Cartilage repair stent

Abstract

The utility model provides a cartilage repair stent which is characterized in that a cavity is arranged inside a stent body of the cartilage repair stent, an opening is arranged on the surface of the stent body, and the cavity is communicated with the external space of the stent body through the opening; a plurality of micropores are formed in the stent body, and at least part of the micropores are communicated with the cavity and the external space of the stent body. The cartilage repair support solves the technical problem that a cartilage repair support in the prior art is poor in use flexibility.

Description

Technical Field

[0001] The utility model relates to the field of medical devices, and in particular to a cartilage repair bracket. Background Art

[0002] Articular cartilage is a transparent cartilage covering the synovial joints. It not only acts as a fulcrum, but also bears the compression force generated by adjacent joints and muscles. The shear force generated by joint movement will wear the surface of articular cartilage, so articular cartilage is more susceptible to damage. However, articular cartilage has no vascular system, lymphatic vessels and nerve innervation, and lacks storage for stem cells and growth factors. Therefore, once articular cartilage is damaged, it can hardly regenerate itself, making most of its damage irreversible.

[0003] A cartilage repair scaffold is a medical device that is implanted into bone tissue to help repair damaged cartilage. Cartilage repair scaffolds in related technologies can usually only be installed into bone tissue to allow naturally grown cartilage to attach, but have no other functions and are less flexible to use. Utility Model Content

[0004] The main purpose of the utility model is to provide a cartilage repair bracket to solve the technical problem of poor flexibility in the use of the cartilage repair bracket in the related art.

[0005] In order to achieve the above-mentioned purpose, an embodiment of the utility model provides a cartilage repair stent, wherein a cavity is provided inside the stent body of the cartilage repair stent, and an opening is provided on the surface of the stent body, and the opening connects the cavity with the external space of the stent body; a plurality of micropores are provided on the stent body, and at least some of the micropores connect the cavity with the external space of the stent body.

[0006] Furthermore, the cavity is filled with a cartilage growth promoting material, and the cartilage growth promoting material can be placed into the cavity through the opening.

[0007] Furthermore, the cartilage growth promoting material is magnesium phosphate bone cement.

[0008] Furthermore, the cartilage repair scaffold has a first end surface, and when the cartilage repair scaffold is placed in the bone tissue, the first end surface is arranged toward the cartilage surface, wherein at least a portion of the first end surface is a convexly arranged arc surface.

[0009] Furthermore, the cartilage repair scaffold has a side surface, and the side surface is adjacent to the first end surface, wherein a rounded transition is adopted at the intersection of the side surface and the first end surface.

[0010] Furthermore, a plurality of first openings are provided on the bracket body, and the first openings extend to the first end surface, wherein the optional range of the aperture of the first openings is: 0.1 mm to 0.5 mm.

[0011] Furthermore, the cartilage repair stent has a side surface, which is adjacent to the first end surface, and is provided with a plurality of second openings on the side surface, and the second openings connect the cavity and the external space of the stent body, wherein the optional range of the aperture of the second openings is: 0.2mm to 1mm.

[0012] Furthermore, a central protrusion is provided on the first end face, and the cavity includes a main body cavity section and a contraction cavity section which are interconnected, and the contraction cavity section is located on one side of the main body cavity section close to the first end face, wherein along the direction close to the first end face, the cross-sectional area of ​​at least part of the contraction cavity section is reduced.

[0013] Furthermore, the cartilage repair scaffold has a first end face, and when the cartilage repair scaffold is placed in the bone tissue, the first end face is arranged toward the cartilage surface; wherein, along the direction approaching the first end face, the cross-sectional size of the scaffold body gradually increases.

[0014] Furthermore, the cartilage repair scaffold has a side surface, the side surface is adjacent to the first end surface, the side surface includes at least a portion of a conical surface, and the angle between the generatrix of the conical surface and its central axis ranges from 1° to 5°.

[0015] Furthermore, the bracket body is manufactured by 3D printing, and the structural parameters of the bracket body satisfy at least one of the following: the diameter of the 3D printed rods ranges from 0.1 mm to 0.4 mm, the porosity of the bracket body ranges from 40% to 80%, the pore size of the micropores ranges from 100 μm to 300 μm, and the average spacing between the 3D printed rods ranges from 200 μm to 600 μm.

[0016] Furthermore, at least a portion of the outer surface of the stent body is coated with a hydroxyapatite coating.

