A nucleic acid extraction and amplification device

Abstract

The present application relates to a nucleic acid extraction amplification component fixing device, which includes a metal panel for placing the nucleic acid extraction amplification component; a spring pressure plate rotatably arranged on the upper side of the metal panel, used to press the fixed nucleic acid extraction amplification component on the upper surface of the metal panel, and a test groove is opened through the upper surface of the spring pressure plate; a transfer assembly, which is provided with multiple groups, and the multiple groups of transfer assemblies are spaced between the upper surface of the metal panel and the side wall of the spring pressure plate to realize the transfer of the spring pressure plate; a pressing assembly, which is arranged on the side of the metal panel away from the transfer assembly to press the spring pressure plate so that the spring pressure plate presses the nucleic acid extraction amplification component more stably and reliably. The present application has the effect of accurately fixing the required nucleic acid extraction amplification plastic component device without using special dedicated tools, and increasing the tightness, stability and reliability.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a nucleic acid extraction and amplification component fixing device. Background Art

[0002] The fixing technology for diagnostic reagent chips or cartridges in integrated nucleic acid extraction and amplification detection equipment is widely used in the research and development of medical devices, reagent chips and cartridges in the IVD diagnosis field. The reasonable design of this technology point is crucial to the ease of use, durability and stability of the detection equipment and supporting reagent consumables. At present, most of the fixing technologies on the market use a single buckle and spring pressing fixing method.

[0003] In the prior art, since a single buckle and spring press fixation is mostly used to fix a product, it is necessary to regularly replace inelastic springs or loose buckles during use. Therefore, when the experimenter does not have a good control over the use of operating force, it is easy to cause the fasteners and test parts to loosen, thus affecting the actual operation experience and experimental effects, and causing adverse effects on the test results. The current fixing technology cannot meet the needs of long-term stable use, which will cause experimental failures and reagent waste, and the detection equipment cannot be stably operated and used, making the experimental operation process unfriendly and unhumanized, and the reliability of the detection process is poor.

[0004] At present, the existing technology still has the following areas for improvement:

[0005] 1. Under the existing technology, this component of the detection equipment needs regular maintenance and replacement, and the design needs to be improved to improve the long-term stability and reliability of the equipment and achieve maintenance-free.

[0006] 2. During use, the reagent chip or cartridge may not be properly installed or in poor contact, which may lead to experimental failure. The design needs to be improved to improve the usability and stability of the product and avoid experimental failure. Utility Model Content

[0007] In order to accurately fix the required nucleic acid extraction and amplification plastic parts device without using special dedicated tools, thereby increasing the tightness, stability and reliability, the present application provides a nucleic acid extraction and amplification parts fixing device.

[0008] The present application provides a nucleic acid extraction and amplification component fixing device that adopts the following technical solution:

[0009] A nucleic acid extraction and amplification component fixing device, comprising:

[0010] A metal panel for placing nucleic acid extraction and amplification components;

[0011] A spring pressure plate is rotatably arranged on the upper side of the metal panel and is used to press the fixed nucleic acid extraction and amplification component onto the upper surface of the metal panel. A test groove is formed through the upper surface of the spring pressure plate.

[0012] The transfer assembly is provided with multiple groups, and the multiple groups of transfer assemblies are arranged at intervals between the metal panel and the side wall of the spring pressure plate to realize the transfer of the spring pressure plate;

[0013] A pressing component is arranged on the side of the metal panel away from the transfer component to press the spring pressure plate so that the spring pressure plate presses the nucleic acid extraction and amplification component more stably and reliably.

[0014] Preferably, the transfer assembly includes a positioning bracket and a threaded fixing pin, the positioning bracket is arranged on the upper surface of the metal panel and two are arranged at intervals, at least one transfer ear plate is arranged on the side wall of the spring pressure plate between the two positioning brackets, the threaded fixing pin passes through the transfer ear plate and the positioning bracket, and the threaded fixing pin is threadedly connected to the positioning bracket.

[0015] Furthermore, a torsion spring is sleeved on the outer wall of the threaded fixing pin, one end of the torsion spring is arranged on the rotating ear plate, and the other end of the torsion spring is arranged on the metal panel.

[0016] Preferably, the pressing assembly includes a C-shaped block, a pressing block, a rotating shaft and an elastic member. The C-shaped block is embedded in the metal panel. The pressing block is rotated between the two inner walls of the C-shaped block through the rotating shaft to press the spring pressure plate. There are multiple elastic members, and multiple elastic members are arranged between the pressing block and the inner bottom wall of the C-shaped block so that the pressing block always maintains a pressed state.

[0017] Furthermore, the pressing block includes a pressing head, a rotating block and a supporting plate, the pressing head is arranged on the top side wall of the rotating block, the spring pressing plate is pressed between the pressing head and the nucleic acid extraction and amplification component, the rotating shaft passes through the rotating block and the C-shaped block, the supporting plate is arranged on the side of the rotating block away from the pressing head, and the elastic member is arranged between the bottom wall of the support plate and the inner bottom wall of the C-shaped block.

