Collection and extraction equipment for stem cells

Abstract

The utility model discloses collecting and extracting equipment for stem cells, which comprises a liquid storage tube and a stem cell centrifugal machine, the bottom of the liquid storage tube is fixedly connected with a collecting needle head, and the inner wall of the liquid storage tube is slidably connected with a piston. The reset of a first spring enables a clamping groove to enter a groove and limit a fixed column, then a movable column is pushed to move downwards so as to enable a lantern ring to move, heparin is added through a conveying groove, the heparin enters a lower space of a piston through the conveying groove, a guide groove and a liquid outlet pipe, then a second fixed disc is rotated, and the heparin is conveyed into the second fixed disc. The second fixed disc rotates to drive the movable column to rotate, then the liquid outlet pipe rotates through a square rod structure close to the lower portion of the movable column and a square groove in the liquid outlet pipe, the movable column rotates to drive the mounting disc and stirring blades to rotate so that heparin and blood can be mixed, the liquid outlet pipe rotates for discharging, the mixing efficiency of heparin and blood is improved, and use is convenient.

Description

Technical Field

[0001] The utility model relates to the technical field of stem cell extraction, in particular to a collection and extraction device for stem cells. Background Art

[0002] Stem cells usually refer to cells that can self-renew infinitely. Commonly seen are totipotent stem cells, pluripotent stem cells and unipotent stem cells. And because stem cells can self-renew infinitely, stem cells have extremely broad application prospects in the field of medical health. In order to obtain stem cells for research and utilization, it is necessary to separate stem cells in blood through a stem cell collection and extraction device, and in order to avoid blood coagulation, it is necessary to mix blood with heparin.

[0003] This application is an improvement on the existing technology. In the existing technology, stem cells exist in blood. Most blood collections on the market are currently carried out through syringes. And during collection, blood is prone to coagulation. Generally, after collecting blood, staff need to add heparin to the blood to prevent coagulation, which has a cumbersome process and results in low efficiency of stem cell collection. Summary of the Utility Model

[0004] The purpose of the utility model is to solve the deficiencies existing in the prior art and to propose a collection and extraction device for stem cells.

[0005] In order to achieve the above purpose, the utility model adopts the following technical scheme:

[0006] A collection and extraction device for stem cells, including a liquid storage tube and a stem cell centrifuge. The bottom of the liquid storage tube is fixedly connected with a collection needle. The inner wall of the liquid storage tube is slidably connected with a piston. The inner wall of the piston is rotatably connected with a liquid outlet pipe. The inner wall of the liquid outlet pipe is slidably connected with a movable column. One end of the movable column extending out of the liquid outlet pipe is fixedly connected with a mounting disc. The outer wall of the mounting disc is fixedly connected with a plurality of equally spaced stirring blades along its circumferential direction. The top of the piston is fixedly connected with a fixed column slidably connected with the liquid storage tube. A conveying groove is opened in the movable column. Symmetrically distributed guiding grooves are opened on both sides of the movable column, and the guiding grooves are communicated with the conveying groove. Liquid outlet grooves are opened on both sides of the liquid outlet pipe, and the liquid outlet grooves are adapted to the guiding grooves.

[0007] As a further scheme of the utility model: A storage groove is opened at the bottom of the piston. The storage groove is adapted to the mounting disc and the stirring blades. A sealing ring is fixedly connected to the bottom inner wall of the storage groove. A sealing groove is opened at the top of the mounting disc, and the sealing groove is adapted to the sealing ring.

[0008] As a further solution of the present utility model: the lower part of the movable column is of a square rod structure, the top of the movable column is of a cylindrical structure, the outer wall of the lower part of the movable column is fixedly connected with a collar, and the collar is located inside the liquid outlet pipe. Symmetrically distributed limit blocks are arranged below the collar, and the limit blocks are fixedly connected with the inner wall of the liquid outlet pipe.

[0009] As a further solution of the present utility model: the outer wall of the top of the fixed column is fixedly connected with a first fixing plate. A sealing plug is installed at the top of the movable column, and the sealing plug is adapted to the conveying groove. The outer wall of one end of the movable column extending out of the top of the fixed column is fixedly connected with a second fixing plate. The bottom of the second fixing plate is rotatably connected with a rotating ring. The bottom of the rotating ring is fixedly connected with a second spring sleeved on the movable column, and the other end of the second spring is fixedly connected with the first fixing plate.

[0010] As a further solution of the present utility model: a plurality of equally spaced grooves are formed on one side of the fixed column. A clamping groove is slidably connected to one side of the top of the liquid storage pipe, and the clamping groove is adapted to the groove. One side of the clamping groove is fixedly connected with a first spring, and the other end of the first spring is fixedly connected with the liquid storage pipe.

[0011] As a further solution of the present utility model: the bottom of the stem cell centrifuge is fixedly connected with a workbench, and the liquid storage pipe is arranged on the workbench.

