Sample collection device and sample preparation equipment
By designing a sample collection device, using the cooperation of the collection and transportation mechanism and the sample receiving mechanism, the automated registration, inspection and placement of samples is achieved, and the problem of time-consuming and labor-consuming sample processing in the prior art is solved, and the work efficiency is improved.
Patent Information
- Application Number
- CN202420005952.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-01-02
- Publication Date
- 2025-03-18
- Estimated Expiration
- 2034-01-02
AI Technical Summary
In the medical field, the samples to be tested need to be manually registered, inspected and placed, which leads to time-consuming and labor-intensive and lacks automated solutions.
A sample collection device is designed, including a collection and transportation mechanism, a sample receiving mechanism and a collection drive mechanism. The collection and transportation mechanism reciprocates in the first direction, and the transport bearing surface transmits the sample to the non-smooth receiving bearing surface with depressions and protrusions through the first handover position, realizing automatic transmission and placement of the sample.
Automatic registration, inspection and placement of samples is realized, work efficiency is improved, and time and energy for manual operation are reduced.
Smart Images

Figure CN222630271U_ABST
Abstract
Description
Technical Field
[0001] At least one embodiment of the present disclosure relates to a sample collection device and a sample preparation equipment. Background Art
[0002] In the medical field, the substances to be tested are usually placed in containers such as tubular containers. The tubular containers containing the substances to be tested are called samples. It is necessary to register the information of each sample, check whether the sample meets the requirements, and organize and arrange multiple samples in order to prepare for the test. Faced with a large number of samples to be tested, it is time-consuming and labor-intensive to manually register the information of the samples one by one, check whether the samples are qualified, and arrange the samples. Therefore, it is important to automatically perform these operations. Utility Model Content
[0003] At least one embodiment of the present disclosure provides a sample collection device, which includes: a collection and transportation mechanism, a sample receiving mechanism, and a collection driving mechanism. The collection and transportation mechanism is configured to reciprocate along a first direction, and includes a transportation carrying surface that intersects with the first direction and extends along a second direction as a whole, and the second direction is perpendicular to the first direction; the sample receiving mechanism has a receiving carrying surface that intersects with the first direction, and the receiving carrying surface extends along the second direction as a whole and is staggered with the transportation carrying surface in a third direction, and the third direction is perpendicular to both the first direction and the second direction; the collection driving mechanism is configured to drive the collection and transportation mechanism to reciprocate along the first direction to drive the transportation carrying surface to reciprocate along the first direction; the transportation carrying surface is configured to move along the first direction to a sampling position away from the receiving carrying surface to carry the sample, and is configured to move along the first direction to a first handover position close to the receiving carrying surface so that the sample carried on the transportation carrying surface moves to the receiving carrying surface, the height of the first handover position in the first direction is not lower than the height of the receiving carrying surface in the first direction and is adjacent to the receiving carrying surface in the third direction, and the receiving carrying surface is a non-smooth surface with depressions and protrusions.
[0004] For example, in the sample collection device provided by at least one embodiment of the present disclosure, the sample receiving mechanism includes a plurality of receiving bearing surfaces, which are respectively a first receiving bearing surface, a second receiving bearing surface, ..., and an Nth receiving bearing surface arranged in sequence from low to high in the first direction and staggered in the third direction, the heights of the plurality of receiving bearing surfaces in the first direction are different from each other and the positions are fixed, and N is a positive integer greater than 1; the collection and transportation mechanism includes a plurality of transportation bearing surfaces, which are respectively a first transportation bearing surface, a second transportation bearing surface, ..., and an Nth transportation bearing surface arranged in sequence from low to high in the first direction and staggered in the third direction; the first receiving bearing surface is located between the first transportation bearing surface and the second transportation bearing surface in the third direction; the first transportation bearing surface and the second transportation bearing surface are configured to move from low to high along the first direction at the same time to simultaneously reach the first handover position corresponding to the first receiving bearing surface and the second receiving bearing surface respectively, so that the sample carried on the first transportation bearing surface is transferred to the first receiving bearing surface, The sample carried on the second transport carrying surface is transferred to the second receiving carrying surface; the first transport carrying surface and the second transport carrying surface are configured to move from high to low simultaneously along the first direction to reach the sample initial supply position and the second handover position close to the first receiving carrying surface respectively at the same time, the height of the second handover position in the first direction is lower than the height of the first receiving carrying surface in the first direction and is adjacent to the first receiving carrying surface in the third direction, so that the sample at the sample initial supply position is carried to the first transport carrying surface and the sample carried on the first receiving carrying surface is carried to the second transport carrying surface, and when the second transport carrying surface moves from low to high along the first direction to the first handover position corresponding to the second receiving carrying surface, the sample carried on the second transport carrying surface is transferred to the second receiving carrying surface; the first handover position and the second handover position corresponding to the first receiving carrying surface are respectively located on the first side of the first receiving carrying surface away from the second receiving carrying surface and the second side close to the second receiving carrying surface in the third direction.
[0005] For example, in the sample collection device provided in at least one embodiment of the present disclosure, the collection and transportation mechanism includes a transportation plate extending along the first direction, the transportation plate includes a plurality of sub-transportation plates arranged in the first direction and staggered with each other in the third direction, the plurality of sub-transportation plates include a first sub-transportation plate and a second sub-transportation plate, the first sub-transportation plate has the first transportation bearing surface, and the second sub-transportation plate has the second transportation bearing surface; the sample receiving mechanism includes a receiving plate extending along the first direction, the receiving plate includes a plurality of sub-receiving plates arranged in the first direction and staggered with each other in the third direction, the plurality of sub-receiving plates include a first sub-receiving plate and a second sub-receiving plate, the first sub-receiving plate has the first receiving bearing surface, and the second sub-receiving plate has the second receiving bearing surface; the collection driving mechanism is configured to drive the first sub-transportation plate and The second sub-transport plate reciprocates along the first direction to make the first transport carrying surface and the second transport carrying surface reciprocate along the first direction; the second sub-transport plate is located between the first sub-receiving plate and the second sub-receiving plate in the third direction; when the first transport carrying surface is located at the first handover position and the sample carried on the first transport carrying surface is transferred to the first receiving carrying surface, the second sub-transport plate is configured to limit the sample located on the first receiving carrying surface so that the sample remains on the first receiving carrying surface; and, when the second transport carrying surface is located at the second handover position and the sample carried on the first receiving carrying surface is transferred to the second transport carrying surface, the second sub-receiving plate is configured to limit the sample located on the second receiving carrying surface so that the sample remains on the second receiving carrying surface.
[0006] For example, in the sample collection device provided by at least one embodiment of the present disclosure, for the first receiving carrying surface, when the first transport carrying surface is located at the first handover position, the surfaces of the first sub-transport plate and the first sub-receiving plate that are opposite to each other in the third direction are in contact with each other, or, there is a first interval between the first sub-transport plate and the first sub-receiving plate in the third direction, and the width of the first interval in the third direction is less than 1 / 2 of the width of the sample located on the first receiving carrying surface in the third direction; when the second transport carrying surface is located at the second handover position, the surfaces of the second sub-transport plate and the first sub-receiving plate that are opposite to each other in the third direction are in contact with each other, or, there is a second interval between the second sub-transport plate and the first sub-receiving plate in the third direction, and the width of the second interval in the third direction is less than 1 / 2 of the width of the sample located on the first receiving carrying surface in the third direction.