[0017] The stent body of the cartilage repair stent using the technical solution of the utility model is provided with a cavity inside, and the surface of the stent body is provided with an opening, and the opening connects the cavity with the external space of the stent body; the stent body is provided with a plurality of micropores, and at least some of the micropores connect the cavity with the external space of the stent body. When using the above-mentioned cartilage repair stent for cartilage repair, first drill a hole in the damaged cartilage, and then implant the cartilage repair stent into the drill hole, so that the bone marrow blood of the subchondral bone seeps from the porous structure of the stent to the cartilage repair stent and forms a blood clot. The blood clot adhered to the cartilage repair stent can be transformed into new cartilage tissue about half a year after the operation, thereby realizing the repair of the damaged cartilage. Among them, a cavity is provided inside the cartilage repair stent, and the cavity is connected to the outside through the opening. The required material can be placed in the cavity through the opening to help cartilage repair. According to different actual needs, different materials can be placed in the cavity, so that the cartilage repair stent has more functions, which effectively improves the flexibility of use of the cartilage repair stent and solves the technical problem of poor flexibility of use of the cartilage repair stent in the related technology. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The drawings constituting part of the present application are used to provide a further understanding of the present invention. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation on the present invention. In the drawings:

[0019] Figure 1 This is a schematic structural diagram of an embodiment of a cartilage repair stent of the utility model at a first viewing angle;

[0020] Figure 2 It is a cross-sectional structural schematic diagram of an embodiment of a cartilage repair stent of the utility model;

[0021] Figure 3 It is a structural schematic diagram of an embodiment of the cartilage repair stent of the utility model at a second viewing angle;

[0022] Figure 4 This is a schematic diagram of the appearance structure of an embodiment of a cartilage repair stent of the utility model;

[0023] Figure 5 It is a schematic diagram of the appearance structure of an embodiment of the cartilage repair stent of the utility model at a third viewing angle.

[0024] The above drawings include the following reference numerals:

[0025] 1. Bracket body; 2. Cavity; 21. Body cavity section; 22. Contraction cavity section; 3. Opening; 4. First end face; 41. First opening; 5. Side face; 51. Second opening; 6. Second end face; 10. Micropore; 20. Rod column. DETAILED DESCRIPTION

[0026] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present application can be combined with each other. The present utility model will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0027] Please refer to Figures 1 to 5 The stent body 1 of the cartilage repair stent of the embodiment of the utility model is provided with a cavity 2 inside, and an opening 3 is provided on the surface of the stent body 1, and the opening 3 connects the cavity 2 with the external space of the stent body 1; a plurality of micropores 10 are provided on the stent body 1, and at least some of the micropores 10 connect the cavity 2 with the external space of the stent body 1.

[0028] When using the above-mentioned cartilage repair scaffold for cartilage repair, first drill a hole at the damaged cartilage, and then implant the cartilage repair scaffold into the drill hole, so that the bone marrow blood of the subchondral bone seeps out from the porous interconnected structure of the scaffold to the cartilage repair scaffold and forms a blood clot. The blood clot adhered to the cartilage repair scaffold can be transformed into new cartilage tissue about half a year after the operation, thereby achieving the repair of the damaged cartilage. Among them, a cavity 2 is set inside the cartilage repair scaffold, and the cavity 2 is connected to the outside through an opening 3. The required materials can be placed in the cavity 2 through the opening 3 to help cartilage repair. According to different actual needs, different materials can be placed in the cavity 2, so that the cartilage repair scaffold has more functions, which effectively improves the flexibility of use of the cartilage repair scaffold and solves the technical problem of poor flexibility of use of the cartilage repair scaffold in the related art.

[0029] In some optional embodiments, the cavity 2 is filled with a cartilage growth promoting material, which can be placed in the cavity 2 through the opening 3. By placing a cluster of cartilage growth materials in the cavity 2, cartilage can be promoted to form on the cartilage repair scaffold, thereby facilitating the improvement of the cartilage repair effect. Of course, other materials or drugs can also be placed in the cavity 2 according to actual needs, such as drugs to prevent infection, drugs to reduce pain, etc.

[0030] In a preferred embodiment, the cartilage growth promoting material is magnesium phosphate bone cement. Magnesium phosphate bone cement is a degradable material that can gradually degrade and slowly release magnesium ions. The increase in magnesium ion concentration promotes the proliferation of bone marrow stromal cells and enhances the expression of osteogenic genes, thereby promoting cell matrix production and mineral deposition. Bone marrow stromal cells are essential elements for cartilage growth, thereby contributing to the formation of cartilage tissue.

[0031] In this embodiment, the cartilage repair scaffold has a first end surface 4. When the cartilage repair scaffold is placed in the bone tissue, the first end surface 4 is arranged toward the cartilage surface, wherein at least a portion of the first end surface 4 is a convexly arranged arc surface.

