Micro-channel reactor for pharmacy

Abstract

The utility model discloses a pharmaceutical microchannel reactor which comprises a plurality of microchannel reaction modules, a plurality of mixing mechanisms are arranged on the side faces of the adjacent microchannel reaction modules, a temperature control mechanism is arranged at the bottom of each microchannel reaction module, each microchannel reaction module comprises a shell, and a left pressing plate, a middle plate and a right pressing plate are arranged on the inner side of each shell. The left pressing plate, the middle plate and the right pressing plate are all connected with the shell, a first reaction area is arranged between the left pressing plate and the middle plate, and a second reaction area is arranged between the left pressing plate and the right pressing plate; the device has the advantages of being simple in structure, good in stability, good in mixing effect, high in temperature control stability and the like.

Description

Technical Field

[0001] The utility model belongs to the technical field of microchannel reactors, in particular to a microchannel reactor for pharmaceutical use. Background Art

[0002] Channel reactors are widely used in chemical reaction processes due to their efficient mass and heat transfer characteristics.

[0003] Traditional microchannel reactors have problems with poor mixing effect and insufficient temperature control stability during continuous production. Specifically, in traditional reactors, material mixing mainly depends on the channel design of the reactor itself, resulting in limited mixing effect, affecting the uniformity of the reaction and the quality of the product. At the same time, when adjusting the reaction temperature, the temperature control mechanism is often difficult to achieve rapid and accurate temperature control due to the small heat exchange area and low efficiency, which affects the stability of the reaction process and the yield of the product. Utility Model Content

[0004] The utility model aims to provide a microchannel reactor for pharmaceutical use in order to solve the problems of poor mixing effect and insufficient temperature control stability in common microchannel reactors.

[0005] The utility model achieves the above-mentioned purpose through the following technical solutions: it includes a plurality of microchannel reaction modules, a plurality of mixing mechanisms are arranged on the sides adjacent to the microchannel reaction modules, a temperature control mechanism is arranged at the bottom of the microchannel reaction module, the microchannel reaction module includes a shell, a left pressure plate, a middle plate and a right pressure plate are arranged on the inner side of the shell, the left pressure plate, the middle plate and the right pressure plate are all connected to the shell, a first reaction zone is arranged between the left pressure plate and the middle plate, and a second reaction zone is arranged between the left pressure plate and the right pressure plate.

[0006] Furthermore, the mixing mechanism includes a mixing chamber, both ends of the mixing chamber are fixedly connected to L-shaped flow chambers, one end of the L-shaped flow chamber is connected to the microchannel reaction module, a stirring screw rod is provided inside the mixing chamber, a stirring bent rod is provided inside the stirring screw rod, and connecting seats are provided at both ends of the stirring bent rod, and the connecting seat is connected to the stirring screw rod and the stirring bent rod by screws.

[0007] Furthermore, a servo motor is provided on one side of the L-shaped flow chamber and is connected by screws, a transmission rod is provided on the outer side of the connecting seat and is connected by screws, both of the transmission rods are connected to the mixing chamber through a rotating shaft, and one of the transmission rods passes through the mixing chamber and is connected to the output end of the servo motor.

[0008] Furthermore, the temperature control mechanism includes a medium input pipe and a medium output pipe, and the medium input pipe and the medium output pipe are connected by a plurality of U-shaped pipes. A pump is provided at one end of the medium input pipe and the medium output pipe and is connected thereto, and the other end of the medium input pipe and the medium output pipe are of closed design.

[0009] Furthermore, the U-shaped tube passes through the shell at the bottom, the U-shaped tube passes through the middle plate at the top, and the pipes on both sides of the U-shaped tube are respectively located in the first reaction zone and the second reaction zone.