[0007] For example, in the sample collection device provided in at least one embodiment of the present disclosure, the height difference between the first receiving support surface and the second receiving support surface in the first direction is substantially equal to the height difference between the first transport support surface and the second transport support surface in the first direction.
[0008] For example, in the sample collection device provided by at least one embodiment of the present disclosure, the first transport carrying surface is a first inclined surface, the first inclined surface has a first edge close to the receiving carrying surface in the third direction and a second edge away from the receiving carrying surface, the height of the first edge of the first inclined surface in the first direction is less than the height of the second edge of the first inclined surface in the first direction, and the sample carried on the first inclined surface moves to the first receiving carrying surface along the direction from the second edge of the first inclined surface to the first edge of the first inclined surface; the second transport carrying surface is a second inclined surface and is basically parallel to the first transport carrying surface.
[0009] For example, in the sample collection device provided by at least one embodiment of the present disclosure, when the first transport supporting surface is located at the first intersection position, the height of the first edge of the first inclined surface in the first direction is substantially equal to the height of the first receiving supporting surface in the first direction, or the height of the first edge of the first inclined surface in the first direction is higher than the height of the first receiving supporting surface in the first direction.
[0010] For example, in the sample collection device provided in at least one embodiment of the present disclosure, the depressions and protrusions of the receiving support surface form a regular pattern or an irregular pattern.
[0011] For example, in the sample collection device provided in at least one embodiment of the present disclosure, the regular pattern includes at least one of a wave shape and a sawtooth shape.
[0012] For example, in the sample collection device provided in at least one embodiment of the present disclosure, the sample collection device is used to collect nucleic acid detection sampling tubes, and the samples are the nucleic acid detection sampling tubes; the length of each nucleic acid detection sampling tube located on each of the receiving bearing surfaces in the second direction is greater than its height in the first direction and greater than its width in the third direction, the size of each receiving bearing surface in the third direction is greater than or equal to 1 times the width of the nucleic acid detection sampling tube in the third direction and less than 2 times the width of the nucleic acid detection sampling tube in the third direction, and a plurality of nucleic acid detection sampling tubes are arranged in a single row along the second direction on each of the receiving bearing surfaces; the Nth receiving bearing surface is configured as a bearing surface of a movable conveyor belt, and the movable conveyor belt is configured to move along the second direction to transport the plurality of nucleic acid detection sampling tubes located on the bearing surface of the movable conveyor belt and arranged in a single row along the second direction.
[0013] For example, the sample collection device provided in at least one embodiment of the present disclosure further includes: a first blocking mechanism and a second blocking mechanism. The first blocking mechanism is located at the first end of each receiving bearing surface in the second direction, and is configured to block the sample located at the first end of each receiving bearing surface from sliding off; the second blocking mechanism is located at the second end of each receiving bearing surface in the second direction, and is configured to block the sample located at the second end of each receiving bearing surface from sliding off.
[0014] For example, in the sample collection device provided in at least one embodiment of the present disclosure, the sample has three dimensions of length, width and height in three directions perpendicular to each other, and the length is greater than the width and greater than the height; when the sample is located on the receiving support surface, the sample has a horizontal state and a vertical state; in the horizontal state, the length of the sample is along the second direction; in the vertical state, the length of the sample is along the first direction; the sample collection device also includes: a sensor and an injection mechanism. The sensor is arranged at a sensing position on at least one of the first blocking mechanism and the second blocking mechanism, and is configured to sense a sample located at the first end and / or the second end of the receiving support surface corresponding to at least one of the first blocking mechanism and the second blocking mechanism and at a position substantially the same as the height of the sensing position, wherein the height of the sensing position is the height of the sensing position relative to the receiving support surface corresponding to at least one of the first blocking mechanism and the second blocking mechanism in the first direction, and the value of the height of the sensing position is greater than the value of the width of the sample and greater than the value of the height of the sample and less than the value of the length of the sample; the injection mechanism is arranged on at least one of the first blocking mechanism and the second blocking mechanism, and is configured to: when the sensor senses that the sample exists at the first end and / or the second end corresponding to the receiving support surface and at a position substantially the same as the height of the sensing position, inject a force-applying substance toward the sample to apply a force to the sample at a position substantially the same as the height of the sensing position to knock the sample down onto the corresponding receiving support surface so that the sample is in the horizontal state.
[0015] For example, in the sample collection device provided in at least one embodiment of the present disclosure, the force-applying substance is compressed air.
[0016] At least one embodiment of the present disclosure further provides a sample preparation device, which includes the sample collection device provided in an embodiment of the present disclosure and a sample transport device connected to the sample collection device, wherein the sample transport device is configured to transport the sample from the sample collection device.
[0017] The sample collection device provided by the embodiment of the present disclosure can be used to collect, for example, tubular samples containing substances to be detected, for example, the tubular samples are nucleic acid detection samples. The sample is collected on the transport bearing surface, and the transport bearing surface moves along the first direction so that when the transport bearing surface reaches the first intersection position close to the receiving bearing surface, the sample moves to the receiving bearing surface, thereby realizing the transfer of the sample along the first direction. At the same time, since the receiving bearing surface is a non-smooth surface with depressions and protrusions, the sample on the receiving bearing surface will not be able to maintain an upright state due to unbalanced force, but will be in a horizontal state. Multiple test tubes are arranged along the second direction to facilitate the orderliness of subsequent transportation, and facilitate the subsequent automatic counting and information collection of multiple samples one by one. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings of the embodiments will be briefly introduced below. Obviously, the drawings in the following description only relate to some embodiments of the present utility model, rather than limiting the present utility model.
[0019] Figure 1 is a schematic diagram of a sample collection device provided by an embodiment of the present disclosure;
[0020] Figure 2 is a specific structural schematic diagram of a sample collection device provided by an embodiment of the present disclosure;
[0021] Figure 3A is a partially enlarged schematic diagram of a sample collection device provided by an embodiment of the present disclosure in working state 1;
[0022] Figure 3B is a partially enlarged schematic diagram of a sample collection device provided by an embodiment of the present disclosure in working state 2;
[0023] Figure 4 is a partial schematic diagram of a sample collection device including a sensor and an injection mechanism provided by an embodiment of the present disclosure;
[0024] Figure 5 yes Figure 4 A schematic diagram of the operation of the sensor and the injection mechanism;
[0025] Figure 6 It is a schematic diagram of a sample preparation device provided in one embodiment of the present disclosure. DETAILED DESCRIPTION
[0026] In order to make the purpose, technical solution and advantages of the embodiment of the utility model clearer, the technical solution of the embodiment of the utility model will be clearly and completely described below in conjunction with the drawings of the embodiment of the utility model. Obviously, the described embodiment is a part of the embodiment of the utility model, not all of the embodiments. Based on the described embodiment of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0027] Unless otherwise defined, the technical or scientific terms used herein shall have the usual meanings understood by persons with ordinary skills in the field to which the utility model belongs. The words "first", "second" and similar words used in the patent application specification and claims of the utility model do not indicate any order, quantity or importance, but are only used to distinguish different components. Words such as "include" or "comprise" mean that the elements or objects appearing before the word include the elements or objects listed after the word and their equivalents, without excluding other elements or objects. "Inside", "outside" and the like are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may also change accordingly.
