Mixed flow type double-runner plate layer for freeze dryer

By adopting a mixed flow dual-channel design and mixed flow zone in the freeze-dryer plate layer, the problems of low flowability and poor temperature field uniformity of silicone oil in large-size plate layers are solved, and more efficient silicone oil flow and temperature uniformity are achieved.

CN222824783UActive Publication Date: 2025-05-02TIANJIN CANAN PHARM EQUIP CO LTD
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Patent Information

Application Number
CN202421802047.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-29
Publication Date
2025-05-02
Estimated Expiration
2034-07-29

AI Technical Summary

Technical Problem

When the lyophilized dryer plate size is large, the silicone oil has low fluidity, poor heat exchange effect and reduced temperature field distribution uniformity, which cannot meet the process requirements of drug production.

Method used

The mixed flow double-flow channel plate design is adopted. By setting up spacers and two sets of inlet and outlet ports, the single flow channel is turned into a double flow channel, increasing the flow area and reducing the flow channel resistance, and at the same time, a mixed flow zone is set in the flow channel to enhance temperature uniformity.

Benefits of technology

Under the same pump pressure, the circulating flow rate of the silicone oil in the plate layer doubles, the flow rate is improved, and the heat exchange effect is enhanced, which significantly improves the temperature field uniformity of the large-size plate layer.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a freeze dryer mixed flow type double flow channel plate layer, which comprises a frame and panels respectively welded on two sides of the frame, a plurality of division bars used for forming flow channels and arranged in a staggered manner are arranged between the panels, two groups of flow inlets and flow outlets are symmetrically arranged on the side wall of the frame, and the flow inlets and the flow outlets are communicated with the inside of the frame; the interior of the frame is divided into a plurality of main flow channels by a plurality of division bars, a spacing bar is arranged in the middle of each main flow channel, and each spacing bar divides the main flow channel where the spacing bar is located into two branch flow channels; by arranging the spacing bars and the two groups of flow inlets and flow outlets, a single flow channel is changed into double flow channels, the flow area is increased, the flow channel resistance is reduced, the plate layer silicone oil circulation flow is multiplied under the same pump pressure, the flow speed is increased, and the heat exchange effect is enhanced; by arranging the flow mixing area, two strands of silicone oil can be intersected and mixed in the flow mixing area, so that the temperature uniformity is enhanced, and the temperature field uniformity of a large-specification board layer is remarkably improved.
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Description

Technical Field

[0001] The utility model relates to the field of freeze dryer plate layers, in particular to a mixed flow type double flow channel plate layer for a freeze dryer. Background Art

[0002] The plate layer is one of the key components in the freeze dryer. Its main function is to place the materials that need to be freeze-dried and to transfer heat to ensure that the materials complete the freeze-drying process smoothly. During the operation of the freeze dryer, the heat-carrying medium enters the inner cavity of the plate layer to achieve the cooling and heating effects. Usually, a partition is also arranged in the inner cavity to adjust the flow direction of the heat-carrying medium, so that the heat inside and outside the plate layer can be fully exchanged. In addition, the partition is also the supporting structure of the plate layer, and a certain layout density must be guaranteed;

[0003] Industrial pharmaceutical freeze dryers usually use silicone oil as a heat carrier. The silicone oil flows in the flow channel inside the drying chamber plate layer, releasing the cold or heat it carries to the material. In order to maximize the use of space, strengthen the heat exchange between the upper and lower surfaces of the plate layer, and ensure the stability of the temperature field, the plate layer flow channel is generally a single flow channel flat shape, and the silicone oil flows in a serpentine shape;

[0004] The inventors combined relevant technologies and found in actual applications that when the plate layer specifications are larger, the fluidity and heat exchange effect of the silicone oil drop sharply, causing the uniformity of the temperature field distribution of the plate layer to deteriorate sharply, and cannot meet the process requirements of drug production. Therefore, there is an urgent need for a plate layer suitable for an industrial pharmaceutical freeze dryer. Utility Model Content

[0005] In order to solve the problems in the prior art that when the plate layer specifications are large, the fluidity of silicone oil is low, the heat exchange effect is poor, and the uniformity of temperature field distribution is reduced, the utility model provides a mixed flow type double flow channel plate layer for a freeze dryer;

[0006] The utility model provides a mixed flow type double flow channel plate layer for a freeze dryer adopts the following technical solution:

