Nanometer wafer for nanometer infiltration promotion

By designing structures such as hollow substrates, guided sliding cavity in nanochips, and using mobile microneedles to drive the quantitative release of essence, the problem of uneven nutrient penetration in the prior art is solved, and efficient and uniform nutrient penetration effect is achieved.

CN222738363UActive Publication Date: 2025-04-11SHENYANG PHARMA UNIV
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Patent Information

Application Number
CN202420598631.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-03-26
Publication Date
2025-04-11
Estimated Expiration
2034-03-26

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Abstract

A plurality of groups of guide sliding cavities are arrayed at the bottom of a hollow substrate, movable microneedles are inserted into the inner walls of the guide sliding cavities in a sliding manner, the movable microneedles penetrate through the bottom of the hollow substrate, and the top ends of the movable microneedles are connected with limiting pressing blocks. A baffle connected with the inner wall of the hollow substrate is arranged at the top of the limiting pressing block, a permeation groove is formed in the side wall of the movable microneedle, a sealing plate connected with the permeation groove in an inserted mode is connected to the inner wall of the guiding sliding cavity, and a conveying sliding groove communicated with the interior of the guiding sliding cavity is formed in the top of the guiding sliding cavity; quantitative liquid storage space is formed among the conveying sliding groove, the upper portion of the permeation groove and the sealing plate, essence released quantitatively can be evenly permeated into the skin, and the efficient permeation effect of nutrients of the essence is achieved; the movable microneedle can slide in the guide sliding cavity, so that the movable microneedle can be slowly inserted into the cuticle of the skin, pain cannot be brought to a user, and use is safe.
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Description

Technical Field

[0001] The utility model relates to the technical field of percutaneous delivery devices, and in particular to a nano-wafer used for nano-permeation promotion. Background Art

[0002] Nanochip is a special tool for promoting nano-permeation developed according to the structure of human skin. It is carved from single crystal silicon by nanotechnology. The surface of the nanochip is a series of microneedle arrays, which can open the outermost stratum corneum of the skin without damaging the dermis, greatly improving the penetration of nutrients. The biocompatibility of single crystal silicon also ensures the safety of nanocrystals during use. Existing nanochips such as Figure 1 As shown, it includes a substrate and a microneedle array arranged on one side of the substrate. Although the existing nano-chip can complete the nutrient penetration work, the nutrient penetration is uneven and the effect of quantitative nutrient release cannot be achieved, thereby failing to achieve the effect of efficient nutrient penetration. Utility Model Content

[0003] According to the technical problem raised above, a nanochip for nano-infiltration is provided.

[0004] The technical means adopted by the utility model are as follows:

[0005] A nanochip for nano-infiltration promotion comprises a hollow substrate, wherein the bottom array of the hollow substrate comprises a plurality of guide slide cavities, the inner wall of the guide slide cavity is slidably plugged with a movable microneedle, the movable microneedle is penetrated through the bottom of the hollow substrate, the top of the movable microneedle is connected to a limiting pressing block, the top of the limiting pressing block is provided with a baffle connected to the inner wall of the hollow substrate, the side wall of the movable microneedle is provided with an infiltration groove, the inner wall of the guide slide cavity is connected with a sealing plate plugged with the infiltration groove, the top of the guide slide cavity is provided with a conveying chute communicated with the inside of the guide slide cavity, and a quantitative liquid storage space is formed between the conveying chute, the upper part of the infiltration groove and the sealing plate.

[0006] Furthermore, a liquid filling plug is inserted into the side of the hollow substrate.

[0007] Furthermore, a mounting groove is provided on the side of the hollow substrate.

[0008] Furthermore, the hollow substrate, the guide slide cavity and the sealing plate are manufactured in one piece.

[0009] Furthermore, the bottom surface of the guide slide cavity and the bottom surface of the hollow substrate are in the same plane.

[0010] Furthermore, the cross-sectional area of ​​the movable microneedle is smaller than the cross-sectional area of ​​the limiting pressing block.

[0011] Furthermore, the diameter of the penetration groove is gradually increased from bottom to top.

[0012] Compared with the prior art, the utility model has the following advantages:

[0013] The utility model is provided with a hollow substrate, a guide sliding cavity, a conveying chute, a sealing plate, a movable microneedle, a penetration groove, a limit pressing block and a baffle. When the nanochip is in use, the movable microneedle drives the penetration groove to move upward, and a quantitative liquid storage space can be formed between the conveying chute, the upper part of the penetration groove and the sealing plate. After the quantitative liquid storage space is filled with the essence liquid in the hollow substrate, when the movable microneedle moves downward, it flows to the lower space of the penetration groove and when the movable microneedle is inserted into the skin next time, the quantitatively released essence liquid is evenly penetrated into the skin, so that the nutrients of the essence liquid achieve an efficient penetration effect; at the same time, the movable microneedle can slide in the guide sliding cavity, so that the movable microneedle can be slowly inserted into the stratum corneum of the skin, which will not cause pain to the user and is safer to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0015] Figure 1 A schematic diagram of the structure of a nano-chip for nano-infiltration promotion provided by the utility model;

