Experimental device for withdrawing reflex of mouse abdominal wall

By designing a mouse abdominal wall retreat reflection experimental device including a transparent box, clamp and fixing, the problem of poor fixation effect of acrylic box on mice was solved, and the stable fixation of the mouse and the smooth progress of the experimental process was achieved.

CN222549399UActive Publication Date: 2025-03-04HUNAN UNIV OF CHINESE MEDICINE
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202420653039.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-01
Publication Date
2025-03-04
Estimated Expiration
2034-04-01

AI Technical Summary

Technical Problem

In the prior art, the acrylic box has poor fixation effect on mice, causing the mice to turn back and bite the catheter, affecting the experimental process.

Method used

An experimental device for mouse abdominal wall withdrawal reflex is designed, including a transparent box, a first fixing assembly and a second fixing assembly. The first fixing assembly clamps the mouse's neck through a clamping piece, and fixes the mouse in a transparent box with the fixing piece to prevent back-returning and damaging the catheter. The second fixing assembly allows the catheter to pass through and fits the fixing member and clamping member to completely secure the mouse in the transparent box.

Benefits of technology

It effectively prevents mice from returning to damage the catheter, ensures the smooth progress of the experiment, improves the convenience and fixation effect of the experiment, and is suitable for animals of different sizes.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN222549399U_ABST
    Figure CN222549399U_ABST
Patent Text Reader

Abstract

The utility model provides a mouse abdominal wall withdrawing reflex experiment device, which comprises a placing assembly, a first fixing assembly and a second fixing assembly, and is characterized in that the placing assembly comprises a transparent box, and the transparent box is arranged along a first direction in a penetrating manner. The first fixing assembly comprises a fixing piece and a clamping piece, the fixing piece is detachably installed in the transparent box and can move in the first direction, and the clamping piece is installed on the fixing piece, can move in the second direction and is further configured to be used for clamping the neck of an animal. The second fixing assembly is detachably installed in the transparent box, can move in the first direction and is further configured to allow a catheter to penetrate through. According to the mouse abdominal wall withdrawal reflex experiment device, the clamping piece is adopted, the situation that an animal turns back to damage a guide pipe and affect the experiment process can be prevented, experiment proceeding is facilitated, and use convenience is improved.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model belongs to the technical field of mouse experiments, and in particular relates to a mouse abdominal wall withdrawal reflex experimental device. Background Art

[0002] The abdominal withdrawal reflex test evaluates the behavioral response of animals by expanding the intestines. It is currently the most widely used method for evaluating the sensitivity of animal viscera. During the experiment, the experimenter first placed the mouse in a transparent acrylic box. Then the mouse's colon was inflated through an air bag and a catheter to expand the mouse's colon. Under the stimulation of the colon, the mouse will lift its abdomen. The experimenter can control the height of the mouse's abdomen by controlling the amount of inflation. However, in order for the experimenter to be able to smoothly observe the lifting of the mouse's abdomen, the acrylic box needs to reserve a certain amount of space for the mouse to lift its abdomen. Therefore, after the catheter is inserted into the mouse's colon, the mouse can turn back in the acrylic box and bite off the catheter, affecting the progress of the experiment. Utility Model Content

[0003] The purpose of the embodiment of the present application is to provide a mouse abdominal wall withdrawal reflex experimental device to solve the technical problem that the acrylic box in the prior art has a poor fixation effect on the mouse.

[0004] To achieve the above purpose, the technical solution adopted in this application is: to provide a mouse abdominal wall withdrawal reflex experimental device, including:

[0005] A placement component, the placement component comprising a transparent box, the transparent box is arranged through along a first direction;

[0006] A first fixing assembly, comprising a fixing member and a clamping member, wherein the fixing member is detachably mounted in the transparent box and is movable in a first direction, and the clamping member is mounted on the fixing member and is movable in a second direction, and is further configured to be capable of clamping the neck of an animal;

[0007] The second fixing component is detachably installed in the transparent box, can move along the first direction, and is configured to allow a catheter to pass through.