[0028] The dimensions of the drawings used in this disclosure are not drawn strictly according to the actual scale, and the specific dimensions and quantities of each structure can be determined according to actual needs. The drawings described in this disclosure are only schematic diagrams of the structures.
[0029] Before automatically executing steps such as registering information on samples one by one and checking whether the samples are qualified, it is first necessary to automatically collect the products one by one and transmit them to the information collection area.
[0030] At least one embodiment of the present disclosure provides a sample collection device, which includes: a collection and transportation mechanism, a sample receiving mechanism, and a collection drive mechanism. The collection and transportation mechanism is configured to reciprocate along a first direction, and includes a transportation bearing surface intersecting the first direction and extending along a second direction as a whole, the second direction being perpendicular to the first direction; the sample receiving mechanism has a receiving bearing surface intersecting the first direction, the receiving bearing surface is staggered with the transportation bearing surface in a third direction, the third direction being perpendicular to both the first direction and the second direction; the collection drive mechanism is configured to drive the collection and transportation mechanism to reciprocate along the first direction to drive the transportation bearing surface to reciprocate along the first direction; the transportation bearing surface is configured to move along the first direction to a sampling position away from the receiving bearing surface to carry the sample, and is configured to move along the first direction to a first intersection position close to the receiving bearing surface so that the sample carried on the transportation bearing surface moves to the receiving bearing surface, the height of the first intersection position in the first direction is not lower than the height of the receiving bearing surface in the first direction and is adjacent to the receiving bearing surface in the third direction, and the receiving bearing surface is a non-smooth surface with depressions and protrusions.
[0031] The sample collection device provided by the embodiment of the present disclosure can be used to collect, for example, tubular samples containing substances to be detected. The samples are collected onto the transport bearing surface. The transport bearing surface moves along the first direction so that when the transport bearing surface reaches the first intersection position close to the receiving bearing surface, the sample moves along the inclined surface inclined toward the receiving bearing surface to the receiving bearing surface, thereby realizing the transfer of the sample along the first direction. At the same time, since the receiving bearing surface is a non-smooth surface with depressions and protrusions, the sample on the receiving bearing surface cannot maintain an upright state due to unbalanced force, but will be in a horizontal state. The sample in the horizontal state has the largest size in the second direction, and the height in the first direction is less than its size in the second direction. For example, when the sample is a test tube sample, the test tube will not be in an upright state on the receiving bearing surface, but the extension direction of the columnar test tube is consistent with the second direction, that is, the test tube is in a horizontal state, and multiple test tubes are arranged along the second direction to facilitate the orderliness of subsequent transportation and facilitate the subsequent automatic counting and information collection of multiple samples one by one.
[0032] At least one embodiment of the present disclosure further provides a sample preparation device, which includes the sample collection device provided in an embodiment of the present disclosure and a sample transport device connected to the sample collection device, wherein the sample transport device is configured to transport the sample from the sample collection device.
[0033] It should be noted that the “height in the first direction” in the present disclosure refers to the height relative to the ground in the first direction.
[0034] The transport bearing surface extends along the second direction as a whole, which means that the extension trend of the transport bearing surface is along the first direction, for example, the transport bearing surface may be a straight line extending along the second direction, or the transport bearing surface may be bent or inclined relative to the second direction, but the direction from the starting end to the ending end of the transport bearing surface is along the second direction. The same is true for the receiving bearing surface extending along the second direction as a whole.
[0035] For example, Figure 1 Schematic diagram of a sample collection device provided by an embodiment of the present disclosure. Figure 1-2At least one embodiment of the present disclosure provides a sample collection device 10, which includes: a collection and transportation mechanism 1, a sample receiving mechanism 2, and a collection driving mechanism 5. The collection and transportation mechanism 2 is configured to reciprocate along a first direction D1, and includes a transportation bearing surface (taking the first transportation bearing surface 4a as an example) intersecting the first direction D1 and extending along a second direction D2 as a whole, and the second direction D2 is perpendicular to the first direction D1; the sample receiving mechanism 1 has a receiving bearing surface (taking the first receiving bearing surface 3a as an example) intersecting the first direction D1, and the receiving bearing surface extends along the second direction D2 as a whole and is staggered with the transportation bearing surface in a third direction D3, and the third direction D3 is perpendicular to both the first direction D1 and the second direction D2, that is, the orthographic projections of the receiving bearing surface and the transportation bearing surface on the surface perpendicular to the first direction D1 do not overlap. The collection drive mechanism 5 is configured to drive the collection and transportation mechanism 1 to reciprocate along the first direction D1 to drive the transportation bearing surface to reciprocate along the first direction D1, and the transportation bearing surface is configured to move downward (e.g., toward the ground) along the first direction D1 to a sampling position away from the receiving bearing surface to carry the sample 6, and is configured to move upward (e.g., away from the ground) along the first direction D1 to a first intersection position close to the receiving bearing surface so that the sample 6 carried on the transportation bearing surface is transferred to the receiving bearing surface, and the height of the first intersection position in the first direction D1 is not lower than the height of the receiving bearing surface in the first direction D1 and is adjacent to the receiving bearing surface in the third direction D3, and the receiving bearing surface is a non-smooth surface with depressions and protrusions. The sample collection device provided in the embodiment of the present disclosure can be used to collect, for example, a tubular sample containing a substance to be detected. For example, the sample collection device 10 is used to collect tubular samples, for example, the tubular sample is a nucleic acid detection sampling tube, and the sampling tube contains a substance to be detected taken from a test individual (e.g., a human body). The sample is collected onto the transport carrying surface, and the transport carrying surface moves along the first direction so that when the transport carrying surface reaches the first intersection position close to the receiving carrying surface, the sample moves toward the receiving carrying surface at a speed along the third direction D3 to be transferred to the receiving carrying surface, thereby realizing the collection and transfer of the sample along the first direction D1. At the same time, since the receiving carrying surface is a non-smooth surface with depressions and protrusions, the sample on the receiving carrying surface will not be able to maintain a vertical state due to unbalanced force, but will be in a horizontal state. The sample in the horizontal state has the largest size in the second direction, and the height in the first direction is smaller than its size in the second direction. For example, when the sample is a test tube sample, the test tube will not be in a vertical state on the receiving carrying surface, but the extension direction of the columnar test tube is consistent with the second direction, that is, the test tube is in a horizontal state, and multiple test tubes are arranged along the second direction to facilitate the orderliness of subsequent transportation and facilitate the subsequent automatic counting and one-by-one information collection of multiple samples.
[0036] Here we explain the horizontal and vertical states of the sample. Figure 4Sample 6 has three dimensions of length d1, width d2 and height (not marked) in three mutually perpendicular directions. For example, the length d1 of sample 6 is greater than the width d2 of sample 6 and greater than the height of sample 6; when sample 6 is located on the first receiving support surface 3a, sample 6 has a horizontal state (such as sample No. 1 61) and a vertical state (such as sample No. 2); in the horizontal state, such as sample No. 1 61, the length d1 of sample No. 1 61 is along the second direction D2; in the vertical state, such as sample No. 2, the length d1 of sample No. 2 62 is along the first direction D1.
