-mounted between the lifting nut (5) and the lifting rod (10), and a lifting platform (11) is pin-mounted on the two lifting rods (10), and a steering motor (13) is fixedly installed in the lifting platform (11), and a horizontal turntable (14) which is fixedly connected to the output end of the steering motor (13) and is used to fix the instrument body (15) is rotatably installed on the lifting platform (11), and a limit rod (25) which slides through the star disk bracket (3) is integrally connected to the lifting platform (11).

4. A liquid phase tandem mass spectrometer for detecting organic matter according to claim 3, characterized in that: The strong spring (8) is longitudinally welded inside the lower end of the guide groove (7), and the guide block (9) is slidably mounted in the guide groove (7).

5. A liquid phase tandem mass spectrometer for detecting organic matter according to claim 3, characterized in that: The inner wall of the chassis (1) is provided with a storage cavity (17) connected to the guide groove (7), and a synchronization rod (18) fixedly connected to the guide block (9) is slidably sleeved in the storage cavity (17), and a traction support rod (19) is pin-connected between the synchronization rod (18) and the sealing plate (16).

6. A liquid phase tandem mass spectrometer for detecting organic matter according to claim 1, characterized in that: The placement mechanism comprises a placement plate (20) integrally connected to the sealing plate (16), a partition plate (21) being fixedly connected to the placement plate (20), a T-shaped telescopic member (22) being slidably sleeved on the partition plate (21), a limiting plate (23) being integrally connected to the T-shaped telescopic member (22), and a return spring (24) being welded between the limiting plate (23) and the partition plate (21).

7. A liquid phase tandem mass spectrometer for detecting organic matter according to claim 6, characterized in that: The placement plate (20) is perpendicular to the sealing plate (16), and the return spring (24) is sleeved on the T-shaped telescopic member (22).

Citation Information

Patent Citations

  • Liquid phase tandem mass spectrometer for detecting organic matters

    CN211059663U