Cell extraction device

By designing a cell extraction device that includes components such as hydraulic cylinders, lifting plates, and electric telescopic rods, the problem that hand-held syringe is difficult to maintain stability when extracting bone marrow mesenchymal stem cells is solved, and stable and efficient cell extraction is achieved.

CN222990118UActive Publication Date: 2025-06-17WEILIWEI (SHANGHAI) MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202421634303.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-10
Publication Date
2025-06-17
Estimated Expiration
2034-07-10

AI Technical Summary

Technical Problem

In the prior art, handheld syringes are difficult to maintain stability when extracting bone marrow mesenchymal stem cells, and are prone to jitter, which affects the accuracy and efficiency of cell extraction.

Method used

A cell extraction device is designed, including a base, hydraulic cylinder, lifting plate, adjustment plate, extraction cylinder, needle tube, electric telescopic rod and piston. The lifting and lowering of the lifting plate and extraction cylinder is controlled by the hydraulic cylinder. The electric telescopic rod drives the piston to stably extract cells to avoid hand-held shaking.

Benefits of technology

The stable lifting and lowering of the extraction cylinder and stable extraction of cells are achieved, which avoids cell extraction difficulties caused by hand-held shaking, and improves the accuracy and efficiency of cell extraction.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of cell extraction, and discloses a cell extraction device which comprises a base and an extraction barrel, a hydraulic cylinder is fixedly mounted at the top of the base, a lifting plate is fixedly connected to the top of the hydraulic cylinder, an adjusting plate is slidably connected to the middle of the lifting plate, a needle tube is fixedly connected to the bottom of the extraction barrel, and the needle tube is slidably connected to the middle of the lifting plate. The lower end of the needle tube is sleeved with a protective sleeve. The hydraulic cylinder works to control the lifting plate to ascend and descend, so that the lifting plate and the mounting block drive the extraction barrel to perform lifting adjustment, and the lifting plates and the limiting rods at the two ends are matched in a limiting manner in the lifting process, so that the extraction barrel can perform lifting adjustment stably, and a needle tube can be controlled to be inserted into a cell layer stably; and then the electric telescopic rod works to drive the piston to stably ascend along the interior of the extraction barrel, so that the cells can be stably extracted, the problem of shaking due to hand holding can be avoided, and the extraction work of the cells is facilitated.
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Description

Technical Field

[0001] The utility model relates to the technical field of cell extraction, and more specifically, to a cell extraction device. Background Art

[0002] Bone marrow mesenchymal stem cells refer to bone marrow stromal stem cells, which not only provide mechanical support for hematopoietic stem cells in the bone marrow, but also secrete a variety of growth factors to support hematopoiesis; currently, the main methods for extracting and separating bone marrow mesenchymal stem cells in the laboratory are the whole bone marrow method and the density gradient centrifugation method. Commonly, the density gradient centrifugation method and the whole bone marrow method are used in combination. During the density gradient centrifugation process, the liquid column in the test tube is divided into four layers after centrifugation of the bone marrow fluid. The first layer is the culture solution layer, the second layer is the mononuclear cell layer (containing the bone marrow mesenchymal stem cells to be extracted), the third layer is the lymphocyte separation solution layer, and the fourth layer is the red blood cell and multinuclear cell layer; in the prior art, a syringe is usually inserted into the cell layer to be extracted for extraction. Since the syringe needs to be held by hand, it is very difficult to keep it stable during the extraction process, and shaking will occur, which causes difficulties in the cell extraction work. Therefore, we propose a cell extraction device to solve the above problems. Summary of the Utility Model

[0003] In order to overcome the deficiencies of the prior art, the utility model provides a cell extraction device, which has the advantage of stable extraction.

[0004] To achieve the above purpose, the utility model provides the following technical solution: a cell extraction device, including a base and an extraction cylinder. A hydraulic cylinder is fixedly installed at the top of the base, and a lifting plate is fixedly connected to the top of the hydraulic cylinder. A regulating plate is slidably connected to the middle of the lifting plate. A syringe is fixedly connected to the bottom of the extraction cylinder, and a protective sleeve is sleeved on the lower end of the syringe. Legs are equidistantly installed at the top of the extraction cylinder, and an electric telescopic rod is fixedly connected to the legs. The bottom of the electric telescopic rod is fixedly connected to a piston that slides inside the extraction cylinder. An installation block is fixedly connected to the outside of the extraction cylinder.

[0005] As a preferred technical solution of the utility model, limiting rods are fixedly connected to both ends of the base, and limiting plates that slide on the limiting rods are fixedly connected to both ends of the lifting plate.

[0006] As a preferred technical solution of the utility model, a limiting pad is fixedly installed on the outside of the limiting rod.

[0007] As a preferred technical solution of the utility model, a rectangular opening is provided in the middle of the lifting plate, a first screw hole communicating with the rectangular opening is provided at the top of the lifting plate, and a first bolt is movably connected inside the first screw hole.