[0037] refer to Figure 2The sample receiving mechanism 2 includes a plurality of receiving bearing surfaces, which are respectively arranged in sequence from low to high in the first direction D1 (direction 1 in the figure) and staggered in the third direction D3, a first receiving bearing surface 3a, a second receiving bearing surface 3b, ..., an Nth receiving bearing surface, the heights of the plurality of receiving bearing surfaces in the first direction D1 are different from each other and the positions are fixed, and N is a positive integer greater than 1; the collection and transportation mechanism 1 includes a plurality of transportation bearing surfaces, which are respectively arranged in sequence from low to high in the first direction D1 (direction 1 in the figure) and staggered in the third direction D3. The first transport carrying surface 4a, the second transport carrying surface 4b, ..., the Nth transport carrying surface are separated; the first receiving carrying surface 3a is located between the first transport carrying surface 4a and the second transport carrying surface 4b in the third direction D3; the first transport carrying surface 4a and the second transport carrying surface 4b are configured to move from low to high along the first direction D1 (direction 1 in the figure) at the same time to reach the first connecting position corresponding to the first receiving carrying surface 3a and the second receiving carrying surface 3b at the same time, so that the sample carried on the first transport carrying surface 4a is transferred to the first receiving carrying surface 3a, and the second transport carrying surface 4b is transferred to the first receiving carrying surface 3a. The sample carried on the carrying surface 4b is transferred to the second receiving carrying surface 3b; the first transport carrying surface 4a and the second transport carrying surface 4b are configured to move simultaneously from high to low (direction 2 in the figure) along the first direction D1 to simultaneously reach the sample initial supply position P0 and the second intersection position close to the first receiving carrying surface 3a, respectively, the height of the second intersection position in the first direction D1 is lower than the height of the first receiving carrying surface 3a in the first direction D1 and is adjacent to the first receiving carrying surface 3a in the third direction D3, so that the sample at the sample initial supply position P0 is carried to the first transport carrying surface 4a and the second intersection position is adjacent to the first receiving carrying surface 3a in the third direction D3. The sample carried on the first receiving carrying surface 4a and the first receiving carrying surface 3a is carried on the second transport carrying surface 4b, and when the second transport carrying surface 4b moves from low to high along the first direction D1 to the first intersection position corresponding to the second receiving carrying surface 3b, the sample carried on the second transport carrying surface 4b is transferred to the second receiving carrying surface 3b; the first intersection position and the second intersection position corresponding to the first receiving carrying surface 3a are respectively located on the first side of the first receiving carrying surface 3a away from the second receiving carrying surface 3b and the second side close to the second receiving carrying surface 3b in the third direction D3. For example, the first transport carrying surface 4a and the second transport carrying surface 4b move from low to high along the first direction D1 at the same time or move from high to low along the first direction D1 at the same time. In this way, the first transport carrying surface 4a and the second transport carrying surface 4b reciprocate in the first direction D1, while the first receiving carrying surface 3a and the second receiving carrying surface 3b remain fixed in position, so as to transfer the sample from low to high in the first direction D1 to the second receiving carrying surface 3b with a higher position, and to transfer the sample from low to high along the first direction while keeping the sample in a horizontal state on the second receiving carrying surface 3b.
[0038] For example, N is greater than 2, and the adjacent receiving carrying surfaces and the adjacent transport carrying surfaces in the first direction D1 work like the above-mentioned cooperation between the first receiving carrying surface 3a and the second receiving carrying surface 3b and the first transport carrying surface 4a and the second transport carrying surface 4b to achieve the step-by-step transfer of the sample along the first direction, thereby ensuring the reliability of the sample transfer along the first direction and adapting to a relatively large transfer distance.
[0039] For example, refer to Figure 2 The collection and transportation mechanism 1 includes a transportation plate extending along a first direction D1, the transportation plate includes a plurality of sub-transportation plates arranged in the first direction D1 and staggered in a third direction D3, the plurality of sub-transportation plates include a first sub-transportation plate 11 and a second sub-transportation plate 12, the first sub-transportation plate 11 has a first transportation bearing surface 4a, and the second sub-transportation plate 12 has a second transportation bearing surface 4b; the sample receiving mechanism 2 includes a receiving plate extending along the first direction D1, the receiving plate includes a plurality of sub-receiving plates arranged in the first direction D1 and staggered in the third direction D3, the plurality of sub-receiving plates include a first sub-receiving plate 21 and a second sub-receiving plate 22, the first sub-receiving plate 21 has a first receiving bearing surface 3a, and the second sub-receiving plate 22 has a second receiving bearing surface 3b; the collection driving mechanism 5 is configured to drive the first sub-transportation plate 11 and the second sub-transportation plate 12 to reciprocate along the first direction D1 so that the first transportation bearing surface 4a and the second transportation bearing surface 4b reciprocate along the first direction D1; refer to Figure 3B , the second sub-transportation plate 12 is located between the first sub-receiving plate 21 and the second sub-receiving plate 22 in the third direction D3. Figure 2 3B is a schematic diagram of a sample collection device 10 in working state 1 provided by an embodiment of the present disclosure, and 3B is a partially enlarged schematic diagram of a sample collection device 10 in working state 2 provided by an embodiment of the present disclosure, Figure 2 The first sub-transport plate 11 and the second sub-transport plate 12 in the sample collecting device 10 move downward along the first direction D1 so that the sample collecting device 10 is switched from the working state 1 to the working state 2. Figure 3B In the working state 2 shown, at this time, the side surface of the first sub-receiving plate 21 intersecting with the first receiving bearing surface 3a and the side surface of the second sub-receiving plate 22 intersecting with the second receiving bearing surface 3b are exposed.
[0040] Figure 3A is a partially enlarged schematic diagram of a sample collection device 10 provided by an embodiment of the present disclosure in working state 1; Figure 3B FIG. 1 is a partially enlarged schematic diagram of a sample collection device 10 in working state 2 provided by an embodiment of the present disclosure. When the sample collection device 10 is working, the first sub-transport plate 11 and the second sub-transport plate 12 can reciprocate along the first direction D1 to reach different positions, thereby switching between working state 1 and working state 2. Figure 3AAs shown, when the first transport carrying surface 4a is located at the first handover position and the sample 6 carried on the first transport carrying surface 4a is transferred to the first receiving carrying surface 3a, Figure 3A The position where the first transport bearing surface 4a is located is the first handover position, and the second sub-transport plate 12 is configured to limit the sample 6 located on the first receiving bearing surface 3a so that the sample 6 remains on the first receiving bearing surface 3a, that is, the second sub-transport plate 12 can prevent the sample 6 on the first receiving bearing surface 3a from sliding down in the third direction D3. Figure 3B As shown, when the second transport carrying surface 4b is located at the second handover position and the sample 6 carried on the first receiving carrying surface 3a is transferred to the second transport carrying surface 4b, Figure 3B The position of the second transport bearing surface 4b is the second intersection position, and the second sub-receiving plate 22 is configured to limit the sample 6 located on the second receiving bearing surface 3b so that the sample remains on the second receiving bearing surface 3b, that is, the second sub-receiving plate 22 can prevent the sample 6 on the second receiving bearing surface 3b from sliding down in the third direction D3. In this way, through the positional relationship between the first sub-transport plate 11, the second sub-transport plate 12 and the first sub-receiving plate 21 and the second sub-receiving plate 22 and the reciprocating motion of the first sub-transport plate 11 and the second sub-transport plate 12 along the first direction D1, the sample is stably transferred from low to high in the first direction D1 to the receiving bearing surface at a higher level, and the sample is stably kept in a horizontal state on each level of the receiving bearing surface.