[0016] Figure 2 A schematic diagram of the structure of a nano-chip for nano-infiltration provided by the utility model Figure 1 ;

[0017] Figure 3 A schematic diagram of the structure of a nano-chip for nano-infiltration provided by the utility model Figure 2 ;

[0018] Figure 4 A schematic diagram of the structure of a nano-chip for nano-infiltration provided by the utility model Figure 3 ;

[0019] Figure 5 A cross-sectional view of a nano-wafer for nano-infiltration promotion provided by the utility model Figure 1 ;

[0020] Figure 6 The utility model provides Figure 5 The enlarged view of point A in the middle;

[0021] Figure 7 A cross-sectional view of a nano-wafer for nano-infiltration promotion provided by the utility model Figure 2 ;

[0022] Figure 8 for Figure 7 The enlarged view of point B in the middle;

[0023] Fig. 9 A schematic diagram of the structure of the mobile microneedle provided by the utility model;

[0024] In the figure: 1. hollow substrate; 2. liquid adding plug; 3. mounting groove; 4. guide slide cavity; 5. conveying slide groove; 6. sealing plate; 7. moving microneedle; 8. penetration groove; 9. limit pressing block; 10. baffle 10. DETAILED DESCRIPTION

[0025] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments of the present invention can be combined with each other. The present invention will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0026] In order to make the purpose, technical solution and advantages of the embodiments of the utility model clearer, the technical solution in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. The following description of at least one exemplary embodiment is actually only illustrative and is by no means intended to limit the utility model and its application or use. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0027] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the utility model. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, it indicates the presence of features, steps, operations, devices, components and / or combinations thereof.

[0028] Unless otherwise specifically stated, the relative arrangement, numerical expressions and numerical values ​​of the parts and steps described in these embodiments do not limit the scope of the utility model. At the same time, it should be clear that, for ease of description, the sizes of the various parts shown in the accompanying drawings are not drawn according to the actual proportional relationship. The technology, method and equipment known to those of ordinary skill in the relevant field may not be discussed in detail, but in appropriate cases, the technology, method and equipment should be considered as a part of the specification. In all examples shown and discussed here, any specific value should be interpreted as being merely exemplary, rather than as a limitation. Therefore, other examples of exemplary embodiments may have different values. It should be noted that similar reference numerals and letters represent similar items in the following drawings, so once a certain item is defined in an accompanying drawing, it does not need to be further discussed in subsequent drawings.

[0029] In the description of the present utility model, it needs to be understood that the directions or positional relationships indicated by directional words such as "front, back, up, down, left, right", "lateral, vertical, perpendicular, horizontal" and "top, bottom" are usually based on the directions or positional relationships shown in the drawings. They are only for the convenience of describing the present utility model and simplifying the description. Unless otherwise stated, these directional words do not indicate or imply that the device or element referred to must have a specific direction or be constructed and operated in a specific direction. Therefore, they cannot be understood as limiting the scope of protection of the present utility model: the directional words "inside and outside" refer to the inside and outside relative to the contours of each component itself.

[0030] For ease of description, spatially relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used here to describe the spatial positional relationship between a device or feature and other devices or features as shown in the figure. It should be understood that spatially relative terms are intended to include different orientations of the device in use or operation in addition to the orientation described in the figure. For example, if the device in the accompanying drawings is inverted, the device described as "above other devices or structures" or "above other devices or structures" will be positioned as "below other devices or structures" or "below other devices or structures". Thus, the exemplary term "above" can include both "above" and "below". The device can also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatially relative descriptions used here are interpreted accordingly.

[0031] In addition, it should be noted that the use of terms such as "first" and "second" to limit components is only for the convenience of distinguishing the corresponding components. If not otherwise stated, the above terms have no special meaning and therefore cannot be understood as limiting the scope of protection of the utility model.

[0032] Example 1

[0033] like Figures 1 to 9 As shown, the utility model provides a nano-chip for nano-infiltration promotion, including a hollow substrate 1, wherein the bottom array of the hollow substrate 1 has multiple groups of guide sliding cavities 4, and the inner wall of the guide sliding cavity 4 is slidably plugged with a mobile microneedle 7, and the mobile microneedle 7 is penetrated through the bottom of the hollow substrate 1, and the top of the mobile microneedle 7 is connected to a limited pressing block 9, and the top of the limited pressing block 9 is provided with a baffle 10 connected to the inner wall of the hollow substrate 1, and the side wall of the mobile microneedle 7 is provided with a penetration groove 8, and the inner wall of the guide sliding cavity 4 is connected with a sealing plate 6 plugged with the penetration groove 8, and the top of the guide sliding cavity 4 is provided with a conveying chute 5 communicated with the inside of the guide sliding cavity 4, and a quantitative liquid storage space is formed between the conveying chute 5, the upper part of the penetration groove 8 and the sealing plate 6.