[0008] As a preferred technical solution of the present utility model, an installation opening for inserting the adjustment plate is provided on the installation block, and second screw holes are provided on both the installation block and the adjustment plate, and a second bolt is movably connected inside the second screw hole.

[0009] As a preferred technical solution of the present utility model, third screw holes are provided at the tops of both the support legs and the extraction cylinder, and a third bolt is movably connected inside the third screw hole.

[0010] As a preferred technical solution of the present utility model, the extraction cylinder adopts a transparent structure, and scales are provided on the outer side of the extraction cylinder.

[0011] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0012] In the present utility model, the hydraulic cylinder works to control the lifting of the lifting plate, so as to drive the extraction cylinder to perform lifting adjustment through the adjustment plate and the installation block. During the lifting process, the extraction cylinder can be stably lifted and adjusted through the limit cooperation between the limit plates at both ends and the limit rods, so as to control the syringe needle to be stably inserted into the cell layer; then, the electric telescopic rod works to drive the piston to steadily rise along the inside of the extraction cylinder, and the cells can be stably extracted, which can avoid the problem of hand shaking and is convenient for cell extraction work.

[0013] In the present utility model, the adjustment plate slides and adjusts along the inside of the rectangular opening, and then is tightened and fixed by the first bolt, so as to control the length of its outward extension, thereby controlling the adjustment of the position of the extraction cylinder, and it can be adjusted and used according to needs; by sleeving the protective sleeve on the syringe needle, it can play a protective role when not in use; by unscrewing the third bolt to disengage from the third screw hole, the support legs and the electric telescopic rod can be removed from the extraction cylinder, and then the piston can be pulled out, which is beneficial to cleaning the inside of the extraction cylinder after each work to ensure continuous use. Description of the Drawings

[0014] Figure 1 is a schematic diagram of the overall structure of the present utility model;

[0015] Figure 2 is a schematic sectional structure diagram of the present utility model;

[0016] Figure 3 is a schematic diagram of the structure at the connection between the installation block and the adjustment plate of the present utility model.

[0017] In the figure: 1, base; 2, hydraulic cylinder; 3, lifting plate; 301, first bolt; 302, rectangular opening; 303, first screw hole; 4, limiting rod; 401, limiting pad; 5, limiting plate; 6, adjusting plate; 7, mounting block; 701, second bolt; 702, mounting opening; 703, second screw hole; 8, extraction cylinder; 9, leg; 901, third screw hole; 902, third bolt; 10, electric telescopic rod; 11, syringe; 12, protective sleeve; 13, piston. Specific implementation manner

[0018] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0019] As Figures 1 to 3 shown, the present invention provides a cell extraction device, including a base 1 and an extraction cylinder 8. A hydraulic cylinder 2 is fixedly installed at the top of the base 1, the top of the hydraulic cylinder 2 is fixedly connected to a lifting plate 3, an adjusting plate 6 is slidably connected to the middle of the lifting plate 3, the bottom of the extraction cylinder 8 is fixedly connected to a syringe 11, a protective sleeve 12 is sleeved on the lower end of the syringe 11, legs 9 are equidistantly installed at the top of the extraction cylinder 8, an electric telescopic rod 10 is fixedly connected to the legs 9, the bottom of the electric telescopic rod 10 is fixedly connected to a piston 13 that slides inside the extraction cylinder 8, and a mounting block 7 is fixedly connected to the outside of the extraction cylinder 8; by the operation of the hydraulic cylinder 2 to control the lifting of the lifting plate 3, thereby driving the extraction cylinder 8 to perform lifting adjustment through the adjusting plate 6 and the mounting block 7, the extraction cylinder 8 can be stably lifted and adjusted, so that the syringe 11 can be stably inserted into the cell layer; then, by the operation of the electric telescopic rod 10 to drive the piston 13 to stably rise inside the extraction cylinder 8, cells can be stably extracted, and the problem of hand shaking can be avoided, which is convenient for cell extraction work.

[0020] Among them, limiting rods 4 are fixedly connected to both ends of the base 1, and limiting plates 5 sleeved on the limiting rods 4 and sliding are fixedly connected to both ends of the lifting plate 3;

[0021] By sleeving the limiting plates 5 at both ends on the limiting rods 4, a limiting effect can be achieved, and when the lifting plate 3 is lifted and lowered, it can be stably adjusted, improving stability.

[0022] Among them, a limiting pad 401 is fixedly installed on the outside of the limiting rod 4;

[0023] The limiting pad 401 is designed below the limiting plate 5. When the lifting plate 3 moves downward and resets, the limiting plate 5 can be placed on the limiting pad 401, which can play a load-bearing effect.