[0041] like Figure 3A As shown, for the first receiving bearing surface 3a, when the first transport bearing surface is located at the first handover position, the surfaces of the first sub-transport plate 11 and the first sub-receiving plate 21 facing each other in the third direction D3 are attached to each other, that is, there is no gap between them. Alternatively, in other embodiments, there is a first interval between the first sub-transport plate 11 and the first sub-receiving plate 21 in the third direction D3, and the width of the first interval in the third direction D3 is less than 1 / 2 of the width of a sample 6 located on the first receiving bearing surface 3a in the third direction D3, so as to prevent the sample 6 from sliding into the first interval. When the second transport bearing surface is located at the second handover position, the surfaces of the second sub-transport plate 12 and the first sub-receiving plate 21 facing each other in the third direction D3 are attached to each other. Alternatively, in other embodiments, there is a second interval between the second sub-transport plate 12 and the first sub-receiving plate 21 in the third direction D3, and the width of the second interval in the third direction D3 is less than 1 / 2 of the width of the sample located on the first receiving bearing surface 3a in the third direction D3, so as to prevent the sample 6 from sliding into the second interval.
[0042] refer to Figure 2The height difference between the first receiving bearing surface 3a and the second receiving bearing surface 3b in the first direction D1 is substantially equal to the height difference between the first transport bearing surface 4a and the second transport bearing surface 4b in the first direction D1, so that the first transport bearing surface 4a and the second transport bearing surface 4b with the height difference can simultaneously reciprocate along the first direction D1 to cooperate with the positions of the first receiving bearing surface 3a and the second receiving bearing surface 3b with the same height difference to reach the accurate first handover position and the second handover position, thereby reducing the difficulty of the collection driving mechanism 5 to drive the first sub-transport plate 11 and the second sub-transport plate 12 to move.
[0043] For example, the driving mechanism 5 includes a motor and a crank-connecting rod mechanism connected to an electrode, the connecting rod of the crank-connecting rod mechanism extends along the first direction D1 and is connected to a plurality of sub-transportation plates, such as the first sub-transportation plate 11 and the second sub-transportation plate 12, and the crank-connecting rod mechanism is driven by the motor to drive the plurality of sub-transportation plates including the first sub-transportation plate 11 and the second sub-transportation plate 12 to reciprocate along the first direction D1. Of course, this design is not limited to this design, as long as it can achieve the reciprocating movement of the plurality of sub-transportation plates including the first sub-transportation plate 11 and the second sub-transportation plate 12 along the first direction D1. The movements of the plurality of sub-transportation plates can be independent or coupled, and can be designed according to needs.
[0044] For example, the transport supporting surface is an inclined surface inclined toward the receiving supporting surface. Compared with a case where the transport supporting surface is a horizontal surface (i.e., the first side and the second side of the transport supporting surface and the entire surface are equal in height in the first direction), when the transport supporting surface reaches the first intersection position close to the receiving supporting surface, the sample can move more smoothly along the inclined surface inclined toward the receiving supporting surface to the receiving supporting surface.
[0045] The transport bearing surface is an inclined surface inclined toward the receiving bearing surface, which means that: in the third direction D3, the transport bearing surface has a first edge close to the receiving bearing surface and a second edge away from the receiving bearing surface, and the height of the first edge of the transport bearing surface in the first direction D1 is less than the height of the second edge of the transport bearing surface in the first direction D1.
[0046] Figure 5 yes Figure 4 Schematic diagram of the working of the sensor and injection mechanism. Figure 2 and Figure 5For example, the first transport bearing surface 4a is a first inclined surface, and the first inclined surface has a first edge 4a-1 close to the first receiving bearing surface and a second edge 4a-2 away from the first receiving bearing surface in the third direction D3. The height of the first edge 4a-1 of the first inclined surface in the first direction D1 is less than the height of the second edge 4a-2 of the first inclined surface in the first direction D1, that is, the first transport bearing surface 4a is an inclined surface inclined toward the first receiving bearing surface 3a. In this way, when the first inclined surface reaches the corresponding first junction position, the sample 6 on the first inclined surface can be smoothly made to slide along the first inclined surface to the first receiving bearing surface 3a adjacent to the first inclined surface under the action of unbalanced force, that is, the sample 6 carried on the first inclined surface moves to the first receiving bearing surface 3a along the direction from the second edge 4a-2 of the first inclined surface to the first edge 4a-1 of the first inclined surface. Similarly, the second transport carrying surface 4b is a second inclined surface and is basically parallel to the first transport carrying surface 4a, that is, the second inclined surface has a first edge close to the second receiving carrying surface 3b and a second edge away from the second receiving carrying surface 3b in the third direction D3, and the height of the first edge of the second inclined surface in the first direction D1 is less than the height of the second edge of the second inclined surface in the first direction D1, that is, the second transport carrying surface 4b is an inclined surface inclined toward the second receiving carrying surface 3b, so that when the second inclined surface reaches the corresponding first junction position, the sample on the second inclined surface can be smoothly made to slide along the second inclined surface to the second receiving carrying surface adjacent to the second inclined surface under the action of unbalanced force.
[0047] For the first receiving bearing surface 3a, Figure 3A As shown, the height of the first transport carrying surface 4a at the first intersection in the first direction D1 is substantially the same as the height of the first receiving carrying surface 3a in the first direction D1, so that the sample on the first transport carrying surface 4a can be stably transferred to the first receiving carrying surface 3a. Figure 3A When the first transport bearing surface 4a is located at the first intersection position, the height of the first edge 4a-1 of the first inclined surface in the first direction D1 is substantially equal to the height of the first receiving bearing surface 3a in the first direction D1.
[0048] For example, Figure 3B As shown, for the first receiving carrying surface 3a, the height of the second transport carrying surface 4b at the second intersection position in the first direction D1 is lower than the height of the first receiving carrying surface 3a in the first direction D1. For example, the height of the second transport carrying surface 4b is basically the same as the height of the first receiving carrying surface 3a but slightly lower than the height of the first receiving carrying surface 3a, so as to ensure that the sample on the first receiving carrying surface 3a can be smoothly moved to the second transport carrying surface 4b at a speed along the third direction D1 and under the action of gravity, thereby ensuring the success rate of sample transmission and improving the collection efficiency of the sample collection device.
[0049] Alternatively, in other embodiments, for the first receiving carrying surface, the height of the first transport carrying surface at the first intersection position in the first direction D1 is higher than the height of the first receiving carrying surface in the first direction D1, and the sample on the first transport carrying surface can also be stably transferred to the first receiving carrying surface. For example, the height of the first side of the first inclined surface in the first direction D1 is higher than the height of the first receiving carrying surface in the first direction D1.