[0010] Beneficial effects: The utility model has reasonable design and has the following beneficial effects:

[0011] 1. In the present invention, by providing a plurality of microchannel reaction modules and mixing mechanisms, the mixing efficiency between substances is effectively improved, and the uniformity of the reaction and the quality of the reaction products are ensured;

[0012] 2. In the solution of the utility model, the design of the stirring screw rod and the stirring curved rod in the mixing mechanism enables the reaction materials to be efficiently mixed in a smaller space, speeds up the mixing speed, reduces the reaction time, and thus significantly improves the production efficiency;

[0013] 3. In the present invention, the temperature control mechanism can realize precise control of the internal temperature of the reactor through the cooperation of several U-shaped tubes, thereby ensuring the consistency and stability of the reaction conditions, avoiding the problems of out-of-control reaction or unqualified products due to temperature fluctuations, and also improving the energy utilization efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a schematic diagram of the structure of the utility model;

[0015] Figure 2 It is an exploded view of the local structure of the utility model;

[0016] Figure 3 This is a cross-sectional view of the hybrid mechanism structure of the utility model;

[0017] Figure 4 This is a schematic diagram of the temperature control mechanism structure of the utility model;

[0018] Figure 5 It is a schematic diagram of the structure of local A of the utility model.

[0019] In the figure: 1-microchannel reaction module, 2-mixing mechanism, 3-temperature control mechanism;

[0020] 11-shell, 12-left pressure plate, 13-middle plate, 14-right pressure plate, 15-first reaction zone, 16-second reaction zone, 21-mixing chamber, 22-L-type flow chamber, 23-stirring screw rod, 24-stirring curved rod, 25-connecting seat, 26-servo motor, 27-transmission rod, 31-medium input pipe, 32-medium output pipe, 33-U-type pipe, 34-pump. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0022] Combination Figures 1 to 5 A pharmaceutical microchannel reactor is shown, comprising a plurality of microchannel reaction modules 1, a plurality of mixing mechanisms 2 are arranged on the sides of adjacent microchannel reaction modules 1, a temperature control mechanism 3 is arranged at the bottom of the microchannel reaction module 1, the microchannel reaction module 1 comprises a shell 11, a left pressure plate 12, a middle plate 13 and a right pressure plate 14 are arranged on the inner side of the shell 11, the left pressure plate 12, the middle plate 13 and the right pressure plate 14 are all connected to the shell 11, a first reaction zone 15 is arranged between the left pressure plate 12 and the middle plate 13, a second reaction zone 16 is arranged between the left pressure plate 12 and the right pressure plate 14, and an inlet and outlet are arranged through one side of the shell 11.

[0023] Among them, the mixing mechanism 2 includes a mixing chamber 21, both ends of the mixing chamber 21 are fixedly connected with an L-shaped flow chamber 22, one end of the L-shaped flow chamber 22 is connected to the microchannel reaction module 1, a stirring screw 23 is provided on the inner side of the mixing chamber 21, a stirring crank 24 is provided on the inner side of the stirring screw 23, and a connecting seat 25 is provided on both ends of the stirring crank 24. The connecting seat 25 is connected to the stirring screw 23 and the stirring crank 24 by screws. The material flows into the mixing chamber 21 through the L-shaped flow chamber 22, the stirring screw 23 stirs the material in a large range, and the stirring crank 24 stirs the material inside the stirring screw 23. The material fully mixed by the stirring screw 23 and the stirring crank 24 flows into the microchannel reaction module 1 to continue the reaction.

[0024] A servo motor 26 is provided on one side of the L-shaped flow chamber 22 and connected by screws. A transmission rod 27 is provided on the outer side of the connecting seat 25 and connected by screws. Both transmission rods 27 are connected to the mixing chamber 21 through a rotating shaft. One of the transmission rods 27 penetrates the mixing chamber 21 and is connected to the output end of the servo motor 26. The servo motor 26 drives the connecting seat 25 to rotate through the transmission rod 27, so that the stirring screw rod 23 and the stirring crank rod 24 rotate together to stir the material.

[0025] The temperature control mechanism 3 includes a medium input pipe 31 and a medium output pipe 32, and the medium input pipe 31 and the medium output pipe 32 are connected through a plurality of U-shaped pipes 33. A pump 34 is provided at one end of the medium input pipe 31 and the medium output pipe 32 and connected, and the other end of the medium input pipe 31 and the medium output pipe 32 is of a closed design. The temperature of the reaction area can be adjusted by arranging a plurality of U-shaped pipes 33 in the microchannel reaction module 1 to maintain the temperature stability of the entire reaction area, thereby avoiding the heat release or heat absorption generated by the material during the reaction affecting the temperature balance and causing a decrease in yield.