[0032] That is to say, the upper surface of the cartilage repair stent is designed to be arc-shaped and rounded. When it is implanted in bone tissue, the upper surface of the cartilage repair stent is slightly lower than the surface of the cartilage. The arc-shaped and rounded design of the stent helps the cartilage repair stent to stimulate its joint contact surface and reduce pain for patients.

[0033] Specifically, the cartilage repair scaffold has a side surface 5 , and the side surface 5 is adjacent to the first end surface 4 , wherein a rounded transition is adopted at the intersection of the side surface 5 and the first end surface 4 .

[0034] By providing a rounded transition structure at the connection between the first end face 4 and the side face 5, the stimulation of the sharp structure of the bracket edge to the joint contact surface can be further reduced, thereby reducing the pain of the patient.

[0035] The bracket body 1 is provided with a plurality of first openings 41 , and the first openings 41 extend to the first end surface 4 , wherein the apertures of the first openings 41 may be in the range of 0.1 mm to 0.5 mm.

[0036] By setting a plurality of first openings 41 on the upper surface of the cartilage repair scaffold, on the one hand, the connection strength between the blood clot and the scaffold body 1 can be increased; on the other hand, the PRP technology (platelet-rich plasma preparation technology) can be used to inject the patient's bone marrow blood extract into the upper surface of the cartilage repair scaffold to increase the effect of cartilage repair. In a preferred embodiment, the aperture of the first opening 41 is 0.25 mm. The first opening 41 of this size can effectively improve the connection strength between the blood clot and the scaffold body 1 on the basis of ensuring the structural strength of the scaffold body 1, and has a good application effect.

[0037] In actual implementation, the number, arrangement position, depth, whether to penetrate the bracket body 1, etc. of the multiple first openings 41 can be selected according to actual needs. For example, in this embodiment, the multiple first openings 41 are evenly arranged on the first end surface 4.

[0038] In addition, the cartilage repair stent of this embodiment has a side surface 5, which is adjacent to the first end surface 4. A plurality of second openings 51 are provided on the side surface 5, and the second openings 51 connect the cavity 2 and the external space of the stent body 1, wherein the optional range of the aperture of the second openings 51 is: 0.2 mm to 1 mm.

[0039] By providing a second opening 51 on the side 5 of the cartilage repair scaffold, the tissue inside and outside the scaffold can be easily circulated inside and outside the scaffold, which is convenient for the growth of cartilage tissue. In a preferred embodiment, the aperture of the second opening 51 is 0.4 mm, and the second opening 51 of this aperture can ensure the normal circulation of substances inside and outside the scaffold without significantly affecting the structural strength of the scaffold body 1. In actual implementation, the number and position of the second openings 51 can be flexibly set according to actual needs. For example, in an optional embodiment, at least part of the side 5 is a conical surface, and the second openings 51 are multiple groups, and the number of second openings 51 in each group is multiple, and the multiple second openings 51 belonging to the same group are arranged in sequence on the side 5 along a preset trajectory, wherein the preset trajectory is inclined to the generatrix of the conical surface.

[0040] In this embodiment, the cartilage repair stent has a second end surface 6 , which is arranged opposite to the first end surface 4 , the side surface 5 is located between the first end surface 4 and the second end surface 6 , and the opening 3 is arranged on the second end surface 6 .

[0041] A central protrusion is set on the first end face 4, and the cavity 2 includes a main cavity section 21 and a contraction cavity section 22 which are interconnected. The contraction cavity section 22 is located on the side of the main cavity section 21 close to the first end face 4, wherein along the direction close to the first end face 4, the cross-sectional area of ​​at least part of the contraction cavity section 22 is reduced.

[0042] Thus, the inner surface of the cavity 2 forms a dome-like structure. The dome-like structure can make the top and sides of the hollow part inside the stent thicker than the middle, thereby ensuring the structural strength of the cartilage repair stent while ensuring that the hollow structure space is as large as possible.

[0043] In a preferred embodiment, the inner surface of the main cavity section 21 is in the shape of a cylindrical surface, and the inner surface of the contraction cavity section 22 is in the shape of an arc surface (eg, a part of a spherical surface).

[0044] In this embodiment, the cartilage repair scaffold has a first end face 4. When the cartilage repair scaffold is placed in the bone tissue, the first end face 4 is arranged toward the cartilage surface; wherein, the cross-sectional size of the scaffold body 1 gradually increases along the direction close to the first end face 4. In this way, when the cartilage repair scaffold is implanted into the opening in the bone tissue, it can be more closely fitted with the inner wall of the opening, thereby improving the connection strength between the cartilage repair scaffold and the bone tissue.