[0050] Alternatively, in other embodiments, for the first receiving carrying surface, the height of the second transport carrying surface at the second junction position in the first direction D1 is equal to the height of the first receiving carrying surface in the first direction D1, and the sample on the first receiving carrying surface can be moved to the second transport carrying surface at a speed along the third direction D1.
[0051] refer to Figure 5 For example, for each receiving bearing surface, the depressions 31 and protrusions 32 of the receiving bearing surface form a regular pattern or an irregular pattern. For example, the regular pattern includes at least one of a wave shape and a sawtooth shape. The regular pattern can make the state of the entire receiving bearing surface for the carried sample relatively uniform and stable, which is conducive to controlling the working efficiency of the sample collection device. For example, the depressions and protrusions can be arranged periodically. Of course, in some embodiments, the depressions and protrusions can also be irregular. For example, the surfaces of the depressions 31 and the protrusions 32 can be curved surfaces or planes, respectively.
[0052] It should be noted that the depressions and protrusions described in the embodiments of the present disclosure refer to depressions and protrusions visible to the naked eye, and refer to macroscopic depressions and protrusions rather than microscopic depressions and protrusions indicating surface roughness.
[0053] For example, the planar pattern of each transport carrying surface is a bar extending along the second direction D2, such as a straight bar, and the planar pattern of each receiving carrying surface is a bar extending along the second direction D2, such as a straight bar, so as to facilitate stable carrying of multiple samples arranged along the second direction D2.
[0054] For example, the length of the bar-shaped transport bearing surface along the second direction D2 is substantially equal to the length of the bar-shaped receiving bearing surface along the second direction D2, so that the lengths of the two can match at the first intersection position and the second intersection position, which is conducive to the stable transmission of multiple samples.
[0055] For example, the length of the strip-shaped transport bearing surface along the second direction D2 is much greater than its width along the third direction, for example, the length of the strip-shaped transport bearing surface along the second direction D2 is greater than 10 times its width along the third direction. Correspondingly, the length of the strip-shaped receiving bearing surface along the second direction D2 is much greater than its width along the third direction, for example, the length of the strip-shaped receiving bearing surface along the second direction D2 is greater than 10 times its width along the third direction.
[0056] For example, the sample collection device 10 is used to collect nucleic acid detection sampling tubes, and the samples are nucleic acid detection sampling tubes; the length of each nucleic acid detection sampling tube located on each receiving bearing surface in the second direction D2 is greater than its height in the first direction D1 and greater than its width in the third direction D3, and the size of each receiving bearing surface in the third direction D3 is greater than or equal to 1 times the width of the nucleic acid detection sampling tube in the third direction D3 and less than 2 times the width of the nucleic acid detection sampling tube in the third direction D3, so that multiple nucleic acid detection sampling tubes are arranged in a single row on each receiving bearing surface along the second direction D2; the Nth receiving bearing surface is configured as a bearing surface of a movable conveyor belt, and the movable conveyor belt is configured to move along the second direction D2 to transmit multiple nucleic acid detection sampling tubes arranged in a single row on the bearing surface of the movable conveyor belt along the second direction D2. The multiple nucleic acid detection sampling tubes arranged in a single row can be directly transported to the subsequent link by the movable conveyor belt, which is convenient for transporting to the subsequent link to count the multiple sampling tubes, collect information of the sampling tubes one by one, and check whether they meet the requirements, such as whether they are empty tubes, whether they are leaking, etc.
[0057] Multiple collection tubular samples 6 are arranged in a single row along the second direction D2 on each receiving support surface, and the length d1 of each nucleic acid detection sampling tube in the second direction D2 is greater than its height in the first direction D1 and greater than its width d2 in the third direction D3.
[0058] For example, refer to Figure 4 The sample collection device 10 further includes a first blocking mechanism 7a and a second blocking mechanism 7b. The first blocking mechanism 7a is located at the first end of each receiving bearing surface in the second direction D2, and is configured to block the sample located at the first end of each receiving bearing surface from sliding off; the second blocking mechanism 7b is located at the second end of each receiving bearing surface in the second direction D2, and is configured to block the sample located at the second end of each receiving bearing surface from sliding off.
[0059] For example, the sample collection device 10 further includes a sensor and an injection mechanism. Figure 4-5, the sensor includes a first sensor 1a, and the ejection mechanism includes a first ejection mechanism 2a. The first sensor 1a is disposed at a first sensing position on the first blocking mechanism 7a, and is configured to sense a sample located at a first end of a receiving bearing surface corresponding to the first blocking mechanism 7a and at a position substantially the same height as the first sensing position, such as sample No. 2 62 in a vertical state, the height of the first sensing position being the height of the first sensing position relative to the receiving bearing surface corresponding to the first blocking mechanism 7a in the first direction D1, and the value of the height of the first sensing position being greater than the value of the width of the sample 6 and greater than the value of the height of the sample 6 and less than the value of the length d1 of the sample; for example, the tube body of the sample 6 is cylindrical, and the height of the sample 6 is equal to the width d2 of the sample 6; for example, the height and width of the sample 6 here refer to the maximum height of the sample 6 in the height direction and the maximum width in the width direction, because the height and width of the sample 6 at various positions may not be equal. For example, the first spraying mechanism 2a is arranged on the first blocking mechanism 7a and is configured as follows: when the first sensor 1a senses the presence of a sample at the first end of the corresponding receiving support surface and at a position substantially the same height as the first sensing position, a force-applying substance is sprayed toward the sample to apply force to the sample at a position substantially the same height as the first sensing position to knock the sample down onto the corresponding receiving support surface so that the sample is in a horizontal state. After multiple samples 6 are transferred to the first receiving support surface 3a, a corner is formed between the inner side surface 71 of the first blocking mechanism 7a facing the first receiving support surface 3a and the plate surface of the second sub-transport plate 12 extending along the first direction D1. The sample (taking sample No. 2 62 as an example) is easily in a vertical state at the corner under the support of the inner side surface 71 of the first blocking mechanism 7a and the plate surface of the second sub-transport plate 12. At this time, since the length d1 is greater than the width of the sample 6 and greater than the height of the sample 6, for example, the height of the top surface of sample No. 2 62 in the first direction D1 exceeds the height of the first sensor 1a in the first direction D1, therefore, the first sensor 1a can sense that there is a sample at the first sensing position, so that the first spraying mechanism 2a sprays a force-applying substance toward sample No. 2 62 to apply force to sample No. 2 62 and knock the sample down on the first receiving support surface 3a to transform the sample into the horizontal state of sample No. 1 61.