[0026] The U-shaped tube 33 passes through the shell 11 at the bottom, and the top of the U-shaped tube 33 passes through the middle plate 13. The pipes on both sides of the U-shaped tube 33 are respectively located in the first reaction zone 15 and the second reaction zone 16. The first reaction zone 15 and the second reaction zone 16 are divided into a plurality of areas by a plurality of U-shaped tubes 33, and each U-shaped tube 33 maintains the temperature steady state of a part of the area.

[0027] Working principle: When the utility model is in use, the material is sent into the microchannel reaction module 1 through the inlet for reaction, and then flows into the mixing chamber 21 through the L-shaped flow chamber 22. The stirring screw 23 stirs the material in a large range, and the stirring crank 24 stirs the material inside the stirring screw 23. The material fully mixed by the stirring screw 23 and the stirring crank 24 flows into another microchannel reaction module 1 to continue the reaction, and flows out from the outlet after the reaction is completed;

[0028] The temperature of the reaction area can be adjusted by a plurality of U-shaped tubes 33 arranged in the microchannel reaction module 1 to maintain the temperature of the entire reaction area stable, thereby preventing the temperature balance from being affected by the heat release or heat absorption generated by the materials during the reaction, resulting in a decrease in yield.

[0029] It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-restrictive from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.

[0030] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. A pharmaceutical microchannel reactor, comprising a plurality of microchannel reaction modules (1), characterized in that: A plurality of mixing mechanisms (2) are provided on the side of the adjacent microchannel reaction module (1); a temperature control mechanism (3) is provided on the bottom of the microchannel reaction module (1); the microchannel reaction module (1) comprises a shell (11); a left pressure plate (12), a middle plate (13) and a right pressure plate (14) are provided on the inner side of the shell (11); the left pressure plate (12), the middle plate (13) and the right pressure plate (14) are all connected to the shell (11); a first reaction zone (15) is provided between the left pressure plate (12) and the middle plate (13); and a second reaction zone (16) is provided between the left pressure plate (12) and the right pressure plate (14).

2. A pharmaceutical microchannel reactor according to claim 1, characterized in that: The mixing mechanism (2) comprises a mixing chamber (21), both ends of the mixing chamber (21) are fixedly connected to an L-shaped flow chamber (22), one end of the L-shaped flow chamber (22) is connected to the microchannel reaction module (1), a stirring screw rod (23) is provided inside the mixing chamber (21), a stirring crank rod (24) is provided inside the stirring screw rod (23), connecting seats (25) are provided at both ends of the stirring crank rod (24), and the connecting seat (25) is connected to the stirring screw rod (23) and the stirring crank rod (24) by screws.

3. A pharmaceutical microchannel reactor according to claim 2, characterized in that: A servo motor (26) is provided on one side of the L-shaped flow chamber (22) and is connected by screws. A transmission rod (27) is provided on the outer side of the connecting seat (25) and is connected by screws. Both of the transmission rods (27) are connected to the mixing chamber (21) via a rotating shaft. One of the transmission rods (27) passes through the mixing chamber (21) and is connected to the output end of the servo motor (26).

4. A pharmaceutical microchannel reactor according to claim 3, characterized in that: The temperature control mechanism (3) comprises a medium input pipe (31) and a medium output pipe (32), wherein the medium input pipe (31) and the medium output pipe (32) are connected to each other via a plurality of U-shaped pipes (33), a pump (34) is provided at one end of the medium input pipe (31) and the medium output pipe (32) and connected to each other, and the other ends of the medium input pipe (31) and the medium output pipe (32) are of closed design.

5. A pharmaceutical microchannel reactor according to claim 4, characterized in that: The U-shaped tube (33) passes through the shell (11) at the bottom, and the top of the U-shaped tube (33) passes through the middle plate (13). The pipes on both sides of the U-shaped tube (33) are respectively located in the first reaction zone (15) and the second reaction zone (16).

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