[0007] A mixed-flow double-channel plate layer for a freeze dryer, comprising a frame and panels welded to both sides of the frame, a plurality of staggered spacers for forming channels are arranged between the panels, two groups of inlets and outlets are symmetrically arranged on the side wall of the frame, and the inlets and outlets are both connected to the inside of the frame; the inside of the frame is divided by a plurality of spacers to form a plurality of main channels, a spacer is arranged in the middle of each of the main channels, and each of the spacers divides the main channel where it is located into two branch channels;

[0008] Furthermore, the adjacent main channels are connected end to end, and the end of the branch channel in the same main channel and the end of the branch channel in the adjacent main channel form a mixed flow area;

[0009] Furthermore, the top end of the spacer bar is provided with a guide angle toward the incoming flow direction;

[0010] Furthermore, the guide angle is 45 degrees;

[0011] Furthermore, the distance between the spacer and the frame is set to a, the width of the diversion channel is set to c, and 0.5c≤a≤0.9c;

[0012] Furthermore, the distance between the partition bar and the frame is set to b, where b=2a.

[0013] In summary, the beneficial effects of the utility model are:

[0014] The utility model converts a single flow channel into a double flow channel by arranging a spacer bar and two groups of inlets and outlets, thereby increasing the flow area and reducing the flow channel resistance, so that the circulation flow rate of the plate layer silicone oil is doubled, the flow rate is increased, and the heat exchange effect is enhanced under the same pump pressure; by arranging a mixed flow zone, two streams of silicone oil can intersect and mix in the mixed flow zone, thereby enhancing temperature uniformity and significantly improving the temperature field uniformity of large-sized plate layers. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a front view cross-sectional schematic diagram of the specific structure of the utility model;

[0016] Figure 2 This is a schematic cross-sectional view of the main flow channel after the spacer strips are hidden in the utility model;

[0017] Figure 3 It is an enlarged schematic diagram of the mixed flow area structure of the utility model;

[0018] Figure 4 It is a schematic top view of a partial structure of the utility model.

[0019] As shown in the figure: 1-frame, 2-spacer, 3-spacer, 31-guide angle, 4-panel, 5-mixing area, 6-inlet, 7-outlet, 8-main channel, 9-dividing channel. DETAILED DESCRIPTION

[0020] The following is combined with Figure 1 -Attached Figure 4 The utility model is further described in detail:

[0021] The utility model embodiment discloses a mixed flow type double flow channel plate layer for a freeze dryer, such as Figure 1 , Figure 2 , Figure 4As shown, a mixed-flow double-channel plate layer for a freeze dryer of the utility model comprises a frame 1 and panels 4 respectively welded to both sides of the frame 1, a plurality of staggered spacers 2 for forming flow channels are arranged between the panels 4, and two groups of inlets 6 and outlets 7 are symmetrically arranged on the side wall of the frame 1, and the inlets 6 and outlets 7 are both connected to the inside of the frame 1; the inside of the frame 1 is divided by a plurality of spacers 2 to form a plurality of main channels 8, and a spacer 3 is arranged in the middle of each main channel 8, and each spacer 3 divides the main channel 8 in which it is located into two branch channels 9; in the present embodiment, one end of each spacer 2 is connected to the frame 1 to form the main channel 8, and in order to facilitate the distribution of the main channel 8, Figure 2 The schematic diagram of the main flow channel 8 behind the spacer bar 3 is hidden, wherein adjacent main flow channels 8 are connected end to end, and the silicone oil flows in the main flow channel 8 in a serpentine manner. Figure 1 As shown, both ends of the spacer bar 3 are not connected to the frame 1. By providing the spacer bar 3 and two groups of inlets 6 and outlets 7, the main channel 8 of the single-channel form is changed into a double-channel form. This arrangement effectively reduces the number of turns and the flow length of the channel. At the same time, the flow area is larger, so that the flow resistance of the silicone oil is smaller, the flow rate is faster and the heat exchange is better under the same pump pressure. Combined with the double streams of silicone oil flowing in from the two groups of inlets 6, silicone oil flows into the two branch channels 9 at the same time, thereby forming a double-channel mode. Therefore, the silicone oil flow rate can be greatly improved, thereby making the temperature field uniformity of the plate layer better. It is worth noting that in the present application, two groups of inlets 6, outlets 7 and two branch channels 9 are taken as an example. The number of inlets 6 and outlets 7 can be further increased by simply adding a corresponding number of branch channels 9. However, the entire plate layer needs to be connected to the inlets 6 and outlets 7 through hoses and clamps. Adding too many inlets 6 and outlets 7 will greatly restrict the movement of the entire plate layer in the later stage. Therefore, based on comprehensive considerations, two groups of inlets 6 and outlets 7 should be the optimal way.