[0060] For example, refer to Figure 4-5The sample collection device 10 further includes a second sensor (not shown) and a second ejection mechanism (not shown). The second sensor is disposed at a second sensing position on the second blocking mechanism 7b, and is configured to sense a sample located at the second end of the receiving bearing surface corresponding to the second blocking mechanism 7b and at a position substantially the same height as the second sensing position, wherein the height of the second sensing position is the height of the second sensing position relative to the receiving bearing surface corresponding to the second blocking mechanism 7b in the first direction D1, and the value of the height of the second sensing position is greater than the value of the width of the sample and greater than the value of the height of the sample and less than the value of the length of the sample; the second ejection mechanism is disposed on the second blocking mechanism 7b, and is configured to: when the second sensor senses that there is a sample at the second end of the corresponding receiving bearing surface and at a position substantially the same height as the second sensing position, eject a force-applying substance toward the sample to apply a force to the sample at a position substantially the same height as the second sensing position, and knock the sample down on the corresponding receiving bearing surface so that the sample is in a horizontal state. For example, the height of the second sensing position is equal to the height of the first sensing position. The working processes of the second sensor and the second ejection mechanism are respectively the same as those of the first sensor and the first ejection mechanism. For example, the positions of the second sensor and the second spraying mechanism are axisymmetric with respect to the positions of the first sensor and the first spraying mechanism, respectively, in the second direction D2.
[0061] For example, the force-applying material sprayed by the first spray mechanism and the second spray mechanism is compressed air, so that a good knocking-down effect can be achieved without causing contamination to the sample.
[0062] For example, refer to Figure 1 The sample collection device 10 further includes a control system 4, and the control system 4 is signal-connected (wireless signal connection or wired signal connection such as electrical connection) with the first sensor 1a and the second sensor, and the first spray mechanism 2a and the second spray mechanism. For example, the first sensor 1a and the second sensor perform real-time sensing, and transmit the sensing results to the control system 4 in real time. The control system 4 includes a judgment module, and the judgment module performs a judgment step to judge whether there is a sample at the first sensing position. If the judgment result is "yes", the control system 4 controls the first spray mechanism 2a to spray the force-applying substance. If the judgment result is "no", the control system 4 controls the first spray mechanism 2a not to spray the force-applying substance. Similarly, the judgment module also performs a judgment step to judge whether there is a sample at the second sensing position. If the judgment result is "yes", the control system 4 controls the second spray mechanism to spray the force-applying substance. If the judgment result is "no", the control system 4 controls the second spray mechanism not to spray the force-applying substance.
[0063] For example, refer to Figure 1The control system 4 can also be connected to the acquisition drive mechanism 5 by signal (wireless signal connection or wired signal connection such as electrical connection), and is configured to control the acquisition drive mechanism 5 to perform work and working parameters, such as motor speed, motor working time, etc.
[0064] For example, refer to Figure 3A The sample collection device 10 also includes a sample container configured to accommodate multiple samples. After manually sampling a target body (e.g., a human body), a large number of sampling tubes (samples 6) containing substances to be tested, such as nucleic acid sampling tubes or other types of detection sampling tubes, are placed in the sample container. The sample initial supply position P0 is located in the sample container, and the width of the sample container in the second direction D2 is greater than or equal to the length of each sub-transport plate in the second direction D2 and the length of each transport bearing surface in the second direction D2, and is greater than or equal to the length of each sub-receiving plate in the second direction D2 and the length of each receiving bearing surface in the second direction D2. When the first transport bearing surface 4a reaches the sample initial supply position P0, the first transport bearing surface 4a is inserted into the large number of samples 6, and a portion of the samples 6 at the sample initial supply position P0 will be carried on the first transport bearing surface 4a.
[0065] For example, the first blocking mechanism 7a is a first blocking plate, and the second blocking mechanism 7b is a second blocking plate. For example, the sample container has a first side wall and a second side wall opposite to each other in the second direction D2, for example, the first blocking plate and the first side wall form an integral structure, and the second blocking plate and the second side wall form an integral structure, so as to simplify the structure of the sample collection device 10.
[0066] Figure 6 Schematic diagram of a sample preparation device provided by an embodiment of the present disclosure. Figure 6 The sample preparation device 100 provided in an embodiment of the present disclosure includes any one of the sample collection devices 10 provided in an embodiment of the present disclosure and a sample transportation device 20 connected to the sample collection device 10. The sample transportation device 20 is configured to transport a plurality of samples arranged in a single row from the sample collection device 10. For example, the sample transportation device 20 transports the plurality of samples arranged in a single row to the next processing link for automatic counting, automatic collection of sample information one by one, etc., so as to realize the functions of efficient automatic sample collection and automatic transportation of the plurality of samples arranged in a single row formed by the sample collection device 10, laying a foundation for subsequent steps such as automatic counting and automatic collection of sample information one by one.
[0067] The above description is merely an exemplary embodiment of the present invention and is not intended to limit the protection scope of the present invention. The protection scope of the present invention is determined by the appended claims.
Claims
1. A sample collection device, characterized in that: The sample collection device comprises: A collection and transportation mechanism, configured to reciprocate along a first direction, comprising a transportation bearing surface intersecting the first direction and extending along a second direction as a whole, wherein the second direction is perpendicular to the first direction; a sample receiving mechanism having a receiving bearing surface intersecting the first direction, wherein the receiving bearing surface extends as a whole along the second direction and is offset from the transport bearing surface in a third direction, the third direction being perpendicular to both the first direction and the second direction; and The collecting driving mechanism is configured to drive the collecting transporting mechanism to reciprocate along the first direction to drive the transport bearing surface to reciprocate along the first direction, wherein: The transport carrying surface is configured to move along the first direction to a sampling position away from the receiving carrying surface to carry the sample, and is configured to move along the first direction to a first handover position close to the receiving carrying surface so that the sample carried on the transport carrying surface moves to the receiving carrying surface, the height of the first handover position in the first direction is not lower than the height of the receiving carrying surface in the first direction and is adjacent to the receiving carrying surface in the third direction, and the receiving carrying surface is a non-smooth surface with depressions and protrusions.
2. The sample collection device according to claim 1, characterized in that: The sample receiving mechanism comprises a plurality of receiving bearing surfaces, wherein the plurality of receiving bearing surfaces are respectively a first receiving bearing surface, a second receiving bearing surface, ..., an Nth receiving bearing surface, which are arranged in order from low to high in the first direction and staggered in the third direction, and the heights of the plurality of receiving bearing surfaces in the first direction are different from each other and the positions are fixed, and N is a positive integer greater than 1; The collection and transportation mechanism comprises a plurality of the transportation bearing surfaces, wherein the plurality of the transportation bearing surfaces are respectively a first transportation bearing surface, a second transportation bearing surface, ..., an Nth transportation bearing surface which are arranged in order from low to high in the first direction and staggered in the third direction; The first receiving bearing surface is located between the first transport bearing surface and the second transport bearing surface in the third direction; The first transport carrying surface and the second transport carrying surface are configured to move from low to high along the first direction at the same time to reach the first intersection positions corresponding to the first receiving carrying surface and the second receiving carrying surface at the same time, respectively, so that the sample carried on the first transport carrying surface is transferred to the first receiving carrying surface, and the sample carried on the second transport carrying surface is transferred to the second receiving carrying surface; The first transport carrying surface and the second transport carrying surface are configured to move from high to low simultaneously along the first direction to reach the sample initial supply position and the second handover position close to the first receiving carrying surface respectively at the same time, the height of the second handover position in the first direction is lower than the height of the first receiving carrying surface in the first direction and is adjacent to the first receiving carrying surface in the third direction, so that the sample at the sample initial supply position is carried on the first transport carrying surface and the sample carried on the first receiving carrying surface is carried on the second transport carrying surface, and when the second transport carrying surface moves from low to high along the first direction to the first handover position corresponding to the second receiving carrying surface, the sample carried on the second transport carrying surface is transferred to the second receiving carrying surface; The first intersection position and the second intersection position corresponding to the first receiving bearing surface are respectively located on a first side of the first receiving bearing surface away from the second receiving bearing surface and a second side of the first receiving bearing surface close to the second receiving bearing surface in the third direction.