[0045] Preferably, the cartilage repair scaffold has a side surface 5, the side surface 5 is adjacent to the first end surface 4, the side surface 5 includes at least a partial conical surface, and the angle between the generatrix of the conical surface and its central axis ranges from 1° to 5°.

[0046] That is to say, in this embodiment, the stent body 1 of the cartilage repair stent is designed as an inverted cone with a certain angle (wide at the top and narrow at the bottom), and the angle is between 1° and 5°, which can ensure that the cartilage repair stent has better initial fixing strength when implanted.

[0047] In this embodiment, the bracket body 1 is manufactured by 3D printing, and the structural parameters of the bracket body 1 satisfy at least one of the following: the diameter range of the 3D printed rod column 20 is 0.1 mm to 0.4 mm, the porosity range of the bracket body 1 is 40% to 80%, the pore size range of the micropore 10 is 100 μm to 300 μm, and the average spacing between the 3D printed rod columns 20 is 200 μm to 600 μm.

[0048] like Figure 4 and Figure 5 As shown, in this preferred embodiment, the cartilage repair scaffold is made by 3D printing. The cartilage repair scaffold made by 3D printing can better produce a three-dimensional porous structure, which is closer to the trabecular structure of human bone tissue, thereby facilitating the growth and attachment of cartilage at the cartilage repair scaffold. In addition, the cartilage repair scaffold made by 3D printing can conveniently control the rod diameter, pore diameter, porosity and other parameters of the scaffold body, so that the specific structural parameters of the cartilage repair scaffold can be controlled more flexibly and accurately according to actual needs.

[0049] Preferably, the diameter of the 3D printed rod column ranges from 0.1mm to 0.4mm, the porosity of the stent body 1 ranges from 40% to 80%, the aperture of the micropores 10 ranges from 100μm to 300μm, and the average spacing between the 3D printed rod columns ranges from 200μm to 600μm. This parameter is close to the parameters of cancellous bone, which can ensure that the cartilage repair scaffold has a certain strength after implantation, and will not cause stress shielding to cause bone dissolution, so that the cartilage can grow and adhere well on it, ensuring a better cartilage repair effect.

[0050] Preferably, at least part of the outer surface of the stent body 1 is coated with a hydroxyapatite coating. By spraying the hydroxyapatite coating on part or all of the surface of the stent body 1, it can have a better bone integration effect. Specifically, by spraying the hydroxyapatite coating on the surface of the cartilage repair stent, it can have better hydrophilicity and cell adhesion. On the one hand, due to its good cell adhesion, it can promote the growth of subchondral bone and cartilage repair stent bone and improve the fixation strength of the system; on the other hand, due to its good hydrophilicity, it can promote bone marrow blood to quickly penetrate into the cartilage surface and form blood clots, which is beneficial to the subsequent cartilage formation.

[0051] From the above description, it can be seen that the above embodiments of the utility model achieve the following technical effects:

[0052] The stent body 1 of the cartilage repair stent of the embodiment of the utility model is provided with a cavity 2 inside, and an opening 3 is provided on the surface of the stent body 1, and the opening 3 connects the cavity 2 with the external space of the stent body 1; the stent body 1 is provided with a plurality of micropores 10, and at least some of the micropores 10 connect the cavity 2 with the external space of the stent body 1. When using the above-mentioned cartilage repair stent for cartilage repair, a hole is first drilled at the damaged cartilage, and then the cartilage repair stent is implanted into the drilled hole, so that the bone marrow blood of the subchondral bone seeps from the porous and connected structure of the stent into the cartilage repair stent and forms a blood clot. The blood clot adhered to the cartilage repair stent can be transformed into new cartilage tissue about half a year after the operation, thereby achieving the repair of the damaged cartilage. Among them, a cavity 2 is set inside the cartilage repair stent, and the cavity 2 is connected to the outside through an opening 3. The required materials can be placed in the cavity 2 through the opening 3 to help cartilage repair. Different materials can be placed in the cavity 2 according to actual needs, so that the cartilage repair stent has more functions, which effectively improves the flexibility of use of the cartilage repair stent and solves the technical problem of poor flexibility of use of the cartilage repair stent in related technologies.