[0008] Optionally, the clamping member includes two clamping plates and two locking structures, the two clamping plates are installed on the fixing member and can move along the second direction, the two locking structures are respectively installed at both ends of the two clamping plates and are configured to lock the two clamping plates.

[0009] Optionally, the clamping plate includes a first locking plate, a second locking plate and an arc-shaped plate, and the arc-shaped plate is connected between the first locking plate and the second locking plate.

[0010] Optionally, the locking structure includes a locking bolt and a locking nut, the locking bolt is passed through the two first locking plates or the two second locking plates, the locking nut is threaded on the locking bolt, and can lock the two first locking plates or the two second locking plates.

[0011] Optionally, the transparent box is provided with a plurality of first slide grooves, which are respectively provided on both sides of the transparent box along the second direction; the fixing member includes a fixing frame, which is detachably installed in the transparent box and can be moved along the first direction; the clamping member includes a plurality of guide rods, which are respectively connected to the two clamping plates, and are arranged through the fixing frame, and are arranged one-to-one with the plurality of first slide grooves.

[0012] Optionally, the transparent box is provided with two second slide grooves, and the two second slide grooves are respectively provided on both sides of the transparent box along the third direction; the fixing member also includes two first screws and two first nuts, the two first screws are respectively connected to the two sides of the fixing frame along the third direction, and are arranged one-to-one with the two second slide grooves, and the two first nuts are respectively screwed to the two first screws and are located outside the transparent box.

[0013] Optionally, the second fixing assembly includes a fixing plate and a first avoidance groove, the fixing plate is detachably mounted in the transparent box and is movable along a first direction, and the first avoidance groove is provided on the fixing plate.

[0014] Optionally, the second fixing assembly also includes two second screws and two second nuts, the two second screws are respectively connected to the two sides of the fixing plate along the third direction, and are arranged one-to-one with the two second slide grooves, and the two second nuts are respectively screwed to the two second screws and are located outside the transparent box.

[0015] Optionally, the fixing plate is provided with a second avoidance groove, which is connected to the first avoidance groove and is located at the end of the first avoidance groove in the second direction, and the width of the first avoidance groove in the third direction is smaller than the width of the second avoidance groove in the third direction.

[0016] Optionally, the placement assembly further includes a plurality of legs, each of which is connected to the transparent box and is used to support the transparent box.

[0017] The beneficial effects of the mouse abdominal wall withdrawal reflex experimental device provided by the present application are:

[0018] The mouse abdominal wall withdrawal reflex experimental device provided in the embodiment of the present application adopts a clamping member that can clamp the neck of the mouse. With the cooperation of the fixing member, the animal can be placed in a transparent box to prevent the animal from turning back and damaging the catheter to affect the experimental process, which is convenient for the experiment and helps to improve the convenience of use. In addition, after the animal is placed in the transparent box, the clamping member can be prevented from moving in the first direction, and then the animal can be prevented from moving in the first direction to affect the lifting height of the abdominal wall in the second direction, which is convenient for the experimenter to observe the lifting of the abdominal wall. In addition, since the fixing member can move in the first direction, the experimenter can adjust the distance between the fixing member and the second fixing component according to the size of the animal, which can be suitable for animals of different sizes, which helps to improve the scope of application of the device. With the second fixing component, with the cooperation of the fixing member and the clamping member, the animal can be completely fixed in the transparent box so that the animal can only move in the second direction, which is convenient for the experiment and has a good fixing effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0020] Figure 1 A first-perspective stereoscopic image of a mouse abdominal wall withdrawal reflex experimental device provided in an embodiment of the present application;

[0021] Figure 2 A second perspective stereoscopic image of a mouse abdominal wall withdrawal reflex experimental device provided in an embodiment of the present application;

[0022] Figure 3 for Figure 1 A partial enlarged view of point A in the middle.