3. The sample collection device according to claim 2, characterized in that: The collecting and transporting mechanism comprises a transport plate extending along the first direction, the transport plate comprises a plurality of sub-transport plates arranged in the first direction and staggered with each other in the third direction, the plurality of sub-transport plates comprise a first sub-transport plate and a second sub-transport plate, the first sub-transport plate has the first transport bearing surface, and the second sub-transport plate has the second transport bearing surface; The sample receiving mechanism comprises a receiving plate extending along the first direction, the receiving plate comprises a plurality of sub-receiving plates arranged in the first direction and staggered with each other in the third direction, the plurality of sub-receiving plates comprises a first sub-receiving plate and a second sub-receiving plate, the first sub-receiving plate has the first receiving bearing surface, and the second sub-receiving plate has the second receiving bearing surface; The collecting driving mechanism is configured to drive the first sub-transport plate and the second sub-transport plate to reciprocate along the first direction so that the first transport bearing surface and the second transport bearing surface can reciprocate along the first direction; The second sub-transportation plate is located between the first sub-receiving plate and the second sub-receiving plate in the third direction; When the first transport carrying surface is located at the first handover position and the sample carried on the first transport carrying surface is transferred to the first receiving carrying surface, the second sub-transport plate is configured to limit the sample located on the first receiving carrying surface so that the sample remains located on the first receiving carrying surface; and, When the second transport carrying surface is located at the second handover position and the sample carried on the first receiving carrying surface is transferred to the second transport carrying surface, the second sub-receiving plate is configured to limit the sample located on the second receiving carrying surface so that the sample remains located on the second receiving carrying surface.
4. The sample collection device according to claim 3, characterized in that: For the first receiving bearing surface, When the first transport bearing surface is located at the first handover position, the surfaces of the first sub-transport plate and the first sub-receiving plate facing each other in the third direction are in contact with each other, or there is a first interval between the first sub-transport plate and the first sub-receiving plate in the third direction, and the width of the first interval in the third direction is less than 1 / 2 of the width of the sample on the first receiving bearing surface in the third direction; When the second transport carrying surface is located at the second handover position, the surfaces of the second sub-transport plate and the first sub-receiving plate facing each other in the third direction are in contact with each other, or, there is a second interval between the second sub-transport plate and the first sub-receiving plate in the third direction, and the width of the second interval in the third direction is less than 1 / 2 of the width of the sample on the first receiving carrying surface in the third direction.
5. The sample collection device according to claim 2, characterized in that: A height difference between the first receiving bearing surface and the second receiving bearing surface in the first direction is substantially equal to a height difference between the first transport bearing surface and the second transport bearing surface in the first direction.
6. The sample collection device according to claim 2, characterized in that: The first transport bearing surface is a first inclined surface, the first inclined surface has a first side close to the receiving bearing surface in the third direction and a second side away from the receiving bearing surface, the height of the first side of the first inclined surface in the first direction is less than the height of the second side of the first inclined surface in the first direction, and the sample carried on the first inclined surface moves to the first receiving bearing surface along the direction from the second side of the first inclined surface to the first side of the first inclined surface; The second transport bearing surface is a second inclined surface and is substantially parallel to the first transport bearing surface.
7. The sample collection device according to claim 6, characterized in that: When the first transport bearing surface is located at the first handover position, The height of the first side of the first inclined surface in the first direction is substantially equal to the height of the first receiving and carrying surface in the first direction, or, A height of the first side of the first inclined surface in the first direction is higher than a height of the first receiving and carrying surface in the first direction.
8. The sample collection device according to claim 1, characterized in that: The depressions and protrusions on the receiving bearing surface form a regular pattern that is periodically arranged or an irregular pattern that is not periodically arranged.
9. The sample collection device according to claim 8, characterized in that: The regular pattern includes at least one of a wave shape and a zigzag shape.
10. The sample collection device according to any one of claims 2 to 9, characterized in that: The sample collection device is used to collect nucleic acid detection sampling tubes, and the sample is the nucleic acid detection sampling tube; The length of each nucleic acid detection sampling tube located on each receiving bearing surface in the second direction is greater than its height in the first direction and greater than its width in the third direction, the dimension of each receiving bearing surface in the third direction is greater than or equal to 1 times the width of the nucleic acid detection sampling tube in the third direction and less than 2 times the width of the nucleic acid detection sampling tube in the third direction, and a plurality of nucleic acid detection sampling tubes are arranged in a single row along the second direction on each receiving bearing surface; The Nth receiving carrying surface is configured as a carrying surface of a movable conveyor belt, and the movable conveyor belt is configured to move along the second direction to transport the plurality of nucleic acid detection sampling tubes arranged in a single row on the carrying surface of the movable conveyor belt along the second direction.
11. The sample collection device according to claim 3, characterized in that: The sample collection device also includes: A first blocking mechanism is located at a first end of each receiving and carrying surface in the second direction and is configured to prevent the sample located at the first end of each receiving and carrying surface from sliding off; and The second blocking mechanism is located at the second end of each receiving bearing surface in the second direction and is configured to block the sample located at the second end of each receiving bearing surface from sliding off.
12. The sample collection device according to claim 11, characterized in that: The sample has three dimensions of length, width and height in three mutually perpendicular directions, and the length is greater than the width and greater than the height; When the sample is located on the receiving bearing surface, the sample has a horizontal state and a vertical state; in the horizontal state, the length of the sample is along the second direction; In the vertical state, the length of the sample is along the first direction; The sample collection device also includes: a sensor disposed at a sensing position on at least one of the first blocking mechanism and the second blocking mechanism, configured to sense a sample located at a first end and / or a second end of the receiving support surface corresponding to at least one of the first blocking mechanism and the second blocking mechanism and at a position substantially the same as a height of the sensing position, wherein the height of the sensing position is a height of the sensing position relative to the receiving support surface corresponding to at least one of the first blocking mechanism and the second blocking mechanism in the first direction, and a value of the height of the sensing position is greater than a value of a width of the sample and greater than a value of a height of the sample and less than a value of a length of the sample; and The injection mechanism is arranged on at least one of the first blocking mechanism and the second blocking mechanism, and is configured to: when the sensor senses that the sample exists at the first end and / or the second end corresponding to the receiving support surface and at a position substantially the same height as the sensing position, inject a force-applying substance toward the sample to apply force to the sample at a position substantially the same height as the sensing position to knock the sample down onto the corresponding receiving support surface so that the sample is in the horizontal state.
13. The sample collection device according to claim 12, characterized in that: The force-applying substance is compressed air.
14. A sample preparation device, characterized in that: It comprises a sample collection device according to any one of claims 1 to 13 and a sample transport device connected to the sample collection device, wherein the sample transport device is configured to transport the sample from the sample collection device.