[0024] Among them, a rectangular opening 302 is formed in the middle of the lifting plate 3, and a first screw hole 303 communicating with the rectangular opening 302 is formed at the top of the lifting plate 3. A first bolt 301 is movably connected inside the first screw hole 303;

[0025] By sliding and adjusting the adjusting plate 6 along the inside of the rectangular opening 302, and then tightening the first bolt 301 to move downward along the first screw hole 303 and abut against the adjusting plate 6 for fixation, the length of its outward extension can be controlled, so as to control the adjustment of the position of the extraction cylinder 8, and it can be adjusted and used as needed.

[0026] Among them, an installation opening 702 for inserting the adjusting plate 6 is formed on the installation block 7, and second screw holes 703 are formed on both the installation block 7 and the adjusting plate 6. A second bolt 701 is movably connected inside the second screw hole 703;

[0027] One end of the adjusting plate 6 with the second screw hole 703 is inserted into the installation opening 702, and it is made to correspond to the second screw hole 703 on the installation block 7, and then the second bolt 701 is screwed in and fixed, so that the adjusting plate 6 and the installation block 7 can be stably connected together. At the same time, it is also convenient for disassembly and assembly, which is beneficial to subsequent storage and cleaning work of the extraction cylinder 8.

[0028] Among them, third screw holes 901 are formed at the tops of both the support legs 9 and the extraction cylinder 8. A third bolt 902 is movably connected inside the third screw hole 901;

[0029] By inserting the third bolt 902 into the third screw hole 901, the support legs 9 can be fixedly connected to the top of the extraction cylinder 8, which is convenient for installation and disassembly.

[0030] Among them, the extraction cylinder 8 adopts a transparent structure, and scales are arranged on the outside of the extraction cylinder 8;

[0031] By referring to the set scales, the amount of extracted cells can be controlled to avoid too much or too little.

[0032] The working principle and usage process of the present utility model:

[0033] First, it can be adjusted as needed. By sliding and adjusting the adjusting plate 6 along the inside of the rectangular opening 302, and then tightening and fixing with the first bolt 301, the length of its outward extension can be controlled, so as to control the syringe needle 11 at the bottom of the extraction cylinder 8 to be directly above the bottle mouth;

[0034] Then, the hydraulic cylinder 2 works to control the lowering of the lifting plate 3, so as to drive the extraction cylinder 8 to lower through the adjusting plate 6 and the mounting block 7. During the lowering process, the limiting plates 5 at both ends are in limiting cooperation with the limiting rods 4, so that the extraction cylinder 8 can descend stably, thereby controlling the syringe needle 11 to insert into the cell layer stably;

[0035] Then, the electric telescopic rod 10 works to drive the piston 13 to rise stably along the inside of the extraction cylinder 8, which can stably extract cells, avoid the problem of shaking caused by hand-held, and facilitate the cell extraction work.

[0036] It should be noted that in this article, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device.

[0037] Although the embodiments of the present invention have been shown and described, those of ordinary skill in the art can understand that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A cell extraction device, comprising a base (1) and an extraction cylinder (8), characterized in that: A hydraulic cylinder (2) is fixedly mounted on the top of the base (1), a lifting plate (3) is fixedly connected to the top of the hydraulic cylinder (2), an adjusting plate (6) is slidably connected to the middle of the lifting plate (3), a needle tube (11) is fixedly connected to the bottom of the extraction cylinder (8), a protective sleeve (12) is sleeved on the lower end of the needle tube (11), legs (9) are equidistantly mounted on the top of the extraction cylinder (8), an electric telescopic rod (10) is fixedly connected to the legs (9), a piston (13) that slides along the inside of the extraction cylinder (8) is fixedly connected to the bottom of the electric telescopic rod (10), and a mounting block (7) is fixedly connected to the outside of the extraction cylinder (8).

2. A cell extraction device according to claim 1, characterized in that: Both ends of the base (1) are fixedly connected to a limit rod (4), and both ends of the lifting plate (3) are fixedly connected to a limit plate (5) which is sleeved on the limit rod (4) and slides thereon.

3. A cell extraction device according to claim 2, characterized in that: A limiting pad (401) is fixedly mounted on the outside of the limiting rod (4).

4. A cell extraction device according to claim 1, characterized in that: A rectangular opening (302) is provided in the middle of the lifting plate (3), a first screw hole (303) connected to the rectangular opening (302) is provided at the top of the lifting plate (3), and a first bolt (301) is movably connected inside the first screw hole (303).

5. A cell extraction device according to claim 1, characterized in that: The mounting block (7) is provided with a mounting opening (702) for inserting the adjusting plate (6), and the mounting block (7) and the adjusting plate (6) are both provided with a second screw hole (703), and a second bolt (701) is movably connected inside the second screw hole (703).

6. A cell extraction device according to claim 1, characterized in that: The supporting legs (9) and the top of the extraction cylinder (8) are both provided with a third screw hole (901), and a third bolt (902) is movably connected inside the third screw hole (901).

7. A cell extraction device according to claim 1, characterized in that: The extraction tube (8) adopts a transparent structure, and a scale is arranged on the outer side of the extraction tube (8).