[0023] Among them, the reference numerals in the figure are:

[0024] 1. Place components; 11. Transparent box; 12. First slide slot; 13. Second slide slot; 14. Support legs;

[0025] 2. First fixing assembly; 21. Fixing member; 211. Fixing frame; 212. First screw rod; 213. First nut; 22. Clamping member; 221. Clamping plate; 2211. First locking plate; 2212. Second locking plate; 2213. Arc plate; 222. Locking structure; 2221. Locking bolt; 2222. Locking nut; 223. Guide rod;

[0026] 3. Second fixing assembly; 31. Fixing plate; 32. First avoidance groove; 33. Second screw rod; 34. Second nut; 35. Second avoidance groove. DETAILED DESCRIPTION

[0027] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present application more clearly understood, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0028] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it can be directly on the other element or indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or indirectly connected to the other element.

[0029] It should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0030] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0031] like Figures 1 to 3 As shown, the embodiment of the present application provides a mouse abdominal wall withdrawal reflex experimental device, including a placement component 1, a first fixing component 2 and a second fixing component 3. The placement component 1 includes a transparent box 11, and the transparent box 11 is arranged through along a first direction. The first fixing component 2 includes a fixing member 21 and a clamping member 22. The fixing member 21 is detachably mounted in the transparent box 11 and can move along the first direction. The clamping member 22 is mounted on the fixing member 21 and can move along the second direction. It is also configured to be used to clamp the neck of the animal. The second fixing component 3 is detachably mounted in the transparent box 11 and can move along the first direction. It is also configured to allow a catheter to pass through.

[0032] It should be noted that the first direction mentioned above and below refers to the bidirectional direction of the shortest connection line between the two ends of the transparent box 11 in the through direction. Figure 1 The second direction above and below refers to the bidirectional direction along its axis, as shown in FIG. Figure 1 The Y-axis shown in .

[0033] It should be noted that, in the present embodiment, the animal is set as a mouse as an example for explanation. Of course, in other embodiments, according to actual application requirements, other types of animals can also be set, which is not limited here.

[0034] Specifically, when using the device, the experimenter clamps the mouse's neck with the clamp 22. After clamping the clamp 22 on the mouse's neck, the experimenter installs the fixing member 21 to the transparent box 11. The experimenter adjusts the position of the fixing member 21 in the first direction of the transparent box 11 according to the size of the mouse until the mouse completely enters the transparent box 11. The experimenter then installs the second fixing component 3 into the transparent box 11, and the mouse is now located between the fixing member 21 and the second fixing component 3 and inside the transparent box 11. When conducting the experiment, the experimenter passes the catheter through the second fixing component 3 to insert the catheter into the mouse's colon. The experimenter inflates the mouse's colon through the airbag, and the mouse's colon begins to expand. Under the stimulation of the colon, the mouse raises its abdomen in the second direction. At the same time, driven by the mouse's abdomen, the mouse's neck also rises in the second direction. The experimenter continues to inflate the colon, and the mouse continues to raise its abdomen in the second direction, and the mouse's neck also continues to rise in the second direction until the experiment ends. After the experiment is over, the experimenter removes the second fixing component 3 from the transparent box 11 and removes the fixing member 21 from the transparent box 11, then takes the mouse out of the transparent box 11, and finally removes the clamping member 22 from the neck of the mouse.