[0018] Furthermore, the elastic member is a spring.

[0019] Compared with the prior art, the nucleic acid extraction and amplification component fixing device of the utility model has the following beneficial technical effects:

[0020] 1. When the utility model is used, the nucleic acid extraction and amplification component is pressed by the spring pressure plate to fit tightly with the metal panel, thereby improving the consistency and reliability of the experiment to a greater extent.

[0021] 2. When the utility model is used, the maximum error of the repetitive positioning of the spring pressure plate is between 0.02-0.05 mm through the transfer assembly, which improves the consistency of the repetitive positioning of the nucleic acid extraction and amplification component. The setting of the torsion spring on the outer wall of the threaded fixing pin makes the overall stability of the fixing device significantly better than when the spring pressure plate is set alone.

[0022] 3. When the utility model is used, the stability of the spring pressure plate during pressing is further improved through the pressing assembly. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 This is an axial schematic diagram of the overall structure of a nucleic acid extraction and amplification component fixing device mainly embodied in the utility model;

[0024] Figure 2 This is a schematic diagram of a state in which a spring pressure plate of a nucleic acid extraction and amplification component fixing device is rotated 60°;

[0025] Figure 3 It is an axial side schematic diagram mainly showing the overall structure of the pressing assembly of the utility model.

[0026] Figure numerals: 1. Metal panel; 2. Spring pressure plate; 3. Transfer assembly; 31. Positioning bracket; 32. Threaded fixing pin; 4. Pressing assembly; 41. U-shaped block; 42. Pressing block; 421. Pressing head; 422. Transfer block; 423. Support plate; 43. Rotating shaft; 44. Elastic member; 5. Test slot; 6. Transfer ear plate; 7. Torsion spring. DETAILED DESCRIPTION

[0027] In order to make the purpose, technical scheme and advantages of the embodiment of the present application clearer, the technical scheme of the embodiment of the present application will be clearly and completely described in conjunction with the drawings of the embodiment of the present application. Obviously, the described embodiment is a part of the embodiment of the present application, not all of the embodiments. Based on the described embodiment of the present application, all other embodiments obtained by ordinary technicians in this field without creative work belong to the scope of protection of this application.

[0028] Unless otherwise defined, the technical terms or scientific terms used herein shall have the common meanings understood by persons with ordinary skills in the field to which this application belongs. The words "one" or "an" and the like used in the patent application specification and claims of this application do not indicate a quantity limitation, but indicate the existence of at least one.

[0029] The following is combined with Figure 1-3 This application is described in further detail.

[0030] The embodiment of the present application discloses a nucleic acid extraction and amplification component fixing device.

[0031] Reference Figure 1-Figure 3 A nucleic acid extraction and amplification component fixing device comprises a metal panel 1, a spring pressure plate 2, a transfer assembly 3 and a pressing assembly 4. The nucleic acid extraction and amplification component is placed on the metal panel 1. The spring pressure plate 2 is rotatably installed on the metal upper surface through the transfer assembly 3 to press and fix the nucleic acid extraction and amplification component on the metal panel 1. A test groove 5 is penetrated on the upper surface of the spring pressure plate 2 for facilitating nucleic acid testing after the nucleic acid extraction and amplification component is fixed. The pressing assembly 4 is installed on the side of the metal panel 1 away from the transfer assembly 3 to press the spring pressure plate 2, so that the spring pressure plate 2 presses the nucleic acid extraction and amplification component more stably and reliably.

[0032] Reference Figure 1 and Figure 2 Furthermore, multiple groups of transfer components 3 are installed, and the multiple groups of transfer components 3 are evenly installed between the upper surface of the metal panel 1 and the side wall of the spring pressure plate 2 to achieve stable transfer of the spring pressure plate 2. In this embodiment, the transfer components 3 are preferably three groups.

[0033] The transfer assembly 3 includes a positioning bracket 31 and a threaded fixing pin 32. The positioning bracket 31 is welded and fixed on the upper surface of the metal panel 1 and two are arranged at intervals. At least one transfer ear plate 6 is integrally formed on the side wall of the spring pressure plate 2 between the two positioning brackets 31. In this embodiment, there are preferably two transfer ear plates 6, and the two transfer ear plates 6 are spaced apart on the inner sides of the two positioning brackets 31. The threaded fixing pin 32 passes through the transfer ear plate 6 and the positioning bracket 31, and the threaded fixing pin 32 is threadedly connected to the positioning bracket 31, thereby realizing the disassembly and installation of the spring pressure plate 2 and ensuring the stability of the transfer pressing.

[0034] The threaded fixing pin 32 is located on the outer wall between the two rotating ear plates 6 and is sleeved with a torsion spring 7. One end of the torsion spring 7 is fixed on the rotating ear plate 6, and the other end of the torsion spring 7 is fixed on the metal panel 1. The arrangement of the torsion spring 7 on the outer wall of the threaded fixing pin 32 makes the overall stability of the fixing device 60% better than when the spring pressure plate 2 is arranged alone.