[0053] For ease of description, spatially relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used here to describe the spatial positional relationship between a device or feature and other devices or features as shown in the figure. It should be understood that spatially relative terms are intended to include different orientations of the device in use or operation in addition to the orientation described in the figure. For example, if the device in the accompanying drawings is inverted, the device described as "above other devices or structures" or "above other devices or structures" will be positioned as "below other devices or structures" or "below other devices or structures". Thus, the exemplary term "above" can include both "above" and "below". The device can also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatially relative descriptions used here are interpreted accordingly.

[0054] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, it indicates the presence of features, steps, operations, devices, components and / or combinations thereof.

[0055] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the data used in this way can be interchangeable where appropriate, so that the embodiments of the present application described herein can be implemented in an order other than those illustrated or described herein, for example. In addition, the terms "including" and "having" and any of their variations are intended to cover non-exclusive inclusions, for example, a process, method, system, product or device that includes a series of steps or units is not necessarily limited to those steps or units that are clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.

[0056] The above description is only the preferred embodiment of the utility model, and is not intended to limit the utility model. For those skilled in the art, the utility model can have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.

Claims

1. A cartilage repair scaffold, characterized in that: The stent body (1) of the cartilage repair stent is provided with a cavity (2) inside, and the surface of the stent body (1) is provided with an opening (3), and the opening (3) connects the cavity (2) and the external space of the stent body (1); the stent body (1) is provided with a plurality of micropores (10), and at least some of the micropores (10) connect the cavity (2) and the external space of the stent body (1).

2. The cartilage repair scaffold according to claim 1, characterized in that: The cavity (2) is filled with a cartilage growth promoting material, and the cartilage growth promoting material can be placed in the cavity (2) through the opening (3).

3. The cartilage repair scaffold according to claim 2, characterized in that: The cartilage growth promoting material is magnesium phosphate bone cement.

4. The cartilage repair scaffold according to claim 1, characterized in that: The cartilage repair scaffold has a first end surface (4). When the cartilage repair scaffold is placed in bone tissue, the first end surface (4) is arranged toward the cartilage surface, wherein at least a portion of the first end surface (4) is a convexly arranged arc surface.

5. The cartilage repair scaffold according to claim 4, characterized in that: The cartilage repair scaffold has a side surface (5), and the side surface (5) is adjacent to the first end surface (4), wherein a rounded transition is adopted at the intersection of the side surface (5) and the first end surface (4).

6. The cartilage repair scaffold according to claim 4, characterized in that: The bracket body (1) is provided with a plurality of first openings (41), wherein the first openings (41) extend to the first end surface (4), wherein the aperture of the first openings (41) may be in the range of 0.1 mm to 0.5 mm.

7. The cartilage repair scaffold according to claim 4, characterized in that: The cartilage repair stent has a side surface (5), and the side surface (5) is adjacent to the first end surface (4). The side surface (5) is provided with a plurality of second openings (51), and the second openings (51) connect the cavity (2) and the external space of the stent body (1), wherein the aperture of the second openings (51) can be optionally in the range of 0.2 mm to 1 mm.

8. The cartilage repair scaffold according to claim 4, characterized in that: The first end face (4) is provided with a central protrusion, and the cavity (2) comprises a main cavity section (21) and a contraction cavity section (22) which are interconnected, and the contraction cavity section (22) is located on a side of the main cavity section (21) close to the first end face (4), wherein the cross-sectional area of ​​at least part of the contraction cavity section (22) decreases along a direction close to the first end face (4).

9. The cartilage repair scaffold according to any one of claims 1 to 3, characterized in that: The cartilage repair scaffold has a first end face (4). When the cartilage repair scaffold is placed in bone tissue, the first end face (4) is arranged toward the cartilage surface; wherein, along the direction approaching the first end face (4), the cross-sectional size of the scaffold body (1) gradually increases.

10. The cartilage repair scaffold according to claim 9, characterized in that: The cartilage repair scaffold has a side surface (5), the side surface (5) is adjacent to the first end surface (4), the side surface (5) includes at least a partial conical surface, and the angle between the generatrix of the conical surface and its central axis ranges from 1° to 5°.

11. The cartilage repair scaffold according to any one of claims 1 to 8, characterized in that: The support body (1) is manufactured by 3D printing, and the structural parameters of the support body (1) satisfy at least one of the following: the diameter of the 3D printed rod column (20) ranges from 0.1 mm to 0.4 mm, the porosity of the support body (1) ranges from 40% to 80%, the pore size of the micropores (10) ranges from 100 μm to 300 μm, and the average spacing between the 3D printed rod columns (20) ranges from 200 μm to 600 μm.

12. The cartilage repair scaffold according to any one of claims 1 to 8, characterized in that: At least part of the outer surface of the stent body (1) is coated with a hydroxyapatite coating.

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