[0035] The mouse abdominal wall withdrawal reflex experimental device provided by the present application adopts a clamping member 22, which can clamp the neck of the mouse. With the cooperation of the fixing member 21, the animal can be placed in the transparent box 11 to prevent the animal from turning back to damage the catheter and affect the experimental process, which is convenient for the experiment and helps to improve the convenience of use. In addition, after the animal is placed in the transparent box 11, the clamping member 22 can be prevented from moving in the first direction, and then the animal can be prevented from moving in the first direction to affect the lifting height of the abdominal wall in the second direction, which is convenient for the experimenter to observe the lifting of the abdominal wall. Similarly, since the clamping member 22 can move in the second direction, when the animal lifts the abdomen, the clamping member 22 can be prevented from affecting the movement of the animal's neck, which is convenient for the experiment. In addition, since the fixing member 21 can move in the first direction, the experimenter can adjust the distance between the fixing member 21 and the second fixing component 3 according to the size of the animal, which can be applicable to animals of different sizes, which helps to improve the scope of application of the device. By using the second fixing assembly 3, the animal can be completely fixed in the transparent box 11 under the cooperation of the fixing member 21 and the clamping member 22, so that the animal can only move along the second direction, which is convenient for the experiment and has a good fixing effect. By using the transparent box 11, the experimenter can directly observe the inside from the outside, which is convenient for the experimenter to observe the lifting of the animal's abdomen.

[0036] Optionally, the cross-sectional shape of the transparent box 11 perpendicular to the first direction is set to be a rectangle.

[0037] Compared with other shapes, during the experiment, the transparent box 11 with a rectangular cross-section is convenient for the animal to stand, avoiding the animal's difficulty in standing and affecting the lifting of the abdomen, making it easier for the experimenter to observe the lifting of the animal's abdomen.

[0038] In one embodiment of the present application, see Figures 1 to 3 The clamping member 22 includes two clamping plates 221 and two locking structures 222. The two clamping plates 221 are installed on the fixing member 21 and can move along the second direction. The two locking structures 222 are respectively installed at both ends of the two clamping plates 221 and are configured to lock the two clamping plates 221.

[0039] Specifically, when it is necessary to clamp the mouse neck, the experimenter places the mouse neck between the two clamping plates 221. The experimenter drives the two clamping plates 221 to move toward each other through the two locking structures 222 until the two clamping plates 221 and the mouse neck are roughly fitted. When it is necessary to remove the clamping member 22, the experimenter releases the position limit of the two clamping plates 221 by the locking structure 222, and the two clamping plates 221 can move back to back, and the mouse can be taken out from between the two clamping plates 221.

[0040] With such a configuration, two locking structures 222 are used to clamp the neck of the animal between the two clamping plates 221, and the animal can also be taken out from between the two clamping plates 221, which is convenient to use. During the experiment, the catheter can be damaged by turning the animal's head back, which is convenient for the experiment. In addition, when the size of the mouse's neck changes, the distance between the two clamping plates 221 can be adjusted through the two locking structures 222, so that the clamping member 22 can be used to clamp mice of different sizes, which helps to further improve the scope of application of the device.

[0041] In one embodiment of the present application, please refer to Figures 1 to 3 The clamping plate 221 includes a first locking plate 2211 , a second locking plate 2212 and an arc plate 2213 , and the arc plate 2213 is connected between the first locking plate 2211 and the second locking plate 2212 .

[0042] In this arrangement, the first locking plate 2211 and the second locking plate 2212 are used. With the cooperation of the two locking structures 222, the distance between the two arc plates 2213 can be adjusted, so that animals of different sizes can be used, which helps to further improve the scope of application. In addition, during the experiment, the two arc plates 2213 can be limited so that the two arc plates 2213 always roughly fit the neck of the animal, and the fixing effect is good. The arc plate 2213 can fit the neck of the animal more closely, and the clamping effect is good.

[0043] In one embodiment of the present application, see Figures 1 to 3 The locking structure 222 includes a locking bolt 2221 and a locking nut 2222. The locking bolt 2221 is passed through the two first locking plates 2211 or the two second locking plates 2212. The locking nut 2222 is screwed to the locking bolt 2221 and can lock the two first locking plates 2211 or the two second locking plates 2212.

[0044] It should be noted that one of the locking bolts 2221 passes through the two first locking plates 2211 , and the other locking bolt 2221 passes through the two second locking plates 2212 .