[0035] Reference Figure 1-Figure 3 In a further embodiment, the pressing assembly 4 includes a C-shaped block 41, a pressing block 42, a rotating shaft 43 and an elastic member 44. The C-shaped block 41 is embedded in the metal panel 1 and its upper surface is flush with the upper surface of the metal panel 1. The pressing block 42 is rotated and installed between the two inner walls of the C-shaped block 41 through the rotating shaft 43 to press the spring pressure plate 2. A plurality of elastic members 44 are provided, and a plurality of elastic members 44 are installed between the pressing block 42 and the inner bottom wall of the C-shaped block 41 so that the pressing block 42 always maintains a pressing state. In this embodiment, the elastic member 44 is preferably a spring.

[0036] Further, the pressing block 42 includes a pressing head 421, a rotating block 422 and a support plate 423. The pressing head 421 is integrally formed on the side wall of the top of the rotating block 422 facing the spring pressing plate 2. The spring pressing plate 2 is pressed between the pressing head 421 and the nucleic acid extraction and amplification component. The rotating shaft 43 passes through the rotating block 422 and the U-shaped block 41. The support plate 423 is integrally formed on the side of the rotating block 422背离 the pressing head 421 and is perpendicular to the rotating block 422. The elastic member 44 is welded and fixed between the bottom wall of the support plate 423 and the inner bottom wall of the U-shaped block 41, so that the pressing block 42 always maintains a pressing state through the elastic potential energy of the spring.

[0037] The above are all the preferred embodiments of this application, and the protection scope of this application is not limited accordingly. Therefore, all equivalent changes made according to the structure, shape, and principle of this application shall be covered within the protection scope of this application. It should be noted that there is an unclear expression "转设块422背离压头421的一侧且垂直于转设块422设置" in the original text. I translated it as "the side of the rotating block 422背离 the pressing head 421 and is perpendicular to the rotating block 422" with "背离" left untranslated as it seems to be an incorrect or unclear term in this context. You may need to check and correct it if necessary.

Claims

1. A nucleic acid extraction and amplification device fixing device, characterized in that: include: A metal panel (1) for placing a nucleic acid extraction and amplification component; A spring pressure plate (2) is rotatably arranged on the upper side of the metal panel (1) and is used to press the fixed nucleic acid extraction and amplification component onto the upper surface of the metal panel (1); a test groove (5) is provided through the upper surface of the spring pressure plate (2); The transfer assembly (3) is provided with a plurality of groups, and the plurality of groups of the transfer assembly (3) are arranged at intervals between the upper surface of the metal panel (1) and the side wall of the spring pressure plate (2) to realize the transfer of the spring pressure plate (2); A pressing component (4) is arranged on a side of the metal panel (1) away from the transfer component (3) to press the spring pressure plate (2) so that the pressing of the spring pressure plate (2) on the nucleic acid extraction and amplification component is more stable and reliable.

2. A nucleic acid extraction and amplification component fixing device according to claim 1, characterized in that: The transfer assembly (3) comprises a positioning bracket (31) and a threaded fixing pin (32); the positioning bracket (31) is arranged on the upper surface of the metal panel (1) and two positioning brackets (31) are arranged at intervals; at least one transfer ear plate (6) is arranged on the side wall of the spring pressure plate (2) between the two positioning brackets (31); the threaded fixing pin (32) penetrates the transfer ear plate (6) and the positioning bracket (31), and the threaded fixing pin (32) is threadedly connected to the positioning bracket (31).

3. A nucleic acid extraction and amplification component fixing device according to claim 2, characterized in that: A torsion spring (7) is sleeved on the outer wall of the threaded fixing pin (32), one end of the torsion spring (7) is arranged on the rotating ear plate (6), and the other end of the torsion spring (7) is arranged on the metal panel (1).

4. A nucleic acid extraction and amplification component fixing device according to claim 1, characterized in that: The pressing assembly (4) comprises a C-shaped block (41), a pressing block (42), a rotating shaft (43) and an elastic member (44); the C-shaped block (41) is embedded in the metal panel (1); the pressing block (42) is rotated between two inner walls of the C-shaped block (41) via the rotating shaft (43) to press the spring pressure plate (2); a plurality of elastic members (44) are provided, and the plurality of elastic members (44) are provided between the pressing block (42) and the inner bottom wall of the C-shaped block (41) so that the pressing block (42) always maintains a pressing state.

5. A nucleic acid extraction and amplification component fixing device according to claim 4, characterized in that: The pressing block (42) comprises a pressing head (421), a rotating block (422) and a supporting plate (423); the pressing head (421) is arranged on the top side wall of the rotating block (422); the spring pressing plate (2) is pressed between the pressing head (421) and the nucleic acid extraction and amplification component; the rotating shaft (43) passes through the rotating block (422) and the U-shaped block (41); the supporting plate (423) is arranged on a side of the rotating block (422) away from the pressing head (421); and the elastic member (44) is arranged between the bottom wall of the supporting plate (423) and the inner bottom wall of the U-shaped block (41).

6. A nucleic acid extraction and amplification component fixing device according to claim 5, characterized in that: The elastic member (44) is a spring.

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