Lentivirus transportation device capable of accurately controlling temperature
By designing a precise temperature control system in the lentivirus transport device, using thermal oil and semiconductor refrigeration plates to achieve accurate control of the inner liner temperature, the problem of inaccurate temperature control of the existing devices is solved, and transportation convenience and practicality are improved.
Patent Information
- Application Number
- CN202421400259.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-19
- Publication Date
- 2025-03-07
- Estimated Expiration
- 2034-06-19
AI Technical Summary
The existing lentivirus transport devices lack precise temperature control structure and functions, and their transportation convenience and practicality need to be improved.
A lentivirus transport device with precise temperature control is designed, using the space between the inner liner and the inner wall of the transport box as the refrigeration chamber, which contains thermal oil, and real-time monitoring and precise control of the thermal oil temperature is achieved through semiconductor refrigeration plates and temperature controllers.
Accurate temperature control inside the inner liner is achieved, ensuring that the lentivirus reagent tube is in a low temperature environment, and improving the convenience and practicality of the transportation device.
Smart Images
Figure CN222573109U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of medical transportation, in particular to a lentivirus transportation device with precise temperature control. Background Art
[0002] Lentiviral vector is a gene therapy vector developed based on HIV-1 (human immunodeficiency virus type 1). Unlike general retroviral vectors, it has the ability to infect both dividing and non-dividing cells. Therefore, lentivirus is effectively used in the treatment of diseases. When in use, a transport device is required for transportation operations.
[0003] The existing transportation devices have a simple structure and lack precise temperature control structure and function. At the same time, the transportation convenience and practicality need to be improved. Utility Model Content
[0004] The purpose of the utility model is to provide a precise temperature-controlled lentivirus transport device that can perform precise temperature control operations and facilitate transportation.
[0005] To achieve the above objectives, the present invention provides the following technical solutions:
[0006] A precise temperature-controlled lentivirus transport device comprises a transport box, an inner liner is provided inside the transport box, the space between the inner liner and the inner wall of the transport box is set as a refrigeration chamber, the interior of the refrigeration chamber is filled with heat transfer oil, a mounting hole is provided on the side surface of the transport box, and a temperature sensor is fixedly installed inside the mounting hole, the detection end of the temperature sensor is placed inside the heat transfer oil, a temperature controller is fixedly installed on the outer surface of the transport box, the temperature sensor is electrically connected to the temperature controller, an installation window is provided on the side surface of the transport box, and a semiconductor refrigeration plate is installed inside the installation window, and the semiconductor refrigeration plate is electrically connected to the temperature controller.
[0007] By adopting the above technical solution, the temperature inside the inner tank can be effectively reduced, and the temperature of the heat transfer oil can be monitored in real time and accurately controlled.
[0008] Furthermore, a refrigerator is installed with a clip inside the installation window on the side surface of the transport box, and the refrigerator is attached to the cooling surface of the semiconductor refrigeration plate. A radiator is installed with a clip near the outer end of the installation window on the side surface of the transport box, and the radiator is attached to the heating surface of the semiconductor refrigeration plate.
[0009] By adopting the above technical solution, the temperature conduction of the semiconductor refrigeration plate can be effectively improved.
[0010] Furthermore, two supporting frames are fixedly connected to the inner wall of the liner, and a placement layer is snap-fitted onto the supporting frame. A plurality of insertion holes are provided on the outer surface of the placement layer, and rubber sleeves are adhered to the inner walls of the insertion holes by glue.
[0011] By adopting the above technical solution, it is convenient to disassemble and assemble the placement layer, and it is also convenient to insert the reagent tube into the socket of the placement layer.
[0012] Furthermore, two UV lamps are fixedly mounted on the symmetrical inner walls of the inner container.
[0013] By adopting the above technical solution, ultraviolet sterilization operation can be performed on the inside of the liner.
[0014] Furthermore, a stretching rod is fixedly installed on the side surface of the transport box, a shock absorber is fixedly installed at the four corner positions of the lower end surface of the transport box, one end of the shock absorber is fixedly connected to a support frame, and a universal wheel is rotatably installed at the four corner positions of the lower surface of the support frame.
[0015] By adopting the above technical solution, the device can be moved conveniently and the vibration transmitted by the road surface can be filtered at the same time.
[0016] Furthermore, a battery is fixedly installed at the middle position of the lower end surface of the transport box, and a box cover is hingedly connected to the edge position of the upper port of the transport box. The interior of the box cover is set as a hollow structure, and the interior of the hollow structure is filled with insulating gas. A handle is provided on the outer surface of the box cover.
[0017] By adopting the above technical solution, electric energy can be effectively provided to the electrical equipment on the transportation device.