[0022] like Figure 1 , Figure 2 , Figure 3 As shown, adjacent main channels 8 are connected end to end, and the ends of the branch channels 9 in the same main channel 8 and the ends of the branch channels 9 in the adjacent main channel 8 form a mixed flow area 5; in this embodiment, by setting the mixed flow area 5, the silicone oil in the two branch channels 9 can intersect in the mixed flow area 5, which increases the local flow velocity of the silicone oil, strengthens the temperature mixing effect of the two silicone oils, and further improves the uniformity of the temperature field of the large-scale plate layer. It is worth noting that the mixing effect of the mixed flow area 5 will be affected by the width of the branch channel 9, the length of the spacer 3, and the length of the spacer 2. Therefore, the parameter range is given for the above related column structure, such as Figure 3As shown, the distance between the spacer bar 3 and the frame 1 is set to a, the width of the diversion channel 9 is set to c, 0.5c≤a≤0.9c; the distance between the spacer bar 2 and the frame 1 is set to b, b=2a; under the relevant parameters, the mixing effect of the mixing area 5 is the best.

[0023] like Figure 1 , Figure 3 As shown, a guide angle 31 is provided at the top of the spacer bar 3 toward the incoming flow direction; in this embodiment, by setting the guide angle 31, the flow guiding effect of the spacer bar 3 is improved, and the mixing effect of the two silicone oils in the mixed flow area 5 is strengthened. Preferably, the guide angle 31 is 45 degrees.

[0024] The implementation principle of the embodiment of the utility model is:

[0025] Silicone oil is introduced into the two inlets 6 at the same time, and the silicone oil enters the main channel 8. When passing through the spacer bar 3, the silicone oil is divided into two paths and enters the two branch channels 9 at the same time, and enters the mixed flow area 5 at the end of the branch channel 9. The two paths of silicone oil are turned and changed in the mixed flow area 5, and then partially redistributed and enter different branch flow areas of the next main channel 8. The above process is repeated until it flows out from the two outlets 7.

[0026] The above shows and describes the basic principle and main features of the utility model and the advantages of the utility model. The various components mentioned in the utility model are common technologies in the existing field. The technicians in this industry should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only to illustrate the principles of the utility model. Without departing from the spirit and scope of the utility model, the utility model will have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents.

Claims

1. A mixed flow double-channel plate layer for a freeze dryer, comprising a frame (1) and panels (4) respectively welded to both sides of the frame (1), wherein a plurality of staggered spacers (2) for forming a flow channel are arranged between the panels (4), characterized in that: The side wall of the frame (1) is symmetrically provided with two groups of inlets (6) and outlets (7), and the inlets (6) and outlets (7) are both connected to the interior of the frame (1); the interior of the frame (1) is divided by a plurality of partition bars (2) to form a plurality of main flow channels (8), and a spacing bar (3) is provided in the middle of each main flow channel (8), and each spacing bar (3) divides the main flow channel (8) in which it is located into two branch flow channels (9).

2. The mixed flow double channel plate layer for a freeze dryer according to claim 1, characterized in that: Adjacent main channels (8) are connected end to end, and the end of a branch channel (9) in the same main channel (8) and the end of a branch channel (9) in an adjacent main channel (8) form a mixed flow area (5).

3. A mixed flow type double flow channel plate layer for a freeze dryer according to claim 2, characterized in that: The top end of the spacer bar (3) is provided with a guide angle (31) toward the incoming flow direction.

4. A mixed flow type double flow channel plate layer for a freeze dryer according to claim 3, characterized in that: The guide angle (31) is 45 degrees.

5. The mixed flow type double flow channel plate layer for a freeze dryer according to claim 4, characterized in that: The distance between the spacer strip (3) and the frame (1) is set to a, the width of the diversion channel (9) is set to c, and 0.5c≤a≤0.9c.

6. A mixed flow type double flow channel plate layer for a freeze dryer according to claim 5, characterized in that: The distance between the partition bar (2) and the frame (1) is set to b, where b=2a.