[0045] In this arrangement, using the locking bolt 2221 and the locking nut 2222, the experimenter can rotate the locking nut 2222 to reduce the distance between the locking nut 2222 and the head of the locking bolt 2221, so that the two first locking plates 2211 or the two second locking plates 2212 can move toward each other, thereby reducing the distance between the two arc plates 2213. Conversely, the experimenter can rotate the locking nut 2222 to increase the distance between the locking nut 2222 and the head of the locking bolt 2221, thereby increasing the distance between the two arc plates 2213. In summary, the distance between the two arc plates 2213 can be adjusted by the locking bolt 2221 and the locking nut 2222, so that the clamping member 22 can clamp animals of different sizes, which helps to further improve the scope of application and has a good clamping effect.

[0046] In one embodiment of the present application, see Figures 1 to 3 The transparent box 11 is provided with a plurality of first slide grooves 12, which are respectively provided on both sides of the transparent box 11 along the second direction. The fixing member 21 includes a fixing frame 211, which is detachably mounted in the transparent box 11 and can move along the first direction. The clamping member 22 includes a plurality of guide rods 223, which are respectively connected to the two clamping plates 221, and are provided through the fixing frame 211, and are provided one by one corresponding to the plurality of first slide grooves 12.

[0047] It should be noted that in this embodiment, the number of the first chute 12 and the number of the guide rods 223 are both set to six for illustration. Of course, in other embodiments, according to actual application requirements, the first chute 12 and the guide rods 223 can also be set to two, three, four, five, seven... other numbers, which are not limited here. In this embodiment, three of the first chute 12 are opened on one side of the transparent box 11 along the second direction, and the other three first chute 12 are opened on the other side of the transparent box 11 along the second direction.

[0048] With such arrangement, after the neck of the animal is clamped in the clamping member 22, the experimenter installs the clamping member 22 to the target position in the transparent box 11 through the fixed frame 211 according to the size of the animal. The fixed frame 211 is adopted, and multiple guide rods 223 can be passed through. The fixed frame 211 can drive the two clamping plates 221 to move along the first direction through the multiple guide rods 223, which is convenient for the experimenter to place the animal in the transparent box 11, and helps to improve the convenience of use. During the experiment, when the animal raises its abdomen along the second direction, the two clamping plates 221 can be guided under the cooperation of the fixed frame 211 and the multiple guide rods 223, so that the neck and abdomen of the animal can only move along the second direction, which is convenient for the experimenter to observe the lifting of the abdomen. The multiple first chutes 12 are adopted, and the multiple guide rods 223 can be avoided, which is convenient for the experimenter to place the animal in the transparent box 11. Furthermore, when placing the animal in the transparent box 11, the plurality of guide rods 223 can guide the fixed frame 211 and the two clamping plates 221 along the first direction, which helps to improve the movement stability of the fixed frame 211 and the two clamping plates 221 in the first direction, making it easier for the experimenter to place the animal in the transparent box 11, thereby improving the convenience of use.

[0049] In one embodiment of the present application, please refer to Figures 1 to 3 The transparent box 11 is provided with two second slide grooves 13, and the two second slide grooves 13 are respectively provided on both sides of the transparent box 11 along the third direction. The fixing member 21 also includes two first screw rods 212 and two first nuts 213, the two first screw rods 212 are respectively connected to both sides of the fixing frame 211 along the third direction, and are arranged one-to-one with the two second slide grooves 13, and the two first nuts 213 are respectively screwed to the two first screw rods 212 and are located outside the transparent box 11.

[0050] In this way, by using two first screw rods 212 and two first nuts 213, the fixed frame 211 can be detachably connected with the transparent box 11, and the disassembly and installation are convenient. By using the second slide groove 13, the first screw rod 212 can be avoided, which is convenient for the experimenter to place the animal in the transparent box 11. In addition, when the animal is placed in the transparent box 11, the two first screw rods 212 can guide the fixed frame 211 and the two clamping plates 221 along the first direction, which helps to improve the movement stability of the fixed frame 211 and the two clamping plates 221 in the first direction, and is convenient for the experimenter to place the animal in the transparent box 11, which helps to improve the convenience of use.