[0012] The present utility model has the following beneficial effects:

[0013] In the present utility model, when in use, the liquid storage pipe is taken to collect blood. By pulling the first fixing plate, the fixed column drives the piston to move for blood collection. After the collection is completed, the reset of the first spring makes the clamping groove enter the groove and limit the fixed column. Then, the movable column is pushed to move downward, so that the collar moves. When the collar abuts against the limit block, the guiding groove and the liquid outlet groove are on the same straight line. At this time, heparin is added thereto through the conveying groove. The heparin enters the space below the piston through the conveying groove, the guiding groove and the liquid outlet pipe. Then, the second fixing plate is rotated. The rotation of the second fixing plate drives the movable column to rotate. Furthermore, the liquid outlet pipe rotates through the square rod structure at the lower part of the movable column and the square groove on the liquid outlet pipe. The rotation of the movable column drives the mounting plate and the stirring blade to rotate, so that the heparin is mixed with the blood. The rotary feeding of the liquid outlet pipe improves the mixing efficiency of the heparin and the blood, which is convenient for use. Description of the Drawings

[0014] Figure 1 It is a schematic structural diagram of a collection and extraction device for stem cells proposed by the present utility model;

[0015] Figure 2 It is a schematic installation diagram of a stem cell centrifuge of a collection and extraction device for stem cells proposed by the present utility model;

[0016] Figure 3 is a schematic enlarged structure view of part A in the present utility model; Figure 1

[0017] Figure 4 is a schematic enlarged structure view of part B in the present utility model. Figure 1

[0018] Legend:

[0019] Liquid storage tube 1, collection needle 2, fixed column 3, movable column 4, first fixing plate 5, piston 6, conveying groove 7, guiding groove 8, collar 9, liquid outlet groove 10, liquid outlet pipe 11, limiting block 12, mounting plate 13, stirring blade 14, storage groove 15, sealing ring 16, sealing groove 17, second fixing plate 18, sealing plug 19, rotating ring 20, groove 21, first spring 22, clamping groove 23, second spring 24, workbench 25, stem cell centrifuge 26. Detailed implementation manners

[0020] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.

[0021] In the description of the present utility model, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the accompanying drawings, and is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation to the present utility model; the terms "first", "second", "third" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance. In addition, unless otherwise clearly defined and limited, the terms "installation", "connection", and "connection" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the internal communication of two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific situations.

[0022] Refer to Figures 1-4, A collection and extraction device for stem cells provided by the present utility model includes a liquid storage tube 1 and a stem cell centrifuge 26. A collection needle 2 is fixedly connected to the bottom of the liquid storage tube 1. A piston 6 is slidably connected to the inner wall of the liquid storage tube 1. A liquid outlet pipe 11 is rotatably connected to the inner wall of the piston 6. A movable column 4 is slidably connected to the inner wall of the liquid outlet pipe 11. One end of the movable column 4 extending out of the liquid outlet pipe 11 is fixedly connected to a mounting disc 13. A plurality of equally spaced stirring blades 14 are fixedly connected to the outer wall of the mounting disc 13 along its circumferential direction. A fixed column 3 slidably connected to the liquid storage tube 1 is fixedly connected to the top of the piston 6. A conveying groove 7 is formed in the movable column 4. Symmetrically distributed guiding grooves 8 are formed on both sides of the movable column 4, and the guiding grooves 8 communicate with the conveying groove 7. Liquid outlet grooves 10 are formed on both sides of the liquid outlet pipe 11, and the liquid outlet grooves 10 are adapted to the guiding grooves 8.

[0023] A receiving groove 15 is formed in the bottom of the piston 6. The receiving groove 15 is adapted to the mounting disc 13 and the stirring blades 14. A sealing ring 16 is fixedly connected to the bottom inner wall of the receiving groove 15. A sealing groove 17 is formed in the top of the mounting disc 13, and the sealing groove 17 is adapted to the sealing ring 16.

[0024] The lower part of the movable column 4 is of a square rod structure, and the top of the movable column 4 is of a cylindrical structure. A collar 9 is fixedly connected to the outer wall of the lower part of the movable column 4, and the collar 9 is located inside the liquid outlet pipe 11. Symmetrically distributed limiting blocks 12 are provided below the collar 9, and the limiting blocks 12 are fixedly connected to the inner wall of the liquid outlet pipe 11.

[0025] A first fixed disc 5 is fixedly connected to the outer wall of the top of the fixed column 3. A sealing plug 19 is installed on the top of the movable column 4, and the sealing plug 19 is adapted to the conveying groove 7. A second fixed disc 18 is fixedly connected to the outer wall of the end of the movable column 4 extending out of the top of the fixed column 3. A rotating ring 20 is rotatably connected to the bottom of the second fixed disc 18. A second spring 24 sleeved on the movable column 4 is fixedly connected to the bottom of the rotating ring 20, and the other end of the second spring 24 is fixedly connected to the first fixed disc 5.

[0026] A plurality of equally spaced grooves 21 are formed on one side of the fixed column 3. A clamping groove 23 is slidably connected to one side of the top of the liquid storage tube 1, and the clamping groove 23 is adapted to the grooves 21. A first spring 22 is fixedly connected to one side of the clamping groove 23, and the other end of the first spring 22 is fixedly connected to the liquid storage tube 1.