[0018] In summary, the beneficial technical effects of the present invention are:
[0019] 1. The utility model can insert the reagent tube containing the lentivirus into the socket of the placement shelf, then use the semiconductor refrigeration plate to lower the temperature of the refrigerator, and then use the low-temperature refrigerator to cool the heat transfer oil inside the refrigeration chamber, thereby lowering the temperature inside the liner, so that the lentivirus inside the reagent tube can be kept in a low-temperature environment. At the same time, a temperature sensor is used to monitor the temperature of the heat transfer oil in real time, and the temperature data is transmitted to the temperature controller. The temperature controller is used to control the operation of the semiconductor refrigeration plate, so that the inside of the liner can be kept within a precise temperature range;
[0020] 2. The utility model can utilize universal wheels to facilitate the movement of the transport device. Since multiple shock absorbers are provided between the support frame and the transport box, the vibration transmitted by the bumpy road during the movement of the transport box can be effectively filtered out, thereby effectively improving the overall practicality.
[0021] 3. The utility model can remove the shelf for cleaning during use, and clean the inside of the liner at the same time. After cleaning, close the box cover, turn on the UV lamp, and use the UV lamp to perform ultraviolet sterilization on the inside of the liner. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;
[0023] Figure 2 This is a schematic diagram of the internal structure of the utility model;
[0024] Figure 3 For this utility model Figure 2 Enlarged view of point A.
[0025] In the figure: 1. Transport box; 2. Temperature controller; 3. Temperature sensor; 4. Inner liner; 5. Stretching rod; 6. Box cover; 7. Radiator; 8. Shelf placement; 9. Shock absorber; 10. Support frame; 11. Universal wheel; 12. Refrigeration chamber; 13. Battery; 14. UV lamp; 15. Semiconductor refrigeration plate; 16. Refrigerator. DETAILED DESCRIPTION
[0026] The method of the utility model is further described in detail below with reference to the accompanying drawings.
[0027] Refer to the attached Figure 1 , Attachment Figure 2 , Attachment Figure 3, a lentivirus transport device with precise temperature control, comprising a transport box 1, an inner liner 4 is provided inside the transport box 1, and the space between the inner liner 4 and the inner wall of the transport box 1 is set as a refrigeration chamber 12, the interior of the refrigeration chamber 12 is filled with heat transfer oil, a mounting hole is provided on the side surface of the transport box 1, and a temperature sensor 3 (PT100) is fixedly installed inside the mounting hole, the detection end of the temperature sensor 3 is placed inside the heat transfer oil, a temperature controller 2 is fixedly installed on the outer surface of the transport box 1, the temperature sensor 3 is electrically connected to the temperature controller 2, a mounting window is provided on the side surface of the transport box 1, and a semiconductor refrigeration plate 15 is installed inside the mounting window, the semiconductor refrigeration plate 15 is electrically connected to the temperature controller 2, a refrigerator 16 is installed inside the mounting window on the side surface of the transport box 1 with a snap-fit, the refrigerator 16 is attached to the cooling surface of the semiconductor refrigeration plate 15, a radiator 7 is mounted on the outer end of the mounting window on the side surface of the transport box 1 with a snap-fit, the radiator 7 is attached to the heating surface of the semiconductor refrigeration plate 15, and the middle position of the lower end surface of the transport box 1 is fixed A battery 13 is installed, and a box cover 6 is hingedly connected at the edge of the upper port of the transport box 1. The interior of the box cover 6 is set as a hollow structure, and the interior of the hollow structure is filled with heat-insulating gas. A handle is provided on the outer surface of the box cover 6. Two support frames are fixedly connected to the inner wall of the liner 4, and a placement shelf 8 is snap-fitted on the support frame. A plurality of sockets are provided on the outer surface of the placement shelf 8, and a rubber sleeve is glued to the inner wall of the socket by glue. The reagent tube containing the lentivirus can be inserted into the socket of the placement shelf 8, and then the semiconductor refrigeration plate 15 is used to reduce the temperature of the refrigerator 16, and then the low-temperature refrigerator 16 is used to cool the heat transfer oil inside the refrigeration chamber 12, thereby reducing the temperature inside the liner 4, so that the lentivirus inside the reagent tube can be in a low-temperature environment. At the same time, the temperature of the heat transfer oil is monitored in real time by the temperature sensor 3, and the temperature data is transmitted to the temperature controller 2. The temperature controller 2 controls the operation of the semiconductor refrigeration plate 15 so that the inside of the liner 4 can be within a precise temperature range.
[0028] Reference Figure 2 Two UV lamps 14 are fixedly installed on the symmetrical inner walls of the inner tank 4. During the intervals of use, the shelf 8 can be taken out for cleaning, and the inside of the inner tank 4 can be cleaned at the same time. After cleaning, the box cover 6 is buckled, the UV lamp 14 is turned on, and the UV lamp 14 is used to perform ultraviolet sterilization operation on the inside of the inner tank 4.