[0051] In one embodiment of the present application, see Figures 1 to 3 The second fixing assembly 3 includes a fixing plate 31 and a first avoiding groove 32 . The fixing plate 31 is detachably mounted in the transparent box 11 and can move along a first direction. The first avoiding groove 32 is formed in the fixing plate 31 .

[0052] In this arrangement, the fixing plate 31 can be used to completely fix the animal in the transparent box 11 with the cooperation of the first fixing component 2, so that the animal can only move along the second direction, which is convenient for the experiment and has a good fixing effect. The first avoidance groove 32 can avoid the tail of the animal and the catheter during the experiment to prevent the fixing plate 31 from interfering with the tail of the animal and the catheter, thereby affecting the lifting of the animal's abdomen.

[0053] In one embodiment of the present application, see Figures 1 to 3 The second fixing assembly 3 also includes two second screws 33 and two second nuts 34. The two second screws 33 are respectively connected to the two sides of the fixing plate 31 along the third direction, and are arranged one-to-one with the two second slide grooves 13. The two second nuts 34 are respectively screwed to the two second screws 33 and are located outside the transparent box 11.

[0054] It should be noted that the second directions above and below refer to the bidirectional directions along the axis. Figure 1 The Z axis shown in .

[0055] In this way, by using two second screws 33 and two second nuts 34, the fixing plate 31 can be detachably connected to the transparent box 11, and the removal and installation are convenient. By using the second slide groove 13, the second screw 33 can be avoided, which is convenient for the experimenter to place the fixing plate 31 in the transparent box 11. In addition, when the fixing plate 31 is placed in the transparent box 11, the fixing plate 31 can be guided along the first direction by the two second screws 33, which helps to improve the movement stability of the fixing plate 31 in the first direction and helps to improve the convenience of use.

[0056] In one embodiment of the present application, please refer to Figures 1 to 3 The fixing plate 31 is provided with a second avoidance groove 35, which is connected to the first avoidance groove 32 and is located at the end of the first avoidance groove 32 in the second direction. The width of the first avoidance groove 32 in the third direction is smaller than the width of the second avoidance groove 35 in the third direction.

[0057] In this configuration, since the width of the first avoidance groove 32 in the third direction is smaller than the width of the second avoidance groove 35 in the third direction, it is convenient for the experimenter to place the catheter into the colon of the animal during the experiment, which helps to improve the convenience of use.

[0058] In one embodiment of the present application, see Figures 1 to 3 The placement component 1 also includes a plurality of legs 14 , which are all connected to the transparent box 11 and used to support the transparent box 11 .

[0059] With such arrangement, a plurality of legs 14 are used to support the transparent box 11 so that the transparent box 11 and the desktop maintain a certain distance, which facilitates the movement of the guide rod 223 and prevents the desktop from interfering with the movement of the guide rod 223 .

[0060] One or more embodiments of the present application are intended to cover all such substitutions, modifications and variations that fall within the broad scope of the present application. Therefore, any omissions, modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of one or more embodiments of the present application should be included in the protection scope of the present application.

Claims

1. A mouse abdominal wall withdrawal reflex experimental device, characterized in that: include: A placement component (1), the placement component (1) comprising a transparent box (11), the transparent box (11) being arranged to penetrate along a first direction; A first fixing component (2), the first fixing component (2) comprising a fixing member (21) and a clamping member (22), the fixing member (21) being detachably mounted in the transparent box (11) and being movable in a first direction, the clamping member (22) being mounted on the fixing member (21) and being movable in a second direction, and being configured to be capable of clamping the neck of an animal; A second fixing component (3), the second fixing component (3) is detachably mounted in the transparent box (11), is movable along a first direction, and is configured to allow a catheter to pass through.