[0027] The bottom of the stem cell centrifuge 26 is fixedly connected to a workbench 25, and the liquid storage tube 1 is arranged on the workbench 25.

[0028] Working principle:

[0029] In this application, during use, the liquid storage tube 1 is taken to collect blood. By pulling the first fixed disk 5, the fixed column 3 drives the piston 6 to move for blood collection. After the collection is completed, the reset of the first spring 22 causes the card slot 23 to enter the groove 21 and limit the fixed column 3. Then, the movable column 4 is pushed to move downward, thereby causing the collar 9 to move. When the collar 9 abuts against the limit block 12, the guide groove 8 and the liquid outlet groove 10 are on the same straight line. At this time, heparin is added through the delivery groove 7. The heparin enters the space below the piston 6 through the delivery groove 7, the guide groove 8, and the liquid outlet pipe 11. Then, the second fixed disk 18 is rotated. The rotation of the second fixed disk 18 drives the movable column 4 to rotate. Furthermore, due to the square rod structure at the lower part of the movable column 4 and the square groove on the liquid outlet pipe 11, the liquid outlet pipe 11 rotates. The rotation of the movable column 4 drives the mounting disk 13 and the stirring blades 14 to rotate, so that the heparin is mixed with the blood. The rotational feeding of the liquid outlet pipe 11 improves the mixing efficiency of the heparin and the blood, which is convenient for use;

[0030] Among them, the square groove on the liquid outlet pipe 11 is not shown in the figure. The number of stirring blades 14 is multiple, and only two are shown in the figure.

[0031] In this application, the settings of the card slot 23, the groove 21, and the first spring 22 prevent the blood and heparin from being discharged when the movable column 4 is rotated to move the first fixed disk 5.

[0032] Finally, it should be noted that the above are only the preferred embodiments of the present utility model and are not used to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present utility model shall be included in the protection scope of the present utility model.

Claims

1. A stem cell collection and extraction device, comprising a liquid storage tube (1) and a stem cell centrifuge (26), characterized in that: The bottom of the liquid storage tube (1) is fixedly connected to a collection needle (2); the inner wall of the liquid storage tube (1) is slidably connected to a piston (6); the inner wall of the piston (6) is rotatably connected to a liquid outlet tube (11); the inner wall of the liquid outlet tube (11) is slidably connected to a movable column (4); one end of the movable column (4) extending out of the liquid outlet tube (11) is fixedly connected to a mounting plate (13); the outer wall of the mounting plate (13) is fixedly connected to a plurality of stirring blades (14) distributed at equal intervals along its circumferential direction; the top of the piston (6) is fixedly connected to a fixed column (3) slidably connected to the liquid storage tube (1); a conveying groove (7) is provided in the movable column (4); symmetrically distributed guide grooves (8) are provided on both sides of the movable column (4), and the guide grooves (8) are connected to the conveying grooves (7); liquid outlet grooves (10) are provided on both sides of the liquid outlet tube (11), and the liquid outlet grooves (10) are matched with the guide grooves (8).

2. The stem cell collection and extraction device according to claim 1, characterized in that: The bottom of the piston (6) is provided with a receiving groove (15), the receiving groove (15) is matched with the mounting plate (13), and the receiving groove (15) is matched with the stirring blade (14); a sealing ring (16) is fixedly connected to the inner wall of the bottom of the receiving groove (15), and a sealing groove (17) is provided on the top of the mounting plate (13), and the sealing groove (17) is matched with the sealing ring (16).

3. The stem cell collection and extraction device according to claim 1, characterized in that: The lower portion of the movable column (4) is a square rod structure, and the top of the movable column (4) is a cylindrical structure. A collar (9) is fixedly connected to the outer wall of the lower portion of the movable column (4), and the collar (9) is located in the liquid outlet pipe (11). A symmetrically distributed limit block (12) is provided below the collar (9), and the limit block (12) is fixedly connected to the inner wall of the liquid outlet pipe (11).

4. The stem cell collection and extraction device according to claim 1, characterized in that: The top outer wall of the fixed column (3) is fixedly connected to a first fixed plate (5); the top of the movable column (4) is provided with a sealing plug (19), and the sealing plug (19) is adapted to the conveying groove (7); the outer wall of one end of the movable column (4) extending from the top of the fixed column (3) is fixedly connected to a second fixed plate (18); the bottom of the second fixed plate (18) is rotatably connected to a rotating ring (20); the bottom of the rotating ring (20) is fixedly connected to a second spring (24) sleeved with the movable column (4); and the other end of the second spring (24) is fixedly connected to the first fixed plate (5).

5. The stem cell collection and extraction device according to claim 1, characterized in that: A plurality of grooves (21) distributed at equal intervals are formed on one side of the fixed column (3); a slot (23) is slidably connected to one side of the top of the liquid storage tube (1); the slot (23) is matched with the slot (21); a first spring (22) is fixedly connected to one side of the slot (23); and the other end of the first spring (22) is fixedly connected to the liquid storage tube (1).

6. The stem cell collection and extraction device according to claim 1, characterized in that: The bottom of the stem cell centrifuge (26) is fixedly connected to a workbench (25), and the liquid storage tube (1) is arranged on the workbench (25).

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