[0034] A liquid adding plug 2 is inserted into the side of the hollow substrate 1 . This arrangement facilitates the replenishment of essence liquid to the hollow substrate 1 and can effectively improve the working efficiency of the hollow substrate 1 .

[0035] The side of the hollow substrate 1 is provided with a mounting groove 3 , which makes it easy for the hollow substrate 1 to be connected to external devices and can effectively improve the installation efficiency of the hollow substrate 1 .

[0036] The hollow substrate 1, the guide sliding cavity 4 and the sealing plate 6 are made in one piece. Such a configuration can effectively improve the tightness among the hollow substrate 1, the guide sliding cavity 4 and the sealing plate 6 and can effectively prevent the occurrence of breakage.

[0037] The bottom surface of the guide slide cavity and the bottom surface of the hollow substrate are in the same plane. This arrangement can facilitate the insertion of the mobile microneedle 7 into the skin and can effectively improve the working efficiency and working effect of the mobile microneedle 7.

[0038] The cross-sectional area of ​​the movable microneedle is smaller than that of the limiting pressing block. This arrangement can facilitate the limiting pressing block 9 to seal the opening at the top of the conveying chute 5, effectively improving the working effect of the limiting pressing block 9.

[0039] The working principle of the utility model is as follows: firstly, the hollow substrate 1 is installed on the use device, and then when the nano wafer is used, the essence is first added into the hollow substrate 1, and then the mobile microneedle 7 is inserted into the skin. During the insertion process of the mobile microneedle 7, the mobile microneedle 7 can slide in the guide sliding cavity 4, so that the mobile microneedle 7 is slowly inserted into the stratum corneum of the skin, and the user will not feel pain;

[0040] like Figure 8As shown, the essence in the hollow substrate 1 flows into the quantitative liquid storage space through the top opening of the delivery chute 5. When the moving microneedle 7 contacts the skin, the moving microneedle is forced to slide upward, and the essence in the quantitative liquid storage space flows into the lower space of the penetration groove 8 through the gap between the sealing plate 6 and the penetration groove 8 and flows along the plug-in end of the moving microneedle 7 to the plug-in point of the skin; when the limiting pressing block 9 is separated from the guide sliding cavity 4, the penetration groove 8 moves upward, and the limiting pressing block 9 touches the baffle 10, the essence in the lower space of the penetration groove 8 is inserted into the skin by the moving microneedle 7, and the liquid infiltration is completed.

[0041] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, ordinary technicians in this field should understand that they can still modify the technical solutions recorded in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not make the essence of the corresponding technical solution deviate from the scope of the technical solution of the embodiments of the utility model.

Claims

1. A nanocrystalline chip for nano-infiltration promotion, characterized in that: It comprises a hollow substrate, wherein the bottom array of the hollow substrate comprises a plurality of guide sliding cavities, the inner wall of the guide sliding cavity is slidably plugged with a movable microneedle, the movable microneedle is penetrated through the bottom of the hollow substrate, the top of the movable microneedle is connected with a limiting pressing block, the top of the limiting pressing block is provided with a baffle connected with the inner wall of the hollow substrate, the side wall of the movable microneedle is provided with a penetration groove, the inner wall of the guide sliding cavity is connected with a sealing plate plugged with the penetration groove, the top of the guide sliding cavity is provided with a conveying chute communicating with the inside of the guide sliding cavity, and a quantitative liquid storage space is formed between the conveying chute, the upper part of the penetration groove and the sealing plate.

2. A nanocrystalline wafer for nano-infiltration promotion according to claim 1, characterized in that: A liquid adding plug is inserted into the side of the hollow substrate.

3. A nanocrystalline wafer for nano-infiltration promotion according to claim 1 or 2, characterized in that: The side of the hollow substrate is provided with a mounting groove.

4. A nanocrystalline wafer for nano-infiltration promotion according to claim 1 or 2, characterized in that: The hollow substrate, the guide sliding cavity and the sealing plate are made in one piece.

5. A nanocrystalline wafer for nano-infiltration promotion according to claim 1 or 2, characterized in that: The bottom surface of the guide slide cavity and the bottom surface of the hollow substrate are in the same plane.

6. A nanocrystalline wafer for nano-infiltration promotion according to claim 1, characterized in that: The cross-sectional area of ​​the movable microneedle is smaller than the cross-sectional area of ​​the limiting pressing block.

7. A nanocrystalline wafer for nano-infiltration promotion according to claim 1, characterized in that: The diameter of the penetration groove is gradually enlarged from bottom to top.