2. The mouse abdominal wall withdrawal reflex experimental device as claimed in claim 1, characterized in that: The clamping member (22) comprises two clamping plates (221) and two locking structures (222); the two clamping plates (221) are mounted on the fixing member (21) and are capable of moving along the second direction; the two locking structures (222) are respectively mounted on two ends of the two clamping plates (221) and are configured to lock the two clamping plates (221).

3. The mouse abdominal wall withdrawal reflex experimental device as claimed in claim 2, characterized in that: The clamping plate (221) comprises a first locking plate (2211), a second locking plate (2212) and an arc-shaped plate (2213); the arc-shaped plate (2213) is connected between the first locking plate (2211) and the second locking plate (2212).

4. The mouse abdominal wall withdrawal reflex experimental device as claimed in claim 3, characterized in that: The locking structure (222) comprises a locking bolt (2221) and a locking nut (2222); the locking bolt (2221) is passed through the two first locking plates (2211) or the two second locking plates (2212); the locking nut (2222) is screwed to the locking bolt (2221) and is capable of locking the two first locking plates (2211) or the two second locking plates (2212).

5. The mouse abdominal wall withdrawal reflex experimental device as claimed in claim 2, characterized in that: The transparent box (11) is provided with a plurality of first slide grooves (12), and the plurality of first slide grooves (12) are respectively provided on both sides of the transparent box (11) along the second direction; the fixing member (21) comprises a fixing frame (211), and the fixing frame (211) is detachably installed in the transparent box (11) and is movable along the first direction; the clamping member (22) comprises a plurality of guide rods (223), and the plurality of guide rods (223) are respectively connected to the two clamping plates (221), and are arranged through the fixing frame (211), and are arranged one-to-one corresponding to the plurality of first slide grooves (12).

6. The mouse abdominal wall withdrawal reflex experimental device as claimed in claim 5, characterized in that: The transparent box (11) is provided with two second slide grooves (13), and the two second slide grooves (13) are respectively provided on both sides of the transparent box (11) along the third direction; the fixing member (21) further comprises two first screw rods (212) and two first nuts (213), the two first screw rods (212) are respectively connected to both sides of the fixing frame (211) along the third direction, and are arranged in a one-to-one correspondence with the two second slide grooves (13), and the two first nuts (213) are respectively screwed to the two first screw rods (212), and are located outside the transparent box (11).

7. The mouse abdominal wall withdrawal reflex experimental device as claimed in claim 6, characterized in that: The second fixing assembly (3) comprises a fixing plate (31) and a first avoidance groove (32); the fixing plate (31) is detachably mounted in the transparent box (11) and is movable along a first direction; the first avoidance groove (32) is formed in the fixing plate (31).

8. The mouse abdominal wall withdrawal reflex experimental device as claimed in claim 7, characterized in that: The second fixing assembly (3) further comprises two second screw rods (33) and two second nuts (34); the two second screw rods (33) are respectively connected to two sides of the fixing plate (31) along the third direction and are arranged in a one-to-one correspondence with the two second slide grooves (13); the two second nuts (34) are respectively screwed to the two second screw rods (33) and are located outside the transparent box (11).

9. The mouse abdominal wall withdrawal reflex experimental device as claimed in claim 8, characterized in that: The fixing plate (31) is provided with a second avoidance groove (35), the second avoidance groove (35) is connected to the first avoidance groove (32) and is located at the end of the first avoidance groove (32) in the second direction, and the width of the first avoidance groove (32) in the third direction is smaller than the width of the second avoidance groove (35) in the third direction.

10. The mouse abdominal wall withdrawal reflex experimental device according to claim 1, characterized in that: The placement assembly (1) further comprises a plurality of supporting legs (14), wherein the plurality of supporting legs (14) are all connected to the transparent box (11) and are used to support the transparent box (11).