[0029] Reference Figure 1A stretching rod 5 is fixedly installed on the side surface of the transport box 1, and a shock absorber 9 is fixedly installed at the four corners of the lower end surface of the transport box 1. One end of the shock absorber 9 is fixedly connected to a support frame 10, and a universal wheel 11 is rotatably installed at the four corners of the lower surface of the support frame 10. The universal wheel 11 can be used to facilitate the movement of the transport device. Since multiple shock absorbers 9 are arranged between the support frame 10 and the transport box 1, the vibration transmitted by the bumps on the road during the movement of the transport box 1 can be effectively filtered, and the overall practicality is effectively improved.
[0030] Working principle: When in use, first insert the reagent tube containing the lentivirus into the socket of the placement layer 8, then snap the placement layer 8 onto the support frame of the inner tank 4, then close the box cover 6, and then start the semiconductor refrigeration plate 15, and use the semiconductor refrigeration plate 15 to reduce the temperature of the refrigerator 16, thereby reducing the temperature of the heat transfer oil inside the refrigeration chamber 12, thereby effectively reducing the temperature inside the inner tank 4, so that the lentivirus reagent tube can be in a low temperature state. At this time, the temperature sensor 3 is used to monitor the temperature of the heat transfer oil in real time, and the temperature data is transmitted to the temperature controller 2, and the temperature controller 2 is used to control the semiconductor refrigeration plate 1 5 works so that the inside of the liner 4 can be kept within a precise temperature range. When it needs to be mobile, stretch the stretching rod 5. At this time, the universal wheel 11 can be used to conveniently move the transport box 1. During transportation, since multiple shock absorbers 9 are provided between the support frame 10 and the transport box 1, the vibration transmitted by the bumps on the road during the movement of the transport box 1 can be effectively filtered. During the interval of the entire device, the placement layer 8 can be taken out for cleaning, and the inside of the liner 4 can be cleaned at the same time. After cleaning, buckle the box cover 6, turn on the UV lamp 14, and use the UV lamp 14 to perform ultraviolet sterilization operation on the inside of the liner 4.
[0031] The embodiments of this specific implementation method are all preferred embodiments of the present utility model, and are not intended to limit the scope of protection of the present utility model. Therefore, any equivalent changes made based on the structure, shape, and principle of the present utility model should be included in the scope of protection of the present utility model.
Claims
1. A precise temperature-controlled lentivirus transport device, comprising a transport box (1), characterized in that: The transport box (1) is provided with an inner liner (4) inside, the space between the inner liner (4) and the inner wall of the transport box (1) is provided as a refrigeration chamber (12), the interior of the refrigeration chamber (12) is filled with heat transfer oil, a mounting hole is provided on the side surface of the transport box (1), and a temperature sensor (3) is fixedly installed inside the mounting hole, the detection end of the temperature sensor (3) is placed inside the heat transfer oil, a temperature controller (2) is fixedly installed on the outer surface of the transport box (1), the temperature sensor (3) is electrically connected to the temperature controller (2), a mounting window is provided on the side surface of the transport box (1), and a semiconductor refrigeration plate (15) is installed inside the mounting window, and the semiconductor refrigeration plate (15) is electrically connected to the temperature controller (2).
2. The precise temperature-controlled lentivirus transport device according to claim 1, characterized in that: A refrigerator (16) is installed by snap-fitting inside the installation window on the side surface of the transport box (1), and the refrigerator (16) is attached to the cooling surface of the semiconductor refrigeration plate (15). A radiator (7) is installed by snap-fitting near the outer end of the installation window on the side surface of the transport box (1), and the radiator (7) is attached to the heating surface of the semiconductor refrigeration plate (15).
3. The precise temperature-controlled lentivirus transport device according to claim 1, characterized in that: Two supporting frames are fixedly connected to the inner wall of the inner liner (4), and a placement layer plate (8) is snap-fitted onto the supporting frame. A plurality of insertion holes are arranged on the outer surface of the placement layer plate (8), and rubber sleeves are glued to the inner walls of the insertion holes by glue.
4. The precise temperature-controlled lentivirus transport device according to claim 1, characterized in that: Two UV lamps (14) are fixedly mounted on the symmetrical inner walls of the inner container (4).
5. The precise temperature-controlled lentivirus transport device according to claim 1, characterized in that: A stretching rod (5) is fixedly mounted on the side surface of the transport box (1); a shock absorber (9) is fixedly mounted at each of the four corner positions of the lower end surface of the transport box (1); one end of the shock absorber (9) is fixedly connected to a support frame (10); and a universal wheel (11) is rotatably mounted at each of the four corner positions of the lower surface of the support frame (10).
6. The precise temperature-controlled lentivirus transport device according to claim 1, characterized in that: A storage battery (13) is fixedly mounted at the middle position of the lower end surface of the transport box (1); a box cover (6) is hingedly connected at the edge position of the upper end of the transport box (1); the interior of the box cover (6) is arranged as a hollow structure, and the interior of the hollow structure is filled with heat-insulating gas; and a handle is arranged on the outer surface of the box cover (6).